CN104622716A - Medical nursing wet tissue which is non-alcoholic, long-acting, antibacterial and capable of removing dirt and disinfectant - Google Patents
Medical nursing wet tissue which is non-alcoholic, long-acting, antibacterial and capable of removing dirt and disinfectant Download PDFInfo
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- CN104622716A CN104622716A CN201510089394.7A CN201510089394A CN104622716A CN 104622716 A CN104622716 A CN 104622716A CN 201510089394 A CN201510089394 A CN 201510089394A CN 104622716 A CN104622716 A CN 104622716A
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Abstract
The invention belongs to the field of medical disinfecting products and particularly relates to a disposable medical nursing wet tissue which is non-alcoholic, long-acting, antibacterial and capable of removing dirt and taking a skin protecting effect, and a disinfectant used for the disposable medical nursing wet tissue. The disinfectant comprises the following components: chlorhexidine gluconate, a nonionic surfactant, C2-C5 polyols, polysiloxane, water and an auxiliary material. By using the disinfectant, the problems of non-perfect skin cleaning and disinfection and ultra-short skin cleaning, sterilizing and bacterium resisting time caused when the surface skin of a hospitalization patient is nursed and cleaned in the prior art are solved, the antibacterial effect of the skin of the body surface of the patient is effectively increased, the burden for cleaning the surface skin of the patient is greatly reduced, and the health problem caused by improper cleaning of the skin of the patient is avoided. The disinfectant disclosed by the invention can be independently used or is applied on a cotton swab, gauze, sponge, a medical applicator and other consumable items and devices so as to directly clean and disinfect the skin of the patient. The disinfectant is reasonable in formula and simple in use and is easily popularized.
Description
Technical field
The invention belongs to medical care sterile products field, particularly relate to a kind of nonalcoholic long acting antibiotic decontamination and play the Dispoable medical nursing wet tissue of skin care effect and the disinfectant solution of use thereof.
Background technology
Wet tissue series products is current Application comparison disposable sanitary articles widely, and cleaning for human body surface skin, therefore along with the raising of people's living standard, wet tissue is more and more very popular as a kind of product of convenience and high-efficiency.
In medical care, Nursing inpatient or make handicapped house patient always be a great difficult problem.For such patient, need cleaned at regular intervals and nursing body surface skin, prevent that the dirt of human body surface skin is too much and microbial load is too high, the effect of the treatment that impact is overall and nursing and quality, and finally cause the delay of patient's state of an illness, complicated or increase the weight of.In order to reach this object, most do not possess inpatient in the hospital ward of safe hot water bathing facility and handicapped house patient, often adopts the mode of toweling.If only use simple clear water rubbing bath mode, the effect of skin surface effective cleaning and sterilization can not be played, the effect be equal to when cannot reach common shower even far away.If want the cleaning effect reaching common shower, operate very loaded down with trivial details, at least need to prepare basin, towel, soap lye, hot water, continuous cleaning towel also picks soap lye wiping, need afterwards to use the row wiping again of enough clear hot-waters instead, loaded down with trivial details and consuming time very long, also easily cause patient to suffer from cold, the state of an illness is complicated.Meanwhile, this rubbing bath, can only decontamination to a certain degree and can not reach the effect effectively reducing body surface microbial load owing to not using effective disinfection composition, is not a kind of enough skin maintenance modes for patient.
Therefore now someone proposes and utilizes disposable wet tissue to provide cleaning and disinfection effect of surface skin for inpatient on the market, but often this series products just utilizes the general wet paper towel of commercial type to add composition of sterilizing on a small quantity again, the disinfectant solution major part of its main component all contains alcohol component, and be not suitable for all patient skins, for the patient having the skin problem such as dermatitis, eczema, the sensations such as causalgia can be produced due to stimulation during use, but also the problem such as xerosis cutis, damage can be caused.This series products often biases toward common cleaning but not effective Disinfection Effect simultaneously, positive impact is not produced to the nursing of skin yet, keep the effect of the antibacterial nursing of patient's skin surface very of short duration after use, the effect of its cleaning and disinfection is all not enough to maintain the cleaning of patient skin, reduce the health status of skin surface microbial load and maintenance skin.
In addition, the positions such as human body skin gauffer depths and pore can grow a large amount of microorganism, especially at the patient that can not obtain effective skin cleaning and nursing, these microorganisms easily form one deck " biofilm " at skin surface, and (refer to stiffly adhere on a surface of an and be difficult to by simply rinsing and the microbial cell set of the removing that rubs, wherein microorganism is mainly with the form of extracellular polysaccharide class material or wrapped up by extracellular polysaccharide class material; After in bacterial adhesion to material surface, aqueous polymers structure is by spontaneous generation and concentrate together, thus forms the structure of similar film body, the formation of these attached cells group and can cause chronic bacterial infection to the patience of antibiotic substance.Antibacterial in biofilm exists with cooperative mode being different from the antibacterial in biofilm with corresponding free bacterium in physiology, closely similar with many cells life form), antibacterial in biofilm is not easily cleaned, therefore can cause the generation of the problems such as the multi-infection of human body, difficulty be caused to effective cleaning and disinfection of skin simultaneously.In common wet tissue, for avoiding the stimulation larger to skin, contained by it, the ratio of ethanol is lower, in clinical cleaning, good cleaning and disinfection effect is not played for above-mentioned phenomenon, do not have clean and antibacterial maintenance effect, can not alleviate inpatient and handicapped house patient in the course of disease, the microorganism on its skin and biofilm are for the negative effect of health.
Summary of the invention
The present invention is directed to above-mentioned background technical problem, provide a kind of nonalcoholic long acting antibiotic decontamination, and play the Dispoable medical nursing wet tissue of skin care effect and the disinfectant solution of use thereof, to solve in prior art when nursing clean inpatient's surface skin, skin clean, sterilize perfect not, skin clean, sterilization, the problem that antibacterial timeliness is too short, and effectively enhance the antibacterial effect of patient surface skin, significantly reduce patient surface skin clean burden, and prevent patient's normal skin because of clean improper produced health problem, formula of the present invention is reasonable, use simple, be easy to promote.
For realizing the object of the invention, the technical solution used in the present invention is as follows:
A kind of disinfectant solution, is characterized in that: described disinfectant solution component comprises chlorhexidine gluconate, nonionic surfactant, C2 ~ C5 polyhydric alcohol, polysiloxanes, water and adjuvant.
Further, described adjuvant comprises one or more combinations wherein of Aloe extract, aromatic, glucono-δ-lactone.
Further, described C2 ~ C5 polyhydric alcohol is propylene glycol and/or glycerol; When adopting propylene glycol and glycerol, propylene glycol, glycerol part by weight are 1:(0.8 ~ 1.2).
Further, described disinfectant solution component also comprises hydrolytic enzyme.
Further, described hydrolytic enzyme includes but not limited to one or more combinations wherein of carbohydrase, protease, lipase; Wherein carbohydrase includes but not limited to one or more combinations wherein of amylase, cellulase and mannosidase; Protease includes but are not limited to trypsin and/or E.C. 3.4.21.64.Wherein optimal case is trypsin, and chlorhexidine gluconate and trypsin part by weight are 2:(0.1 ~ 1.1).
Further, described disinfectant solution component is counted by weight, comprises 2.5 ~ 20 part of 20% chlorhexidine gluconate, 0.6 ~ 2.4 part of nonionic surfactant, 2 ~ 4 parts of propylene glycol, 2 ~ 4 parts of glycerol, 0.6 ~ 2.4 part of polydimethylsiloxane, 1.6 ~ 2.4 parts of glucono-δ-lactones, 0.2 ~ 2.2 part of hydrolytic enzyme, 1 ~ 3 part of Aloe extract, 1 ~ 4 part of aromatic, 60 ~ 80 parts of water.
Further, described disinfectant solution component also comprises one or more combinations wherein of p-Hydroxybenzoate, IPBC, poly-methylene hydrochlorate.
Further, described p-Hydroxybenzoate includes but not limited to one or more combinations wherein of methyl parahydroxybenzoate, ethylparaben, propyl p-hydroxybenzoate, p-Hydroxybenzoic acid isopropyl ester, butyl p-hydroxybenzoate, p-Hydroxybenzoic acid isobutyl ester, P-hydroxybenzoic acid benzene methyl.
Further, described disinfectant solution component is counted by weight, comprise 2.5 ~ 20 part of 20% chlorhexidine gluconate, 0.6 ~ 2.4 part of nonionic surfactant, 4 ~ 6 parts of p-Hydroxybenzoates, 1.8 ~ 3.6 parts of IPBCs, 0.8 ~ 1.6 part of poly-methylene hydrochlorate, 2 ~ 4 parts of propylene glycol, 2 ~ 4 parts of glycerol, 0.6 ~ 2.4 part of polydimethylsiloxane, 1.6 ~ 2.4 parts of glucono-δ-lactones, 0.2 ~ 2.2 part of hydrolytic enzyme, 1 ~ 3 part of Aloe extract, 1 ~ 4 part of aromatic, 55 ~ 75 parts of water.
Further, described non-ionic surface active agent includes but not limited to one or more combinations wherein of oxo ethylene (9) nonylplenyl ether, polyoxyethylene sorbitan laurate, polyoxyethylene aliphatic alcohol ether, alkylphenol polyoxyethylene, aliphatic acid polyethenoxy fat, fatty acid methyl ester ethoxylate, alkylolamides.
Disinfectant solution in the present invention can use separately, or by disinfectant solution for consumptive material and devices such as swab stick, gauze, sponge, medical applicators, directly carries out cleaning, sterilizing for patient skin.
The present invention also proposes a kind of nonalcoholic long acting antibiotic decontamination medical nursing wet tissue, and this wet tissue is impregnated with aforementioned disinfectant solution.
Principle of the present invention is as follows:
(1) in C2 ~ C5 polyhydric alcohol:
Propylene glycol: while possessing moisture-keeping efficacy is a kind of good permeation-promoter, and dissolving power is also strong, and other composition in product can be allowed more easily to infiltrate skin surface.
Glycerol (glycerol): moisturizing, does not allow wet tissue rapid draing.
In the present invention, propylene glycol adds that both glycerol uses mutually, can reduce the vicidity of glycerol, again because of add glycerol therefore, the consumption of propylene glycol can be reduced, reduction zest, be applicable to various skin skin quality.
(2) chlorhexidine gluconate:
Molecular formula is C
34h
54cl
2n
10o
14, be a kind of antibacterial of broad-spectrum high efficacy, can work to gram-negative bacteria and gram positive bacteria simultaneously.Meanwhile, research shows, this material can keep long-acting antibacterial action on skin, can reach a few hours after first contacts.Its effect is similar to traditional chlorhexidine acetate (chlorhexidine acetate), and the chemical formula of chlorhexidine acetate is C
22h
30cl
2n
10, the structure of these two kinds of materials is similar, and sterilizing principle is identical, but these two kinds of materials but have very large difference on water solublity, and chlorhexidine gluconate can be miscible with water, and chlorhexidine acetate can only be slightly soluble in water, and larger to the zest of skin.So the present invention compares traditional disinfection liquid product significantly can reduce alcohol content when possessing same sterilization effects, act on safer on skin, non-stimulated.In instant component chlorhexidine gluconate preferably 0.5% ~ 4% disinfectant solution gross weight ratio, when chlorhexidine gluconate gross weight ratio lower than 0.5% time, for skin sterilization decreased effectiveness, sustained anti-microbial DeGrain; When chlorhexidine gluconate gross weight ratio higher than 4% time, show after deliberation not to be suitable for body surface skin.The actual usage ratio of chlorhexidine gluconate of the present invention makes suitable adjustment according to end user's body region, human body skin situation.
(3) nonionic surfactant:
Adding of nonionic surfactant, the decontamination cleaning action of wet tissue can be strengthened.Nonionic surfactant of the present invention includes but not limited to: polyoxyethylenes (9) nonylplenyl ether, polyoxyethylene sorbitan laurate, polyoxyethylene aliphatic alcohol ether, alkylphenol polyoxyethylene, aliphatic acid polyethenoxy fat, fatty acid methyl ester ethoxylate, alkylolamides.Above nonionic surfactant, while possessing surface activity enhancing decontamination cleaning action, also serves certain bactericidal action, can play synergism with chlorhexidine gluconate, possess further cleaning efficacy.
(4) polysiloxanes:
Thickness sense can be produced because chlorhexidine gluconate spreads upon on human body skin, add the function that silicones can keep sterilization while offsetting this effect, make skin feel clearly smooth.The present invention preferentially adopts polydimethylsiloxane.
(5) Aloe extract:
Anthraquinone analog compound in Aloe extract has the performance making skin contraction, softening, moisturizing, antiinflammatory, bleaching.Remove sclerosis, keratinization in addition, improve the effect of scar, little wrinkle, eye pouch, cutis laxa can not only be prevented, skin wet, tender and lovely can also be kept, simultaneously, can also scytitis be treated, also have good curative effect to acne, freckle, acne and scald, knife injury, insect bite etc.The present invention adds Aloe extract can play reparation skin after use disinfectant solution, promotes the effect of rehabilitation.
(6) glucono-δ-lactone:
The present invention adds glucono-δ-lactone, has positive effect for the stable of water quality, and overall minimizing disinfectant solution is for the stimulation of human body skin.
(7) aromatic:
Aromatic can make wet tissue and disinfectant solution have slight fragrance, increases comfort level when using.Be preferably green tea extract, while the salubrious fragrance of pleasant is provided, because of containing catechin, can sterilize and radioprotective.In medical environment, play the protective effect to human body.
(8) hydrolytic enzyme:
Hydrolytic enzyme, microorganism and the biofilms such as the antibacterial grown in a crease in the skin and pore be killed and be removed to hydrolytic enzyme can.Because the protective effect of the biofilm at human body skin gauffer and pore place, makes antibacterial wherein not easily be sterilized agent effect.Hydrolytic enzyme and chlorhexidine gluconate conbined usage, by the multiple organic compound class dirt of skin surface and biofilm hydrolysis, can reach more thoroughly deep layer sterilization comprehensively, the effect that effect is longer.In the present invention, hydrolytic enzyme includes but not limited to one or more combinations wherein of carbohydrase, protease, lipase; Wherein carbohydrase includes but not limited to one or more combinations wherein of amylase, cellulase and mannosidase; Protease includes but not limited to trypsin and/or E.C. 3.4.21.64.Discovery is studied through applicant, when employing trypsin, and trypsin and chlorhexidine gluconate weight ratio are 1:(1.8 ~ 2.2) time, cooperatively interact effect between the two, have and significantly eliminate skin surface microorganism and biofilm, deep layer sterilizing cleaning, and possess the long-time effect maintaining antibacterial action.The preferred trypsin of the present invention accounts for 0.1% ~ 1.2% of disinfectant solution gross weight ratio, when trypsin gross weight ratio lower than 0.1% time, hydrolyzed cellular tunicle effect significantly weakens; When trypsin gross weight ratio higher than 1.2% time, can have a negative impact to human body surface skin, generally not make recommendation.
(9) p-Hydroxybenzoate:
P-Hydroxybenzoate is common in the life of people as a kind of effective antiseptic and antibiotic agent, discovery is studied through applicant, p-Hydroxybenzoate and chlorhexidine gluconate mating reaction have good sterilization antibacterial action, in mould test, possess higher bactericidal effect than both arbitrary single components.The present invention adopts p-Hydroxybenzoate to include but not limited to one or more combinations wherein of methyl parahydroxybenzoate, ethylparaben, propyl p-hydroxybenzoate, p-Hydroxybenzoic acid isopropyl ester, butyl p-hydroxybenzoate, p-Hydroxybenzoic acid isobutyl ester, P-hydroxybenzoic acid benzene methyl.
(10) IPBC:
IPBC is the compound with bactericidal action, has fine antibacterial killing action, and a small amount of interpolation cooperatively interacts with p-Hydroxybenzoate and plays bactericidal action further, and does not possess stimulation to human normal skin.
(11) poly-methylene hydrochlorate:
Poly-own methylene hydrochlorate is that one is acknowledged as 21 century broad spectrum antimicrobicide the most safely and efficiently, has following characteristic: the sterilizing power with wide spectrum, particularly for the peculiar effect of all more unmanageable gram negative bacteria of general antibacterial; Quick kill bacteria; Odorless, can be attached to skin surface, continues the bacteriostasis of long period; Being in rabbit Skin Irritation Test to skin wound repair integral mean value is 0, shows that this disinfectant is to skin true border nonirritant; The insipidness when usual consumption, can not dye; Owing to keeping active on the Organic substances such as protein, fat and blood, so when there being remnant, or when uncleanly dirt exists, still keep active; Keep active in the middle part of soft water and hard water.Select a small amount of interpolation to strengthen bactericidal effect further in the present invention, and possess longer antibacterial activity with chlorhexidine gluconate combined effect and hold time.
Beneficial effect of the present invention shows:
One, medical nursing wet tissue disinfectant solution of the present invention provides a kind of cleaning sterilization means of the body surface skin for inpatient and handicapped house patient etc., possess higher sterilization, cleaning effect, and effectively can maintain antibacterial, the nursing efficacy of long period.
Two, the present invention is not containing ethanol, only plays skin moistening effect containing a small amount of polyhydric alcohol, stimulates minimum, be applicable to the cleaning-nursing of each age stratum's human body skin to human body skin.
Three, to the invention solves in prior art when clean inpatient's surface skin, skin clean, sterilization perfect not, the problem that skin clean, antibacterial timeliness are too short, and effectively enhance nursing, the bactericidal effect of patient surface skin, significantly reduce patient surface skin clean, sterilization, antibacterial nursing burden, and prevent patient's normal skin because cleaning and nursing improper produced health problem.
Four, the present invention is by selecting the hydrolytic enzyme added, cooperatively interact with chlorhexidine gluconate, the biofilm that the organic compound class dirt of skin surface and human body skin fold place and pore place produce because of microbial growth can be removed by deep layer cleaning, kill in biofilm the antibacterial that human body skin has a negative impact, and possess excellent antibacterial activity maintenance effect, suppress microorganism to be bred again and again produce biofilm and increase the microbial load of human body surface skin, the effect of impact treatment and nursing and quality, and finally cause the delay of patient's state of an illness, complicated or increase the weight of.
Five, the present invention is by selecting the p-Hydroxybenzoate, IPBC, the poly-methylene hydrochlorate that add, and improve sterilization antibacterial effect of the present invention further, the human body skin different for situation carries out adaptation.
Six, the present invention can be used on the consumptive materials such as disposable wet tissue, swab stick, gauze, sponge, medical applicator and device, directly carry out cleaning, sterilizing for patient skin, easy to use, do not need other auxiliary equipment and material, simultaneously correct use can be avoided between different patient, cross infection between the different parts of same patient.
Seven, formula of the present invention is reasonable, easy to use, stable in properties, resistance to long storage periods, provides the means of a kind of effective cleaning body surface skin and nursing skin for inpatient and handicapped house patient, broad-spectrum sterilization also can maintain long antibacterial effect, the microbial load of effective reduction human body surface skin, strengthens the treatment of hospital entirety and the effect of nursing and quality, reduces the medical expenses of whole society, and decrease the work burden of entourage, be easy to widely popularize.
Detailed description of the invention
By the following example, implementation process of the present invention and outstanding advantages can be set forth further, but the present invention is not limited to the following example.
Embodiment 1:
A kind of nonalcoholic long acting antibiotic decontamination medical nursing wet tissue disinfectant solution, described disinfectant solution component is counted by weight, comprises 10 part of 20% chlorhexidine gluconate, 2 parts of polyoxyethylenes (9) nonylplenyl ethers, 3 parts of propylene glycol, 3 parts of glycerol, 2 parts of polydimethylsiloxane, 2 parts of glucono-δ-lactones, 1 part of trypsin, 2 parts of Aloe extracts, 2 parts of aromatic, 72 parts of water.
In order to reach good disinfectant solution degree of absorption, the non-woven fabrics quality density of wet tissue is 50 to 180g/ square metre, and every sheet size is 0.03 to 0.07 square metre.Nonwoven surface is coarse structure, to increase contact area during use, can be coated on skin by solution as much as possible.
Make non-woven fabrics fully absorb the disinfectant solution prepared, reach every sheet content liquid 8 to 25 grams, different according to nonwoven thickness.During use, by modes such as the wipings to skin, be attached to by solution on skin, to reach sterilization, long acting antibiotic, whole body cleans the effect of decontamination and skin protection.
Packaged form of the present invention is wet tissue 6 to 10, is packaged in disposable packaging bag.Non-woven fabrics is acupuncture or spun-laced nonwoven fabric, and 6 to 10 wet tissue stack the most at last, is sealed in the packaging bag after sterilization.
Embodiment 2:
A kind of nonalcoholic long acting antibiotic decontamination medical nursing wet tissue disinfectant solution, described disinfectant solution component is counted by weight, comprise 5 part of 20% chlorhexidine gluconate, 0.6 part of polyoxyethylene sorbitan laurate, 2 parts of propylene glycol, 0.8 part of polydimethylsiloxane, 1.6 parts of glucono-δ-lactones, 1.5 parts of green tea extracts, 80 parts of water.
In order to reach good disinfectant solution degree of absorption, the non-woven fabrics quality density of wet tissue is 50 to 180g/ square metre, and every sheet size is 0.03 to 0.07 square metre.Nonwoven surface is coarse structure, to increase contact area during use, can be coated on skin by solution as much as possible.
Make non-woven fabrics fully absorb the disinfectant solution prepared, reach every sheet content liquid 8 to 25 grams, different according to nonwoven thickness.During use, by modes such as the wipings to skin, be attached to by solution on skin, to reach sterilization, long acting antibiotic, whole body cleans the effect of decontamination and skin protection.
Packaged form of the present invention is wet tissue 6 to 10, is packaged in disposable packaging bag.Non-woven fabrics is acupuncture or spun-laced nonwoven fabric, and 6 to 10 wet tissue stack the most at last, is sealed in the packaging bag after sterilization.
Embodiment 3:
A kind of nonalcoholic long acting antibiotic decontamination medical nursing wet tissue disinfectant solution, described disinfectant solution component is counted by weight, comprise 10 part of 20% chlorhexidine gluconate, 2 parts of polyoxyethylene aliphatic alcohol ethers, 4 parts of p-Hydroxybenzoates, 2 parts of IPBCs, 3 parts of glycerol, 2.4 parts of polydimethylsiloxane, 2 parts of amylase, cellulase and mannoside enzymatic mixtures, 3 parts of Aloe extracts, 75 parts of water.
In order to reach good disinfectant solution degree of absorption, the non-woven fabrics quality density of wet tissue is 50 to 180g/ square metre, and every sheet size is 0.03 to 0.07 square metre.Nonwoven surface is coarse structure, to increase contact area during use, can be coated on skin by solution as much as possible.
Make non-woven fabrics fully absorb the disinfectant solution prepared, reach every sheet content liquid 8 to 25 grams, different according to nonwoven thickness.During use, by modes such as the wipings to skin, be attached to by solution on skin, to reach sterilization, long acting antibiotic, whole body cleans the effect of decontamination and skin protection.
Packaged form of the present invention is wet tissue 6 to 10, is packaged in disposable packaging bag.Non-woven fabrics is acupuncture or spun-laced nonwoven fabric, and 6 to 10 wet tissue stack the most at last, is sealed in the packaging bag after sterilization.
Embodiment 4:
A kind of nonalcoholic long acting antibiotic decontamination medical nursing wet tissue disinfectant solution, described disinfectant solution component is counted by weight, comprise 18 part of 20% chlorhexidine gluconate, 2.4 parts of aliphatic acid polyethenoxy fat, 5 parts of p-Hydroxybenzoates, 2.6 parts of IPBCs, 1.2 parts of poly-methylene hydrochlorates, 3 parts of propylene glycol, 3 parts of glycerol, 2.6 parts of polydimethylsiloxane, 2.2 parts of glucono-δ-lactones, 1.2 parts of trypsin and E.C. 3.4.21.64 mixture, 3 parts of Aloe extracts, 3 parts of aromatic, 75 parts of water.
In order to reach good disinfectant solution degree of absorption, the non-woven fabrics quality density of wet tissue is 50 to 180g/ square metre, and every sheet size is 0.03 to 0.07 square metre.Nonwoven surface is coarse structure, to increase contact area during use, can be coated on skin by solution as much as possible.
Make non-woven fabrics fully absorb the disinfectant solution prepared, reach every sheet content liquid 8 to 25 grams, different according to nonwoven thickness.During use, by modes such as the wipings to skin, be attached to by solution on skin, to reach sterilization, long acting antibiotic, whole body cleans the effect of decontamination and skin protection.
Packaged form of the present invention is wet tissue 6 to 10, is packaged in disposable packaging bag.Non-woven fabrics is acupuncture or spun-laced nonwoven fabric, and 6 to 10 wet tissue stack the most at last, is sealed in the packaging bag after sterilization.
Disinfectant solution in embodiment 1 ~ 4 also can be used alone, or by disinfectant solution for consumptive material and devices such as swab stick, gauze, sponge, medical applicators, directly carries out cleaning, sterilizing for patient skin.
The present invention can summarize with other the concrete form without prejudice to spirit of the present invention or principal character.Therefore, no matter from which point, above-mentioned embodiment of the present invention all can only be thought explanation of the present invention and can not limit the present invention, claims indicate scope of the present invention, and scope of the present invention is not pointed out in above-mentioned explanation, therefore, be any change in the implication that claims of the present invention are suitable and scope, all should think to be included in the scope of claims.
Claims (12)
1. a disinfectant solution, is characterized in that: described disinfectant solution component comprises chlorhexidine gluconate, nonionic surfactant, C2 ~ C5 polyhydric alcohol, polysiloxanes, water and adjuvant.
2. a kind of disinfectant solution according to claim 1, is characterized in that: described adjuvant comprises one or more combinations wherein of Aloe extract, aromatic, glucono-δ-lactone.
3. a kind of disinfectant solution according to claim 1 and 2, is characterized in that: described C2 ~ C5 polyhydric alcohol is propylene glycol and/or glycerol; When adopting propylene glycol and glycerol, propylene glycol, glycerol part by weight are 1:(0.8 ~ 1.2).
4. a kind of disinfectant solution according to claim 3, is characterized in that: described disinfectant solution component also comprises hydrolytic enzyme.
5. a kind of disinfectant solution according to claim 4, is characterized in that: described hydrolytic enzyme comprises one or more combinations wherein of amylase, cellulase, mannosidase, trypsin, E.C. 3.4.21.64.
6. a kind of disinfectant solution according to claim 5, it is characterized in that: described disinfectant solution component is counted by weight, comprise 2.5 ~ 20 part of 20% chlorhexidine gluconate, 0.6 ~ 2.4 part of nonionic surfactant, 2 ~ 4 parts of propylene glycol, 2 ~ 4 parts of glycerol, 0.6 ~ 2.4 part of polydimethylsiloxane, 1.6 ~ 2.4 parts of glucono-δ-lactones, 0.2 ~ 2.2 part of hydrolytic enzyme, 1 ~ 3 part of Aloe extract, 1 ~ 4 part of aromatic, 55 ~ 80 parts of water.
7. a kind of disinfectant solution according to claim 4 or 6, is characterized in that: described disinfectant solution component also comprises one or more combinations wherein of p-Hydroxybenzoate, IPBC, poly-methylene hydrochlorate.
8. a kind of disinfectant solution according to claim 7, is characterized in that: described p-Hydroxybenzoate comprises one or more combinations wherein of methyl parahydroxybenzoate, ethylparaben, propyl p-hydroxybenzoate, p-Hydroxybenzoic acid isopropyl ester, butyl p-hydroxybenzoate, p-Hydroxybenzoic acid isobutyl ester, P-hydroxybenzoic acid benzene methyl.
9. a kind of disinfectant solution according to claim 7, it is characterized in that: described disinfectant solution component is counted by weight, comprise 2.5 ~ 20 part of 20% chlorhexidine gluconate, 0.6 ~ 2.4 part of nonionic surfactant, 4 ~ 6 parts of p-Hydroxybenzoates, 1.8 ~ 3.6 parts of IPBCs, 0.8 ~ 1.6 part of poly-methylene hydrochlorate, 2 ~ 4 parts of propylene glycol, 2 ~ 4 parts of glycerol, 0.6 ~ 2.4 part of polydimethylsiloxane, 1.6 ~ 2.4 parts of glucono-δ-lactones, 0.2 ~ 2.2 part of hydrolytic enzyme, 1 ~ 3 part of Aloe extract, 1 ~ 4 part of aromatic, 55 ~ 75 parts of water.
10. according to a kind of disinfectant solution of claim 1,2,4,5,6,8,9 according to any one of it, it is characterized in that: described non-ionic surface active agent comprises one or more combinations wherein of oxo ethylene (9) nonylplenyl ether, polyoxyethylene sorbitan laurate, polyoxyethylene aliphatic alcohol ether, alkylphenol polyoxyethylene, aliphatic acid polyethenoxy fat, fatty acid methyl ester ethoxylate, alkylolamides.
11. 1 kinds of nonalcoholic long acting antibiotic decontamination medical nursing wet tissues being impregnated with the arbitrary described disinfectant solution of claim 1-10.
12. 1 kinds of nonalcoholic long acting antibiotic decontamination medical solutions including the arbitrary described disinfectant solution of claim 1-10 apply equipment.
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| CN108157358A (en) * | 2018-03-02 | 2018-06-15 | 沈阳汇翼宁消毒科技有限公司 | A kind of thimerosal and preparation method thereof |
| CN109692128A (en) * | 2018-12-20 | 2019-04-30 | 扬州倍加洁日化有限公司 | A kind of antibacterial wet tissue and its production method |
| TWI683676B (en) * | 2018-12-25 | 2020-02-01 | 寶齡富錦生技股份有限公司 | Antimicrobial kit and article |
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