CN101731624B - Compound male silkworm moth health-care food for resisting senility and regulating immunity and preparation method - Google Patents
Compound male silkworm moth health-care food for resisting senility and regulating immunity and preparation method Download PDFInfo
- Publication number
- CN101731624B CN101731624B CN2009102634015A CN200910263401A CN101731624B CN 101731624 B CN101731624 B CN 101731624B CN 2009102634015 A CN2009102634015 A CN 2009102634015A CN 200910263401 A CN200910263401 A CN 200910263401A CN 101731624 B CN101731624 B CN 101731624B
- Authority
- CN
- China
- Prior art keywords
- male silkworm
- silkworm moth
- compound
- group
- moth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a compound male silkworm moth health-care food for resisting senility and regulating immunity, which is prepared by the following steps: (1) after drying male silkworm moths, controlling the constant temperature at 45 DEG C by adopting a squeezing and pulverizing mode, squeezing and pulverizing by adopting a spiral oil press, squeeze out an extract by a sieve of 12 meshes and collecting the sieved fine powder; (2) matching two medicinal materials of Chinese wolfberry and desertliving cistanche according to the ratio of 1:1 and carrying out spray drying to form powder after water extracting to obtain an extracting solid of the Chinese wolfberry and the desertliving cistanche; and mixing evenly so as to obtain the compound male silkworm moth health-care food. The compound male silkworm moth patent medicine has the characteristics of good efficacy, simple and effective prescription, smooth production process and the like and is used for resisting the senility of people and enhancing the immunity of the people.
Description
Technical field
The present invention relates to a kind of health food, is a kind of health food with anti-ageing, immunoloregulation function and preparation method thereof specifically.
Background technology
Along with progress of science and technology and expanding economy, people's rhythm of life is accelerated day by day, grows with each passing day from the pressure of each side such as work, life and society, and it is old and feeble to cause majority to be prone to, immunologic hypofunction.Aging be body with increasing age lentamente, the function reduction of progressive degenerative, disorderly general performance; It is the inexorable law of life process; It relates to many organs, and the decline of multisystem function and form and internal and external environment adaptive capacity and metabolic function is the biological phenomena of a complicacy.At present; The drug effect of prevention commonly used clinically and treatment aging is too single mostly; Can not improve the old and feeble sign of body, Chinese medicine then can more and more receive people's favor from angle enhances human body function, the raising resistance against diseases of comprehensively regulating because of it comprehensively.
Male silkworm moth contains several amino acids, vitamin and trace element, and is especially abundant with calcium, zinc, iron, cadmium content.Bioactivators such as a large amount of male sex hormones, juvenile hormone, brain hormone and moulting hormone in its body particularly are the good merchantable brands that integrates " integration of drinking and medicinal herbs " of dietotherapy, health, health care, help.
Some are arranged in the market is the functional health-care food of primary raw material with male silkworm moth; Like health foods such as male silkworm moths spirit, male silk moth capsules; Have antifatigue, improve the effect of immunity, but the shortcoming that these product formulation technologies fall behind: at first be that common drying and crushing is adopted in male silkworm moth powder process; Because the moth body and the moth wing are by local detachment, its patent medicine is renderd a service and is weakened; Secondly, the ubiquity prescription is complicated, and price is higher, contains a large amount of nourishing Chinese medicines, should not take for a long time, carries shortcomings such as inconvenience.
Summary of the invention
Above shortcoming in view of prior art the purpose of this invention is to provide the preparation method that a kind of master contains the compound male silkworm moth health food of male silkworm moth, makes it to overcome the deficiency of prior art, through the processing procedure of innovation, gives full play to the overall drug effect of male silkworm moth; And have that prescription is simple, technology is controlled, be easy to the characteristics of production and processing.
The present invention also aims to the compound male silkworm moth health food that provides a kind of master to contain male silkworm moth, be convenient for people to strengthen anti-ageing and raising immunity down in effective compound compatibility synergy.The objective of the invention is to realize like this:
The preparation method of the anti-ageing immunological regulation health food of a kind of compound male silkworm moth; Comprise following patent medicine step: male silk moth powder is after 30-50 ℃-oven dry low temperature drying in 15-25 hour; Squeeze (machine temperature is controlled within 45 ℃) one time through small-sized oil press, cross 12 mesh sieves, collect the fine powder after sieving.Matrimony vine and saline cistanche are extracted solid content and adopt following method to make: matrimony vine; Saline cistanche two flavor medicinal materials were by weight 1: 1 ratio compatibility; Amount of water is pressed 10 extraordinarily entry extractions of medicinal material gross weight, and twice, merge filtrating twice; Add the dry edible dextrin (weight adds by 1/2 of matrimony vine and saline cistanche medicinal material weight) of crossing 80 mesh sieves when heating is concentrated into relative density for 1.06-1.08, go into spray dryer powder process at 30-50 ℃.Merge male silkworm moth fine powder of above gained and matrimony vine saline cistanche and extract the solid content xeraphium, mixing promptly gets.
The anti-ageing immunological regulation health food of the compound male silkworm moth that adopts above method to make; Active principle is to get by following substances in parts by weight is evenly mixed: male silk moth powder (adult of the male Sichuan of Bombycidae silkworm Bombyx mori Linaeus) 20-80 part (weight portion; Down with), matrimony vine saline cistanche extraction solid content 15-60 part that matrimony vine (dry mature fruit of plant of Solanaceae lycium barbarum Lycium barbarum L.) and saline cistanche (succulent stem of the dry zone scale leaf of Orobanchaceae plant Inner Mongol saline cistanche Cistanche deserticolaY.C.Ma.) adopt as above technology to make.
The anti-ageing immunological regulation health food of compound male silkworm moth provided by the invention; Because male silkworm moth is adopted the special processing mode of pulverizing of pressing of squeezing; Moth body of male silkworm moth and moth alar part are pressed by the height extrusion; Male silkworm moth main component protein and lipid form effective fusion, compare with the drying and crushing of routine, play the uniqueness of activation drug effect and concoct effect.In addition, such greasy after the male silkworm moth that obtains of squeezing is pulverized unlike medicinal pulverizer can solve the technological requirement of the fluency that sieves.Through good prescription compatibility, make the medicinal effects synergy of three kinds of components, prescription is simple effectively, be easy to production and processing.
The specific embodiment:
Small-sized squeezer (the sx01 type Henan echo machinery adapted power 15-18kw of the Co., Ltd) discontinuity that the male silkworm moth of low temperature drying (in 15-25 hour drying of 30-50 ℃-oven dry) is used with peasant household's hot pickled mustard tube seed squeezes; Machine temperature is controlled at (generally 40-45 ℃ of scope, surpass this temperature and then shut down heat radiation, compressible is 5 kilograms in half an hour) about 45 ℃; Cross 12 mesh sieves; Fine powder after collection is sieved, rough segmentation stay once more and squeeze with oil press, and fine powder is for use.
Matrimony vine, saline cistanche two flavor medicinal materials were in 1: 1 ratio compatibility, and water is extraordinarily gone into by 10 of medicinal material total amount, and water extracts twice; Merge twice filtrating and add dextrin, dextrin (drying is crossed 80 mesh sieves) adds (respectively add 100g like matrimony vine, saline cistanche, then dextrin adds 50g) by 1/2 of single dose; In the time of 40 ℃, add and use the mixer mixing, filter, place electric furnace; It is to add spray dryer between the 1.06-1.08 that heating is concentrated into proportion, beats powder, gets powder; Pack is kept dry, and it is subsequent use to obtain matrimony vine saline cistanche extraction solid content.
By male silk moth powder: the matrimony vine saline cistanche is extracted solid content=20-80: 15-60 (weight portion) and evenly blends A, B, and the product of three kinds of different proportionings of C (is that heavy dose is 80: 60; Middle dosage is 40: 30; Low dose is 20: 15), make drug effect with positive thing and use contrast; Good effect is all arranged, wherein 40: 30 the bests (seeing following experimental result).
Medicinal effects is observed
(1) the antidotal effect of compound male silkworm moth capsule is observed
1 experiment material
1.1 animal used as test
Select 60 of healthy adult cleaning level Kunming white mouses for use, male, body weight 25 ± 5g, available from HuaXi college of pharmacy, SiChuan University Animal Experimental Study center, the conventional raising.
1.2 experiment medicine
(1) positive drug: Ginseng decoction.Genseng (the dry root of Araliaceae genseng Panax ginsengC.A.Mey.) is bought the big pharmacy of health shellfish in Chengdu.Preparation: take by weighing the 4.4g genseng in the 500ml large beaker, add suitable quantity of water and soak about 30min, place to decoct about 45min on the electric furnace, evaporation and concentration is promptly processed the Ginseng decoction that concentration is 0.022g/ml to 200ml, after the cooling, preserves with 4 ℃ of refrigerators, and is subsequent use.
(2) experimental drug: make the compound male silkworm moth capsule by preceding method, specification: 0.5g/ grain.
2 experimental techniques
2.1 the foundation of mice group and model of yang asthenia and medication
(1) animal divides into groups: 72 of healthy mices; Male; Be divided into 6 groups at random: dose drug group, compound male silkworm moth capsule low-dose drugs group in normal control group, model control group, positive drug control group, compound male silkworm moth capsule in high dose drug group, the compound male silkworm moth capsule, 12 every group.
(2) the mouse model of yang asthenia is set up: except that normal control group injection equal-volume physiological saline, all the other respectively organize all every intramuscular injection hydrocortisone (2mg/10ml) 0.2ml/d of mouse, and 7d causes model of yang asthenia continuously.In modeling, every of normal control group and model control group mouse are irritated stomach with physiological saline 0.6ml/d; Every of positive drug group mouse is irritated stomach with Ginseng decoction (0.022g/ml) 0.6ml/d; The high, medium and low dose groups mouse of compound male silkworm moth pharmaceutical capsules is irritated stomach, continuous 7 days with high, medium and low dosage soup (1.5g, 0.75g, 0.375g capsule 's content/d, this dosage is converted by people and animal-use drug dosage) respectively.
2.2 experimental technique
(1) mouse autonomic activities number of times determination experiment mouse autonomic activities number of times in 10min behind last administration 30min.
(2) superoxide dismutase (Superoxide Dismutase, SOD) and MDA (Maleic Dialdehyde, detection MDA).
This experiment adopts xanthine oxidase to measure the vigor of brain tissue SOD, and sulfo-barbital method (TBA method) is measured the content of brain tissue MDA.
2.3 statistical method
The completely random design is adopted in experiment.(x ± s) expression, the significance,statistical of difference is judged in the t check to experimental result between the employing group with mean ± standard deviation.
3 experimental results
3.1 symptom and sign are observed
The sign situation of each treated animal reacts good before the modeling, hair smoothing, and diet is normal, Quick off the mark.The most mouse of intramuscular injection hydrocortisone modeling the 5th day beginning model of yang asthenia group become thin, lassitude, movablely reduce, slow in reacting, the withered thin tarnish of chaeta, hogback also occurs and alarm symptoms such as hair, loose stool.Medication therapy groups and positive group compare with model group action more flexibly, big slightly, the hair of dietary amount is than moist, unusual behavior all has alleviation in various degree.
But deficiency of yang symptom is alleviated and improved to presentation of results compound male silkworm moth pharmaceutical capsules treatment group and Ginseng decoction's positive drug group antagonism hydrocortisone induced mice.
3.2 each group is to the influence of mouse autonomic activities number of times
Each group of table 1 is to the influence of experiment mice autonomic activities number of times (x ± s)
Annotate: represent P＜0.05 with compared with normal: ☆, ☆ ☆ representes P＜0.01; Compare with model control group: * representes P＜0.05; Compare with the positive drug group: # representes P＜0.05.
As test shown in the result, model group is compared the difference (P＜0.01) that highly significant is arranged with the normal control group, model of yang asthenia modeling success is described.Compound male silkworm moth capsule in high dose, middle dosage treatment group and positive drug group have been compared with model group than significant difference (P＜0.05); Explain that the compound male silkworm moth capsule is One's spirits are drooping to deficiency of yang mouse due to the hydrocortisone; Activity symptom slowly improves significantly; Significantly improve deficiency of yang mouse autonomic activities number of times (in experimentation; 1 of the dead mouse of normal control group, the dose groups mouse is each dead 2 in model control group, positive controls, medicine high dose group, the medicine, 3 of medicine low dose group dead mouses).
3.3 each group is to the influence of mouse brain tissue SOD and MDA
(1) each group is to the influence of mouse brain tissue SOD vigor, and experimental result is as shown in table 2:
Each group of table 2 is to the influence of experiment mice SOD (x ± s)
Annotate: with compared with normal: ☆ P＜0.05; Compare with model control group: * P＜0.05.
As test shown in the result, model group is compared brain tissue SOD vigor and is obviously reduced with the normal control group, significant difference (P＜0.05) is arranged, and model of yang asthenia modeling success is described.The compound male silkworm moth capsule is high, middle dosage treatment group is compared brain tissue SOD vigor with the positive drug group and obviously raise with model group; Have than significant difference (P＜0.05); Explain that the compound male silkworm moth capsule has tangible humidification to the brain tissue SOD vigor of deficiency of yang mouse due to the hydrocortisone; Thereby improve the ability that mouse is removed oxygen radical, delay senility.
(2) each organizes the influence of mouse brain being organized the MDA vigor, and experimental result is as shown in table 3:
Each group of table 3 is to the influence of experiment mice MDA (x ± s)
Annotate: with compared with normal: ☆ P＜0.05; Compare with model control group: * P＜0.05; * P＜0.01.
As test shown in the result, model group is compared brain tissue MDA content and is obviously raise with the normal control group, significant difference (P＜0.05) is arranged, and model of yang asthenia modeling success is described.The compound male silkworm moth capsule is high, middle dosage treatment group is compared brain tissue MDA content with the positive drug group and obviously reduced with model group; Highly significant difference (P＜0.01) is arranged; Explain that the compound male silkworm moth capsule has tangible reduction effect to the brain tissue MDA content of deficiency of yang mouse due to the hydrocortisone; Alleviate body inner lipid peroxidating degree, alleviate the cellular damage degree, thereby delay the senescence process of body tissue.
SOD is one of antioxidase important in the body, and its vigor and content have reflected the ability of body removing free radical.Research shows that with the growth at age, the ability that SOD removes free radical reduces gradually, so the height of SOD level is to weigh one of old and feeble important indicator.
Body aging, the Radical Metabolism meeting disequilibrium in the in-vivo tissue cell, body descends to the defence capability of free radical.The deposition of lipofuscin in cell tissue is the key character of organism aging process.The intermediate product that MDA forms as lipofuscin, its content can reflect the production and the peroxidating degree of body tissue cell to lipid of free radical in the body indirectly, so can be MDA as one of index of estimating aging.
This experiment is through the S&S of observation experiment mouse, and mensuration mouse swimming with a load attached to the body time, autonomic activities number of times, brain tissue SOD vigor, brain tissue MDA content are observed the compound male silkworm moth capsule to the antidotal effect of mouse.
Experimental result shows that the compound male silkworm moth capsule is similar with the positive drug Ginseng decoction, can obviously improve mouse deficiency of yang symptom; Prolong the mouse swimming with a load attached to the body time; Increase the autonomic activities number of times, improve the vigor of mouse brain tissue SOD, reduce the content that mouse brain is organized MDA.Show the ability that strengthens mouse muscle power, antifatigue, enhancing endurance, the antagonism deficiency of yang, removes free radical and reduction level of lipid peroxidation; Each dose groups and model group are more variant, and relevant with dosage, with the increase of dosage; These abilities strengthen, thereby reach certain antidotal purpose.
(2) the compound male silkworm moth capsule improves the effect observation of immunologic function
1 experiment material
1.1 animal used as test
Select 60 of healthy adult cleaning level Kunming white mouses for use, male, body weight 25 ± 5g, available from HuaXi college of pharmacy, SiChuan University Animal Experimental Study center, the conventional raising.
1.2 experiment medicine
(1) positive drug: Ginseng decoction.Genseng is bought the big pharmacy of health shellfish in Chengdu.
Ginseng decoction's preparation: take by weighing the 4.4g genseng in the 500ml large beaker, add suitable quantity of water and soak about 30min, place and decoct about 45min on the electric furnace; Evaporation and concentration is promptly processed the Ginseng decoction that concentration is 0.022g/ml, after the cooling to 200ml; Preserve with 4 ℃ of refrigerators, subsequent use.
(2) experimental drug: compound male silkworm moth capsule.The compound male silkworm moth capsule be the early stage preparation research during, the capsule medicine of processing.Specification: 0.5g/ grain.
The preparation of compound male silkworm moth capsule 's content soup: get 1.5g compound male silkworm moth capsule 's content porphyrize in mortar, add get behind an amount of distilled water appropriate amount of starch in mortar with capsule 's content porphyrize, mixing.Mixing liquid is gone in the small beaker, and adding distil water is heated to starch and becomes pasty state to 20ml on electric furnace, processes high dose and (contains the soup of 1.5g capsule 's content/20ml), cool off subsequent use.In dosage (contain 0.75g capsule 's content/20ml) and low dosage and (contain that the 0.375g capsule 's content/20ml) filling gastric juice is got final product by the high dose liquid diluting in use.
1.3 main agents
Phytohemagglutin phytolectin (phytohaemagglutinin, PHA): purchase Rui Sheng Science and Technology Ltd., specification 5mg/ bottle in Sichuan.
1.4 key instrument
Biomicroscope (BH one 2 types, OLYMPUSCo, LTO product)
Electro-heating standing-temperature cultivator (HHBll420 one S one 11 types, Shanghai make a leapleap forward medical apparatus and instruments factory's product)
Light microscope (XSP one 16A type, optical instrument factory, south of the River product)
Electronic balance (1004 types, Shanghai Precision Scientific Apparatus Co., Ltd's product)
2 experimental techniques
2.1 animal divides into groups
72 of healthy mices; Male; Be divided into 6 groups at random: dose drug group, compound male silkworm moth capsule low-dose drugs group in normal control group, model control group, positive drug control group, compound male silkworm moth capsule in high dose drug group, the compound male silkworm moth capsule, 12 every group.
2.2 experimental technique
(1) phytohemagglutin phytolectin (PHA) the lymphocyte transformation experiment of inducing
Experimental technique: mice group, modeling, administration add intramuscular injection 10mg/kg phytohemagglutin phytolectin in the 1st, 2,3 days every mouse of administration as stated.Administration every day 1 time, successive administration 7d.The 8th day docking blood sampling smear, Wright's staining, get under the oily mirror slide head, in, trail a machine counting lymphocyte, calculate conversion ratio.
200 of lymphocyte transformation rate %=(lymphocyte number of conversion * 100%)/TLC
2.3 statistical method
The completely random design is adopted in experiment.(x ± s) expression, the significance,statistical of difference is judged in the t check to experimental result between the employing group with mean ± standard deviation.
3 results
Experimental result is as shown in table 4:
Each group of table 4 is to the influence of experiment mice lymphocyte transformation rate (x ± s)
Annotate: with compared with normal: ☆ P＜0.001; Compare with model group: * * P＜0.001.
Experimental result shows, compares with the normal control group, and model group PBLC conversion ratio significantly reduces (P＜0.001), explains that the immunocompromised model prepares successfully.With the model group ratio, high, middle dosage compound male silkworm moth pharmaceutical capsules treatment group and Ginseng decoction's positive drug group all can make the PBLC conversion ratio raise, and there were significant differences (P＜0.001) for dose groups and positive drug group and model group in its Chinese traditional medicine.
The auxiliary process experiment shows saline cistanche two flavor medicinal materials by 1: 1 compatibility, and water extracts twice, and water inventory is extraordinarily gone into by 10 of medicinal material total amount, merges filtrating twice; Be controlled at 40 ℃ and added the dry dextrin stirring and evenly mixing of 80 mesh sieves by 1/2 of simple weight; It is that to carry out spraying drying powder-forming between the 1.06-1.08 be to have the working condition of technology fluency and cost control preferably that heat is concentrated into proportion.
Basic scheme based on the present invention proposes can have multiple variation when actual production is made, such as, edible dextrin can use other edible adjuvants of this ratio value (being the relative weight ratio of active material) to add that the solid shape of health care replaces.Health food can be processed pill, tablet, soft capsule, hard shell capsules, granule, oral liquid etc. according to actual needs.
The processing processing procedure fluency of male silkworm moth: see from the angle of technology,, be unfavorable for and other medicinal material batchings and filling capsule because male silkworm moth main component is protein and lipid; Or utilize the grease absorption of the male silkworm moth after oil-Absorbing Sheets will be pulverized clean, though can obtain being beneficial to particle very time-consuming and the oil-Absorbing Sheets of loading capsule at last, render a service and improve processing cost but can influence patent medicine.Such greasy after the male silkworm moth that the present invention squeezing obtains is pulverized unlike medicinal pulverizer; Can satisfy the demand that smoothness is sieved; Particle after sieving can with other batch mixes evenly and satisfy the condition of loading capsule, and the meal after sieving can carry out twice pressing.
Claims (2)
1. the preparation method of the anti-ageing immunological regulation health food of compound male silkworm moth comprises following patent medicine step:
(1) male silkworm moth is after 15-25 hour drying of 30-50 ℃ of oven dry, and through adopting the mode of pulverizing of pressing of squeezing, thermostatic control is at 45 ℃, adopts screw oil expeller to squeeze to press to pulverize, and extract is crossed 12 mesh sieves, collects the fine powder after sieving;
(2 matrimony vines, saline cistanche two flavor medicinal materials were by 1: 1 compatibility, and water extracts twice, and water inventory is extraordinarily gone into by 10 of medicinal material total amount, merges filtrating twice; Be controlled at 40 ℃ and added the dry dextrin stirring and evenly mixing of 80 mesh sieves by 1/2 of simple weight; It is to carry out spraying drying powder-forming between the 1.06-1.08 that heat is concentrated into proportion; Obtain the matrimony vine saline cistanche and extract solid content;
(3) above two step gains evenly mix in proportion, and weight ratio is: male silk moth powder 40 weight portions, the matrimony vine saline cistanche is extracted solid content 30 weight portions, obtains product.
2. according to the anti-ageing immunological regulation health food of the said compound male silkworm moth of claim 1, it is characterized in that: said health food can be made into pill, tablet, soft capsule, hard shell capsules, granule, oral liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102634015A CN101731624B (en) | 2009-12-15 | 2009-12-15 | Compound male silkworm moth health-care food for resisting senility and regulating immunity and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102634015A CN101731624B (en) | 2009-12-15 | 2009-12-15 | Compound male silkworm moth health-care food for resisting senility and regulating immunity and preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101731624A CN101731624A (en) | 2010-06-16 |
| CN101731624B true CN101731624B (en) | 2012-05-09 |
Family
ID=42456037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009102634015A Expired - Fee Related CN101731624B (en) | 2009-12-15 | 2009-12-15 | Compound male silkworm moth health-care food for resisting senility and regulating immunity and preparation method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101731624B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104126775A (en) * | 2014-06-23 | 2014-11-05 | 王奎 | Duck meat nourishing glutinous fragrant rice and preparation method thereof |
| CN108124964A (en) * | 2017-12-11 | 2018-06-08 | 长春三真实业有限公司 | A kind of establishing-Yang male silk moth milk tablet |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1403564A (en) * | 2002-07-27 | 2003-03-19 | 战青芳 | Nourishing male silk moth wine and its making process |
-
2009
- 2009-12-15 CN CN2009102634015A patent/CN101731624B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1403564A (en) * | 2002-07-27 | 2003-03-19 | 战青芳 | Nourishing male silk moth wine and its making process |
Non-Patent Citations (2)
| Title |
|---|
| 刘绍等.食品免疫与免疫食品新进展.《实用预防医学》.2004,第11卷(第3期),第635－636页. * |
| 周宝宽.抗疲劳防治亚健康中药整理与研究.《中华中医药学刊》.2008,第26卷(第1期),第193-195页. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101731624A (en) | 2010-06-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103099089B (en) | Health-care product for reducing blood sugar and blood pressure, relaxing bowels, losing weight, resisting fatigue and improving sexual function and production technology thereof | |
| CN102907604B (en) | Health-care product having effects of reducing blood sugar and pressure, losing weight, relaxing bowels, maintaining beauty and resisting fatigue and production process thereof | |
| CN102919836B (en) | Health-care product capable of reducing blood glucose, releasing pressure, reducing lipid, relaxing bowel, beautifying, losing weight and resisting fatigue and production process thereof | |
| US20190328817A1 (en) | Traditional chinese medicine healthcare preparation for fat elimination and weight reduction | |
| CN102406860A (en) | Composition for preventing and treating diabetes, and preparation method and use thereof | |
| CN103417837B (en) | Medlar health preserving cream of a kind of medicine-food two-purpose and preparation method thereof | |
| CN104095231B (en) | A kind of health products containing agate coffee, the stem of noble dendrobium, American Ginseng and preparation method thereof | |
| CN102652801A (en) | Chinese herbal medicine tea bag for lowering blood sugar and preventing diabetes mellitus complications | |
| CN105532998A (en) | Health-care tea containing cordyceps militaris and preparation method thereof | |
| CN103734421A (en) | Liver-benefiting kidney-tonifying stomach-invigorating tea and preparation method thereof | |
| CN102178217B (en) | Konjac-flour-containing mixture and preparation method thereof | |
| CN104432063B (en) | Composition for alleviating athletic fatigue and preparation method thereof | |
| CN104187681B (en) | A kind of reducing blood sugar and blood fat health food and preparation method thereof | |
| CN102579836A (en) | Traditional Chinese medical dendrobium huoshanense composition and preparation method thereof | |
| CN107156416A (en) | A kind of skin-protecting face nursing lycium ruthenicum candy and preparation method thereof | |
| CN101731624B (en) | Compound male silkworm moth health-care food for resisting senility and regulating immunity and preparation method | |
| KR20160141027A (en) | Phamaceutical composition or healthy food comprising water extracts from Pleurotus eryngii var. ferulea (Pf.). for treating or preventing metabolic disorder | |
| CN102389114B (en) | Health food with the function of physical fatigue alleviation and preparation method thereof | |
| CN108066384A (en) | A kind of Chinese medicine preparation with strengthen immunity and preparation method thereof | |
| CN105495603A (en) | Preparation method for radix ginseng rubra-fructus crataegi cell-wall breaking superfine powder | |
| CN101120750A (en) | Method for preparing ginkgo bee product | |
| CN105101817A (en) | Edible composition, preparation method therefor, and food product comprising the composition | |
| CN105832877A (en) | Health-care product with liver-protecting effect and preparation method and application thereof | |
| JP2019034902A (en) | Composition | |
| CN102599312A (en) | Oligosaccharide Panax notoginseng sweet tea and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120509 Termination date: 20141215 |
|
| EXPY | Termination of patent right or utility model |