CN104490936A - Skin disinfectant - Google Patents
Skin disinfectant Download PDFInfo
- Publication number
- CN104490936A CN104490936A CN201410700376.3A CN201410700376A CN104490936A CN 104490936 A CN104490936 A CN 104490936A CN 201410700376 A CN201410700376 A CN 201410700376A CN 104490936 A CN104490936 A CN 104490936A
- Authority
- CN
- China
- Prior art keywords
- parts
- skin
- disinfectant liquid
- surfactant
- hibitane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention provides a skin disinfectant. The skin disinfectant comprises, by weight, 5-10 parts of chlorhexidine, 3-5 parts of perfluorocarboxylate, 5-10 parts of sodium nonylphenol polyoxyethylene ether sulfate, 20-30 parts of ethanol, 3-5 parts of beeswax, 5-10 parts of myristaldehyde, 3-5 parts of a surfactant, 1-3 parts of urea and 40-60 parts of deionized water. The skin disinfectant has no excitant smell, low toxicity, weak irritation to skin and eyes and no pollution on the environment. Through action of disinfection active components, sterilization disinfection effects are improved and sterilization efficiency is improved.
Description
Technical field
The present invention relates to disinfectant technical field, particularly a kind of disinfectant liquid for skin.
Background technology
Skin parasitic various microorganism, comprise various bacterial propagule, fungus, pathogenic bacteria etc., especially hand skin, because the chance of its contact article is more, the kind of contaminating microorganisms and quantity are also maximum, particularly the germ contamination of medical personnel's hand is even more serious, if sterilization thoroughly will not give oneself, patient and household bring disease risk, massive epidemiology survey data shows, the normally direct or indirect transmission by hand of hospital infection, this approach has more danger than air-borne transmission, therefore wash one's hands in institute to have become and reduce the most feasible most important measure of hospital infection.Investigation finds the general hand strap bacterium of medical personnel 104, suction sputum hand strap bacterium 108, hand strap of changing dressings bacterium 108 ~ 9, end bedpan hand strap bacterium 1010 ~ 11.Hands before and after making the rounds of the wards to doctor collective is monitored, and finds that the hands microbiological contamination of doctor is serious, minimum 10.8 cfu/cm2 of bacteria containing amount, the most nearly 68.2 cfu/cm2.General nursery work, as fought for patient's rapid pulse, assisting patients changes position, for patient makes the bed, operator on hand polluted bacteria number is 103 ~ 105 cfu/ handss, and defensive position of changing dressings polluted bacteria number can reach 10 cfu/ handss.Before carrying out operation, medical personnel's hand amount of bacteria mean height of nearly 50% goes out 9.5 times of standard, and content of molds reaches as high as 1 009 cfu/cm2.When being busy with one's work, hand antibacterial is multiplied, and itself and hand Carriage are under normal circumstances compared, average bacterium amount exceeds 1 times, and soprano can reach 5 600 cfu/cm2.By checking the finger of 100 nurses, detect 6 kinds, antibacterial altogether, wherein staphylococcus aureus accounts for 36%, and staphylococcus epidermidis accounts for 40%, and proteus mirabilis accounts for 8%, and Streptococcus viridans and bacillus megaterium account for 4% respectively, and Bacillus cereus accounts for 8%.Main based on staphylococcus aureus and staphylococcus epidermidis, account for 76% of sum.Obviously, the hands contact patient body of medical personnel, Excreta, articles for use are more, and content of molds and strain are also more, and all carry disease germs in any position of hands.Sterilization treatment cannot be carried out after hand contamination antibacterial, effective sterilizing methods can not be used for skin, and flora is attached to skin itself and makes a farfetched comparison and to be more difficult to remove and kill on lifeless object, therefore, concerning medical personnel, regular washing one's hands is the important means preventing foreign bacteria field planting and propagation.Effectively can reduce NIR.
Traditional hand skin sterilization has two kinds of methods: soap flowing is washed one's hands and chemosterilant sterilization.Soap sterilization is widely used, but the part that comes with some shortcomings, as more weak in boric acid class disinfectant soap disinfection force, to virus, parasite weak effect; Phenols disinfectant soap is comparatively strong to skin irritation, and to skin sensitivity and littlely have the people of wound not too applicable, and the effect of killing fungus is poor; Sulfur class disinfectant soap shortcoming suppresses sebum secretion effect comparatively strong, uses rear skin may become drier.What chemosterilant was conventional has hibitane, iodine, ethanol, glutaraldehyde etc., and they have respective pluses and minuses respectively, can not disinfection comprehensively and effectively.
One section of publication number is the preparation method disclosing a kind of composite type medical disinfectant in the patent document of CN1182533, it is by glutaraldehyde, Radix Glycyrrhizae derivant, non-ionic surface active agent, essence, deionized water forms, this disinfectant can be directly used in the washing of various trauma patient, sterilization, simultaneously to the sterilization of medical worker's operation consent, the sterilization of various medical apparatus and instruments, the sterilization of hygienic article all has function and the cleaning function of very strong killing pathogenic bacteria, simultaneously main is have promotion wound, the effect of healing, this disinfectant chemical stabilization, safety is high, without any side effects to human body skin.Glutaraldehyde is wherein the colourless transparent oil liquid with penetrating odor, is dissolved in hot water, has strong impulse effect to eyes, skin and mucosa, although bactericidal effect is good, is not suitable for skin degerming.
Summary of the invention
The object of the present invention is to provide a kind of disinfectant liquid for skin, this disinfectant liquid for skin effectively sterilize comprehensively, while stain removal bactericidal, little to skin irritation, use rear skin moist, be also applicable to skin sensitivity and littlely have wound people to use.
For solving the problems of the technologies described above, the present invention is achieved through the following technical solutions.
A kind of disinfectant liquid for skin, comprise the following compositions of following weight parts, hibitane 5-10 part, perfluorocarboxylic acid salt 3-5 part, nonylphenol polyoxyethylene ether sulfate 5-10 part, ethanol 20-30 part, Cera Flava 3-5 part, myristic aldehyde 5-10 part, surfactant 3-5 part, carbamide 1-3 part, deionized water 40-60 part.
Described disinfectant liquid for skin comprises the following composition of following weight parts: hibitane 8 parts, perfluorocarboxylic acid salt 4 parts, nonylphenol polyoxyethylene ether sulfate 8 parts, ethanol 25 parts, 4 parts, Cera Flava, myristic aldehyde 8 parts, 3 parts, surfactant, 2 parts, carbamide, deionized water 50 parts.
Described hibitane is one or both the mixture in chlorhexidine gluconate, chlorhexidine acetate.
Described chlorhexidine gluconate mixes with the ratio of chlorhexidine acetate in 3:2.
Described surfactant be CH3-(CH2)13N(CH3)2-O, octyl phenol polyoxyethylene, myristyl dimethyl amine oxide one or more.
Described disinfectant liquid for skin is prepared by following step:
(1) hibitane, perfluorocarboxylic acid salt, nonylphenol polyoxyethylene ether sulfate, ethanol, Cera Flava, myristic aldehyde, surfactant is taken by above-mentioned formula; Carbamide, deionized water, for subsequent use;
(2) will take ethanol, nonylphenol polyoxyethylene ether sulfate and surfactant, Cera Flava add in container and stir in step (1), then add in step (1) and take the stirring of hibitane, perfluorocarboxylic acid salt, myristic aldehyde and carbamide makes it dissolve completely, the deionized water added in step (1) forms homogeneous liquid.
Described step (2) operates at 30-35 DEG C.
Described Cera Flava first melts before addition.
Beneficial effect:
1, the present invention adopts hibitane, ethanol, the composite sterilization component as this disinfectant liquid for skin of these three kinds of materials of myristic aldehyde, can effectively kill each pathogenic bacteria, little to skin irritation, hibitane has bactericidal action widely, perfluorocarboxylic acid is contained as excellent surfactant in disinfectant, share with hibitane and there is synergism, hibitane bactericidal effect can be improved, nonylphenol polyoxyethylene ether sulfate has a certain amount of epoxy radicals and sulfate, therefore it has nonionic and anion surfactant double properties concurrently, clean clean effect is good, also very little to the zest of skin, the dissolubility that can also promote hibitane is share with hibitane.Skin can be made to moisten containing Cera Flava in the present invention moist, and Cera Flava has the circulation and activating cell that promote skin blood, and have the effect of antiinflammatory, particularly to there being wound to have astriction; Carbamide in the present invention has the effect of stabilizing agent, share simultaneously, play the effect to skin moisture-keeping with Cera Flava.
So disinfectant of the present invention does not have penetrating odor, toxicity low, weak to the zest of skin and eyes, environmentally safe.Simultaneously due to the mating reaction of antimicrobial activity composition, improve disinfection effect, increase germicidal efficiency.
2, the present invention adopts these two kinds of hibitane of chlorhexidine gluconate, chlorhexidine acetate, and disinfection effect is better, very little to skin irritation.Chlorhexidine gluconate, chlorhexidine acetate are used in combination with 3:2, have the effect mutually made up, and substantially 100% can kill pathogenic bacteria, because chlorhexidine gluconate is expensive, chlorhexidine acetate is cheap, used in combinationly decrease cost, simultaneously not impact effect.
Detailed description of the invention
The present invention is further illustrated below by detailed description of the invention.
Embodiment 1
A kind of disinfectant liquid for skin, comprises the following compositions of following weight parts, chlorhexidine acetate 5 parts, perfluorocarboxylic acid salt 3 parts, nonylphenol polyoxyethylene ether sulfate 5 parts, ethanol 20 parts, 3 parts, Cera Flava, myristic aldehyde 5 parts, 3 parts, surfactant; 1 part, carbamide, deionized water 40.
Embodiment 2
A kind of disinfectant liquid for skin, comprises the following compositions of following weight parts, chlorhexidine gluconate 6 parts, perfluorocarboxylic acid saline 4 parts, nonylphenol polyoxyethylene ether sulfate 6 parts, ethanol 23 parts, 4 parts, Cera Flava, myristic aldehyde 8 parts, 4 parts, surfactant; 2 parts, carbamide, deionized water 45 parts.
Embodiment 3
A kind of disinfectant liquid for skin, comprise the following compositions of following weight parts, chlorhexidine gluconate 6 parts, chlorhexidine acetate 4 parts, perfluorocarboxylic acid salt 5 parts, nonylphenol polyoxyethylene ether sulfate 10 parts, ethanol 30 parts, 5 parts, Cera Flava, myristic aldehyde 10 parts, 5 parts, surfactant; 3 parts, carbamide, deionization moisture content 60 parts
Embodiment 4
A kind of disinfectant liquid for skin, comprises the following compositions of following weight parts, hibitane 7 parts, perfluorocarboxylic acid salt 4 parts, nonylphenol polyoxyethylene ether sulfate 7 parts, ethanol 25 parts, 4 parts, Cera Flava, myristic aldehyde 8 parts, 5 parts, surfactant; 2 parts, carbamide, deionized water 50 parts.Described surfactant is myristyl dimethyl amine oxide.
Embodiment 5
A kind of disinfectant liquid for skin, comprises the following compositions of following weight parts, hibitane 8 parts, perfluorocarboxylic acid salt 4 parts, nonylphenol polyoxyethylene ether sulfate 8 parts, ethanol 28 parts, 4 parts, Cera Flava, myristic aldehyde 8 parts, 4 parts, surfactant; 2 parts, carbamide, deionization moisture content 55 parts.Described surfactant is octyl phenol polyoxyethylene.
Embodiment 6
A kind of disinfectant liquid for skin, comprises the following compositions of following weight parts, hibitane 5 parts, perfluorocarboxylic acid salt 3 parts, nonylphenol polyoxyethylene ether sulfate 5 parts, ethanol 20 parts, 3 parts, Cera Flava, myristic aldehyde 5 parts, 3 parts, surfactant; 1 part, carbamide, deionized water 40.Described surfactant is CH3-(CH2)13N(CH3)2-O.
Embodiment 7
A kind of disinfectant liquid for skin, comprises the following compositions of following weight parts, hibitane 8 parts, perfluorocarboxylic acid salt 4 parts, nonylphenol polyoxyethylene ether sulfate 8 parts, ethanol 28 parts, 4 parts, Cera Flava, myristic aldehyde 8 parts, 4 parts, surfactant; 2 parts, carbamide, deionization moisture content 55 parts.Described surfactant is CH3-(CH2)13N(CH3)2-O, octyl phenol polyoxyethylene.
Embodiment 8
A kind of disinfectant liquid for skin, comprises the following compositions of following weight parts, hibitane 8 parts, perfluorocarboxylic acid salt 4 parts, nonylphenol polyoxyethylene ether sulfate 8 parts, ethanol 28 parts, 4 parts, Cera Flava, myristic aldehyde 8 parts, 4 parts, surfactant; 2 parts, carbamide, deionization moisture content 55 parts.Described surfactant is CH3-(CH2)13N(CH3)2-O, octyl phenol polyoxyethylene, myristyl dimethyl amine oxide.
Embodiment 9
A kind of disinfectant liquid for skin, comprises the following composition of following weight parts: hibitane 8 parts, perfluorocarboxylic acid salt 4 parts, nonylphenol polyoxyethylene ether sulfate 8 parts, ethanol 25 parts, 4 parts, Cera Flava, myristic aldehyde 8 parts, 3 parts, surfactant; 2 parts, carbamide, deionized water 50 parts.
Described disinfectant liquid for skin is prepared by following step:
(1) hibitane, perfluorocarboxylic acid salt, nonylphenol polyoxyethylene ether sulfate, ethanol, Cera Flava, myristic aldehyde, surfactant is taken by above-mentioned formula; Carbamide, deionized water are for subsequent use,
(2) will take ethanol, nonylphenol polyoxyethylene ether sulfate and surfactant, Cera Flava add in container and stir in step (1), then add in step (1) and take the stirring of hibitane, perfluorocarboxylic acid salt, myristic aldehyde and carbamide makes it dissolve completely, the deionized water added in step (1) forms homogeneous liquid.
Described step (2) operates at 30-35 DEG C.
Described Cera Flava first melts before addition.
Claims (8)
1. a disinfectant liquid for skin, it is characterized in that: the following compositions comprising following weight parts, hibitane 5-10 part, perfluorocarboxylic acid salt 3-5 part, nonylphenol polyoxyethylene ether sulfate 5-10 part, ethanol 20-30 part, Cera Flava 3-5 part, myristic aldehyde 5-10 part, surfactant 3-5 part; Carbamide 1-3 part, deionized water 40-60 part.
2. a kind of disinfectant liquid for skin according to claim 1: it is characterized in that: described disinfectant liquid for skin comprises the following composition of following weight parts: hibitane 8 parts, perfluorocarboxylic acid salt 4 parts, nonylphenol polyoxyethylene ether sulfate 8 parts, ethanol 25 parts, 4 parts, Cera Flava, myristic aldehyde 8 parts, 3 parts, surfactant; 2 parts, carbamide, deionized water 50 parts.
3. a kind of disinfectant liquid for skin according to claim 1: it is characterized in that: described hibitane is one or both the mixture in chlorhexidine gluconate, chlorhexidine acetate.
4. a kind of disinfectant liquid for skin according to claim 3: it is characterized in that: described chlorhexidine gluconate mixes with the ratio of chlorhexidine acetate in 3:2.
5. a kind of disinfectant liquid for skin according to claim 1 and 2: it is characterized in that: described surfactant be CH3-(CH2)13N(CH3)2-O, octyl phenol polyoxyethylene, myristyl dimethyl amine oxide one or more.
6. a kind of disinfectant liquid for skin according to claim 1: it is characterized in that: described disinfectant liquid for skin is prepared by following step:
(1) hibitane, perfluorocarboxylic acid salt, nonylphenol polyoxyethylene ether sulfate, ethanol, Cera Flava, myristic aldehyde, surfactant is taken by above-mentioned formula; Carbamide, deionized water are for subsequent use,
(2) will take ethanol, nonylphenol polyoxyethylene ether sulfate, surfactant, Cera Flava add in container and stir in step (1), then add in step (1) and take the stirring of hibitane, perfluorocarboxylic acid salt, myristic aldehyde and carbamide makes it dissolve completely, the deionized water added in step (1) forms homogeneous liquid.
7. a kind of disinfectant liquid for skin according to claim 6: it is characterized in that: described step (2) operates at 30-35 DEG C.
8. a kind of disinfectant liquid for skin according to claim 6: it is characterized in that: described Cera Flava first melts before addition.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410700376.3A CN104490936A (en) | 2014-11-28 | 2014-11-28 | Skin disinfectant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410700376.3A CN104490936A (en) | 2014-11-28 | 2014-11-28 | Skin disinfectant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104490936A true CN104490936A (en) | 2015-04-08 |
Family
ID=52932450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410700376.3A Pending CN104490936A (en) | 2014-11-28 | 2014-11-28 | Skin disinfectant |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104490936A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105919986A (en) * | 2016-05-20 | 2016-09-07 | 蔡华英 | Fungicide |
| CN105994339A (en) * | 2016-04-26 | 2016-10-12 | 德州安捷高科消毒制品有限公司 | Special disinfectant for influenza virus |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1041687A (en) * | 1988-10-11 | 1990-05-02 | 刘庆增 | Multifunctional disinfectant |
| CN1476761A (en) * | 2003-07-02 | 2004-02-25 | 刘瑞源 | Liquid disinfectant |
| CN101310727A (en) * | 2007-05-23 | 2008-11-26 | 上海利康消毒高科技有限公司 | Alcohol-containing chlorhexidine iodine disinfectant and preparation method thereof |
| CN101336910A (en) * | 2008-08-20 | 2009-01-07 | 广州市欧替克消毒剂生产有限公司 | Chlorhexidine composition with colouring function |
| CN102085159A (en) * | 2011-01-24 | 2011-06-08 | 长沙优威生物科技有限公司 | Nursing type disinfecting liquid soap |
-
2014
- 2014-11-28 CN CN201410700376.3A patent/CN104490936A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1041687A (en) * | 1988-10-11 | 1990-05-02 | 刘庆增 | Multifunctional disinfectant |
| CN1476761A (en) * | 2003-07-02 | 2004-02-25 | 刘瑞源 | Liquid disinfectant |
| CN101310727A (en) * | 2007-05-23 | 2008-11-26 | 上海利康消毒高科技有限公司 | Alcohol-containing chlorhexidine iodine disinfectant and preparation method thereof |
| CN101336910A (en) * | 2008-08-20 | 2009-01-07 | 广州市欧替克消毒剂生产有限公司 | Chlorhexidine composition with colouring function |
| CN102085159A (en) * | 2011-01-24 | 2011-06-08 | 长沙优威生物科技有限公司 | Nursing type disinfecting liquid soap |
Non-Patent Citations (1)
| Title |
|---|
| 孙少轩 等: "《美容牙科学》", 31 January 2001, 江西高校出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105994339A (en) * | 2016-04-26 | 2016-10-12 | 德州安捷高科消毒制品有限公司 | Special disinfectant for influenza virus |
| CN105919986A (en) * | 2016-05-20 | 2016-09-07 | 蔡华英 | Fungicide |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10780037B2 (en) | Antimicrobial composition | |
| JP7286707B2 (en) | liquid cleaning composition | |
| CN101766552B (en) | Washing-free antibacterial hand sanitizer and preparation method thereof | |
| JP2008297270A (en) | Quick-drying disinfectant and method for producing the same | |
| CN101766186A (en) | Composition capable of slowly-releasing chlorine dioxide and application thereof | |
| CN104490936A (en) | Skin disinfectant | |
| CN105010390B (en) | A kind of efficient clothes disinfector | |
| CN101460053A (en) | Methods and articles having a high antiviral and antibacterial efficacy | |
| CN104435605A (en) | Preparation method of Chinese herbal medicine skin disinfectant | |
| CN104473972A (en) | Method for preparing skin disinfectant | |
| US20170265463A1 (en) | Sporicidal composition | |
| CN104784164A (en) | Protein-based skin cleaning disinfectant and preparation method thereof | |
| CN104434667A (en) | Chinese herbal medicine skin disinfectant wet wipe | |
| WO2014049370A1 (en) | Disinfectant formulation - ms71 | |
| RU2736364C2 (en) | Disinfectant composition with tartaric acid, lactic acid | |
| WO2008133717A2 (en) | Method of controlling the transmission of community-acquired-methicillin-resistant staphylococcus aureus, and preventing or reducing infections caused by the same | |
| CN104435606A (en) | Chinese herbal medicine skin disinfectant | |
| CN105010395B (en) | A kind of textile disinfecting agent | |
| CN104523454A (en) | Skin disinfection wet wipe | |
| Sˇuljagic | A Pragmatic Approach to Judicious Selection and Proper Use of Disinfectant and Antiseptic Agents in Healthcare Settings | |
| DiGangi | Cleaning and Disinfection for the Spay-Neuter Clinic |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150408 |