CN101422602B - Function food capable of improving the women cimacteric symptom - Google Patents

Function food capable of improving the women cimacteric symptom Download PDF

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CN101422602B
CN101422602B CN2008102381125A CN200810238112A CN101422602B CN 101422602 B CN101422602 B CN 101422602B CN 2008102381125 A CN2008102381125 A CN 2008102381125A CN 200810238112 A CN200810238112 A CN 200810238112A CN 101422602 B CN101422602 B CN 101422602B
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isoflavone
functional food
vitamin
improving
women
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CN101422602A (en
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董祺
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Zhongxin Nutrition and Health Industry Technology Research Institute (Shandong) Co.,Ltd.
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JINAN LAOLAISHOU BIOLOGICAL TECHNOLOGY Co Ltd
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Abstract

The invention relates to a functional food for improving female climacteric symptoms, which is characterized in that effective constituents are prepared by raw materials according to the following weight portions: 1 to 6g of soybean isoflavone, 10 to 50g of kudzu root isoflavone, 20 to 100g of collagen, 50 to 300g of whey calcium, 3 to 15g of vitamin E, 500 to 2000g of fruit of glossy privet and 500 to 2000g of raspberry. The functional food for improving female climacteric symptoms has the advantages of quick effect and significant curing effect.

Description

A kind of functional food that improves female menopause symptoms
Technical field
The present invention relates to a kind of functional food that improves female menopause symptoms.
Background technology
Female menopause symptoms is a kind of frequently-occurring disease, but does not also have a kind of specific medicament to treat at present, does not particularly have a kind ofly specificly to make functional food by pure Chinese medicine.
Summary of the invention
The object of the present invention is to provide a kind of functional food that improves female menopause symptoms, have rapid-action, the advantage of therapeutic effect.
The present invention realizes by following measure:
The present invention relates to a kind of functional food that improves female menopause symptoms, it is characterized in that effective ingredient made by following materials of weight proportions: soybean isoflavone 1~6g, Radix Puerariae isoflavone 10~50g, collagen protein 20~100g, whey calcium 50~300g, vitamin E 3~15g, Fructus Ligustri Lucidi 500~2000g, Fructus Rubi 500~2000g.
The functional food that improves female menopause symptoms of the present invention, the weight proportion of described raw material is preferably: soybean isoflavone 3g, Radix Puerariae isoflavone 23g, collagen protein 50g, whey calcium 150g, vitamin E 8g, Fructus Ligustri Lucidi 1000g, Fructus Rubi 1000g.
Clinical data
1.1 object of study
Select between 45~55 years old, menopause 5 years is with interior and perimenopausal women 90 people of climacteric syndrome symptom are arranged is object of study; Get rid of menolipsis person or person more than 55 years old more than 5 years, gestation or women breast-feeding their children, allergic constitution person, late deformity, maimed person, disability person, be associated with serious primary disease such as cardiovascular, cerebrovascular, liver, kidney and hemopoietic system, psychotic, take other related drugs, health food person that can not stop using immediately for a long time, do not meet the standard of including in, edible in accordance with regulations, can't judge curative effect and data not umbra ring effect and safety judgement person.
1.2 method
1.2.1 treatment and grouping: 90 people's randomized, double-blind are divided into two groups, younger Capsules group (functional food of the present invention) and placebo group, every group 45 people.Duration of trial 6 months, two groups on inferior index of age, the menopause time limit, body weight, motherhood distributes difference do not have significance.
1.2.2 detection index: menopausal syndrome adopts international uniform evaluation criterion Kupperman scoring questionnaire to estimate.
1.3 schedule of administration
All test-meal object oral younger capsule every day is 2 times, each 2.Cebo-Caps is mainly made by starch.
2 results
Menopause syndrome is improved situation (Kupperman scoring) and is seen Table 1 and table 2.
The Kupperman point system is according to methods of marking in Cao Zeyi chief editor's " Chinese obstetrics and gynecology " (volume two) menopause transition period and the post menopausal diseases.
Take younger capsule after 6 months, from self relatively, all 12 indexs of dosage group subjects all improve, and scoring reduces statistical significance; Matched group other indexs except Tidal fever with perspiration, insomnia and urinary system infection also make moderate progress; Take younger capsule organize after 6 months between relatively, except that depressed, dizzy, tired and these several other 8 the index dosage groups of having a headache are all obvious than the matched group improvement, statistical significance is arranged.
Table 1 is taken younger capsule Kupperman after 6 months
The change situation of every index of marking (x ± s)
Figure G2008102381125D00021
Annotate: relatively preceding with treatment *P<0.05
Table 2 is taken before and after the younger capsule 6 months (the x ± s) of comparative result between group
Annotate: compare with matched group *P<0.05
This research has especially been carried out under the fixed diet condition at northern area first at home comprehensively, and younger capsule is worked to the studies on some in dications of of climacteric women syndrome; Object of study has been screened in strictness, in the subjective symptom evaluation all 12 indexs of Kupperman scoring has all been carried out strict evaluation.The Kupperman standards of grading of the domestic improvement that this research is adopted are the quantized methods of diagnosis climacteric syndrome of generally acknowledging at present.Come the menopause syndrome of all subjects is estimated with this, taking younger capsular dosage group subjects as can be seen from the results all has improvement on all 12 indexs, statistical significance is arranged; The most of symptoms of matched group also improve, and this may be because the cause of the subjective effect that placebo produces.But the matched group improvement is not obvious on these 3 indexs of Tidal fever with perspiration, insomnia and urinary system infection, not statistically significant.And comparative effectiveness is more obvious between group, take younger capsule after 6 months except that depressed, dizzy, tired and have a headache these several, the dosage group is all improved obviously than matched group on other 8 indexs, and statistical significance is arranged.Thus, our younger as can be seen capsule improve on the climacteric syndrome symptom effect clearly, especially in that to improve in Tidal fever with perspiration and the insomnia effect more outstanding.
The functional food that improves female menopause symptoms of the present invention, have rapid-action, the significant advantage of therapeutic effect.
The specific embodiment
Embodiment 1:
Prescription: soybean isoflavone 3g Radix Puerariae isoflavone 23g collagen protein 50g whey calcium 150g vitamin E 8g Fructus Ligustri Lucidi 1000g Fructus Rubi 1000g.
Preparation method ground: Fructus Ligustri Lucidi and Fructus Rubi are mixed, add 15 times of water gagings and decoct extraction at twice, merge extracted twice liquid, concentrate and dry to such an extent that extract dried cream, to extract broken back of dried cream powder and soybean isoflavone, Radix Puerariae isoflavone, collagen protein, whey calcium, vitamin E mixes, and makes 1000 capsules.
Usage and consumption: oral, every day 2 times, each 2.
Embodiment 2:
Prescription: soybean isoflavone 5g Radix Puerariae isoflavone 15g collagen protein 90g whey calcium 80g vitamin E 4g Fructus Ligustri Lucidi 2000g Fructus Rubi 1500g.
Preparation method ground: Fructus Ligustri Lucidi and Fructus Rubi are mixed, add 15 times of water gagings and decoct extraction at twice, merge extracted twice liquid, concentrate and dry to such an extent that extract dried cream, to extract broken back of dried cream powder and soybean isoflavone, Radix Puerariae isoflavone, collagen protein, whey calcium, vitamin E mixes, and makes 1000 capsules.
Usage and consumption: oral, every day 2 times, each 2.
Embodiment 3:
Prescription: soybean isoflavone 2g Radix Puerariae isoflavone 40g collagen protein 20g whey calcium 250g vitamin e1 2g Fructus Ligustri Lucidi 1000g Fructus Rubi 600g.
Preparation method ground: Fructus Ligustri Lucidi and Fructus Rubi are mixed, add 15,10 times of water gagings respectively and decoct extraction at twice, merge extracted twice liquid, concentrate and dry to such an extent that extract dried cream, to extract broken back of dried cream powder and soybean isoflavone, Radix Puerariae isoflavone, collagen protein, whey calcium, vitamin E mixes, add appropriate amount of auxiliary materials, be pressed into tablet, amount to 1000.
Usage and consumption: oral, every day 2 times, each 2.

Claims (2)

1. functional food that improves female menopause symptoms, it is characterized in that effective ingredient made by following materials of weight proportions: soybean isoflavone 1~6g, Radix Puerariae isoflavone 10~50g, collagen protein 20~100g, whey calcium 50~300g, vitamin E 3~15g, Fructus Ligustri Lucidi 500~2000g, Fructus Rubi 500~2000g.
2. the functional food that improves female menopause symptoms according to claim 1 is characterized in that the weight proportion of described raw material is: soybean isoflavone 3g, Radix Puerariae isoflavone 23g, collagen protein 50g, whey calcium 150g, vitamin E 8g, Fructus Ligustri Lucidi 1000g, Fructus Rubi 1000g.
CN2008102381125A 2008-12-08 2008-12-08 Function food capable of improving the women cimacteric symptom Active CN101422602B (en)

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Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102755521B (en) * 2012-07-31 2014-01-29 施慧达药业集团(吉林)有限公司 Chinese materia medica preparation for treating climacteric syndrome and preparation method thereof
CN106418319A (en) * 2016-09-09 2017-02-22 杨森健 Functional food used for relieving climacteric syndrome and application thereof
CN109998097A (en) * 2019-04-22 2019-07-12 吉林省华惠生物科技有限公司 It is a kind of for improving the health care product and preparation method of Woman climacteric symptom

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1123145A (en) * 1994-11-18 1996-05-29 孙念怙 Medicinal compound for curing women's involutional syndrome
CN1127643A (en) * 1995-01-28 1996-07-31 杭州商学院 Woman climacteric function food and its producing method
CN1481865A (en) * 2003-07-18 2004-03-17 武汉名实生物医药科技有限责任公司 Complex plant estrogen formulation which can delay female senility and method preparing same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1123145A (en) * 1994-11-18 1996-05-29 孙念怙 Medicinal compound for curing women's involutional syndrome
CN1127643A (en) * 1995-01-28 1996-07-31 杭州商学院 Woman climacteric function food and its producing method
CN1481865A (en) * 2003-07-18 2004-03-17 武汉名实生物医药科技有限责任公司 Complex plant estrogen formulation which can delay female senility and method preparing same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
吴大伟等.一种延缓衰老胶囊的安全性研究.《卫生毒理学杂志》.2003,第17卷(第3期),191-192. *

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