CN103251054A - Anti-fatigue health protection food composition and preparation method thereof - Google Patents
Anti-fatigue health protection food composition and preparation method thereof Download PDFInfo
- Publication number
- CN103251054A CN103251054A CN2013102097492A CN201310209749A CN103251054A CN 103251054 A CN103251054 A CN 103251054A CN 2013102097492 A CN2013102097492 A CN 2013102097492A CN 201310209749 A CN201310209749 A CN 201310209749A CN 103251054 A CN103251054 A CN 103251054A
- Authority
- CN
- China
- Prior art keywords
- extract
- fatigue
- vitamin
- guarana
- astragalus root
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to an anti-fatigue health protection food composition and a preparation method thereof. The anti-fatigue health protection food composition comprises the following materials in percentage by weight: 20-35 percent of a rhodiola extract, 10-20 percent of a guarana extract, 10-20 percent of an astragalus extract, 3-5 percent of vitamin C, 3-5 percent of vitamin E, 2-5 percent of nicotinic acid and the balance of edible auxiliary materials. On the basis of a fatigue generation mechanism and with combination of modern pharmacological research results, the rhodiola extract, the guarana extract and the astragalus extract are taken as the main raw materials for timely supplementing the consumption of internal energy substances, quickly resisting fatigue and recovering strength, reliving brain fatigue and improving the durability and the working efficiency in a fatigue state. By the reducing nutritious substances, such as the vitamin C and the vitamin E, the radical level and the oxidization stress reaction in vivo in the fatigue state are reduced and alleviated, the fatigue can be effectively alleviated, and the anti-fatigue health protection effect is enhanced.
Description
Technical field
The present invention relates to a kind of composition and method of making the same, relate in particular to a kind of mechanism that takes place based on fatigue, in conjunction with the modern pharmacological research achievement, select the natural products of integration of drinking and medicinal herbs for use, effective extract based on rhodiola root, guarana and the Radix Astragali, nontoxic to human body, can be used as the long-term practical fatigue resistant health food composition and method of making the same of health food.
Background technology
Fatigue is a kind of sub-health state of the people's of having a strong impact on quality of life, and fatigue causes disease, the tired existing final conclusion of work capacity, operating efficiency and study effect that reduces.Since the human fatigue of Mosso (Moso) research in 1880 begins, have the history in more than 100 year both at home and abroad about the physiological Study of organism fatigue (fatigue).Chronic fatigue syndrome (chronic fatigue syndrome, CFS) by U.S. CDC (CDC) in definite designation in 1988, be defined as and " a kind ofly show as main syndrome so that fatigue, conscious heating, sore-throat, myalgia, arthralgia, headache, difficult concentrating, poor memory, sleep-disorder and depression etc. are non-specific, and set up the CDC diagnostic criteria.Fukuda improved definition in 1994, and had formed the 1994CDC diagnostic criteria.
The relevant tired domestic and international scientist of mechanism carried out many researchs from each ambit, and set up many hypothesis.Protectiveness inhibition theory as Pavlov thinks no matter be physical fatigue or mental fatigue, all be the result that the cerebral cortex protectiveness holds back the development, think that cerebral cortex is in a kind of fever state in high strength or the process that works long hours, the brain cell working strength obviously increases when quiet, cerebral cortex cell work ability is descended, in order to prevent the further consume of brain cell, cerebral cortex transfers inhibition to by excitatory state, and this inhibition is protectiveness and suppresses; Harvard University's fatigue study homeostasis sexual maladjustment theory think that fatigue is because pH value descends, water and salt metabolic disturbance causes with factor such as plasma osmolarity change; The energy exhaustion theory of Syed think tired generation mainly be since in the motion process in the body energy substance consume in a large number and can not get in time replenishing, and exercise intensity, asynchronism(-nization), the energy substance of consumption is also inequality, produces different exercise induced fatigues; Oxygen radical and the peroxidatic reaction of lipid that causes thereof strengthen that theory is thought oxygen radical and the peroxidatic reaction of lipid that causes can attack cells and other biological film such as mitochondria, cause ion and energetic supersession disorder, thereby cause exercise induced fatigue.Though these viewpoints have limitation, yet the support that still obtains many experiments in modern physiology research is considered to illustrate tired machine-processed basis with additional.
There are 5,000 years traditional Chinese medicine cultural advantages in China, utilize aspect the medicine-food two-purpose natural plants richly endowed by nature especially.Mechanism and nutritional intervention thereof for all kinds of fatigues, foreign study is many, domestic more, all kinds of nutritional agents emerge in an endless stream especially, but the research of the health products of nutritional supplementation still lacks to utilize the different fatigue generation mechanism to carry out targetedly at present, if utilize the different angles of tired mechanism, it is composite to adopt targetedly the antifatigue product to make up, and then is expected to improve greatly the effect of antifatigue.
The objective of the invention is to utilize domestic and international antifatigue plant to prepare its extract, in conjunction with the former studies achievement, provide a kind of and can faster alleviate tired health-care food composition and preparation method thereof.
The present invention is directed to the tired Mechanism Study that takes place, employing has the natural products of different antifatigue effects and makes effective fatigue preparations after composite, write articles at " Nutrition " as Gramiqnano professor 2006 and to point out, can effectively lessen fatigue by reducing response to oxidative stress, and obtain the checking of a large amount of experimental evidences; Utilize natural products such as caffeine can improve corticocerebral excitability, the generation of physical fatigue and mental fatigue is removed in the consumption of energy substance in time replenishing; Some have natural products such as the astragalus polyose that improves immunocompetence, can effectively alleviate the symptoms such as homeostasis sexual maladjustment that fatigue causes.Numerous literature research show that rhodiola root, the Radix Astragali, genseng, wilsonii etc. are all to be the plants with more definite antifatigue effectiveness.We find also that in early-stage Study the nutritional preparation intervention of combinations such as vitamin C, vitamin E, nicotinic acid can improve the working memory level of the compound sleep-deprived rat of psychological stress, the swimming with a load attached to the body time that can prolong rats.
Rhodiola root is the perennial meat herbaceous plant of Crassulaceae rhodiola, mainly originates in the high and cold mountain area on ground such as Tibet, Xinjiang, Qinghai, Gansu, northeast, and wherein the rhodiola kirilowii Regel with Tibet is top grade.The medicinal extract of Soviet Union's report Rhodida plant has the strong effect of intelligence development, can be as the medication of antifatigue and treatment nervous function disease.Brekgman school thinks that Rhodida plant has good adaptation former state effect, and human body is had special regulating action, and the ill mark sense normal condition that the different causes of disease are caused transforms.When Kangxu Supreme Being fights west, once took this thing to eliminate army's fatigue.Document is put down in writing it and can be strengthened the body resistance to consolidate the constitution, can be clearing heat and detoxicating, and detumescence is used for the treatment of warm disease, and lung heat is poisoned and limb edema.The modern biomedical experiment shows, the effect that rhodiola root has antifatigue, anti-anoxic, resisting microwave radiation, raising immunity, adjusting nervous function, stimulating central nervous system, inhibition growth of tumour cell and prevents and treats angiocardiopathy, diabetes, and rhodiola root is without any side effects and habituation.
Brazil's rain forest plant guarana (Guarana) be a kind of natural caffeine that contains than the antifatigue plant of horn of plenty, but its effect not exclusively is equal to caffeine, almost therefore caffeine-free habituation also is the favorite antifatigue food of Brazilian.Except containing natural caffeine, the guarana extract also contains theophylline, theobromine, tannin, Chinese honey locust alkali, multiple catechol and other micro substances.Can be used for the raising of memory, promoting circulation of blood, convergence, prevention fat form and reduce fat, repair by cell and destroyed and antioxidation by the DNA that nitrite causes.Still rarely report the application of guarana antifatigue is at present domestic.
The Radix Astragali is successive dynasties traditional tonic medicines commonly used, and the dry root for legume Astragalus membranacus or astragalus mongolicus has tonifying middle-Jiao and Qi, an effect of the apocenosis of drawing out pus by applying a plaster to the affected part, expelling pus and promoting granulation and raising immunity.
Summary of the invention
At the problems referred to above, main purpose of the present invention is to provide a kind of mechanism that takes place based on fatigue, in conjunction with the modern pharmacological research achievement, select the natural products of integration of drinking and medicinal herbs for use, effective extract based on rhodiola root, guarana and the Radix Astragali, nontoxic to human body, can be used as the long-term practical fatigue resistant health food composition and method of making the same of health food.
The present invention solves above-mentioned technical problem by following technical proposals: a kind of fatigue resistant health food composition, described composition comprise gadol extract, guarana extract, Astragalus Root P.E, vitamin C, vitamin E, nicotinic acid and edible auxiliary materials; Wherein between 20%-35%, 10%-20%, 10-20%, 3%-5%, 3%-5% and 2%-5%, surplus be edible auxiliary materials to the shared part by weight of gadol extract, guarana extract, Astragalus Root P.E, vitamin C, vitamin E and nicotinic acid respectively.
In specific embodiments of the invention, the mass percentage content of the mass percentage content of the mass percentage content of rhodioside caffeine more than or equal to 3%, in guarana extract astragalus polyose and total saponin(e more than or equal to 8%, in the Astragalus Root P.E is more than or equal to 35% in the described gadol extract.
In specific embodiments of the invention, described edible auxiliary materials is one or more combinations in disintegrant, filler, sweetener and the lubricant of pharmaceutically using always.
A kind of method for preparing above-mentioned composition, described method comprises the steps: to adopt water extraction to prepare gadol extract, guarana extract and Astragalus Root P.E respectively, then gadol extract, guarana extract, Astragalus Root P.E and vitamin C, vitamin E, nicotinic acid and the edible auxiliary materials that obtains mixed by formula rate, wet granulation, dry below 60 ℃, conventional method is prepared into solid pharmaceutical preparation.
In specific embodiments of the invention, described gadol extract, guarana extract and Astragalus Root P.E adopt noodle producing method down:
After block rhodiola root, guarana and astragalus root cleaned up respectively, drying is pulverized, and sieving makes fine powder separately, every kind of fine powder adds 3 times of dose water at every turn or ethanol water decocts 2-3 time, each 2 hours, filter, the slow fire heating evaporation is concentrated into quantitatively, transfer pH value of solution to 4-5 with hydrochloric acid, the gelatin precipitation method are settled out tannin from aqueous extract, with the filtrate spray-drying that obtains, obtain dry gadol extract, guarana extract and Astragalus Root P.E respectively.
In specific embodiments of the invention, the solid pharmaceutical preparation that is prepared into is capsule, electuary or tablet.
Positive progressive effect of the present invention is: the present invention and common fatigue resistant health food compare, the present invention is the mechanism that takes place based on fatigue, in conjunction with the modern pharmacological research achievement, select the natural products of integration of drinking and medicinal herbs for use, based on the effective extract of rhodiola root, guarana and the Radix Astragali, the consumption of energy substance in time replenishing, quick antifatigue, regain one's strength rapidly, alleviate mental fatigue, improve endurance and operating efficiency under the frazzle.In conjunction with reproducibility thing nutriments such as vitamin C, vitamin Es, reduce free radical level and response to oxidative stress in the fatigue state lower body, effectively lessen fatigue, strengthen the anti-fatigue health-caring effect.
The specific embodiment
Provide preferred embodiment of the present invention below in conjunction with specific embodiment, to describe technical scheme of the present invention in detail.
Embodiment 1
1, the preparation method of rhodiola root, guarana and Astragalus Root P.E: after block rhodiola root, guarana and astragalus root cleaned up respectively, drying was pulverized, and sieving makes fine powder separately.Various fine powders add 3 times of dose decoctings respectively at every turn and boil 2-3 time, each 2 hours, the extract that merging is filtered through the preliminary normal pressure of 200 order filter clothes, airtight leaving standstill 24 hours, inclining supernatant, and 400 order filter cloth normal pressures remove by filter precipitation, the slow fire heating evaporation is concentrated into quantitatively, transfer pH value of solution to 4-5 with hydrochloric acid, the gelatin precipitation method are settled out tannin from aqueous extract, and normal pressure removes by filter precipitation.With the filtrate spray-drying that obtains, respectively dry gadol extract, guarana extract and Astragalus Root P.E.
2, method of granulating: gadol extract 25g, guarana extract 15g, Astragalus Root P.E 15g, vitamin C 5g, nicotinic acid 2g and pharmaceutic adjuvant filler microcrystalline cellulose 22g, disintegrant PVPP 10g, mix by above-mentioned formula rate respectively, be sprayed on medical surfaces after the vitamin E of 5g oily is dissolved in 95% ethanol, wet granulation, dry below 60 ℃
3, above granulation desciccate is got final product with the conventional method capsule charge.
Embodiment 2
1, the preparation method of rhodiola root, guarana and Astragalus Root P.E: after block rhodiola root, guarana and astragalus root cleaned up respectively, drying was pulverized, and sieving makes fine powder separately.Various fine powders add 3 times of dose decoctings respectively at every turn and boil 2-3 time, each 2 hours, the extract that merging is filtered through the preliminary normal pressure of 200 order filter clothes, airtight leaving standstill 24 hours, inclining supernatant, and 400 order filter cloth normal pressures remove by filter precipitation, the slow fire heating evaporation is concentrated into quantitatively, transfer pH value of solution to 4-5 with hydrochloric acid, the gelatin precipitation method are settled out tannin from aqueous extract, and normal pressure removes by filter precipitation.With the filtrate spray-drying that obtains, respectively dry gadol extract, guarana extract and Astragalus Root P.E.
2, method of granulating: gadol extract 25g, guarana extract 15g, Astragalus Root P.E 15g, vitamin C 5g, nicotinic acid 2g and pharmaceutic adjuvant filler microcrystalline cellulose 15g, disintegrant PVPP 8g, magnesium stearate lubricant 10g, mix by above-mentioned formula rate respectively, be sprayed on medical surfaces after the vitamin E of 5g oily is dissolved in 95% ethanol, wet granulation, dry below 60 ℃
3, above granulation desciccate being pressed into tablet with tablet press machine gets final product.
Embodiment 3
1, the preparation method of rhodiola root, guarana and Astragalus Root P.E: after block rhodiola root, guarana and astragalus root cleaned up respectively, drying was pulverized, and sieving makes fine powder separately.Various fine powders add 3 times of dose decoctings respectively at every turn and boil 2-3 time, each 2 hours, the extract that merging is filtered through the preliminary normal pressure of 200 order filter clothes, airtight leaving standstill 24 hours, inclining supernatant, and 400 order filter cloth normal pressures remove by filter precipitation, the slow fire heating evaporation is concentrated into quantitatively, transfer pH value of solution to 4-5 with hydrochloric acid, the gelatin precipitation method are settled out tannin from aqueous extract, and normal pressure removes by filter precipitation.With the filtrate spray-drying that obtains, respectively dry gadol extract, guarana extract and Astragalus Root P.E.
2, method of granulating: gadol extract 30g, guarana extract 15g, Astragalus Root P.E 15g, vitamin C 5g, nicotinic acid 2g and filler microcrystalline cellulose 22g, disintegrant PVPP 10g, mix by above-mentioned formula rate respectively, be sprayed on medical surfaces after the vitamin E of 5g oily is dissolved in 95% ethanol, wet granulation, dry below 60 ℃.
3, with the suitable damp-prrof packing of above granulation desciccate, be electuary.
Embodiment 4
1, the preparation method of rhodiola root, guarana and Astragalus Root P.E: after block rhodiola root, guarana and astragalus root cleaned up respectively, drying was pulverized, and sieving makes fine powder separately.Various fine powders add 3 times of dose 60% ethanol respectively at every turn and decoct 2-3 time, each 2 hours, the extract that merging is filtered through the preliminary normal pressure of 200 order filter clothes, airtight leaving standstill 24 hours, inclining supernatant, and 400 order filter cloth normal pressures remove by filter precipitation, the slow fire heating evaporation is concentrated into quantitatively, transfer pH value of solution to 4-5 with hydrochloric acid, the gelatin precipitation method are settled out tannin from extract, and normal pressure removes by filter precipitation.With the filtrate spray-drying that obtains, respectively dry gadol extract, guarana extract and Astragalus Root P.E.
2, method of granulating: gadol extract 30g, guarana extract 18g, Astragalus Root P.E 20g, vitamin C 5g, nicotinic acid 2g and pharmaceutic adjuvant filler microcrystalline cellulose 10g, disintegrant PVPP 10g, mix by above-mentioned formula rate respectively, be sprayed on medical surfaces after the vitamin E of 5g oily is dissolved in 95% ethanol, wet granulation, dry below 60 ℃.
3, with above granulation desciccate with the conventional method capsule charge.
In order better to verify anti-fatigue effect of the present invention, the present inventor has done following test, below is concrete experimentation and experiment effect.
To the composition of the present invention's preparation, the mouse swimming with a load attached to the body test through carrying out the antifatigue effect and the checking of pole-jump test, the result is as follows:
1, mouse swimming with a load attached to the body experiment
Kunming kind small white mouse, the cleaning level, male, body weight 19-21g is divided into administration group and negative control group at random, 10 every group.Administration group mouse is by per kilogram of body weight filling every day stomach present composition 0.3g, and the control group control-animal gives distilled water, and 0.5ml/1 time/day, continuous irrigation stomach 30 days.After last was irritated stomach 30min, the load sheet lead of 5% body weight of mouse tail was put into depth of water 30cm, and in the swimming case of water temperature (25 ± 1) ℃, record mouse to swimming begins to exhaust to power the time of (not emerging in 10 seconds), as the mouse swimming time.All data input SPSS10.0 statistical softwares relatively use T-test between group.The result shows that the swimming with a load attached to the body time that gives health composition group mouse significantly is longer than control group, and relatively there were significant differences (P＜0.05) between the two.Illustrate that the application of the present composition can prolong the swimming with a load attached to the body time of mouse.
2, mouse pole-climbing time test
Kunming kind small white mouse, the cleaning level, male, body weight 19-21g is divided into administration group and negative control group at random, 10 every group.Administration group mouse is by per kilogram of body weight filling every day stomach present composition 0.3g, and the control group control-animal gives distilled water, and 0.5ml/1 time/day, continuous irrigation stomach 30 days.It is the pole-climbing frame that used equipment is tested in pole-climbing, and pole-climbing frame specification is: diameter (0.8～1.0) cm, be about the lucite pole into 25cm, and the upper end is fixed on the plank, and the lower end is unsettled, about 20cm apart from ground.After last is irritated stomach 30min, mouse is placed on the perspex bar of pole-climbing frame, makes its muscle be in the static(al) tense situation, record since mouse muscle fatigue from time that rod falls, end experiment when dropping down for the third time, the experiment that accumulative total is three times is as the pole-climbing time.All data input SPSS10.0 statistical softwares relatively use T-test between group.The result shows that the pole-climbing time that gives health composition filling stomach group mouse significantly is longer than control group, and relatively there were significant differences (P＜0.05) between the two.Illustrate that the application of the present composition can prolong the pole-climbing time of mouse.
The present invention and common fatigue resistant health food compare, the present invention is the mechanism that takes place based on fatigue, in conjunction with the modern pharmacological research achievement, select the natural products of integration of drinking and medicinal herbs for use, with rhodiola root, the effective extract of guarana and the Radix Astragali is main, the consumption of energy substance in time replenishing, quick antifatigue, regain one's strength rapidly, alleviate mental fatigue, improve endurance and operating efficiency under the frazzle, in conjunction with vitamin C, reproducibility thing nutriments such as vitamin E, reduce free radical level and response to oxidative stress in the fatigue state lower body, effectively lessen fatigue, strengthen the anti-fatigue health-caring effect.
More than show and described basic principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; that describes in above-described embodiment and the specification just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications; these changes and improvements all fall in the claimed scope of the invention, and the claimed scope of the present invention is defined by appending claims and equivalent thereof.
Claims (6)
1. fatigue resistant health food composition, it is characterized in that: described composition comprises gadol extract, guarana extract, Astragalus Root P.E, vitamin C, vitamin E, nicotinic acid and edible auxiliary materials; Wherein between 20%-35%, 10%-20%, 10-20%, 3%-5%, 3%-5% and 2%-5%, surplus be edible auxiliary materials to the shared part by weight of gadol extract, guarana extract, Astragalus Root P.E, vitamin C, vitamin E and nicotinic acid respectively.
2. fatigue resistant health food composition according to claim 1 is characterized in that: the mass percentage content of the mass percentage content of the mass percentage content of rhodioside caffeine more than or equal to 3%, in guarana extract astragalus polyose and total saponin(e more than or equal to 8%, in the Astragalus Root P.E is more than or equal to 35% in the described gadol extract.
3. fatigue resistant health food composition according to claim 1 is characterized in that: described edible auxiliary materials is one or more combinations in disintegrant, filler, sweetener and the lubricant pharmaceutically commonly used.
4. method for compositions for preparing one of claim 1-3, it is characterized in that: described method comprises the steps: to adopt water extraction to prepare gadol extract, guarana extract and Astragalus Root P.E respectively, then gadol extract, guarana extract, Astragalus Root P.E and vitamin C, vitamin E, nicotinic acid and the edible auxiliary materials that obtains mixed by formula rate, wet granulation, dry below 60 ℃, conventional method is prepared into solid pharmaceutical preparation.
5. method according to claim 4 is characterized in that: described gadol extract, guarana extract and Astragalus Root P.E adopt noodle producing method down:
After block rhodiola root, guarana and astragalus root cleaned up respectively, drying is pulverized, and sieving makes fine powder separately, every kind of fine powder adds 3 times of dose water at every turn or ethanol water decocts 2-3 time, each 2 hours, filter, the slow fire heating evaporation is concentrated into quantitatively, transfer pH value of solution to 4-5 with hydrochloric acid, the gelatin precipitation method are settled out tannin from aqueous extract, with the filtrate spray-drying that obtains, obtain dry gadol extract, guarana extract and Astragalus Root P.E respectively.
6. method according to claim 4, it is characterized in that: the solid pharmaceutical preparation that is prepared into is capsule, electuary or tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310209749.2A CN103251054B (en) | 2013-05-31 | 2013-05-31 | Anti-fatigue health protection food composition and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310209749.2A CN103251054B (en) | 2013-05-31 | 2013-05-31 | Anti-fatigue health protection food composition and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103251054A true CN103251054A (en) | 2013-08-21 |
| CN103251054B CN103251054B (en) | 2015-04-22 |
Family
ID=48955565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310209749.2A Expired - Fee Related CN103251054B (en) | 2013-05-31 | 2013-05-31 | Anti-fatigue health protection food composition and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103251054B (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103977056A (en) * | 2014-05-14 | 2014-08-13 | 凌春生 | Compound rhodiola rosea chewing tablet and preparing method thereof |
| CN104799270A (en) * | 2014-01-26 | 2015-07-29 | 天津中瑞药业股份有限公司 | Capsule containing Radix Astragali and inositol nicotinate food nutritive fortifier |
| CN104799299A (en) * | 2014-01-26 | 2015-07-29 | 天津中瑞药业股份有限公司 | Preparation method of food nutritive fortifier containing Radix Astragali and inositol nicotinate |
| CN105360798A (en) * | 2015-01-29 | 2016-03-02 | 华中科技大学 | Maca formula capable of strengthening tolerance and explosive force and preparation method thereof |
| CN105918718A (en) * | 2016-04-27 | 2016-09-07 | 青海华实科技投资管理有限公司 | Chinese wolfberry fruit-rhodiola rosea oral liquid and preparation method thereof |
| CN106954854A (en) * | 2017-04-05 | 2017-07-18 | 大连丹特生物技术有限公司 | It is a kind of that there is composition of protection eyesight fatigue-relieving function and its preparation method and application |
| CN108056461A (en) * | 2017-12-10 | 2018-05-22 | 牡丹江师范学院 | A kind of black fungus ease constipation function chewable tablets and preparation method thereof |
| CN108541912A (en) * | 2018-04-13 | 2018-09-18 | 浙江依思味生物科技有限公司 | A kind of anti-oxidant blood-fat reducing composition and its preparation method and application |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101474309A (en) * | 2009-01-22 | 2009-07-08 | 中国人民解放军海军医学研究所 | Composition with anti-fatigue and anti-anoxia functions and preparation method thereof |
| CN102334689A (en) * | 2011-10-10 | 2012-02-01 | 中国人民解放军军事医学科学院卫生学环境医学研究所 | Composite nutrient capable of improving physical ability of human body |
| CN102349941A (en) * | 2011-10-19 | 2012-02-15 | 石家庄藏诺生物科技有限公司 | Traditional Chinese medicine composition for relieving fatigue and improving anoxia endurance and preparation method thereof |
-
2013
- 2013-05-31 CN CN201310209749.2A patent/CN103251054B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101474309A (en) * | 2009-01-22 | 2009-07-08 | 中国人民解放军海军医学研究所 | Composition with anti-fatigue and anti-anoxia functions and preparation method thereof |
| CN102334689A (en) * | 2011-10-10 | 2012-02-01 | 中国人民解放军军事医学科学院卫生学环境医学研究所 | Composite nutrient capable of improving physical ability of human body |
| CN102349941A (en) * | 2011-10-19 | 2012-02-15 | 石家庄藏诺生物科技有限公司 | Traditional Chinese medicine composition for relieving fatigue and improving anoxia endurance and preparation method thereof |
Non-Patent Citations (3)
| Title |
|---|
| D.O.KENNEDY: "Improved cognitive performance and mental fatigue following a multi-vitamin and mineral supplement with added guarana"( Paullinia cupana)", 《APPETITE》, 30 October 2008 (2008-10-30) * |
| 张颖捷等: "国内外抗疲劳研究进展", 《实用预防医学》, vol. 19, no. 7, 31 July 2012 (2012-07-31), pages 1112 - 1116 * |
| 郑哲君等: "抗疲劳功能食品的研究进展", 《食品科技》, no. 02, 20 February 2006 (2006-02-20) * |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104799270A (en) * | 2014-01-26 | 2015-07-29 | 天津中瑞药业股份有限公司 | Capsule containing Radix Astragali and inositol nicotinate food nutritive fortifier |
| CN104799299A (en) * | 2014-01-26 | 2015-07-29 | 天津中瑞药业股份有限公司 | Preparation method of food nutritive fortifier containing Radix Astragali and inositol nicotinate |
| CN103977056A (en) * | 2014-05-14 | 2014-08-13 | 凌春生 | Compound rhodiola rosea chewing tablet and preparing method thereof |
| CN105360798A (en) * | 2015-01-29 | 2016-03-02 | 华中科技大学 | Maca formula capable of strengthening tolerance and explosive force and preparation method thereof |
| CN105360798B (en) * | 2015-01-29 | 2018-11-16 | 华中科技大学 | A kind of enhancing endurance and the maca prescription of explosive force and preparation method thereof |
| CN105918718A (en) * | 2016-04-27 | 2016-09-07 | 青海华实科技投资管理有限公司 | Chinese wolfberry fruit-rhodiola rosea oral liquid and preparation method thereof |
| CN106954854A (en) * | 2017-04-05 | 2017-07-18 | 大连丹特生物技术有限公司 | It is a kind of that there is composition of protection eyesight fatigue-relieving function and its preparation method and application |
| CN108056461A (en) * | 2017-12-10 | 2018-05-22 | 牡丹江师范学院 | A kind of black fungus ease constipation function chewable tablets and preparation method thereof |
| CN108056461B (en) * | 2017-12-10 | 2021-04-30 | 牡丹江师范学院 | Black fungus chewable tablet with intestine moistening function and preparation method thereof |
| CN108541912A (en) * | 2018-04-13 | 2018-09-18 | 浙江依思味生物科技有限公司 | A kind of anti-oxidant blood-fat reducing composition and its preparation method and application |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103251054B (en) | 2015-04-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103251054B (en) | Anti-fatigue health protection food composition and preparation method thereof | |
| CN102960810B (en) | Maca beverage | |
| CN103877263B (en) | A kind of antifatigue health preparation of the compound Chinese medicine such as red ginseng, maca, green-tea extract (theanine) | |
| CN1314422C (en) | Shiweifuzheng medicine for tonifying qi and blood, warning yang and strengthening spleen and its prepn process | |
| CN105368669A (en) | Raw materials for health care wine capable of resisting fatigue and improving immunity and health care wine preparation method | |
| CN102115707A (en) | Health wine and preparation process thereof | |
| CN1596914A (en) | Medicine for treating eye disease caused by visceral disease | |
| CN101053621B (en) | Traditional Chinese medicinal composition for treating obesity and its preparation method | |
| CN102813693A (en) | Novel composite and preparation method and application thereof | |
| CN101147586B (en) | Health-care food for improving sleep | |
| CN102626463A (en) | Natural medicine compound for increasing bone mineral density and preventing and treating osteoporosis | |
| CN101919924B (en) | Pharmaceutical composition for curing tristimania and preparation method and application thereof | |
| CN112494569B (en) | Traditional Chinese medicine composition for improving immunity and preparation method and application thereof | |
| CN102784230B (en) | Pharmaceutical composition preparation for treating nutritional anemia | |
| CN106177166A (en) | A kind of compositions with function of physical fatigue alleviation and preparation method thereof | |
| CN116173177A (en) | Pharmaceutical composition for continuously improving male sexual function and preparation method thereof | |
| CN105361171B (en) | One kind having composition for relieving physical fatigue | |
| CN112641100A (en) | Anti-depression electuary containing folic acid | |
| CN102600231A (en) | Anti-fatigue nutrient and preparation method thereof | |
| CN106581443B (en) | Traditional Chinese medicine composition for preventing or treating military stress disorder and preparation method thereof | |
| CN105232675B (en) | A kind of Chinese veterinary medicinal composition and preparation method, purposes improving Stock genetics and breeding | |
| CN1301070C (en) | Heath-caring product having protecting function for chemical liver injury | |
| CN112791166B (en) | Medicinal and edible composition for enhancing muscle performance and relieving exercise-induced fatigue | |
| CN102172384A (en) | Chinese medicinal preparation with effects of resisting fatigue and enhancing immunity | |
| CN103860761A (en) | Pharmaceutical composition with effects of improving immunity and resisting fatigue as well as preparation method and application of pharmaceutical composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150422 Termination date: 20160531 |