CN106771293B - Automatic clinical chemistry analyzer with allocation unit - Google Patents

Automatic clinical chemistry analyzer with allocation unit Download PDF

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Publication number
CN106771293B
CN106771293B CN201710034197.4A CN201710034197A CN106771293B CN 106771293 B CN106771293 B CN 106771293B CN 201710034197 A CN201710034197 A CN 201710034197A CN 106771293 B CN106771293 B CN 106771293B
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needle
cleaning
reagent
sample
allocation unit
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CN106771293A (en
Inventor
徐新
宋成桥
张陆军
缪建
潘有铭
纪本奎
郭敏
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Sinnowa Medical Science & Technology Co.,Ltd.
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Jiangsu Ke Lundi Medical Technology Co Ltd
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/026—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0401—Sample carriers, cuvettes or reaction vessels
    • G01N2035/0437—Cleaning cuvettes or reaction vessels

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The invention discloses a kind of automatic clinical chemistry analyzers with allocation unit, the instrument includes reagent disc, reaction tray, agitating unit, sample load units, more than one allocation unit, detection cup cleaning unit, optical detection unit and control and data analysis and processing unit, allocation unit includes more than one middle empty needle, a pipeline converter, needle interior cleaning apparatus, needle exterior washings device, waste collection slot and needle mobile device, for drawing distribution reagent and sample, it is either individually used for drawing distribution reagent or individually draws distribution sample.The automatic clinical chemistry analyzer of the present invention solves different reagents, sample room cross-contamination issue caused by traditional automatic clinical chemistry analyzer is not thorough due to reagent needle, sample needle internal washing, improves the accuracy and reliability of Instrumental results.

Description

Automatic clinical chemistry analyzer with allocation unit
Technical field
The invention belongs to medical test detection technique field, especially a kind of full-automatic biochemical analysis with allocation unit Instrument.
Background technology
Automatic clinical chemistry analyzer is the common detection device of medical institutions.Main problem in this existing quasi-instrument use One of be exactly due to usually needing using a variety of different reagents, the different samples of detection in detecting, and instrument is all made of shared examination Agent needle and sample needle draw different reagents respectively and different samples are added in each detection cup and are measured, and are drawing reagent and sample When, inside and outside, usually remaining reagent and the sample especially inside needle of reagent needle and sample needle, and be difficult to thoroughly clean, in addition Medical laboratory instrument is required to be run according to higher speed, therefore, often without time enough to reagent needle and sample needle It is inside and outside thoroughly to be cleaned, and remaining reagent or sample is caused to form interference to subsequent detection.And it is adopted in instrument operation Although can effectively lower or avoid this kind of cross contamination with the mode being cleaned multiple times, instrument detection is directly resulted in this way Speed substantially reduces.
Also there is the method that sample or reagent are drawn using disposable tip in the prior art, but due to drawing examination every time As soon as agent, sample are required for abandoning a used tip, this needs larger space to store a large amount of disposable tip just now It may insure that instrument is on duty without operating personnel, and required consumable quantity is very huge when the instrument operation of the design.
Invention content
The purpose of the present invention is to provide a kind of automatic clinical chemistry analyzers with allocation unit, solve existing full-automatic The cross-contamination issue of biochemical analyzer reagent needle and sample needle.
Realize that the technical solution of the object of the invention is：A kind of automatic clinical chemistry analyzer with allocation unit, feature It is, which includes reagent disc, reaction tray, agitating unit, sample load units, more than one allocation unit, detection cup Cleaning unit, optical detection unit and control and data analysis and processing unit；
The reagent disc is for placing reagent, and the sample load units are for placing sample, and the reaction tray is for putting Set detection cup；
The allocation unit for drawing and distribute reagent or sample, including more than one middle empty needle, pipeline converter, Needle mobile device and waste collection slot；The pipeline converter includes a working position and more than one cleaning position, working position With a middle empty needle is respectively set on each cleaning position, it is each in empty needle in working position and cleaning interdigit switching；The working position It is provided with outside needle interior cleaning apparatus and needle for addition reagent or sample, the cleaning position in the middle empty needle on reagent position Cleaning device, for being cleaned to middle empty needle is inside and outside on cleaning position；The needle mobile device is for driving reagent position On middle empty needle moved between working position and reagent disc, sample disc, detection cup；The waste collection slot setting turns in pipeline Below parallel operation, for collecting waste liquid；
The optical detection unit is for being detected liquid in detection cup, and the detection cup cleaning unit is for cleaning Detection cup；
The control and data analysis and processing unit are used to control analyzer each unit cooperating, and to optical detection list First detection data carries out analyzing processing.
Compared with prior art, remarkable result of the invention is：
There is the present invention automatic clinical chemistry analyzer of allocation unit can not extend scavenging period, ensure that instrument works Under the premise of speed, the residual of reagent and sample is realized fully and effective clear inside and outside the needle to drawing reagent and pipette samples It washes, substantially reduces and even be eliminated the cross contamination that other same quasi-instruments are formed in the link, and is dirty to intersect in various degree Dye processing provides the solution of multiple modes, therefore has preferable convenience, feasibility, economy and validity.
Description of the drawings
Fig. 1 is a kind of structural schematic diagram of automatic clinical chemistry analyzer with allocation unit of the present invention, sample in figure Load units are circular sample disk.
Fig. 2 is a kind of structural schematic diagram of automatic clinical chemistry analyzer with allocation unit of the present invention, sample in figure Load units are rail mounted specimen holder.
Fig. 3-1 is pipeline converter schematic top plan view.
Fig. 3-2 is pipeline converter schematic cross-sectional view.
Fig. 3-3 is pipeline converter working position structural schematic diagram.
Fig. 3-4 is the first cleaning position of pipeline converter structural schematic diagram.
Fig. 3-5 is the second cleaning position of pipeline converter structural schematic diagram.
Fig. 3-6 is pipeline converter third cleaning position structural schematic diagram.
Fig. 3-7 is the schematic top plan view of the waste collection slot of allocation unit.
Fig. 4-1~Fig. 4-3 be allocation unit needle mobile device from working position taking-up in empty needle process schematic, Fig. 4- 4~Fig. 4-6 is that middle empty needle is put back to the process schematic of working position by the needle mobile device of allocation unit.
Fig. 5 is a kind of structural schematic diagram of embodiment of allocation unit of the present invention.
Specific embodiment mode
In conjunction with Fig. 1, Fig. 2, a kind of automatic clinical chemistry analyzer with allocation unit of the invention, which includes reagent Disk 1, reaction tray 5, agitating unit, sample load units, more than one allocation unit, detection cup cleaning unit 2B, optics inspection Survey unit and control and data analysis and processing unit；
The reagent disc 1 is for placing reagent, and for placing sample, the reaction tray 5 is used for the sample load units Place detection cup 6；
The allocation unit is for drawing and distributing reagent or sample, including the conversion of more than one middle empty needle 7-6, pipeline Device 4, needle mobile device and waste collection slot 7-4；The pipeline converter 4 includes a working position and more than one cleaning , a middle empty needle 7-6 is respectively set on working position and each cleaning position, each middle empty needle 7-6 is in working position and cleaning interdigit Switching；The working position is provided with for addition reagent in the middle empty needle 7-6 on reagent position or sample, the cleaning position in needle Portion's cleaning device and needle exterior washings device, for being cleaned to middle empty needle 7-6 is inside and outside on cleaning position；The needle moves Dynamic device is for driving the middle empty needle 7-6 on reagent position between working position and reagent disc 1, sample load units, detection cup 6 It is mobile；The waste collection slot 7-4 is arranged below pipeline converter 4, for collecting waste liquid；
The optical detection unit is for being detected liquid in detection cup 6, and the detection cup cleaning unit is for clear Wash detection cup；
The control and data analysis and processing unit are used to control analyzer each unit cooperating, and to optical detection list First detection data carries out analyzing processing.
Further, the pipeline converter 4 of the allocation unit includes that runner 7-1, fixed block 7-2 and pipeline converter drive Dynamic motor 7-3；The runner 7-1 is arranged on fixed block 7-2, is close to fixed block 7-2, the pipeline converter driving motor The shaft of 7-3 is connect across fixed block centre bore with runner 7-1, drives runner 7-1 rotations；The runner 7-1 and fixed block 7-2 Corresponding position is provided with no less than two channels；When runner 7-1 rotates stopping every time, each channel on runner and fixed block 7-2 Each corresponding channel communicates, and not corresponding interchannel is not connected；The port number of port number, fixed block 7-2 on runner 7-1 with should Middle empty needle quantity is identical on allocation unit device, is connect with middle empty needle by pipeline 7-5 above the channel on the runner 7-1, Below each channel on the fixed block 7-2 by pipeline respectively with a fixed-quantity injector SAIt is injected with more than one cleaning Device connects；
When empty needle 7-6 is in working position in the middle, fixed-quantity injector SABy fixed block channel, runner channel with it is corresponding in Empty needle communicates；When middle empty needle 7-6 is in cleaning position, syringe is cleaned to corresponding fixed block channel, runner channel and middle empty needle Injection cleaning agent, water, physiological saline or air, centering empty needle are cleaned.
Further, the fixed-quantity injector SAInterface connected by channel on fixed block channel and runner and middle empty needle It is logical, while being connect with cup by another pipeline, the first valve V is provided on the pipeline being connect with cup1A, with fixed block- It is provided with the second valve V on the pipeline of runner-hollow needle passage connection2A, close the first valve V1A, open simultaneously the second valve V2A, fixed-quantity injector, which can quantify, extracts and is discharged reagent or sample；Close the second valve V2A, open simultaneously the first valve V1A, fixed The water in syringe extraction cup is measured, closes the first valve V later1A, open simultaneously the second valve V2A, it pushes away on fixed-quantity injector, Empty needle is expelled in waste collection slot during water is passed through by pipeline.
Further, the needle mobile device includes moving arm 2A, handgrip 2-1, the drivings of the first driving motor 2M1 and second Motor 2M2, the handgrip 2-1 settings are in the front ends moving arm 2A, and the first driving motor 2M1 is for driving handgrip relative to moving arm It is moved forward and backward, the second driving motor 2M2 is for driving handgrip to clamp and extend out, and the moving arm 2A is for driving needle mobile device It is moved between working position, reagent disc and detection cup.
Further, the needle exterior washings device includes cleaning agent spout 7-9 and pure water spout 7-8, two spouts It is directed to the tip of middle empty needle, and pure water spout 7-8 is higher than the positions cleaning agent spout 7-9, it is clear that when use first passes through cleaning agent 7-9 wash hair to jet cleaner on the outside of hollow needle point, is then sprayed to hollow needle point outside by pure water spout 7-8 pure Water；Cleaning agent and pure water after flushing are fallen into the waste collection slot of lower section.
Further, the needle exterior washings device includes pure water spout 7-8, and the tip of empty needle during spout is directed toward leads to It crosses on the outside of hollow needle point outside injection pure water cleaning needle point；Pure water after flushing is fallen into the waste collection slot of lower section.
Further, the allocation unit further includes the outer water sweeper 7-10 of needle, between needle cleaning position and working position, For clearing up the needle appearance ponding after cleaning.
Further, which includes an allocation unit, and the allocation unit is simultaneously for distributing reagent and sample.
Further, the automatic clinical chemistry analyzer further includes sample needle, for shifting sample in sample load units Into detection cup.
Further, which includes two allocation units, and one of allocation unit is for distributing reagent and sample, separately One allocation unit is only used for distribution reagent.
The present invention is described further with reference to the accompanying drawings and examples.
Embodiment 1
Fig. 1 is the one embodiment for the automatic clinical chemistry analyzer that the present invention has allocation unit.
The primary structure of the instrument includes two reagent discs 1, reaction tray 5, sample load units, optical detection unit, inspection Cup cleaning unit 2B, 2 allocation units and a sample needle 2C are surveyed, sample load units use circular sample disk 3；Two distribution Unit is for drawing and distributing reagent, and sample needle 2C is for drawing sample；It is provided with cleaning position 2D by sample needle 2C, for cleaning Sample needle 2C.
Wherein, multiple reagent bottle 1-1 are provided on reagent disc 1, reaction tray 5 is equipped with multiple detection cups 6, optical detection list Member includes light source 5A, monochromator 5B and optical signal detector 5C；
Allocation unit includes needle moving arm 2A/2A ', pipeline converter and waste collection slot, and pipeline converter includes runner 7-1, fixed block 7-2 and pipeline converter driving motor 7-3；Runner 7-1 is arranged on fixed block 7-2, tight with fixed block 7-2 Patch, the shaft of the pipeline converter driving motor 7-3 are connect across fixed block centre bore with runner 7-1, and runner 7-1 is driven to turn It is dynamic；
One allocation unit is set close to the first positions reagent disc R1, the pipeline converter 4 of the allocation unit includes work A needle position is arranged in position, the first cleaning position, the second cleaning position and third cleaning position, each working position and cleaning position, corresponds to respectively Working position needle position A1, the first cleaning position needle position B1, the second cleaning position needle position C1 and third cleaning position needle position D1, each needle position are run through Runner 7-1, and it is provided with hollow needle stand 7-7 on each needle position, place a middle empty needle 7-6 on each hollow needle stand 7-7；
As shown in Fig. 3-1- Fig. 3-6, it is provided with pipe-line system by each needle position, includes first turn on runner 7-1 Take turns channel A2, the second runner channel B2, third runner channel C 2, the 4th runner channel D2 and it is upper positioned at fixed block 7-2 and with turn Wheel 7-1 upper channels position corresponding first fixed block channel A, the second fixed block channel B, third fixed block channel C, the 4th consolidate Determine block channel D；And A1-A2, B1-B2, C1-C2, D1-D2 are corresponding with pipeline and are connected.
When motor 7-3 rotations can then drive top runner 7-1 to rotate, the needle being fixed on runner 7-1 also converts position, Simultaneously because fixed block 7-2 does not rotate, therefore when each runner 7-1 rotations, on the upper four needle positions runner 7-1 and fixed block Each channel all synchronize and change, it is ensured that A1 needles are used to draw always reagent or sample, and other three positions Needle is then in cleaning state.Empty needle is then converted by pipeline converter to the first cleaning position after the A1 uses of working position needle position in the middle Needle position B1 starts to clean, and corresponding original is in the first cleaning position needle position B1, the second cleaning position needle position C1 and third cleaning position needle position D1 Middle empty needle is in same direction along moving one, in the first cleaning position needle position B1, the second cleaning position needle position C1 and third cleaning position needle position D1 distinguishes centering empty needle and is once cleaned, and the middle empty needle for being eventually transferred into working position needle position A1 passes through inside and outside such process clearly It washes.
Fig. 3-3 is pipeline converter working position structural schematic diagram, wherein the first valve V1AFor fixed-quantity injector SAConnecting tube The pipeline valve of water is led in road；Second valve V2AFor fixed-quantity injector SAValve in piping connection to middle empty needle access.Fig. 3-4 For the first cleaning position of pipeline converter structural schematic diagram, wherein third valve V1BFor the first cleaning syringe SBLead on connecting line To cleaning agent or the pipeline valve of water or physiological saline or air；4th valve V2BFor empty needle access in syringe piping connection On valve.The second cleaning position of Fig. 3-5 pipelines converter structural schematic diagram, wherein the 5th valve V1CFor the second cleaning syringe SC Lead on connecting line or the pipeline valve of cleaning agent or water or physiological saline or air；6th valve V2CFor syringe pipeline Valve in connection on empty needle access.Fig. 3-6 pipeline converter thirds cleaning position structural schematic diagram, wherein the 7th valve V1DIt is Three cleaning syringe SDLead on connecting line or the pipeline valve of cleaning agent or water or physiological saline or air；8th valve V2D For the valve on empty needle access in syringe piping connection.
As shown in figure 3-2, pipeline converter lower part is provided with waste collection slot 7-4, fixed-quantity injector SAFor drawing simultaneously Distribute reagent, the first cleaning syringe SBCleaning agent, water or air are perfused when for cleaning needle.Such as Fig. 3-3, fixed-quantity injector SA Operation principle is：The middle empty needle of working position needle position A1 enters under the driving of needle mobile device in reagent bottle, closes the first valve V1A, open the second valve V2A, fixed-quantity injector SAPiston pumpback, reagent suck in needle；When needle is moved down in the driving of needle mobile device It moves to detection cup position, fixed-quantity injector SAPiston above push away, then in needle reagent injection detection cup in.Fixed-quantity injector SAIn instrument The preproduction phase of device unlatching or certain link in work, open the first valve V1A, close the second valve V2A, fixed-quantity injector SAIt is living Pumping is got back into, water is sucked in syringe；It is then turned off the first valve V1A, open the second valve V2A, push away on syringe piston so that Syringe and pipeline A-A2-A1 are filled with water.Such as Fig. 3-4, the first cleaning syringe SBWhen work, the 4th valve V is closed2B, open Open third valve V1B, syringe piston pumpback, cleaning agent or water enter the first cleaning syringe SBIt is interior；Later on 4th valve V2B, close third valve V1B, the first cleaning syringe SBIt is pushed away on piston, liquid enters pipeline B-B2-B1 in syringe, realizes The middle empty needle of first cleaning position needle position B1 cleans.
Another allocation unit, the pipeline conversion of the allocation unit are set close to the second positions reagent disc R2 in the instrument Device only has 2 needle positions, i.e. working position needle position A1 and cleaning position needle position B1, the two needle positions are always in turn by one of them middle empty needle When for working, empty needle is then in cleaning state in another.
Each detection cup in reaction tray 5 receives the first reagent at the first detection cup position RC1 always, in the second detection cup position Receive sample at RC2, first time stirring is carried out at third detection cup position RC3, part double reagent detection project is in the 4th detection Receive the second reagent at cup position RC4, second is carried out at the 5th detection cup position RC5 later stirs.It is reacted when instrument is run Disk 5 every time turn around and stop after+1 by rotation, as soon as therefore detection cup position often rotate it is primary just move forward, in reaction tray rotary course According to sequence reagent 1, sample are added in detection cup, be stirred later, selectively add or be added without reagent 2.Adding After entering reagent 2, agitating device is again stirring for liquid in detection cup, is all detected to detection cup when reaction tray rotates every time, Each detection cup is obtained before and after reagent 1 is added, is added after serum, the absorbance value of liquid in detection cup after reagent 2 is added, The last absorbance data according to each detection cup of overall process detection acquisition, analysis obtain the biochemical inspection of projects in different samples Survey result.
Embodiment 2
Such as Fig. 2, the present embodiment is with embodiment 1 the difference lies in that the sample load units of the embodiment are track style Product frame 8, and have there are two allocation unit, close to the first positions reagent disc R1, there are one allocation unit, the pipelines of the allocation unit There are three needle positions for converter tool；Close to the second positions reagent disc R2, there are one allocation unit, the pipeline converters of the allocation unit With two needle positions.
Embodiment 3
As shown in Figure 3-4, in the present embodiment, the cleaning of needle is not limited only to inside needle in the allocation unit, further includes Cleaning outside needle, needle exterior washings device includes cleaning agent spout 7-9 and pure water spout 7-8, during two spouts are directed to The tip of empty needle, and pure water spout 7-8 is higher than the positions cleaning agent spout 7-9, when use first pass through cleaning agent cleaning head 7-9 to Then jet cleaner on the outside of hollow needle point sprays pure water by pure water spout 7-8 to hollow needle point outside；After flushing Cleaning agent and pure water are fallen into the waste collection slot of lower section.
Alternatively, pure water spout 7-8 is only arranged outside middle empty needle, as in Figure 3-5.
Embodiment 4
Such as Fig. 3-6 and Fig. 3-7, in the present embodiment, pipeline converter corresponds to waste collection slot respectively below four needle positions Four positions of 7-4, respectively the first waste collection slot waste collection slot position D3 of position A3~the 4th, in the 4th waste collection slot position The outer water sweeper 7-10 of a pair of of needle is equipped between D3 and the first waste collection slot position A3, when middle empty needle 7-6 passes through herein, outside needle The ponding hung on empty needle outer wall during water sweeper 7-10 is removed automatically.
Waste collection slot 7-4 is provided with waste liquid port 7-11, and all waste liquids pass through a waste liquid port 7-11 discharge.
Embodiment 5
As shown in Fig. 4-1~Fig. 4-6 and Fig. 1, embodiment provides a kind of specific needle mobile device structure and its work Principle.
Needle mobile device includes moving arm 2A, handgrip 2-1, the first driving motor 2M1 and the second driving motor 2M2, described In the front ends moving arm 2A, the first driving motor 2M1 is used to that handgrip to be driven to be moved forward and backward relative to moving arm for handgrip 2-1 settings, the Two driving motor 2M2 are for driving handgrip to clamp and extend out, and the moving arm 2A is for driving needle mobile device in working position, examination It is moved between agent disk and detection cup.
In crawl when empty needle, as shown in Fig. 4-1~Fig. 4-3, empty needle during the second driving motor 2M2 driving handgrips 2-1 is clamped, The first driving motor 2M1 driving handgrip removes middle empty needle from needle stand simultaneously, and moving arm 2A drives handgrip 2-1 later, will in Empty needle is moved in reagent disc 1 in reagent bottle 1-1 from working position and draws reagent.
When putting back to middle empty needle, as shown in Fig. 4-4~Fig. 4-6, moving arm 2A drives handgrip 2-1 that middle empty needle is moved to detection 6 top of cup, the reagent of absorption is distributed into detection cup 6, moving arm 2A is moved to working position, the first driving motor 2M1 later Middle empty needle is placed in needle stand position by driving handgrip, while the second driving motor 2M2 drivings handgrip 2-1 is extended out.
Embodiment 6
As shown in figure 5, in this embodiment, using same middle empty needle distribution reagent and sample.
The needle mobile device of the present embodiment further includes moving arm pedestal 2L, third driving motor 2G, the 4th driving motor 2F It is arranged in moving arm pedestal 2L with shaft 2K, the third driving motor 2G and the 4th driving motor 2F, the shaft 2K's One end is connect with moving arm 2A, and the other end is connect with third driving motor 2G and the 4th driving motor 2F respectively, third driving electricity Machine 2G is moved up and down for controlling moving arm rotation, the 4th driving motor 2F for controlling moving arm.
Handgrip 2-1 in needle mobile device removes middle empty needle 7-6 from 4 working position of pipeline converter, moving arm 2A bands Middle empty needle 7-6 is transferred to reagent position by dynamic handgrip 2-1, closes the first valve V1A, open the second valve V2A, fixed-quantity injector SAIt is living Pumping is got back into, reagent is drawn into middle empty needle 7-6；Moving arm 2A drives handgrip 2-1 that middle empty needle 7-6 is moved to detection cup position, Fixed-quantity injector SAIt is pushed away on piston, reagent is distributed into detection cup, realize reagent distribution, moving arm 2A drives handgrip will later Middle empty needle is transferred to working position.
Close the second valve V2A, open the first valve V1A, fixed-quantity injector SAWater is sucked fixed-quantity injector by piston pumpback SAIt is interior；Close the first valve V1A, open the second valve V2A, fixed-quantity injector SAIt is pushed away on piston, water empty needle 7- along pipeline entrance 6, it is cleaned inside centering empty needle；Middle empty needle is placed in cleaning position by the rotation of pipeline converter 4 simultaneously, and the outer washer of needle is to hollow It is cleaned outside needle.After cleaning, handgrip 2-1 in needle mobile device is by cleaned middle empty needle 7-6 from pipeline converter 4 It is removed on working position, moving arm 2A drives handgrip that middle empty needle is transferred to sample position, closes the first valve V1A, open the second valve V2A, fixed-quantity injector SAPiston pumpback draws sample into middle empty needle 7-6；Moving arm 2A drives handgrip 2-1 by middle empty needle 7- 6 are moved to detection cup position, fixed-quantity injector SAIt is pushed away on piston, sample is distributed into detection cup, realize sample distribution.It manages later Needle is placed in cleaning position by the rotation of road converter 4, and the outer washer of needle outside needle to cleaning.
Embodiment 7
Difference lies in empty needle 7-6 is individually in sample position and detection during needle mobile device drives with embodiment 6 for the present embodiment It is moved between cup, realizes sample distribution.
Embodiment 8
Difference lies in empty needle 7-6 is individually in reagent position and detection during needle mobile device drives with embodiment 6 for the present embodiment It is moved between cup, realizes reagent distribution.
The present invention provides a kind of automatic clinical chemistry analyzer with allocation unit, the above is only the excellent of the present invention Select embodiment, it is noted that for those skilled in the art, in the premise for not departing from the principle of the invention Under, several improvements and modifications can also be made, these improvements and modifications also should be regarded as protection scope of the present invention.In the present embodiment The available prior art of each component part not yet explicitly is realized.

Claims (9)

1. a kind of automatic clinical chemistry analyzer with allocation unit, which is characterized in that the instrument includes reagent disc (1), reaction Disk (5), agitating unit, sample load units, more than one allocation unit, detection cup cleaning unit (2B), optical detection list Member and control and data analysis and processing unit；
The reagent disc (1) is for placing reagent, and for placing sample, the reaction tray (5) is used for the sample load units Place detection cup (6)；
The allocation unit is for drawing and distributing reagent or sample, including more than one middle empty needle (7-6), pipeline converter (4), needle mobile device and waste collection slot (7-4)；The pipeline converter (4) includes a working position and more than one clear Position is washed, a middle empty needle (7-6) is respectively set on working position and each cleaning position, each middle empty needle (7-6) is in working position and clearly Wash interdigit switching；The working position is set for addition reagent in the middle empty needle (7-6) on reagent position or sample, the cleaning position It is equipped with needle interior cleaning apparatus and needle exterior washings device, is carried out clearly for inside and outside to middle empty needle (7-6) on cleaning position It washes；The needle mobile device is used to drive the middle empty needle (7-6) on reagent position to be loaded in working position and reagent disc (1), sample Unit, detection cup move between (6)；Waste collection slot (7-4) setting is useless for collecting below pipeline converter (4) Liquid；
The pipeline converter (4) of the allocation unit includes runner (7-1), fixed block (7-2) and pipeline converter driving motor (7-3)；The runner (7-1) is arranged on fixed block (7-2), is close to fixed block (7-2), the pipeline converter driving electricity The shaft of machine (7-3) is connect across fixed block centre bore with runner (7-1), and runner (7-1) is driven to rotate；The runner (7-1) Fixed block (7-2) corresponding position is provided with no less than two channels；It is each on runner when runner (7-1) rotates stopping every time Channel is communicated with fixed block (7-2) each corresponding channel, and not corresponding interchannel is not connected；It is port number on runner (7-1), solid The port number for determining block (7-2) is identical as middle empty needle quantity on the allocation unit device, logical above the channel on the runner (7-1) It crosses pipeline (7-5) to connect with middle empty needle, quantitatively be noted with one respectively by pipeline below each channel on the fixed block (7-2) Emitter (SA) connected with more than one cleaning syringe；
When empty needle (7-6) is in working position in the middle, fixed-quantity injector (SA) by fixed block channel, runner channel with it is corresponding in Empty needle communicates；When middle empty needle (7-6) is in cleaning position, cleaning syringe is to corresponding fixed block channel, runner channel and hollow Needle injection cleaning agent, water, physiological saline or air, centering empty needle are cleaned；
The optical detection unit is for being detected liquid in detection cup (6), and the detection cup cleaning unit is for cleaning Detection cup；
The control and data analysis and processing unit are examined for controlling analyzer each unit cooperating, and to optical detection unit Measured data carries out analyzing processing.
2. the automatic clinical chemistry analyzer according to claim 1 with allocation unit, which is characterized in that the quantitative note Emitter (SA) interface be connected to middle empty needle by the channel on fixed block channel and runner, while passing through another pipeline and cup Connection, is provided with the first valve (V on the pipeline being connect with cup1A), the pipe being connect with fixed block-runner-hollow needle passage Road is provided with the second valve (V2A), close the first valve (V1A), open simultaneously the second valve (V2A), fixed-quantity injector can be determined Amount extracts and is discharged reagent or sample；Close the second valve (V2A), open simultaneously the first valve (V1A), fixed-quantity injector extracts Water in cup closes the first valve (V later1A), open simultaneously the second valve (V2A), it pushes away on fixed-quantity injector, water passes through pipe Lu Jingzhong empty needles are expelled in waste collection slot.
3. the automatic clinical chemistry analyzer according to claim 1 with allocation unit, which is characterized in that the needle movement Device includes moving arm (2A), handgrip (2-1), the first driving motor (2M1) and the second driving motor (2M2), the handgrip (2- 1) setting is in the front end moving arm (2A), and the first driving motor (2M1) is for driving handgrip to be moved forward and backward relative to moving arm, and second Driving motor (2M2) for drive handgrip clamp and extend out, the moving arm (2A) for drive needle mobile device working position, It is moved between reagent disc, sample load units and detection cup.
4. the automatic clinical chemistry analyzer according to claim 1 with allocation unit, which is characterized in that outside the needle Cleaning device includes cleaning agent spout (7-9) and pure water spout (7-8), and two spouts are directed to the tip of middle empty needle, and pure Water purification spout (7-8) is higher than the position cleaning agent spout (7-9), and when use first passes through cleaning agent cleaning head (7-9) to hollow needle point Then outside jet cleaner sprays pure water by pure water spout (7-8) to hollow needle point outside；Cleaning agent after flushing It is fallen into pure water in the waste collection slot of lower section.
5. the automatic clinical chemistry analyzer according to claim 1 with allocation unit, which is characterized in that outside the needle Cleaning device includes pure water spout (7-8), the tip of empty needle during spout is directed toward, by spraying pure water to hollow needle point outside It cleans outside needle point；Pure water after flushing is fallen into the waste collection slot of lower section.
6. the automatic clinical chemistry analyzer according to claim 1 with allocation unit, which is characterized in that the distribution is single Member further includes the outer water sweeper (7-10) of needle, between needle cleaning position and working position, for the needle appearance ponding after cleaning Cleaning.
7. the automatic clinical chemistry analyzer according to claim 1 with allocation unit, which is characterized in that the instrument includes One allocation unit, the allocation unit is simultaneously for distributing reagent and sample.
8. the automatic clinical chemistry analyzer according to claim 1 or claim 7 with allocation unit, which is characterized in that described complete Automatic biochemistry analyzer further includes sample needle, for shifting in sample load units in sample to detection cup.
9. automatic clinical chemistry analyzer according to claim 1, which is characterized in that the instrument includes two allocation units, For one of allocation unit for distributing reagent and sample, another allocation unit is only used for distribution reagent.
CN201710034197.4A 2017-01-17 2017-01-17 Automatic clinical chemistry analyzer with allocation unit Active CN106771293B (en)

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