CN106771293A - Automatic clinical chemistry analyzer with allocation unit - Google Patents

Automatic clinical chemistry analyzer with allocation unit Download PDF

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Publication number
CN106771293A
CN106771293A CN201710034197.4A CN201710034197A CN106771293A CN 106771293 A CN106771293 A CN 106771293A CN 201710034197 A CN201710034197 A CN 201710034197A CN 106771293 A CN106771293 A CN 106771293A
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China
Prior art keywords
pin
hollow needle
cleaning
reagent
sample
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Granted
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CN201710034197.4A
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Chinese (zh)
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CN106771293B (en
Inventor
徐新
宋成桥
张陆军
缪建
潘有铭
纪本奎
郭敏
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Sinnowa Medical Science & Technology Co.,Ltd.
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Jiangsu Ke Lundi Medical Technology Co Ltd
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/026—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0401—Sample carriers, cuvettes or reaction vessels
    • G01N2035/0437—Cleaning cuvettes or reaction vessels

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The invention discloses a kind of automatic clinical chemistry analyzer with allocation unit, the instrument includes reagent disc, reaction tray, agitating unit, sample load units, more than one allocation unit, detection cup cleaning unit, optical detection unit and control and Data Analysis Services unit, allocation unit includes more than one hollow needle, pipeline converter, pin interior cleaning apparatus, pin exterior washings device, waste collection groove and a pin mobile device, for drawing distribution reagent and sample, or be individually used for drawing distribution reagent, or individually draw distribution sample.Automatic clinical chemistry analyzer of the invention, solves traditional automatic clinical chemistry analyzer due to the not thorough caused difference reagents of reagent pin, sample pin internal washing, sample room cross-contamination issue, improves the accuracy and reliability of Instrumental results.

Description

Automatic clinical chemistry analyzer with allocation unit
Technical field
The invention belongs to medical test detection technique field, particularly a kind of full-automatic biochemical analysis with allocation unit Instrument.
Background technology
Automatic clinical chemistry analyzer is the conventional testing equipment of medical institutions.Subject matter in existing this quasi-instrument use One of be exactly that, due to usually needing to use various different reagents, detecting different samples in detecting, and instrument is using shared examination Agent pin and sample pin are measured in drawing different reagents and each detection cup of different samples addition respectively, are drawing reagent and sample When, inside and outside, especially usually remaining reagent and the sample inside pin of reagent pin and sample pin, and thoroughly cleaning is difficult to, in addition Medical laboratory instrument requires and run according to speed higher, therefore, often without time enough to reagent pin and sample pin It is inside and outside to carry out thoroughly cleaning, and cause the reagent or sample of residual to form interference to subsequent detection.And adopted in instrument operation Although can effectively lower or avoid this kind of cross pollution with the mode being cleaned multiple times, so directly result in instrument detection Speed is substantially reduced.
Also there is the method that sample or reagent are drawn using disposable tip in the prior art, but due to drawing examination every time Agent, sample are required for abandoning a used tip, and this is accomplished by larger space and deposits substantial amounts of disposable tip just now May insure that instrument is on duty without operating personnel, and required consumable quantity is very huge during the instrument operation of the design.
The content of the invention
It is an object of the invention to provide a kind of automatic clinical chemistry analyzer with allocation unit, solve existing full-automatic The cross-contamination issue of biochemical analyzer reagent pin and sample pin.
The technical scheme for realizing the object of the invention is：A kind of automatic clinical chemistry analyzer with allocation unit, its feature It is that the instrument includes reagent disc, reaction tray, agitating unit, sample load units, more than one allocation unit, detection cup Cleaning unit, optical detection unit and control and Data Analysis Services unit；
The reagent disc is used to place reagent, and the sample load units are used to place sample, and the reaction tray is used to put Put detection cup；
The allocation unit be used for draw and distribute reagent or sample, including more than one hollow needle, pipeline converter, Pin mobile device and waste collection groove；The pipeline converter includes a working position and more than one cleaning position, working position Be respectively provided with a hollow needle on each cleaning position, each hollow needle is in working position and cleaning interdigit switching；The working position For to reagent or sample is added in the hollow needle on reagent position, the cleaning position to be provided with outside pin interior cleaning apparatus and pin Cleaning device, for being cleaned to hollow needle on cleaning position is inside and outside；The pin mobile device is used to drive reagent position On hollow needle moved between working position and reagent disc, sample disc, detection cup；The waste collection groove is arranged on pipeline and turns Parallel operation lower section, for collecting waste liquid；
The optical detection unit is used to detect liquid in detection cup that the detection cup cleaning unit to be used to clean Detection cup；
The control and Data Analysis Services unit are used to control analyzer each unit cooperating, and to optical detection list First detection data is analyzed treatment.
Compared with prior art, remarkable result of the invention is：
Automatic clinical chemistry analyzer of the present invention with allocation unit can not extend scavenging period, ensure that instrument works On the premise of speed, the residual of reagent inside and outside the pin for drawing reagent and pipette samples and sample is realized fully and effective clear Wash, substantially reduce or even eliminate other cross pollutions formed in the link with quasi-instrument, and it is dirty to intersect in various degree Dye treatment provides the solution of multiple modes, therefore with preferable convenience, feasibility, economy and validity.
Brief description of the drawings
Fig. 1 is a kind of structural representation of automatic clinical chemistry analyzer with allocation unit of the invention, sample in figure Load units are circular sample disk.
Fig. 2 is a kind of structural representation of automatic clinical chemistry analyzer with allocation unit of the invention, sample in figure Load units are rail mounted specimen holder.
Fig. 3-1 is pipeline converter schematic top plan view.
Fig. 3-2 is pipeline converter schematic cross-sectional view.
Fig. 3-3 is pipeline converter working position structural representation.
Fig. 3-4 is the first cleaning position of pipeline converter structural representation.
Fig. 3-5 is the second cleaning position of pipeline converter structural representation.
Fig. 3-6 is the cleaning position structural representation of pipeline converter the 3rd.
Fig. 3-7 is the schematic top plan view of the waste collection groove of allocation unit.
Fig. 4-1~Fig. 4-3 for allocation unit pin mobile device from working position take out hollow needle process schematic, Fig. 4- 4~Fig. 4-6 is put back to the process schematic of working position by hollow needle for the pin mobile device of allocation unit.
Fig. 5 is a kind of structural representation of embodiment of allocation unit of the present invention.
Specific embodiment mode
With reference to Fig. 1, Fig. 2, a kind of automatic clinical chemistry analyzer with allocation unit of the invention, the instrument includes reagent Disk 1, reaction tray 5, agitating unit, sample load units, more than one allocation unit, detection cup cleaning unit 2B, optics inspection Survey unit and control and Data Analysis Services unit；
The reagent disc 1 is used to place reagent, and the sample load units are used to place sample, and the reaction tray 5 is used for Place detection cup 6；
The allocation unit is used to draw and distribute reagent or sample, including the conversion of more than one hollow needle 7-6, pipeline Device 4, pin mobile device and waste collection groove 7-4；The pipeline converter 4 includes a working position and more than one cleaning A hollow needle 7-6 is respectively provided with position, working position and each cleaning position, each hollow needle 7-6 is in working position and cleaning interdigit Switching；The working position is used to add reagent or sample in the hollow needle 7-6 on reagent position, and the cleaning position is provided with pin Portion's cleaning device and pin exterior washings device, for being cleaned to hollow needle 7-6 is inside and outside on cleaning position；The pin is moved Dynamic device is used to drive the hollow needle 7-6 on reagent position between working position and reagent disc 1, sample load units, detection cup 6 It is mobile；The waste collection groove 7-4 is arranged on the lower section of pipeline converter 4, for collecting waste liquid；
The optical detection unit is used to detect liquid in detection cup 6 that the detection cup cleaning unit to be used for clear Wash detection cup；
The control and Data Analysis Services unit are used to control analyzer each unit cooperating, and to optical detection list First detection data is analyzed treatment.
Further, the pipeline converter 4 of the allocation unit includes that runner 7-1, fixed block 7-2 and pipeline converter drive Dynamic motor 7-3；The runner 7-1 is arranged on fixed block 7-2, is close to fixed block 7-2, the pipeline converter motor The rotating shaft of 7-3 is connected through fixed block centre bore with runner 7-1, drives runner 7-1 to rotate；The runner 7-1 and fixed block 7-2 Correspondence position is provided with no less than two passages；When runner 7-1 rotates stopping every time, each passage and fixed block 7-2 on runner Each respective channel is communicated, and not corresponding interchannel is not connected；Port number, the port number of fixed block 7-2 on runner 7-1 with should Hollow needle quantity is identical on allocation unit device, and the passage top on the runner 7-1 is connected by pipeline 7-5 with hollow needle, On the fixed block 7-2 each passage lower section by pipeline respectively with a fixed-quantity injector SAWith more than one cleaning injection Device is connected；
When hollow needle 7-6 is in working position, fixed-quantity injector SABy fixed block passage, runner passage with it is corresponding in Empty needle is communicated；When hollow needle 7-6 is in cleaning position, cleaning syringe is to corresponding fixed block passage, runner passage and hollow needle Injection cleaning agent, water, physiological saline or air, clean to hollow needle.
Further, the fixed-quantity injector SAInterface connected with hollow needle by the passage on fixed block passage and runner It is logical, while being connected with cup by another pipeline, the first valve V is provided with the pipeline being connected with cup1A, with fixed block- The second valve V is provided with the pipeline of runner-hollow needle passage connection2A, close the first valve V1A, while opening the second valve V2A, fixed-quantity injector can quantify extract and discharge reagent or sample；Close the second valve V2A, while opening the first valve V1A, it is fixed Amount syringe extracts the water in cup, and the first valve V is closed afterwards1A, while opening the second valve V2A, pushed away on fixed-quantity injector, Water is expelled in waste collection groove by pipeline through hollow needle.
Further, the pin mobile device includes that transfer arm 2A, handgrip 2-1, the first motor 2M1 and second drive Motor 2M2, the handgrip 2-1 are arranged on transfer arm 2A front ends, and the first motor 2M1 is used to drive handgrip relative to transfer arm Movable, the second motor 2M2 is used to drive handgrip to clamp and extend out, and the transfer arm 2A is used to drive pin mobile device Moved between working position, reagent disc and detection cup.
Further, the pin exterior washings device includes cleaning agent spout 7-9 and pure water spout 7-8, two spouts The tip of hollow needle is directed to, and pure water spout 7-8 is higher than cleaning agent spout 7-9 positions, cleaning agent is first passed through when using clear Hair washing 7-9 is then pure to the injection of hollow needle point outside by pure water spout 7-8 to jet cleaner on the outside of hollow needle point Water；Cleaning agent and pure water after flushing are fallen into the waste collection groove of lower section.
Further, the pin exterior washings device includes pure water spout 7-8, and spout points to the tip of hollow needle, leads to Cross to outside hollow needle point outside injection pure water cleaning needle point；Pure water after flushing is fallen into the waste collection groove of lower section.
Further, the allocation unit also includes the outer water sweeper 7-10 of pin, between pin cleaning position and working position, For to the pin appearance ponding cleaning after cleaning.
Further, the instrument includes an allocation unit, and the allocation unit is used to distribute reagent and sample simultaneously.
Further, the automatic clinical chemistry analyzer also includes sample pin, for shifting sample in sample load units Into detection cup.
Further, the instrument includes two allocation units, and one of allocation unit is used to distribute reagent and sample, separately One allocation unit is only used for distributing reagent.
The present invention is described further with reference to the accompanying drawings and examples.
Embodiment 1
Fig. 1 is one embodiment of automatic clinical chemistry analyzer of the present invention with allocation unit.
The primary structure of the instrument includes two reagent discs 1, reaction tray 5, sample load units, optical detection unit, inspections Cup cleaning unit 2B, 2 allocation units and a sample pin 2C are surveyed, sample load units use circular sample disk 3；Two distribution Unit is used to draw and distribute reagent, and sample pin 2C is used to draw sample；Cleaning position 2D is provided with by sample pin 2C, for cleaning Sample pin 2C.
Wherein, multiple reagent bottle 1-1 are provided with reagent disc 1, reaction tray 5 is provided with multiple detection cups 6, optical detection list Unit includes light source 5A, monochromator 5B and optical signal detector 5C；
Allocation unit includes pin transfer arm 2A/2A ', pipeline converter and waste collection groove, and pipeline converter includes runner 7-1, fixed block 7-2 and pipeline converter motor 7-3；Runner 7-1 is arranged on fixed block 7-2, tight with fixed block 7-2 Patch, the rotating shaft of the pipeline converter motor 7-3 is connected through fixed block centre bore with runner 7-1, drives runner 7-1 to turn It is dynamic；
One allocation unit is set near the first reagent disc R1 positions, the pipeline converter 4 of the allocation unit includes work Position, the first cleaning position, the second cleaning position and the 3rd cleaning position, each working position and cleaning position set a pin position, correspond to respectively Working position pin position A1, the first cleaning position pin position B1, the second cleaning position pin position C1 and the 3rd cleaning position pin position D1, each pin position is run through Hollow needle stand 7-7 is provided with runner 7-1, and each pin position, a hollow needle 7-6 is placed on each hollow needle stand 7-7；
As shown in Fig. 3-1- Fig. 3-6, each pin position is other to be provided with pipe-line system, including first turn on runner 7-1 Wheel passage A2, the second runner passage B2, the 3rd runner channel C 2, the 4th runner passage D2 and positioned at fixed block 7-2 on and with turn The first corresponding fixed block passage A of wheel 7-1 upper channels position, the second fixed block passage B, the 3rd fixed block channel C, the 4th consolidate Determine block passage D；And A1-A2, B1-B2, C1-C2, D1-D2 are to that should have pipeline to be connected.
Top runner 7-1 can be then driven to rotate when motor 7-3 is rotated, the pin being fixed on runner 7-1 also changes position, Simultaneously because fixed block 7-2 does not rotate, therefore when runner 7-1 is rotated every time, on the upper four pins positions of runner 7-1 and fixed block Each passage all synchronously change, it is ensured that the pin of A1 is used to draw reagent or sample all the time, and other three positions Pin is then in cleaning state.Then changed to the first cleaning position by pipeline converter after hollow needle is in the A1 uses of working position pin position Pin position B1 starts cleaning, corresponding former in the first cleaning position pin position B1, the second cleaning position pin position C1 and the 3rd cleaning position pin position D1 Hollow needle is suitable in same direction to move one, in the first cleaning position pin position B1, the second cleaning position pin position C1 and the 3rd cleaning position pin position D1 is once cleaned to hollow needle respectively, is eventually transferred into the hollow needle of working position pin position A1 by clear inside and outside such process Wash.
Fig. 3-3 is pipeline converter working position structural representation, wherein the first valve V1AIt is fixed-quantity injector SAConnecting tube Lead to the pipeline valve of water on road；Second valve V2AIt is fixed-quantity injector SAPipeline is connected to the valve on hollow needle path.Fig. 3-4 It is the first cleaning position of pipeline converter structural representation, wherein the 3rd valve V1BIt is the first cleaning syringe SBLead on connecting line To cleaning agent or the pipeline valve of water or physiological saline or air；4th valve V2BFor syringe pipeline connects hollow needle path On valve.The second cleaning position of Fig. 3-5 pipelines converter structural representation, wherein the 5th valve V1CIt is the second cleaning syringe SC Lead on connecting line or cleaning agent or water or physiological saline or air pipeline valve；6th valve V2CIt is syringe pipeline Valve on connection hollow needle path.The cleaning position structural representation of Fig. 3-6 pipelines converter the 3rd, wherein the 7th valve V1DIt is Three cleaning syringe SDLead on connecting line or cleaning agent or water or physiological saline or air pipeline valve；8th valve V2D It is the valve on syringe pipeline connection hollow needle path.
As shown in figure 3-2, pipeline converter bottom is provided with waste collection groove 7-4, fixed-quantity injector SAFor drawing simultaneously Distribution reagent, the first cleaning syringe SBCleaning agent, water or air are irrigated during for cleaning needle.Such as Fig. 3-3, fixed-quantity injector SA Operation principle is：During the hollow needle of working position pin position A1 enters reagent bottle under the driving of pin mobile device, the first valve is closed V1A, open the second valve V2A, fixed-quantity injector SAPiston pumpback, in reagent suction pin；Moved down when pin drives in pin mobile device Move to detection cup position, fixed-quantity injector SAPiston above push away, then in pin reagent injection detection cup in.Fixed-quantity injector SAIn instrument Certain link in the preproduction phase of device unlatching or work, opens the first valve V1A, close the second valve V2A, fixed-quantity injector SAIt is living Get back into and take out, water is sucked in syringe；It is then turned off the first valve V1A, open the second valve V2A, pushed away on syringe piston so that Syringe and pipeline A-A2-A1 are filled with water.Such as Fig. 3-4, the first cleaning syringe SBDuring work, the 4th valve V is closed2B, open Open the 3rd valve V1B, syringe piston pumpback, cleaning agent or water enter the first cleaning syringe SBIt is interior；Later on 4th valve V2B, close the 3rd valve V1B, the first cleaning syringe SBLiquid enters pipeline B-B2-B1 during then syringe is pushed away on piston, realizes The hollow needle cleaning of the first cleaning position pin position B1.
Another allocation unit, the pipeline conversion of the allocation unit are set near the second reagent disc R2 positions in the instrument Device only has 2 pin positions, i.e. working position pin position A1 and cleaning position pin position B1, and the two pins position is all the time in turn by one of hollow needle During for working, another hollow needle is then in cleaning state.
Each detection cup in reaction tray 5 receives the first reagent at the first detection cup position RC1 all the time, in the second detection cup position Receive sample at RC2, first time stirring is carried out at the 3rd detection cup position RC3, part double reagent detection project is in the 4th detection Receive the second reagent at cup position RC4, carry out second stirring at the 5th detection cup position RC5 afterwards.Reacted when instrument runs Disk 5 every time turn around and stop after+1 by rotation, therefore detection cup position often rotates once just reach one, just in reaction tray rotary course According to order detect cup in add reagent 1, sample, be stirred afterwards, selectively add or be added without reagent 2.Adding After entering reagent 2, agitating device is again stirring for liquid in detection cup, and all detection cup is detected when reaction tray rotates every time, Each detection cup is obtained before and after reagent 1 is added, is added after serum, the absorbance of liquid in cup is detected after addition reagent 2, Finally according to the absorbance data that each detection cup is obtained to overall process detection, analysis obtains the biochemical inspection of projects in different samples Survey result.
Embodiment 2
If Fig. 2, the present embodiment are that the sample load units of the embodiment are track style with the difference of embodiment 1 Product frame 8, and with two allocation units, have an allocation unit, the pipeline of the allocation unit near the first reagent disc R1 positions Converter has three pin positions；There are an allocation unit, the pipeline converter of the allocation unit near the second reagent disc R2 positions With two pin positions.
Embodiment 3
As shown in Figure 3-4, in the present embodiment, the cleaning in the allocation unit to pin is not limited only to inside pin, is also included Cleaning outside pin, pin exterior washings device includes cleaning agent spout 7-9 and pure water spout 7-8, during two spouts are directed to The tip of empty needle, and pure water spout 7-8 be higher than cleaning agent spout 7-9 positions, first passed through when using cleaning agent cleaning head 7-9 to Jet cleaner on the outside of hollow needle point, then by pure water spout 7-8 to hollow needle point outside injection pure water；After flushing Cleaning agent and pure water are fallen into the waste collection groove of lower section.
Or, pure water spout 7-8 is only set outside hollow needle, as in Figure 3-5.
Embodiment 4
Such as Fig. 3-6 and Fig. 3-7, in the present embodiment, four pin positions of pipeline converter lower section corresponds to waste collection groove respectively Four positions of 7-4, respectively the first waste collection groove position A3~the 4th waste collection groove position D3, in the 4th waste collection groove position The outer water sweeper 7-10 of a pair of pins are provided between D3 and the first waste collection groove position A3, hollow needle 7-6 by herein when, outside pin Water sweeper 7-10 removes the ponding hung with hollow needle outer wall automatically.
Waste collection groove 7-4 is provided with waste liquid port 7-11, and all waste liquids are discharged by a waste liquid port 7-11.
Embodiment 5
As shown in Fig. 4-1~Fig. 4-6 and Fig. 1, embodiment provides a kind of specific pin mobile device structure and its work Principle.
Pin mobile device includes transfer arm 2A, handgrip 2-1, the first motor 2M1 and the second motor 2M2, described Handgrip 2-1 is arranged on transfer arm 2A front ends, and the first motor 2M1 is used to drive handgrip movable relative to transfer arm, the Two motor 2M2 are used to drive handgrip to clamp and extend out, and the transfer arm 2A is used to drive pin mobile device in working position, examination Moved between agent disk and detection cup.
During crawl hollow needle, as shown in Fig. 4-1~Fig. 4-3, the second motor 2M2 drives handgrip 2-1 to clamp hollow needle, The first motor 2M1 drives handgrip that hollow needle is removed from needle stand simultaneously, and transfer arm 2A drives handgrip 2-1 afterwards, by Empty needle is moved in reagent disc 1 from working position and draws reagent in reagent bottle 1-1.
When putting back to hollow needle, as shown in Fig. 4-4~Fig. 4-6, transfer arm 2A drives handgrip 2-1 that hollow needle is moved into detection The top of cup 6, the reagent of absorption is distributed into detection cup 6, and transfer arm 2A is moved to working position, the first motor 2M1 afterwards Drive handgrip that hollow needle is placed in into needle stand position, while the second motor 2M2 drives handgrip 2-1 to extend out.
Embodiment 6
As shown in figure 5, in this embodiment, reagent and sample are distributed using same hollow needle.
The pin mobile device of the present embodiment also includes transfer arm base 2L, the 3rd motor 2G, the 4th motor 2F With axostylus axostyle 2K, the 3rd motor 2G and the 4th motor 2F is arranged in transfer arm base 2L, the axostylus axostyle 2K's One end is connected with transfer arm 2A, and the other end is connected with the 3rd motor 2G and the 4th motor 2F respectively, and the 3rd drives electricity Machine 2G is used to control transfer arm to rotate, and the 4th motor 2F is used to control transfer arm to move up and down.
Handgrip 2-1 in pin mobile device removes hollow needle 7-6 from the working position of pipeline converter 4, transfer arm 2A bands Hollow needle 7-6 is transferred to reagent position by dynamic handgrip 2-1, closes the first valve V1A, open the second valve V2A, fixed-quantity injector SAIt is living Get back into and take out, reagent is drawn into hollow needle 7-6；Transfer arm 2A drives handgrip 2-1 that hollow needle 7-6 is moved into detection cup position, Fixed-quantity injector SAPushed away on piston, reagent is distributed into detection cup, realize that reagent is distributed, the handgrip of transfer arm 2A drives afterwards will Hollow needle is transferred to working position.
Close the second valve V2A, open the first valve V1A, fixed-quantity injector SAPiston pumpback, fixed-quantity injector is sucked by water SAIt is interior；Close the first valve V1A, open the second valve V2A, fixed-quantity injector SAPushed away on piston, water enters hollow needle 7- along pipeline 6, hollow needle inside is cleaned；Pipeline converter 4 rotates and for hollow needle to be placed in cleaning position simultaneously, and the outer washer of pin is to hollow Cleaned outside pin.After cleaning, handgrip 2-1 in pin mobile device is by cleaned hollow needle 7-6 from pipeline converter 4 Removed on working position, transfer arm 2A drives handgrip that hollow needle is transferred into sample position, closes the first valve V1A, open the second valve V2A, fixed-quantity injector SAPiston pumpback, sample is drawn into hollow needle 7-6；Transfer arm 2A drives handgrip 2-1 by hollow needle 7- 6 are moved to detection cup position, fixed-quantity injector SAPushed away on piston, sample is distributed into detection cup, realize that sample is distributed.Manage afterwards Road converter 4 rotates and for pin to be placed in cleaning position, and the outer washer of pin outside pin to cleaning.
Embodiment 7
The present embodiment is that pin mobile device drives hollow needle 7-6 individually in sample position and detection with the difference of embodiment 6 Moved between cup, realize that sample is distributed.
Embodiment 8
The present embodiment is that pin mobile device drives hollow needle 7-6 individually in reagent position and detection with the difference of embodiment 6 Moved between cup, realize that reagent is distributed.
The invention provides a kind of automatic clinical chemistry analyzer with allocation unit, the above is only of the invention excellent Select implementation method, it is noted that for those skilled in the art, do not depart from the premise of the principle of the invention Under, some improvements and modifications can also be made, these improvements and modifications also should be regarded as protection scope of the present invention.In the present embodiment Each part not yet explicitly can use prior art to be realized.

Claims (10)

1. a kind of automatic clinical chemistry analyzer with allocation unit, it is characterised in that the instrument includes reagent disc (1), reaction Disk (5), agitating unit, sample load units, more than one allocation unit, detection cup cleaning unit (2B), optical detection list Unit and control and Data Analysis Services unit；
The reagent disc (1) is used to place sample for placing reagent, the sample load units, and the reaction tray (5) is used for Place detection cup (6)；
The allocation unit is used to draw and distribute reagent or sample, including more than one hollow needle (7-6), pipeline converter (4), pin mobile device and waste collection groove (7-4)；The pipeline converter (4) includes a working position and more than one clear Position is washed, a hollow needle (7-6) is respectively provided with working position and each cleaning position, each hollow needle (7-6) is in working position and clearly Wash interdigit switching；The working position is used to add reagent or sample in the hollow needle (7-6) on reagent position, and the cleaning position sets Pin interior cleaning apparatus and pin exterior washings device are equipped with, for being carried out clearly to hollow needle on cleaning position (7-6) is inside and outside Wash；The pin mobile device is used to drive the hollow needle (7-6) on reagent position to be loaded in working position and reagent disc (1), sample Moved between unit, detection cup (6)；The waste collection groove (7-4) is arranged on pipeline converter (4) lower section, useless for collecting Liquid；
The optical detection unit is used to detect liquid in detection cup (6) that the detection cup cleaning unit to be used to clean Detection cup；
The control and Data Analysis Services unit are used to control analyzer each unit cooperating, and optical detection unit is examined Survey data and be analyzed treatment.
2. the automatic clinical chemistry analyzer with allocation unit according to claim 1, it is characterised in that the distribution list The pipeline converter (4) of unit includes runner (7-1), fixed block (7-2) and pipeline converter motor (7-3)；The runner (7-1) is arranged on fixed block (7-2), is close to fixed block (7-2), the rotating shaft of the pipeline converter motor (7-3) It is connected with runner (7-1) through fixed block centre bore, drives runner (7-1) to rotate；The runner (7-1) and fixed block (7-2) Correspondence position is provided with no less than two passages；Runner (7-1) is rotated when stopping every time, each passage and fixed block on runner (7-2) each respective channel is communicated, and not corresponding interchannel is not connected；Port number, fixed block (7-2) on runner (7-1) Port number is identical with hollow needle quantity on the allocation unit device, and the passage top on the runner (7-1) passes through pipeline (7-5) Be connected with hollow needle, each passage on the fixed block (7-2) lower section by pipeline respectively with a fixed-quantity injector (SA) and More than one cleaning syringe connection.
When hollow needle (7-6) is in working position, fixed-quantity injector (SA) by fixed block passage, runner passage with it is corresponding in Empty needle is communicated；When hollow needle (7-6) is in cleaning position, cleaning syringe is to corresponding fixed block passage, runner passage and hollow Pin injection cleaning agent, water, physiological saline or air, clean to hollow needle.
3. the automatic clinical chemistry analyzer with allocation unit according to claim 2, it is characterised in that the quantitative note Emitter (SA) interface connected with hollow needle by the passage on fixed block passage and runner, while by another pipeline and cup Connection, is provided with the first valve (V on the pipeline being connected with cup1A), the pipe being connected with fixed block-runner-hollow needle passage The second valve (V is provided with road2A), close the first valve (V1A), while opening the second valve (V2A), fixed-quantity injector can be determined Amount is extracted and discharge reagent or sample；Close the second valve (V2A), while opening the first valve (V1A), fixed-quantity injector is extracted Water in cup, closes the first valve (V afterwards1A), while opening the second valve (V2A), being pushed away on fixed-quantity injector, water is by pipe Road is expelled in waste collection groove through hollow needle.
4. the automatic clinical chemistry analyzer with allocation unit according to claim 1 and 2, it is characterised in that the pin Mobile device includes transfer arm (2A), handgrip (2-1), the first motor (2M1) and the second motor (2M2), described to grab Hand (2-1) is arranged on transfer arm (2A) front end, and the first motor (2M1) is used to drive handgrip to be moved relative to before and after transfer arm Dynamic, the second motor (2M2) is used to drive handgrip to clamp and extend out, and the transfer arm (2A) is used to drive pin mobile device to exist Moved between working position, reagent disc, sample load units and detection cup.
5. the automatic clinical chemistry analyzer with allocation unit according to claim 1 and 2, it is characterised in that the pin Exterior washings device includes cleaning agent spout (7-9) and pure water spout (7-8), and two spouts are directed to the tip of hollow needle, And pure water spout (7-8) is higher than cleaning agent spout (7-9) position, and cleaning agent cleaning head (7-9) is first passed through when using to hollow Jet cleaner on the outside of needle point, then by pure water spout (7-8) to hollow needle point outside injection pure water；It is clear after flushing Lotion and pure water are fallen into the waste collection groove of lower section.
6. the automatic clinical chemistry analyzer with allocation unit according to claim 1, it is characterised in that outside the pin Cleaning device includes pure water spout (7-8), and spout points to the tip of hollow needle, by hollow needle point outside injection pure water Outside cleaning needle point；Pure water after flushing is fallen into the waste collection groove of lower section.
7. the automatic clinical chemistry analyzer with allocation unit according to claim 1, it is characterised in that the distribution list Unit also includes outer water sweeper (7-10) of pin, between pin cleaning position and working position, for the pin appearance ponding after cleaning Cleaning.
8. the automatic clinical chemistry analyzer with allocation unit according to claim 1, it is characterised in that the instrument includes One allocation unit, the allocation unit is used to distribute reagent and sample simultaneously.
9. the automatic clinical chemistry analyzer with allocation unit according to claim 1 or 8, it is characterised in that described complete Automatic biochemistry analyzer also includes sample pin, for shifting in sample load units sample into detecting cup.
10. automatic clinical chemistry analyzer according to claim 1, it is characterised in that the instrument includes two allocation units, One of allocation unit is used to distribute reagent and sample, and another allocation unit is only used for distributing reagent.
CN201710034197.4A 2017-01-17 2017-01-17 Automatic clinical chemistry analyzer with allocation unit Active CN106771293B (en)

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