CN103260637B - 乙酰肝素n-硫酸酯酶cns递送的方法和组合物 - Google Patents

乙酰肝素n-硫酸酯酶cns递送的方法和组合物 Download PDF

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CN103260637B
CN103260637B CN201180040902.2A CN201180040902A CN103260637B CN 103260637 B CN103260637 B CN 103260637B CN 201180040902 A CN201180040902 A CN 201180040902A CN 103260637 B CN103260637 B CN 103260637B
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concentration
purposes
hns
protein
stabilization formulations
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CN103260637A (zh
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F·纳托里
G·朱
J·特略
Y·江
J·宗
Z·夏若克
B·维纳格利亚
J·潘
R·菲佛
P·加莱斯
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Shire Human Genetics Therapies Inc
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Shire Human Genetics Therapies Inc
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
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    • C12Y310/01001—N-Sulfoglucosamine sulfohydrolase (3.10.1.1)
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CN201180040902.2A 2010-06-25 2011-06-25 乙酰肝素n-硫酸酯酶cns递送的方法和组合物 Expired - Fee Related CN103260637B (zh)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US35885710P 2010-06-25 2010-06-25
US61/358,857 2010-06-25
US36078610P 2010-07-01 2010-07-01
US61/360,786 2010-07-01
US38786210P 2010-09-29 2010-09-29
US61/387,862 2010-09-29
US201161435710P 2011-01-24 2011-01-24
US61/435,710 2011-01-24
US201161442115P 2011-02-11 2011-02-11
US61/442,115 2011-02-11
US201161476210P 2011-04-15 2011-04-15
US61/476,210 2011-04-15
US201161495268P 2011-06-09 2011-06-09
US61/495,268 2011-06-09
PCT/US2011/041922 WO2011163647A2 (en) 2010-06-25 2011-06-25 Methods and compositions for cns delivery of heparan n-sulfatase

Related Child Applications (1)

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CN201610086722.2A Division CN105664142A (zh) 2010-06-25 2011-06-25 乙酰肝素n-硫酸酯酶cns递送的方法和组合物

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CN103260637A CN103260637A (zh) 2013-08-21
CN103260637B true CN103260637B (zh) 2016-04-06

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US (1) US9320711B2 (https=)
EP (1) EP2588131B1 (https=)
JP (1) JP6073783B2 (https=)
KR (1) KR20140005842A (https=)
CN (1) CN103260637B (https=)
AU (2) AU2011270667B2 (https=)
BR (1) BR112012033197A2 (https=)
CA (1) CA2805413A1 (https=)
MX (1) MX2013000320A (https=)
NZ (1) NZ605874A (https=)
RU (1) RU2012154576A (https=)
TW (1) TWI546078B (https=)
WO (1) WO2011163647A2 (https=)

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