CN102697686A - Female care solution and preparation method thereof - Google Patents
Female care solution and preparation method thereof Download PDFInfo
- Publication number
- CN102697686A CN102697686A CN2012102045898A CN201210204589A CN102697686A CN 102697686 A CN102697686 A CN 102697686A CN 2012102045898 A CN2012102045898 A CN 2012102045898A CN 201210204589 A CN201210204589 A CN 201210204589A CN 102697686 A CN102697686 A CN 102697686A
- Authority
- CN
- China
- Prior art keywords
- parts
- herba
- saururi
- folium
- feminine care
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 8
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 33
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims abstract description 33
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 33
- 239000002994 raw material Substances 0.000 claims abstract description 6
- 239000007788 liquid Substances 0.000 claims description 33
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 30
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 23
- 239000012567 medical material Substances 0.000 claims description 18
- 244000173166 Pyrus ussuriensis Species 0.000 claims description 11
- 235000011572 Pyrus ussuriensis Nutrition 0.000 claims description 11
- 238000000034 method Methods 0.000 claims description 7
- 239000000706 filtrate Substances 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 6
- 230000001105 regulatory effect Effects 0.000 claims description 4
- 230000006837 decompression Effects 0.000 claims description 2
- 238000004140 cleaning Methods 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 3
- 244000042324 Trifolium repens Species 0.000 abstract description 2
- 210000003905 vulva Anatomy 0.000 abstract description 2
- XZIIFPSPUDAGJM-UHFFFAOYSA-N 6-chloro-2-n,2-n-diethylpyrimidine-2,4-diamine Chemical compound CCN(CC)C1=NC(N)=CC(Cl)=N1 XZIIFPSPUDAGJM-UHFFFAOYSA-N 0.000 abstract 1
- 241000218691 Cupressaceae Species 0.000 abstract 1
- 241000534017 Saururus chinensis Species 0.000 abstract 1
- 235000013540 Trifolium repens var repens Nutrition 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000002085 irritant Substances 0.000 abstract 1
- 231100000021 irritant Toxicity 0.000 abstract 1
- 229940035044 sorbitan monolaurate Drugs 0.000 abstract 1
- 230000003750 conditioning effect Effects 0.000 description 11
- 239000003814 drug Substances 0.000 description 9
- 230000000844 anti-bacterial effect Effects 0.000 description 8
- 230000001580 bacterial effect Effects 0.000 description 6
- 238000010790 dilution Methods 0.000 description 6
- 239000012895 dilution Substances 0.000 description 6
- 229940079593 drug Drugs 0.000 description 6
- 230000000474 nursing effect Effects 0.000 description 6
- 241000193996 Streptococcus pyogenes Species 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 241000588724 Escherichia coli Species 0.000 description 4
- 241000191967 Staphylococcus aureus Species 0.000 description 4
- 239000003153 chemical reaction reagent Substances 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 235000015097 nutrients Nutrition 0.000 description 4
- 238000004064 recycling Methods 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 241000222122 Candida albicans Species 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 229940095731 candida albicans Drugs 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 239000004094 surface-active agent Substances 0.000 description 3
- 241001494479 Pecora Species 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- FCPVYOBCFFNJFS-LQDWTQKMSA-M benzylpenicillin sodium Chemical compound [Na+].N([C@H]1[C@H]2SC([C@@H](N2C1=O)C([O-])=O)(C)C)C(=O)CC1=CC=CC=C1 FCPVYOBCFFNJFS-LQDWTQKMSA-M 0.000 description 2
- 244000309466 calf Species 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 238000002955 isolation Methods 0.000 description 2
- 239000006210 lotion Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 1
- 238000009631 Broth culture Methods 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 241001093501 Rutaceae Species 0.000 description 1
- 241000758742 Saururaceae Species 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 239000000729 antidote Substances 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000005202 decontamination Methods 0.000 description 1
- 230000003588 decontaminative effect Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000012041 food component Nutrition 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000006916 nutrient agar Substances 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Abstract
The invention provides a female care solution, which realizes the purpose for caring private parts of the female by clearing the heat and eliminating dampness. Active ingredients of the female care solution are prepared by the following raw materials in part by weight: 10 to 30 parts of saururus chinensis, 5 to 15 parts of kamuning, 5 to 15 parts of white clover herb, 10 to 20 parts of golden cypress, 3 to 5 parts of sorbitan monolaurate, 2 to 4 parts of glycerol, and citric acid or sodium hydroxide, and the pH value is adjusted to 3.8 to 4.2. The invention also provides a preparation method of the female care solution. The female care solution has good cleaning and degerming effect and is moderate and non-irritant to the skin of the female vulva part.
Description
Technical field
The present invention relates to the female health technical field, be specifically related to a kind of feminine care liquid and preparation method thereof.
Background technology
Cleaning-nursing need be carried out with specific external nursing product in women's pudendum position; Use the medicinal lotion that mainly has the treatment function of diseases at most at present; This lotion forms by multiple extracts of Chinese herbal medicine is composite often; It mainly acts on is to be to treat various gynaecopathias, plays medicinal effect.Also have one type to be the feminine care liquid that mainly has cleaning and sterilizing function; Its main component has been the surfactant and the antibacterial that plays bactericidal action of cleaning action; Its function is cleaning and bactericidal action; But the self purification to body self has destruction simultaneously, can reduce the immunocompetence of self.Because women's privileged sites itself just need be kept certain pH value and need the flora of some to exist, with intrusion and its infringement to healthy body of resisting extraneous antibacterial.And the effect of surfactant in this type of conditioning liquid composition and antibacterial is very strong, not only fragile relatively skin is had zest, and can kill too much normal flora, destroys the sour environment of body self, reduces the self purification of self.
For overcoming the above-mentioned shortcoming of prior art; For the women provides a kind of daily nursing product that can be used for the pudendum position; Need a kind of feminine care liquid at present, not only require the effective of its cleaning and degermation, non-stimulated to the skin gentleness at female vulva position; And the effect that requires sour environment and flora environment to this position that maintenance is arranged, the while can be played nursing role.
Summary of the invention
Goal of the invention:, the object of the present invention is to provide a kind of feminine care liquid in order to address the above problem.
Another object of the present invention provides a kind of method for preparing of feminine care liquid.
Technical scheme: the objective of the invention is to realize through following scheme:
A kind of feminine care liquid; Its contained active component is prepared from the following raw materials in part by weight proportioning: Rhizoma Saururi (Herba Saururi) 10-30 part, Folium Et Cacumen Murrayae 5-15 part, Herba Trifolii Pepentis 5-15 part, Cortex Phellodendri 10-20 part, it is 3.8-4.2 that the smooth monolaurate 3-5 of Pyrusussuriensis part, glycerol 2-4 part, citric acid or sodium hydroxide are regulated pH value.
Above-mentioned feminine care liquid; Its contained active component is prepared from the following raw materials in part by weight proportioning: 20 parts of Rhizoma Saururi (Herba Saururi)s, 10 parts of Folium Et Cacumen Murrayae, 10 parts of Herba Trifolii Pepentiss, 15 parts of Cortex Phellodendris, it is 4.0 that 4 parts of the smooth monolaurates of Pyrusussuriensis, 3 parts of glycerol, citric acid or sodium hydroxide are regulated pH value.
The method of above-mentioned feminine care liquid, preparation process is: Rhizoma Saururi (Herba Saururi), Folium Et Cacumen Murrayae, Herba Trifolii Pepentis and the Cortex Phellodendri medical material of getting recipe quantity merge twice of decocte with water; Collecting decoction, relative density is 1.10-1.20 when being concentrated into 65 ℃, adds ethanol and makes the percent by volume that contains the alcohol amount reach 65-85%; Stir; Leave standstill, filter, relative density was 1.20-1.30 and reclaims ethanol when filtrate decompression was concentrated into 65 ℃; Add the smooth monolaurate of Pyrusussuriensis, G & W, use citric acid or sodium hydroxide to regulate pH value and be 3.8-4.2.
The method for preparing of above-mentioned feminine care liquid, decocting condition is: the 8-12 that adds for the first time water and be medical material weight doubly measures, and decocts 1-2h, and the 6-10 that adds water for the second time and be medical material weight doubly measures, and decocts 1-2h.。
Beneficial effect:
1, sees Rhizoma Saururi (Herba Saururi) eliminating damp-heat among the we, detumescence, detoxifcation from theory of Chinese medical science; The Folium Et Cacumen Murrayae expelling wind and removing dampness, Herba Trifolii Pepentis clearing away heat and cooling blood, Cortex Phellodendri heat clearing and damp drying, detoxifcation; Wherein Rhizoma Saururi (Herba Saururi) and Cortex Phellodendri are monarch drug, heat clearing and damp drying, and the Folium Et Cacumen Murrayae expelling wind and removing dampness is a minister, the Herba Trifolii Pepentis clearing away heat and cooling blood is an adjuvant; All medicines are harmonious, and play antipyretic and antidote functions altogether, are used for feminine care.
2, the present invention writes out a prescription reasonable in designly, and compatibility is rigorous, consists of Chinese crude drug, has no side effect low price.
3, the present invention adopts the glycerol composition of preserving moisture, and to keep and to supply with required moisture of skin and multiple nutritional components, skin is had nursing role preferably; When reaching preferably cleaning action, adopt as far as possible the low surfactant of skin irritation is prepared conditioning liquid, when reaching preferably bacteria-eliminating efficacy, farthest reduced product to the issuable injury of skin.
4, the conditioning liquid that the present invention prepared is a buffer solution system, can guarantee that the position of being nursed remains at the weakly acidic condition that pH value is 3.8-4.2, does not receive the influence of other factors.
Three kinds of functions of 5, conditioning liquid collection of the present invention cleaning, degerming, nursing are one; When stressing to clean degerming, more stress the nutrition nursing; Not only effective cleaning sterilization more can satisfy the multiple demand that privileged sites clean, safety and comfort; Have no side effect, can be used for daily cleaning-nursing for a long time.
The specific embodiment
Below through the embodiment form; Foregoing of the present invention is remake further detailed description; But should this be interpreted as that the scope of the above-mentioned theme of the present invention only limits to following instance, all technology that realizes based on foregoing of the present invention all belong to scope of the present invention.
1, combine the specific embodiment, the present invention further specified as follows:
Listed weight proportion takes by weighing raw material required for the present invention in the according to the form below, unit: part
| Rhizoma Saururi (Herba Saururi) | Folium Et Cacumen Murrayae | Herba Trifolii Pepentis | Cortex Phellodendri | The smooth monolaurate of Pyrusussuriensis | Glycerol | |
| Embodiment 1 | 10 | 15 | 5 | 20 | 3 | 4 |
| Embodiment 2 | 20 | 10 | 10 | 15 | 4 | 3 |
| Embodiment 3 | 30 | 5 | 15 | 10 | 5 | 2 |
Among the present invention, Rhizoma Saururi (Herba Saururi) is the herb of Saururaceae plant Rhizoma Saururi (Herba Saururi), and Folium Et Cacumen Murrayae is the branch and leaf of rutaceae Folium Et Cacumen Murrayae, and Herba Trifolii Pepentis is the herb of leguminous plant T.repens, and Cortex Phellodendri is the Chinese Pharmacopoeia kind.
2. preparation embodiment
2.1 get Rhizoma Saururi (Herba Saururi) 10g, Folium Et Cacumen Murrayae 15g, Herba Trifolii Pepentis 5g and Cortex Phellodendri 20g medical material and mixing, decocte with water twice adds 8 times of amounts that water is medical material weight for the first time, decocts 1h; Add for the second time 6 times of amounts that water is medical material weight, decoct 1h, collecting decoction filters; Filtrating is concentrated into relative density 1.10 (65 ℃), adds an amount of ethanol and makes and contain alcohol amount (volume fraction) and reach 65%, stirs, and leaves standstill 24 hours; Filter, filtrate recycling ethanol also is concentrated into the extractum of relative density 1.20 (65 ℃), with the smooth monolaurate 3g of Pyrusussuriensis, glycerol 4g; Water 200ml, using citric acid or sodium hydroxide to regulate pH value is 3.8, promptly gets.
2.2 get Rhizoma Saururi (Herba Saururi) 20g, Folium Et Cacumen Murrayae 10g, Herba Trifolii Pepentis 10g and Cortex Phellodendri 15g medical material and mixing, decocte with water twice adds 10 times of amounts that water is medical material weight for the first time, decocts 1.5h; Add for the second time 8 times of amounts that water is medical material weight, decoct 1.5h, collecting decoction filters; Filtrating is concentrated into relative density 1.15 (65 ℃), adds an amount of ethanol and makes and contain alcohol amount (volume fraction) and reach 75%, stirs, and leaves standstill 24 hours; Filter, filtrate recycling ethanol also is concentrated into the extractum of relative density 1.25 (65 ℃), with the smooth monolaurate 4g of Pyrusussuriensis, glycerol 3g; Water 200ml, using citric acid or sodium hydroxide to regulate pH value is 4.0, promptly gets.
2.3 get Rhizoma Saururi (Herba Saururi) 30g, Folium Et Cacumen Murrayae 5g, Herba Trifolii Pepentis 15g and Cortex Phellodendri 10g medical material and mixing, decocte with water twice adds 12 times of amounts that water is medical material weight for the first time, decocts 2h; Add for the second time 10 times of amounts that water is medical material weight, decoct 2h, collecting decoction filters; Filtrating is concentrated into relative density 1.20 (65 ℃), adds an amount of ethanol and makes and contain alcohol amount (volume fraction) and reach 85%, stirs, and leaves standstill 24 hours; Filter, filtrate recycling ethanol also is concentrated into the extractum of relative density 1.30 (65 ℃), with the smooth monolaurate 5g of Pyrusussuriensis, glycerol 2g; Water 200ml, using citric acid or sodium hydroxide to regulate pH value is 4.2, promptly gets.
3. conditioning liquid extracorporeal bacteria inhibitor test of the present invention
3.1 test material
3.1.1 medicine and reagent
Conditioning liquid of the present invention is pressed the preparation of embodiment 2 method for preparinies, promptly gets Rhizoma Saururi (Herba Saururi) 20g, Folium Et Cacumen Murrayae 10g, Herba Trifolii Pepentis 10g and Cortex Phellodendri 15g medical material and mixes twice of decocte with water; Add for the first time 10 times of amounts that water is medical material weight, decoct 1.5h, add 8 times of amounts that water is medical material weight for the second time, decoct 1.5h; Collecting decoction filters, and filtrating is concentrated into relative density 1.15 (65 ℃); Add an amount of ethanol and make and contain alcohol amount (volume fraction) and reach 75%, stir, left standstill 24 hours; Filter, filtrate recycling ethanol also is concentrated into the extractum of relative density 1.25 (65 ℃), with the smooth monolaurate 4g of Pyrusussuriensis, glycerol 3g; Water 200ml, using citric acid or sodium hydroxide to regulate pH value is 4.0, promptly gets.
Gynecological's a thousand pieces of gold washing liquid: Zhuzhou Qianjin Pharmacy Co., Ltd produces, lot number: 201005062.
Penicillin sodium: Huabei Pharmaceutic Co., Ltd's specification: 800,000 units/bottle lot number: Y1105154
Sodium chloride, Shanghai hundred million chemical reagent company limiteies of a specified duration, lot number: 00080130.
Nutrient broth, CAS Shanghai Insect Bio Technological Development Co., Ltd., lot number: 110230.
Nutrient agar, microorganism reagent factory of Jiangsu Prov. Disease Preventing and Controlling Center, lot number: 110016.
Calf serum, Hangzhou Sijiqing Biological Engineering Material Co., Ltd., lot number: 110408;
Take off fine sheep blood, available from sheep blood supply station, Nanjing, lot number: 110903
3.1.2 bacterial strain
The clinical isolates strain: staphylococcus aureus, escherichia coli, B-mode micrococcus scarlatinae, Candida albicans are provided by Jiangsu Prov. People's Hospital microbial room isolation identification.
3.1.3 instrument and equipment
Electronic balance, Beijing Sai Duolisi balance company limited is produced; The full-automatic high-pressure autoclave, Japanese SANYO; Superclean bench, Suzhou Decontamination Equipment Plant; The water isolation type constant incubator, Shanghai one permanent Science and Technology Ltd.
3.2 experimental technique
3.2.1 increasing bacterium cultivates
Get clinical isolates strain staphylococcus aureus, escherichia coli, B-mode micrococcus scarlatinae, albicans strain a little, be inoculated in respectively in the broth bouillon, cultivate 18h for 37 ℃.(adding 20% calf serum in the B-mode micrococcus scarlatinae broth bouillon) got each bacterial strain nutrient broth culture that 18h cultivates, and does the 10-3 dilution with nutrient broth and is used for experiment.
3.2.2 doubling dilution (test tube method)
Get 11 in sterilization test tube, the 1st pipe adds nutrient broth fluid medium 1.6mL, all the other every pipe 1mL; Get conditioning liquid of the present invention respectively and add in first pipe, get 1mL to the 2 pipes behind the mixing, dilution successively; The 10th pipe sucking-off 1mL discards, and the 11st pipe does not add medicinal liquid as contrast.Every pipe adds dilution bacterium liquid 0.1mL, cultivates 24h for 37 ℃, takes out the bacterial growth situation of observing.Muddy like drug liquid tube, promptly represent bacterial growth, supply the reagent thing not have bacteriostasis; Represent then that as drug liquid tube is limpid bacterial growth is suppressed, the medicinal liquid of the greatest dilution that it can bacteria growing inhibiting is the minimal inhibitory concentration (MIC) of this medicine.It is dull and stereotyped that each pipe of limpid medicinal liquid meat soup is changeed kind of bouillon agar, cultivates 24h and observe, and the minimum drug level that does not still have bacterial growth is the bacteriocidal concentration of this medicine.
Get gynecological's a thousand pieces of gold washing liquid, penicillin sodium and (be made into that 160,000 units/mL) as stated above, dilution is successively cultivated, and makes positive control.
3.3 result
Experimental result shows: conditioning liquid of the present invention all has stronger bacteriostasis to clinical isolates staphylococcus aureus, escherichia coli, B-mode micrococcus scarlatinae, Candida albicans; MIC shows that at 5mg～100mg/mL the present invention has vitro antibacterial activity.See table 1.
Table 1 conditioning liquid antibacterial activity in vitro of the present invention (n=2)
3.4 experiment conclusion
Conditioning liquid of the present invention all has stronger bacteriostasis to clinical isolates staphylococcus aureus, escherichia coli, B-mode micrococcus scarlatinae, Candida albicans, and MIC shows that at 5mg～100mg/mL conditioning liquid of the present invention has vitro antibacterial activity.
Claims (4)
1. feminine care liquid; It is characterized in that; Its contained active component is prepared from the following raw materials in part by weight proportioning: Rhizoma Saururi (Herba Saururi) 10-30 part, Folium Et Cacumen Murrayae 5-15 part, Herba Trifolii Pepentis 5-15 part, Cortex Phellodendri 10-20 part, it is 3.8-4.2 that the smooth monolaurate 3-5 of Pyrusussuriensis part, glycerol 2-4 part, citric acid or sodium hydroxide are regulated pH value.
2. feminine care liquid according to claim 1; It is characterized in that; Its contained active component is prepared from the following raw materials in part by weight proportioning: 20 parts of Rhizoma Saururi (Herba Saururi)s, 10 parts of Folium Et Cacumen Murrayae, 10 parts of Herba Trifolii Pepentiss, 15 parts of Cortex Phellodendris, it is 4.0 that 4 parts of the smooth monolaurates of Pyrusussuriensis, 3 parts of glycerol, citric acid or sodium hydroxide are regulated pH value.
3. one kind prepares the method for feminine care liquid according to claim 1, it is characterized in that preparation process is: Rhizoma Saururi (Herba Saururi), Folium Et Cacumen Murrayae, Herba Trifolii Pepentis and the Cortex Phellodendri medical material of getting recipe quantity merge twice of decocte with water; Collecting decoction, relative density is 1.10-1.20 when being concentrated into 65 ℃, adds ethanol and makes the percent by volume that contains the alcohol amount reach 65-85%; Stir; Leave standstill, filter, relative density was 1.20-1.30 and reclaims ethanol when filtrate decompression was concentrated into 65 ℃; Add the smooth monolaurate of Pyrusussuriensis, G & W, use citric acid or sodium hydroxide to regulate pH value and be 3.8-4.2.
4. according to the method for preparing of the said feminine care liquid of claim 3, it is characterized in that decocting condition is: the 8-12 that adds for the first time water and be medical material weight doubly measures, and decocts 1-2h, and the 6-10 that adds water for the second time and be medical material weight doubly measures, and decocts 1-2h.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210204589 CN102697686B (en) | 2012-06-19 | 2012-06-19 | Female care solution and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210204589 CN102697686B (en) | 2012-06-19 | 2012-06-19 | Female care solution and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102697686A true CN102697686A (en) | 2012-10-03 |
| CN102697686B CN102697686B (en) | 2013-11-06 |
Family
ID=46890940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201210204589 Expired - Fee Related CN102697686B (en) | 2012-06-19 | 2012-06-19 | Female care solution and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102697686B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104887768A (en) * | 2015-05-26 | 2015-09-09 | 徐艳 | Female traditional Chinese medicine care solution and preparation method thereof |
| CN105031077A (en) * | 2015-09-08 | 2015-11-11 | 南京正亮医药科技有限公司 | Liquid medicine used for nursing and cleaning gynaecological vulva |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1682969A (en) * | 2005-03-17 | 2005-10-19 | 桂林三金药业股份有限公司 | Medicinal composition and its preparing method and quality control method |
| CN1686504A (en) * | 2005-03-18 | 2005-10-26 | 谢义健 | anti inflammation decoction for treating morbid leucorrhea, etc. |
| CN101648003A (en) * | 2008-08-13 | 2010-02-17 | 北京和润创新医药科技发展有限公司 | Medicinal composition for treating gynecological inflammation and application thereof |
| CN101934004A (en) * | 2010-09-10 | 2011-01-05 | 重庆市南川区金佛山中药材品种培育研究所 | Chinese herbal medicament for treating urinary infections |
| CN102085292A (en) * | 2009-12-02 | 2011-06-08 | 李雄 | Medicament for treating chronic pelvic inflammation |
-
2012
- 2012-06-19 CN CN 201210204589 patent/CN102697686B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1682969A (en) * | 2005-03-17 | 2005-10-19 | 桂林三金药业股份有限公司 | Medicinal composition and its preparing method and quality control method |
| CN1686504A (en) * | 2005-03-18 | 2005-10-26 | 谢义健 | anti inflammation decoction for treating morbid leucorrhea, etc. |
| CN101648003A (en) * | 2008-08-13 | 2010-02-17 | 北京和润创新医药科技发展有限公司 | Medicinal composition for treating gynecological inflammation and application thereof |
| CN102085292A (en) * | 2009-12-02 | 2011-06-08 | 李雄 | Medicament for treating chronic pelvic inflammation |
| CN101934004A (en) * | 2010-09-10 | 2011-01-05 | 重庆市南川区金佛山中药材品种培育研究所 | Chinese herbal medicament for treating urinary infections |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104887768A (en) * | 2015-05-26 | 2015-09-09 | 徐艳 | Female traditional Chinese medicine care solution and preparation method thereof |
| CN105031077A (en) * | 2015-09-08 | 2015-11-11 | 南京正亮医药科技有限公司 | Liquid medicine used for nursing and cleaning gynaecological vulva |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102697686B (en) | 2013-11-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104940122B (en) | A kind of leave Feminine care solution and preparation method thereof | |
| CN103462881A (en) | Composite capable of promoting skin micro-ecological balance and preparation method thereof | |
| CN103417424B (en) | Plant herbal nursing gel for cleaning, conserving and protecting female and preparation method thereof | |
| CN108553355A (en) | A kind of compound houttuynin oral bacteriostasis fresh and cool spray and preparation method thereof | |
| CN102793881B (en) | Traditional Chinese medicine gel for treating vaginitis as well as preparation method and application of traditional Chinese medicine gel | |
| CN107073019A (en) | A kind of purposes of compositions for vaginal use and said composition | |
| CN106109367A (en) | A kind of toothpaste with antibacterial action containing bamboo leaf flavone and preparation method thereof | |
| CN113081928A (en) | Plant bacteriostatic gel and preparation method and application thereof | |
| CN103451032A (en) | Safe and environment-friendly tea seed washing powder and preparation method thereof | |
| CN105287790B (en) | A kind of fevervine extract and its application | |
| CN105615586A (en) | Cortex meliae-containing carpet with function of purifying air | |
| CN102697686B (en) | Female care solution and preparation method thereof | |
| CN114306526B (en) | Compound broadleaf holly leaf traditional Chinese medicine extract and application thereof in preparing shower gel or hand sanitizer | |
| CN104000767B (en) | A kind of Feminine care solution and preparation method thereof | |
| Ayele et al. | Antibacterial and antagonistic activity of selected traditional medicinal plants and herbs from East Wollega Zone against clinical isolated human pathogens | |
| CN104957952B (en) | There is the rhamnus crenata sieb.et zucc. carpet of health care function of driving mosquitoes | |
| CN104825744A (en) | Traditional Chinese medicine gel for treating vaginitis as well as preparation method and application of traditional Chinese medicine gel | |
| CN104840701A (en) | Gel for treating vaginitis | |
| CN108785383A (en) | A kind of antibacterial gynecology externally used pharmaceutical combination and the preparation method and application thereof | |
| CN110404006A (en) | A kind of pharmaceutical composition for treating chicken necrotizing enterocolitis | |
| CN108740433A (en) | A kind of Chinese herbal feed additive for three inflammation and mastitis for milk cows of sow postpartum | |
| CN108740515A (en) | A kind of Chinese herbal feed additive that can prevent animal dysentery | |
| CN104840843A (en) | Female care solution and preparation method thereof | |
| Tijani et al. | Herbominerals and antibacterial activities of Allium sativum l extracts on pathogenic bacteria causing meningitis in Sub-Saharan Africa, Zaria, Kaduna State, Nigeria | |
| KR20160069610A (en) | Method for manufacturing extracts of red ginseng and natural plant having effects for stopping hair from falling out, promoting hair growth, preventing skin aging, promoting skin regeneration, anti-inflammatory and anti-bacterial, and composition comprising the extracts |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| ASS | Succession or assignment of patent right |
Owner name: YUNNAN BIOEAST LIMITED Free format text: FORMER OWNER: BIAN YUPING Effective date: 20130930 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| C53 | Correction of patent of invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Chen Linren Inventor after: Gao Jinxing Inventor after: Su Peng Inventor before: The inventor has waived the right to be mentioned |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 211218 NANJING, JIANGSU PROVINCE TO: 650106 KUNMING, YUNNAN PROVINCE Free format text: CORRECT: INVENTOR; FROM: REQUEST NOT TO RELEASE THE NAME TO: CHEN LINREN GAO JINXING SU PENG |
|
| TA01 | Transfer of patent application right |
Effective date of registration: 20130930 Address after: 650106 No. 2199 Gao Lu, hi tech Zone, Yunnan, Kunming Applicant after: Nanjing Zhengliang Medical Technology Co., Ltd. Address before: 211218, No. 1, industrial concentrated area, Lishui county and Nanjing County, Jiangsu Applicant before: Bian Yuping |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| PP01 | Preservation of patent right |
Effective date of registration: 20170303 Granted publication date: 20131106 |
|
| PP01 | Preservation of patent right | ||
| PD01 | Discharge of preservation of patent |
Date of cancellation: 20170903 Granted publication date: 20131106 |
|
| PD01 | Discharge of preservation of patent | ||
| PP01 | Preservation of patent right |
Effective date of registration: 20170908 Granted publication date: 20131106 |
|
| PP01 | Preservation of patent right | ||
| PD01 | Discharge of preservation of patent |
Date of cancellation: 20200908 Granted publication date: 20131106 |
|
| PD01 | Discharge of preservation of patent | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20131106 Termination date: 20170619 |