CN103041028A - Traditional Chinese medicine composition for treating acne - Google Patents
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Abstract
The invention discloses a traditional Chinese medicine composition for treating acne. The traditional Chinese medicine composition comprises rhizoma coptidis, radix scutellariae, radix rehmanniae, radix angelicae sinensis, radix sophorae flavescentis, cynanchum paniculatum, cortex dictamni, honeysuckle flowers and licorice roots; and the traditional Chinese medicine composition is characterized by comprising the following Chinese medicinal herbs in parts by mass: 5-20 parts of rhizoma coptidis, 5-25 parts of radix scutellariae, 10-30 parts of radix rehmanniae, 8-30 parts of radix angelicae sinensis, 5-30 parts of radix sophorae flavescentis, 5-30 parts of cynanchum paniculatum, 5-25 parts of cortex dictamni, 10-30 parts of honeysuckle flowers, and 5-15 parts of licorice roots. The traditional Chinese medicine composition has the advantages that through the reasonable compatibility of various Chinese medicinal herbs, and by adopting a special formula of a dual-monarch drug, the traditional Chinese medicine composition meets the compatibility requirements of assistant and guide Chinese medicinal herbs, and achieves a good effect that the cure rate is 52.5% and the total effective rate is 92.5% under limited sample conditions. The traditional Chinese medicine composition disclosed by the invention is rigorous and scientific in formula compatibility; and the Chinese medicinal herbs, either monomers or compositions, produce no toxic or side effect under reasonable application conditions, thereby providing a new therapeutic schedule for the exploration of acne treatment.
Description
Technical field
The invention belongs to the traditional field of Chinese herbal medicine technology of China, specially refer to a kind of Chinese medicine composition of Acne treatment.
Background technology
Acne is because the obstruction of cortex glandular tube and pore, causes the pilosebaceous chronic inflammatory disease due to freely of skin outflow.The traditional Chinese medical science is called " acne ", " whelk ", " skin sore ".Total incidence accounts for the 20-24% of population, especially is apt to occur in the adolescence men and women, is mainly in the abundant position of the sebaceous gland such as face, chest, back, the part has rash to itch and pain, the course of disease is permanent and slowly, the continued several years that has, badly influences patient's face and physical and mental health.Doctor trained in Western medicine thinks that its morbidity is main and sex hormone level, sebaceous gland are secreted in a large number, propionibacterium acnes propagation, the factor analysis such as the dyskeratosis of hair follicle cortex gland conduit and inflammation.The traditional Chinese medical science is thought the pathogensis of primary disease: plain body sun heat is contained partially, and the lung meridian intrinsic heat is subjected to ailment said due to cold or exposure again, and is stifling facial and send out; The pungent delicious food savoury of surfeit helps heat of wetting, damp-heat gluing each other, upper steaming face and causing; Deficiency of spleen-QI, dysfunction of the spleen in transportation and transformation stops in the turbid damp, strongly fragrant heat-transformation of a specified duration, the bright body fluid of heat is fried in shallow oil and is smelt expectorant, and the wet hot phlegm stasis of blood stagnates skin and sends out.According to this pathogenesis, the present inventor has done in earnest research, and the morbidity of analyzing acne be unable to do without " wetting ", " heat " two large principal elements, and then has proposed goal of the invention of the present invention.
Summary of the invention
Goal of the invention of the present invention is according to above-mentioned pathogenesis of acne mechanism, and according to the theory of Chinese Chinese medicine, it is main drawing up heat clearing and damp drying, holds concurrently with eliminating fire and detoxication, and removing heat from blood and promoting blood circulation dispels the wind and one group of Chinese medicine composition of Acne treatment.A kind of Chinese medicine composition of Acne treatment namely is provided.
Technical solution of the present invention is to realize like this, the Chinese medicine composition of this Acne treatment, have Rhizoma Coptidis, Radix Scutellariae, the Radix Rehmanniae, Radix Angelicae Sinensis, Radix Sophorae Flavescentis, Radix Cynanchi Paniculati, Cortex Dictamni, Flos Lonicerae and Radix Glycyrrhizae, it is characterized in that each Chinese medicine material forms according to following mass fraction compatibility
Rhizoma Coptidis 5-20 part, Radix Scutellariae 5-25 part, Radix Rehmanniae 10-30 part, Radix Angelicae Sinensis 8-30 part, Radix Sophorae Flavescentis 5-30 part, Radix Cynanchi Paniculati 5-30 part, Cortex Dictamni 5-25 part, Flos Lonicerae 10-30 part, Radix Glycyrrhizae 5-15 part.
By optimizing, each Chinese medicine material of said Rhizoma Coptidis, Radix Scutellariae, the Radix Rehmanniae, Radix Angelicae Sinensis, Radix Sophorae Flavescentis, Radix Cynanchi Paniculati, Cortex Dictamni, Flos Lonicerae and Radix Glycyrrhizae forms according to following mass fraction compatibility:
Rhizoma Coptidis 10-15 part, Radix Scutellariae 10-20 part, Radix Rehmanniae 10-20 part, Radix Angelicae Sinensis 10-20 part, Radix Sophorae Flavescentis 10-20 part, Radix Cynanchi Paniculati 10-20 part, Cortex Dictamni 10-20 part, Flos Lonicerae 15-20 part, Radix Glycyrrhizae 8-15 part.
Through further optimizing, each Chinese medicine material of said Rhizoma Coptidis, Radix Scutellariae, the Radix Rehmanniae, Radix Angelicae Sinensis, Radix Sophorae Flavescentis, Radix Cynanchi Paniculati, Cortex Dictamni, Flos Lonicerae and Radix Glycyrrhizae forms according to following mass fraction compatibility:
Rhizoma Coptidis 12-15 part, Radix Scutellariae 15-20 part, Radix Rehmanniae 15-20 part, Radix Angelicae Sinensis 15-20 part, Radix Sophorae Flavescentis 15-20 part, Radix Cynanchi Paniculati 15-20 part, Cortex Dictamni 15-20 part, Flos Lonicerae 15-20 part, Radix Glycyrrhizae 10-15 part.
According to Chinese medicine and modern " Chinese pharmacopoeia record, the below above-mentioned all flavor Chinese herbal medicine of explanation.
Rhizoma Coptidis.Meridian distribution of property and flavor: (root) hardship, cold, nontoxic.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Function cures mainly: heat clearing and damp drying, eliminating fire and detoxication.Usage and dosage: decoction, 2～5 grams.
Radix Scutellariae.Meridian distribution of property and flavor: hardship, cold.Return lung, gallbladder, spleen, stomach, large intestine, small intestine meridian.Function cures mainly: heat clearing and damp drying, and eliminating fire and detoxication, hemostasis, antiabortive, blood pressure lowering.Usage and dosage: 3～9g.
The Radix Rehmanniae.Meridian distribution of property and flavor: sweet, cold.GUIXIN, liver, kidney channel.Function cures mainly: Radix Rehmanniae clearing away heat and cooling blood, yin nourishing is promoted the production of body fluid.Usage and consumption: 9～15 grams.
Radix Angelicae Sinensis.Meridian distribution of property and flavor: sweet in the mouth; Hot; Bitter; Warm in nature.Return liver, the heart, spleen channel.Function cures mainly: tonifying blood and regulating menstruation; Promoting blood circulation and stopping pain; Loosening bowel to relieve constipation.Usage and dosage: for oral administration: fry in shallow oil soup, the 6-12 gram; Or enter ball, loose; Or infusing drugs in wine; Or deposited cream.
Radix Sophorae Flavescentis.Meridian distribution of property and flavor: bitter in the mouth; Cold in nature.Return liver, kidney, large intestine, small intestine meridian, heart channel, urinary bladder channel.Function cures mainly: heat clearing and damp drying; Parasite killing (external), diuresis.Usage and dosage: 4.5～9g.
Radix Cynanchi Paniculati.Meridian distribution of property and flavor: suffering, temperature.Return liver, stomach warp.Function cures mainly: the removing dampness of dispeling the wind, antalgesic-antipruritic.Usage and dosage: 3～12g, entering decoct should be rear lower.
Cortex Dictamni.Meridian distribution of property and flavor: hardship; Salty; Cold.Return spleen channel, lung meridian, small intestine meridian, stomach warp, urinary bladder channel.Function cures mainly: heat clearing and damp drying; Dispelling wind for relieving itching; Detoxifcation.Rubella due to the wind heat noxious dampness; Eczema; Scabies; Jaundice; Damp-heat arthralgia.Usage and dosage: for oral administration: fry in shallow oil soup, the 6-15 gram; Or enter ball, loose.
Flos Lonicerae.Meridian distribution of property and flavor: sweet, little hardship, delicate fragrance, suffering, cold.Return lung, stomach, the heart, large intestine channel.Function cures mainly: dispelling wind-heat, heat-clearing and toxic substances removing.Consumption: crude drug 10～30 grams; Fry medicine 10～20 grams; Charcoal drug 10～15 grams.
Radix Glycyrrhizae.Meridian distribution of property and flavor: sweet in the mouth, property is flat, and is nontoxic.Return 12 warps.Function cures mainly: detoxifcation is arranged, eliminate the phlegm, pain relieving, spasmolytic be so that the pharmacological action such as anticancer.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Usage and dosage: 1.5～9g.
In the said medicine combination, Rhizoma Coptidis, Radix Scutellariae are monarch drug altogether, and the two is the property of bitter cold, kind middle burnt stomach-fire, the clear damp-heat in middle-JIAO of rushing down of Rhizoma Coptidis, Radix Scutellariae rushes down part of the body cavity above the diaphragm housing the heart and lungs lung-fire, clearing away lung-heat partially, Rhizoma Coptidis and Radix Scutellariae, similar temperament and speciality is respectively arranged is therefore the damp and hot benefit in two medicine synergism and Qinghua is aobvious.Flos Lonicerae heat-clearing and toxic substances removing, wind-dispelling heat-dissipating are ministerial drug.The Radix Sophorae Flavescentis heat clearing and damp drying, Radix Rehmanniae clearing away heat and cooling blood, Chinese Angelica blood replonishing is invigorated blood circulation, and it is adjuvant drug altogether that Radix Cynanchi Paniculati, Cortex Dictamni go wind antipruritic.The Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription is for making medicine.Full side harmoniously, the effect of play altogether heat clearing and damp drying, eliminating fire and detoxication, removing heat from blood and promoting blood circulation, dispeling the wind all there is good result for the acne of various pattern of syndrome.
Useful technique effect of the present invention is the reasonable compatibility through all flavor Chinese herbal medicine, adopt the special prescription of two monarchs drug, satisfy the Chinese medicine compatibility requirement of monarch, obtained cure rate 52.5% under limited sample condition, total effective rate reaches 92.5% good result.Prescription compatibility rigorous and scientific of the present invention, all Chinese herbal medicine materials be monomer or prescription no matter, and the generation that all has no side effect under rational service condition is for Acne treatment has been explored a new therapeutic scheme.
The specific embodiment
The below provides the embodiment of concrete quality composition, and the present invention is described in detail.Following amount is daily dose, one pair of every day.
Embodiment 1
Get: Rhizoma Coptidis 5 grams, Radix Scutellariae 5 grams, the Radix Rehmanniae 10 grams, Radix Angelicae Sinensis 8 grams, Radix Sophorae Flavescentis 5 grams, Radix Cynanchi Paniculati 5 grams, Cortex Dictamni 5 grams, Flos Lonicerae 10 grams, Radix Glycyrrhizae 5 grams.Sooner or later each once is decocted in water for oral dose.
Embodiment 2
Get: Rhizoma Coptidis 20 grams, Radix Scutellariae 25 grams, the Radix Rehmanniae 30 grams, Radix Angelicae Sinensis 30 grams, Radix Sophorae Flavescentis 30 grams, Radix Cynanchi Paniculati 30 grams, Cortex Dictamni 25 grams, Flos Lonicerae 30 grams, Radix Glycyrrhizae 15 grams.Sooner or later each once is decocted in water for oral dose.
Embodiment 3
Rhizoma Coptidis 10 grams, Radix Scutellariae 10 grams, the Radix Rehmanniae 15 grams, Radix Angelicae Sinensis 15 grams, Radix Sophorae Flavescentis 10 grams, Radix Cynanchi Paniculati 10 grams, Cortex Dictamni 10 grams, Flos Lonicerae 15 grams, Radix Glycyrrhizae 8 grams.Sooner or later each once is decocted in water for oral dose.
Embodiment 4
Rhizoma Coptidis 12 grams, Radix Scutellariae 15 grams, the Radix Rehmanniae 20 grams, Radix Angelicae Sinensis 20 grams, Radix Sophorae Flavescentis 15 grams, Radix Cynanchi Paniculati 15 grams, Cortex Dictamni 15 grams, Flos Lonicerae 20 grams, Radix Glycyrrhizae 10 grams.Sooner or later each once is decocted in water for oral dose.
Embodiment 5
Rhizoma Coptidis 15 grams, Radix Scutellariae 20 grams, the Radix Rehmanniae 25 grams, Radix Angelicae Sinensis 25 grams, Radix Sophorae Flavescentis 20 grams, Radix Cynanchi Paniculati 20 grams, Cortex Dictamni 20 grams, Flos Lonicerae 25 grams, Radix Glycyrrhizae 12 grams.Sooner or later each once is decocted in water for oral dose.
Embodiment 6
Rhizoma Coptidis 15 grams, Radix Scutellariae 20 grams, the Radix Rehmanniae 20 grams, Radix Angelicae Sinensis 20 grams, Radix Sophorae Flavescentis 20 grams, Radix Cynanchi Paniculati 20 grams, Cortex Dictamni 20 grams, Flos Lonicerae 20 grams, Radix Glycyrrhizae 10 grams.Sooner or later each once is decocted in water for oral dose.
The decocting method is as follows: above-mentioned all flavor Chinese herbal medicine are placed in the decoction pot, add clear water 500-600 milliliter, soaked 30-60 minute, then decoction pot was placed fire upper the boiled 3-5 of boiling of first big fire minute, then little fire keeps fluidized state in the decoction pot, 20-30 minute, make pot interior clear water and Chinese herbal medicine be mixed into medicine soup through decocting fully.Treat that decoction pot giving drugs into nose soup amount is the 150-200 milliliter, medicine soup is poured out.To pour the water of 500-600 milliliter in the decoction pot into again, repeat aforesaid process.After the medicine soup mixing with twice decoction, take at twice.
Therapeutic effect:
In People's Republic of China's Chinese medicine industry standard (ZY/T001-94):
Eight, in the TCM Dermatology disease Standardization of diagnosis and curative effect:
The diagnosis basis of 41 acne, syndrome-classification, efficacy evaluation.
Acne are mainly in face, sometimes can extrude the white a kind of dermatosis of sample powder juice as feature of cracking rice take pimple, pustule, tuberosity.Be equivalent to acne vulgaris.
41.1 diagnosis basis.
41.1.1 from the beginning of at follicular orifice, present the red pimple of small rice grain size, also can develop into pustule.After this can form scleroma sample hoary hair's acne or blackhead, serious case can form scleroma property cyst.
41.1.2 be mainly in face and the chest and back of men and women's adolescence, often with seborrhea.
41.1.3 eating and drinking without temperance is arranged more, surfeit delicious food savoury, or sense exopathogen etc. brings out.
41.1.4 after the adolescence, majority can alleviate naturally.
41.1.5 the women is many with menoxenia.
41.2 syndrome-classification.
41.2.1 wind and heat in the lung meridian: the pimple color is red, or the pain of itching is arranged.Red tongue, yellow and thin fur, floating and rapid pulse.
41.2.2 damp-heat accumulation: the erythra congestion and swelling pain, or pustule is arranged, halitosis, constipation, yellowish urine.Red tongue, yellow and greasy fur, slippery and rapid pulse.
41.2.3 phlegm-damp condenses: erythra is formed cyst, or have indigestion and loss of appetite, the loose stool.Light red tongue is fat, thin fur, rolling pulse.
41.3 efficacy evaluation.
41.3.1 cure: skin lesion is disappeared, subjective symptoms disappears.
41.3.2 take a turn for the better: subjective symptoms obviously alleviates, and skin lesion disappears more than 30%.
41.3.3 do not heal: skin lesion and symptom be the unchanged or less than 30% that disappears all.
According to the afore mentioned rules requirement, from 2010 01 month in December, 2012, patient diagnosis Acne treatment patient 120 people, age 13-28 year, wherein man: 78 people, woman: 42 people.Adopt the prescription of Chinese medicine composition of the present invention, one pair of every day, sooner or later be decocted in water for oral dose at twice 7 days courses for the treatment of.Through the treatment of 3 courses for the treatment of, cure 63 people, 48 people that take a turn for the better, 9 people of not healing.Cure rate 52.5%, total effective rate reaches 92.5%, and invalid 7.5%.
Among 120 people, lung meridian wind-heat type 40 people, damp-heat accumulation type 40 people, phlegm-damp condensation type 40 people all adopt Chinese medicine composition prescription of the present invention.The drug regimen prescription has been broken the syndrome boundary, has been taken into account the characteristics of incidence of each pattern of syndrome, has realized specific prescription for certain illness, and has obtained satisfied clinical efficacy.
Prescription of the present invention institute consumption is higher than the recommendation of the documents such as Chinese Pharmacopoeia, its reason, and the one,, the patient of acne is youngster mostly, reason causes and this disease is because savoury is rich etc.; The 2nd,, present Chinese herbal medicine is artificial culture mostly, its drug effect and genuine degree are all to some extent not as traditional wild Chinese herbal medicine.So the consumption of the more general patient of the consumption in the prescription and literature recommendation is large, this is also confirmed by practice.Large consumption in the employing side has been obtained good therapeutic effect.
In order to adapt to various different patients' needs, the Chinese medicine composition of this prescription can be made the dosage forms such as loose, ball, capsule or granule according to the regulation of Chinese Pharmacopoeia, conveniently to take and to apply.
Claims (3)
1. the Chinese medicine composition of an Acne treatment has Rhizoma Coptidis, Radix Scutellariae, the Radix Rehmanniae, Radix Angelicae Sinensis, Radix Sophorae Flavescentis, Radix Cynanchi Paniculati, Cortex Dictamni, Flos Lonicerae and Radix Glycyrrhizae, it is characterized in that each Chinese medicine material forms according to following mass fraction compatibility:
Rhizoma Coptidis 5-20 part, Radix Scutellariae 5-25 part, Radix Rehmanniae 10-30 part, Radix Angelicae Sinensis 8-30 part, Radix Sophorae Flavescentis 5-30 part, Radix Cynanchi Paniculati 5-30 part, Cortex Dictamni 5-25 part, Flos Lonicerae 10-30 part, Radix Glycyrrhizae 5-15 part.
2. according to the Chinese medicine composition of a kind of Acne treatment claimed in claim 1, it is characterized in that each Chinese medicine material of said Rhizoma Coptidis, Radix Scutellariae, the Radix Rehmanniae, Radix Angelicae Sinensis, Radix Sophorae Flavescentis, Radix Cynanchi Paniculati, Cortex Dictamni, Flos Lonicerae and Radix Glycyrrhizae forms according to following mass fraction compatibility:
Rhizoma Coptidis 10-15 part, Radix Scutellariae 10-20 part, Radix Rehmanniae 10-20 part, Radix Angelicae Sinensis 10-20 part, Radix Sophorae Flavescentis 10-20 part, Radix Cynanchi Paniculati 10-20 part, Cortex Dictamni 10-20 part, Flos Lonicerae 15-20 part, Radix Glycyrrhizae 8-15 part.
3. according to the Chinese medicine composition of a kind of Acne treatment claimed in claim 1, it is characterized in that each Chinese medicine material of said Rhizoma Coptidis, Radix Scutellariae, the Radix Rehmanniae, Radix Angelicae Sinensis, Radix Sophorae Flavescentis, Radix Cynanchi Paniculati, Cortex Dictamni, Flos Lonicerae and Radix Glycyrrhizae forms according to following mass fraction compatibility:
Rhizoma Coptidis 12-15 part, Radix Scutellariae 15-20 part, Radix Rehmanniae 15-20 part, Radix Angelicae Sinensis 15-20 part, Radix Sophorae Flavescentis 15-20 part, Radix Cynanchi Paniculati 15-20 part, Cortex Dictamni 15-20 part, Flos Lonicerae 15-20 part, Radix Glycyrrhizae 10-15 part.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104274749A (en) * | 2014-09-16 | 2015-01-14 | 田清峰 | Traditional Chinese medicinal composition for treating acne and preparation method thereof |
| CN104623442A (en) * | 2015-02-12 | 2015-05-20 | 严德华 | Medicine for treating acne |
| CN107362338A (en) * | 2017-07-06 | 2017-11-21 | 合肥丰瑞隆生物科技有限公司 | Anti-acne print ointment and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101569668A (en) * | 2008-12-18 | 2009-11-04 | 芮育健 | New application of Chinese herbal medicaments of radix geutianae, baikal skullcap root, forsythia fruit and coftis root for promoting blood circulation and dispelling wind and treating acne |
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| CN101569668A (en) * | 2008-12-18 | 2009-11-04 | 芮育健 | New application of Chinese herbal medicaments of radix geutianae, baikal skullcap root, forsythia fruit and coftis root for promoting blood circulation and dispelling wind and treating acne |
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| 李永久: "中医治疗痤疮临床验案", 《内蒙古中医药》, 15 April 2007 (2007-04-15), pages 22 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104274749A (en) * | 2014-09-16 | 2015-01-14 | 田清峰 | Traditional Chinese medicinal composition for treating acne and preparation method thereof |
| CN104623442A (en) * | 2015-02-12 | 2015-05-20 | 严德华 | Medicine for treating acne |
| CN104623442B (en) * | 2015-02-12 | 2018-06-26 | 严德华 | A kind of drug for treating whelk |
| CN107362338A (en) * | 2017-07-06 | 2017-11-21 | 合肥丰瑞隆生物科技有限公司 | Anti-acne print ointment and preparation method thereof |
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