CN102906110B - 基于氯高铁血红素衍生物的抗微生物剂 - Google Patents

基于氯高铁血红素衍生物的抗微生物剂 Download PDF

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Publication number
CN102906110B
CN102906110B CN201080048604.3A CN201080048604A CN102906110B CN 102906110 B CN102906110 B CN 102906110B CN 201080048604 A CN201080048604 A CN 201080048604A CN 102906110 B CN102906110 B CN 102906110B
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arg
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Chinese (zh)
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CN102906110A (zh
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V·E·尼伯尔辛
G·A·哲尔塔基纳
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OBSCHESTVO S OGRANICHENNOI OTV
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OBSCHESTVO S OGRANICHENNOI OTV
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02—Iron compounds
    • C07F15/025—Iron compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201080048604.3A 2009-09-10 2010-09-08 基于氯高铁血红素衍生物的抗微生物剂 Expired - Fee Related CN102906110B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2009133914/04A RU2415868C1 (ru) 2009-09-10 2009-09-10 Производные гемина, обладающие антимикробной активностью, или их фармацевтически приемлемые соли, способ получения, фармкомпозиция и применение
RU2009133914 2009-09-10
PCT/RU2010/000488 WO2011031187A1 (ru) 2009-09-10 2010-09-08 Антимикробные средства на основе производных гемина

Publications (2)

Publication Number Publication Date
CN102906110A CN102906110A (zh) 2013-01-30
CN102906110B true CN102906110B (zh) 2016-04-13

Family

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CN201080048604.3A Expired - Fee Related CN102906110B (zh) 2009-09-10 2010-09-08 基于氯高铁血红素衍生物的抗微生物剂

Country Status (11)

Country Link
US (1) US8906897B2 (enExample)
EP (1) EP2476701B8 (enExample)
CN (1) CN102906110B (enExample)
DK (1) DK2476701T3 (enExample)
EA (1) EA020802B1 (enExample)
ES (1) ES2527432T3 (enExample)
IN (1) IN2012DN02980A (enExample)
PL (1) PL2476701T3 (enExample)
RU (1) RU2415868C1 (enExample)
UA (1) UA108480C2 (enExample)
WO (1) WO2011031187A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2475498C1 (ru) * 2011-11-17 2013-02-20 Общество С Ограниченной Ответственностью "Фарминтерпрайсез" Новые производные гемина с антибактериальной и противовирусной активностью
CN102967649B (zh) * 2012-05-24 2015-03-04 新疆科丽生物技术有限公司 电感耦合等离子体质谱在氯高铁血红素药物检测中的应用
ES2864829T3 (es) * 2016-09-15 2021-10-14 Nano4Imaging Gmbh Conjugados de tetrapirrol como agentes de contraste IRM
RU2678985C2 (ru) 2017-02-06 2019-02-05 Общество с ограниченной ответственностью "Научно-производственная фирма ВЕРТА" Биоцидный пептид и препарат на его основе
US12064514B2 (en) * 2017-07-28 2024-08-20 The Penn State Research Foundation Ultrasound-sensitive peptide particles for spatially resolved molecule delivery
RU2656595C1 (ru) * 2018-03-16 2018-06-06 Общество С Ограниченной Ответственностью "Фарминтерпрайсез" Циклическое производное гемина с антимикробными свойствами и способ его синтеза

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2193038C2 (ru) * 1995-11-24 2002-11-20 Йеда Рисерч Энд Дивелопмент Ко., Лтд. Способ получения металлсодержащих производных бактериохлорофилла, новые металлированные производные бактериохлорофилла, фармацевтическая композиция
RU2238950C2 (ru) * 2002-04-25 2004-10-27 Небольсин Владимир Евгеньевич Производные гемина и их фармацевтически приемлемые соли, способ получения, применение и фармацевтическая композиция
RU2007125604A (ru) * 2007-07-09 2009-01-20 ООО "Фарминтерпрайсез" (RU) Производные гемина или их фармацевтически приемлемые соли, способ получения, композиция и применение

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2113837A1 (en) * 1991-08-02 1993-02-18 Kenji Mizumoto Anti-hiv agent
US6001808A (en) 1996-08-19 1999-12-14 Metatron, Inc. Method of treating herpes virus infections with spermostatic gramicidin
RU2250906C2 (ru) * 2003-07-10 2005-04-27 Небольсин Владимир Евгеньевич Способы получения геминпептидов и их применение в качестве нуклеолитических агентов
RU2280649C1 (ru) 2004-11-26 2006-07-27 ООО "Фарминтерпрайсез" Геминпептиды, их фармацевтически приемлемые соли, фармкомпозиция и применение в качестве противоопухолевых агентов
RU2296131C2 (ru) * 2004-11-26 2007-03-27 ООО "Фарминтерпрайсез" Геминпептид, его фармацевтически приемлемые соли и применение в качестве противовирусного и вирулецидного агента

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2193038C2 (ru) * 1995-11-24 2002-11-20 Йеда Рисерч Энд Дивелопмент Ко., Лтд. Способ получения металлсодержащих производных бактериохлорофилла, новые металлированные производные бактериохлорофилла, фармацевтическая композиция
RU2238950C2 (ru) * 2002-04-25 2004-10-27 Небольсин Владимир Евгеньевич Производные гемина и их фармацевтически приемлемые соли, способ получения, применение и фармацевтическая композиция
RU2007125604A (ru) * 2007-07-09 2009-01-20 ООО "Фарминтерпрайсез" (RU) Производные гемина или их фармацевтически приемлемые соли, способ получения, композиция и применение

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Hemin potentiates the anti-hepatitis C virus activity of the antimalarial drug artemisinin;Jan Paeshuyse et al.;《Biochemical and Biophysical Research Communications》;20060915;第348卷(第1期);第139-144页 *
氯高铁血红素的抗贫血作用;林建峰等;《中国生化药物杂志》;19970215;第18卷(第1期);第34-36页 *

Also Published As

Publication number Publication date
IN2012DN02980A (enExample) 2015-07-31
RU2415868C1 (ru) 2011-04-10
DK2476701T3 (en) 2014-11-17
EP2476701B1 (en) 2014-08-13
WO2011031187A1 (ru) 2011-03-17
HK1179278A1 (zh) 2013-09-27
ES2527432T3 (es) 2015-01-23
US20120264724A1 (en) 2012-10-18
EA201270405A1 (ru) 2012-08-30
EP2476701B8 (en) 2014-09-24
PL2476701T3 (pl) 2015-03-31
UA108480C2 (en) 2015-05-12
EP2476701A1 (en) 2012-07-18
US8906897B2 (en) 2014-12-09
CN102906110A (zh) 2013-01-30
EP2476701A4 (en) 2013-01-16
EA020802B1 (ru) 2015-01-30

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