CN102802686A - 骨髓胞外基质提取物及其治疗用途 - Google Patents

骨髓胞外基质提取物及其治疗用途 Download PDF

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Publication number
CN102802686A
CN102802686A CN2010800267188A CN201080026718A CN102802686A CN 102802686 A CN102802686 A CN 102802686A CN 2010800267188 A CN2010800267188 A CN 2010800267188A CN 201080026718 A CN201080026718 A CN 201080026718A CN 102802686 A CN102802686 A CN 102802686A
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China
Prior art keywords
cells
cell
extracellular matrix
bone marrow
hematopoietic
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Pending
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CN2010800267188A
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English (en)
Chinese (zh)
Inventor
M·埃尔-萨班
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MC2 Cell ApS
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MC2 Cell ApS
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Publication of CN102802686A publication Critical patent/CN102802686A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633—Extracellular matrix [ECM]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biophysics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN2010800267188A 2009-06-18 2010-06-18 骨髓胞外基质提取物及其治疗用途 Pending CN102802686A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21818209P 2009-06-18 2009-06-18
US61/218,182 2009-06-18
PCT/EP2010/058675 WO2010146177A1 (en) 2009-06-18 2010-06-18 Bone marrow extracellular matrix extract and therapeutic use thereof

Publications (1)

Publication Number Publication Date
CN102802686A true CN102802686A (zh) 2012-11-28

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010800267188A Pending CN102802686A (zh) 2009-06-18 2010-06-18 骨髓胞外基质提取物及其治疗用途

Country Status (5)

Country Link
US (1) US20120065620A1 (enExample)
EP (1) EP2442837B1 (enExample)
JP (1) JP2012533519A (enExample)
CN (1) CN102802686A (enExample)
WO (1) WO2010146177A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105395570A (zh) * 2015-09-23 2016-03-16 广东颐养抗衰老研究院 一种用于治疗老年性白血病的组合物
CN115531609A (zh) * 2016-02-06 2022-12-30 哈佛学院校长同事会 重塑造血巢以重建免疫

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3095142A1 (en) 2018-03-30 2019-10-03 University Of Rochester Bioengineered wharton's jelly derived extracellular matrix

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005009498A2 (en) * 2003-07-17 2005-02-03 Boston Scientific Limited Decellularized bone marrow extracellular matrix
WO2007056547A2 (en) * 2005-11-08 2007-05-18 Georgia Tech Research Corporation Acellularized biomaterial from embryonic stem cells
CN101062428A (zh) * 2006-04-24 2007-10-31 中国人民解放军军事医学科学院野战输血研究所 一种组织工程化皮肤的构建方法与应用

Family Cites Families (13)

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US5674750A (en) 1995-05-19 1997-10-07 T. Breeders Continuous selective clonogenic expansion of relatively undifferentiated cells
US5925567A (en) 1995-05-19 1999-07-20 T. Breeders, Inc. Selective expansion of target cell populations
IT1282207B1 (it) * 1995-11-20 1998-03-16 Fidia Advanced Biopolymers Srl Sistemi di coltura di cellule staminali di midollo osseo umano in matrici tridimensionali costituiti da esteri dell'acido ialuronico
ES2338405T3 (es) * 1999-02-04 2010-05-07 Pluristem Ltd. Metodo y aparato para mantenimiento y expasion de celulas madre hemopoyeticas y/o celulas progenitoras.
US20040151700A1 (en) * 2001-10-30 2004-08-05 Harlan David M. Ex-vivo rescue of transplantable hematopoietic stem cells following myeloablative injury
AU2004242091C1 (en) * 2003-05-07 2009-12-24 La Jolla Institute For Molecular Medicine Administration of hyaluronic acid to enhance the function of transplanted stem cells
JP2005192521A (ja) * 2004-01-09 2005-07-21 Hiroko Sato 部分分解重合性タンパク質からなる造血幹細胞を含む未熟な血液細胞（ｈｓｃ）の増殖促進用支持体およびその支持体を使用したｈｓｃの製造方法。
CN105168250B (zh) * 2004-10-25 2019-02-05 塞勒兰特治疗公司 增殖骨髓细胞群体的方法及其应用
CN101421393B (zh) * 2006-02-14 2013-08-14 塞勒兰特治疗公司 提高造血干细胞植入的方法和组合物
WO2007148332A1 (en) * 2006-06-22 2007-12-27 Yeda Resaerch And Development Co. Ltd Catecholamine receptor modulation
DE102006060247A1 (de) * 2006-09-15 2008-03-27 Ossacur Ag Differenzierung von Stammzellen
WO2009072990A1 (en) * 2007-12-06 2009-06-11 Agency For Science, Technology And Research Method for extracellular matrix mediated differentiation and proliferation of stem cells
WO2009080794A1 (en) * 2007-12-21 2009-07-02 Mc2 Cell Aps Method for preparing cell-specific extracellular matrices

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005009498A2 (en) * 2003-07-17 2005-02-03 Boston Scientific Limited Decellularized bone marrow extracellular matrix
WO2007056547A2 (en) * 2005-11-08 2007-05-18 Georgia Tech Research Corporation Acellularized biomaterial from embryonic stem cells
CN101062428A (zh) * 2006-04-24 2007-10-31 中国人民解放军军事医学科学院野战输血研究所 一种组织工程化皮肤的构建方法与应用

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105395570A (zh) * 2015-09-23 2016-03-16 广东颐养抗衰老研究院 一种用于治疗老年性白血病的组合物
CN115531609A (zh) * 2016-02-06 2022-12-30 哈佛学院校长同事会 重塑造血巢以重建免疫

Also Published As

Publication number Publication date
EP2442837B1 (en) 2014-08-20
US20120065620A1 (en) 2012-03-15
JP2012533519A (ja) 2012-12-27
WO2010146177A1 (en) 2010-12-23
EP2442837A1 (en) 2012-04-25

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Application publication date: 20121128