CN102879596A - Sample charging method and device applied to full-automatic hematology analyzer - Google Patents
Sample charging method and device applied to full-automatic hematology analyzer Download PDFInfo
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- CN102879596A CN102879596A CN2012103907774A CN201210390777A CN102879596A CN 102879596 A CN102879596 A CN 102879596A CN 2012103907774 A CN2012103907774 A CN 2012103907774A CN 201210390777 A CN201210390777 A CN 201210390777A CN 102879596 A CN102879596 A CN 102879596A
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Abstract
The invention discloses a sample charging method and a sample charging device applied to a full-automatic hematology analyzer, and belongs to blood detection equipment, in particular to a sampling charging method and a sampling charging device applied to a full-automatic hematology analyzer for blood routine examination. The device comprises a measuring cup for containing a dilute whole blood sample and a sampling needle which can run to each measuring cup and contains a whole blood sample, and is characterized in that the upper end of the measuring cup is cylindrical, and the lower end of the measuring cup is tapered; a diluent pipeline forming an included angle of 5 to 30 degrees with the horizontal plane is arranged in the tangential direction of the sidewall of the middle part of the measuring cup; an outlet of the pipeline is opposite to the sampling needle; and the lower port of the sampling needle is 1 to 5mm lower than the outlet of the diluent pipeline. By the method, a whole flood sample droplet formed at the lower end of the sampling needle can be washed, and a diluent flowing out of a traction pipeline at constant speed spirally flows downwards along the inner wall of the measuring cup, and simultaneously drives the flow of the whole blood sample, so that the diluent and the whole blood sample can be uniformly mixed, and the morphology and size of each blood cell can be well maintained.
Description
Technical field
The invention belongs to blood testing equipment, method and the device of the sample filling of the Automatic Blood Cell Analyzer that particularly uses in the clinical examination routine blood test project.
Background technology
The leucocyte five classification Automatic Blood Cell Analyzers that use in the clinical examination routine blood test project require trace blood, approximately need to use 60 microlitre whole blood samples to measure, and whole blood sample need to be filled into respectively different measuring cups, the whole blood sample of filling only is tens microlitres in each measuring cup, when sampling probe puts in the inside filling whole blood sample of measuring cup, the whole blood sample of sampling probe inside lower end at sampling probe under syringe pump promotes forms a droplet, there is dilution to flow out in the sampling probe outer wall washing spare, along the sampling probe outer wall to dirty, the whole blood sample that hangs over the sampling probe lower end is filled in the measuring cup, after the sample filling is complete, the dilution of sampling probe outer wall also adds continuing according to dilution ratio, although this moment, syringe pump stopped, but, downward swiftly flowing dilution forms negative pressure at the lower port place of sampling probe, the inner remaining whole blood sample of sampling probe can be sucked away a part, along with dilution together is filled in the measuring cup, cause the whole blood sample adding amount inaccurate, the whole blood sample and the dilution that are filled into measuring cup inside also need to carry out the mixing operation, normally enter air stream in the bottom of measuring cup, air stream forms a lot of bubbles and the rapid movement that makes progress in the mixed liquor of whole blood sample and dilution, reach the effect with whole blood sample and dilution mixing, but form quantity and direction of motion and the very difficult accurately control of speed of bubble, will affect the form of various haemocytes in the whole blood sample and volume if bubble breaks.
Summary of the invention
Also need the mixing processing ease to form bubble, can affect the form of various haemocytes in the whole blood sample and the deficiency of volume after not accurate enough, the filling of metering when overcoming existing leucocyte five classification Automatic Blood Cell Analyzers filling whole blood sample, the purpose of this invention is to provide a kind of device that is applicable to the sample filling of Automatic Blood Cell Analyzer, another object of the present invention provides a kind of method that is applicable to the sample filling of Automatic Blood Cell Analyzer of using this device.
Technical scheme of the present invention is, a kind of device that is applicable to the sample filling of Automatic Blood Cell Analyzer, comprise the whole blood sample of splendid attire dilution measuring cup, can run to the sampling probe of the splendid attire whole blood sample of each measuring cup, it is characterized in that: be that cylindric lower end be that the sidewall tangential direction at the measuring cup middle part of taper is installed with horizontal plane angle is the dilution pipeline of 5-30 degree in the upper end, the outlet forward of dilution pipeline is facing to sampling probe, and the sampling probe lower port is lower than the outlet 1-5mm of dilution pipeline.
Use the method for sample filling of the device of aforesaid a kind of sample filling that is applicable to Automatic Blood Cell Analyzer, it is characterized in that: sampling probe runs to the inside of measuring cup, the lower port of sampling probe 1 is lower than diluted liquid tube way outlet 1-5mm, the external unit syringe pump that is connected with sampling probe 1 promotes the whole blood sample in the sampling probe downwards, and at drop of sampling probe lower end formation, dilution is flowed out by the outlet of dilution pipeline, and flow downward in a spiral manner along the inwall of measuring cup, whole blood sample drop to the sampling probe lower end washes, flowing of the whole blood sample of simultaneously drive injection measuring cup, the whole blood sample of dilution and filling is evenly mixed in measuring cup, form the whole blood sample of dilution, whole blood sample in first measuring cup, annotate complete after, sampling probe will move to next measuring cup remaining whole blood sample will be annotated, operation steps repeats said process, until all measuring cups all annotate complete after, shut-down operation.
The invention provides a kind of use simple in structure is installed in and sweeps the stream pipeline on the measuring cup sidewall, can wash at short notice the whole blood sample droplet that the sampling probe lower end forms by sweeping the dilution that flows out in the stream pipeline, wash complete rear sampling probe and move to another measuring cup continuation filling.Sweeping the dilution that at the uniform velocity flows out of stream pipeline flows downward in a spiral manner along the inwall of measuring cup, drive simultaneously flowing of whole blood sample, can realize preferably the even mixing of dilution and whole blood sample, and no longer need independent mixing to operate, the volume ratio of dilution and whole blood sample is very large in this operation, whole blood sample flows in a large amount of dilutions, can keep preferably form and the volume of each haemocyte.
The invention has the beneficial effects as follows the many deficiencies that overcome background technology, have that device structure is simple, high reliability.
Description of drawings
Fig. 1 is structural representation of the present invention,
Fig. 2 is that the A-A of Fig. 1 is to cut-open view.
Among the figure, 1. sampling probe, 2. whole blood sample, 3. measuring cup, 4. dilution pipeline, the 5. whole blood sample of dilution, 6. diluent flow direction signal.
Embodiment
The specific embodiment of the present invention is, as shown in the figure:
Claims (2)
1. the device of a sample filling that is applicable to Automatic Blood Cell Analyzer, comprise the whole blood sample of splendid attire dilution measuring cup, can run to the sampling probe of the splendid attire whole blood sample of each measuring cup, it is characterized in that: be that cylindric lower end be that the sidewall tangential direction at the measuring cup middle part of taper is installed with horizontal plane angle is the dilution pipeline of 5-30 degree in the upper end, the outlet forward of dilution pipeline is facing to sampling probe, and the sampling probe lower port is lower than the outlet 1-5mm of dilution pipeline.
2. right to use requires the method for sample filling of the device of 1 described a kind of sample filling that is applicable to Automatic Blood Cell Analyzer, it is characterized in that: sampling probe runs to the inside of measuring cup, the lower port of sampling probe 1 is lower than diluted liquid tube way outlet 1-5mm, the external unit syringe pump that is connected with sampling probe 1 promotes the whole blood sample in the sampling probe downwards, and at drop of sampling probe lower end formation, dilution is flowed out by the outlet of dilution pipeline, and flow downward in a spiral manner along the inwall of measuring cup, whole blood sample drop to the sampling probe lower end washes, flowing of the whole blood sample of simultaneously drive injection measuring cup, the whole blood sample of dilution and filling is evenly mixed in measuring cup, form the whole blood sample of dilution, whole blood sample in first measuring cup, annotate complete after, sampling probe will move to next measuring cup remaining whole blood sample will be annotated, operation steps repeats said process, until all measuring cups all annotate complete after, shut-down operation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012103907774A CN102879596A (en) | 2012-10-15 | 2012-10-15 | Sample charging method and device applied to full-automatic hematology analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012103907774A CN102879596A (en) | 2012-10-15 | 2012-10-15 | Sample charging method and device applied to full-automatic hematology analyzer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102879596A true CN102879596A (en) | 2013-01-16 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN2012103907774A Pending CN102879596A (en) | 2012-10-15 | 2012-10-15 | Sample charging method and device applied to full-automatic hematology analyzer |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107121563A (en) * | 2017-04-09 | 2017-09-01 | 嘉兴新博信息科技有限公司 | Sample filling apparatus is used in a kind of medical treatment detection |
| CN113188865A (en) * | 2021-04-29 | 2021-07-30 | 河南科技大学第一附属医院 | Before processing apparatus is used in excrement and urine sample test for intensive care unit |
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| JPS5518976A (en) * | 1978-07-28 | 1980-02-09 | Toshiba Corp | Dispenser |
| CN1225454A (en) * | 1997-10-28 | 1999-08-11 | Abx公司 | Method and device for fractionted distribution of blood sample |
| CN1900716A (en) * | 2002-11-18 | 2007-01-24 | 希森美康株式会社 | Sample analyzer and its components |
| CN101074949A (en) * | 2006-05-17 | 2007-11-21 | 深圳迈瑞生物医疗电子股份有限公司 | Apparatus and method for dispensing and washing sampler |
| US20100158755A1 (en) * | 2003-09-19 | 2010-06-24 | Kabushiki Kaisha Toshiba | Chemical analyzer, method for dispensing and dilution cup |
| CN201607358U (en) * | 2009-12-11 | 2010-10-13 | 上海快德行生物技术有限公司 | Mixing device of medical testing sample |
| CN102305871A (en) * | 2011-08-24 | 2012-01-04 | 山东兰桥医学科技有限公司 | Multichannel blood distributing device and multichannel blood distributing method |
| CN202794203U (en) * | 2012-10-15 | 2013-03-13 | 济南美医林电子仪器有限公司 | Device suitable for sample filling of full-automatic blood cell analyzer |
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2012
- 2012-10-15 CN CN2012103907774A patent/CN102879596A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5518976A (en) * | 1978-07-28 | 1980-02-09 | Toshiba Corp | Dispenser |
| CN1225454A (en) * | 1997-10-28 | 1999-08-11 | Abx公司 | Method and device for fractionted distribution of blood sample |
| CN1900716A (en) * | 2002-11-18 | 2007-01-24 | 希森美康株式会社 | Sample analyzer and its components |
| US20100158755A1 (en) * | 2003-09-19 | 2010-06-24 | Kabushiki Kaisha Toshiba | Chemical analyzer, method for dispensing and dilution cup |
| CN101074949A (en) * | 2006-05-17 | 2007-11-21 | 深圳迈瑞生物医疗电子股份有限公司 | Apparatus and method for dispensing and washing sampler |
| CN201607358U (en) * | 2009-12-11 | 2010-10-13 | 上海快德行生物技术有限公司 | Mixing device of medical testing sample |
| CN102305871A (en) * | 2011-08-24 | 2012-01-04 | 山东兰桥医学科技有限公司 | Multichannel blood distributing device and multichannel blood distributing method |
| CN202794203U (en) * | 2012-10-15 | 2013-03-13 | 济南美医林电子仪器有限公司 | Device suitable for sample filling of full-automatic blood cell analyzer |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107121563A (en) * | 2017-04-09 | 2017-09-01 | 嘉兴新博信息科技有限公司 | Sample filling apparatus is used in a kind of medical treatment detection |
| CN107121563B (en) * | 2017-04-09 | 2018-06-29 | 知几未来（成都）临床医学检验有限公司 | A kind of medical treatment detection sample filling apparatus |
| CN113188865A (en) * | 2021-04-29 | 2021-07-30 | 河南科技大学第一附属医院 | Before processing apparatus is used in excrement and urine sample test for intensive care unit |
| CN113188865B (en) * | 2021-04-29 | 2022-11-04 | 河南科技大学第一附属医院 | Before processing apparatus is used in excrement and urine sample test for intensive care unit |
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Application publication date: 20130116 |