CN105361171A - Composition with physical fatigue-relieving effect - Google Patents
Composition with physical fatigue-relieving effect Download PDFInfo
- Publication number
- CN105361171A CN105361171A CN201510897184.0A CN201510897184A CN105361171A CN 105361171 A CN105361171 A CN 105361171A CN 201510897184 A CN201510897184 A CN 201510897184A CN 105361171 A CN105361171 A CN 105361171A
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- Prior art keywords
- composition
- parts
- physical fatigue
- powder
- grape seed
- Prior art date
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- Granted
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- 239000000203 mixture Substances 0.000 title claims abstract description 22
- 230000000694 effects Effects 0.000 title abstract 2
- 239000000843 powder Substances 0.000 claims abstract description 23
- 240000005373 Panax quinquefolius Species 0.000 claims abstract description 16
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 16
- 229940087603 grape seed extract Drugs 0.000 claims abstract description 13
- 235000002532 grape seed extract Nutrition 0.000 claims abstract description 13
- 239000001717 vitis vinifera seed extract Substances 0.000 claims abstract description 13
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 238000002474 experimental method Methods 0.000 abstract description 5
- 241001416980 Paecilomyces hepiali Species 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
- 206010016256 fatigue Diseases 0.000 description 17
- 230000036541 health Effects 0.000 description 8
- 239000000284 extract Substances 0.000 description 5
- 230000009182 swimming Effects 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 4
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 description 4
- 238000010992 reflux Methods 0.000 description 4
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 230000037396 body weight Effects 0.000 description 3
- 238000000605 extraction Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 description 2
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 2
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 description 2
- 229960001948 caffeine Drugs 0.000 description 2
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 description 2
- 235000021552 granulated sugar Nutrition 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 2
- 239000008108 microcrystalline cellulose Substances 0.000 description 2
- 229940016286 microcrystalline cellulose Drugs 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 229960003080 taurine Drugs 0.000 description 2
- 238000001291 vacuum drying Methods 0.000 description 2
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- 206010008111 Cerebral haemorrhage Diseases 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 206010061216 Infarction Diseases 0.000 description 1
- 241000282376 Panthera tigris Species 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 206010042434 Sudden death Diseases 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000007574 infarction Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000012109 statistical procedure Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000005550 wet granulation Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention discloses a composition with a physical fatigue-relieving effect. The composition is prepared from the following raw materials in parts by weight: 1250-2250 parts of American ginsengs, 300-500 parts of paecilomyces hepiali powder and 60-100 parts of grape seed extract. Experiment results show that each component of the composition has a synergistic effect in relieving physical fatigue. The composition can relieve sub-health and long-term fatigue for people.
Description
Technical field
The present invention relates to a kind of composition with alleviating physical fatigue.
Background technology
Fatigue be body under certain environment condition, the obvious temporarily-depressed a kind of physiological phenomenon of operating efficiency caused owing to crossing long-time or too heavy, nervous muscle power or mental labour.Concerning the mechanism people being a kind of protectiveness, this is that health sends the signal had a rest to us.If no matter ignored it, health will suffer damage, and finally falls sick from overwork.Society is fast-developing epoch, and keen competition has increased the weight of pressure and the burden of people, and overtime work of staying up late becomes " homely food ", seldom has time enough to have a rest and regains one's strength.Be in fatigue state for a long time, accumulate too much oxygen radical in health, just there will be decreased attention, failure of memory etc. " early ageing " symptom, make health be in " inferior health " state, serious may cause other diseases in addition." overworking death " that it has often been said is actual is exactly that fatigue excessive for a long time can not get alleviating, thus the sudden death that the illnesss such as initiation human body heart failure, lung decline, renal failure, miocardial infarction, cerebral hemorrhage cause." overworking death " personage increased year by year in the last few years, made everybody health care consciousness more and more stronger.The health products in the market with alleviating physical fatigue function are substantially all functional drinks, as " red ox " " happy tiger " etc., wherein may with the addition of the composition such as caffeine, taurine, be not suitable for drinking for a long time.Therefore a kind of composition with alleviating physical fatigue not containing the composition such as caffeine, taurine is needed badly.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, a kind of composition with alleviating physical fatigue is provided.
Technical scheme of the present invention is summarized as follows:
There is a composition for alleviating physical fatigue, be made up of following raw material by quality: American Ginseng 1250-2250 part, bat pretty young woman paecilomycerol powder 300-500 part, grape seed extract 60-100 part
Preferably American Ginseng is 1730 parts, bat pretty young woman paecilomycerol powder is 400 parts, grape seed extract is 80 parts.
Advantage of the present invention:
Experiment proves, each component of composition of the present invention has synergy to alleviating physical fatigue.Inferior health and chronic fatigue crowd can be alleviated.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further illustrated.
Bat pretty young woman paecilomycerol powder, purchased from Zhejiang pharmaceutical Co. Ltd of Wan Feng enterprise group, meets its company standard.
Grape seed extract, purchased from Jianfeng Natural Product R&D Development Co., Ltd., Tianjin, meets its company standard.
Raw material sources of the present invention do not limit the present invention, and the raw material that other enterprise meeting above-mentioned standard sells also may be used for the present invention.
Embodiment 1
There is a composition for alleviating physical fatigue, be made up of following raw material by quality:
American Ginseng 1730 parts, 400 parts, bat pretty young woman paecilomycerol powder, grape seed extract 80 parts.
Embodiment 2
There is a composition for alleviating physical fatigue, be made up of following raw material by quality:
American Ginseng 1250 parts, 500 parts, bat pretty young woman paecilomycerol powder, grape seed extract 60 parts.
Embodiment 3
There is a composition for alleviating physical fatigue, be made up of following raw material by quality:
American Ginseng 2250 parts, 300 parts, bat pretty young woman paecilomycerol powder, grape seed extract 100 parts.
Embodiment 4
A kind of preparation with the composition of alleviating physical fatigue:
Get American Ginseng, be the ethanol water heating and refluxing extraction 1 hour of 70% by American Ginseng 6 quality volumetric concentration doubly, filter; Be 70% ethanol water refluxing extraction 1 hour again by residue by 6 quality volumetric concentration doubly, filter; Merging filtrate, when being evaporated to 70 DEG C, relative density is the thick paste of 1.25, gets thick paste and carries out vacuum drying (70 ± 5 DEG C), dry thing is ground into American ginseng extract fine powder.
By bat pretty young woman paecilomycerol powder, grape seed extract powder, the mixing of American ginseng extract fine powder.
Embodiment 5
The impact of composition on Tolerance of Swimming with alleviating physical fatigue of the present invention.
Experiment adopts C57 mouse (for Loaned swimming test), and male and female dual-purpose, body weight 18 ~ 22g, is 2 grades of animals used as test.All purchased from Beijing Vital River Experimental Animals Technology Co., Ltd., animal credit number: SCXK (capital) 2012-0001, the quality certification number is respectively 11400700006726.Each embodiment group prepares by the method for embodiment 4.
Animal used as test is divided into 13 groups at random:
1. Normal group (distilled water 0.4ml/ only);
2. embodiment 1 low dose group (87.5mg/kg);
3. dosage group (175mg/kg) in embodiment 1;
4. embodiment 1 high dose group (350mg/kg);
5. embodiment 2 low dose group (87.5mg/kg);
6. dosage group (175mg/kg) in embodiment 2;
7. embodiment 2 high dose group (350mg/kg);
8. embodiment 3 low dose group (87.5mg/kg);
9. dosage group (175mg/kg) in embodiment 3;
10. embodiment 3 high dose group (350mg/kg);
bat pretty young woman paecilomycerol powder group (350mg/kg);
grape seed extract group (350mg/kg);
american ginseng extract fine powder group (350mg/kg).
The equal gastric infusion of each dosage group mouse (except Normal group each group all add water be made into suspension), once a day.According to experiment process, within every 2 days, take the weight of animals once, adjustment dosage.Successive administration 45d, 0.5h after last administration, takes body weight, carries out mouse normal temperature swimming with a load attached to the body experiment.Put into after mouse heavy burden (for body weight 5%) the tank went swimming that water temperature is 24 ± 1 DEG C, record mouse is from entering water to the time in the flue.
Table 1. has the impact of composition on Tolerance of Swimming of alleviating physical fatigue
Statistical procedures t checks, all compared with Normal group.
Embodiment 6
[prescription] American Ginseng 1730g, bat pretty young woman paecilomycerol powder 400g, grape seed extract 80g, white granulated sugar is appropriate, microcrystalline cellulose is appropriate, Magnesium Stearate proper quantity.
[method for making] is got American Ginseng 6 times amount 70% alcohol refluxs and is extracted 1 hour, filters; By residue 6 times amount 70% ethanol refluxing extraction 1 hour again, filter; Extract is merged, is evaporated to the thick paste that relative density is 1.20-1.30 (70 ± 5 DEG C).Get thick paste and carry out vacuum drying (70 ± 5 DEG C), dry thing is ground into fine powder.
By bat pretty young woman paecilomycerol powder (fine powder), grape seed extract (fine powder), appropriate white granulated sugar (fine powder) and appropriate microcrystalline cellulose (fine powder), mix with above-mentioned American ginseng extract fine powder, wet granulation is carried out with alcohol, dry (65 ± 5 DEG C) and add appropriate dolomol, mixing compressing tablet.Chip select, is up to the standards, and uses Opadry dressing, filling.
Claims (2)
1. there is a composition for alleviating physical fatigue, it is characterized in that being made up of following raw material by quality: American Ginseng 1250-2250 part, bat pretty young woman paecilomycerol powder 300-500 part, grape seed extract 60-100 part.
2. a kind of composition with alleviating physical fatigue according to claim 1, is characterized in that described American Ginseng is 1730 parts, described bat pretty young woman paecilomycerol powder is 400 parts, grape seed extract is 80 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510897184.0A CN105361171B (en) | 2015-12-08 | 2015-12-08 | One kind having composition for relieving physical fatigue |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510897184.0A CN105361171B (en) | 2015-12-08 | 2015-12-08 | One kind having composition for relieving physical fatigue |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105361171A true CN105361171A (en) | 2016-03-02 |
| CN105361171B CN105361171B (en) | 2018-08-03 |
Family
ID=55364257
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510897184.0A Active CN105361171B (en) | 2015-12-08 | 2015-12-08 | One kind having composition for relieving physical fatigue |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105361171B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105327025A (en) * | 2015-12-08 | 2016-02-17 | 天津中新药业集团股份有限公司第六中药厂 | Preparation method of composition capable of relieving physical fatigue |
| CN106174563A (en) * | 2016-07-15 | 2016-12-07 | 张标 | A kind of health product improving immunity of organisms |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1640488A (en) * | 2004-01-09 | 2005-07-20 | 蒋朝宗 | Method for preparing supermicro powder preparation of cordyceps sinensis mycelium |
| CN101190029A (en) * | 2006-11-28 | 2008-06-04 | 杨荣庆 | Pushing capsule and preparation method thereof |
| KR20090014320A (en) * | 2007-08-05 | 2009-02-10 | 구성학 | Maximowiczia chinensis, lycium chinese, torilis japonica, rubus coreanus miquel, cuscuta japonica chois ingredient included preservation composite and process of manufacture |
| CN102018068A (en) * | 2009-09-16 | 2011-04-20 | 上海优博生物技术有限公司 | Anti-fatigue tea and preparation method thereof |
| CN102232548A (en) * | 2011-08-08 | 2011-11-09 | 浙江天使生物工程有限公司 | Cordyceps militaris-American ginseng capsule health-care product and preparation process thereof |
| CN103156895A (en) * | 2011-12-11 | 2013-06-19 | 西安泰科迈医药科技有限公司 | Anti-fatigue capsule and preparation method for same |
| CN103519176A (en) * | 2013-10-22 | 2014-01-22 | 易金阳 | Yang tonifying and life extension cordyceps sinensis composition with effects of resisting fatigue, enriching blood and qi and replenishing essence |
-
2015
- 2015-12-08 CN CN201510897184.0A patent/CN105361171B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1640488A (en) * | 2004-01-09 | 2005-07-20 | 蒋朝宗 | Method for preparing supermicro powder preparation of cordyceps sinensis mycelium |
| CN101190029A (en) * | 2006-11-28 | 2008-06-04 | 杨荣庆 | Pushing capsule and preparation method thereof |
| KR20090014320A (en) * | 2007-08-05 | 2009-02-10 | 구성학 | Maximowiczia chinensis, lycium chinese, torilis japonica, rubus coreanus miquel, cuscuta japonica chois ingredient included preservation composite and process of manufacture |
| CN102018068A (en) * | 2009-09-16 | 2011-04-20 | 上海优博生物技术有限公司 | Anti-fatigue tea and preparation method thereof |
| CN102232548A (en) * | 2011-08-08 | 2011-11-09 | 浙江天使生物工程有限公司 | Cordyceps militaris-American ginseng capsule health-care product and preparation process thereof |
| CN103156895A (en) * | 2011-12-11 | 2013-06-19 | 西安泰科迈医药科技有限公司 | Anti-fatigue capsule and preparation method for same |
| CN103519176A (en) * | 2013-10-22 | 2014-01-22 | 易金阳 | Yang tonifying and life extension cordyceps sinensis composition with effects of resisting fatigue, enriching blood and qi and replenishing essence |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105327025A (en) * | 2015-12-08 | 2016-02-17 | 天津中新药业集团股份有限公司第六中药厂 | Preparation method of composition capable of relieving physical fatigue |
| CN106174563A (en) * | 2016-07-15 | 2016-12-07 | 张标 | A kind of health product improving immunity of organisms |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105361171B (en) | 2018-08-03 |
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Address after: 300401 Tianjin city Beichen District North Light Patentee after: Jinyao Darentang Group Co.,Ltd. No 6 Chinese Medicine Factory Address before: 300401 Tianjin city Beichen District North Light Patentee before: No. 6 Traditional Chinese Medicine Factory of Tianjin Zhongxin Pharmaceutical Group Co.,Ltd. |