JP2012533519A - 骨髄細胞外マトリックス抽出物およびその治療上の使用 - Google Patents

骨髄細胞外マトリックス抽出物およびその治療上の使用 Download PDF

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JP2012533519A
JP2012533519A JP2012515517A JP2012515517A JP2012533519A JP 2012533519 A JP2012533519 A JP 2012533519A JP 2012515517 A JP2012515517 A JP 2012515517A JP 2012515517 A JP2012515517 A JP 2012515517A JP 2012533519 A JP2012533519 A JP 2012533519A
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cells
cell
extracellular matrix
bone marrow
hematopoietic
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JP2012533519A5 (enExample
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エル−サバン、マルワン
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MC2 Cell ApS
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608Bone, e.g. demineralised bone matrix [DBM], bone powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633Extracellular matrix [ECM]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biophysics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2012515517A 2009-06-18 2010-06-18 骨髄細胞外マトリックス抽出物およびその治療上の使用 Pending JP2012533519A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21818209P 2009-06-18 2009-06-18
US61/218,182 2009-06-18
PCT/EP2010/058675 WO2010146177A1 (en) 2009-06-18 2010-06-18 Bone marrow extracellular matrix extract and therapeutic use thereof

Publications (2)

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JP2012533519A true JP2012533519A (ja) 2012-12-27
JP2012533519A5 JP2012533519A5 (enExample) 2013-05-30

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US (1) US20120065620A1 (enExample)
EP (1) EP2442837B1 (enExample)
JP (1) JP2012533519A (enExample)
CN (1) CN102802686A (enExample)
WO (1) WO2010146177A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12472282B2 (en) 2018-03-30 2025-11-18 University Of Rochester Bioengineered wharton's jelly derived extracellular matrix

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105395570A (zh) * 2015-09-23 2016-03-16 广东颐养抗衰老研究院 一种用于治疗老年性白血病的组合物
EP3411475B1 (en) * 2016-02-06 2025-08-27 President and Fellows of Harvard College Recapitulating the hematopoietic niche to reconstitute immunity

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000500372A (ja) * 1995-11-20 2000-01-18 フィディア アドヴァンスド バイオポリマーズ ソシエタ ア レスポンサビリタ リミタータ 結合組織細胞に部分的又は完全に分化した骨髄幹細胞の有効培養物及びヒアルロン酸誘導体より成る三次元の生体親和性で且つ生分解性のマトリックスから構成される生物学的物質
JP2002535981A (ja) * 1999-02-04 2002-10-29 テクニオン リサーチ アンド デブェロップメント ファウンデーション リミテド 造血幹細胞および/または前駆細胞を維持および増加するための方法および装置
WO2005009498A2 (en) * 2003-07-17 2005-02-03 Boston Scientific Limited Decellularized bone marrow extracellular matrix
JP2005192521A (ja) * 2004-01-09 2005-07-21 Hiroko Sato 部分分解重合性タンパク質からなる造血幹細胞を含む未熟な血液細胞(hsc)の増殖促進用支持体およびその支持体を使用したhscの製造方法。
JP2007535486A (ja) * 2003-05-07 2007-12-06 ラ ホーヤ インスティチュート フォー モレキュラー メディシン 高分子量のヒアルロン酸を用いた内因性又は埋め込まれた又は移植された幹細胞の機能回復を促進するための方法
WO2007148332A1 (en) * 2006-06-22 2007-12-27 Yeda Resaerch And Development Co. Ltd Catecholamine receptor modulation

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US5674750A (en) 1995-05-19 1997-10-07 T. Breeders Continuous selective clonogenic expansion of relatively undifferentiated cells
US5925567A (en) 1995-05-19 1999-07-20 T. Breeders, Inc. Selective expansion of target cell populations
US20040151700A1 (en) * 2001-10-30 2004-08-05 Harlan David M. Ex-vivo rescue of transplantable hematopoietic stem cells following myeloablative injury
CN105168250B (zh) * 2004-10-25 2019-02-05 塞勒兰特治疗公司 增殖骨髓细胞群体的方法及其应用
AU2006311482B2 (en) * 2005-11-08 2011-08-25 Georgia Tech Research Corporation Acellularized biomaterial from embryonic stem cells
CN101421393B (zh) * 2006-02-14 2013-08-14 塞勒兰特治疗公司 提高造血干细胞植入的方法和组合物
CN101062428A (zh) * 2006-04-24 2007-10-31 中国人民解放军军事医学科学院野战输血研究所 一种组织工程化皮肤的构建方法与应用
DE102006060247A1 (de) * 2006-09-15 2008-03-27 Ossacur Ag Differenzierung von Stammzellen
WO2009072990A1 (en) * 2007-12-06 2009-06-11 Agency For Science, Technology And Research Method for extracellular matrix mediated differentiation and proliferation of stem cells
WO2009080794A1 (en) * 2007-12-21 2009-07-02 Mc2 Cell Aps Method for preparing cell-specific extracellular matrices

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000500372A (ja) * 1995-11-20 2000-01-18 フィディア アドヴァンスド バイオポリマーズ ソシエタ ア レスポンサビリタ リミタータ 結合組織細胞に部分的又は完全に分化した骨髄幹細胞の有効培養物及びヒアルロン酸誘導体より成る三次元の生体親和性で且つ生分解性のマトリックスから構成される生物学的物質
JP2002535981A (ja) * 1999-02-04 2002-10-29 テクニオン リサーチ アンド デブェロップメント ファウンデーション リミテド 造血幹細胞および/または前駆細胞を維持および増加するための方法および装置
JP2007535486A (ja) * 2003-05-07 2007-12-06 ラ ホーヤ インスティチュート フォー モレキュラー メディシン 高分子量のヒアルロン酸を用いた内因性又は埋め込まれた又は移植された幹細胞の機能回復を促進するための方法
WO2005009498A2 (en) * 2003-07-17 2005-02-03 Boston Scientific Limited Decellularized bone marrow extracellular matrix
JP2005192521A (ja) * 2004-01-09 2005-07-21 Hiroko Sato 部分分解重合性タンパク質からなる造血幹細胞を含む未熟な血液細胞(hsc)の増殖促進用支持体およびその支持体を使用したhscの製造方法。
WO2007148332A1 (en) * 2006-06-22 2007-12-27 Yeda Resaerch And Development Co. Ltd Catecholamine receptor modulation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6014017812; Regen. Med. Vol.2, No.4, 2007, p.383-390 *
JPN6014017813; STEM CELLS Vol.22, No.4, 2004, p.544-555 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12472282B2 (en) 2018-03-30 2025-11-18 University Of Rochester Bioengineered wharton's jelly derived extracellular matrix

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EP2442837B1 (en) 2014-08-20
US20120065620A1 (en) 2012-03-15
CN102802686A (zh) 2012-11-28
WO2010146177A1 (en) 2010-12-23
EP2442837A1 (en) 2012-04-25

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