CN102599312A - Oligosaccharide Panax notoginseng sweet tea and preparation method thereof - Google Patents
Oligosaccharide Panax notoginseng sweet tea and preparation method thereof Download PDFInfo
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Abstract
The invention relates to an oligosaccharide Panax notoginseng sweet tea as a functional concentrated tea product and a preparation method of the oligosaccharide Panax notoginseng sweet tea. The oligosaccharide Panax notoginseng sweet tea consists of the following materials by weight: 10-35% of Panax notoginseng leaf/flower extract containing total notoginsenosides, 5-30% of Lithocarpus polystachyus sweet tea extract containing sweetener and sweet tea flavone, 10-30% of Eucommia ulmoides leaf extract and 10-45% of cottonseed oligosaccharide. The preparation method comprises the following steps of combining the active ingredients of the Panax notoginseng leaf/flower extract, the Lithocarpus polystachyus sweet tea extract, and Eucommia ulmoides leaf extract including the total notoginsenosides, the sweet tea flavone and chlorogenic acid to form molecular groups, mixing the obtained mixture and the cottonseed oligosaccharide fully and uniformly, and granulating, so as to obtain raw material of the oligosaccharide Panax notoginseng sweet tea. The Panax notoginseng sweet tea can effectively regulate the endocrine disturbance of human, regulate the alimentation of the gastrointestinal tract and enhance the immunity function, and has dietary therapeutic values in the aspects of prevention and adjuvant therapy for special groups with endocrine disturbance, diabetes, hypertension, hyperlipidemia, gastrointestinal tract inflammation, tumor diseases and the like.
Description
Technical field
According to modern life science and nutrition correlation theory, the present invention is a kind of practical instant tea-sweet tea of compound sugar pseudo-ginseng of special populations such as endocrine Nutrition and Metabolism functional disturbance (diabetes), high fat of blood, hypertension, intestines and stomach inflammation, atherosclerotic, tumor disease and preparation method thereof that is suitable for.
Background technology
The research of the sweet tea of compound sugar pseudo-ginseng is under the situation that present endocrine Nutrition and Metabolism functional disturbance (diabetes), high fat of blood, hypertension, gastroenteritis, atherosclerotic, tumor disease crowd not only increase and the application product research that launches.Research and development sweet tea raw material of compound sugar pseudo-ginseng and related preparations product are intended to satisfy above-mentioned disease patient crowd's living needs for above-mentioned disease patient provides a kind of practicality, the economic sweet taste tea new product of convenience.
The investigative technique background of the sweet tea of compound sugar pseudo-ginseng is on feasibility study relevant components material and the basis that becomes to be grouped into mechanism; Through the new formula combination raw material and the related preparations product of experimental study design, its raw material is made up of sanchi leaf/flower extract, multiple-ear rock Ke sweet tea extract, folium cortex eucommiae concentrated extract, cottonseed compound sugar.
1, sanchi leaf/flower extract
Pseudo-ginseng has another name called pseudo-ginseng, belongs to the Araliaceae herbaceos perennial, adopts and long three petioles of every strain because of digging in its after planting three to seven years, and each petiole is given birth to seven blades, so the name pseudo-ginseng.Its stem, leaf, Hua Junke are used as medicine.Sanchi leaf/flower extract is with sanchi leaf, spends the extract through concentrate drying.Modern pharmacology research shows that the main active ingredient of sanchi leaf/flower extract is arasaponin.(total saponins of Panax notognseng is the main effectively active component of araliaceae ginseng plant pseudo-ginseng PNS) to arasaponin, contains multiple monomer saponin.
(1) function of arasaponin: nearly 3 years " Advance on Pharmacological Activities of arasaponin " research is shown that arasaponin has extensive physiologically active at aspects such as cardio-cerebrovascular, hematological system, immune system, anti-inflammatories through researchers such as Changchun University of Traditional Chinese Medicine's good rain after a long drought, Xu Huibo; The function that confirmation has: (a) improve brain blood circulation: PNS ability expansion of cerebral vascular; Reduce cerebral vascular resistance, increase cerebral blood flow (CBF).PNS descends anesthesia rabbit femoral artery mean blood pressure (BMP) and cerebral vascular resistance (CVR), the BMP of anesthetized rat and CVR is descended, and be dose dependent, but not increase cerebral blood flow (CBF), and internal carotid is also had dilating effect.(b) promote the hematopoietic cell growth: PNS has proliferation function to hematopoietic cell; Can induce the synthetic increase of hematopoietic cell GATA 1 and GATA 2 transcriptional regulation proteins; And increase the activity that it combines with the promoter and the enhancer of upstream regulatory region, thereby the expression of regulation and control hematopoietic cell proliferation, differentiation associated gene.(c) antiinflammatory action: PNS has good anti-inflammatory activity to kinds of experiments property inflammatory model.It can suppress to scald the generation of back macrophage TNF α, and it is active to suppress NF KB. and intervene NF KB path, thereby reduced the expression of TNF α mRNA; Also can suppress leucocyte that carrageenan induces and swim out of with albumen and ooze out, reduce leukocyte count in the irrigating solution, stop MDA content to raise, suppress neutrophil leucocyte and discharge O
2-, increase cAMP content in the Neu, thereby reduce O
2Deng the lipid peroxidation injury that free radical brought out.(d) to Immune Effects: PNS has the effect of enhance immunity power; SPL increment, the conversion of ability obvious stimulation mouse promote mouse delayed allergy effect, improve mouse antibodies cellulation number; Improve the serum hemolysin level of mouse; Promote mouse monokaryon-macrophage carbon to clean up effect, strengthen monokaryon-peritoneal macrophage phagocytic activity of mouse, it is active to improve NK cells in mice.
(2) notoginsenoside antitumor action: researchers such as the yellow clear pine of basis institute of Guangdong Pharmaceutical University, Li Hongzhi, Zhang Yongli study anti-sudden change and the antitumor action of Panax Notoginseng saponin R g1 " anti-sudden change of Panax Notoginseng saponin R g1 and antitumor research " purpose, inquire into the drug effect of Panax Notoginseng saponin R g1 monomer.Method is observed the antitumous effect of Panax Notoginseng saponin R g1 with the antimutagenic effect of mouse Bone marrow cells micronucleus experiment and testicular chromosome distortion experiment observation Panax Notoginseng saponin R g1 with S-180 and H-22 transplanted tumor.Panax Notoginseng saponin R g1 all has the obvious suppression effect to the mouse testis cell chromosome that mouse Bone marrow cells micronucleus takes place and mitomycin the brings out distortion that endoxan brings out as a result; S-180 and the growth of H-22 mice transplanted tumor also there is the obvious suppression effect.Conclusion Panax Notoginseng saponin R g1 all has protective effect to the dna damage of body cell and reproduction cell, and mice transplanted tumor is also had certain tumor-inhibiting action.
2, Pasania cuspidata sweet tea extract
Pasania cuspidata (lithocarpus polystachyus Rehd) is called sweet tea, is the Fagaceae oak plant.Many scientists include sweet ingredient to the Pasania cuspidata Wild sweet tea and study; Chinese Academy of Sciences south China plant research institute in 1992 and Japan is all to be apt to change into Co., Ltd. and to cooperate; Identify carrying out molecular structure through 2 kinds of natural glucin crystallizations of repeatedly chemical purification acquisition; The result is that two kinds of crystallizations all contain first phloretin---the dihydrochalcone of same glucoside, claims the dihydrochalcone glycoside again, belongs to Flavonoid substances.Agricultural University Of Southwest in 1999 carries out nuclear magnetic resonance spectrometry to isolated sweet taste crystallization in the experiment and has confirmed that further this strong sweet taste thing is a dihydrochalcone.The sugariness of dihydrochalcone is 150 times of sucrose, and heat is merely one of three percentages of sucrose, and does not have bitter taste, avirulence.
(1) sweet tea extract has hypoglycemic, effect for reducing fat: through South China Science & Engineering University's light industry and Foodstuffs Academy Dong Hua Qiang, Ning Zhengxiang etc. its tender leaf of the sweet tea of " Pasania cuspidata flavones phloridzin is to the hypoglycemic blood fat effect of diabetic mice " research Pasania cuspidata is contained abundant flavones phloridzin.This research is with the Pasania cuspidata phloridzin (STPh) of separation and purification; Irritate the diabetic mice 18d that hello alloxan is induced with 4 dosage; Feeding together with non-model and model mice jar, amount distilled water compares; Irritate and feed the positive contrast of diabetes pill, detect its blood sugar (BG), serum triglyceride (TG), T-CHOL (TC), MDA (MDA) level and superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) activity then.The result shows, STPh handles BG, TG, TC and the MDA level that has reduced diabetic mice effectively, to increase SOD in serum, the GSH-Px activity also has obvious facilitation, wherein is optimal dose with 70mg/kgbwd.This shows that STPh has tangible positive role to diabetes control.
(2) sweet tea extract has hypoglycemic and non-toxic reaction: autonomous region's traditional Chinese medicine research institute Ceng Xianbiao, Wei Baowei etc. are to " research of Pasania cuspidata extract long term toxicity " through Guangxi, and the research purpose is observed the Pasania cuspidata extract and repeated to irritate the toxic reaction that stomach produces rat.Method high dose group (2g extract kg-1d-1), middle dose groups (1g extract kg-1d-1), low dose group (0.5g extract kg-1d-1) and blank group; Each 50 of rats; Irritate clothes Pasania cuspidata extract, continuous 25 weeks, 2 weeks during respectively at administration mid-term, drug withdrawal and after the drug withdrawal; Get the part rat and carry out 16 hematological indices, the inspection of 15 serum biochemistries indexs, microexamination 29 places' histopathologies change.Each administration group blood one sugar during administration is starkly lower than control group (P0.05) as a result, and liver function index is significantly higher than control group (P0.05) during the high dose group drug withdrawal, and degeneration of liver cells, and all the other each group inspections are not seen obviously unusual.Conclusion Pasania cuspidata extract oral administration has the effect of the rat blood sugar of reduction, outside the visible invertibity hepatotoxicity of long-term heavy dose of administration changes, does not see significantly other toxic reactions.
The sweet tea property of Pasania cuspidata is flat, flavor is sweet, clearing heat and promoting diuresis, tool food, medicine compatibility.Practice among the people confirms, sweet tea relieves heat and thirst, moistening lung, kidney tonifying, function such as hypotensive and hypoglycemic, and particularly diabetic's long-term drinking is received good blood sugar decreasing effect.It has natural pure, be of high nutritive value, health care is strong, unique flavor four big advantages, is a kind of wild rare resources that is of great rarity that western developed country is being sought.Wild area reaches more than 80,000 mu (5333 hectares) to multiple-ear rock Ke Wild sweet tea in the snowy peak mountain area, produces fresh and tender leaf per year and reaches more than 1600 ton, accounts for 1/5th of national total output.
3, folium cortex eucommiae concentrated extract
The bark of eucommia (Eucommiaulmoides) is an Eucommiaceae bark of eucommia platymiscium, is the endemic tree of the residual extinct plants and animal of China's third generation.The bark of eucommia is a traditional Chinese medical science traditional Chinese medicine material, and Ancient Chinese famous medical scholar's Compendium of Material Medica that Li Shizhen (1518-1593 A.D.) is shown of generation is carried " bark of eucommia can be gone into the liver kidney tonifying, bowl spares benefit vital essence, hard muscles and bones, strong will is controlled lumbago due to the kidney deficiency, obeys for a long time, and it is anti-old to make light of one's life by commiting suicide." bark of eucommia is classified top grade existing more than the 2000 year history of Chinese medicine as.The Li Shizhen (1518-1593 A.D.) day bark of eucommia " for a long time clothes make light of one's life by commiting suicide anti-old " is explained that the bark of eucommia is ill to cure the disease the effect of anosis health care.
Folium cortex eucommiae is the dried leaves of Eucommiaceae plant bark of eucommia Eucommia ulmoides Oliv..
(1) eucommia leaf extract composition and function: rely researchers such as beautiful China, Xu Liying, Rao Hua that " folium cortex eucommiae chemical composition and pharmacological research overview " research is being confirmed through the Jiangxi Prov. Medicine Inst: eucommia leaf extract contains chlorogenic acid, Geniposidic acid, Aucubin, flavonoids isoreactivity composition; Folium cortex eucommiae has immune-enhancing activity, regulates blood pressure, reduces blood sugar, regulates blood fat, antibiotic, antiviral, anti-ly stress, suppress pharmacological action such as growth of tumour cell; The chemical composition basically identical of folium cortex eucommiae and skin, folium cortex eucommiae and leatherware have equal effect aspect pharmacological effect.
(2) eucommia leaf extract is to the useful effect of treatment vascular hypertension: through researchers such as the Tang Zhi of medical college of University Of Nanhua break Peng Juan Jiang Jinlan at animal experiment study to " eucommia leaf extract is to the influence of clear-headed rat blood pressure ", purpose: observe eucommia leaf extract acute and chronic hypotensive effect.Method: measure clear-headed rat arteria caudalis blood pressure: (a) measure the blood pressure that spontaneous hypertensive rat (SHR) is repeatedly irritated the stomach eucommia leaf extract, observe its chronic hypotensive effect with indirect manometric method.(b) measure renal hypertensive rat and irritate behind the stomach eucommia ulmoides extracts 1,2,4,6 for 1 time, the blood pressure of 8h is to observe the acute hypotensive effect of extract.The result: (1) continuous 18d irritates stomach eucommia leaf extract 4.2g.kg-1 or 6.3g.kg-1 all obviously reduces the SHR blood pressure.(2) disposable filling eucommia leaf extract 4.2g.kg-1 or 6.3g.kg-1 all obviously reduce the renal hypertensive rat blood pressure.Conclusion: eucommia leaf extract has tangible reduction acute and chronic blood pressure.
4. cottonseed compound sugar
The main component of cottonseed compound sugar be raffinose, stachyose, disaccharides, polysaccharide wherein content maximum for raffinose, raffinose is claimed melitriose again, by the oligomeric trisaccharide that galactolipin, glucose and fructose are formed, molecular formula: C
18H
32O
16, molecular weight: 504, sugariness is about 23% of a sucrose.
Set forth through " cottonseed compound sugar one raffinose research overview "; The cottonseed compound sugar in a large number can not be for digesting zymolytic chemical bond because of containing; In stomach and small intestine, almost can not be digested and assimilated, and it mainly is to embody through the proliferation function to intestinal beneficial bacterium crowds such as Bacillus acidi lactici, Bifidobacteriums to human body beneficial's physiological function.Bacillus acidi lactici and Bifidobacterium can produce a series of glycosidases in the large intestine enteron aisle, the enzyme of existing cut-out cottonseed compound sugar sugar glycosidic bond also has the enzyme of hydrolysis interoside key.With Bifidobacterium, Bacillus acidi lactici is that the archenteric flora of advantage is optionally to the utilization of fermenting of cottonseed compound sugar; Make the speed of growth of Bifidobacterium and Bacillus acidi lactici accelerate; Quantity increases, and pernicious bacteria is difficult to utilize the cottonseed compound sugar simultaneously, and quantity reduces; Form this those long healthy gut flora environment that disappear, thereby bring a series of useful influence to human body.(1). impel Bifidobacterium propagation, regulate gut flora.(2). regulate the P H value of enteron aisle, suppressed growth of harmful intestinal tract bacteria, thereby suppress endotoxin, alleviate burden of liver.(3). promote bowel movement, improve the nutrient absorption rate, prevent constipation.(4). synthetic vitamin increases the needed nutriments of growth of animal such as B family vitamin (B1, B2, B6, folic acid etc.), vitamin K, niacin and amino acid.(5). delay organism aging process, enhancing body immunity.(6). improve the absorptivity of ferrous iron, calcium and vitamin D.(7). produce SCFA, reduce cholesterol, improve lipid-metabolism.
A research of Japan shows; Healthy subjects is absorbed 10g cottonseed compound sugar every day; The intestinal bifidobacteria proportion can rise to 58.2%～80.1% by original 15%; Can find out that from above function the cottonseed compound sugar is a kind of functional oligose with fine health-care effect, be the Bifidobacterium from cottonseed, the super nutritive agent of Bacillus acidi lactici.
A kind of raw produce with high added value that the cottonseed compound sugar is in the cottonseed to be rich in, Ministry of Health of the People's Republic of China's 2010 No. 3 literary composition approval cottonseed compound sugar is a new resource food, demands our development and use urgently.
How the above-mentioned raw materials material composition is effectively combined, make it to form, bring into play better function, and impel the absorption of human body utilization, then be still and need the technical task that experimental study solves badly.
Summary of the invention
Technical problem to be solved by this invention provides a kind of special populations such as endocrine Nutrition and Metabolism functional disturbance (diabetes), high fat of blood, hypertension, intestines and stomach inflammation, atherosclerotic, tumor disease practical instant tea--sweet tea of compound sugar pseudo-ginseng and preparation method and correlated product production method of being suitable for.
For solving the problems of the technologies described above; The present invention provides the sweet tea raw material of a kind of new type natural sweet tea of compound sugar pseudo-ginseng one by one; Its characteristic is by weight ratio sanchi leaf/flower extract 10%-35%; Sweet tea extract 5%-30%, folium cortex eucommiae concentrated extract 10%-30% and cottonseed compound sugar 10%--45% are as constituent.
Said sanchi leaf/flower extract contains the notoginseng total saponin composition more than 20%; Said sweet tea extract contains the sweet tea flavones more than 15%, and said folium cortex eucommiae concentrated extract contains the chlorogenic acid more than 20%.
The said sweet tea of the sweet tea of described compound sugar pseudo-ginseng is natural sweet taste plant Fagaceae oak plant Pasania cuspidata (lithocarpus polystachyus Rehd) Wild sweet tea.
The present invention also provides the preparation method of the sweet tea of a kind of said compound sugar pseudo-ginseng, it is characterized in that may further comprise the steps:
Step 1; With said sanchi leaf/flower extract, sweet tea extract, folium cortex eucommiae concentrated extract respectively after low temperature drying dehydration; Under normal temperature, gnotobasis condition; With the extract dry powder determination of raw material component content that makes, mistake 100 mesh sieves, fully mix, leave standstill, make the sweet tea flavones of notoginseng total saponin, sweet tea extract of sanchi leaf/flower extract, the chlorogenic acid active ingredient in the folium cortex eucommiae concentrated extract be combined into molecule group;
Step 2 is fully mixed the mixture that obtains step 1, is granulated with cottonseed compound sugar composition again, promptly obtains the sweet tea raw material of compound sugar pseudo-ginseng thing.
With the sweet tea raw material of the compound sugar pseudo-ginseng thing that makes, process granula, capsule, three kinds of formulation products of tablet by required formulation process.
The present invention is on the experiment basis of associated biomolecule composition of raw material, functional character, through demonstration, experimental study and the new special tea product that forms.The sweet tea material products of compound sugar pseudo-ginseng can effectively be regulated the human body endocrinopathy; The enhances human body immunity function; Regulate the enteral nutritional support metabolism, have dietary function value aspect the special populations such as prevention, adjuvant therapy of diabetes, high fat of blood, hypertension, intestines and stomach inflammation, atherosclerotic, tumor disease.
The specific embodiment
The sweet tea of compound sugar pseudo-ginseng is by weight ratio sanchi leaf/flower extract 10%-35%, sweet tea extract 5%-30%, and folium cortex eucommiae concentrated extract 10%-30% and cottonseed compound sugar 10%--45% are as constituent.Wherein, sanchi leaf/flower extract contains the notoginseng total saponin composition more than 20%; Sweet tea extract contains the sweet tea flavones more than 15%, and the folium cortex eucommiae concentrated extract contains the chlorogenic acid more than 20%.The sweet tea preparation method of practical implementation compound sugar pseudo-ginseng is: with said sanchi leaf/flower extract, Pasania cuspidata sweet tea extract, folium cortex eucommiae concentrated extract respectively after low temperature drying dehydration; Under normal temperature, gnotobasis condition; With the extract dry powder determination of raw material component content that makes, mistake 100 mesh sieves; Fully mix, leave standstill, make active ingredients such as the notoginseng total saponin in its sanchi leaf/flower extract, Pasania cuspidata sweet tea extract, the folium cortex eucommiae concentrated extract, sweet tea flavones, chlorogenic acid be combined into molecule group; The mixture that obtains is fully mixed, granulates with cottonseed compound sugar composition again, promptly obtain the sweet tea raw material of compound sugar pseudo-ginseng thing.With the sweet tea feed particles of compound sugar pseudo-ginseng that this preparation method processes, carry out aseptic process, metering, packing, be sealed to bag, process the granula bagged product.
Below enumerate the specific embodiment of the invention:
Instance 1, with the sweet tea constitutive material of compound sugar pseudo-ginseng contain the notoginseng total saponin composition more than 20% sanchi leaf/flower extract, contain the sweet tea flavones more than 15% the Pasania cuspidata sweet tea extract, contain the chlorogenic acid more than 20% the folium cortex eucommiae concentrated extract respectively after the low temperature drying dehydration; Under normal temperature, gnotobasis condition; Make the extract dry powder determination of raw material component content, mistake 100 mesh sieves that make; In production technology quality requirement preparation raw material (1): 10% sanchi leaf/flower extract, 15% sweet tea extract are fully mixed, leave standstill in the factory formula ratio with 30% folium cortex eucommiae concentration extraction, make active ingredients such as its notoginseng total saponin, sweet tea flavones, chlorogenic acid be combined into molecule group; (2): the mixture of (1) fully mixed, granulates with 45% cottonseed compound sugar composition more promptly obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product that is prepared into is carried out aseptic process, metering, packing, is sealed to bag, processes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, 60 bags of per one box-packed amounts (1.5gx60 bag), net content 90g meter.
Instance 2, with the sweet tea constitutive material of compound sugar pseudo-ginseng contain the notoginseng total saponin composition more than 20% sanchi leaf/flower extract, contain the sweet tea flavones more than 15% the Pasania cuspidata sweet tea extract, contain the chlorogenic acid more than 20% the folium cortex eucommiae concentrated extract respectively after the low temperature drying dehydration; Under normal temperature, gnotobasis condition; Make the extract dry powder determination of raw material component content, mistake 100 mesh sieves that make; In production technology quality requirement preparation raw material (1): 25% sanchi leaf/flower extract, 5% sweet tea extract are fully mixed, leave standstill in the factory formula ratio with 30% folium cortex eucommiae concentration extraction, make active ingredients such as its notoginseng total saponin, sweet tea flavones, chlorogenic acid be combined into molecule group; (2): the mixture of (1) fully mixed, granulates with 40% cottonseed compound sugar composition more promptly obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product that is prepared into is carried out aseptic process, metering, packing, is sealed to bag, processes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, 60 bags of per one box-packed amounts (1.5gx60 bag), net content 90g meter.
Instance 3, with the sweet tea constitutive material of compound sugar pseudo-ginseng contain the notoginseng total saponin composition more than 20% sanchi leaf/flower extract, contain the sweet tea flavones more than 15% the Pasania cuspidata sweet tea extract, contain the chlorogenic acid more than 20% the folium cortex eucommiae concentrated extract respectively after the low temperature drying dehydration; Under normal temperature, gnotobasis condition; Make the extract dry powder determination of raw material component content, mistake 100 mesh sieves that make; In production technology quality requirement preparation raw material (1): 25% sanchi leaf/flower extract, 20% sweet tea extract are fully mixed, leave standstill in the factory formula ratio with 10% folium cortex eucommiae concentration extraction, make active ingredients such as its notoginseng total saponin, sweet tea flavones, chlorogenic acid be combined into molecule group; (2): the mixture of (1) fully mixed, granulates with 45% cottonseed compound sugar composition more promptly obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product that is prepared into is carried out aseptic process, metering, packing, is sealed to bag, processes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, 60 bags of per one box-packed amounts (1.5gx60 bag), net content 90g meter.
Instance 4, with the sweet tea constitutive material of compound sugar pseudo-ginseng contain the notoginseng total saponin composition more than 20% sanchi leaf/flower extract, contain the sweet tea flavones more than 15% the Pasania cuspidata sweet tea extract, contain the chlorogenic acid more than 20% the folium cortex eucommiae concentrated extract respectively after the low temperature drying dehydration; Under normal temperature, gnotobasis condition; Make the extract dry powder determination of raw material component content, mistake 100 mesh sieves that make; In production technology quality requirement preparation raw material (1): 30% sanchi leaf/flower extract, 30% sweet tea extract are fully mixed, leave standstill in the factory formula ratio with 30% folium cortex eucommiae concentration extraction, make active ingredients such as its notoginseng total saponin, sweet tea flavones, chlorogenic acid be combined into molecule group; (2): the mixture of (1) fully mixed, granulates with 10% cottonseed compound sugar composition more promptly obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product that is prepared into is carried out aseptic process, metering, packing, is sealed to bag, processes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, 60 bags of per one box-packed amounts (1.5gx60 bag), net content 90g meter.
Instance 5, with the sweet tea constitutive material of compound sugar pseudo-ginseng contain the notoginseng total saponin composition more than 20% sanchi leaf/flower extract, contain the sweet tea flavones more than 15% the Pasania cuspidata sweet tea extract, contain the chlorogenic acid more than 20% the folium cortex eucommiae concentrated extract respectively after the low temperature drying dehydration; Under normal temperature, gnotobasis condition; Make the extract dry powder determination of raw material component content, mistake 100 mesh sieves that make; In production technology quality requirement preparation raw material (1): 25% sanchi leaf/flower extract, 15% sweet tea extract are fully mixed, leave standstill in the factory formula ratio with 30% folium cortex eucommiae concentration extraction, make active ingredients such as its notoginseng total saponin, sweet tea flavones, chlorogenic acid be combined into molecule group; (2): the mixture of (1) fully mixed, granulates with 30% cottonseed compound sugar composition more promptly obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product that is prepared into is carried out aseptic process, metering, packing, is sealed to bag, processes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, 60 bags of per one box-packed amounts (1.5gx60 bag), net content 90g meter.
Instance 6, with the sweet tea constitutive material of compound sugar pseudo-ginseng contain the notoginseng total saponin composition more than 20% sanchi leaf/flower extract, contain the sweet tea flavones more than 15% the Pasania cuspidata sweet tea extract, contain the chlorogenic acid more than 20% the folium cortex eucommiae concentrated extract respectively after the low temperature drying dehydration; Under normal temperature, gnotobasis condition; Make the extract dry powder determination of raw material component content, mistake 100 mesh sieves that make; In production technology quality requirement preparation raw material (1): 35% sanchi leaf/flower extract, 15% sweet tea extract are fully mixed, leave standstill in the factory formula ratio with 25% folium cortex eucommiae concentration extraction, make active ingredients such as its notoginseng total saponin, sweet tea flavones, chlorogenic acid be combined into molecule group; (2): the mixture of (1) fully mixed, granulates with 25% cottonseed compound sugar composition more promptly obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product that is prepared into is carried out aseptic process, metering, packing, is sealed to bag, processes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, 60 bags of per one box-packed amounts (1.5gx60 bag), net content 90g meter.
Instance 7, with the sweet tea constitutive material of compound sugar pseudo-ginseng contain the notoginseng total saponin composition more than 20% sanchi leaf/flower extract, contain the sweet tea flavones more than 15% the Pasania cuspidata sweet tea extract, contain the chlorogenic acid more than 20% the folium cortex eucommiae concentrated extract respectively after the low temperature drying dehydration; Under normal temperature, gnotobasis condition; Make the extract dry powder determination of raw material component content, mistake 100 mesh sieves that make; In production technology quality requirement preparation raw material (1): 15% sanchi leaf/flower extract, 30% sweet tea extract are fully mixed, leave standstill in the factory formula ratio with 30% folium cortex eucommiae concentration extraction, make active ingredients such as its notoginseng total saponin, sweet tea flavones, chlorogenic acid be combined into molecule group; (2): the mixture of (1) fully mixed, granulates with 25% cottonseed compound sugar composition more promptly obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product that is prepared into is carried out aseptic process, metering, packing, is sealed to bag, processes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, 60 bags of per one box-packed amounts (1.5gx60 bag), net content 90g meter.
Instance 8, with the sweet tea constitutive material of compound sugar pseudo-ginseng contain the notoginseng total saponin composition more than 20% sanchi leaf/flower extract, contain the sweet tea flavones more than 15% the Pasania cuspidata sweet tea extract, contain the chlorogenic acid more than 20% the folium cortex eucommiae concentrated extract respectively after the low temperature drying dehydration; Under normal temperature, gnotobasis condition; Make the extract dry powder determination of raw material component content, mistake 100 mesh sieves that make; In production technology quality requirement preparation raw material (1): 35% sanchi leaf/flower extract, 15% sweet tea extract are fully mixed, leave standstill in the factory formula ratio with 20% folium cortex eucommiae concentration extraction, make active ingredients such as its notoginseng total saponin, sweet tea flavones, chlorogenic acid be combined into molecule group; (2): the mixture of (1) fully mixed, granulates with 30% cottonseed compound sugar composition more promptly obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product that is prepared into is carried out aseptic process, metering, packing, is sealed to bag, processes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, 60 bags of per one box-packed amounts (1.5gx60 bag), net content 90g meter.
Instance 9, with the sweet tea constitutive material of compound sugar pseudo-ginseng contain the notoginseng total saponin composition more than 20% sanchi leaf/flower extract, contain the sweet tea flavones more than 15% the Pasania cuspidata sweet tea extract, contain the chlorogenic acid more than 20% the folium cortex eucommiae concentrated extract respectively after the low temperature drying dehydration; Under normal temperature, gnotobasis condition; Make the extract dry powder determination of raw material component content, mistake 100 mesh sieves that make; In production technology quality requirement preparation raw material (1): 20% sanchi leaf/flower extract, 10% sweet tea extract are fully mixed, leave standstill in the factory formula ratio with 25% folium cortex eucommiae concentration extraction, make active ingredients such as its notoginseng total saponin, sweet tea flavones, chlorogenic acid be combined into molecule group; (2): the mixture of (1) fully mixed, granulates with 45% cottonseed compound sugar composition more promptly obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product that is prepared into is carried out aseptic process, metering, packing, is sealed to bag, processes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, 60 bags of per one box-packed amounts (1.5gx60 bag), net content 90g meter.
Instance 10, with the sweet tea constitutive material of compound sugar pseudo-ginseng contain the notoginseng total saponin composition more than 20% sanchi leaf/flower extract, contain the sweet tea flavones more than 15% the Pasania cuspidata sweet tea extract, contain the chlorogenic acid more than 20% the folium cortex eucommiae concentrated extract respectively after the low temperature drying dehydration; Under normal temperature, gnotobasis condition; Make the extract dry powder determination of raw material component content, mistake 100 mesh sieves that make; In production technology quality requirement preparation raw material (1): 20% sanchi leaf/flower extract, 15% sweet tea extract are fully mixed, leave standstill in the factory formula ratio with 30% folium cortex eucommiae concentration extraction, make active ingredients such as its notoginseng total saponin, sweet tea flavones, chlorogenic acid be combined into molecule group; (2): the mixture of (1) fully mixed, granulates with 35% cottonseed compound sugar composition more promptly obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product that is prepared into is carried out aseptic process, metering, packing, is sealed to bag, processes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, 60 bags of per one box-packed amounts (1.5gx60 bag), net content 90g meter.
The sweet tea of compound sugar pseudo-ginseng of the present invention is special instant tea goods; Its prescription theory of constitution science, reasonable; The sweet tea Study on Functional of compound sugar pseudo-ginseng active component is extensive, and its material products can effectively be regulated human body endocrinopathy, enhances human body immunity function; Regulate the enteral nutritional support metabolism, be fit to special populations such as prevention, adjuvant therapy of diabetes, high fat of blood, hypertension, intestines and stomach inflammation, atherosclerotic, tumor disease and use.
With the foregoing description be: every day 2 times, sooner or later drink each 1 bag in the interior sweet tea-drinking use of compound sugar pseudo-ginseng of the present invention method; Get 1 bag of these article before the meal, put into and drink after the cup temperature of falling 200lm--300lm boiling water is waited to dissolve.
Claims (5)
1. sweet tea of compound sugar pseudo-ginseng, its characteristic is by weight ratio sanchi leaf/flower extract 10%-35%, sweet tea extract 5%-30%, and folium cortex eucommiae concentrated extract 10%-30% and cottonseed compound sugar 10%--45% are as constituent.
2. the sweet tea constitutive material of compound sugar pseudo-ginseng according to claim 1, said sanchi leaf/flower extract contains the notoginseng total saponin composition more than 20%; Said sweet tea extract contains the sweet tea flavones more than 15%, and said folium cortex eucommiae concentrated extract contains the chlorogenic acid more than 20%.
3. the said sweet tea of the sweet tea of compound sugar pseudo-ginseng according to claim 1 and 2 is natural sweet taste plant Fagaceae oak plant Pasania cuspidata Wild sweet tea.
4. preparation method according to claim 1 or the sweet tea of 2 or 3 described compound sugar pseudo-ginseng is characterized in that may further comprise the steps:
Step 1; With said sanchi leaf/flower extract, sweet tea extract, folium cortex eucommiae concentrated extract respectively after low temperature drying dehydration; Under normal temperature, gnotobasis condition; With the extract dry powder determination of raw material component content that makes, mistake 100 mesh sieves, fully mix, leave standstill, make the sweet tea flavones of notoginseng total saponin, sweet tea extract of sanchi leaf/flower extract, the chlorogenic acid active ingredient in the folium cortex eucommiae concentrated extract be combined into molecule group;
Step 2 is fully mixed the mixture that obtains step 1, is granulated with cottonseed compound sugar composition again, promptly obtains the sweet tea raw material of compound sugar pseudo-ginseng thing.
5. the preparation method of the sweet tea of compound sugar pseudo-ginseng according to claim 4 is characterized in that further comprising the steps of: with the sweet tea raw material of the compound sugar pseudo-ginseng thing that makes, process granula, capsule, three kinds of formulation products of tablet by required formulation process.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113647482A (en) * | 2021-08-19 | 2021-11-16 | 紫物境界(赤壁)茶业有限公司 | Cold-dried sweet osmanthus flower green tea and preparation method thereof |
| CN116762881A (en) * | 2023-02-13 | 2023-09-19 | 贵州斛多福食品有限公司 | Litsea coreana sweet tea and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101543247A (en) * | 2008-03-27 | 2009-09-30 | 胡应祥 | Wild sweet tea series products and manufacturing method thereof |
| CN101874875A (en) * | 2010-05-26 | 2010-11-03 | 唐桂德 | Chinese medicinal tea for treating hypertension, hyperlipoidemia and high blood viscosity and preparation method thereof |
| CN102113584A (en) * | 2011-03-15 | 2011-07-06 | 黄选明 | Health preserving tea |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101543247A (en) * | 2008-03-27 | 2009-09-30 | 胡应祥 | Wild sweet tea series products and manufacturing method thereof |
| CN101874875A (en) * | 2010-05-26 | 2010-11-03 | 唐桂德 | Chinese medicinal tea for treating hypertension, hyperlipoidemia and high blood viscosity and preparation method thereof |
| CN102113584A (en) * | 2011-03-15 | 2011-07-06 | 黄选明 | Health preserving tea |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113647482A (en) * | 2021-08-19 | 2021-11-16 | 紫物境界(赤壁)茶业有限公司 | Cold-dried sweet osmanthus flower green tea and preparation method thereof |
| CN116762881A (en) * | 2023-02-13 | 2023-09-19 | 贵州斛多福食品有限公司 | Litsea coreana sweet tea and preparation method thereof |
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