CN102947438B - 用于细胞培养的装置和方法 - Google Patents

用于细胞培养的装置和方法 Download PDF

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Publication number
CN102947438B
CN102947438B CN201180023670.XA CN201180023670A CN102947438B CN 102947438 B CN102947438 B CN 102947438B CN 201180023670 A CN201180023670 A CN 201180023670A CN 102947438 B CN102947438 B CN 102947438B
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carrier
bioreactor
adjacent
bioreactors
area
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Chinese (zh)
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CN102947438A (zh
Inventor
迪迪耶·卡勒兰嘉博
朱利安·卡登
何塞·安东尼奥·卡斯蒂略冈萨雷斯
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Pouratris Private Ltd
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Artelis SA
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Priority claimed from GBGB1007863.2A external-priority patent/GB201007863D0/en
Priority claimed from GBGB1007861.6A external-priority patent/GB201007861D0/en
Priority claimed from GBGB1007855.8A external-priority patent/GB201007855D0/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
    • C12M3/04—Tissue, human, animal or plant cell, or virus culture apparatus with means providing thin layers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/06—Plates; Walls; Drawers; Multilayer plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/14—Apparatus for enzymology or microbiology with means providing thin layers or with multi-level trays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/04—Flat or tray type, drawers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/22—Transparent or translucent parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/44—Multiple separable units; Modules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN201180023670.XA 2010-05-11 2011-05-11 用于细胞培养的装置和方法 Active CN102947438B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB1007861.6 2010-05-11
GBGB1007863.2A GB201007863D0 (en) 2010-05-11 2010-05-11 Bioreactor for cell culture
GBGB1007861.6A GB201007861D0 (en) 2010-05-11 2010-05-11 Dynamic bioreactor for cell culture
GB1007863.2 2010-05-11
GBGB1007855.8A GB201007855D0 (en) 2010-05-11 2010-05-11 Bioreactor for the culture of cells
GB1007855.8 2010-05-11
PCT/EP2011/057621 WO2011141512A2 (en) 2010-05-11 2011-05-11 Apparatus and methods for cell culture

Publications (2)

Publication Number Publication Date
CN102947438A CN102947438A (zh) 2013-02-27
CN102947438B true CN102947438B (zh) 2017-01-18

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US (4) US9399755B2 (cg-RX-API-DMAC10.html)
EP (1) EP2516618B1 (cg-RX-API-DMAC10.html)
JP (2) JP5988962B2 (cg-RX-API-DMAC10.html)
KR (1) KR20130109000A (cg-RX-API-DMAC10.html)
CN (1) CN102947438B (cg-RX-API-DMAC10.html)
AU (1) AU2011252063A1 (cg-RX-API-DMAC10.html)
BR (1) BR112012028786A2 (cg-RX-API-DMAC10.html)
SG (2) SG10201503666UA (cg-RX-API-DMAC10.html)
WO (1) WO2011141512A2 (cg-RX-API-DMAC10.html)

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CN103146578B (zh) * 2013-03-29 2014-11-05 东北农业大学 转基因细胞培养装置
KR20150117599A (ko) * 2014-04-09 2015-10-20 에스케이이노베이션 주식회사 바이오매스의 연속당화 반응기
JP6840219B2 (ja) * 2016-03-14 2021-03-10 パテル ラビンドラカマー ディラブハイＰＡＴＥＬ，Ｒａｖｉｎｄｒａｋｕｍａｒ Ｄｈｉｒｕｂｈａｉ バイオリアクタシステム及びその方法
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JP6942448B2 (ja) * 2016-08-08 2021-09-29 株式会社カネカ 細胞培養容器、これを用いた細胞培養システム、および細胞培養方法
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KR102417445B1 (ko) * 2019-11-29 2022-07-06 주식회사 아모그린텍 세포배양장치
CA3168700A1 (en) 2020-01-20 2021-07-29 Adva Biotechnology Ltd. Device and method for controlling a bioreactor
CN113861296A (zh) * 2020-06-30 2021-12-31 广州凌腾生物医药有限公司 一种使用环轨摇晃式生物反应器制备双特异性抗体的方法
WO2022162722A1 (ja) * 2021-01-26 2022-08-04 株式会社日立ハイテク 無菌サンプリング装置および無菌サンプリング方法
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Also Published As

Publication number Publication date
US20170015967A1 (en) 2017-01-19
US20130059339A1 (en) 2013-03-07
SG185434A1 (en) 2012-12-28
US20220380711A1 (en) 2022-12-01
US20260152711A1 (en) 2026-06-04
JP2013526269A (ja) 2013-06-24
WO2011141512A2 (en) 2011-11-17
KR20130109000A (ko) 2013-10-07
EP2516618B1 (en) 2020-07-08
EP2516618A2 (en) 2012-10-31
JP5988962B2 (ja) 2016-09-07
WO2011141512A3 (en) 2012-03-15
BR112012028786A2 (pt) 2015-11-24
CN102947438A (zh) 2013-02-27
SG10201503666UA (en) 2015-06-29
JP2016144464A (ja) 2016-08-12
US9399755B2 (en) 2016-07-26
AU2011252063A1 (en) 2012-11-29

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