CN102816194A - 大环化合物以及其制作和使用方法 - Google Patents

大环化合物以及其制作和使用方法 Download PDF

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Publication number
CN102816194A
CN102816194A CN2012102533942A CN201210253394A CN102816194A CN 102816194 A CN102816194 A CN 102816194A CN 2012102533942 A CN2012102533942 A CN 2012102533942A CN 201210253394 A CN201210253394 A CN 201210253394A CN 102816194 A CN102816194 A CN 102816194A
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CN
China
Prior art keywords
saturated
unsaturated
membered
mmol
compound
Prior art date
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Pending
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CN2012102533942A
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English (en)
Chinese (zh)
Inventor
杰伊·J·法默
阿肖克·包哈塔查杰
陈毅
乔尔·A·戈德伯格
约瑟夫·A·伊波利托
佐欧坦·F·凯尤
楼荣亮
阿德格博伊加·K·欧耶利尔
爱德华·C·舍瑞尔
乔伊斯·A·萨特克利夫
王德平
吴育生
杜严明
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Melinta Subsidiary Corp
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Rib X Pharmaceuticals Inc
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Filing date
Publication date
Application filed by Rib X Pharmaceuticals Inc filed Critical Rib X Pharmaceuticals Inc
Publication of CN102816194A publication Critical patent/CN102816194A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CN2012102533942A 2004-02-27 2005-02-25 大环化合物以及其制作和使用方法 Pending CN102816194A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US54828004P 2004-02-27 2004-02-27
US60/548,280 2004-02-27
US57594904P 2004-06-01 2004-06-01
US60/575,949 2004-06-01

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN 200580013532 Division CN1950388A (zh) 2004-02-27 2005-02-25 大环化合物以及其制作和使用方法

Publications (1)

Publication Number Publication Date
CN102816194A true CN102816194A (zh) 2012-12-12

Family

ID=34922681

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2012102533942A Pending CN102816194A (zh) 2004-02-27 2005-02-25 大环化合物以及其制作和使用方法

Country Status (5)

Country Link
US (4) US8202843B2 (https=)
EP (2) EP1723159B1 (https=)
JP (5) JP5383037B2 (https=)
CN (1) CN102816194A (https=)
WO (1) WO2005085266A2 (https=)

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JP5631909B2 (ja) 2014-11-26
US8841263B2 (en) 2014-09-23
JP2014208707A (ja) 2014-11-06
JP2007525520A (ja) 2007-09-06
US20080045585A1 (en) 2008-02-21
WO2005085266A8 (en) 2005-12-01
JP5383037B2 (ja) 2014-01-08
WO2005085266A2 (en) 2005-09-15
EP1723159A2 (en) 2006-11-22
EP2716647A3 (en) 2014-08-20
JP2018104437A (ja) 2018-07-05
US20180066007A1 (en) 2018-03-08
JP2017019786A (ja) 2017-01-26
US20150158901A1 (en) 2015-06-11
WO2005085266A3 (en) 2006-01-05
US20120252747A1 (en) 2012-10-04
EP2716647A2 (en) 2014-04-09
EP1723159B1 (en) 2019-06-12
JP2012102147A (ja) 2012-05-31
US8202843B2 (en) 2012-06-19

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