CN103301250B - A kind of herbal composite preventing and treating Fish balantidiasis - Google Patents
A kind of herbal composite preventing and treating Fish balantidiasis Download PDFInfo
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- CN103301250B CN103301250B CN201310222832.3A CN201310222832A CN103301250B CN 103301250 B CN103301250 B CN 103301250B CN 201310222832 A CN201310222832 A CN 201310222832A CN 103301250 B CN103301250 B CN 103301250B
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Abstract
The present invention relates to a kind of herbal composite preventing and treating Fish balantidiasis, make primarily of Rhizoma Coptidis, Fructus Toosendan, Semen Cucurbitae, Herba Verbenae, Radix Notoginseng.The present invention forms according to Chinese veterinarian's abstract science prescription, has significant effect to the prevention and therapy of Fish balantidiasis, and total effective rate can reach more than 80%, can be prepared into the dosage forms such as powder, oral solution and granule.
Description
Technical field
The present invention relates to a kind of herbal composite for animals, be specifically related to a kind of herbal composite preventing and treating Fish balantidiasis.
Background technology
Fish balantidiasis causes primarily of ciliate parasitisms such as Zoothamnium, tired branch worm, vorticellas.South all can occur the whole year, and 7 ~ November is onset peak period.All aquaculture kinds all can be parasitic by ciliate.If the fry body constitution of newly buying is more weak or unhealthy, adds reasons such as changing to new water environment, easily bring out balantidiasis.In breeding process, due to variations in temperature, water quality is muddy, and pollutant such as to enter at the reason, cause breeding environment to worsen, cause balantidiasis to occur.In addition, in feeding process, the generation that rotten feedstuff or feed additive add is improper, abuse disinfectant and antibiotic also easily cause balantidiasis.The disease time two weeks at least of balantidiasis, one or two months at most, disease time was very long.When dissolved oxygen in water is lower, mortality can be caused.
As far back as 20 beginnings of the century, Fish balantidiasis just causes the great attention of domestic and international fish diseases scholar, also achieves some achievements to the control of this disease.But up to now, the balantidiasis of Fish is not also controlled effectively, there is the difficult situation of " handy medicine is dangerous, and safe drugs are not handy ".In China, the traditional method of control balantidiasis is the formalin frequently using high concentration, use formalin can only kill the ciliate on ill fish surface, for the polypide in intrusive body then without effect, and high concentration uses Fish tissue can be caused to damage, and edible fish residues of formaldehyde and serious environmental pollution.The ciliophoran medicine of fish body killed by exploitation Chinese medicine, and the medication not only can enriching aquaculture is selected, and can also play the advantage that Chinese medicine has no drug resistance, drug residue free, drug effect are permanent, have wide market prospect.
Summary of the invention
The invention provides a kind of herbal composite, for preventing and treating Fish balantidiasis.The present invention is achieved in that
Prevent and treat a herbal composite for Fish balantidiasis, it is characterized in that, it is made up of the raw material of following weight portion: Rhizoma Coptidis 3 ~ 5 parts, Fructus Toosendan 3 ~ 5 parts, Semen Cucurbitae 1 ~ 3 part, Herba Verbenae 4 ~ 8 parts, Radix Notoginseng 3 ~ 5 parts.This herbal composite is preferably by weight: Rhizoma Coptidis 4 parts, Fructus Toosendan 4 parts, Semen Cucurbitae 2 parts, Herba Verbenae 6 parts, Radix Notoginseng 4 parts.
The herbal composite that the present invention is above-mentioned, dosage form is powder.Said herbal medicine raw material is made after mixing, micronizing the brown powder that granularity is less than 10 μm.
The herbal composite that the present invention is above-mentioned, dosage form also can be oral solution, granule.
The herbal composite that the present invention is above-mentioned, can also comprise following pharmacopedics can adjuvant: as antioxidant, antiseptic, binding agent, solvent, solubilizing agent, cosolvent, sweeting agent, correctives, excipient etc.
This prescription medical material effect is resolved as follows:
Rhizoma Coptidis, herbaceos perennial, belong to Ranunculaceae Coptis, being one of 40 kinds of large Chinese crude drugs, is also one of 30 kinds of rare Chinese medicines.Property bitter, cold, nontoxic, GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel, have heat clearing and damp drying, effect of eliminating fire and detoxication.
Fructus Toosendan is the dry mature fruit of Meliaceae plant chinaberry, feeble QI and special, and sour in the mouth is then bitter, effect of tool promoting the circulation of QI to relieve pain, parasite killing.
Semen Cucurbitae is the seed of the annual liana Fructus Cucurbitae moschatae of overgrowing of Cucurbitaceae.Main product in Zhejiang, Jiangsu, Hebei, Shandong, Shanxi, the ground such as Sichuan, main uses is anthelmintic.
Herba Verbenae is the dry aerial parts of Verbenaceae Herba Verbenae, is distributed in the ground such as Shanxi, Shaanxi, Gansu, Xinjiang, Jiangsu, Anhui, Zhejiang, Jiangxi, Fujian, and property is bitter, cool, returns liver, spleen channel." Bencao Jingshu " is recorded, and it has effect of removing heat from blood removing blood stasis, parasite killing anthelmintic.
Radix Notoginseng is the dry root of panax araliaceae plant, sweet in the mouth, micro-hardship, warm in nature.There is the function of hemostasis, loose blood, analgesic therapy.
The present invention is creatively by antidote Rhizoma Coptidis, parasite killing Fructus Toosendan, Semen Cucurbitae, Herba Verbenae and hemorrhage Radix Notoginseng prescription, through pharmacodynamics test checking for several times, above-mentioned Chinese medicine composition is used, effect of Chinese medicine ingredients can be improved to greatest extent, play Chinese medicine complementation and castering action, improve parasite killing and insect-expelling function.
Detailed description of the invention
Embodiment 1:
In the present embodiment Chinese medicine composition, principal agent Parts by Ingredients ratio is: Rhizoma Coptidis 3 parts, Fructus Toosendan 3 parts, Semen Cucurbitae 1 part, Herba Verbenae 4 parts, Radix Notoginseng 3 parts.
By above-mentioned each component micronizing (granularity is less than 10 μm) mix homogeneously by weight proportion respectively, be prepared into powder.
Embodiment 2:
In the present embodiment Chinese medicine composition, principal agent Parts by Ingredients ratio is: Rhizoma Coptidis 5 parts, Fructus Toosendan 5 parts, Semen Cucurbitae 3 parts, Herba Verbenae 8 parts, Radix Notoginseng 5 parts.
By above-mentioned each component micronizing (granularity is less than 10 μm) mix homogeneously by weight proportion respectively, be prepared into powder.
Embodiment 3:
In the present embodiment Chinese medicine composition, principal agent Parts by Ingredients ratio is: Rhizoma Coptidis 4 parts, Fructus Toosendan 4 parts, Semen Cucurbitae 2 parts, Herba Verbenae 6 parts, Radix Notoginseng 4 parts.
Above-mentioned each component is decocted with water, is prepared into oral liquid.
Embodiment 4:
In the present embodiment Chinese medicine composition, principal agent Parts by Ingredients ratio is: Rhizoma Coptidis 3 parts, Fructus Toosendan 5 parts, Semen Cucurbitae 1 part, Herba Verbenae 7 parts, Radix Notoginseng 5 parts.
By above-mentioned each component decocting or ethanol extraction, add the adjuvants such as starch, sucrose, sorbic acid, be prepared into granule.
Be described in detail specific embodiments of the invention above, but it is just as example, the present invention is not restricted to specific embodiment described above.To those skilled in the art, any equivalent modifications that the present invention is carried out and substituting also all among category of the present invention.Therefore, not departing from the equalization conversion and amendment done under spirit of the present invention and category, all should contain within the scope of the invention.
Claims (3)
1. prevent and treat a herbal composite for Fish balantidiasis, it is characterized in that being prepared from by the Chinese herbal medicine of following weight portion: Rhizoma Coptidis 3 ~ 5 parts, Fructus Toosendan 3 ~ 5 parts, Semen Cucurbitae 1 ~ 3 part, Herba Verbenae 4 ~ 8 parts, Radix Notoginseng 3 ~ 5 parts.
2. a kind of herbal composite preventing and treating Fish balantidiasis as claimed in claim 1, is further characterized in that containing antioxidant, antiseptic, binding agent, solvent, solubilizing agent, cosolvent, sweeting agent, correctives or excipient.
3. a kind of herbal composite preventing and treating Fish balantidiasis as described in any one of claim 1 ~ 2, is further characterized in that former for crude drug powder or extract, directly or again adds pharmaceutic adjuvant, be prepared into powder, oral solution or granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310222832.3A CN103301250B (en) | 2013-06-06 | 2013-06-06 | A kind of herbal composite preventing and treating Fish balantidiasis |
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| CN201310222832.3A CN103301250B (en) | 2013-06-06 | 2013-06-06 | A kind of herbal composite preventing and treating Fish balantidiasis |
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| Publication Number | Publication Date |
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| CN103301250A CN103301250A (en) | 2013-09-18 |
| CN103301250B true CN103301250B (en) | 2015-08-12 |
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| CN201310222832.3A Expired - Fee Related CN103301250B (en) | 2013-06-06 | 2013-06-06 | A kind of herbal composite preventing and treating Fish balantidiasis |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105816579A (en) * | 2016-05-15 | 2016-08-03 | 镇江荣邦生物科技有限公司 | Traditional Chinese medicine preparation for preventing and treating taeniasis solium |
| CN106943580A (en) * | 2017-03-30 | 2017-07-14 | 青岛海之星生物科技有限公司 | Treat environmentally friendly preparation of compound of mandarin fish balantidiasis and preparation method thereof |
| CN108159194A (en) * | 2017-12-08 | 2018-06-15 | 武汉中博水产生物技术有限公司 | A kind of Verbena officinalis preparation and its application for being used to prevent Dactylogyrus |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1150382A (en) * | 1994-06-16 | 1997-05-21 | 山之内制药株式会社 | Feed containing crude drug |
| CN1762460A (en) * | 2005-09-23 | 2006-04-26 | 中国水产科学研究院黄海水产研究所 | The Chinese herbal medicine compound prescription of control seawater fish shield balantidiasis |
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2013
- 2013-06-06 CN CN201310222832.3A patent/CN103301250B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1150382A (en) * | 1994-06-16 | 1997-05-21 | 山之内制药株式会社 | Feed containing crude drug |
| CN1762460A (en) * | 2005-09-23 | 2006-04-26 | 中国水产科学研究院黄海水产研究所 | The Chinese herbal medicine compound prescription of control seawater fish shield balantidiasis |
Non-Patent Citations (1)
| Title |
|---|
| 海水鱼盾纤毛虫病药物研究获突破;鲁彦;《中国渔业报》;19231020;004 * |
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Granted publication date: 20150812 Termination date: 20180606 |