CN103861850B - A kind of cleaning device of specimen needle and method - Google Patents
A kind of cleaning device of specimen needle and method Download PDFInfo
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- CN103861850B CN103861850B CN201410080154.6A CN201410080154A CN103861850B CN 103861850 B CN103861850 B CN 103861850B CN 201410080154 A CN201410080154 A CN 201410080154A CN 103861850 B CN103861850 B CN 103861850B
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- specimen needle
- liquid
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- pipeline
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B9/00—Cleaning hollow articles by methods or apparatus specially adapted thereto
- B08B9/02—Cleaning pipes or tubes or systems of pipes or tubes
- B08B9/027—Cleaning the internal surfaces; Removal of blockages
- B08B9/032—Cleaning the internal surfaces; Removal of blockages by the mechanical action of a moving fluid, e.g. by flushing
Abstract
<b> the present invention relates to medical field, is specifically related to a kind of cleaning device and method of specimen needle.The cleaning device of this specimen needle uses two liquid driving devices to carry out beating liquid to sample pin, realize the forward to specimen needle and back flush, further raising flush efficiency and developing result, when ensureing developing result, which is shorter than the single flushing time used, not only can rinse specimen needle and sample preparation pipeline simultaneously, also can rinse specimen needle and sample preparation pipeline respectively.The cleaning method of this specimen needle rinses sample and prepares pipeline while backwash specimen needle, and this washing time is set to preset time value </b><bGreatT.Gre aT.GTT1</b><bGre atT.GreaT.GT, when forward flushing is carried out to specimen needle, this washing time is set to preset time value </b><bGreatT.Gre aT.GTT2</b><bGre atT.GreaT.GT, and to hocket according to </b><bGreatT.Gre aT.GTT1/T2</b><b > or </b><bGreatT.Gre aT.GTT2/T1</b><b > hockets, further improve flush efficiency and the developing result of specimen needle and sample preparation pipeline.</b>
Description
Technical field
the present invention relates to medical field, be specifically related to a kind of cleaning device and method of specimen needle.
Background technology
in flow cytometer, specimen needle is the flow channel of sample stream, and sample to be tested penetrates from specimen needle and under the parcel of sheath stream, forms narrow and stable sample areas and enters flow chamber under the promotion of liquid malleation.Sample to be tested particle flows through flow chamber with arrangement mode, irradiate the particle in sample stream by laser and collect the various types of scattered light signals produced in irradiation, in conjunction with biological property, statistic of classification is carried out to signal, obtain the parameter information with clinical meaning.
the latus rectum of specimen needle is very little, be generally 0.1-0.4mm, and the liquid flow through in specimen needle is generally the mixed reactant of blood and reagent, owing to containing protein and various clotting factor in blood, the inwall being easily attached to specimen needle forms the accumulations such as blood dirt, blocking specimen needle.In measuring process, also likely can bring other various impurity simultaneously, the skin histology that such as, puncture in blood collection procedure brings, all kinds of impurity contained in the puncture chip that brings of test tube and reagent, these impurity also may form blocking along with sample flow to into specimen needle.Once specimen needle generation stopping state can cause sample stream to occur extremely, measuring-signal distortion, produce the clinical diagnosis information of mistake, more seriously fluid path pipeline pressurized is excessive collapses pipe.
at present, for the cleaning of specimen needle, simultaneously major way rinses sample by single syringe to prepare pipeline and the realization of recoil specimen needle, the cleaning way of this routine has several restriction: when syringe rinses sample preparation pipeline and specimen needle simultaneously, because the latus rectum of specimen needle is little, liquid resistance prepares pipeline much larger than sample, and the fluid flow therefore flowing through specimen needle is little; When syringe rinses sample preparation pipeline and specimen needle simultaneously, the liquid velocity flowing through specimen needle is low.
Summary of the invention
for overcoming above-mentioned defect, namely object of the present invention is the cleaning device providing a kind of specimen needle, this device can rinse specimen needle simultaneously and sample prepares pipeline, also can rinse specimen needle and sample preparation pipeline respectively, and improve flush efficiency and developing result further.
the present invention also aims to the cleaning method providing a kind of specimen needle, the method can prepare pipeline to specimen needle and sample and rinse simultaneously, and can obtain higher flush efficiency and good developing result.
the object of the invention is to be achieved through the following technical solutions:
the cleaning device of a kind of specimen needle of the present invention, comprising: specimen needle, specimen needle fixed chamber specimen needle be fixed, built with the liquid storage tank of cleaning fluid, and first liquid drive unit, second liquid drive unit;
the outlet docking specimen needle fixed chamber entrance of described specimen needle, the entrance of described specimen needle is connected with the first sample and prepares pipeline and the second sample preparation pipeline; Described first liquid drive unit is connected with first passage conversion and on-off controller, and described first passage conversion is connected liquid storage tank with one end of on-off controller, and the other end connects the outlet of specimen needle fixed chamber; Described second liquid drive unit is connected with second channel conversion and on-off controller, and described second channel conversion is connected liquid storage tank with one end of on-off controller, and the other end connects the first sample and prepares pipeline;
described cleaning device also comprises liquid container group, described liquid container group prepares pipeline with described second sample and specimen needle fixed chamber entrance is connected, the break-make of pipeline and specimen needle fixed chamber entrance is prepared for controlling described second sample, the cleaning fluid second sample being prepared to pipeline and the conveying of specimen needle fixed chamber entrance stores, and the cleaning fluid loopback stored is prepared pipeline and specimen needle fixed chamber entrance to the second sample.
further, described liquid container group comprises first liquid container, second liquid container, first passage on-off controller, second channel on-off controller; Described first liquid container connects first passage on-off controller, specimen needle fixed chamber entrance successively, and described second liquid container connects second channel on-off controller successively, the second sample prepares pipeline.
further, described liquid container group comprises liquid container, and the third channel be connected with this liquid container is changed and on-off controller; It is described that third channel conversion is connected specimen needle fixed chamber entrance respectively with the two ends of on-off controller, the second sample prepares pipeline.
further, described specimen needle fixed chamber is flow chamber.
further, the other end of the conversion of described first passage and on-off controller to be exported with specimen needle fixed chamber by third channel on-off controller and is connected, and passes through four-way on-off controller and to change with second channel and the other end of on-off controller is connected.
apply a method for the cleaning device of above-mentioned a kind of specimen needle, comprise the following steps:
after first liquid drive unit draws cleaning fluid from liquid storage tank, first passage conversion and on-off controller carry out passage bridge, cleaning fluid enters specimen needle by the outlet of specimen needle fixed chamber under the driving of first liquid drive unit, flow through the second sample preparation pipeline from specimen needle entrance subsequently and enter liquid container group, back flush is carried out to specimen needle; While back flush is carried out to specimen needle, second liquid drive unit draws cleaning fluid from liquid storage tank, second channel conversion and on-off controller carry out passage bridge, cleaning fluid flows through the first sample preparation pipeline under the driving of second liquid drive unit, the second sample prepares pipeline and enters liquid container group, prepares pipeline rinse specimen needle and first and second sample;
after second liquid drive unit draws cleaning fluid from liquid storage tank, second channel conversion and on-off controller carry out passage bridge, cleaning fluid flows through the first sample preparation pipeline under the driving of second liquid drive unit, specimen needle entrance enters specimen needle, flow through specimen needle outlet subsequently, specimen needle fixed chamber entrance enters liquid container group, carries out forward flushing to specimen needle;
the time of described specimen needle back flush is preset time value T1, and the time that described specimen needle forward rinses is preset time value T2; Described cleaning method hockets according to T1/T2 or T2/T1 hockets.
further, described cleaning fluid is diluent or cleaning agent.
the cleaning device of a kind of specimen needle provided by the invention and method, the cleaning device of this specimen needle uses two liquid driving devices to carry out beating liquid to sample pin, realize the forward to specimen needle and back flush, further raising flush efficiency and developing result, when ensureing developing result, which is shorter than the single flushing time used, not only can rinse specimen needle and sample preparation pipeline simultaneously, also can rinse specimen needle and sample preparation pipeline respectively.The cleaning method of this specimen needle rinses sample and prepares pipeline while backwash specimen needle, and this washing time is set to preset time value T1, when forward flushing is carried out to specimen needle, this washing time is set to preset time value T2, and to hocket according to T1/T2 or T2/T1 hockets, further improve flush efficiency and developing result that specimen needle and sample prepare pipeline.
Accompanying drawing explanation
for ease of illustrating, the present invention is described in detail by following preferred embodiment and accompanying drawing.
fig. 1 is cleaning device and method embodiment schematic diagram of a kind of specimen needle of the present invention;
fig. 2 is cleaning device and another embodiment schematic diagram of method of a kind of specimen needle of the present invention.
Detailed description of the invention
in order to make object of the present invention, technical scheme and advantage clearly understand, below in conjunction with drawings and Examples, the present invention is further elaborated.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.
refer to Fig. 1, the cleaning device of a kind of specimen needle of the present invention, comprising: specimen needle 11, specimen needle fixed chamber specimen needle 11 be fixed, built with the liquid storage tank 1 of cleaning fluid, and first liquid drive unit 2, second liquid drive unit 3; Wherein this specimen needle fixed chamber is preferably flow chamber 10.
this specimen needle outlet 108 docking flow chamber entrance, this specimen needle entrance 109 is connected with the first sample and prepares pipeline 104 and the second sample preparation pipeline 106; This first liquid drive unit 2 is connected with first passage conversion and on-off controller 4, and the conversion of this first passage is connected liquid storage tank 1 with one end of on-off controller 4, and the other end connects flow chamber outlet 107; This second liquid drive unit 3 is connected with second channel conversion and on-off controller 5, and the conversion of this second channel is connected liquid storage tank 1 with one end of on-off controller 5, and the other end connects the first sample and prepares pipeline 104.
this cleaning device also comprises liquid container group, this liquid container group prepares pipeline 106 with this second sample and flow chamber entrance is connected, the break-make of pipeline 106 and flow chamber entrance is prepared for controlling this second sample, the cleaning fluid second sample being prepared to pipeline 106 and the conveying of flow chamber entrance stores, and the cleaning fluid loopback stored is prepared pipeline 106 and flow chamber entrance to the second sample.
specifically see Fig. 1, this liquid container group comprises first liquid container 7, second liquid container 8, first passage on-off controller 6, second channel on-off controller 9; This first liquid container 7 connects first passage on-off controller 6, path 10 5, flow chamber entrance successively, and this second liquid container 8 connects second channel on-off controller 9, second sample successively and prepares pipeline 106.
the cleaning method of the specimen needle of present embodiment and device can be applicable to blood cell, biochemistry, immunity at interior sample analyser.Carry out specimen needle 11 when cleaning, first liquid drive unit 2 draws cleaning fluid from liquid storage tank 1, and this cleaning fluid can be common measurement liquid, as dilution, also can be specific cleaning solution.After imbibition completes, first passage conversion and on-off controller 4 carry out passage bridge, the outlet of first liquid drive unit 2 is transferred to path 10 2 from path 10 1, second channel on-off controller 9 is opened simultaneously, second sample prepares pipeline 106 and second liquid container 8 conducting, under the driving of first liquid drive unit 2, its liquid inhaled is by path 10 2, flow chamber outlet 107 and 108 enter specimen needle 11 from specimen needle outlet, flow through the second sample preparation pipeline 106 from specimen needle entrance 109 subsequently and enter second liquid container 8, realize the back flush to specimen needle 11.
further, second liquid drive unit 3 draws cleaning fluid from liquid storage tank 1, after imbibition completes, second channel conversion and on-off controller 5 carry out passage bridge, the outlet of second liquid drive unit 3 is transferred to the first sample from path 10 3 and prepares pipeline 104, first passage on-off controller 6 is opened simultaneously, path 10 5 and first liquid container 7 conducting, under the driving of second liquid drive unit 3, its liquid inhaled prepares pipeline 104 by the first sample and enters specimen needle 11 from specimen needle entrance 109, flow through path 10 5 from specimen needle outlet 108 subsequently and enter first liquid container 7, realize rinsing the forward of specimen needle 11.
further, when carrying out specimen needle 11 back flush, by regulating the fluid injection time of first liquid drive unit 2, second liquid drive unit 3, fluid flow used can be cleaned to specimen needle 11 by control device.When carrying out specimen needle 11 back flush, by regulating the injection speed of first liquid drive unit 2, second liquid drive unit 3, control device is to the flowing velocity of specimen needle 11 cleaning liquid, coordinate the roughness of the length of specimen needle 11, internal diameter size and inner surface, the flow pattern of liquid in specimen needle 11 can be controlled, as laminar flow, turbulent flow, realize different cleaning performances.When carrying out specimen needle 11 and rinsing, by regulating the pattern of first liquid drive unit 2, second liquid drive unit 3, as played liquid, imbibition, the flow direction to specimen needle 11 cleaning liquid can be controlled, realizing the forward to specimen needle 11 and back flush.
further, first liquid drive unit 2, second liquid drive unit 3 draws cleaning fluid simultaneously from liquid storage tank 1, after imbibition completes, first passage conversion and on-off controller 4 and second channel change and on-off controller 5 carries out passage bridge respectively, first liquid drive unit 2 exports and is transferred to path 10 2 from path 10 1, second liquid drive unit 3 exports and is transferred to the first sample preparation pipeline 104 from path 10 3, second channel on-off controller 9 is opened simultaneously, second sample prepares pipeline 106 and second liquid container 8 conducting, under the driving of first liquid drive unit 2, its liquid inhaled is by path 10 2, flow chamber outlet 107 and 108 enter specimen needle 11 from specimen needle outlet, flow through the second sample preparation pipeline 106 from specimen needle entrance 109 subsequently and enter second liquid container 8.Simultaneously under the driving of second liquid drive unit 3, its liquid inhaled prepares pipeline 104, second sample preparation pipeline 106 by the first sample and enters second liquid container 8.Realize the back flush of specimen needle 11 simultaneously and the flushing that pipeline 104, second sample prepares pipeline 106 is prepared to the first sample, can scavenging period be saved, improve cleaning efficiency.
further, first liquid drive unit 2 draws cleaning fluid from liquid storage tank 1, after imbibition completes, first passage conversion and on-off controller 4 carry out passage bridge, the outlet of first liquid drive unit 2 is transferred to path 10 2 from path 10 1, second channel on-off controller 9 is opened simultaneously, second sample prepares pipeline 106 and second liquid container 8 conducting, under the driving of first liquid drive unit 2, its liquid inhaled is by path 10 2, flow chamber outlet 107 and 108 enter specimen needle 11 from specimen needle outlet, flow through the second sample preparation pipeline 106 from specimen needle entrance 109 subsequently and enter second liquid container 8, realize the back flush to specimen needle 11, the back flush duration is T1.Second channel on-off controller 9 is closed, first passage on-off controller 6 is opened simultaneously, path 10 5 and first liquid container 7 conducting, under the driving of second liquid drive unit 3, its liquid inhaled prepares pipeline 104 by the first sample and enters specimen needle 11 from specimen needle entrance 109, flow through path 10 5 from specimen needle outlet 108 subsequently and enter first liquid container 7, realize rinsing the forward of specimen needle 11, it is T2 that forward rinses the duration.Forward and back flush hocket, and can realize carrying out forward and reverse flushing in the mode of frequency T1/T2 or T2/T1 to specimen needle 11, strengthen cleaning performance.
fig. 2 is the second specific embodiment of the present invention, and the main distinction of this embodiment and the first embodiment is: the second embodiment does not have second liquid container 8, second channel on-off controller 9, first liquid container 7, first passage on-off controller 6.The conversion of corresponding increase third channel and on-off controller 13 and liquid container 12 UNICOM, under normality, third channel conversion and on-off controller 13 make path 10 5 and liquid container 12 conducting, can make the second sample preparation pipeline 106 and liquid container 12 conducting after switching.Increase pipeline between first passage conversion simultaneously and on-off controller 4, second channel conversion and on-off controller 5 export to connect, and use four-way on-off controller 15 to carry out break-make control.Change at first passage and increase third channel on-off controller 14 between on-off controller 4 and flow chamber outlet 107 simultaneously and carry out break-make control, under normality, third channel on-off controller 14 is off state, and other structures of this embodiment can be identical with the mode of the first embodiment.
carry out specimen needle 11 when cleaning, first liquid drive unit 2 draws cleaning fluid from liquid storage tank 1, after imbibition completes, first passage conversion and on-off controller 4 carry out passage bridge, the outlet of first liquid drive unit 2 is transferred to path 10 2 from path 10 1, third channel on-off controller 14 is opened simultaneously, path 10 2 and flow chamber is made to export 107 conductings, third channel conversion and on-off controller 13 switch makes the second sample prepare pipeline 106 and liquid container 12 conducting, under the driving of first liquid drive unit 2, its liquid inhaled is by path 10 2, flow chamber outlet 107 and 108 enter specimen needle 11 from specimen needle outlet, flow through the second sample preparation pipeline 106 from specimen needle entrance 109 subsequently and enter liquid container 12, realize the back flush to specimen needle 11.
further, second liquid drive unit 3 draws cleaning fluid from liquid storage tank 1, after imbibition completes, second channel conversion and on-off controller 5 carry out passage bridge, the outlet of second liquid drive unit 3 is transferred to the first sample from path 10 3 and prepares pipeline 104, under the driving of second liquid drive unit 3, its liquid inhaled prepares pipeline 104 by the first sample and enters specimen needle 11 from specimen needle entrance 109, flow through path 10 5 from specimen needle outlet 108 subsequently and enter liquid container 12, realize rinsing the forward of specimen needle 11.
further, when carrying out specimen needle 11 back flush, by regulating the fluid injection time of first liquid drive unit 2, second liquid drive unit 3, fluid flow used can be cleaned to specimen needle 11 by control device.When carrying out specimen needle 11 back flush, by regulating the injection speed of first liquid drive unit 2, second liquid drive unit 3, control device is to the flowing velocity of specimen needle 11 cleaning liquid, coordinate the roughness of the length of specimen needle 11, internal diameter size and inner surface, the flow pattern of liquid in specimen needle 11 can be controlled, as laminar flow, turbulent flow, realize different cleaning performances.When carrying out specimen needle 11 and rinsing, by regulating the pattern of first liquid drive unit 2, second liquid drive unit 3, as played liquid, imbibition, the flow direction to specimen needle 11 cleaning liquid can be controlled, realizing the forward to specimen needle 11 and back flush.
further, first liquid drive unit 2, second liquid drive unit 3 draws cleaning fluid simultaneously from liquid storage tank 1, after imbibition completes, first passage conversion and on-off controller 4 and second channel change and on-off controller 5 carries out passage bridge respectively, first liquid drive unit 2 exports and is transferred to path 10 2 from path 10 1, the outlet of second liquid drive unit 3 is transferred to the first sample from path 10 3 and prepares pipeline 104, third channel on-off controller 14 is opened simultaneously, path 10 2 and flow chamber is made to export 107 conductings, third channel conversion and on-off controller 13 switch makes the first sample prepare pipeline 104, second sample prepares pipeline 106 and liquid container 12 conducting, under the driving of first liquid drive unit 2, its liquid inhaled is by path 10 2, flow chamber outlet 107 and 108 enter specimen needle 11 from specimen needle outlet, flow through the second sample preparation pipeline 106 from specimen needle entrance 109 subsequently and enter liquid container 12.Realize the back flush of specimen needle 11 simultaneously and the flushing that pipeline 104, second sample prepares pipeline 106 is prepared to the first sample, can scavenging period be saved, improve cleaning efficiency.
further, first liquid drive unit 2 draws cleaning fluid from liquid storage tank 1, after imbibition completes, first passage conversion and on-off controller 4 carry out passage bridge, the outlet of first liquid drive unit 2 is transferred to path 10 2 from path 10 1, third channel on-off controller 14 is opened simultaneously, path 10 2 and flow chamber is made to export 107 conductings, third channel conversion and on-off controller 13 switch makes the second sample prepare pipeline 106 and liquid container 12 conducting, under the driving of first liquid drive unit 2, its liquid inhaled is by path 10 2, flow chamber outlet 107 and 108 enter specimen needle 11 from specimen needle outlet, flow through the second sample preparation pipeline 106 from specimen needle entrance 109 subsequently and enter liquid container 12, realize the back flush to specimen needle 11, the back flush duration is T1.Second liquid drive unit 3 draws cleaning fluid from liquid storage tank 1, after imbibition completes, second channel conversion and on-off controller 5 carry out passage bridge, the outlet of second liquid drive unit 3 is transferred to the first sample from path 10 3 and prepares pipeline 104, under the driving of second liquid drive unit 3, its liquid inhaled prepares pipeline 104 by the first sample and enters specimen needle 11 from specimen needle entrance 109, flow through path 10 5 from specimen needle outlet 108 subsequently and enter liquid container 12, realize rinsing the forward of specimen needle 11, it is T2 that forward rinses the duration.Forward and back flush hocket, and can realize carrying out forward and reverse flushing in the mode of frequency T1/T2 or T2/T1 to specimen needle 11, strengthen cleaning performance.
further, first liquid drive unit 2 draws cleaning fluid from liquid storage tank 1, after imbibition completes, first passage conversion and on-off controller 4 carry out passage bridge, the outlet of first passage conversion and on-off controller 4 is made to be transferred to passage 110 from path 10 1, third channel conversion and on-off controller 13 switch makes the second sample prepare pipeline 106 and liquid container 12 conducting, third channel on-off controller 14 is closed simultaneously, four-way on-off controller 15 is opened, now the outlet of first liquid drive unit 2 is through passage 110, 111, first sample prepares pipeline 104, second sample prepares pipeline 106 and enters liquid container 12, under the driving of first liquid drive unit 2, its liquid inhaled is by realizing the flushing the first sample being prepared to pipeline 104 and the second sample preparation pipeline 106 with upper channel.
further, first liquid drive unit 2 draws cleaning fluid from liquid storage tank 1, after imbibition completes, first passage conversion and on-off controller 4 carry out passage bridge, third channel on-off controller 14 is closed simultaneously, four-way on-off controller 15 is opened, make the outlet of first liquid drive unit 2 through passage 110, 111 and first sample prepare pipeline 104 enter specimen needle 11 from specimen needle entrance 109, flow through path 10 5 from specimen needle outlet 108 subsequently and enter liquid container 12, under the driving of first liquid drive unit 2, its liquid inhaled is by realizing rinsing the forward of specimen needle 11 with upper channel.
the foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, all any amendments done within the spirit and principles in the present invention, equivalent replacement and improvement etc., all should be included within protection scope of the present invention.
Claims (7)
1. a cleaning device for specimen needle, is characterized in that, comprising: specimen needle, specimen needle fixed chamber specimen needle be fixed, built with the liquid storage tank of cleaning fluid, and first liquid drive unit, second liquid drive unit;
The outlet docking specimen needle fixed chamber entrance of described specimen needle, the entrance of described specimen needle is connected with the first sample and prepares pipeline and the second sample preparation pipeline; Described first liquid drive unit is connected with first passage conversion and on-off controller, and described first passage conversion is connected liquid storage tank with one end of on-off controller, and the other end connects the outlet of specimen needle fixed chamber; Described second liquid drive unit is connected with second channel conversion and on-off controller, and described second channel conversion is connected liquid storage tank with one end of on-off controller, and the other end connects the first sample and prepares pipeline;
Described cleaning device also comprises liquid container group, described liquid container group prepares pipeline with described second sample and specimen needle fixed chamber entrance is connected, the break-make of pipeline and specimen needle fixed chamber entrance is prepared for controlling described second sample, the cleaning fluid second sample being prepared to pipeline and the conveying of specimen needle fixed chamber entrance stores, and the cleaning fluid loopback stored is prepared pipeline and specimen needle fixed chamber entrance to the second sample.
2.
the cleaning device of a kind of specimen needle according to claim 1, is characterized in that, described liquid container group comprises first liquid container, second liquid container, first passage on-off controller, second channel on-off controller; Described first liquid container connects first passage on-off controller, specimen needle fixed chamber entrance successively, and described second liquid container connects second channel on-off controller successively, the second sample prepares pipeline.
3.
the cleaning device of a kind of specimen needle according to claim 1, is characterized in that, described liquid container group comprises liquid container, and the third channel be connected with this liquid container is changed and on-off controller; It is described that third channel conversion is connected specimen needle fixed chamber entrance respectively with the two ends of on-off controller, the second sample prepares pipeline.
4.
the cleaning device of a kind of specimen needle according to any one of claim 1-3, is characterized in that, described specimen needle fixed chamber is flow chamber.
5.
the cleaning device of a kind of specimen needle according to claim 4, it is characterized in that, the other end of the conversion of described first passage and on-off controller to be exported with specimen needle fixed chamber by third channel on-off controller and is connected, and passes through four-way on-off controller and to change with second channel and the other end of on-off controller is connected.
6.
application rights requires a method for the cleaning device of a kind of specimen needle described in 1, it is characterized in that, comprises the following steps:
after first liquid drive unit draws cleaning fluid from liquid storage tank, first passage conversion and on-off controller carry out passage bridge, cleaning fluid enters specimen needle by the outlet of specimen needle fixed chamber under the driving of first liquid drive unit, flow through the second sample preparation pipeline from specimen needle entrance subsequently and enter liquid container group, back flush is carried out to specimen needle; While back flush is carried out to specimen needle, second liquid drive unit draws cleaning fluid from liquid storage tank, second channel conversion and on-off controller carry out passage bridge, cleaning fluid flows through the first sample preparation pipeline under the driving of second liquid drive unit, the second sample prepares pipeline and enters liquid container group, prepares pipeline rinse specimen needle and first and second sample;
after second liquid drive unit draws cleaning fluid from liquid storage tank, second channel conversion and on-off controller carry out passage bridge, cleaning fluid flows through the first sample preparation pipeline under the driving of second liquid drive unit, specimen needle entrance enters specimen needle, flow through specimen needle outlet subsequently, specimen needle fixed chamber entrance enters liquid container group, carries out forward flushing to specimen needle;
the time of described specimen needle back flush is preset time value T1, and the time that described specimen needle forward rinses is preset time value T2; Described cleaning method hockets according to T1/T2 or T2/T1 hockets.
7.
the cleaning method of a kind of specimen needle according to claim 6, is characterized in that, described cleaning fluid is diluent or cleaning agent.
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| CN104690044B (en) * | 2015-03-09 | 2016-08-24 | 北京普立泰科仪器有限公司 | A kind of active sampling probe preventing cross-contamination cleans device and cleaning method |
| JP7365504B2 (en) * | 2020-05-19 | 2023-10-19 | ライフ テクノロジーズ コーポレーション | Nozzle seal and clog removal station for flow cytometers |
| CN113714215A (en) * | 2021-08-25 | 2021-11-30 | 宁波江丰电子材料股份有限公司 | Cleaning method of cooling disc for semiconductor |
| CN114589636B (en) * | 2022-03-14 | 2023-02-17 | 陕西捷特智能科技有限公司 | Device and method for cleaning inner flow channel of 3D complex part based on magnetic guiding pneumatic reciprocating jet flow |
| CN116359524B (en) * | 2023-05-31 | 2023-09-15 | 深圳市帝迈生物技术有限公司 | Sample detection device |
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| CN201974434U (en) * | 2011-02-14 | 2011-09-14 | 四川迈克生物科技股份有限公司 | Automation device for fast cleaning sample needles |
| CN103389265A (en) * | 2013-07-30 | 2013-11-13 | 济南华天恒达科技有限公司 | Sampling and washing system |
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| JP2008058163A (en) * | 2006-08-31 | 2008-03-13 | Hitachi High-Technologies Corp | Automalyzer |
| AU2009222111A1 (en) * | 2008-02-29 | 2009-09-11 | Beckman Coulter, Inc. | Apparatus and method for cleaning a liquid handling probe |
| JP2010216876A (en) * | 2009-03-13 | 2010-09-30 | Beckman Coulter Inc | Analyzer and dispensing probe washing method |
| JP5924113B2 (en) * | 2012-05-15 | 2016-05-25 | 株式会社島津製作所 | Needle cleaning mechanism |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN201974434U (en) * | 2011-02-14 | 2011-09-14 | 四川迈克生物科技股份有限公司 | Automation device for fast cleaning sample needles |
| CN103389265A (en) * | 2013-07-30 | 2013-11-13 | 济南华天恒达科技有限公司 | Sampling and washing system |
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