CN102697803A - Cow nipple disinfectant with film forming and nursing effect, and preparation method of same - Google Patents
Cow nipple disinfectant with film forming and nursing effect, and preparation method of same Download PDFInfo
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- CN102697803A CN102697803A CN2012101834336A CN201210183433A CN102697803A CN 102697803 A CN102697803 A CN 102697803A CN 2012101834336 A CN2012101834336 A CN 2012101834336A CN 201210183433 A CN201210183433 A CN 201210183433A CN 102697803 A CN102697803 A CN 102697803A
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- milk cattle
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- 239000000645 desinfectant Substances 0.000 title claims abstract description 48
- 230000000474 nursing effect Effects 0.000 title claims abstract description 20
- 210000002445 nipple Anatomy 0.000 title abstract 5
- 238000002360 preparation method Methods 0.000 title description 7
- NLKNQRATVPKPDG-UHFFFAOYSA-M potassium iodide Chemical compound [K+].[I-] NLKNQRATVPKPDG-UHFFFAOYSA-M 0.000 claims abstract description 30
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 21
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000003974 emollient agent Substances 0.000 claims abstract description 10
- 239000004094 surface-active agent Substances 0.000 claims abstract description 8
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 claims abstract description 7
- 235000013336 milk Nutrition 0.000 claims description 61
- 239000008267 milk Substances 0.000 claims description 61
- 210000004080 milk Anatomy 0.000 claims description 61
- 241000283690 Bos taurus Species 0.000 claims description 58
- 241000780272 Mammilla Species 0.000 claims description 54
- 238000003756 stirring Methods 0.000 claims description 42
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims description 19
- 229910052740 iodine Inorganic materials 0.000 claims description 18
- 239000011630 iodine Substances 0.000 claims description 18
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 15
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 12
- 229960003260 chlorhexidine Drugs 0.000 claims description 10
- 239000000080 wetting agent Substances 0.000 claims description 9
- 229960003333 chlorhexidine gluconate Drugs 0.000 claims description 7
- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical group OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 7
- 108010010803 Gelatin Proteins 0.000 claims description 5
- 229920000159 gelatin Polymers 0.000 claims description 5
- 239000008273 gelatin Substances 0.000 claims description 5
- 235000019322 gelatine Nutrition 0.000 claims description 5
- 235000011852 gelatine desserts Nutrition 0.000 claims description 5
- SIHSSUWJKIEVGQ-UHFFFAOYSA-N 14-methyl-1-(14-methylpentadecoxy)pentadecane Chemical compound CC(C)CCCCCCCCCCCCCOCCCCCCCCCCCCCC(C)C SIHSSUWJKIEVGQ-UHFFFAOYSA-N 0.000 claims description 4
- 239000004166 Lanolin Substances 0.000 claims description 4
- 229920002565 Polyethylene Glycol 400 Polymers 0.000 claims description 4
- 239000002202 Polyethylene glycol Substances 0.000 claims description 4
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 4
- 229960002152 chlorhexidine acetate Drugs 0.000 claims description 4
- 229940039717 lanolin Drugs 0.000 claims description 4
- 235000019388 lanolin Nutrition 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- 239000002736 nonionic surfactant Substances 0.000 claims description 4
- JLFNLZLINWHATN-UHFFFAOYSA-N pentaethylene glycol Chemical compound OCCOCCOCCOCCOCCO JLFNLZLINWHATN-UHFFFAOYSA-N 0.000 claims description 4
- 229920001223 polyethylene glycol Polymers 0.000 claims description 4
- 229920000136 polysorbate Polymers 0.000 claims description 4
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 4
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 4
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 4
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 4
- MCSINKKTEDDPNK-UHFFFAOYSA-N propyl propionate Chemical compound CCCOC(=O)CC MCSINKKTEDDPNK-UHFFFAOYSA-N 0.000 claims description 4
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 claims description 3
- DNXHEGUUPJUMQT-CBZIJGRNSA-N Estrone Chemical compound OC1=CC=C2[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 DNXHEGUUPJUMQT-CBZIJGRNSA-N 0.000 claims description 3
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 claims description 3
- 239000004519 grease Substances 0.000 claims description 3
- 229940051841 polyoxyethylene ether Drugs 0.000 claims description 3
- 229920000056 polyoxyethylene ether Polymers 0.000 claims description 3
- 229940042585 tocopherol acetate Drugs 0.000 claims description 3
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 13
- 230000001954 sterilising effect Effects 0.000 abstract description 9
- 230000000694 effects Effects 0.000 abstract description 8
- 239000002085 irritant Substances 0.000 abstract description 7
- 231100000021 irritant Toxicity 0.000 abstract description 7
- 230000003385 bacteriostatic effect Effects 0.000 abstract description 4
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003906 humectant Substances 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 14
- 239000000243 solution Substances 0.000 description 11
- 239000011550 stock solution Substances 0.000 description 9
- 241000894006 Bacteria Species 0.000 description 7
- 230000000844 anti-bacterial effect Effects 0.000 description 7
- 230000005764 inhibitory process Effects 0.000 description 5
- 241000588724 Escherichia coli Species 0.000 description 4
- 241000191967 Staphylococcus aureus Species 0.000 description 4
- 241000193985 Streptococcus agalactiae Species 0.000 description 4
- 239000003085 diluting agent Substances 0.000 description 4
- 230000007794 irritation Effects 0.000 description 4
- 230000005180 public health Effects 0.000 description 4
- 210000003491 skin Anatomy 0.000 description 4
- 150000002496 iodine Chemical class 0.000 description 3
- 208000004396 mastitis Diseases 0.000 description 3
- 230000004936 stimulating effect Effects 0.000 description 3
- 238000010998 test method Methods 0.000 description 3
- 241000628997 Flos Species 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 239000000306 component Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 231100000286 mucous membrane, eye irritation or corrosion testing Toxicity 0.000 description 2
- 238000013112 stability test Methods 0.000 description 2
- VAZJLPXFVQHDFB-UHFFFAOYSA-N 1-(diaminomethylidene)-2-hexylguanidine Polymers CCCCCCN=C(N)N=C(N)N VAZJLPXFVQHDFB-UHFFFAOYSA-N 0.000 description 1
- CPKVUHPKYQGHMW-UHFFFAOYSA-N 1-ethenylpyrrolidin-2-one;molecular iodine Chemical compound II.C=CN1CCCC1=O CPKVUHPKYQGHMW-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 208000024818 Nipple disease Diseases 0.000 description 1
- 229920002413 Polyhexanide Polymers 0.000 description 1
- 229920000153 Povidone-iodine Polymers 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000000151 deposition Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 229960001621 povidone-iodine Drugs 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- 235000020185 raw untreated milk Nutrition 0.000 description 1
- UAJTZZNRJCKXJN-UHFFFAOYSA-M sodium;2-dodecoxy-2-oxoethanesulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O UAJTZZNRJCKXJN-UHFFFAOYSA-M 0.000 description 1
- 235000020354 squash Nutrition 0.000 description 1
- 238000012430 stability testing Methods 0.000 description 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to a disinfectant and particularly relates to a cow nipple disinfectant. The cow nipple disinfectant with a film forming and nursing effect comprises the following components according to weight percent: 0.1 to 0.3 of iodine, 0.1 to 0.3 of potassium iodide, 0.05 to 0.2 of hibitane, 1 to 8 of film forming agents, 2 to 8 of nonionic surface-active agents, 0.5 to 3 of emollient and 1 to 10 of humectant, and the rest is water; and all the components are mixed to form the disinfectant. The cow nipple disinfectant has a stable property, is safe and non-irritant, has the characteristics of high sterilization rate and permanent bacteriostatic action, and can form a film on the surface of a cow nipple quickly to achieve the effects of moistening and protecting.
Description
Technical field
The present invention relates to disinfectant, relate in particular to a kind of mammilla of milk cattle disinfectant.
Background technology
Milch cow is during normal activity, and the mammilla of milk cattle surface can contact and grow a large amount of antibacterials, if antibacterial falls into milk when milking, will cause the milk source to pollute.And milch cow is after milking, and mammilla of milk cattle approximately needs 1-2 hour ability closed fully, is easy to receive the invasion and attack of antibacterial therebetween, thereby brings out the generation of mastitis.Therefore the sterilization on mammilla of milk cattle surface and nursing are to improving the crucial effects that plays of raw milk's quality, prevention mammitis of cow.
The mammilla of milk cattle disinfectant has iodine class preparation, quaternary ammonium salt preparation, chlorinated product etc. in the market.The most frequently used mammilla of milk cattle disinfectant is an iodine class preparation, like povidone iodine, betagen solution etc.Abroad commonly used also is iodine class preparation, and colourless formulation such as also useful chlorhexidine gluconate, poly hexamethylene biguanide are as the succedaneum of coloured iodine class preparation.In addition, the domestic scholar of having adopts the antibacterial main constituent of Chinese medicine extract as the mammilla of milk cattle disinfectant, like the extract of Chinese herbal medicine such as Herba Houttuyniae, Flos Carthami, Fructus Cnidii, Herba Artemisiae Annuae, Fructus Forsythiae, Flos Lonicerae, Radix Bupleuri.These sterile products ubiquity working concentrations are high, obvious irritation is arranged, be prone to shortcomings such as residual contamination milk source, and lack the back of milking to the nursing role of mammilla of milk cattle, more can not keep long-acting bacteriostatic, stop antibacterial to grow at mammilla of milk cattle.
Summary of the invention
The present invention is intended to address the aforementioned drawbacks, and a kind of mammilla of milk cattle disinfectant with film forming nursing role is provided.Stable in properties of the present invention, safe and non-stimulating property, it is fast to have a sterilization speed, the persistent characteristics of bacteriostasis, and can play at the mammilla of milk cattle surface quick film-forming and moisten and protective effect.
For addressing the above problem, the present invention is achieved in that
A kind of mammilla of milk cattle disinfectant with film forming nursing role, it comprises each component of following each percetage by weight:
Iodine, 0.1-0.3;
Potassium iodide, 0.1-0.3;
Chlorhexidine, 0.05-0.2;
Film former, 1-8;
Surfactant, 2-8;
Emollient, 0.5-3;
Wetting agent, 1-10;
Water, surplus.
Described mammilla of milk cattle disinfectant is characterized in that, said chlorhexidine is chlorhexidine gluconate and/or chlorhexidine acetate.
Described mammilla of milk cattle disinfectant is characterized in that, said surfactant is to be selected from nonionic surfactant fatty alcohol-polyoxyethylene ether, TX10, the polyoxyethylene sorbitan ester one or more.
Described mammilla of milk cattle disinfectant is characterized in that, said film former is to be selected from gelatin, polyvinyl alcohol, the polyvinylpyrrolidone one or more.
Described mammilla of milk cattle disinfectant is characterized in that, said emollient is to be selected from lanolin isohexadecyl ether, Polyethylene Glycol Fructus Canarii albi grease, the Vitamin E acetate one or more.
Described mammilla of milk cattle disinfectant is characterized in that, said wetting agent is to be selected from glycerol, propylene glycol, the PEG400 one or more.
The method for preparing of described mammilla of milk cattle disinfectant is: by said content and component, iodine, potassium iodide added the suitable quantity of water stirring and dissolving, gets iodine solution, and subsequent use; The water of surplus is heated to 60-80 ℃, adds film former, stirring and dissolving; Add surfactant, stirring and dissolving; Be cooled to 25-35 ℃, add iodine solution, stirring and dissolving; Add emollient, stirring and dissolving; Add wetting agent, stirring and dissolving; Add chlorhexidine, stirring and dissolving, mix homogeneously promptly gets said mammilla of milk cattle disinfectant with film forming nursing role.
The present invention takes iodine and two kinds of sterilization components of chlorhexidine to unite use, reduces the using dosage and overall sterilization component consumption of single sterilization component, and strong to the killing bacteria ability, the preceding sterilization that is used to milk, kill bacteria fast; Amount of iodine is low during use, and is safe.Nursing after this disinfectant is used to milk, film former can form complete protecting film on the mammilla of milk cattle surface, not only effectively isolate foul, more can keep long-acting bacteriostatic, stops bacteria breed, prevents the generation of mastitis.Mammilla of milk cattle disinfectant good stability of the present invention, safe and non-stimulating property has good moist nursing role to mammilla of milk cattle, can effectively prevent cow breast epidermis and cracked nipple phenomenon.
The specific embodiment
Below, in conjunction with specific embodiment, further specify the present invention:
A kind of mammilla of milk cattle disinfectant of the present invention with film forming nursing role, it comprises each component of following each percetage by weight:
Iodine, 0.1-0.3;
Potassium iodide, 0.1-0.3;
Chlorhexidine, 0.05-0.2;
Film former, 1-8;
Surfactant, 2-8;
Emollient, 0.5-3;
Wetting agent, 1-10;
Water, surplus.
Said chlorhexidine is chlorhexidine gluconate and/or chlorhexidine acetate.
Said surfactant is to be selected from nonionic surfactant fatty alcohol-polyoxyethylene ether, TX10, the polyoxyethylene sorbitan ester one or more.
Said film former is to be selected from gelatin, polyvinyl alcohol, the polyvinylpyrrolidone one or more.
Said emollient is to be selected from lanolin isohexadecyl ether, Polyethylene Glycol Fructus Canarii albi grease, the Vitamin E acetate one or more.
Said wetting agent is to be selected from glycerol, propylene glycol, the PEG400 one or more.
The method for preparing of described mammilla of milk cattle disinfectant is: by said content and component, iodine, potassium iodide added the suitable quantity of water stirring and dissolving, gets iodine solution, and subsequent use; The water of surplus is heated to 60-80 ℃, adds film former, stirring and dissolving; Add surfactant, stirring and dissolving; Be cooled to 25-35 ℃, add iodine solution, stirring and dissolving; Add the emollient stirring and dissolving; Add wetting agent, stirring and dissolving; Add chlorhexidine, stirring and dissolving, mix homogeneously promptly gets said mammilla of milk cattle disinfectant with film forming nursing role.
Embodiment 1
Iodine 1 gram, potassium iodide 1 gram are added water 1 gram stirring and dissolving, get iodine solution, subsequent use; The water of 865 grams is heated to 60-80 ℃, adds gelatin 60 grams, stirring and dissolving; Add polyoxyethylene sorbitan ester 30 grams, stirring and dissolving; Be cooled to 25-35 ℃, add iodine solution, stirring and dissolving; Add lanolin isohexadecyl ether 10 grams, stirring and dissolving; Add propylene glycol 30 grams, stirring and dissolving; Add chlorhexidine acetate 2 grams, stirring and dissolving, mix homogeneously promptly gets said mammilla of milk cattle disinfectant.
Embodiment 2
Iodine 2 grams, potassium iodide 2 grams are added water 2 gram stirring and dissolving, get iodine solution, subsequent use; The water of 812 grams is heated to 60-80 ℃, adds polyvinyl alcohol 50 grams, stirring and dissolving; Add TX10 50 grams, stirring and dissolving; Be cooled to 25-35 ℃, add iodine solution, stirring and dissolving; Add Polyethylene Glycol olive oil ester 20 grams, stirring and dissolving; Glycerol adding 60 grams, stirring and dissolving; Add chlorhexidine gluconate 2 grams, stirring and dissolving, mix homogeneously promptly gets said mammilla of milk cattle disinfectant.
Embodiment 3
Iodine 3 grams, potassium iodide 2 grams are added water 2 gram stirring and dissolving, get iodine solution, subsequent use; The water of 782 grams is heated to 60-80 ℃, adds gelatin 40 grams and polyvinylpyrrolidone 40 grams, stirring and dissolving; Add fatty polyoxyethylenated alcohol 40 grams, stirring and dissolving; Be cooled to 25-35 ℃, add iodine solution, stirring and dissolving; Vitaminize E acetate 30 grams, stirring and dissolving; Add propylene glycol 30 grams and PEG400 30 grams, stirring and dissolving; Add chlorhexidine gluconate 1 gram, stirring and dissolving, mix homogeneously promptly gets said mammilla of milk cattle disinfectant.
Get the foregoing description mammilla of milk cattle disinfectant, carry out stability test, one-tenth film test, BA, inhibition zone test, irritation test.
Stability test: the stability testing method according to Ministry of Public Health " disinfection technology standard " (version in 2002) carries out.After depositing 3 months under 37 ℃ of conditions, the available iodine content average rate of decrease of the foregoing description mammilla of milk cattle disinfectant all 3.5%, and the content average rate of decrease of chlorhexidine gluconate all 2.0%, show that its effect duration can reach 2 years.
Become film test: after the foregoing description mammilla of milk cattle disinfectant stock solution soaks into mammilla of milk cattle, let the liquid on mammilla of milk cattle surface volatilize naturally, the mammilla of milk cattle surface can form complete softish protecting film behind the 1min.After the diluent of the foregoing description mammilla of milk cattle disinfectant (1 part of stock solution+3 part water) soaks into mammilla of milk cattle, let the liquid on mammilla of milk cattle surface volatilize naturally, the mammilla of milk cattle surface can form complete softish protecting film behind the 1min.
BA: the killing bacteria test method according to Ministry of Public Health " disinfection technology standard " (version in 2002) is carried out.The foregoing description mammilla of milk cattle disinfectant stock solution effect 1min, to staphylococcus aureus, escherichia coli, streptococcus agalactiae to kill logarithm value equal 5.00.The diluent of the foregoing description mammilla of milk cattle disinfectant (1 part of stock solution+3 part water) effect 1min, to staphylococcus aureus, escherichia coli, streptococcus agalactiae to kill logarithm value equal 5.00.
The inhibition zone test: the inhibition zone test method according to Ministry of Public Health " disinfection technology standard " (version in 2002) is carried out.The bacteria inhibition tablet of the foregoing description mammilla of milk cattle disinfectant stock solution is at 37 ℃ of incubator effect 18h, and is equal to the antibacterial ring average diameter size of staphylococcus aureus, escherichia coli, streptococcus agalactiae>16mm.The bacteria inhibition tablet of the diluent of the foregoing description mammilla of milk cattle disinfectant (1 part of stock solution+3 part water) is at 37 ℃ of incubator effect 18h, and is equal to the antibacterial ring average diameter size of staphylococcus aureus, escherichia coli, streptococcus agalactiae>13mm.
Irritation test: the irritation test method according to Ministry of Public Health " disinfection technology standard " (version in 2002) is carried out.The foregoing description mammilla of milk cattle disinfectant stock solution is nonirritant to the result of the test of rabbit intact skin irritant test, damaged skin irritant test, vaginal mucomembranous irritant test and an acute eye irritation test.The diluent of the foregoing description mammilla of milk cattle disinfectant (1 part of stock solution+3 part water) is nonirritant to the result of the test of rabbit intact skin irritant test, damaged skin irritant test, vaginal mucomembranous irritant test and an acute eye irritation test.
Like the mammilla of milk cattle disinfectant stable in properties that above-mentioned embodiment makes, the storage life is long; But stock solution is used, and also uses behind the dilutable water; The preceding sterilization that is used to milk, sterilization speed is fast, safe and non-stimulating property; Nursing can form protecting film fast after being used to milk on mammilla of milk cattle, keeps long-acting bacteriostatic, stops bacteria breed.
Claims (6)
1. mammilla of milk cattle disinfectant with film forming nursing role, it comprises each component of following each percetage by weight:
Iodine, 0.1-0.3;
Potassium iodide, 0.1-0.3;
Chlorhexidine, 0.05-0.2;
Film former, 1-8;
Nonionic surfactant, 2-8;
Emollient, 0.5-3;
Wetting agent, 1-10;
Water, surplus;
Said chlorhexidine is chlorhexidine gluconate and/or chlorhexidine acetate;
Said components is mixed said disinfectant.
2. a kind of mammilla of milk cattle disinfectant according to claim 1 with film forming nursing role; It is characterized in that said nonionic surfactant is to be selected from fatty alcohol-polyoxyethylene ether, TX10, the polyoxyethylene sorbitan ester one or more.
3. kind according to claim 1 has the mammilla of milk cattle disinfectant of film forming nursing role, it is characterized in that, said film former is to be selected from gelatin, polyvinyl alcohol, the polyvinylpyrrolidone one or more.
4. kind according to claim 1 has the mammilla of milk cattle disinfectant of film forming nursing role, it is characterized in that, said emollient is to be selected from lanolin isohexadecyl ether, Polyethylene Glycol Fructus Canarii albi grease, the Vitamin E acetate one or more.
5. kind according to claim 1 has the mammilla of milk cattle disinfectant of film forming nursing role, it is characterized in that, said wetting agent is to be selected from glycerol, propylene glycol, the PEG400 one or more.
6. according to the described arbitrary method for preparing of claim 1-5 be with mammilla of milk cattle disinfectant of film forming nursing role: by said content iodine, potassium iodide are added the suitable quantity of water stirring and dissolving, get iodine solution, subsequent use; The water of surplus is heated to 60-80 ℃, adds film former, stirring and dissolving; Add surfactant, stirring and dissolving; Be cooled to 25-35 ℃, add iodine solution, stirring and dissolving; Add emollient, stirring and dissolving; Add wetting agent, stirring and dissolving; Add chlorhexidine, stirring and dissolving, mix homogeneously promptly gets said mammilla of milk cattle disinfectant with film forming nursing role.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2012101834336A CN102697803A (en) | 2012-06-06 | 2012-06-06 | Cow nipple disinfectant with film forming and nursing effect, and preparation method of same |
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| CN2012101834336A CN102697803A (en) | 2012-06-06 | 2012-06-06 | Cow nipple disinfectant with film forming and nursing effect, and preparation method of same |
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Cited By (11)
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| CN102989033A (en) * | 2012-11-21 | 2013-03-27 | 潘军 | Additive in production for sanitary towels and pads and preparation method of additive |
| CN103462939A (en) * | 2013-09-16 | 2013-12-25 | 湖南省畜牧兽医研究所 | Povidone iodine film coating agent for treating mastitis of dairy cows and preparation method of povidone iodine film coating agent for treating mastitis of dairy cows |
| CN104055790A (en) * | 2014-06-24 | 2014-09-24 | 中国人民解放军疾病预防控制所 | Compound skin mucous membrane disinfectant, preparation method and application thereof |
| CN104622716A (en) * | 2015-02-27 | 2015-05-20 | 李航 | Medical nursing wet tissue which is non-alcoholic, long-acting, antibacterial and capable of removing dirt and disinfectant |
| CN105582538A (en) * | 2016-03-24 | 2016-05-18 | 镇江威特药业有限责任公司 | Drip-proof type dairy cow teat dipping solution and preparation method thereof |
| CN105663158A (en) * | 2016-03-15 | 2016-06-15 | 浙江海正药业股份有限公司 | High-concentration iodine disinfection solution and preparation method thereof |
| CN107308008A (en) * | 2017-06-20 | 2017-11-03 | 江苏天佑医用科技有限公司 | A kind of milk cow wipes wet tissue |
| CN108079120A (en) * | 2017-12-06 | 2018-05-29 | 常州三伊化工有限公司 | A kind of cow teats disinfectant |
| CN110711204A (en) * | 2019-10-22 | 2020-01-21 | 河北远征药业有限公司 | Iodine-glycerol nipple infusion and preparation method thereof |
| CN112616863A (en) * | 2020-12-19 | 2021-04-09 | 李慧 | Disinfectant preparation process |
| CN115814038A (en) * | 2021-12-30 | 2023-03-21 | 浙江科瑞特生物科技有限公司 | Cow nipple disinfectant and preparation method thereof |
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| CN102989033A (en) * | 2012-11-21 | 2013-03-27 | 潘军 | Additive in production for sanitary towels and pads and preparation method of additive |
| CN103462939A (en) * | 2013-09-16 | 2013-12-25 | 湖南省畜牧兽医研究所 | Povidone iodine film coating agent for treating mastitis of dairy cows and preparation method of povidone iodine film coating agent for treating mastitis of dairy cows |
| CN103462939B (en) * | 2013-09-16 | 2016-01-20 | 湖南省畜牧兽医研究所 | A kind of PVP-I for the treatment of mammitis of cow and preparation method thereof |
| CN104055790A (en) * | 2014-06-24 | 2014-09-24 | 中国人民解放军疾病预防控制所 | Compound skin mucous membrane disinfectant, preparation method and application thereof |
| CN104055790B (en) * | 2014-06-24 | 2017-12-19 | 中国人民解放军疾病预防控制所 | A kind of compound skin mucosa disinfectant and its preparation method and application |
| CN104622716A (en) * | 2015-02-27 | 2015-05-20 | 李航 | Medical nursing wet tissue which is non-alcoholic, long-acting, antibacterial and capable of removing dirt and disinfectant |
| CN105663158A (en) * | 2016-03-15 | 2016-06-15 | 浙江海正药业股份有限公司 | High-concentration iodine disinfection solution and preparation method thereof |
| CN105663158B (en) * | 2016-03-15 | 2019-06-28 | 浙江海正动物保健品有限公司 | A kind of high concentration iodic disinfecting liquid and preparation method thereof |
| CN105582538A (en) * | 2016-03-24 | 2016-05-18 | 镇江威特药业有限责任公司 | Drip-proof type dairy cow teat dipping solution and preparation method thereof |
| CN107308008A (en) * | 2017-06-20 | 2017-11-03 | 江苏天佑医用科技有限公司 | A kind of milk cow wipes wet tissue |
| CN108079120A (en) * | 2017-12-06 | 2018-05-29 | 常州三伊化工有限公司 | A kind of cow teats disinfectant |
| CN110711204A (en) * | 2019-10-22 | 2020-01-21 | 河北远征药业有限公司 | Iodine-glycerol nipple infusion and preparation method thereof |
| CN112616863A (en) * | 2020-12-19 | 2021-04-09 | 李慧 | Disinfectant preparation process |
| CN115814038A (en) * | 2021-12-30 | 2023-03-21 | 浙江科瑞特生物科技有限公司 | Cow nipple disinfectant and preparation method thereof |
| CN115814038B (en) * | 2021-12-30 | 2024-05-03 | 浙江科瑞特生物科技有限公司 | Cow nipple disinfectant and preparation method thereof |
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Application publication date: 20121003 |