CN103272153A - Antibacterial gel and preparation method thereof - Google Patents
Antibacterial gel and preparation method thereof Download PDFInfo
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- CN103272153A CN103272153A CN2013102605288A CN201310260528A CN103272153A CN 103272153 A CN103272153 A CN 103272153A CN 2013102605288 A CN2013102605288 A CN 2013102605288A CN 201310260528 A CN201310260528 A CN 201310260528A CN 103272153 A CN103272153 A CN 103272153A
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Abstract
The invention relates to the technical field of antibacterial gel, in particular to antibacterial gel and a preparation method thereof. The antibacterial gel per liter comprises the following raw materials: 1.7-1.9g benzalkonium chloride, 30-50ml glycerol, 0.1-1.3g menthol, 1-1.8g alums, 0.3-0.4g lactic acid, 2.5-5g carbomer, 3-6g traditional Chinese medicine extract and the balance of purified water. The antibacterial gel contains various anti-inflammatory, antibacterial and analgesic components; an antibacterial effect is best through a synergistic effect of the raw materials; the biocompatibility of the antibacterial gel meets GB/T 16886.11-2011; a microbiological indicator of the antibacterial gel meets GB 15979-2002; and the antibacterial gel is suitable for nursing of various vaginal bacterial infection, trichomonas infection, leukorrhea, monilial infection, cervix and genital tract or mucosal wound surface infection, promotes healing of a wound surface after cervical erosion physiotherapy, and is further suitable for internal hemorrhoid, external hemorrhoid, mixed hemorrhoid, anal fissure and anorectal postoperative nursing.
Description
Technical field
The present invention relates to antibacterial gel technique field, be specifically related to a kind of antibacterial gel and preparation method thereof.
Background technology
Gynaecopathia is such as vaginitis etc. and hemorrhoid some common frequently-occurring diseases normally, usually and obstinate, brings great inconvenience for normal life, work.
At present, gynecological's medicine and hemorrhoid medicine on the market are a feast for the eyes, Patent data also has introduces bacteriostatic, be that 201210039685.1 Chinese invention patent has been introduced a kind of germicide for skin and preparation method thereof as application number, described germicide for skin comprises Folium Ginkgo juice, Flos Chrysanthemi juice, white Radix Solani Melongenae juice, Radix Puerariae juice, Folium Artemisiae Argyi juice, juice of Herba Portulacae, very light blue juice, components such as distilled water, its production stage comprises: with Folium Ginkgo juice, Flos Chrysanthemi juice, white Radix Solani Melongenae juice, Radix Puerariae juice, Folium Artemisiae Argyi juice, juice of Herba Portulacae, very light blue juice, distilled water mixes, and stir, heated 6-8 hour, temperature is 65-70 ℃, in mixed solution, add auxiliary material then, make it that catalytic reaction take place, in catalytic reaction process, undertaken detecting from motion tracking by the biological monitoring instrument in the catalyst reaction device, namely get germicide for skin at last.
But above antibacterial fungistatic effect is poor, and can not effectively treat gynaecopathia and hemorrhoid.
Summary of the invention
The objective of the invention is at the deficiencies in the prior art, a kind of antibacterial gel of good antimicrobial effect is provided.
To achieve these goals, the present invention adopts following technical scheme: a kind of antibacterial gel, and every liter of antibacterial gel is made up of following raw material:
Benzalkonium chloride 1.7-1.9g
Glycerol 30-50ml
Menthol 0.1-1.3g
Alumen 1-1.8g
Lactic acid 0.3-0.4g
Carbomer 2.5-5g
Chinese medicine extract 3-6g
The purified water surplus.
Preferably, every liter of antibacterial gel is made up of following raw material:
Benzalkonium chloride 1.8-1.9g
Glycerol 40-50ml
Menthol 0.5-1.3g
Alumen 1.5-1.8g
Lactic acid 0.3-0.4g
Carbomer 3.5-5g
Chinese medicine extract 4-6g
The purified water surplus.
More preferred, every liter of antibacterial gel is made up of following raw material:
Benzalkonium chloride 1.8g
Glycerol 40ml
Menthol 0.5g
Alumen 1.5g
Lactic acid 0.3g
Carbomer 3.5g
Chinese medicine extract 4g
The purified water surplus.
A kind of cationic surfactant of described benzalkonium chloride, belong to non-oxidizable antibacterial, have wide spectrum, sterilizing ability efficiently, can change antibacterial endochylema membrane permeability, thalline endochylema material is exosmosed, hinder its metabolism and play killing action, stronger to the gram-positive bacteria effect, can with the rapid combination of protein.
Menthol of the present invention is natural menthol, and the traditional Chinese medical science shows that Herba Menthae has dispelling wind, dispels the heat, wards off effect dirty, detoxifcation, and menthol mainly plays anti-inflammation, analgesic effect extremely in the present invention.
Glycerol of the present invention is as hygroscopic agent, viscosity modifier and solvent.
Alumen of the present invention has inhibitory action to multiple Grain-negative, positive coccus and bacillus; Common suppuration bacterium there is strong bacteriostasis.Also have effects such as convergence, anti-trichomonas vaginitis, coagulated protein in addition.
Lactic acid of the present invention has the effect of sterilization, anticorrosion, hydrotropy, PH regulator.
Carbomer of the present invention plays the effect of thickening agent, in order to make the present invention be gel.
Be rich in multiple antiinflammatory, antibiotic, analgesic composition in the Chinese medicine extract of the present invention.
Preferably, described Chinese medicine extract is formed by the raw material extraction of following weight portion:
Radix Scutellariae 10-30 part
Cortex Phellodendri 10-30 part
Rhizoma Smilacis Glabrae 10-30 part
Semen Momordicae 10-30 part
Folium Artemisiae Argyi 10-30 part
Radix Sophorae Flavescentis 10-30 part
Fructus Cnidii 10-30 part
Cortex Dictamni 10-30 part.
Radix Scutellariae has heat clearing and damp drying, and removing heat from blood is antiabortive, detoxicating functions, and in clinical practice, the antibiotic property of Radix Scutellariae is not worse than Rhizoma Coptidis, and does not develop immunity to drugs.
Cortex Phellodendri has heat clearing and damp drying, and eliminating fire and detoxication is except the effect of hectic fever due to YIN-deficiency clearind deficient heat.Contain main components such as berberine, obacunone in the Cortex Phellodendri, the effect of antibiotic, convergence, antiinflammatory is arranged, to symptoms such as various skin noxious dampness, skin infection, effect is good.
Rhizoma Smilacis Glabrae has dehumidifying, detoxifcation, the effect of easing joint movement.Be used for damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, the limbs contracture due to the scrofula, scabies, syphilis and mercurialism, bones and muscles pain.
Semen Momordicae has dispersing swelling and dissipating binds, the effect of the poison of dispelling.Be used for controlling carbuncle, furuncle, scrofula, hemorrhoid, innominate toxic swelling, tinea skin ulcer, rheumatic arthralgia, the contracture of muscle arteries and veins.
The Folium Artemisiae Argyi blood of regulating the flow of vital energy is by cold-damp; Warming the meridian, hemostasis, antiabortive.Dispersing cold for relieving pain, warming the meridian for stopping bleeding.Be used for few abdomen cold type of pain, coldness and unbalance in meridians, cold womb is infertile, spits blood, epistaxis, the metrorrhagia warp is many, gestation hemorrhage; The external treatment skin pruritus, decortication.
Radix Sophorae Flavescentis has heat clearing and damp drying, parasite killing, the effect of diuresis.Be used for hematodiarrhoea, have blood in stool jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis.Antibacterial action: Radix Sophorae Flavescentis ether extract and ethanol extract have stronger bacteriostasis to staphylococcus aureus; Radix Sophorae Flavescentis water logging agent has inhibitory action to trichophyton, Trichophyton concentricunm, trichophyton, Du's big belly budlet spore tinea bacterium difficult to understand etc.
Fructus Cnidii, detoxifcation parasite killing dampness is dispeled the wind.The external treatment vulval eczema, married woman's pudendal pruritus, trichomonal vaginitis, eczema scabies, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago, impotence due to deficiency of the kidney, cold womb are infertile.
Cortex Dictamni has heat clearing and damp drying, the effect of the detoxifcation of dispeling the wind." property of medicine opinion ": " control all pyretic toxicity wind, aversion to wind, wind skin ulcer, scabies are red mashed, and the eyebrow loss of hairs is crisp, and musculus cutaneus is anxious, and the high fever aversion to cold to multiple pathomycete such as trichophyton, Trichophyton concentricunm, oidium schoenleinii, all has inhibitory action in various degree.
More preferred, described Chinese medicine extract is formed by the raw material extraction of following weight portion:
Radix Scutellariae 10-20 part
Cortex Phellodendri 20-30 part
Rhizoma Smilacis Glabrae 20-30 part
Semen Momordicae 10-20 part
Folium Artemisiae Argyi 10-20 part
Radix Sophorae Flavescentis 20-30 part
Fructus Cnidii 20-30 part
Cortex Dictamni 10-20 part.
Or described Chinese medicine extract is formed by the raw material extraction of following weight portion:
Radix Scutellariae 20-30 part
Cortex Phellodendri 10-20 part
Rhizoma Smilacis Glabrae 10-20 part
Semen Momordicae 20-30 part
Folium Artemisiae Argyi 20-30 part
Radix Sophorae Flavescentis 10-20 part
Fructus Cnidii 10-20 part
Cortex Dictamni 20-30 part.
Another object of the present invention provides a kind of preparation method of antibacterial gel, and it comprises following preparation process:
The preparation of steps A, Chinese medicine extract: Radix Scutellariae, Cortex Phellodendri, Rhizoma Smilacis Glabrae, Semen Momordicae, Folium Artemisiae Argyi, Radix Sophorae Flavescentis, Fructus Cnidii, the Cortex Dictamni of above-mentioned formula ratio are added the purified water refinement, cross leaching filtrate, concentrated, dry, obtain Chinese medicine extract;
Step B, weighing: the benzalkonium chloride of the above-mentioned formula ratio of weighing, glycerol, lactic acid, menthol, Alumen, carbomer and Chinese medicine extract;
Step C, preparation: the load weighted benzalkonium chloride of step B, glycerol, lactic acid, menthol, Alumen, carbomer and Chinese medicine extract are put into container, add purified water and be settled to 1L;
Step D, filtration: the solution stirring of step C preparation is extremely even, namely get antibacterial gel;
Step e, packing, ethylene oxide sterilizing.
Preferably, in the described steps A addition of purified water be Radix Scutellariae, Cortex Phellodendri, Rhizoma Smilacis Glabrae, Semen Momordicae, Folium Artemisiae Argyi, Radix Sophorae Flavescentis, Fructus Cnidii, Cortex Dictamni cumulative volume 10-15 doubly, the temperature of refinement is 95-98 ℃, the time of refinement is 2-4h.
Preferably, described step e adopts the antibacterial gel angle of rake mode of packing into is carried out packing.
Described antibacterial gel is used for gynaecopathia or hemorrhoid.
The present invention compared with prior art, beneficial effect is:
(1) the present invention adopts benzalkonium chloride, glycerol, lactic acid, menthol, Alumen, carbomer and Chinese medicine extract to produce antibacterial gel, each raw material complements each other, bring into play the synergism of each stock yard, the multiple antiinflammatory that particularly contains in the Chinese medicine extract, antibiotic, analgesic composition make bacteriostasis property of the present invention reach the best, short treating period, instant effect.
(2) antibacterial gel biological compatibility of the present invention meets GB/T 16886.11-2011 requirement, and antibacterial gel microbiological indicator meets GB 15979-2002 requirement.
(3) the present invention is applicable to that various vaginal bacteria sexuality are dyed, the infusorian sexuality is dyed, leucorrhea, candidiasis sexuality dye, and control and the nursing of cervix uteri and reproductive tract and mucosa traumatic infection promote the healing of wound surface behind the cervical erosion naturopathy; Improve cross infections such as vaginal dryness, sexual life.Be applicable to control and nursing and anti-inflammatory analgesic etc. behind internal hemorrhoid, external hemorrhoid, mixed hemorrhoid, anal fissure, the anal-surgery.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment.
Embodiment 1.
A kind of antibacterial gel, every liter of antibacterial gel is made up of following raw material:
Benzalkonium chloride 1.7g, glycerol 30ml, menthol 0.1g, Alumen 1g, lactic acid 0.3g, carbomer 2.5g, Chinese medicine extract 3g, purified water surplus.Described Chinese medicine extract is formed by the raw material extraction of following weight portion: 10 parts of Radix Scutellariaes, 20 parts of Cortex Phellodendris, 20 parts of Rhizoma Smilacis Glabraes, 10 parts of Semen Momordicaes, 10 parts of Folium Artemisiae Argyis, 20 parts of Radix Sophorae Flavescentiss, 20 parts of Fructus Cnidiis, 10 parts of Cortex Dictamni.
A kind of preparation method of antibacterial gel, it comprises following preparation process:
The preparation of steps A, Chinese medicine extract: Radix Scutellariae, Cortex Phellodendri, Rhizoma Smilacis Glabrae, Semen Momordicae, Folium Artemisiae Argyi, Radix Sophorae Flavescentis, Fructus Cnidii, the Cortex Dictamni of above-mentioned formula ratio are added the purified water refinement, the addition of purified water is Radix Scutellariae, Cortex Phellodendri, Rhizoma Smilacis Glabrae, Semen Momordicae, Folium Artemisiae Argyi, Radix Sophorae Flavescentis, Fructus Cnidii, Cortex Dictamni cumulative volume 10 times, the temperature of refining is 95 ℃, the time of refining is 2h, cross leaching filtrate, concentrated, dry, obtain Chinese medicine extract;
Step B, weighing: the benzalkonium chloride of the above-mentioned formula ratio of weighing, glycerol, lactic acid, menthol, Alumen, carbomer and Chinese medicine extract;
Step C, preparation: the load weighted benzalkonium chloride of step B, glycerol, lactic acid, menthol, Alumen, carbomer and Chinese medicine extract are put into container, add purified water and be settled to 1L;
Step D, filtration: the solution stirring of step C preparation is extremely even, namely get antibacterial gel;
Step e, packing: adopt the antibacterial gel angle of rake mode of packing into is carried out packing, ethylene oxide sterilizing.
Embodiment 2.
A kind of antibacterial gel, every liter of antibacterial gel is made up of following raw material:
Benzalkonium chloride 1.8g, glycerol 40ml, menthol 0.5g, Alumen 1.5g, lactic acid 0.3g, carbomer 3.5g, Chinese medicine extract 4g, purified water surplus.Described Chinese medicine extract is formed by the raw material extraction of following weight portion: 20 parts of Radix Scutellariaes, 30 parts of Cortex Phellodendris, 30 parts of Rhizoma Smilacis Glabraes, 20 parts of Semen Momordicaes, 20 parts of Folium Artemisiae Argyis, 30 parts of Radix Sophorae Flavescentiss, 30 parts of Fructus Cnidiis, 20 parts of Cortex Dictamni.
A kind of preparation method of antibacterial gel, it comprises following preparation process:
The preparation of steps A, Chinese medicine extract: Radix Scutellariae, Cortex Phellodendri, Rhizoma Smilacis Glabrae, Semen Momordicae, Folium Artemisiae Argyi, Radix Sophorae Flavescentis, Fructus Cnidii, the Cortex Dictamni of above-mentioned formula ratio are added the purified water refinement, the addition of purified water is Radix Scutellariae, Cortex Phellodendri, Rhizoma Smilacis Glabrae, Semen Momordicae, Folium Artemisiae Argyi, Radix Sophorae Flavescentis, Fructus Cnidii, Cortex Dictamni cumulative volume 13 times, the temperature of refining is 96 ℃, the time of refining is 3h, cross leaching filtrate, concentrated, dry, obtain Chinese medicine extract;
Step B, weighing: the benzalkonium chloride of the above-mentioned formula ratio of weighing, glycerol, lactic acid, menthol, Alumen, carbomer and Chinese medicine extract;
Step C, preparation: the load weighted benzalkonium chloride of step B, glycerol, lactic acid, menthol, Alumen, carbomer and Chinese medicine extract are put into container, add purified water and be settled to 1L;
Step D, filtration: the solution stirring of step C preparation is extremely even, namely get antibacterial gel;
Step e, packing: adopt the antibacterial gel angle of rake mode of packing into is carried out packing, ethylene oxide sterilizing.
Embodiment 3.
A kind of antibacterial gel, every liter of antibacterial gel is made up of following raw material:
Benzalkonium chloride 1.9g, glycerol 50ml, menthol 1.3g, Alumen 1.8g, lactic acid 0.4g, carbomer 5g, Chinese medicine extract 6g, purified water surplus.Described Chinese medicine extract is formed by the raw material extraction of following weight portion: 20 parts of Radix Scutellariaes, 10 parts of Cortex Phellodendris, 10 parts of Rhizoma Smilacis Glabraes, 20 parts of Semen Momordicaes, 20 parts of Folium Artemisiae Argyis, 10 parts of Radix Sophorae Flavescentiss, 10 parts of Fructus Cnidiis, 20 parts of Cortex Dictamni.
A kind of preparation method of antibacterial gel, it comprises following preparation process:
The preparation of steps A, Chinese medicine extract: Radix Scutellariae, Cortex Phellodendri, Rhizoma Smilacis Glabrae, Semen Momordicae, Folium Artemisiae Argyi, Radix Sophorae Flavescentis, Fructus Cnidii, the Cortex Dictamni of above-mentioned formula ratio are added the purified water refinement, the addition of purified water is Radix Scutellariae, Cortex Phellodendri, Rhizoma Smilacis Glabrae, Semen Momordicae, Folium Artemisiae Argyi, Radix Sophorae Flavescentis, Fructus Cnidii, Cortex Dictamni cumulative volume 15 times, the temperature of refining is 98 ℃, the time of refining is 4h, cross leaching filtrate, concentrated, dry, obtain Chinese medicine extract;
Step B, weighing: the benzalkonium chloride of the above-mentioned formula ratio of weighing, glycerol, lactic acid, menthol, Alumen, carbomer and Chinese medicine extract;
Step C, preparation: the load weighted benzalkonium chloride of step B, glycerol, lactic acid, menthol, Alumen, carbomer and Chinese medicine extract are put into container, add purified water and be settled to 1L;
Step D, filtration: the solution stirring of step C preparation is extremely even, namely get antibacterial gel;
Step e, packing: adopt the antibacterial gel angle of rake mode of packing into is carried out packing, ethylene oxide sterilizing.
Embodiment 4.
A kind of antibacterial gel, every liter of antibacterial gel is made up of following raw material:
Benzalkonium chloride 1.9g, glycerol 30ml, menthol 1.1g, Alumen 1.2g, lactic acid 0.3g, carbomer 4g, Chinese medicine extract 5g, purified water surplus.Described Chinese medicine extract is formed by the raw material extraction of following weight portion: 30 parts of Radix Scutellariaes, 20 parts of Cortex Phellodendris, 20 parts of Rhizoma Smilacis Glabraes, 30 parts of Semen Momordicaes, 30 parts of Folium Artemisiae Argyis, 20 parts of Radix Sophorae Flavescentiss, 20 parts of Fructus Cnidiis, 30 parts of Cortex Dictamni.
A kind of preparation method of antibacterial gel, it comprises following preparation process:
The preparation of steps A, Chinese medicine extract: Radix Scutellariae, Cortex Phellodendri, Rhizoma Smilacis Glabrae, Semen Momordicae, Folium Artemisiae Argyi, Radix Sophorae Flavescentis, Fructus Cnidii, the Cortex Dictamni of above-mentioned formula ratio are added the purified water refinement, the addition of purified water is Radix Scutellariae, Cortex Phellodendri, Rhizoma Smilacis Glabrae, Semen Momordicae, Folium Artemisiae Argyi, Radix Sophorae Flavescentis, Fructus Cnidii, Cortex Dictamni cumulative volume 12 times, the temperature of refining is 97 ℃, the time of refining is 4h, cross leaching filtrate, concentrated, dry, obtain Chinese medicine extract;
Step B, weighing: the benzalkonium chloride of the above-mentioned formula ratio of weighing, glycerol, lactic acid, menthol, Alumen, carbomer and Chinese medicine extract;
Step C, preparation: the load weighted benzalkonium chloride of step B, glycerol, lactic acid, menthol, Alumen, carbomer and Chinese medicine extract are put into container, add purified water and be settled to 1L;
Step D, filtration: the solution stirring of step C preparation is extremely even, namely get antibacterial gel;
Step e, packing: adopt the antibacterial gel angle of rake mode of packing into is carried out packing, ethylene oxide sterilizing.
Dongguan gynecological of hospital carries out in the follow-up investigation among 100 patients to the antibacterial gel of employing the present invention, and 60 patients' recoveries from illness do not have recurrence in two years, and 37 patient's symptoms alleviate greatly, and total effective rate of the present invention is up to 97%.
Anorectal section of Guangxi hospital carries out in the follow-up investigation among 200 patients to the antibacterial gel of employing the present invention, and 140 patients' recoveries from illness do not have recurrence in two years, and 56 patient's symptoms alleviate greatly, and total effective rate of the present invention is up to 98%.
Concrete checking example 1.
Wu, the man, 46 years old, because prolonged constipation causes external hemorrhoid, though not very serious, again and again outbreak always, the antibacterial gel of the embodiment of the invention 1 is adopted in the back, pushes 12ml with propeller just before going to bed every night, recovery from illness after two months, not recurrence in 4 years.
Concrete checking example 2.
Xue, the woman, 30 years old, since son back leucorrhoea grow in quantity is given birth in pregnancy, she selects some washing liquids and gel for use, but does not see that always any curative effect is arranged, and the antibacterial gel of the embodiment of the invention 2 is adopted in the back, push 10ml with propeller just before going to bed every night, the leucorrhoea grow in quantity phenomenon disappears after 10 days, not recurrence in 3 years.
Concrete checking example 3.
What certain, man, 33 years old, because the work reason is sitting in by the computer desk for a long time, owing to the internal hemorrhoid that lacks exercise, though treatment is arranged, but again and again outbreak always, when serious, haemophilia, the antibacterial gel of the embodiment of the invention 3 is adopted in the back, push 15ml with propeller just before going to bed every night, internal hemorrhoid disappears substantially behind the two weeks, recovery from illness after two months, not recurrence in two years.
Concrete checking example 4.
The Wang, woman, 26 years old, because not noticing that Personal hygiene got the infusorian sexuality and dyes, she ate oral medicine, and curative effect is very poor, after select some washing liquids and gel for use, but one stop using, vaginitis will show effect, the antibacterial gel of the embodiment of the invention 4 is adopted in the back, push 20ml with propeller just before going to bed every night, stop using behind the two weeks, remove examination in hospital after one month, the infusorian sexuality is dyed symptom and is all disappeared, in two years not recurrence.
Should be noted that at last; above embodiment is only in order to illustrate technical scheme of the present invention; but not limiting the scope of the invention; although with reference to preferred embodiment the present invention has been done to explain; those of ordinary skill in the art is to be understood that; can make amendment or be equal to replacement technical scheme of the present invention, and not break away from essence and the scope of technical solution of the present invention.
Claims (10)
1. antibacterial gel, it is characterized in that: every liter of antibacterial gel is made up of following raw material:
Benzalkonium chloride 1.7-1.9g
Glycerol 30-50ml
Menthol 0.1-1.3g
Alumen 1-1.8g
Lactic acid 0.3-0.4g
Carbomer 2.5-5g
Chinese medicine extract 3-6g
The purified water surplus.
2. a kind of antibacterial gel according to claim 1, it is characterized in that: every liter of antibacterial gel is made up of following raw material:
Benzalkonium chloride 1.8-1.9g
Glycerol 40-50ml
Menthol 0.5-1.3g
Alumen 1.5-1.8g
Lactic acid 0.3-0.4g
Carbomer 3.5-5g
Chinese medicine extract 4-6g
The purified water surplus.
3. a kind of antibacterial gel according to claim 1, it is characterized in that: every liter of antibacterial gel is made up of following raw material:
Benzalkonium chloride 1.8g
Glycerol 40ml
Menthol 0.5g
Alumen 1.5g
Lactic acid 0.3g
Carbomer 3.5g
Chinese medicine extract 4g
The purified water surplus.
4. a kind of antibacterial gel according to claim 1 is characterized in that: described Chinese medicine extract is extracted by the raw material of following weight portion and forms:
Radix Scutellariae 10-30 part
Cortex Phellodendri 10-30 part
Rhizoma Smilacis Glabrae 10-30 part
Semen Momordicae 10-30 part
Folium Artemisiae Argyi 10-30 part
Radix Sophorae Flavescentis 10-30 part
Fructus Cnidii 10-30 part
Cortex Dictamni 10-30 part.
5. a kind of antibacterial gel according to claim 4 is characterized in that: described Chinese medicine extract is extracted by the raw material of following weight portion and forms:
Radix Scutellariae 10-20 part
Cortex Phellodendri 20-30 part
Rhizoma Smilacis Glabrae 20-30 part
Semen Momordicae 10-20 part
Folium Artemisiae Argyi 10-20 part
Radix Sophorae Flavescentis 20-30 part
Fructus Cnidii 20-30 part
Cortex Dictamni 10-20 part.
6. a kind of antibacterial gel according to claim 4 is characterized in that: described Chinese medicine extract is extracted by the raw material of following weight portion and forms:
Radix Scutellariae 20-30 part
Cortex Phellodendri 10-20 part
Rhizoma Smilacis Glabrae 10-20 part
Semen Momordicae 20-30 part
Folium Artemisiae Argyi 20-30 part
Radix Sophorae Flavescentis 10-20 part
Fructus Cnidii 10-20 part
Cortex Dictamni 20-30 part.
7. the preparation method of the described a kind of antibacterial gel of claim 4, it is characterized in that: it comprises following preparation process:
The preparation of steps A, Chinese medicine extract: Radix Scutellariae, Cortex Phellodendri, Rhizoma Smilacis Glabrae, Semen Momordicae, Folium Artemisiae Argyi, Radix Sophorae Flavescentis, Fructus Cnidii, the Cortex Dictamni of above-mentioned formula ratio are added the purified water refinement, cross leaching filtrate, concentrated, dry, obtain Chinese medicine extract;
Step B, weighing: the benzalkonium chloride of the above-mentioned formula ratio of weighing, glycerol, lactic acid, menthol, Alumen, carbomer and Chinese medicine extract;
Step C, preparation: the load weighted benzalkonium chloride of step B, glycerol, lactic acid, menthol, Alumen, carbomer and Chinese medicine extract are put into container, add purified water and be settled to 1L;
Step D, filtration: the solution stirring of step C preparation is extremely even, namely get antibacterial gel;
Step e, packing, ethylene oxide sterilizing.
8. the preparation method of a kind of antibacterial gel according to claim 7, it is characterized in that: in the described steps A addition of purified water be Radix Scutellariae, Cortex Phellodendri, Rhizoma Smilacis Glabrae, Semen Momordicae, Folium Artemisiae Argyi, Radix Sophorae Flavescentis, Fructus Cnidii, Cortex Dictamni cumulative volume 10-15 doubly, the temperature of refining is 95-98 ℃, and the time of refinement is 2-4h.
9. the preparation method of a kind of antibacterial gel according to claim 7 is characterized in that: described step e adopts carries out packing with the antibacterial gel angle of rake mode of packing into.
10. the purposes of the described a kind of antibacterial gel of claim 1, it is characterized in that: described antibacterial gel has following purposes: be used for that various vaginal bacteria sexuality are dyed, the infusorian sexuality is dyed, leucorrhea, candidiasis sexuality dye control and the nursing of cervix uteri and reproductive tract and mucosa traumatic infection; Be used for improving vaginal dryness, sexual life cross infection; For control and nursing and the anti-inflammatory analgesic behind internal hemorrhoid, external hemorrhoid, mixed hemorrhoid, anal fissure, the anal-surgery.
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| CN103920072A (en) * | 2014-04-16 | 2014-07-16 | 广西信业生物技术有限公司 | Chitosan antibacterial gel and preparation method thereof |
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| CN105012994A (en) * | 2015-08-25 | 2015-11-04 | 东莞市达庆医疗器械有限公司 | Medical, functional and biological hydrogel dressing for urinary system and preparation method of hydrogel dressing |
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| CN109044928A (en) * | 2018-09-05 | 2018-12-21 | 广州丽彦妆生物科技有限公司 | A kind of secret nursing bacteriostatic gel and preparation method thereof |
| CN109316634A (en) * | 2018-10-23 | 2019-02-12 | 江苏耐雀生物工程技术有限公司 | A kind of natural bacteriostatic midwifery gel and preparation method thereof |
| CN110193051A (en) * | 2019-06-12 | 2019-09-03 | 广州梅彭健康科技有限公司 | Bacteriostatic gel and preparation method thereof |
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| CN112472772A (en) * | 2020-12-14 | 2021-03-12 | 江西长通实业有限公司 | Antibacterial gel and preparation method thereof |
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