CN1301070C - Heath-caring product having protecting function for chemical liver injury - Google Patents
Heath-caring product having protecting function for chemical liver injury Download PDFInfo
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- CN1301070C CN1301070C CNB2005100333975A CN200510033397A CN1301070C CN 1301070 C CN1301070 C CN 1301070C CN B2005100333975 A CNB2005100333975 A CN B2005100333975A CN 200510033397 A CN200510033397 A CN 200510033397A CN 1301070 C CN1301070 C CN 1301070C
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Abstract
The present invention discloses a heath-care food with a protecting function for chemical liver injury, which is prepared from sodium alginate, pearl layer powder and taurine as raw materials, has the advantages of peculiar formula and specific efficiency, and is natural without toxic or side effect. The heath-care food has the functions of avoiding and preventing chemical liver injury, reducing GPT (glutamate-pyruvate transaminase) effectively, protecting and nourishing liver cells and resisting liver fibrosis.
Description
Technical field
The present invention relates to a kind ofly has the health food of protective effect to chemical damage, relate in particular to a kind of with the marine organism extract be feedstock production chemical damage is had the health food of protective effect.
Background technology
China is the district occurred frequently of hepatitis, with the hepatitis B is example, and China once was subjected to hepatitis b virus infected crowd up to more than 700,000,000, and wherein people more than 1.2 hundred million carries virus throughout one's life, wherein 3,000 ten thousand people will develop to cirrhosis, and the nearly 3%-5% of cirrhosis can develop into liver cancer.The chronic liver parenchyma inflammation, the necrosis that continue can cause the continual fibroplasia of liver and form liver fibrosis, and develop to cirrhosis.Because living standard improves, and dietary structure changes and the prevention and health care measure relatively lags behind, the pathogenesis of fatty liver rate is still rising, and the incidence of disease age is more and more littler in recent years.The variation of social environment on the other hand brings the new synthetic medicament and the increase of chemicals, even brings the pollution and the public hazards thereof of environment, and it is the same with alcoholism, is the straight reason that produces chemical damage.Hepatopathy has seriously reduced patient's quality of life, has shortened patient's life-span.
At present, most of hepatopaths mainly are by drug therapy.The treatment of hepatitis be one comprehensive, the process of nursing someone with the best care, in this process, the patient wants medication inevitably, take medicine, this is reduced to the limit to medicine to the side effect of human body with regard to requiring, preferably patient's liver is not produced any harm, because, in case the medicine toxic side effect, the liver that so this toxic and side effect can only rely on patient is removed, patient's the liver liver function that originally sustained damage is unsound, so since, vicious circle, the impariment of the liver again when controlling liver is controlled the liver medicine and has been become double-edged sword.The toxic and side effect of Western medicine is that treatment of diseases has been added new difficult factor, even makes on patient's disease and add disease.Though Chinese medicine has been compared advantageous advantage with Western medicine, because the modern industry development, environmental pollution is serious, and Chinese medicine is polluted in growth course inevitably, thereby has aggravated the Chinese medicine toxic and side effect.In therapeutic process, the patient takes medicine in a large number, and is but ineffective eventually, or liver function instead occurring descends the phenomenon that sb.'s illness took a turn for the worse.Therefore, in the process of treatment hepatopathy, avoid and prevent to have the liver cell of inflammation further to be subjected to chemical damage, build a good living environment to liver cell, the protection chemical damage has just become the effective way of supplemental treatment chronic hepatitis.
The objective of the invention is the marine organism extract scientific composition of utilizing physiologically active very strong, be refined in the chronic hepatitis treatment process and chemical damage had the natural marine health food that has no side effect of protective effect.
The present domestic health food that chemical damage is had protective effect; mainly be that to select the Chinese herbal medicine of medicine-food two-purpose for use with reference to the mechanism of treatment by Chinese herbs hepatopathy be that raw material prepares; the toxic and side effect that has similar Chinese medicine that effect is quite a lot of, toxic and side effect is the then DeGrain of some gently.
With the Chinese medicine be raw material chemical damage is had the health food of protective effect, its composition complexity, effective component is indeterminate, majority is that employing property belongs to cold Chinese medicine, reaches the hepatocellular purpose of protection by falling irascibility.
Adopt marine organisms be raw material have the health food of protective effect seldom to see to chemical damage; separation and Extraction goes out multiple marine bioactivity thing from marine organisms; to start the liver immune system; the prevention liver fibrosis, fall that poison detoxifcation alleviates burden of liver, irascibility falls in heat-clearing; be the good living environment of hepatocellular construction, chemical damage is had protective effect is that the pure natural oceanic health food of purpose is not seen as yet in the hope of reaching comprehensive high-efficiency.
Summary of the invention
The object of the present invention is to provide a kind of instant effect, the GPT (glutamic-pyruvic transaminase) due to chemical damage, fatty liver and other hepatocellular injuries is raise all comparatively significantly food therapy effect, and do not have a poisonous side effect of medicine chemical damage is had the health food of protective effect.
Solution of the present invention is based on understanding and the principle to chemical damage and prevention liver fibrosis, and to the understanding of marine bioactivity thing, with reference to modern Chinese and western medical science and pharmacological research achievement, from marine organism extract, filter out multiple marine bioactivity thing with very strong physiologically active, scientific composition, make it bring into play following effect: 1. start the immune system of liver self, impel the liver of damage to recover and hepatocellular regeneration; 2. irascibility fall in calming the liver, energy heat-clearing, and the prevention liver fibrosis is built good living environment to liver cell; 3. fall the poison detoxifcation, alleviate synthetic medicament and chemicals hepatocellular damage; 4. hinder the synthetic of fat and delay fatty absorption, prevent the generation of fatty liver, thereby alleviate burden of liver.
Health food of the present invention is made by the raw material of following weight percentage:
Sodium alginate 5～85%
Nacreous layer powder 5～85%
Taurine 10～90%.
The preferred weight proportioning for preparing health food of the present invention is:
Sodium alginate 15～65%
Nacreous layer powder 15～65%
Taurine 20～70%.
The above-mentioned health food that is used to protect chemical damage by common process, can be made said multiple formulation on the pharmacy, as capsule, tablet, powder, electuary, paste or granule.
An important feature of the present invention is that sodium alginate is regulated the immune mechanism of action of liver, the control of liver fibrosis is the various chronic liver diseases of treatment, the main aspect that the control cirrhosis forms, the main cause of chronic hepatitis B cellular damage is relevant with the caused immunologic derangement of hepatitis type B virus.Recent medical research finds that chronic persisting hepatitis and chronic active hepatitis (CAH) have the phenomenon of cellular immunity and humoral immunity underactivity.Sodium alginate has heat-clearing, soft heavily fortified point, dissipating bind, activates blood circulation and disperses blood clots, the function of improving microcirculation, regulating immunologic function and control liver fibrosis.It suppresses on the one hand indirectly, and GPT synthesizes (glutamic-pyruvic transaminase) in the liver cell, and by alleviating the pathologic process of hepatic injury, protection membrane structure and functional integrity reduce the release of GPT on the one hand.By swashing intravital T lymphocyte, start the immune system of liver self, impel the liver of damage to recover and hepatocellular regeneration, increase the synthetic of hepatic glycogen, improve body's immunity, thereby play the hepatocellular effect of protection.
Another important feature of the present invention is the function that irascibility falls in nacreous layer powder.The hepatopath, liver is showing tremendous enthusiasm arrogant, and mood and hot food all can increase the weight of hepatocellular damage.It is salty, cold that the nacre mealiness belongs to, and returns liver, the heart channel of Hang-Shaoyin.Through the nacreous layer powder of normal temperature, physical treatment, have effect calming the liver, that arresting convulsion makes eye bright, it is dizzy to be used to have a headache, irritated insomnia, the hot hot eyes of liver, the empty blurred vision of liver.Can heat-clearing fall irascibility, build good living environment to liver cell.
Another one important feature of the present invention is that the Taurine in this health food is a kind of sulfur-containing amino acid in people and the animal body, has important function to keeping the humans and animals normal physiological function.Alcohol, synthetic medicament and chemicals all can have disrupting biofilm 26S Proteasome Structure and Function in various degree, cause necrosis of liver cells, make the interior transaminase of cell be released into blood and cause the active rising of GPT.GPT is one of important indicator of reflection liver lysosome stability or degree of injury, CCl
4(carbon tetrachloride) is the hepatocellular chemical substance of damage, liver cell contact CCl
4The inner synthetic Taurine ability in back improves, and Taurine can reduce the release of GPT, thereby plays the hepatocellular effect of protection.Taurine has heat clearing and inflammation relieving, reduces the function of the toxicity of many medicines and other toxic materials, and the liver lysosome membrane is had stabilization.
In addition, sodium alginate is a high-purity edible fiber, forms the very high colloidal solution of viscosity after the suction swelling, and food paste rises because of viscosity after taking in sodium alginate, thereby the holdup time of food and extend paste in stomach, has delayed the process of digesting and assimilating of fats.Next is to have the activity that suppresses pancreatic lipase, stops fat to be broken down into aliphatic acid and β-monoglyceride and is absorbed, thereby reduce body to the synthetic of fat and delay the absorption of body to fat, prevents the generation of fatty liver, alleviates burden of liver.
In addition, health food effective component of the present invention is clear and definite, and steady quality is easy to control.
Health food of the present invention is by functional experiment, and the result shows to have following advantage:
1, to select marine organism extract for use be raw material in the present invention, and component is few, flat flavor, instant.Natural having no side effect meets state food health legislation regulation.
2, health food of the present invention raises to the GPT due to various chemical damages and other hepatocellular injuries all comparatively significantly effect, and does not have the toxic and side effect of medicine.
3, health food of the present invention can be taken under the situation of not drug withdrawal, also can take separately.
4, health food of the present invention has auxiliary preferably dietary function to the rehabilitation clients of hepatitis.
5, health food of the present invention has softening and resolving hard mass, hinders the effect that fat absorption prevents that fatty liver from generating.
The present invention is further illustrated below in conjunction with the specific embodiment and contractile studies.
The specific embodiment
Embodiment 1
Health food of the present invention is made by the raw material of following weight percentage:
Sodium alginate 10%
Nacreous layer powder 10%
Taurine 80%.
The production method of said components being made capsule is: (1) respectively with raw material drying, be crushed to the fineness more than 80 orders; (2) above-mentioned pulvis component in proportion after the mixed preparing, is used the auxilliary photograph of gamma rays, sterilize, sterilize, the actual absorption dosage of product is 5.0KGY, press filled capsules operation filled capsules, and bottling is packed.
Embodiment 2
Health food of the present invention is made by the raw material of following weight percentage:
Sodium alginate 20%
Nacreous layer powder 60%
Taurine 20%.
The production method of said components being made electuary is: (1) respectively with raw material drying, be crushed to the fineness more than 80 orders; (2) above-mentioned pulvis component in proportion after the mixed preparing, is used the auxilliary photograph of gamma rays, sterilize, sterilize, the actual absorption dosage of product is 5.0KGY, prepares electuary by the electuary operation, packing.
Embodiment 3
Health food of the present invention is made by the raw material of following weight percentage:
Sodium alginate 60%
Nacreous layer powder 20%
Taurine 20%.
The production method of said components being made tablet is: (1) respectively with raw material drying, be crushed to the fineness more than 80 orders; (2) above-mentioned pulvis component in proportion after the mixed preparing, is used the auxilliary photograph of gamma rays, sterilize, sterilize, the actual absorption dosage of product is 5.0KGY, prepares tablet by the film-making operation, packing.
Contractile studies
The present invention has the lipid peroxidation that suppresses impaired hepatic tissue to the carbon tetrachloride poisoning small white mouse, can obviously suppress because the rising of the caused serum glutamic pyruvic transminase vigor of carbon tetrachloride.Residual liver nuclear fission phase number showed increased under effect of the present invention, the regeneration degree is higher than control group, and illustrating has the promotion palingenesis to liver cell.The present invention can alleviate the pathology damage of toxicity small white mouse hepatic tissue in the experiment, impels the liver of damage to recover and hepatocellular regeneration, increases the synthetic of hepatic glycogen, and improves body's immunological function.
Claims (3)
1, a kind of have the health food of protective effect to chemical damage, it is characterized in that it is to be made by following raw materials in percentage by weight:
Sodium alginate 5～85%
Nacreous layer powder 5～85%
Taurine 10～90%.
2, according to claim 1 have the health food of protective effect to chemical damage, and wherein the weight percentage of each raw material is:
Sodium alginate 15～65%
Nacreous layer powder 15～65%
Taurine 20～70%.
3, according to claim 1 and 2 have the health food of protective effect to chemical damage, and the formulation that it is characterized in that health food is capsule, tablet, powder, electuary, paste or granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100333975A CN1301070C (en) | 2005-03-07 | 2005-03-07 | Heath-caring product having protecting function for chemical liver injury |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100333975A CN1301070C (en) | 2005-03-07 | 2005-03-07 | Heath-caring product having protecting function for chemical liver injury |
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| Publication Number | Publication Date |
|---|---|
| CN1663449A CN1663449A (en) | 2005-09-07 |
| CN1301070C true CN1301070C (en) | 2007-02-21 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005100333975A Active CN1301070C (en) | 2005-03-07 | 2005-03-07 | Heath-caring product having protecting function for chemical liver injury |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108617779B (en) * | 2018-03-29 | 2021-12-28 | 新疆旺源生物科技集团有限公司 | Camel milk composition with auxiliary protection effect on chemical liver injury |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1105244A (en) * | 1994-05-23 | 1995-07-19 | 中国科学院动物研究所 | Marine full-pearl shell powder and preparing process thereof |
| CN1280834A (en) * | 2000-06-20 | 2001-01-24 | 罗世江 | Water-soluble pearl component and its preparing process |
| CN1456097A (en) * | 2003-04-26 | 2003-11-19 | 李扬远 | Functional marine food and producing method thereof |
| CN1476782A (en) * | 2002-08-20 | 2004-02-25 | 北京京港耀新生物技术开发有限公司 | Preparation process of complete-component pearl product |
-
2005
- 2005-03-07 CN CNB2005100333975A patent/CN1301070C/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1105244A (en) * | 1994-05-23 | 1995-07-19 | 中国科学院动物研究所 | Marine full-pearl shell powder and preparing process thereof |
| CN1280834A (en) * | 2000-06-20 | 2001-01-24 | 罗世江 | Water-soluble pearl component and its preparing process |
| CN1476782A (en) * | 2002-08-20 | 2004-02-25 | 北京京港耀新生物技术开发有限公司 | Preparation process of complete-component pearl product |
| CN1456097A (en) * | 2003-04-26 | 2003-11-19 | 李扬远 | Functional marine food and producing method thereof |
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| Publication number | Publication date |
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| CN1663449A (en) | 2005-09-07 |
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