CN103180727B - 具有保护柱的色谱系统 - Google Patents

具有保护柱的色谱系统 Download PDF

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Publication number
CN103180727B
CN103180727B CN201180051833.5A CN201180051833A CN103180727B CN 103180727 B CN103180727 B CN 103180727B CN 201180051833 A CN201180051833 A CN 201180051833A CN 103180727 B CN103180727 B CN 103180727B
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CN
China
Prior art keywords
principal post
guard column
guard
chromatography resin
column
Prior art date
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Application number
CN201180051833.5A
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English (en)
Chinese (zh)
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CN103180727A (zh
Inventor
K.拉基
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Cytiva Sweden AB
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GE Healthcare Bio Sciences AB
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Publication date
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Publication of CN103180727A publication Critical patent/CN103180727A/zh
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
CN201180051833.5A 2010-10-27 2011-10-24 具有保护柱的色谱系统 Active CN103180727B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1051116-0 2010-10-27
SE1051116 2010-10-27
PCT/SE2011/051254 WO2012057676A1 (en) 2010-10-27 2011-10-24 Chromatography system with guard columns

Publications (2)

Publication Number Publication Date
CN103180727A CN103180727A (zh) 2013-06-26
CN103180727B true CN103180727B (zh) 2015-12-16

Family

ID=45994166

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201180051833.5A Active CN103180727B (zh) 2010-10-27 2011-10-24 具有保护柱的色谱系统

Country Status (5)

Country Link
US (3) US20130213884A1 (https=)
EP (1) EP2633306B1 (https=)
JP (1) JP5879357B2 (https=)
CN (1) CN103180727B (https=)
WO (1) WO2012057676A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102014010353B4 (de) 2014-07-10 2024-09-12 Sartorius Stedim Biotech Gmbh Vorrichtung, Verwendung dieser Vorrichtung und Verfahren für die Stofftrennung mit verbesserter Ausnutzung der Kapazität chromatographischer Medien
GB201511463D0 (en) 2015-06-30 2015-08-12 Ge Healthcare Bio Sciences Ab Improvements in and relating to fluid path networks
US11835501B2 (en) * 2015-07-13 2023-12-05 Sartorius Stedim Chromatography Systems Ltd. Optimizing operating binding capacity for a multiple column chromatography process
GB201517282D0 (en) * 2015-09-30 2015-11-11 Ge Healthcare Bio Sciences Ab A chromatography system and a method therefor
JP6206468B2 (ja) * 2015-11-11 2017-10-04 ダイキン工業株式会社 スクロール圧縮機
GB201602938D0 (en) * 2016-02-19 2016-04-06 Ucb Biopharma Sprl Protein purification
MX2021001915A (es) * 2018-08-17 2021-05-31 Regeneron Pharma Metodo y sistema de cromatografia para determinar la cantidad y pureza de una proteina multimerica.
GB201909274D0 (en) * 2019-06-27 2019-08-14 Ge Healthcare Bio Sciences Ab Method in bioprocess purification system
WO2020258515A1 (zh) * 2019-06-28 2020-12-30 浙江大学 多柱连续流层析设计及分析的方法
CN115398223A (zh) * 2020-04-15 2022-11-25 沃特世科技公司 用于尺寸排阻色谱分离的保护柱构造

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60142251A (ja) * 1983-12-29 1985-07-27 Shimadzu Corp ガ−ドカラム充てん法
CN2094745U (zh) * 1991-06-22 1992-01-29 中国科学院大连化学物理研究所 一种带保护柱的高效液相色谱柱
US5651885A (en) * 1994-04-15 1997-07-29 Schick; Hans G. Column for liquid chromatography
WO2002029401A1 (de) * 2000-10-02 2002-04-11 Merck Patent Gmbh Verfahren und system zur methodenoptimierung in der chromatographie
WO2009023268A1 (en) * 2007-08-16 2009-02-19 Alltech Associates Inc. Chromatography column assemblies

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
US4826603A (en) * 1986-09-09 1989-05-02 United States Of America As Represented By The Secretary Of The Air Force Hydrocarbon group-type analyzer system
US4851355A (en) * 1987-06-05 1989-07-25 Hayes Jr Paul C Hydrocarbon group-type analyzer system
JP3053131B2 (ja) * 1991-09-17 2000-06-19 株式会社日立製作所 ガードカラムを備えた高速液体クロマトグラフ
JPH06511084A (ja) * 1991-09-30 1994-12-08 パーセプティブ　バイオシステムズ　インコーポレイテッド 蛋白のクロマトグラフィーシステム
EP0835446B1 (en) * 1995-06-26 2003-04-09 Perseptive Biosystems, Inc. High speed, automated, continuous flow, multi-dimensional molecular selection and analysis
US7691645B2 (en) * 2001-01-09 2010-04-06 Agilent Technologies, Inc. Immunosubtraction method
JP3996550B2 (ja) * 2003-05-28 2007-10-24 株式会社日立ハイテクノロジーズ アミノ酸分析装置
JP4504721B2 (ja) * 2004-04-07 2010-07-14 オルガノ株式会社 液体クロマトグラフィー装置
US20060157647A1 (en) * 2005-01-18 2006-07-20 Becton, Dickinson And Company Multidimensional liquid chromatography/spectrometry
US7520920B1 (en) * 2005-03-04 2009-04-21 Griffin Analytical Technologies Guard columns for gas chromatographs and gas chromatograph-mass spectrometers
EP2066419B1 (en) * 2006-09-29 2015-11-11 GE Healthcare Bio-Sciences AB Chromatography ligand comprising domain c from staphyloccocus aureus protein a for antibody isolation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60142251A (ja) * 1983-12-29 1985-07-27 Shimadzu Corp ガ−ドカラム充てん法
CN2094745U (zh) * 1991-06-22 1992-01-29 中国科学院大连化学物理研究所 一种带保护柱的高效液相色谱柱
US5651885A (en) * 1994-04-15 1997-07-29 Schick; Hans G. Column for liquid chromatography
WO2002029401A1 (de) * 2000-10-02 2002-04-11 Merck Patent Gmbh Verfahren und system zur methodenoptimierung in der chromatographie
WO2009023268A1 (en) * 2007-08-16 2009-02-19 Alltech Associates Inc. Chromatography column assemblies

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Characteristics and applications of a new high-performance liquid chromatography guard column;Mark Capparella et al.;《Journal of Chromatography A》;19950203;第691卷(第1-2期);141-450 *
新型高效液相色谱柱的保护柱;于亿年 等;《色谱》;19890501;第7卷(第2期);104-106 *

Also Published As

Publication number Publication date
JP5879357B2 (ja) 2016-03-08
CN103180727A (zh) 2013-06-26
EP2633306B1 (en) 2016-03-23
JP2014501911A (ja) 2014-01-23
US20180340917A1 (en) 2018-11-29
US20210080434A1 (en) 2021-03-18
EP2633306A1 (en) 2013-09-04
EP2633306A4 (en) 2014-10-08
US20130213884A1 (en) 2013-08-22
WO2012057676A1 (en) 2012-05-03

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