CN102885879A - Method for producing yupingfeng lyophilized powder capsule - Google Patents
Method for producing yupingfeng lyophilized powder capsule Download PDFInfo
- Publication number
- CN102885879A CN102885879A CN2012104395097A CN201210439509A CN102885879A CN 102885879 A CN102885879 A CN 102885879A CN 2012104395097 A CN2012104395097 A CN 2012104395097A CN 201210439509 A CN201210439509 A CN 201210439509A CN 102885879 A CN102885879 A CN 102885879A
- Authority
- CN
- China
- Prior art keywords
- yupingfeng
- powder capsule
- producing
- lyophilized powder
- frozen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicinal Preparation (AREA)
Abstract
The invention discloses a method for producing a yupingfeng lyophilized powder capsule. The method for producing the capsule comprises the following steps: extracting astragalus, divaricate saposhnikovia root and largehead atractylodes rhizome under a certain condition; granulating extracts and then producing the lyophilized powder capsule the quality of which meets the requirements. The yupingfeng lyophilized powder capsule which is produced through the method meets the requirements of identification, content and the like, so that the product quality is effectively guaranteed.
Description
Technical field
The present invention relates to the preparation method of plant pharmaceutical formulation, particularly relate to the preparation method of Yupingfeng freeze-dried powder capsule.
Background technology
Yupingfeng has good QI invigorating as a kind of Chinese patent medicine, consolidating superficial resistance, anti-hidropoiesis.Existing multiple dosage form on the market is such as pill, powder, granule, oral liquid etc.
The invention provides a kind of preparation method of new Yupingfeng freeze-dried powder capsule.
Goal of the invention
The invention provides a kind of new Yupingfeng dosage form, to guarantee that its moisture is controlled.
Summary of the invention
The invention provides a kind of preparation method of new Yupingfeng freeze-dried powder capsule.
The preparation method of Yupingfeng freeze-dried powder capsule is:
1. the Radix Astragali Radix Saposhnikoviae Rhizoma Atractylodis Macrocephalae (stir-fry)
1.1 above three flavors, Radix Saposhnikoviae is cut off, and extracts volatile oil, and the aqueous solution after the distillation in addition device is collected; Medicinal residues and all the other Radixs Astragali two flavors decoct with water secondary, and 1.5 hours for the first time, 1 hour for the second time, the aqueous solution that collecting decoction and other device are collected filters, and filtrate is concentrated in right amount, add isopyknic ethanol, stir, leave standstill, get supernatant, decompression recycling ethanol is concentrated into the clear paste that relative density is about 1.08 (80 ℃), spray drying gets fine powder, add Radix Saposhnikoviae volatile oil, airtight 2 hours, granulate.
Adopt following method to prepare the Yupingfeng freeze-dried powder capsule, 1 part of YUPINGFENG KELI is mixed with frozen-dried supporting agent 0.6-3.2 part with the water for injection dissolving again, filters, the fine straining degerming, packing, lyophilizing, incapsulate, preferred drug ratio is 1 part of YUPINGFENG KELI, 1.4 parts of frozen-dried supporting agents.Frozen-dried supporting agent can be mannitol, glucose, sucrose or lactose, preferred mannitol.
Further set forth the present invention below by example, but do not place restrictions on the present invention.
The specific embodiment
Embodiment one:
1, the Radix Astragali 300g Radix Saposhnikoviae 100g Rhizoma Atractylodis Macrocephalae (stir-fry) 100g
1.1, above three flavors, Radix Saposhnikoviae is cut off, and extracts volatile oil, the aqueous solution after the distillation in addition device is collected; Medicinal residues and all the other Radixs Astragali two flavors decoct with water secondary, and 1.5 hours for the first time, 1 hour for the second time, the aqueous solution that collecting decoction and other device are collected filters, and filtrate is concentrated in right amount, add isopyknic ethanol, stir, leave standstill, get supernatant, decompression recycling ethanol is concentrated into the clear paste that relative density is about 1.08 (80 ℃), spray drying gets fine powder, add Radix Saposhnikoviae volatile oil, airtight 2 hours, granulate.
Adopt following method to prepare the Yupingfeng freeze-dried powder capsule, YUPINGFENG KELI 50g, for subsequent use with 1/2 amount water for injection dissolving.Other gets mannitol 70g and is dissolved in an amount of water for injection, mixes with YUPINGFENG KELI solution, adds water for injection to 5000ml.Filter cold preservation 8 hours.Cold preservation liquid 0.2um microporous filter membrane fine straining, lyophilizing incapsulates, average every loading amount 0.5g, totally 1000.Finished product detection, packing.
Claims (3)
1. the preparation method of a Yupingfeng freeze-dried powder capsule, the Radix Astragali, Radix Saposhnikoviae, Rhizoma Atractylodis Macrocephalae extract granulation be is characterized in that 1 part of the granule that the Radix Astragali, Radix Saposhnikoviae, Rhizoma Atractylodis Macrocephalae extract make, mix with frozen-dried supporting agent 0.5-3 part again with the water for injection dissolving, filter, the fine straining degerming, packing, lyophilizing, incapsulate packing.
2. according to claims 1 described preparation method, it is characterized in that preferred drug ratio is the granule (containing the Radix Astragali with astragaloside 0.4mg in every) that the Radix Astragali, Radix Saposhnikoviae, Rhizoma Atractylodis Macrocephalae extract are made, 1.4 parts of frozen-dried supporting agents.
3. according to claims 1 described preparation method, it is characterized in that selected frozen-dried supporting agent can be mannitol, glucose, sucrose or lactose, preferred mannitol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012104395097A CN102885879A (en) | 2012-11-02 | 2012-11-02 | Method for producing yupingfeng lyophilized powder capsule |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012104395097A CN102885879A (en) | 2012-11-02 | 2012-11-02 | Method for producing yupingfeng lyophilized powder capsule |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102885879A true CN102885879A (en) | 2013-01-23 |
Family
ID=47529697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012104395097A Pending CN102885879A (en) | 2012-11-02 | 2012-11-02 | Method for producing yupingfeng lyophilized powder capsule |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102885879A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1475242A (en) * | 2002-08-16 | 2004-02-18 | 成都市药友科技发展有限公司 | Preparation method of ginkgo leaf extract freeze dried powder injection |
| CN101411743A (en) * | 2007-11-16 | 2009-04-22 | 安徽医科大学 | Use of Chinese medicine jade screen powder as medicament for preventing and treating liver damage |
| CN101584748A (en) * | 2009-06-22 | 2009-11-25 | 大连工业大学 | Method for preparing shizandra active freeze-dried powder and capsules |
| CN101773541A (en) * | 2009-12-22 | 2010-07-14 | 上海悦胜芜湖药业有限公司 | Yupingfeng soft capsule |
-
2012
- 2012-11-02 CN CN2012104395097A patent/CN102885879A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1475242A (en) * | 2002-08-16 | 2004-02-18 | 成都市药友科技发展有限公司 | Preparation method of ginkgo leaf extract freeze dried powder injection |
| CN101411743A (en) * | 2007-11-16 | 2009-04-22 | 安徽医科大学 | Use of Chinese medicine jade screen powder as medicament for preventing and treating liver damage |
| CN101584748A (en) * | 2009-06-22 | 2009-11-25 | 大连工业大学 | Method for preparing shizandra active freeze-dried powder and capsules |
| CN101773541A (en) * | 2009-12-22 | 2010-07-14 | 上海悦胜芜湖药业有限公司 | Yupingfeng soft capsule |
Non-Patent Citations (1)
| Title |
|---|
| 方修贵等: "刺梨的营养价值及其开发利用", 《食品工业科技》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103393599B (en) | Preparation method of traditional Chinese medicine fine powder | |
| CN101229236A (en) | Relieve asthma oral liquid preparation and preparing method thereof | |
| CN101284120A (en) | Process for preparing Pingxiao preparation | |
| EP1972337A2 (en) | Excipient and an improved method for manufacturing extracted, evaporated, granulated botanical herb product | |
| CN101966244A (en) | Preparation method of sugar-free type anti-cold and antidotal granule | |
| CN105079466A (en) | Jinxianlian effervescent tablet and preparation method thereof | |
| CN107617036A (en) | A kind of Liuwei Dihuang Wan and its preparation technology | |
| CN103566165A (en) | Process of exocarpium citri grandis tablets | |
| CN103784771A (en) | Traditional Chinese medicine composition has functions of anticoccidia, haemostasis and blood enriching, and antibiosis and antiphlogosis, and preparation method thereof | |
| CN1171624C (en) | Method for preparing Chinese medicine Liuwei Dihuang preparation | |
| CN103933295A (en) | Six-ingredient rehmannia pill and preparation technology thereof | |
| CN104666629A (en) | Preparation method of Zhongganling capsules and quality detection method of Zhongganling capsules | |
| CN101199669A (en) | Chinese medicine compound agent for treating female sperm quality lowclass | |
| CN100411657C (en) | Green biota body cleaning effervescent particle preparation | |
| CN102885879A (en) | Method for producing yupingfeng lyophilized powder capsule | |
| CN106138772A (en) | Gastrodia tuber and fleece-flower root combined pharmaceutical composition and preparation technology thereof | |
| CN106109968A (en) | Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata pharmaceutical composition and preparation method thereof | |
| CN102940724A (en) | Preparation method of traditional Chinese medicine compound capsule for diminishing inflammation | |
| CN100998776B (en) | Traditional Chinese medicine effervescent tablets for inducing sweat, cleaning damp and harmonizing middle-jiao, and its preparing method | |
| CN106389798A (en) | Extraction method for ziziphus jujuba mill.var.spinosa decoction prescription and tuckahoe-cassia twig-atractylodes macrocephala koidz-licorice root decoction prescription | |
| CN104998225A (en) | Medicinal preparation for treatment of constipation | |
| CN100998787A (en) | Traditional Chinese medicine effervescent tablets for treating gastrointestinal disease and its preparing method | |
| CN112515026A (en) | Ginseng small-molecule peptide tablet candy and purification preparation process | |
| CN106075104A (en) | Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata combined pharmaceutical composition and preparation method thereof | |
| CN103566318A (en) | Preparation method of Huoxiangzhengqi capsule |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20130123 |