CN101653139A - Compound bactericidal composition containing boscalid - Google Patents
Compound bactericidal composition containing boscalid Download PDFInfo
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- CN101653139A CN101653139A CN200910161261A CN200910161261A CN101653139A CN 101653139 A CN101653139 A CN 101653139A CN 200910161261 A CN200910161261 A CN 200910161261A CN 200910161261 A CN200910161261 A CN 200910161261A CN 101653139 A CN101653139 A CN 101653139A
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- boscalid
- prochloraz
- bactericidal composition
- cyprodinil
- fluazinam
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
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Abstract
The invention relates to a bactericidal composition, the effective ingredients of which are boscalid (A) and any one (B) of prochloraz, cyprodinil and fluazinum, wherein, the mass ratio of A to B is 50:1-1:50. The A and B have obvious synergized action after being compounded, and the compound bactericidal composition can be used for preventing and treating diseases, especially fungal diseases of crops, such as fruit trees, flowers, cotton, wheat, paddy, rape, vegetables and the like,.
Description
Technical field
The present invention relates to a kind of bactericidal composition, especially a kind of combination sterilization composition that contains Boscalid.
Background technology
Gray mold is the very important disease of a class on the crops, often causes the heavy losses of crops, as gray mold of cucumber and graw mold of tomato etc.The gray mold germ is very high to humidity requirement, general May in December to next year continuous relative moisture 90% above susceptible disease.In addition, plant spacing is excessive, growth is vigorous, field closing, miscarriage all can increase the weight of the generation of this disease and spread.The south open country is sowed in spring, meet low temperature when rainy also regular meeting seriously take place and spread.
Powdery mildew also is the very important disease of a class, happens occasionally on crops such as cucumber, joint melon, wheat, grape, causes heavy losses.At present powdery mildew resistance occurred to the triazole type medicament, is badly in need of the new powdery mildew bactericide of preventing and treating.
According to the literature, because single drug and other unscientific application method have caused gray mold, powdery mildew etc. that common pesticides has been produced resistance, the increase that resistance produces back formulation rate and spraying times causes peasant burden to increase the weight of and increasing environmental pollution again.Efficiently, the novel germicide of low toxicity, environmental protection and composition thereof are one of ways of head it off.
Boscalid; English common name boscalid; chemical name: 2-chloro-N-(4 '-chlordiphenyl-2-yl) vitamin PP; it is the novel nicotinamide bactericide of BASF Aktiengesellschaft's exploitation; fungicidal spectrum is wide; have protection and therapeutic action, almost all fungies are had activity, especially efficient to gray mold, powdery mildew.Boscalid hinders tricarbonic acid cycle, the division of interference cell and growth by suppressing mitochondrial succinate dehydrogenase.Can suppress spore germination, the extension of bacterium pipe, mycelial growth and spore mother cell forms.Boscalid is the new and effective medicament of control crop gray mold and powdery mildew, but use cost is high and the risk that produces resistance arranged separately.
In view of this, the exploitation synergistic composition that contains the active ingredient Boscalid is prevented and treated gray mold, powdery mildew has reasonability and feasibility.
Summary of the invention
The objective of the invention is to: provide and use on a kind of suitable agricultural, what contain Boscalid has safety, the efficient bactericidal composite of outstanding control efficiency to gray mold, powdery mildew.
For solving the problems of the technologies described above, the inventor is by a large amount of biologicall test screenings, and unexpected discovery Boscalid and Prochloraz, cyprodinil or fluazinam are composite with certain proportion, and gray mold, powdery mildew are all had significant synergies.
On the basis of above-mentioned discovery, through composition is carried out symphyogenetic quantitative analysis, formed technical scheme of the present invention, be a kind of active ingredient (A) promptly with Boscalid, with a kind of in Prochloraz, cyprodinil, the fluazinam be another active ingredient (B), (A) be 50 with (B) mass ratio: 1-1: 50, ratio is 20 preferably: 1-1: 20.
Being described in detail as follows of described Prochloraz, cyprodinil, fluazinam:
Prochloraz, English common name Prochloraz belongs to the imidazoles broad-spectrum germicide.Crop gray mold, powdery mildew there is special efficacy.Cause effect by the biosynthesis that suppresses sterol.Though do not have a systemic action, it has certain conductive performance.
Cyprodinil; English common name Cyprodinil; chemical name 4-cyclopropyl-6-methyl-N-phenyl pyrimidine-2-amine; it is a kind of protective fungicide; the mechanism of action is the methionine biosynthesis inhibitor; after spore germination, work, stop fungi to penetrate the crop cell wall, also can suppress mycelial growth.There is not cross resistance with bactericide such as methoxy acrylic, triazole type, imidazoles, morpholine class, phenylpyrrole classes.Be mainly used in and prevent and treat gray mold, powdery mildew.
Fluazinam, English common name fluazinam is for the mitochondria phosphorous oxide is extremely dissolved coupling agent.Give sprouting, mycelia breakthrough, growth and sporulation by the inhibition spore and suppress the course of infection in all stages.
The present composition can be prepared into known method and be fit to the formulation that agricultural is used, and comprises wetting powder, water dispersible granules, suspending agent, missible oil, microemulsion, aqueous emulsion, and the total content of active ingredient is 5%-80% in the preparation.
The adjuvant that uses in the composition of the present invention comprises that dispersant, wetting agent, antifreezing agent etc. and other are of value to the known substance that active ingredient is stablized and drug effect is brought into play in storing and using, all be the various compositions of using or allow use in the pesticidal preparations always, be not particularly limited, concrete composition and consumption require to determine by simple experiment according to prescription.
Composition described in the invention can the finished product preparation form provide, and promptly each material mixes in the composition, and the composition of composition also can provide with single agent form, directly directly mixes in bucket or jar before the use, is diluted to required concentration then.
Bactericidal composition of the present invention is mainly used in disease, the especially gray mold of crops such as fruit tree, flowers, cotton, wheat, rape, vegetables and the control of powdery mildew.
Compared with prior art, the beneficial effect of the present invention's generation is: (1) is compared with single agent, and this bactericidal composition has tangible synergy to disease, has improved control efficiency; (2) can significantly reduce the field dosage, effectively reduce environmental pollution and residue of pesticide, reduce and produce and use cost; (3) mechanism of action of active ingredient is different in the bactericidal composition, has reduced the single selection pressure to germ, helps avoiding the disease resistance to produce and delay the generation speed of disease drug resistance.
Embodiment
In order to make purpose of the present invention, technical scheme and advantage clearer, the present invention describes with following specific embodiment, but the present invention is limited to these examples absolutely not.
Different pesticide active ingredients being carried out composite, is a kind of mode effectively and efficiently that solves some problems in the agricultural chemicals list agent application process at present.The agricultural chemicals of different cultivars shows three kinds of type of action after mixing usually, and promptly summation action, synergistic effect and antagonism act on but which kind of is specially, and be unpredictable, has only by a large amount of tests and just can know.Compound synergic is well filled a prescription, and can improve actual control efficiency, reduces the usage amount of agricultural chemicals, helps the generation of delaying drug resistance, is the important means of scientific prevention and cure.
The present composition is an active ingredient with a kind of (B) in Boscalid (A) and Prochloraz, cyprodinil, the fluazinam, combination has obvious role in synergism to gray mold, powdery mildew between them, and be not only the simple addition of two kinds of medicament effects, specifically be illustrated with following biologicall test example.
Biologicall test example 1: a kind of composite toxicity test in Boscalid (A) and Prochloraz, cyprodinil, the fluazinam (B) to gray mold of cucumber
Subjects: gray mold of cucumber germ (Botrytis cinerea Pers.)
Pot-culture method is adopted in this test.Sowing sense gray mold of cucumber kind potted plantly grows to 2-4 leaf periods, numbers standby.On the basis of preliminary experiment,, 5-7 series mass concentration is set according to the medicament activity.Every processing 4 basins evenly spray in the blade face 10ml soup to all wetting, treat that the soup natural air drying is standby.And establish the processing that only contains solvent and surfactant and do not contain effective composition and make blank.Behind the chemicals treatment 24h, on cucumber leaves, evenly spray inoculation botrytis cinerea pers conidial suspension with the crop sprayer.Botrytis cinerea pers conidial suspension process for preparation is as follows: test, washes spore with sterile water after being cultured to a large amount of spores of generation on the suitable culture base with pathogen, filters with double gauze, is modulated into 1 * 10 behind the microscopy
5Individual spore/mL spore suspension (adding a little surfactant) in order to adhering to.Move in the humidistat (relative moisture more than 95%, temperature 20-22 ℃) dark condition after the inoculation and cultivate 24h down, under 20-25 ℃, relative moisture 80%-90% condition, cultivated 7 days then.Add up the lesion area on every strain cucumber leaves, calculate disease index and control efficiency.16 leaves of every processing investigation, stage division is:
The gray mold of cucumber grade scale
0 grade: blade does not have scab;
1 grade: lesion area accounts for below 5% of whole blade area;
3 grades: lesion area accounts for the 6-15% of whole blade area;
5 grades: lesion area accounts for the 16-25% of whole blade area;
7 grades: lesion area accounts for the 26-50% of whole blade area;
9 grades: lesion area accounts for more than 50% of whole blade area.
The drug effect computational methods:
Control efficiency is converted into probability value (y), and liquor strength (μ g/ml) converts logarithm value (x) to, calculates concentration EC in virulence equation and the inhibition with method of least squares
50, according to the toxicity index and the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun medicament.
Actual measurement toxicity index (ATI)=(standard medicament EC
50/ reagent agent EC
50) * 100
The percentage composition of B in percentage composition+B medicament toxicity index * mixture of A in theoretical toxicity index (TTI)=A medicament toxicity index * mixture
Co-toxicity coefficient (CTC)=[mixture actual measurement toxicity index (the ATI)/theoretical toxicity index (TTI) of mixture] * 100
When CTC≤80, then the composition performance is antagonism; When 80＜CTC＜120, then the composition performance is summation action; When CTC 〉=120, then the composition performance is synergistic effect.
Toxicity test result referring to table 1 to table 3
The serial proportioning of table 1 Boscalid and Prochloraz is to the pot experiment measurement result of gray mold of cucumber
| Handle | ??EC 50(μg/mL) | ??ATI | ??TTI | Co-toxicity coefficient CTC |
| Boscalid | ??18.26 | ??100 | ??/ | ??/ |
| Prochloraz | ??20.46 | ??89.2 | ??/ | ??/ |
| Boscalid 50: Prochloraz 1 | ??13.43 | ??136.0 | ??99.8 | ??136.3 |
| Boscalid 20: Prochloraz 1 | ??10.32 | ??176.9 | ??99.5 | ??177.8 |
| Boscalid 10: Prochloraz 1 | ??9.28 | ??196.8 | ??99.0 | ??198.7 |
| Boscalid 5: Prochloraz 1 | ??8.24 | ??221.6 | ??98.2 | ??225.6 |
| Boscalid 1: Prochloraz 1 | ??6.39 | ??285.8 | ??94.6 | ??302.0 |
| Boscalid 1: Prochloraz 5 | ??8.22 | ??222.1 | ??91.0 | ??244.0 |
| Boscalid 1: Prochloraz 10 | ??9.81 | ??186.1 | ??90.2 | ??206.3 |
| Boscalid 1: Prochloraz 20 | ??10.86 | ??168.1 | ??89.8 | ??187.3 |
| Boscalid 1: Prochloraz 50 | ??14.55 | ??125.5 | ??89.5 | ??140.3 |
Result of the test shows, the composite control gray mold of cucumber of Boscalid and Prochloraz, and proportioning is 50: 1-1: in the time of between 50, co-toxicity coefficient has synergistic effect more than 136.3; Proportioning is 20: 1-1: in the time of between 20, co-toxicity coefficient all is higher than 177.8, and synergistic effect is more obvious.
The serial proportioning of table 2 Boscalid and cyprodinil is to the pot experiment measurement result of gray mold of cucumber
| Handle | ??EC 50(μg/mL) | ??ATI | ??TTI | Co-toxicity coefficient CTC |
| Boscalid | ??18.26 | ??100 | ??/ | ??/ |
| Cyprodinil | ??18.46 | ??98.9 | ??/ | ??/ |
| Boscalid 50: cyprodinil 1 | ??12.43 | ??146.9 | ??100.0 | ??146.9 |
| Boscalid 20: cyprodinil 1 | ??9.32 | ??195.9 | ??99.9 | ??196.0 |
| Boscalid 10: cyprodinil 1 | ??8.28 | ??220.5 | ??99.9 | ??220.7 |
| Boscalid 5: cyprodinil 1 | ??7.24 | ??252.2 | ??99.8 | ??252.7 |
| Boscalid 1: cyprodinil 1 | ??5.39 | ??338.8 | ??99.5 | ??340.6 |
| Boscalid 1: cyprodinil 5 | ??8.12 | ??224.9 | ??99.1 | ??226.9 |
| Boscalid 1: cyprodinil 10 | ??8.81 | ??207.3 | ??99.0 | ??209.3 |
| Boscalid 1: cyprodinil 20 | ??9.86 | ??185.2 | ??99.0 | ??187.1 |
| Boscalid 1: cyprodinil 50 | ??13.55 | ??134.8 | ??98.9 | ??136.2 |
Result of the test shows, the composite control gray mold of cucumber of Boscalid and cyprodinil, and proportioning is 50: 1-1: in the time of between 50, co-toxicity coefficient has synergistic effect more than 136.2; Proportioning is 20: 1-1: in the time of between 20, co-toxicity coefficient all is higher than 187.1, and synergistic effect is more obvious.
The serial proportioning of table 3 Boscalid and fluazinam is to the pot experiment measurement result of gray mold of cucumber
| Handle | ??EC 50(μg/mL) | ??ATI | ??TTI | Co-toxicity coefficient CTC |
| Boscalid | ??18.26 | ??100 | ??/ | ??/ |
| Fluazinam | ??16.46 | ??110.9 | ??/ | ??/ |
| Boscalid 50: fluazinam 1 | ??13.43 | ??136.0 | ??100.2 | ??135.7 |
| Boscalid 20: fluazinam 1 | ??10.12 | ??180.4 | ??100.5 | ??179.5 |
| Boscalid 10: fluazinam 1 | ??9.28 | ??196.8 | ??101.0 | ??194.8 |
| Boscalid 5: fluazinam 1 | ??8.24 | ??221.6 | ??101.8 | ??217.6 |
| Boscalid 1: fluazinam 1 | ??6.39 | ??285.8 | ??105.5 | ??270.9 |
| Boscalid 1: fluazinam 5 | ??8.02 | ??227.7 | ??109.1 | ??208.7 |
| Boscalid 1: fluazinam 10 | ??8.81 | ??207.3 | ??109.9 | ??188.5 |
| Boscalid 1: fluazinam 20 | ??9.26 | ??197.2 | ??110.4 | ??178.6 |
| Boscalid 1: fluazinam 50 | ??12.35 | ??147.9 | ??110.7 | ??133.5 |
Result of the test shows, the composite control gray mold of cucumber of Boscalid and fluazinam, and proportioning is 50: 1-1: in the time of between 50, co-toxicity coefficient all more than 133.5, has synergistic effect; Proportioning is 20: 1-1: in the time of between 20, co-toxicity coefficient all is higher than 178.6, and synergistic effect is more obvious.
Biologicall test example 2: a kind of composite Toxicity Determination in cyanogen frost azoles (A) and Prochloraz, cyprodinil, the fluazinam (B) to powdery mildew of cucumber
Subjects: powdery mildew of cucumber (Erysiphe cichoracearum DC.)
Pot-culture method is adopted in this test.Sowing sense powdery mildew of cucumber kind potted plantly grows to 2-4 leaf periods, numbers standby.On the basis of preliminary experiment,, 5-7 series mass concentration is set according to the medicament activity.Soup is evenly sprayed in the blade face to all wetting, treat that the soup natural air drying is standby.Every processing 4 basins, and establish the processing that only contains solvent and surfactant and do not contain effective composition and make blank.24h behind the medicine, spray inoculation powdery mildew spore suspension.The process for preparation of spore suspension is as follows: with the pure water that is added with a small amount of Tween-80, draw the fresh spore that covers with on the white powder germ cucumber leaves, making spore concentration is 1 * 10
5Individual/the mL spore suspension.After in the greenhouse, cultivating 7d, add up the lesion area on every strain cucumber seedling blade, calculate disease index and control efficiency.
The powdery mildew of cucumber grade scale
0 grade: anosis;
1 grade: the sorus area accounts for below 5% of one-piece blade area;
3 grades: the sorus area accounts for the 6%-10% of one-piece blade area;
5 grades: the sorus area accounts for the 11%-20% of one-piece blade area;
7 grades: the sorus area accounts for the 21%-50% of one-piece blade area;
9 grades: the sorus area accounts for more than 50% of one-piece blade area.
The drug effect computational methods:
Control efficiency is converted into probability value (y), and liquor strength (μ g/ml) converts logarithm value (x) to, calculates concentration EC in virulence equation and the inhibition with method of least squares
50, toxicity index and co-toxicity coefficient calculate with analytical method the same.
Toxicity test result referring to table 4 to table 6
The serial proportioning of table 4 Boscalid and cyprodinil is to the pot experiment measurement result of powdery mildew of cucumber
| Handle | ??EC 50(μg/mL) | ??ATI | ??TTI | Co-toxicity coefficient CTC |
| Boscalid | ??12.21 | ??100 | ??/ | ??/ |
| Cyprodinil | ??14.36 | ??85.0 | ??/ | ??/ |
| Boscalid 50: cyprodinil 1 | ??8.93 | ??136.7 | ??99.7 | ??137.1 |
| Boscalid 20: cyprodinil 1 | ??7.12 | ??171.5 | ??99.3 | ??172.7 |
| Boscalid 10: cyprodinil 1 | ??6.28 | ??194.4 | ??98.6 | ??197.1 |
| Boscalid 5: cyprodinil 1 | ??5.04 | ??242.3 | ??97.5 | ??248.5 |
| Boscalid 1: cyprodinil 1 | ??4.19 | ??291.4 | ??92.5 | ??315.0 |
| Boscalid 1: cyprodinil 5 | ??5.02 | ??243.2 | ??87.5 | ??277.9 |
| Boscalid 1: cyprodinil 10 | ??6.81 | ??179.3 | ??86.4 | ??207.5 |
| Boscalid 1: cyprodinil 20 | ??7.96 | ??153.4 | ??85.7 | ??178.9 |
| Boscalid 1: cyprodinil 50 | ??10.35 | ??118.0 | ??85.3 | ??138.3 |
Result of the test shows, the composite powdery mildew of cucumber of preventing and treating of Boscalid and cyprodinil, and proportioning is 50: 1-1: in the time of between 50, co-toxicity coefficient all more than 137.1, has synergistic effect; Proportioning is 20: 1-1: in the time of between 20, co-toxicity coefficient all is higher than 172.7, and synergistic effect is more obvious.
The serial proportioning of table 5 Boscalid and fluazinam is to the pot experiment measurement result of powdery mildew of cucumber
| Handle | ??EC 50(μg/mL) | ??ATI | ??TTI | Co-toxicity coefficient CTC |
| Boscalid | ??12.21 | ??100 | ??/ | ??/ |
| Fluazinam | ??8.36 | ??146.1 | ??/ | ??/ |
| Boscalid 50: fluazinam 1 | ??8.93 | ??136.7 | ??100.9 | ??135.5 |
| Boscalid 20: fluazinam 1 | ??6.82 | ??179.0 | ??102.2 | ??175.2 |
| Boscalid 10: fluazinam 1 | ??6.08 | ??200.8 | ??104.2 | ??192.8 |
| Boscalid 5: fluazinam 1 | ??5.04 | ??242.3 | ??107.7 | ??225.0 |
| Boscalid 1: fluazinam 1 | ??3.19 | ??382.8 | ??123.0 | ??311.1 |
| Boscalid 1: fluazinam 5 | ??4.02 | ??303.7 | ??138.4 | ??219.5 |
| Boscalid 1: fluazinam 10 | ??4.61 | ??264.9 | ??141.9 | ??186.7 |
| Boscalid 1: fluazinam 20 | ??4.86 | ??251.2 | ??143.9 | ??174.6 |
| Boscalid 1: fluazinam 50 | ??6.35 | ??192.3 | ??145.1 | ??132.5 |
Result of the test shows, the composite powdery mildew of cucumber of preventing and treating of Boscalid and fluazinam, and proportioning is 50: 1-1: in the time of between 50, co-toxicity coefficient all more than 132.5, has synergistic effect; Proportioning is 20: 1-1: in the time of between 20, co-toxicity coefficient all is higher than 174.6, and synergistic effect is more obvious.
The serial proportioning of table 6 Boscalid and Prochloraz is to the pot experiment measurement result of powdery mildew of cucumber
| Handle | ??EC 50(μg/mL) | ??ATI | ??TTI | Co-toxicity coefficient CTC |
| Boscalid | ??12.21 | ??100 | ??/ | ??/ |
| Prochloraz | ??18.36 | ??66.5 | ??/ | ??/ |
| Boscalid 50: Prochloraz 1 | ??9.13 | ??133.7 | ??99.3 | ??134.6 |
| Boscalid 20: Prochloraz 1 | ??6.92 | ??176.4 | ??98.4 | ??179.3 |
| Boscalid 10: Prochloraz 1 | ??6.38 | ??191.4 | ??97.0 | ??197.4 |
| Boscalid 5: Prochloraz 1 | ??6.04 | ??202.2 | ??94.4 | ??214.1 |
| Boscalid 1: Prochloraz 1 | ??5.79 | ??210.9 | ??83.3 | ??253.3 |
| Boscalid 1: Prochloraz 5 | ??5.82 | ??209.8 | ??72.1 | ??291.0 |
| Boscalid 1: Prochloraz 10 | ??7.91 | ??154.4 | ??69.5 | ??221.9 |
| Boscalid 1: Prochloraz 20 | ??9.96 | ??122.6 | ??68.1 | ??180.0 |
| Boscalid 1: Prochloraz 50 | ??12.81 | ??95.3 | ??67.2 | ??141.9 |
Result of the test shows, the composite powdery mildew of cucumber of preventing and treating of Boscalid and Prochloraz, and proportioning is 50: 1-1: in the time of between 50, co-toxicity coefficient all more than 134.6, has synergistic effect; Proportioning is 20: 1-1: in the time of between 20, co-toxicity coefficient all is higher than 179.3, and synergistic effect is more obvious.
Above measurement result shows, proportioning a kind of in Boscalid (A) and Prochloraz, cyprodinil, the fluazinam (B) is 50: 1-1: in the time of between 50, have synergistic effect, 20: 1-1: in the time of between 20, co-toxicity coefficient is more than 172.7, and synergistic effect is more obvious.
Bactericidal composition of the present invention can be prepared into known method and be fit to wetting powder, suspending agent, water dispersible granules, missible oil, aqueous emulsion, the microemulsion that agricultural is used.Below describe with specific embodiment, percentage is mass percent in the prescription.A kind of in active component present specification middle finger Boscalid (A) and Prochloraz, cyprodinil, the fluazinam (B), below repeat no more.
Embodiment 1:10.2% Boscalid Prochloraz missible oil
Boscalid 10%
Prochloraz 0.2%
N-Methyl pyrrolidone (solvent) 10%
DMF (solvent) 10%
The newborn 1601# of farming (emulsifier) 5%
The newborn 500# of farming (emulsifier) 5%
Dimethylbenzene (solvent) complements to 100%.
Active component, solvent, emulsifier are added in the mixing kettle successively in the ratio of prescription, stir, make 10.2% Boscalid Prochloraz missible oil.
This embodiment is applied to prevent and treat grey mould fruit rot of strawberry.10.2% Boscalid Prochloraz missible oil is sprayed by 500 times of (Boscalid valid density is 200 μ g/ml, and Prochloraz valid density is 4 μ g/ml) thin ups, and the control efficiency of 7 days and 15 days is respectively 93.8%, 92.2% behind the medicine.25% Boscalid suspending agent by 1000 times (Boscalid valid density is 250 μ g/ml) and 25% Prochloraz missible oil by 1000 times (valid density is 250 μ g/ml), with using with quadrat method, the preventive effect of 7 days and 15 days is respectively 86.1%, 85.3% and 87.4%, 80.1% behind the medicine.The synergistic effect of the composite back of Boscalid and Prochloraz is obvious, to the preventive effect of grey mould fruit rot of strawberry significantly better than single agent.
Embodiment 2:5% Boscalid cyprodinil microemulsion
Boscalid 2.5%
Cyprodinil 2.5%
N-Methyl pyrrolidone (solvent) 10%
Isopropyl alcohol (cosolvent) 10%
The newborn 500# of farming (emulsifier) 5%
The newborn 1601# of farming (emulsifier) 5%
Water complements to 100%.
Former medicine, solvent, cosolvent, emulsifier are added together, make and be dissolved into even oil phase; With water-soluble component and the mixed water that gets of water; Under high-speed stirred, oil phase is mixed with water, make 5% Boscalid cyprodinil microemulsion.
This embodiment is applied to prevent and treat grape grey mould.5% Boscalid cyprodinil microemulsion is sprayed by 200 times of (Boscalid valid density is 125 μ g/ml, and cyprodinil valid density is 125 μ g/ml) thin ups, and the control efficiency of 7 days and 15 days is respectively 98.3%, 97.5% behind the medicine.25% Boscalid suspending agent by 1000 times (valid density is 250 μ g/ml) and 25% cyprodinil wetting powder by 1000 times (valid density is 250 μ g/ml), with using with quadrat method, the preventive effect of 7 days and 15 days is respectively 85.3%, 84.9% and 84.1%, 83.4% behind the medicine.The synergistic effect of the composite back of Boscalid and cyprodinil is obvious, to the preventive effect of grape grey mould significantly better than single agent.
Embodiment 3:30.6% Boscalid fluazinam wetting powder
Boscalid 0.6%
Fluazinam 30%
Lauryl sodium sulfate (wetting agent) 2%
Sodium lignin sulfonate (dispersant) 5%
Naphthalene sulfonate (dispersant) 3%
Kaolin (filler) complements to 100%.
Active component, various auxiliary agent and filler etc. are fully mixed in the ratio of prescription, after ultrafine crusher is pulverized, promptly get 30.6% Boscalid fluazinam wetting powder.
This embodiment is applied to gray mold of cucumber.30.6% Boscalid fluazinam is sprayed by 1500 times of (Boscalid valid density is 4 μ g/ml, and fluazinam valid density is 200 μ g/ml) thin ups, and the control efficiency of 7 days and 15 days is respectively 95.1%, 94.3% behind the medicine.20% Boscalid suspending agent by 1000 times (valid density is 200 μ g/ml) and 25% fluazinam wetting powder by 1000 times (valid density is 250 μ g/ml), with using with quadrat method, the preventive effect of 7 days and 15 days is respectively 85.3%, 84.4% and 89.3%, 88.4% behind the medicine.The synergistic effect of the composite back of Boscalid and fluazinam is obvious, to the preventive effect of gray mold of cucumber significantly better than single agent.
Embodiment 4:20% Boscalid prochloraz aqueous emulsion
Boscalid 5%
Prochloraz 15%
N-Methyl pyrrolidone (solvent) 10%
Calcium dodecyl benzene sulfonate (emulsifier) 5%
The newborn 600# of farming (emulsifier) 5%
Water complements to 100%
Active component, solvent, emulsifier are added together, make and be dissolved into even oil phase; Oil phase is added in the entry, under high-speed stirred, oil phase is mixed with water, make 20% Boscalid prochloraz aqueous emulsion.
This embodiment is applied to graw mold of tomato.20% Boscalid prochloraz aqueous emulsion is sprayed by 1000 times of (Boscalid valid density is 50 μ g/ml, and Prochloraz valid density is 150 μ g/ml) thin ups, and the control efficiency of 7 days and 15 days is respectively 93.6%, 92.4% behind the medicine.15% Boscalid suspending agent by 1000 times (valid density is 150 μ g/ml) and 25% Prochloraz wetting powder by 1000 times (valid density is 250 μ g/ml), with using with quadrat method, the preventive effect of 7 days and 15 days is respectively 84.1%, 82.3% and 87.3%, 80.5% behind the medicine.The synergistic effect of the composite back of Boscalid and Prochloraz is obvious, to the preventive effect of graw mold of tomato significantly better than single agent.
Embodiment 5:80% Boscalid cyprodinil water dispersible granules
Boscalid 40%
Cyprodinil 40%
Negel (dispersant) 2%
Sodium lignin sulfonate (dispersant) 1%
Lauryl sodium sulfate (wetting agent) 2%
Kaolin (filler) is to 100%
Active component, dispersant, wetting agent and the filler ratio in prescription is mixed, become wetting powder, add a certain amount of water mixing extruding again and make material through comminution by gas stream.Obtain 80% Boscalid cyprodinil water dispersible granules after the drying screening.
This embodiment is applied to prevent and treat powdery mildew of cucumber.With 4000 times of 80% Boscalid cyprodinil water dispersible granules (Boscalid valid density is 100 μ g/ml, and cyprodinil valid density is 100 μ g/ml) thin up spraying, the control efficiency of 7 days and 15 days is respectively 98.3%, 97.5% behind the medicine.40% Boscalid water dispersible granules is by 2000 times (valid density is 200 μ g/ml), 40% cyprodinil water dispersible granules is by 2000 times (valid density is 200 μ g/ml), with using with quadrat method, the preventive effect of 7 days and 15 days is respectively 85.2%, 84.2% and 83.4%, 82.3% behind the medicine.The synergistic effect of the composite back of Boscalid and cyprodinil is obvious, to the preventive effect of powdery mildew of cucumber significantly better than single agent.
Embodiment 6:20% Boscalid fluazinam suspending agent
Boscalid 10%
Fluazinam 10%
Methyl naphthalene sulfonate formaldehyde condensate (dispersant) 10%
Xanthans (thickener) 1%
Bentonite (carrier) 1%
Glycerine (antifreeze) 1%
Water complements to 100%.
The ratio of each component such as active component, dispersant, thickener, carrier and water in prescription mixed, after grinding and/or high speed shear, obtain 20% Boscalid fluazinam suspending agent.
This embodiment is applied to prevent and treat wheat powdery mildew.20% Boscalid fluazinam suspending agent is sprayed by 1000 times of (Boscalid valid density is 100 μ g/ml, and fluazinam valid density is 100 μ g/ml) thin ups, and the control efficiency of 7 days and 15 days is respectively 98.3%, 97.6% behind the medicine.20% Boscalid suspending agent by 1000 times (valid density is 200 μ g/ml) and 20% fluazinam wetting powder by 1000 times (valid density is 200 μ g/ml), with using with quadrat method, the preventive effect of 7 days and 15 days is respectively 85.2%, 84.3% and 88.4%, 87.7% behind the medicine.The synergistic effect of the composite back of Boscalid and fluazinam is obvious, to the preventive effect of wheat powdery mildew significantly better than single agent.
Embodiment 7:20% Boscalid prochloraz aqueous emulsion
Boscalid 5%
Prochloraz 15%
Lauryl sodium sulfate (wetting agent) 2%
Sodium lignin sulfonate (dispersant) 5%
Naphthalene sulfonate (dispersant) 3%
Kaolin (filler) complements to 100%.
Active component, various auxiliary agent and filler etc. are fully mixed in the ratio of prescription, after ultrafine crusher is pulverized, promptly get 30.6% Boscalid Prochloraz wetting powder.
This embodiment is applied to grape powdery mildew.20% Boscalid Prochloraz wetting powder is sprayed by 1000 times of (Boscalid valid density is 50 μ g/ml, and Prochloraz valid density is 150 μ g/ml) thin ups, and the control efficiency of 7 days and 15 days is respectively 92.6%, 90.4% behind the medicine.10% Boscalid suspending agent by 1000 times (valid density is 100 μ g/ml) and 20% Prochloraz wetting powder by 1000 times (valid density is 200 μ g/ml), with using with quadrat method, the preventive effect of 7 days and 15 days is respectively 82.7%, 80.4% and 86.3%, 78.5% behind the medicine.The synergistic effect of the composite back of Boscalid and Prochloraz is obvious, to the preventive effect of grape powdery mildew significantly better than single agent.
Claims (7)
1, a kind of bactericidal composition is characterized in that: contain in the described bactericidal composition a kind of (B) in active ingredient Boscalid (A) and Prochloraz, cyprodinil or the fluazinam, mass ratio (A) and (B) is 50: 1-1: 50.
2, according to claim 1, it is characterized in that: active ingredient (A) and mass ratio (B) are 20: 1-1: 20.
3, according to claim 1 or 2, it is characterized in that: the gross mass percentage composition of active ingredient in bactericidal composition is 5%-80%.
4, according to claim 3, it is characterized in that: the formulation of described bactericidal composition is missible oil, microemulsion, aqueous emulsion, wetting powder, suspending agent or water dispersible granules.
5, bactericidal composition according to claim 1 is characterized in that: described bactericidal composition is applied to prevent and treat the crop fungal disease.
6, bactericidal composition according to claim 1 is characterized in that: described bactericidal composition is applied to prevent and treat powdery mildew and gray mold.
7, the application of bactericidal composition according to claim 5 is characterized in that: described crop is flowers, wheat, fruit tree, cotton, rape, vegetables etc.
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| CN200910161261A CN101653139A (en) | 2009-07-22 | 2009-07-22 | Compound bactericidal composition containing boscalid |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102308807A (en) * | 2011-08-11 | 2012-01-11 | 青岛凯源祥化工有限公司 | Germicide composition containing tetraconazole and boscalid |
| WO2012165266A1 (en) * | 2011-05-27 | 2012-12-06 | Ishihara Sangyo Kaisha, Ltd. | Method for controlling plant diseases |
| CN103053529A (en) * | 2012-12-29 | 2013-04-24 | 广东中迅农科股份有限公司 | Carvacrol-fluazinam pesticide composition |
| CN103380777A (en) * | 2012-05-04 | 2013-11-06 | 陕西韦尔奇作物保护有限公司 | Sterilizing composition containing tiadinil |
| CN104351185A (en) * | 2014-11-25 | 2015-02-18 | 南京农业大学 | Composition containing fluazinam and boscalid |
| CN106135252A (en) * | 2015-04-13 | 2016-11-23 | 南京华洲药业有限公司 | A kind of containing Boscalid and the bactericidal composition of prochloraz-manganese chloride complex and application |
| CN106614601A (en) * | 2016-12-08 | 2017-05-10 | 山西奇星农药有限公司 | Pesticide for preventing and treating gray mold of crop and preparation method of pesticide |
| CN114128718A (en) * | 2021-11-09 | 2022-03-04 | 黑龙江八一农垦大学 | Pharmaceutical composition for preventing and treating sunflower sclerotinia rot |
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2009
- 2009-07-22 CN CN200910161261A patent/CN101653139A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012165266A1 (en) * | 2011-05-27 | 2012-12-06 | Ishihara Sangyo Kaisha, Ltd. | Method for controlling plant diseases |
| CN102308807A (en) * | 2011-08-11 | 2012-01-11 | 青岛凯源祥化工有限公司 | Germicide composition containing tetraconazole and boscalid |
| CN103380777A (en) * | 2012-05-04 | 2013-11-06 | 陕西韦尔奇作物保护有限公司 | Sterilizing composition containing tiadinil |
| CN103053529A (en) * | 2012-12-29 | 2013-04-24 | 广东中迅农科股份有限公司 | Carvacrol-fluazinam pesticide composition |
| CN103053529B (en) * | 2012-12-29 | 2014-12-31 | 广东中迅农科股份有限公司 | Carvacrol-fluazinam pesticide composition |
| CN104351185A (en) * | 2014-11-25 | 2015-02-18 | 南京农业大学 | Composition containing fluazinam and boscalid |
| CN106135252A (en) * | 2015-04-13 | 2016-11-23 | 南京华洲药业有限公司 | A kind of containing Boscalid and the bactericidal composition of prochloraz-manganese chloride complex and application |
| CN106614601A (en) * | 2016-12-08 | 2017-05-10 | 山西奇星农药有限公司 | Pesticide for preventing and treating gray mold of crop and preparation method of pesticide |
| CN106614601B (en) * | 2016-12-08 | 2019-04-12 | 山西奇星农药有限公司 | It is a kind of for preventing and treating the pesticide and preparation method thereof of crops gray mold |
| CN114128718A (en) * | 2021-11-09 | 2022-03-04 | 黑龙江八一农垦大学 | Pharmaceutical composition for preventing and treating sunflower sclerotinia rot |
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Application publication date: 20100224 |