CN103041165B - 一种治疗快速减肥性脂肪肝的中药 - Google Patents
一种治疗快速减肥性脂肪肝的中药 Download PDFInfo
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Abstract
本发明涉及一种治疗快速减肥性脂肪肝的中药，由以下重量配比的药材制备而成：白术12份、桂枝6份、夏天无12份、玉竹9份、赤小豆30份、韭菜子4份、九里香8份。临床实验证明，本发明能够安全有效治疗快速减肥性脂肪肝。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗快速减肥性脂肪肝的中药。
背景技术
脂肪肝是一种多病因引起的脂肪在肝细胞内异常积累的病理状态。正常人的肝内总脂肪量，约占肝重的5%，内含磷脂、甘油三酯、脂酸、胆固醇及胆固醇脂。脂肪量超过5%为轻度脂肪肝，超过10%为中度脂肪肝，超过25% 为重度脂肪肝。当肝内总脂肪量超过30%时，用B超才能检查出来，被确诊为“脂肪肝”。而平时所说的脂肪肝患者，总脂量可达40%～50%，有些达60%以上。脂肪肝久治不愈则会发展成脂肪性肝炎、脂肪性肝硬化。
脂肪肝按病因可分为： 1、肥胖性脂肪肝2、酒精性脂肪肝3、快速减肥性脂肪肝4、营养不良性脂肪肝5、糖尿病脂肪肝6、药物性脂肪肝7、妊娠脂肪肝8、其他疾病引起的脂肪肝。
到目前为止，西药尚无防治脂肪肝的有效药物，以中药长期调理性的治疗最好。但很多中药在治疗快速减肥性脂肪肝的同时，会造成体重反弹或者上火出痘，患者接受度并不好。
本发明中药所涉及药材的研究现状如下：
白术【来源】本品为菊科植物白术Atractylodes macrocephala Koidz.的干燥根茎。冬季下部叶枯黄、上部叶变脆时采挖，除去泥沙，烘干或晒干，再除去须根。【性味】苦、甘，温。【归经】归脾、胃经。【功能主治】健脾益气，燥湿利水，止汗，安胎。用于脾虚食少，腹胀泄泻，痰饮眩悸，水肿，自汗，胎动不安。土白术健脾，和胃，安胎。用于脾虚食少，泄泻便溏，胎动不安。【用法用量】 6～12g。
桂枝【来源】本品为樟科植物肉桂 Cinnamomum cassia Presl的干燥嫩枝。春、夏二季采收，除去叶，晒干，或切片晒干。【性味】辛、甘，温。【归经】归心、肺、膀胱经。【功能主治】发汗解肌，温通经脉，助阳化气，平冲降气。用于风寒感冒，脘腹冷痛，血寒经闭，关节痹痛，痰饮，水肿，心悸，奔豚。【用法用量】 3～9g。
夏天无【来源】本品为罂粟科植物伏生紫堇Corydalis decumbens （Thunb.）Pers. 的干燥块茎。春季或初夏出苗后采挖，除去茎、叶及须根，洗净，干燥。【性味】苦、微辛，温。【归经】归肝经。【功能主治】活血通络，行气止痛。用于中风偏瘫，跌扑损伤，风湿性关节炎，坐骨神经痛。【用法用量】 6～12g，研末分3次服。
玉竹【来源】本品为百合科植物玉竹Polygonatum odoratum （Mill.）Druce的干燥根茎。秋季采挖，除去须根，洗净，晒至柔软后，反复揉搓、晾晒至无硬心，晒干；或蒸透后，揉至半透明，晒干。【炮制】除去杂质，洗净，润透，切厚片或段，干燥。【性味】甘，微寒。【归经】归肺、胃经。【功能主治】养阴润燥，生津止渴。用于肺胃阴伤，燥热咳嗽，咽干口渴，内热消渴。【用法用量】 6～12g。
赤小豆【来源】本品为豆科植物赤小豆Phaseolus calcaratus Roxb. 或赤豆Phaseolus angularis Wight的干燥成熟种子。秋季果实成熟而未开裂时拔取全株，晒干，打下种子，除去杂质， 再晒干。【性味】甘、酸，平。【归经】归心、小肠经。【功能主治】利水消肿，解毒排脓。用于水肿胀满，脚气肢肿，黄疸尿赤，风湿热痹，痈肿疮毒，肠痈腹痛。【用法用量】 9～30g。外用适量，研末调敷。
韭菜子【来源】本品为百合科植物韭菜Allium tuberosum Rottl. 的干燥成熟种子。秋季果实成熟时采收果序，晒干，搓出种子，除去杂质。【性味】辛、甘，温。【归经】归肝、肾经。【功能主治】温补肝肾，壮阳固精。用于阳痿遗精，腰膝酸痛，遗尿尿频，白浊带下。【用法用量】 3～9g。
九里香【来源】本品为芸香科植物九里香Murraya exotica L.和千里香Murraya paniculata （L.）xJack的干燥叶和带叶嫩枝。全年均可采收，除去老枝，阴干。【炮制】除去杂质，切碎。【性味】辛、微苦，温；有小毒。【功能主治】行气止痛，活血散瘀。用于胃痛，风湿痹痛；外治牙痛，跌扑肿痛，虫蛇咬伤。【用法用量】 6～12g。外用鲜品适量，捣烂敷患处。
发明内容
本发明旨在提供一种治疗快速减肥性脂肪肝的中药，通过选择合适的药材及其配比，达到安全有效治愈快速减肥性脂肪肝的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗快速减肥性脂肪肝的中药，其特征在于，由以下重量配比的药材制备而成：白术12份、桂枝6份、夏天无12份、玉竹9份、赤小豆30份、韭菜子4份、九里香8份。
下面结合中医理论来说明本发明的有益效果：
发明人认为，快速减肥性脂肪肝是由于突然性肝脏脂肪代谢负担过大，而导致痰湿阻滞。治疗应重在健脾利湿、益气活血。本发明运用：白术健脾燥湿，夏天无活血行气，九里香行气活血散瘀，赤小豆解毒排脓。同时采用韭菜子温补肝肾，桂枝温通经脉，助阳化气，达到轻身燃脂的效果，又使用玉竹养阴润燥，滋养肌肤。诸药合用，在治疗快速减肥性脂肪肝的同时，轻身健体，排毒养颜。想患者之所想，受到患者广泛地的接受与好评。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2010年6月-2011年10月间共收集73例诊断为快速减肥性脂肪肝的门诊患者，年龄15-36岁，病程0.5-6年。随机分为：治疗组50例，空白组23例。两组年龄、病情等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗组口服本发明按照具体实施例1制得的胶囊，早晚各一次。疗程15天。
2.2空白组口服安慰剂胶囊，早晚各一次。疗程15天。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常。好转：临床症状减轻，实验室检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 不良反应例 | 总有效率(%) |
| 治疗组 | 50 | 5（10%） | 37 | 8(16%) | 0 | 84% |
| 空白组 | 23 | 0 | 3 | 20（87%） | 0 | 13% |
可见，本发明制得的药物能够安全有效治疗快速减肥性脂肪肝。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取：白术12克、桂枝6克、夏天无12克、玉竹9克、赤小豆30克、韭菜子4克、九里香8克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗快速减肥性脂肪肝。口服，每日分早晚两次服用。
具体实施例2
称取：白术12克、桂枝6克、夏天无12克、玉竹9克、赤小豆30克、韭菜子4克、九里香8克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，浓缩，干燥，粉碎，即得符合正常成人1天用量的散剂。
用于治疗快速减肥性脂肪肝。口服，每日分早晚两次服用。
具体实施例3
称取：白术12克、桂枝6克、夏天无12克、玉竹9克、赤小豆30克、韭菜子4克、九里香8克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，干燥，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人1天用量的颗粒剂。
用于治疗快速减肥性脂肪肝。口服，每日分早晚两次服用。
Claims (1)
1.一种治疗快速减肥性脂肪肝的中药，其特征在于，由以下重量配比的药材制备而成：白术12份、桂枝6份、夏天无12份、玉竹9份、赤小豆30份、韭菜子4份、九里香8份。
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Non-Patent Citations (2)
| Title |
|---|
| 刘桂林.脂肪肝中药治疗概述.《海峡药学》.2009,第21卷(第1期),第133-134页. |
| 脂肪肝中药治疗概述;刘桂林;《海峡药学》;20091231;第21卷(第1期);第133-134页 * |
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