CN103339261B - 通过重组微生物从一氧化碳产生丁醇 - Google Patents
通过重组微生物从一氧化碳产生丁醇 Download PDFInfo
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- CN103339261B CN103339261B CN201180062114.3A CN201180062114A CN103339261B CN 103339261 B CN103339261 B CN 103339261B CN 201180062114 A CN201180062114 A CN 201180062114A CN 103339261 B CN103339261 B CN 103339261B
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- butanol
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/16—Butanols
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/145—Clostridium
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40587110P | 2010-10-22 | 2010-10-22 | |
| US61/405,871 | 2010-10-22 | ||
| US13/049,263 US20110236941A1 (en) | 2010-10-22 | 2011-03-16 | Recombinant microorganism and methods of production thereof |
| US13/049,263 | 2011-03-16 | ||
| PCT/NZ2011/000203 WO2012053905A1 (en) | 2010-10-22 | 2011-09-29 | Production of butanol from carbon monoxide by a recombinant microorganism |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103339261A CN103339261A (zh) | 2013-10-02 |
| CN103339261B true CN103339261B (zh) | 2017-03-29 |
Family
ID=44656929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201180062114.3A Active CN103339261B (zh) | 2010-10-22 | 2011-09-29 | 通过重组微生物从一氧化碳产生丁醇 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20110236941A1 (enExample) |
| EP (1) | EP2630247B1 (enExample) |
| JP (1) | JP6014042B2 (enExample) |
| KR (2) | KR20130079599A (enExample) |
| CN (1) | CN103339261B (enExample) |
| AU (1) | AU2011318676B2 (enExample) |
| CA (1) | CA2813431C (enExample) |
| DK (1) | DK2630247T3 (enExample) |
| EA (1) | EA028760B1 (enExample) |
| ES (1) | ES2626448T3 (enExample) |
| MY (1) | MY157111A (enExample) |
| NZ (1) | NZ609150A (enExample) |
| WO (1) | WO2012053905A1 (enExample) |
| ZA (1) | ZA201302898B (enExample) |
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| US20110256600A1 (en) * | 2011-02-02 | 2011-10-20 | Lanzatech New Zealand Limited | Recombinant Microorganisms and Methods of Use Thereof |
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| NZ700609A (en) * | 2012-04-05 | 2016-07-29 | Lanzatech New Zealand Ltd | Enzyme-altered metabolite activity |
| US20130323820A1 (en) * | 2012-06-01 | 2013-12-05 | Lanzatech New Zealand Limited | Recombinant microorganisms and uses therefor |
| JP6381525B2 (ja) * | 2012-06-08 | 2018-08-29 | ランザテク・ニュージーランド・リミテッド | 組換え微生物およびその使用 |
| US9347076B2 (en) * | 2012-06-21 | 2016-05-24 | Lanzatech New Zealand Limited | Recombinant microorganisms that make biodiesel |
| EP2872641B1 (en) | 2012-07-13 | 2018-03-28 | Calysta, Inc. | Biorefinery system, methods and compositions thereof |
| WO2014036152A1 (en) | 2012-08-28 | 2014-03-06 | Lanzatech New Zealand Limited | Recombinant microorganisms and uses therefor |
| WO2014047209A1 (en) * | 2012-09-18 | 2014-03-27 | Calysta Energy, Inc. | Propylene synthesis using engineered enzymes |
| WO2014058761A1 (en) | 2012-10-08 | 2014-04-17 | Calysta Energy, Llc | Gas-fed fermentation systems |
| US9469860B2 (en) * | 2013-01-18 | 2016-10-18 | Synata Bio, Inc. | Method for production of n-butanol from syngas using syntrophic co-cultures of anaerobic microorganisms |
| PT2951286T (pt) | 2013-01-30 | 2023-11-02 | Lanzatech Nz Inc | Microrganismos recombinantes que compreedem enzimas dependentes de nadph e métodos de produção dos mesmos |
| JP2014161252A (ja) * | 2013-02-22 | 2014-09-08 | Sekisui Chem Co Ltd | 組換え細胞 |
| EP2774986A1 (en) * | 2013-03-06 | 2014-09-10 | Clariant Produkte (Deutschland) GmbH | Improvement of clostridial butanol production by gene overexpression |
| US9045758B2 (en) | 2013-03-13 | 2015-06-02 | Coskata, Inc. | Use of clostridial methyltransferases for generating novel strains |
| BR112015030208A2 (pt) * | 2013-06-05 | 2017-08-22 | Lanzatech New Zealand Ltd | Métodos para produzir um produto de fermentação e um micro-organismo, e, micro-organismo recombinante |
| ES2876228T3 (es) | 2013-06-18 | 2021-11-12 | Evonik Operations Gmbh | Procedimiento y dispositivo para el almacenamiento de energía excedente |
| SG11201601263WA (en) | 2013-09-12 | 2016-03-30 | Lanzatech New Zealand Ltd | Recombinant microorganisms and methods of use thereof |
| CN105940100A (zh) * | 2014-01-28 | 2016-09-14 | 朗泽科技新西兰有限公司 | 对丁酸具有增加的耐受性的细菌 |
| HUE051262T2 (hu) | 2014-01-28 | 2021-03-01 | Lanzatech New Zealand Ltd | Módszer rekombináns mirkoorganizmus elõállítására |
| CN106133132A (zh) | 2014-01-30 | 2016-11-16 | 朗泽科技新西兰有限公司 | 重组微生物和其使用方法 |
| WO2015138977A2 (en) * | 2014-03-14 | 2015-09-17 | Ohio State Innovation Foudation | Metabolic engineering of clostridium for biofuel production |
| US10920253B2 (en) | 2014-03-26 | 2021-02-16 | Scientist of Fortune, S.A. | Enzymatic production of acetyl phosphate from formaldehyde |
| KR20240160674A (ko) | 2014-10-22 | 2024-11-11 | 란자테크 엔지, 인크. | 가스 시험 유닛 및 방법 |
| EA035153B1 (ru) | 2014-10-22 | 2020-05-06 | Ланцатек Нью Зилэнд Лимитед | Многостадийные биореакторные процессы |
| PT3230459T (pt) * | 2014-12-08 | 2020-12-18 | Lanzatech New Zealand Ltd | Microrganismos recombinantes que exibem fluxo aumentado através de uma via de fermentação |
| US10131884B2 (en) | 2015-02-23 | 2018-11-20 | Lanzatech New Zealand Limited | Recombinant acetogenic bacterium for the conversion of methane to products |
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| AU2016339989B2 (en) * | 2015-10-13 | 2022-11-17 | Lanzatech Nz, Inc. | Genetically engineered bacterium comprising energy-generating fermentation pathway |
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| US10358661B2 (en) | 2015-12-28 | 2019-07-23 | Lanzatech New Zealand Limited | Microorganism with modified hydrogenase activity |
| KR20180118651A (ko) | 2016-02-01 | 2018-10-31 | 란자테크 뉴질랜드 리미티드 | 통합형 발효 및 전해 공정 |
| WO2017147555A1 (en) | 2016-02-26 | 2017-08-31 | Lanzatech New Zealand Limited | Crispr/cas systems for c-1 fixing bacteria |
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| SG11201810031RA (en) | 2016-05-14 | 2018-12-28 | Lanzatech Inc | Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methods |
| US11976314B2 (en) * | 2017-08-29 | 2024-05-07 | Gwangju Institute Of Science And Technology | Method for converting non-ethanol producing, acetogenic strain to ethanol-producing strain and method for producing ethanol from same ethanol-producing strain by using carbon monoxide |
| CN107460148B (zh) * | 2017-09-01 | 2020-12-25 | 湖州至美生物科技有限公司 | 一种枯草芽孢杆菌菌粉的制备方法及应用 |
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Citations (1)
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|---|---|---|---|---|
| US20100151543A1 (en) * | 2008-12-16 | 2010-06-17 | Andrew Reeves | Recombinant microorganisms having modified production of alcohols and acids |
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- 2011-09-29 CN CN201180062114.3A patent/CN103339261B/zh active Active
- 2011-09-29 KR KR1020137012815A patent/KR20130079599A/ko not_active Ceased
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- 2011-09-29 ES ES11834686.5T patent/ES2626448T3/es active Active
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Also Published As
| Publication number | Publication date |
|---|---|
| CA2813431C (en) | 2014-09-09 |
| CA2813431A1 (en) | 2012-04-26 |
| US9359611B2 (en) | 2016-06-07 |
| ES2626448T3 (es) | 2017-07-25 |
| CN103339261A (zh) | 2013-10-02 |
| EA201390444A1 (ru) | 2013-11-29 |
| AU2011318676B2 (en) | 2014-07-03 |
| US20110236941A1 (en) | 2011-09-29 |
| AU2011318676A1 (en) | 2013-05-02 |
| BR112013009552A2 (pt) | 2016-07-19 |
| KR20140012212A (ko) | 2014-01-29 |
| EP2630247A4 (en) | 2014-05-07 |
| MY157111A (en) | 2016-05-13 |
| JP6014042B2 (ja) | 2016-10-25 |
| EA028760B1 (ru) | 2017-12-29 |
| EP2630247B1 (en) | 2017-03-15 |
| KR20130079599A (ko) | 2013-07-10 |
| DK2630247T3 (en) | 2017-06-26 |
| JP2013543724A (ja) | 2013-12-09 |
| NZ609150A (en) | 2015-02-27 |
| ZA201302898B (en) | 2014-12-23 |
| US20140186928A1 (en) | 2014-07-03 |
| EP2630247A1 (en) | 2013-08-28 |
| WO2012053905A1 (en) | 2012-04-26 |
| KR101640325B1 (ko) | 2016-07-15 |
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