CN105361171B - One kind having composition for relieving physical fatigue - Google Patents
One kind having composition for relieving physical fatigue Download PDFInfo
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- CN105361171B CN105361171B CN201510897184.0A CN201510897184A CN105361171B CN 105361171 B CN105361171 B CN 105361171B CN 201510897184 A CN201510897184 A CN 201510897184A CN 105361171 B CN105361171 B CN 105361171B
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- parts
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- physical fatigue
- american ginseng
- relieving physical
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- 239000000203 mixture Substances 0.000 title claims abstract description 17
- 239000000843 powder Substances 0.000 claims abstract description 23
- 240000005373 Panax quinquefolius Species 0.000 claims abstract description 16
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 16
- 241000894006 Bacteria Species 0.000 claims abstract description 13
- 229940087603 grape seed extract Drugs 0.000 claims abstract description 13
- 235000002532 grape seed extract Nutrition 0.000 claims abstract description 13
- 239000001717 vitis vinifera seed extract Substances 0.000 claims abstract description 13
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 206010016256 fatigue Diseases 0.000 abstract description 20
- 230000036541 health Effects 0.000 abstract description 5
- 230000002195 synergetic effect Effects 0.000 abstract description 2
- 230000009182 swimming Effects 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 239000000284 extract Substances 0.000 description 4
- 238000001914 filtration Methods 0.000 description 4
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 4
- 238000010992 reflux Methods 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 235000019441 ethanol Nutrition 0.000 description 3
- 238000000605 extraction Methods 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 238000010171 animal model Methods 0.000 description 2
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 description 2
- 229960001948 caffeine Drugs 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 description 2
- 235000021552 granulated sugar Nutrition 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 235000019359 magnesium stearate Nutrition 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 2
- 206010008111 Cerebral haemorrhage Diseases 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 241000282376 Panthera tigris Species 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 235000010980 cellulose Nutrition 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000009979 protective mechanism Effects 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 238000012109 statistical procedure Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 229960003080 taurine Drugs 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000005550 wet granulation Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses one kind having composition for relieving physical fatigue, is made of following raw materials by quality：1,250 2250 parts of American Ginseng, 300 500 parts of peacilomyce hepiahi bacterium powder, 60 100 parts of grape seed extract.It is demonstrated experimentally that each component of composition of the present invention has synergistic effect to alleviating physical fatigue.Inferior health and chronic fatigue crowd can be alleviated.
Description
Technical field
The present invention relates to one kind having composition for relieving physical fatigue.
Background technology
Fatigue is body under the conditions of certain environment, due to crossing for a long time or excessively heavy, nervous physical or mental labor
A kind of apparent temporarily-depressed physiological phenomenon of operating efficiency caused by dynamic.It is a kind of protective mechanism for people, this
It is that body sends out the signal that rest to us.No matter if ignored it, body will be damaged, and finally be overworked for a very long period into
Disease.Today's society is a fast-developing epoch, and keen competition has aggravated the pressure and burden of people, and staying up late for work becomes
" homely food ", few time enough rest to regain one's strength.It is chronically at fatigue state, excessive oxygen is accumulated in body
Decreased attention, failure of memory etc. " early ageing " symptom will occur in free radical, so that body is in " inferior health " state, seriously
It is also possible to other diseases can be caused.It has often been said that " overworking death " to be exactly actually long-term excessive fatigue cannot alleviate,
It dies suddenly to cause human body heart failure, caused by the illnesss such as lung declines, renal failure, myocardial infarction, cerebral hemorrhage." overworking death " people in recent years
Scholar increases year by year, keeps everybody health care consciousness more and more stronger.Health products base with function of physical fatigue alleviation currently on the market
This is all functional drink, such as " red ox " " happy tiger ", wherein the ingredients such as caffeine, taurine may be added to, is not suitable for length
Phase drinks.Therefore there is composition for relieving physical fatigue without containing ingredients such as caffeine, taurines there is an urgent need for a kind of.
Invention content
It is a kind of with composition for relieving physical fatigue the purpose of the present invention is overcoming the deficiencies of the prior art and provide.
Technical scheme of the present invention is summarized as follows：
One kind having composition for relieving physical fatigue, is made of following raw materials by quality：1250-2250 parts of American Ginseng,
300-500 parts of peacilomyce hepiahi bacterium powder, 60-100 parts of grape seed extract
Preferably American Ginseng is 1730 parts, peacilomyce hepiahi bacterium powder is 400 parts, grape seed extract is 80 parts.
Advantages of the present invention：
It is demonstrated experimentally that each component of composition of the present invention has synergistic effect to alleviating physical fatigue.Asia can be alleviated
Health and chronic fatigue crowd.
Specific implementation mode
With reference to specific embodiment, the present invention is further illustrated.
Peacilomyce hepiahi bacterium powder is purchased from Zhejiang pharmaceutical Co. Ltd of Wan Feng enterprise groups, meets its company standard.
Grape seed extract is purchased from Jianfeng Natural Product R＆D Development Co., Ltd., Tianjin, meets its company standard.
Raw material sources of the present invention, without limiting, meet other enterprises sale of above-mentioned standard to the present invention
Raw material can be used for the present invention.
Embodiment 1
One kind having composition for relieving physical fatigue, is made of following raw materials by quality：
1730 parts of American Ginseng, 400 parts of peacilomyce hepiahi bacterium powder, 80 parts of grape seed extract.
Embodiment 2
One kind having composition for relieving physical fatigue, is made of following raw materials by quality：
1250 parts of American Ginseng, 500 parts of peacilomyce hepiahi bacterium powder, 60 parts of grape seed extract.
Embodiment 3
One kind having composition for relieving physical fatigue, is made of following raw materials by quality：
2250 parts of American Ginseng, 300 parts of peacilomyce hepiahi bacterium powder, 100 parts of grape seed extract.
Embodiment 4
A kind of preparation with composition for relieving physical fatigue：
American Ginseng is taken, the ethanol water heating and refluxing extraction 1 that the volumetric concentration with American Ginseng 6 mass times is 70% is small
When, filtering；Volumetric concentration by residue 6 mass times is 70% ethanol water refluxing extraction 1 hour again, filtering；Merge filter
Liquid, the thick paste that relative density is 1.25 when being concentrated under reduced pressure into 70 DEG C, takes thick paste to be dried in vacuo (70 ± 5 DEG C), by dried object
It is ground into American ginseng extract fine powder.
By peacilomyce hepiahi bacterium powder, grape seed extract powder, American ginseng extract fine powder mixing.
Embodiment 5
The present invention's has influence of the composition for relieving physical fatigue to Tolerance of Swimming.
Experiment is that 2 grades of experiments are dynamic using C57 mouse (being used for Loaned swimming test), male and female dual-purpose, 18~22g of weight
Object.It is purchased from Beijing Vital River Experimental Animals Technology Co., Ltd., animal credit number：SCXK (capital) 2012-0001 is qualified
Card number is respectively 11400700006726.Each embodiment group is to prepare as described in Example 4.
Experimental animal is randomly divided into 13 groups：
1. Normal group (distilled water 0.4ml/ is only)；
2. 1 low dose group of embodiment (87.5mg/kg)；
3. 1 middle dose group of embodiment (175mg/kg)；
4. 1 high dose group of embodiment (350mg/kg)；
5. 2 low dose group of embodiment (87.5mg/kg)；
6. 2 middle dose group of embodiment (175mg/kg)；
7. 2 high dose group of embodiment (350mg/kg)；
8. 3 low dose group of embodiment (87.5mg/kg)；
9. 3 middle dose group of embodiment (175mg/kg)；
10. 3 high dose group of embodiment (350mg/kg)；
Peacilomyce hepiahi bacterium powder group (350mg/kg)；
Grape seed extract group (350mg/kg)；
American ginseng extract fine powder group (350mg/kg).
Each equal gastric infusion of dosage group mouse (each group adds water to be made into suspension in addition to Normal group), once a day.
According to experiment process, it is primary to weigh within every 2 days the weight of animals, adjusts dosage.Successive administration 45d, 0.5h, weighs after the last administration
Weight carries out mouse room temperature swimming with a load attached to the body experiment.The sink that water temperature is 24 ± 1 DEG C will be put into after mouse heavy burden (for weight 5%)
Went swimming, record mouse is from water is entered to the time in the flue.
Table 1. has influence of the composition for relieving physical fatigue to Tolerance of Swimming
Statistical procedures t is examined, compared with Normal group.
Embodiment 6
【Prescription】It is American Ginseng 1730g, peacilomyce hepiahi bacterium powder 400g, grape seed extract 80g, appropriate white granulated sugar, micro-
Appropriate crystalline cellulose, Magnesium Stearate proper quantity.
【Preparation method】American Ginseng is taken to be extracted 1 hour with 6 times of 70% alcohol refluxs of amount, filtering；By 6 times of 70% ethyl alcohol of amount of residue
Refluxing extraction 1 hour again, filtering；Extracting solution is merged, it is the thick of 1.20-1.30 (70 ± 5 DEG C) to be concentrated under reduced pressure into relative density
Cream.It takes thick paste to be dried in vacuo (70 ± 5 DEG C), dried object is ground into fine powder.
By peacilomyce hepiahi bacterium powder (fine powder), grape seed extract (fine powder), appropriate white granulated sugar (fine powder) and appropriate micro-
Crystalline cellulose (fine powder) carries out wet granulation, (65 ± 5 DEG C) of drying adds with above-mentioned American ginseng extract fine powder mixing with alcohol
Enter appropriate magnesium stearate, mixing tabletting.Chip select, it is qualified to examine, and is coated with Opadry, filling.
Claims (2)
1. one kind having composition for relieving physical fatigue, it is characterized in that being made of following raw materials by quality：American Ginseng 1250-
2250 parts, 300-500 parts of peacilomyce hepiahi bacterium powder, 60-100 parts of grape seed extract.
2. it is according to claim 1 a kind of with composition for relieving physical fatigue, it is characterized in that the American Ginseng is
1730 parts, the peacilomyce hepiahi bacterium powder be 400 parts, grape seed extract is 80 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510897184.0A CN105361171B (en) | 2015-12-08 | 2015-12-08 | One kind having composition for relieving physical fatigue |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510897184.0A CN105361171B (en) | 2015-12-08 | 2015-12-08 | One kind having composition for relieving physical fatigue |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105361171A CN105361171A (en) | 2016-03-02 |
| CN105361171B true CN105361171B (en) | 2018-08-03 |
Family
ID=55364257
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510897184.0A Active CN105361171B (en) | 2015-12-08 | 2015-12-08 | One kind having composition for relieving physical fatigue |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105361171B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105327025A (en) * | 2015-12-08 | 2016-02-17 | 天津中新药业集团股份有限公司第六中药厂 | Preparation method of composition capable of relieving physical fatigue |
| CN106174563A (en) * | 2016-07-15 | 2016-12-07 | 张标 | A kind of health product improving immunity of organisms |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1640488A (en) * | 2004-01-09 | 2005-07-20 | 蒋朝宗 | Method for preparing supermicro powder preparation of cordyceps sinensis mycelium |
| CN101190029A (en) * | 2006-11-28 | 2008-06-04 | 杨荣庆 | Pushing capsule and preparation method thereof |
| KR20090014320A (en) * | 2007-08-05 | 2009-02-10 | 구성학 | Maximowiczia chinensis, lycium chinese, torilis japonica, rubus coreanus miquel, cuscuta japonica chois ingredient included preservation composite and process of manufacture |
| CN102018068A (en) * | 2009-09-16 | 2011-04-20 | 上海优博生物技术有限公司 | Anti-fatigue tea and preparation method thereof |
| CN102232548A (en) * | 2011-08-08 | 2011-11-09 | 浙江天使生物工程有限公司 | Cordyceps militaris-American ginseng capsule health-care product and preparation process thereof |
| CN103156895A (en) * | 2011-12-11 | 2013-06-19 | 西安泰科迈医药科技有限公司 | Anti-fatigue capsule and preparation method for same |
| CN103519176A (en) * | 2013-10-22 | 2014-01-22 | 易金阳 | Yang tonifying and life extension cordyceps sinensis composition with effects of resisting fatigue, enriching blood and qi and replenishing essence |
-
2015
- 2015-12-08 CN CN201510897184.0A patent/CN105361171B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1640488A (en) * | 2004-01-09 | 2005-07-20 | 蒋朝宗 | Method for preparing supermicro powder preparation of cordyceps sinensis mycelium |
| CN101190029A (en) * | 2006-11-28 | 2008-06-04 | 杨荣庆 | Pushing capsule and preparation method thereof |
| KR20090014320A (en) * | 2007-08-05 | 2009-02-10 | 구성학 | Maximowiczia chinensis, lycium chinese, torilis japonica, rubus coreanus miquel, cuscuta japonica chois ingredient included preservation composite and process of manufacture |
| CN102018068A (en) * | 2009-09-16 | 2011-04-20 | 上海优博生物技术有限公司 | Anti-fatigue tea and preparation method thereof |
| CN102232548A (en) * | 2011-08-08 | 2011-11-09 | 浙江天使生物工程有限公司 | Cordyceps militaris-American ginseng capsule health-care product and preparation process thereof |
| CN103156895A (en) * | 2011-12-11 | 2013-06-19 | 西安泰科迈医药科技有限公司 | Anti-fatigue capsule and preparation method for same |
| CN103519176A (en) * | 2013-10-22 | 2014-01-22 | 易金阳 | Yang tonifying and life extension cordyceps sinensis composition with effects of resisting fatigue, enriching blood and qi and replenishing essence |
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| CN105361171A (en) | 2016-03-02 |
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Address after: 300401 Tianjin city Beichen District North Light Patentee after: Jinyao Darentang Group Co.,Ltd. No 6 Chinese Medicine Factory Address before: 300401 Tianjin city Beichen District North Light Patentee before: No. 6 Traditional Chinese Medicine Factory of Tianjin Zhongxin Pharmaceutical Group Co.,Ltd. |
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