CN105919986A - Fungicide - Google Patents
Fungicide Download PDFInfo
- Publication number
- CN105919986A CN105919986A CN201610340857.7A CN201610340857A CN105919986A CN 105919986 A CN105919986 A CN 105919986A CN 201610340857 A CN201610340857 A CN 201610340857A CN 105919986 A CN105919986 A CN 105919986A
- Authority
- CN
- China
- Prior art keywords
- fungicide
- effect
- exist
- antibacterial
- polyglycerol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention provides a fungicide. The fungicide is prepared from, by weight, 8%-18% of chlorhexidine acetate, 10%-20% of ethanediol, 8%-16% of propyl alcohol, 8%-16% of isopropyl alcohol, 5%-7% of sodium stearyl lactate, 4%-6% of calcium stearyl lactylate, 4%-6% of diacetyl tartaric acid monoglyceride, 3%-5% of glutaraldehyde, 3%-5% of polyglycerol, 1%-3% of urea and the balance water. The fungicide is wide in antibacterial spectrum, long in use validity, wide in application and rapid and lasting in effect, the fungicide is almost not absorbed by a human body and is harmless to the human body, under the effective concentration, irritation and anaphylactic reaction on various tissues do not exist, when the fungicide and other antibiotics of sulfanilamide, penicillin and the like are used together, contraindications do not exist, and the effect is good; the effective concentration is low, fungicide resistance does not exist after the fungicide is used for a long time, and a health care effect on skin care is achieved.
Description
Technical field
The present invention relates to chemical products field, be specifically related to a kind of antibacterial.
Background technology
When human body or skin are by wound, wound is because the reason of antibacterial easily infects.The most usual
Need to use antibacterial to carry out disinfection.Existing antibacterial normally only has single disinfective action, antibacterial
Kind is few, and applicable surface is narrow.Speed of action is the slowest, is easily absorbed by organisms, has pair in various degree
Effect.And because the formula of antibacterial, some antibacterial have mild toxicity, unfavorable after being absorbed by the body
In health, during use, also have pain, have the people of allergic constitution to use and there is also anaphylaxis.And
And use effect duration that existing antibacterial also has is short, reacts slower shortcoming.
Summary of the invention
It is an object of the invention to open a kind of antibacterial, solve in above-mentioned prior art problem or
Person is multiple.
For achieving the above object, the invention provides a kind of antibacterial, include following group by weight percentage
Point: chlorhexidine acetate 8-18%, ethylene glycol 10-20%, propanol 8-16%, isopropanol 8-16%, stearic
Acyl lactylate 5-7%, CSL 4-6%, diacetyl tartarate monoglyceride 4-6%, glutaraldehyde
3-5%, polyglycerol 3-5%, carbamide 1-3%, surplus is water.
Beneficial effect: a kind of antibacterial that the present invention provides, has a broad antifungal spectrum, validity period effect is long, and purposes is wide
General, there is quick, lasting effect, be absorbed by the body hardly, harmless, in valid density
Under various tissues are had no stimulation and anaphylaxis, and when other antibiotics such as sulfanilamide, penicillin share
Without taboo, effect is more preferable；Valid density is low, and life-time service is without Drug resistance, and skin nursing is had health care
Effect.
Detailed description of the invention
Below in conjunction with each embodiment, the present invention is described in detail, but it should explanation, these are real
Executing mode not limitation of the present invention, those of ordinary skill in the art are made according to these embodiments
Equivalent transformation in function, method or structure or replacement, within belonging to protection scope of the present invention.
Embodiment 1
Get the raw materials ready: include following component by weight percentage: chlorhexidine acetate 8%, ethylene glycol 10%, third
Alcohol 8%, isopropanol 8%, sodium stearoyl lactate 5%, CSL 4%, diacetyl tartarate list
Glyceride 4%, glutaraldehyde 3%, polyglycerol 3%, carbamide 1%, surplus is water.
Chlorhexidine acetate is dissolved by spent glycol, adds propanol, isopropanol, sodium stearoyl lactate, hard
Acyl calcium lactate, diacetyl tartarate monoglyceride, be uniformly mixing to obtain mixed liquor.Add in mixed liquor
Enter glutaraldehyde, polyglycerol and carbamide, dilute.
Embodiment 2
Get the raw materials ready: include following component by weight percentage: chlorhexidine acetate 13%, ethylene glycol 15%, third
Alcohol 12%, isopropanol 12%, sodium stearoyl lactate 6%, CSL 5%, diacetyl tartarate
Monoglyceride 5%, glutaraldehyde 4%, polyglycerol 4%, carbamide 2%, surplus is water.
Chlorhexidine acetate is dissolved by spent glycol, adds propanol, isopropanol, sodium stearoyl lactate, hard
Acyl calcium lactate, diacetyl tartarate monoglyceride, be uniformly mixing to obtain mixed liquor.Add in mixed liquor
Enter glutaraldehyde, polyglycerol and carbamide, dilute.
Embodiment 3
Get the raw materials ready: include following component by weight percentage: chlorhexidine acetate 18%, ethylene glycol 20%, third
Alcohol 16%, isopropanol 16%, sodium stearoyl lactate 7%, CSL 6%, diacetyl tartarate
Monoglyceride 6%, glutaraldehyde 5%, polyglycerol 5%, carbamide 3%, surplus is water.
Chlorhexidine acetate is dissolved by spent glycol, adds propanol, isopropanol, sodium stearoyl lactate, hard
Acyl calcium lactate, diacetyl tartarate monoglyceride, be uniformly mixing to obtain mixed liquor.Add in mixed liquor
Enter glutaraldehyde, polyglycerol and carbamide, dilute.
The pharmacology of chlorhexidine acetate:
Chlorhexidine acetate has a broad antifungal spectrum, to G+Bacterium, gram negative bacteria, virus, fungus all have stronger
Bactericidal action；Nonirritant, anaphylaxis are little, also have quick, lasting, toxicity is relatively low, almost
Not being absorbed by organisms, harmless, life-time service is without advantages such as Drug resistance, so can use clinically
Sterilization in various purposes, it is adaptable to burn, scald, wound disinfection, skin degerming, operating field sterilizes,
Pre-after dermatosis, external otitis, pharyngolaryngitis, oral wounds and ulcer, operation on tonsils, tooth pulling surgery
Anti-infection and sterilization, the sterilization of infant umbilici zone, gynaecopathia sterilamp.Can also be used for sterilizing room sterilization,
The sterilization of the aspects such as medical apparatus and instruments, respond well for flu-prevention, hepatitis virus.And and penicillin,
The antibiotics such as tetracycline share without taboo, and effect is more preferable.Low cost, and have analgesic effect.
The a series of detailed description of those listed above is only for the feasibility embodiment of the present invention
Illustrating, they also are not used to limit the scope of the invention, all without departing from skill of the present invention spirit
Equivalent implementations or the change made should be included within the scope of the present invention.
Moreover, it will be appreciated that although this specification is been described by according to embodiment, but the most each reality
Mode of executing only comprises an independent technical scheme, and this narrating mode of description is only for understand
Seeing, those skilled in the art should be using description as an entirety, and the technical scheme in each embodiment is also
Other embodiments that it will be appreciated by those skilled in the art that can be formed through appropriately combined.
Claims (1)
1. an antibacterial, it is characterised in that include following component by weight percentage: chlorhexidine acetate
8-18%, ethylene glycol 10-20%, propanol 8-16%, isopropanol 8-16%, sodium stearoyl lactate 5-7%,
CSL 4-6%, diacetyl tartarate monoglyceride 4-6%, glutaraldehyde 3-5%, polyglycerol
3-5%, carbamide 1-3%, surplus is water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610340857.7A CN105919986A (en) | 2016-05-20 | 2016-05-20 | Fungicide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610340857.7A CN105919986A (en) | 2016-05-20 | 2016-05-20 | Fungicide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105919986A true CN105919986A (en) | 2016-09-07 |
Family
ID=56840986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610340857.7A Pending CN105919986A (en) | 2016-05-20 | 2016-05-20 | Fungicide |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105919986A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103142422A (en) * | 2013-03-24 | 2013-06-12 | 成都携恩科技有限公司 | Lotion for cleaning and nourishing skin surface |
| CN104490936A (en) * | 2014-11-28 | 2015-04-08 | 成都顺发消洗科技有限公司 | Skin disinfectant |
| CN105362103A (en) * | 2015-12-19 | 2016-03-02 | 南京巨鲨显示科技有限公司 | Quick-drying hand disinfection emulsion |
-
2016
- 2016-05-20 CN CN201610340857.7A patent/CN105919986A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103142422A (en) * | 2013-03-24 | 2013-06-12 | 成都携恩科技有限公司 | Lotion for cleaning and nourishing skin surface |
| CN104490936A (en) * | 2014-11-28 | 2015-04-08 | 成都顺发消洗科技有限公司 | Skin disinfectant |
| CN105362103A (en) * | 2015-12-19 | 2016-03-02 | 南京巨鲨显示科技有限公司 | Quick-drying hand disinfection emulsion |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Naik et al. | Suppl-1, M7: Ozone-A Biological Therapy in Dentistry-Reality or Myth????? | |
| JP2019189613A (en) | Materials and methods for controlling infections | |
| EP2293668B1 (en) | Antimicrobial compositions and methods of use | |
| CN104274490B (en) | Bactericidal composition including source of silver ions and menthol and application thereof | |
| Kuştarci et al. | Bactericidal effect of KTP laser irradiation against Enterococcus faecalis compared with gaseous ozone: an ex vivo study | |
| US20150264935A1 (en) | Semi-Fluidic Composition for Lubricating, Moisture Retaining, Disinfecting, Sterilizing and Method Using the Same | |
| CN101203205A (en) | Antimicrobial agents | |
| JP2018532762A (en) | Antibacterial composition for surgical use | |
| KR20150100863A (en) | Improved antimicrobial compositions | |
| Cruz et al. | Sutures coated with antiseptic pomade to prevent bacterial colonization: a randomized clinical trial | |
| Chibinski | The use of silver diamine fluoride in pediatric dentistry | |
| JP3996215B2 (en) | Disinfecting composition | |
| CN106561707A (en) | Povidone iodine effervescent tablet with sterilization and disinfection effects, and preparation method thereof | |
| CN105919986A (en) | Fungicide | |
| Ambikathanaya | Intracanal antiseptic medications; a review | |
| Jyoti et al. | Ozone in dental therapy: an outlook | |
| JP2013508457A (en) | Apparatus, methods and compositions for controlling infection | |
| CN103181931A (en) | Povidone iodine five-compound disinfectant | |
| O’Connell et al. | Unique therapies for difficult wounds | |
| WO2016077274A1 (en) | Buffered hydroalcoholic povidone iodine composition and method | |
| Bhasme et al. | Duration of surgical hand scrub in orthopaedic surgeries | |
| CN104434667A (en) | Chinese herbal medicine skin disinfectant wet wipe | |
| Elisei et al. | Some benefits of Chlorhexidine formulations | |
| CN109248320A (en) | A kind of stable high oxidation electrolyzed-oxidizing water medical ultrasonic coupling agent | |
| CN109464455A (en) | A kind of creme for preventing and treating pet body surface bacterium and fungi |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160907 |