TW355711B - Erythromycin derivatives - Google Patents

Erythromycin derivatives

Info

Publication number
TW355711B
TW355711B TW082109245A TW82109245A TW355711B TW 355711 B TW355711 B TW 355711B TW 082109245 A TW082109245 A TW 082109245A TW 82109245 A TW82109245 A TW 82109245A TW 355711 B TW355711 B TW 355711B
Authority
TW
Taiwan
Prior art keywords
hydrogen
erythromycin derivatives
alkyl
hydroxy
erythromycin
Prior art date
Application number
TW082109245A
Other languages
Chinese (zh)
Inventor
Hiroshi Koga
Kouichi Tsuzuki
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of TW355711B publication Critical patent/TW355711B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Abstract

A compound of formula (I) or salts thereof: wherein R is hydrogen, R2 is hydroxy, R3 is hydrogen, R4 is hydrogen or benzyl, R5 is C1-C5 alkyl, Y is -NR6R7 or -N+R8R9R10X-, in which R6, R8 and R9 are hydrogen or C1-C6 alkyl, R7 is C2-C6 alkenyl, C5-C7 cycloalkyl, C1-C6 alkyl substitutable by hydroxy or amino, R10 is C2-C6 alkynyl, X is an anion.
TW082109245A 1992-11-04 1993-11-03 Erythromycin derivatives TW355711B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP29519692 1992-11-04

Publications (1)

Publication Number Publication Date
TW355711B true TW355711B (en) 1999-04-11

Family

ID=17817444

Family Applications (1)

Application Number Title Priority Date Filing Date
TW082109245A TW355711B (en) 1992-11-04 1993-11-03 Erythromycin derivatives

Country Status (4)

Country Link
CN (1) CN1091431A (en)
AU (1) AU5376394A (en)
TW (1) TW355711B (en)
WO (1) WO1994010185A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6077943A (en) * 1996-03-01 2000-06-20 Takeda Chemical Industries, Ltd. Method of producing erythromycin derivative
DE60206921T2 (en) * 2001-06-13 2006-07-20 Ube Industries, Ltd., Ube METHOD FOR PRODUCING ERYTHROMYCIN COMPOUNDS
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
EP1723159B1 (en) 2004-02-27 2019-06-12 Melinta Therapeutics, Inc. Macrocyclic compounds and methods of making and using the same
GB0611907D0 (en) 2006-06-15 2006-07-26 Glaxo Group Ltd Compounds
EP1902022A1 (en) 2005-07-12 2008-03-26 Glaxo Group Limited Piperazine heteroaryl derivates as gpr38 agonists
MY150098A (en) 2005-07-26 2013-11-29 Glaxo Group Ltd Benzylpiperazine derivates and their medical use
MX2009000110A (en) 2006-06-28 2009-01-23 Glaxo Group Ltd Piperazinyl derivatives useful in the treatment of gpr38 receptor mediated diseases.
KR101575703B1 (en) 2009-02-27 2015-12-10 라퀄리아 파마 인코포레이티드 Oxyindole derivatives with motilin receptor agonistic activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3689758T2 (en) * 1985-08-31 1994-08-18 Kitasato Inst Erythromycin derivative and process for its preparation.

Also Published As

Publication number Publication date
WO1994010185A1 (en) 1994-05-11
AU5376394A (en) 1994-05-24
CN1091431A (en) 1994-08-31

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