CN102696645A - Pesticide composition containing pyraclostrobin and metalaxyl - Google Patents
Pesticide composition containing pyraclostrobin and metalaxyl Download PDFInfo
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- CN102696645A CN102696645A CN2012101415578A CN201210141557A CN102696645A CN 102696645 A CN102696645 A CN 102696645A CN 2012101415578 A CN2012101415578 A CN 2012101415578A CN 201210141557 A CN201210141557 A CN 201210141557A CN 102696645 A CN102696645 A CN 102696645A
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- metalaxyl
- pyraclostrobin
- composition pesticide
- pesticide
- pesticide composition
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Abstract
The invention relates to a pesticide composition containing pyraclostrobin and metalaxyl. The pesticide composition comprises common aids, pyraclostrobin and metalaxyl, wherein the mass part ratio of the pyraclostrobin to the metalaxyl is (6:1)-(1:15), preferably (4:1)-(3:25). The compound pyraclostrobin and metalaxyl have an obvious synergistic effect, so that the pesticide resistance of pathogenic bacteria of plants is delayed, the effect lasting time is long, the consumption and the using frequency of pesticide can be reduced, the cost is reduced, the use is convenient, the time and the labor are saved, and the environmental pollution is reduced. The pesticide composition is suitable for preventing and treating diseases of crops.
Description
Technical field
The composition pesticide that the present invention relates to is to be active ingredient with pyraclostrobin and Metalaxyl-M, mainly is applicable to control crops eqpidemic disease and downy mildew.
Background technology
Pyraclostrobin, english common name: pyraclostrobin, chemical formula: C
19H
18ClN
3O
4, chemical name: N-[2-[[1-(4-chlorphenyl) pyrazole-3-yl] oxygen methyl] phenyl]-N-methoxyl group methyl carbamate.Belong to methoxy acrylic bactericide; Its fungicidal spectrum wide, active high, have prevention and therapeutic action and good compatibility arranged with environment; The plurality of plant diseases that mastigomycetes, zygomycete, sac fungi, basidiomycetes, imperfect fungus are caused has good control efficiency, especially to powdery mildew, anthracnose, eqpidemic disease.Activity is high, consumption is few, is widely used in preventing and treating corps diseases.But because this series bactericidal agent action site is single, germ produces very fast to the pesticide resistance of medicament.
Metalaxyl-M, english common name: metalaxyl-M, chemical formula C
15H
21NO, chemical name N-(2, the 6-xylyl)-N-(methoxyl group acetyl group)-D-alanine methyl esters.Metalaxyl-M is the systemic fungicide with protection and therapeutic action; The synthetic inhibitor of rRNA I; Can be absorbed by the root of plant, stem, leaf, and transfer to each organ of plant, can do the cauline leaf processing with moisture content in the plant corpus; Seed treatment and soil treatment are to effective by the fungus-caused downy mildew that causes of Oomycete, eqpidemic disease disease.Simultaneously, long-term a large amount of use of this prescription agent is easy to generate pesticide resistance.
For fear of problems such as the pesticide resistance generation of using single medicament to bring, drug effect reductions, the present invention proposes the composition pesticide that contains pyraclostrobin and Metalaxyl-M.
Do not see at present pyraclostrobin and the composite report of Metalaxyl-M.
Summary of the invention
The purpose of this invention is to provide a kind of efficient, low toxicity, low-residual,, active ingredient good, lower-cost to Environmental compatibility is the composition pesticide of pyraclostrobin and Metalaxyl-M.
The present invention realizes through following technical scheme.
A kind of composition pesticide that contains pyraclostrobin and Metalaxyl-M, pyraclostrobin and the Metalaxyl-M ratio of weight and number in composition pesticide is 6:1～1:15, preferred proportion is 4:1～3:25.
Described composition pesticide adds pesticidal preparations auxiliary elements such as auxiliary agent and excipients, processes suspending agent, water dispersible granules, wetting powder according to the production technology that those skilled in the art all know.
Pesticidal preparations auxiliary elements such as said auxiliary agent and excipients comprise antifreeze, antifoaming agent, dispersant, solvent, filler etc., all are the various compositions of using or allow use in the pesticidal preparations always, and concrete composition and consumption are confirmed through testing according to the prescription requirement.
Beneficial effect of the present invention is: compare with single product, have the characteristics of binary bactericidal composition, enlarged the effective active scope; Crop downy mildew, eqpidemic disease are had the notable synergistic effect, simultaneously powdery mildew is also had the double preferably effect of controlling, and delayed drug-fast generation; Lasting period is long, has reduced dosage and access times, practices thrift cost; Easy to use, the time and labour saving, and reduce pollution to environment.
Embodiment
Below in conjunction with embodiment content of the present invention is done further to detail, mentioned content is not to qualification of the present invention among the embodiment, and material prescription is selected and can be suited measures to local conditions, and the result is not had substantial influence.In these embodiment, unless otherwise indicated, all percentages all are weight percentage.
FORMULATION EXAMPLE 1: 20% pyraclostrobin Metalaxyl-M suspending agent.
Pyraclostrobin 8%, Metalaxyl-M 12%, triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether 3%; Calcium dodecyl benzene sulfonate 3%, APES formaldehyde condensation products sulphate 2%, ethylene glycol 0.2%; Xanthan gum 0.1%, organosilicon 0.4%, glycerine 5%; Gum Arabic 0.1%, deionized water complements to 100%.Above-mentioned prescription is pulverized in proportion in advance, added in the sand mill and grind, allotment makes 20% pyraclostrobin Metalaxyl-M suspending agent after high shear mixing.
FORMULATION EXAMPLE 2: 25% pyraclostrobin Metalaxyl-M suspending agent.
Pyraclostrobin 15%, Metalaxyl-M 10%, triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether 3%; Calcium dodecyl benzene sulfonate 3%, APES formaldehyde condensation products sulphate 2%, ethylene glycol 0.2%; Xanthan gum 0.1%, organosilicon 0.4%, glycerine 5%; Gum Arabic 0.1%, deionized water complements to 100%.Above-mentioned prescription is pulverized in proportion in advance, added in the sand mill and grind, allotment makes 25% pyraclostrobin Metalaxyl-M suspending agent after high shear mixing.
FORMULATION EXAMPLE 3: 60% pyraclostrobin Metalaxyl-M water dispersible granules.
Pyraclostrobin 45%, Metalaxyl-M 15%, lauryl sodium sulfate 6%, dispersant polycarboxylate 4% disintegrant sodium chloride 2%, binding agent polyethylene glycol 3%, stable meltable property starch 3%, kaolin complements to 100%.Dry pulverization process, granulation, drying, screening preparation system promptly get 60% pyraclostrobin Metalaxyl-M water dispersible granules in proportion with above-mentioned prescription.
FORMULATION EXAMPLE 4: 50% pyraclostrobin Metalaxyl-M water dispersible granules.
Pyraclostrobin 25%, Metalaxyl-M 25%, lauryl sodium sulfate 6%, dispersant polycarboxylate 4% disintegrant sodium chloride 2%, binding agent polyethylene glycol 3%, stable meltable property starch 3%, kaolin complements to 100%.Dry pulverization process, granulation, drying, screening preparation system promptly get 50% pyraclostrobin Metalaxyl-M water dispersible granules in proportion with above-mentioned prescription.
FORMULATION EXAMPLE 5: 50% pyraclostrobin Metalaxyl-M wetting powder.
Pyraclostrobin 35%, Metalaxyl-M 15% draws back powder 3%, naphthalenesulfonate formaldehyde condensation compound 6%, talcum powder 15%, kaolin complements to 100%.Above-mentioned prescription got in the blender after the coarse crushing in proportion mix, behind comminution by gas stream, promptly make 50% pyraclostrobin Metalaxyl-M wetting powder again.
FORMULATION EXAMPLE 6: 40% pyraclostrobin Metalaxyl-M wetting powder.
Pyraclostrobin 28%, Metalaxyl-M 12% draws back powder 3%, naphthalenesulfonate formaldehyde condensation compound 6%, talcum powder 15%, kaolin complements to 100%.Above-mentioned prescription got in the blender after the coarse crushing in proportion mix, behind comminution by gas stream, promptly make 40% pyraclostrobin Metalaxyl-M wetting powder again.
Biologicall test embodiment 1: pyraclostrobin and Metalaxyl-M are mixed to the Toxicity Determination of Phytophthora capsici germ.
Adopt the mycelial growth rate method to measure.Under aseptic technique, the PDA medium that the sterilization that will melt in advance according to the test processing is cooled to about 45 ℃ quantitatively adds in the conical flask, from the low concentration to the high concentration, quantitatively draws soup successively, adds respectively in the above-mentioned conical flask, fully shakes up.To pour 3 diameters into be in the culture dish of 9cm to equivalent then, and the pastille of processing respective concentration is dull and stereotyped, and establishes the processing blank that does not contain medicament.Every processing repetition 3 times.With cultured pathogen, under aseptic condition,, cut the bacterium cake from colony edge with the sterilization card punch of diameter 5cm, with inoculator the bacterium cake is inoculated in the dull and stereotyped central authorities of pastille, mycelia faces up, and covers the ware lid, moves in (27 ± 1 ℃) insulating box and cultivates.After treating that culture dish is cultivated 4 days in insulating box, use the kind of calliper colony diameter, each bacterium colony with cross method vertical survey diameter is respectively once got its mean value.
According to survey data, calculate by following formula: bacterium colony increases diameter=colony diameter-bacterium cake diameter.
Logarithm value with drug concentration (mg/L) is independent variable x, is dependent variable y with the probit value of inhibiting rate, sets up the virulence regression equation formula respectively, adopts the EC of the single agent of DPS computed in software and each proportioning mixture
50The co-toxicity coefficient (CTC) of (95% confidence limit) and mixture, relatively synergy situation.
According to the NY/T1156.6-2006 bactericide synergy criteria for classifying: co-toxicity coefficient (CTC)>=120 shows as synergistic effect; Co-toxicity coefficient (CTC)≤80 shows as antagonism; 80＜co-toxicity coefficient (CTC)＜120 shows as summation action.
Can find out from result of the test table 1; The composition that is mixed of pyraclostrobin and Metalaxyl-M is between 6:1～1:15 at weight amount portion rate; Co-toxicity coefficient (CTC value) is all greater than 120; Promptly all showing obvious synergistic effect, is that synergistic effect is the most obvious between 4:1～3:25 at weight amount portion rate.Pyraclostrobin and Metalaxyl-M are mixed and have reasonability and feasibility, are worth carrying out field experiment and promote.
Table 1, pyraclostrobin and Metalaxyl-M are mixed to the Toxicity Determination knot of Phytophthora capsici germ
Really.
Biologicall test embodiment 2:The field control effectiveness test of control capsicum epidemic disease.
Test that autonomous county carried out in Lingshui, Hainan Province on February 12nd, 2011, the capsicum epidemic disease morbidity is converted water 45kg by every mu and carry out even spraying, dispenser twice altogether, dispenser 7 days at interval, 5 days, 14 days investigation prevention effects behind the last medicine early stage.
The field control effectiveness test result of table 2, control capsicum epidemic disease.
Can find out that from table 2 the composite bactericidal composition of pyraclostrobin Metalaxyl-M of the present invention has the better prevention effect to capsicum epidemic disease, 5 days, 14 days preventive effect all is superior to single agent of contrasting behind the last medicine.Do not find in the process of the test that the poisoning phenomenon takes place, to capsicum safety.
Biologicall test embodiment 3:The field control effectiveness test of control cucumber downy mildew.
Tested on March 15th, 2011 and carry out in Chen Jiang town, Huizhou City, Guangdong Province, the cucumber downy mildew morbidity is in earlier stage converted water 45kg by every mu and is carried out even spraying, dispenser twice altogether, dispenser 7 days at interval, 5 days, 15 days investigation prevention effects behind the last medicine.
The field control effectiveness test result of table 3, control cucumber downy mildew.
Can find out that from table 3 composition pesticide that pyraclostrobin of the present invention and Metalaxyl-M are mixed has the better prevention effect to cucumber downy mildew, 5 days, 15 days preventive effect all is superior to single agent of contrasting behind the last medicine.Simultaneously, composition pesticide of the present invention also has the good double effect of controlling to powdery mildew of cucumber.Do not find in the process of the test that the poisoning phenomenon takes place, to cucumber safety.
Can find out that from above field control effectiveness test result the composition pesticide that contains pyraclostrobin and Metalaxyl-M of the present invention all has good preventive effect to eqpidemic disease, downy mildew etc., obviously is superior to single agent; Quick-acting is good; Lasting effect is long, and is to crop safety, environmentally friendly.Compare with single agent, reduced the medication number of times, practiced thrift drug cost, so this R&D and promotion of the present invention is significant.
?
Claims (6)
1. a composition pesticide that contains pyraclostrobin and Metalaxyl-M is characterized in that active ingredient is pyraclostrobin and Metalaxyl-M.
2. a kind of composition pesticide that contains pyraclostrobin and Metalaxyl-M according to claim 1 is characterized in that: the ratio of weight and number of pyraclostrobin and Metalaxyl-M is 6:1～1:15.
3. the composition pesticide that contains pyraclostrobin and Metalaxyl-M according to claim 2 is characterized in that: the ratio of weight and number of pyraclostrobin and Metalaxyl-M is for being 4:1～3:25.
4. a kind of composition pesticide that contains pyraclostrobin and Metalaxyl-M according to claim 1 and 2 is characterized in that: also contain the pesticidal preparations auxiliary element in the described composition pesticide, be fit to the formulation that agricultural goes up use so that process.
5. a kind of agricultural chemicals group that contains pyraclostrobin and Metalaxyl-M according to claim 4
Compound is characterized in that: its formulation is suspending agent, water dispersible granules or wetting powder.
6. a kind of composition pesticide that contains pyraclostrobin and Metalaxyl-M according to claim 1 is applied to prevent and treat crops eqpidemic disease and downy mildew.
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|---|---|---|---|
| CN201210141557.8A CN102696645B (en) | 2012-05-09 | 2012-05-09 | A kind of composition pesticide containing pyraclostrobin and Metalaxyl-M |
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| CN201210141557.8A CN102696645B (en) | 2012-05-09 | 2012-05-09 | A kind of composition pesticide containing pyraclostrobin and Metalaxyl-M |
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| CN102696645B CN102696645B (en) | 2015-10-21 |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103975935A (en) * | 2014-05-28 | 2014-08-13 | 陕西上格之路生物科学有限公司 | Sterilization composition for preventing and treating soil-borne diseases of crops |
| CN105409990A (en) * | 2015-12-19 | 2016-03-23 | 青岛奥迪斯生物科技有限公司 | Sterilization composition containing pyraclostrobin and efficient metalaxyl-M |
| CN108849990A (en) * | 2018-06-27 | 2018-11-23 | 四川福思达生物技术开发有限责任公司 | A kind of agricultural medicine fertilizer composition of pyraclostrobin-containing and its application |
| CN111011390A (en) * | 2019-10-23 | 2020-04-17 | 安徽辉隆集团银山药业有限责任公司 | Seed treatment agent containing thiamethoxam, metalaxyl-M and pyraclostrobin and application thereof |
| CN112889834A (en) * | 2019-06-06 | 2021-06-04 | 上海明德立达生物科技有限公司 | Preparation method and application of metalaxyl-M-pyraclostrobin microcapsule suspending agent |
| CN113598166A (en) * | 2021-08-13 | 2021-11-05 | 石家庄农信生物科技集团有限公司 | Bactericidal granules and preparation method and application thereof |
| CN114230395A (en) * | 2021-12-16 | 2022-03-25 | 河北安格诺农化有限公司 | Slow-release pesticide-fertilizer composition and application thereof |
| CN114451420A (en) * | 2022-03-14 | 2022-05-10 | 河南豫之星作物保护有限公司 | Bactericidal composition for preventing and treating root rot |
| CN114532334A (en) * | 2022-03-31 | 2022-05-27 | 山东汤普乐作物科学有限公司 | Azole ether and fine nail cream granules and preparation method thereof |
| CN117441738A (en) * | 2023-12-26 | 2024-01-26 | 山东科赛基农生物工程有限公司 | Seed treatment suspending agent containing metalaxyl-M, pyraclostrobin and fluxapyroxad and application thereof |
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Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103975935A (en) * | 2014-05-28 | 2014-08-13 | 陕西上格之路生物科学有限公司 | Sterilization composition for preventing and treating soil-borne diseases of crops |
| CN103975935B (en) * | 2014-05-28 | 2016-08-24 | 陕西上格之路生物科学有限公司 | A kind of bactericidal composition preventing and treating crops soil-borne disease |
| CN105409990A (en) * | 2015-12-19 | 2016-03-23 | 青岛奥迪斯生物科技有限公司 | Sterilization composition containing pyraclostrobin and efficient metalaxyl-M |
| CN108849990A (en) * | 2018-06-27 | 2018-11-23 | 四川福思达生物技术开发有限责任公司 | A kind of agricultural medicine fertilizer composition of pyraclostrobin-containing and its application |
| CN112889834A (en) * | 2019-06-06 | 2021-06-04 | 上海明德立达生物科技有限公司 | Preparation method and application of metalaxyl-M-pyraclostrobin microcapsule suspending agent |
| CN111011390A (en) * | 2019-10-23 | 2020-04-17 | 安徽辉隆集团银山药业有限责任公司 | Seed treatment agent containing thiamethoxam, metalaxyl-M and pyraclostrobin and application thereof |
| CN113598166A (en) * | 2021-08-13 | 2021-11-05 | 石家庄农信生物科技集团有限公司 | Bactericidal granules and preparation method and application thereof |
| CN114230395A (en) * | 2021-12-16 | 2022-03-25 | 河北安格诺农化有限公司 | Slow-release pesticide-fertilizer composition and application thereof |
| CN114230395B (en) * | 2021-12-16 | 2022-12-06 | 河北安格诺农化有限公司 | Slow-release pesticide-fertilizer composition and application thereof |
| CN114451420A (en) * | 2022-03-14 | 2022-05-10 | 河南豫之星作物保护有限公司 | Bactericidal composition for preventing and treating root rot |
| CN114532334A (en) * | 2022-03-31 | 2022-05-27 | 山东汤普乐作物科学有限公司 | Azole ether and fine nail cream granules and preparation method thereof |
| CN114532334B (en) * | 2022-03-31 | 2023-01-03 | 山东汤普乐作物科学有限公司 | Azole ether and fine nail cream granules and preparation method thereof |
| CN117441738A (en) * | 2023-12-26 | 2024-01-26 | 山东科赛基农生物工程有限公司 | Seed treatment suspending agent containing metalaxyl-M, pyraclostrobin and fluxapyroxad and application thereof |
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| CN102696645B (en) | 2015-10-21 |
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