CN102753972B - 涉及使用磁性颗粒的测定方法和装置 - Google Patents

涉及使用磁性颗粒的测定方法和装置 Download PDF

Info

Publication number
CN102753972B
CN102753972B CN201080057103.1A CN201080057103A CN102753972B CN 102753972 B CN102753972 B CN 102753972B CN 201080057103 A CN201080057103 A CN 201080057103A CN 102753972 B CN102753972 B CN 102753972B
Authority
CN
China
Prior art keywords
magnetic
assay device
sample
assay
capture molecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201080057103.1A
Other languages
English (en)
Chinese (zh)
Other versions
CN102753972A (zh
Inventor
I.门德尔-哈特维希
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
J Remsen International Assets LLC
J&j Jsc
Original Assignee
Amic AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amic AB filed Critical Amic AB
Publication of CN102753972A publication Critical patent/CN102753972A/zh
Application granted granted Critical
Publication of CN102753972B publication Critical patent/CN102753972B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0825—Test strips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/163—Biocompatibility
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
CN201080057103.1A 2009-10-16 2010-10-18 涉及使用磁性颗粒的测定方法和装置 Expired - Fee Related CN102753972B (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US25240009P 2009-10-16 2009-10-16
US61/252,400 2009-10-16
SE0950762-5 2009-10-16
US61/252400 2009-10-16
SE0950762 2009-10-16
PCT/EP2010/065600 WO2011045436A1 (en) 2009-10-16 2010-10-18 An assay method and devices involving the use of magnetic particles

Publications (2)

Publication Number Publication Date
CN102753972A CN102753972A (zh) 2012-10-24
CN102753972B true CN102753972B (zh) 2016-01-13

Family

ID=43334528

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201080057103.1A Expired - Fee Related CN102753972B (zh) 2009-10-16 2010-10-18 涉及使用磁性颗粒的测定方法和装置

Country Status (6)

Country Link
EP (1) EP2488871B1 (enExample)
JP (2) JP2013507633A (enExample)
CN (1) CN102753972B (enExample)
CA (1) CA2777807A1 (enExample)
RU (1) RU2595843C2 (enExample)
WO (1) WO2011045436A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130210036A1 (en) * 2012-01-20 2013-08-15 Ortho-Clinical Diagnostics, Inc. Controlling Fluid Flow Through An Assay Device
CA2882595C (en) * 2012-08-21 2019-06-04 Ortho-Clinical Diagnostics, Inc. Antibodies to olanzapine haptens and use thereof
WO2014031662A2 (en) 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc Antibodies to olanzapine and use thereof
CN105102979B (zh) 2013-01-29 2017-05-03 生物辐射海法有限公司 利用磁性纳米粒子的检测测定法
CN112782393B (zh) * 2013-03-11 2024-11-19 克忧健康公司 用于检测和量化分析物的系统和方法
CN103308671B (zh) * 2013-05-22 2016-02-03 北京康彻思坦生物技术有限公司 一种检测膜及检测系统
CN103323603A (zh) * 2013-06-07 2013-09-25 博奥生物有限公司 一种在磁珠表面共价偶联蛋白质的方法
CN105531578B (zh) * 2013-06-28 2018-06-12 丹麦技术大学 生物传感器及其相关方法
JP6278772B2 (ja) * 2014-03-19 2018-02-14 テルモ株式会社 血糖値測定用チップ
JP6466775B2 (ja) 2015-04-30 2019-02-06 シスメックス株式会社 検体分析カートリッジを用いた検体分析方法、検体分析カートリッジ、および、検体分析装置
WO2016182402A1 (ko) * 2015-05-13 2016-11-17 (주)에스엘에스 복수개의 금속 나노 태그를 이용한 복수개의 타겟의 동시 분석 방법
CN105424922B (zh) * 2015-12-09 2018-01-19 北京乐普医疗科技有限责任公司 基于磁珠包被抗体的微流控芯片及捕获心肌标志物的方法
US11162938B2 (en) 2017-03-28 2021-11-02 Denka Company Limited Membrane carrier, kit for testing liquid sample using same, and manufacturing method thereof
US11561197B2 (en) 2018-06-29 2023-01-24 AMMR Joint Venture Electronic detection of a target based on enzymatic cleavage of a reporter moiety
US20210299656A1 (en) * 2018-08-03 2021-09-30 National Research Council Of Canada Magnetic Nanoparticle Distribution in Microfluidic Chip
GB201818412D0 (en) * 2018-11-12 2018-12-26 Lumiradx Tech Ltd A magnetic assembly for use in a device for conducting assays
CA3157610A1 (en) * 2019-11-15 2021-05-20 Redbud Labs, Inc. Microfluidic device for and methods of using surface-attached posts and capture beads in a microfluidic chamber
WO2023141199A2 (en) * 2022-01-21 2023-07-27 Trustees Of Dartmouth College Microtransfer patterning of magnetic materials for microfluidic applications

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6136549A (en) * 1999-10-15 2000-10-24 Feistel; Christopher C. systems and methods for performing magnetic chromatography assays
WO2001071344A2 (en) * 2000-03-17 2001-09-27 Quantum Design, Inc. Immunochromatographic assay method and apparatus
CN1546520A (zh) * 2003-12-12 2004-11-17 上海交通大学 纳米磁性颗粒分离纯化链酶亲合素的方法
CN1595161A (zh) * 2004-06-22 2005-03-16 北京倍爱康生物技术股份有限公司 一种甲状腺过氧化物酶抗体磁分离酶联免疫检测方法
CN1603823A (zh) * 2003-09-30 2005-04-06 江西中德生物工程有限公司 桔霉素免疫层析检测试纸的制作方法与应用
US20080108151A1 (en) * 2002-01-15 2008-05-08 Binax, Inc. Process for (A) Separating Biological Ligands From Dilute Solutions and (B) Conducting An Immunochromatographic Assay Thereof Employing Superparamagnetic Particles Throughout
CN201087839Y (zh) * 2007-03-30 2008-07-16 万华普曼生物工程有限公司 脑钠肽颜色颗粒诊断试纸
CN101315382A (zh) * 2008-07-18 2008-12-03 中国检验检疫科学研究院 用于检测卡那霉素残留的免疫胶体金试纸条及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6479302B1 (en) * 1997-01-30 2002-11-12 Merck Patent Gesellschaft Mit Method for the immunological determination of an analyte
SE0201738D0 (sv) * 2002-06-07 2002-06-07 Aamic Ab Micro-fluid structures
SE0400662D0 (sv) * 2004-03-24 2004-03-24 Aamic Ab Assay device and method
SE527036C2 (sv) * 2004-06-02 2005-12-13 Aamic Ab Analysanordning med reglerat flöde och motsvarande förfarande
JP4791867B2 (ja) * 2005-03-31 2011-10-12 日立マクセル株式会社 貴金属コート磁性粒子を用いた被検物質の検出方法
WO2006134546A2 (en) 2005-06-17 2006-12-21 Koninklijke Philips Electronics N.V. Accurate magnetic biosensor
SE528233C2 (sv) * 2005-06-20 2006-09-26 Aamic Ab Metod och medel för att åstadkomma vätsketransport
GB2436616A (en) * 2006-03-29 2007-10-03 Inverness Medical Switzerland Assay device and method
WO2007129275A2 (en) 2006-05-10 2007-11-15 Koninklijke Philips Electronics N.V. Rapid magnetic biosensor
WO2007149043A1 (en) * 2006-06-20 2007-12-27 Åmic AB Assay device
SE531948C2 (sv) 2006-06-20 2009-09-15 Aamic Ab Analysanordning för vätskeprover innefattande filter i direkt kontakt med projektioner
US8409877B2 (en) 2006-12-29 2013-04-02 Intel Corporation Enzymatic signal generation and detection of binding complexes in stationary fluidic chip
WO2009009408A2 (en) 2007-07-06 2009-01-15 Applied Biosystems Inc. Devices and methods for the detection of analytes

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6136549A (en) * 1999-10-15 2000-10-24 Feistel; Christopher C. systems and methods for performing magnetic chromatography assays
WO2001071344A2 (en) * 2000-03-17 2001-09-27 Quantum Design, Inc. Immunochromatographic assay method and apparatus
US20080108151A1 (en) * 2002-01-15 2008-05-08 Binax, Inc. Process for (A) Separating Biological Ligands From Dilute Solutions and (B) Conducting An Immunochromatographic Assay Thereof Employing Superparamagnetic Particles Throughout
CN1603823A (zh) * 2003-09-30 2005-04-06 江西中德生物工程有限公司 桔霉素免疫层析检测试纸的制作方法与应用
CN1546520A (zh) * 2003-12-12 2004-11-17 上海交通大学 纳米磁性颗粒分离纯化链酶亲合素的方法
CN1595161A (zh) * 2004-06-22 2005-03-16 北京倍爱康生物技术股份有限公司 一种甲状腺过氧化物酶抗体磁分离酶联免疫检测方法
CN201087839Y (zh) * 2007-03-30 2008-07-16 万华普曼生物工程有限公司 脑钠肽颜色颗粒诊断试纸
CN101315382A (zh) * 2008-07-18 2008-12-03 中国检验检疫科学研究院 用于检测卡那霉素残留的免疫胶体金试纸条及其制备方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Functional Magnetic Particles for Medical Application;Masashige Shinkai;《Journal of Bioscience and Bioengineering》;20021231;第94卷(第6期);606-613 *
基于纳米磁性微球的免疫层析定量检测技术研究;刘辉荣;《基础科学辑》;20081231;A006-8 *

Also Published As

Publication number Publication date
JP2016035465A (ja) 2016-03-17
EP2488871B1 (en) 2017-01-04
JP6158266B2 (ja) 2017-07-05
EP2488871A1 (en) 2012-08-22
RU2012120104A (ru) 2013-11-27
CN102753972A (zh) 2012-10-24
WO2011045436A1 (en) 2011-04-21
RU2595843C2 (ru) 2016-08-27
JP2013507633A (ja) 2013-03-04
CA2777807A1 (en) 2011-04-21

Similar Documents

Publication Publication Date Title
CN102753972B (zh) 涉及使用磁性颗粒的测定方法和装置
RU2505816C2 (ru) Картридж для анализов с помощью магнитных частиц
US9103843B2 (en) Device and methods for detecting analytes in saliva
CA2814680C (en) Reagent storage in an assay device
JP5000666B2 (ja) 流体を分析する装置
CN101326441B (zh) 用于快速诊断的试验装置
CN104487845B (zh) 被检物质的检测系统
CN101495868A (zh) 利用磁性颗粒进行受体结合试验的装置和方法
JP2010518403A (ja) 液滴アクチュエータデバイスおよび磁性ビーズを使用する方法
EP2208531A1 (en) Distribution of particles in capillary channel by application of magnetic field
WO2011026030A1 (en) Integrated sample preparation and analyte detection
JP2014510925A (ja) 菱形の突起部を有するアッセイ装置
EP2417455A2 (en) Improved methods for conducting assays
WO2009083856A2 (en) Concentrated unbound magnetic particle assay for biosensors
KR20200141277A (ko) 면역진단 키트 및 이를 이용한 면역진단 방법
JPH0580052A (ja) 生体内物質の測定装置及び測定方法
JPH09229936A (ja) 磁性粒子を用いる被検物質の測定方法並びに該方法に使用する担体及び測定器具
CN117169519A (zh) 用于检测样本中tt3和/或tt4的解离剂和试剂盒
JPWO2015046293A1 (ja) 被検物質の検出システム
EP2875336A1 (en) Processing of a sample fluid with target components
BR112012008950A2 (pt) método de ensaio e dispositivo que envolvem o uso de partículas magnéticas
AU2023375445A1 (en) Methods for detecting target compounds and uses thereof
JPH04348277A (ja) 生体内物質の測定方法及び測定装置
JPH11326327A (ja) 粒子を使用する被検物質の測定方法及び測定器具
JPH11287803A (ja) 粒子を使用する被検物質の測定器具及び測定方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20180712

Address after: Delaware

Patentee after: J Remsen international assets LLC

Address before: Solna, Sweden

Patentee before: J&J JSC

Effective date of registration: 20180712

Address after: Solna, Sweden

Patentee after: J&J JSC

Address before: uppsala

Patentee before: AMIC AB

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20160113