CN101548677B - Sterilizing compound of ethirimol and triazole - Google Patents
Sterilizing compound of ethirimol and triazole Download PDFInfo
- Publication number
- CN101548677B CN101548677B CN2009100224618A CN200910022461A CN101548677B CN 101548677 B CN101548677 B CN 101548677B CN 2009100224618 A CN2009100224618 A CN 2009100224618A CN 200910022461 A CN200910022461 A CN 200910022461A CN 101548677 B CN101548677 B CN 101548677B
- Authority
- CN
- China
- Prior art keywords
- phonetic phenol
- difenoconazole
- powdery mildew
- tebuconazole
- triazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The invention relates to a sterilizing compound of ethirimol and triazole, and the compound contains the ethirimol of synergic and effective amount, the triazole bactericide which is tebuconazole, difenoconazole, hexaconazole or myclobutanil, and diluent or carrier that is acceptable in pesticide, wherein the weight ratio of the ethirimol to the triazole bactericide which is tebuconazole, difenoconazole, hexaconazole or myclobutanil is 25:1 to 1:50. When being compounded with the triazole bactericide, the ethirimol has obvious synergy, and the amount of effective ingredients of the compound preparation is less than that when being used independently. The compound can be used for curing powdery mildew of fruit trees, melons, beans, solanaceous fruits, flowers, and the like.
Description
Technical field
The present invention relates to a kind of composition pesticide, particularly contain the composition of phonetic phenol of second and triazole bactericidal agent.
Background technology
Crop is subjected to infecting of various diseases, particularly fungal disease easily in growth and development process, it is of a great variety, and harm is serious.For a long time, chemical control is the main effective means of preventing and treating disease.Yet, in recent years because single drug and the medication of non-science have caused many kinds of pathogens that the agricultural chemicals of current use has been produced resistance.Powdery mildew is to take place on many important crops generally, endanger seriously, difficult a kind of worldwide disease of preventing and treating.Ascomycotina powdery mildew purpose fungi all can cause powdery mildew, and the pathogen kind is a lot.Such germ all can sprout to 10-30 ℃ of conidium in temperature, and is not high to humidity requirement, and normal condition can be finished and once infect circulation in following 10 days; Therefore caused season of growth of crop repeated multiple times to be infected, in case take place to cause irremediable massive losses to agricultural production under characteristics, especially the plastic greenhouse planting environment of very fast outbreak of epidemic.
Current, domestic single agent of registering on powdery mildew has 26 kinds such as triadimefon, kresoxim-methyl, Flusilazole, Difenoconazole, nitrile bacterium azoles, and composite kind has 109.The history that the continual renovation that the continuous release explanation controlling powdery mildew history of these medicaments is medicaments is regenerated, resistance development makes many outstanding bactericide forfeiture using values soon.Domestic controlling powdery mildew medicament has roughly experienced following three phases:
Phase I: with inorganic sulfurs such as sulphur, lime sulfur, thiophanate methyl, mancozeb and other wide-spectrum bactericide is representative, and big to the powdery mildew consumption, preventive effect is substantially about 60%; Such medicament does not almost have result of treatment to powdery mildew, is mainly used in the premorbid protection, and sulphur preparation can not use many vegetable melon and fruit sensitivities simultaneously.
Second stage: with triazolone (triadimefon), nitrile bacterium azoles, alkene azoles alcohol, Difenoconazole, Flusilazole etc. is the triazole germicide series of representative, improves a lot than the activity of first generation bactericide to powdery mildew.But this compounds is single to the germ action site.Germ has cross resistance to such medicament.This compounds has excitant to plant simultaneously, and consumption will suppress plant growing slightly greatly, reduces output.Such pharmacy control efficacy is substantially at 70-80%, and effect is general.
Phase III: with the import kresoxim-methyl is the noval chemical compound kind of representative, mechanism of action uniqueness, action site is more, to powdery mildew specially higher, the effect of the property controlled can reach more than 90%; But because domestic long-term in recent years use has continuously produced obvious pesticide resistance, and effect descends to some extent, the reagent cost of import simultaneously is too high.Concerning Chinese farmers, be difficult to accept.Therefore, for overcoming the pesticide resistance of germ, be badly in need of the bactericide new varieties of efficient, low toxicity, safety, environmental protection.
The phonetic phenol of second (bupirimate) is a kind of miazines bactericide, and systemic fungicide absorbs by blade and root, is mainly used in the powdery mildew of control crop, and the diseases such as leaf spot of the rust of beans, red spot, banana are all had good control efficiency.Salmonella reversion test, mouse marrow cell micro nuclear test, three mutagenicity tests of mouse testis cell chromosome aberration test are all negative, do not see mutagenesis, belong to the low toxicity product.But its unit are consumption is big, and use cost is too high, has limited the popularization of certain limit.
Tebuconazole (tebuconazole) belongs to triazole bactericidal agent, is to stay pure demethylation inhibitor, is to be used for the seed treatment of important economic crops or the efficient systemic fungicide of foliage spray.Can prevent and treat multiple rust, powdery mildew, net blotch, root rot, head blight, the smut of cereal crop effectively and plant and pass zonate spot, tea tree tea gall, sigatoka etc.But, Tebuconazole use cost height is general to the powdery mildew preventive effect.
Difenoconazole (difenoconazole) belongs to triazole bactericidal agent, and fungicidal spectrum is wide, and leaf surface treatment or seed treatment can improve output and the guaranteed quality of crop.To Ascomycetes, Basidiomycetes and comprise Alternaria, Ascochyta, the mould genus of tail spore, Colletotrichum, ball Cuo Pseudomonas, Phoma, Ramularia, Septoria, Venturia partly know disease, Erysiphaceae, Uredinales and some are planted and are passed pathogen lasting protection and therapeutic action are arranged.Also fine to bitter rot or anthracnose of grape, white rot effect, but this compounds has excitant to plant, and consumption will suppress plant growing slightly greatly, reduces output.
Own azoles alcohol (hexaconazole) belongs to triazole bactericidal agent, is to stay pure demethylation inhibitor, and the disease that fungi especially Basidiomycota and Ascomycota are caused has the protection and the therapeutic action of broad spectrum activity.To powdery mildew, scab, banded sclerotial blight, fungi especially basidiomycetes and the microbial disease of ascus there are the protection and the therapeutic action of broad spectrum activity.Be mainly used in the powdery mildew of cucumber etc.But the drug cost height is difficult to large tracts of land and promotes.
Nitrile bacterium azoles (myclobutanil) is an ergosterol biosynthesis inhibitor, is the systemic fungicide with protection and therapeutic action.Characteristics such as it has efficiently, wide spectrum, low toxicity, to crop safety, the lasting period is long, and Ascomycotina, Basidiomycotina, the microbial multiple diseases of Deuteromycotina cause of disease are had good preventing and result of treatment; Powdery mildew, rust, the smut that can be widely used in wheat, the scab of pears, apple, powdery mildew, brown spot, graywall, melon powdery mildew, the leaf spot of banana and peanut, the powdery mildew of grape, the powdery mildew of vegetables and flowers, rust etc.But nitrile bacterium azoles is owing to use for many years, and single use preventive effect obviously descends, and simultaneously, also is faced with the pesticide resistance problem.
Summary of the invention
The purpose of this invention is to provide a kind of efficient, low toxicity, environmental protection and help the Fungicidal composition of germ resistance management, said composition make full use of two kinds of active components be mixed the synergistic effect that produced, improve preventive effect and delay the drug-fast generation speed of germ, the disease that is used to prevent and treat crops such as wheat, fruit tree, vegetables.
Implementation procedure of the present invention is as follows:
A kind of bactericidal composition, the phonetic phenol of second and triazole bactericidal agent Tebuconazole, Difenoconazole, own azoles alcohol or the nitrile bacterium azoles that contain the synergy effective dose, and acceptable diluent or carrier on the agricultural chemicals, wherein the mass ratio of phonetic phenol of second and triazole bactericidal agent is 20: 1～1: 50, preferred mass ratio is 25: 1～1: 25, and all the other are to allow in the agricultural chemicals to use and the acceptable auxiliary element.
Fungicidal composition of the present invention is prepared into known method and is fit to any one formulation that agricultural is used, and reasonable formulation is wetting powder, water dispersible granules, suspending agent and aqueous emulsion, and the total content of active ingredient is 5%-80% in the preparation.
The auxiliary agent that uses in the composition of the present invention comprises that solvent, dispersant, emulsifier, stabilizing agent, antifreezing agent, thickener etc. and other are of value to the known substance that active ingredient is stablized and drug effect is brought into play in preparation, all be the various compositions of using or allow use in the pesticidal preparations always, be not particularly limited, concrete composition and consumption require to determine by simple experiment according to prescription.
Product described in the invention can the finished product preparation form provide, and promptly each material mixes in the composition, and the composition of composition also can provide with single agent form, directly directly mixes in bucket or jar before the use, is diluted to required concentration then.The frequency of administration of the present composition and amount of application change with weather condition and crop state, can reach the purpose of control by using suitable formulation.
Fungicidal composition of the present invention can be used for preventing and treating the various agricultural disease, be mainly used in the controlling powdery mildew of crops such as wheat, vegetables, fruit tree, especially wheat powdery mildew, powdery mildew of cucumber, grape powdery mildew, apple mildew, beans powdery mildew, flowers powdery mildew, mango powdery mildew etc. have good control efficiency.
Compared with prior art, beneficial effect of the present invention is: 1, being mixed has obvious synergistic effect, has improved control efficiency; 2, enlarged the control spectrum; 3, two kinds of active ingredients are mixed, and have reduced dosage, thereby have reduced cost and the pollution that has alleviated environment; 4, be mixed and delayed the resistance of single active ingredient.
Embodiment
In order to make purpose of the present invention, technical scheme and advantage clearer, the present invention describes with following specific embodiment, but the present invention is limited to these examples absolutely not.The following stated only is the present invention embodiment preferably, only in order to explain the present invention, can not therefore be interpreted as the restriction to claim of the present invention.Should be pointed out that all any modifications of being made within the spirit and principles in the present invention, be equal to replacement and improvement etc., all should be included within protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
The combination of active principles of different agricultural chemicals is made agricultural chemicals, is a kind of mode effectively and efficiently that exploitation at present and development novel pesticide and control agricultural go up the resistance germ.The agricultural chemicals of different cultivars shows three kinds of type of action: summation action, synergistic effect and antagonism after mixing usually.But be specially which kind of effect, unpredictable, have only by a large amount of tests and just can know.Compound synergic is well filled a prescription, owing to obviously improved actual control efficiency, reduced the usage amount of agricultural chemicals, thereby delayed the drug-fast generation speed of germ widely, and be the important means of integrated control disease.
The inventor is by a large amount of screening tests, the abundant method of utilization Sun Yun is carried out the synergistic effect analysis of different proportionings to phonetic phenol of second and triazole bactericide composition, discovery is in certain ratio range, phonetic phenol of second and triazole bactericidal agent combination antagonism white powder germ have obvious role in synergism, and be not only the simple addition of two kinds of medicaments, specifically be illustrated with following biologicall test example.
Biologicall test example 1: phonetic phenol of second and Tebuconazole composite Toxicity Determination and proportioning screening to wheat powdery mildew
Adopt spray-on process, measure the phonetic phenol of second and the composite indoor virulence of Tebuconazole of different proportion wheat powdery mildew.
Calculate the toxicity index of each medicament and the co-toxicity coefficient of mixture (CTC value) according to the abundant method of Sun Yun, promptly CTC≤80 are antagonism, and 80＜CTC＜120 are summation action, and CTC 〉=120 are synergistic effect.
Actual measurement toxicity index (ATI)=standard medicament EC
50/ reagent agent EC
50* 100
The percentage composition of B in percentage composition+B medicament toxicity index * mixture of A in theoretical toxicity index (TTI)=A medicament toxicity index * mixture
Co-toxicity coefficient (CTC)=mixture actual measurement toxicity index (the ATI)/theoretical toxicity index (TTI) * 100 of mixture
The result shows that phonetic phenol of second and Tebuconazole are between proportioning 25: 1～1: 50, particularly 20: 1-1: between 20, obvious synergistic effect is arranged, co-toxicity coefficient is at (table 1) more than 120.
The composite indoor co-toxicity coefficient measurement result of phonetic phenol of table 1 second and Tebuconazole to wheat powdery mildew
Biologicall test example 2: phonetic phenol of second and Difenoconazole composite Toxicity Determination and proportioning screening to apple mildew
Adopt spray-on process, measure the phonetic phenol of second and the composite indoor virulence of Difenoconazole of different proportion apple mildew.The result shows that phonetic phenol of second and the composite proportioning of Difenoconazole are between 25: 1～1: 50, particularly 20: 1-1: between 20, show obvious synergistic effect, co-toxicity coefficient is at (table 2) more than 125.
The composite indoor co-toxicity coefficient measurement result of phonetic phenol of table 2 second and Difenoconazole to apple mildew
| Handle | EC 50(μg/ml) | AT1 | TTI | Co-toxicity coefficient CTC |
| The phonetic phenol of second | 22.65 | 100 | ||
| Difenoconazole | 8.07 | 280.67 | ||
| The phonetic phenol 20 of second: Difenoconazole 1 | 15.65 | 144.73 | 108.60 | 133.26 |
| The phonetic phenol 12 of second: Difenoconazole 1 | 14.17 | 159.84 | 113.90 | 140.34 |
| The phonetic phenol 8 of second: Difenoconazole 1 | 11.69 | 193.76 | 120.07 | 161.36 |
| The phonetic phenol 3 of second: Difenoconazole 1 | 7.43 | 304.85 | 145.17 | 210.00 |
| The phonetic phenol 1 of second: Difenoconazole 1 | 7.29 | 310.70 | 190.33 | 163.24 |
| The phonetic phenol 1 of second: Difenoconazole 6 | 6.38 | 355.02 | 254.86 | 139.30 |
| The phonetic phenol 1 of second: Difenoconazole 10 | 6.24 | 362.98 | 264.24 | 137.37 |
| The phonetic phenol 1 of second: Difenoconazole 20 | 6.58 | 344.22 | 272.07 | 126.52 |
Biologicall test example 3: phonetic phenol of second and own azoles alcohol composite Toxicity Determination and proportioning screening to grape powdery mildew
Adopt spray-on process, the phonetic phenol of second of mensuration different proportion and own azoles alcohol compound drug are to the indoor virulence of grape powdery mildew.The result shows that phonetic phenol of second and own azoles alcohol are between proportioning 25: 1～1: 50, particularly 25: 1-1: between 25, obvious synergistic effect is arranged, co-toxicity coefficient is at (table 3) more than 120.
Phonetic phenol of table 3 second and the composite indoor co-toxicity coefficient measurement result of own azoles alcohol to grape powdery mildew
| Handle | ?EC 50(ug/mL) | ATI | TTI | Co-toxicity coefficient CTC |
| The phonetic phenol of second | 20.03 | 100 | ||
| Own azoles alcohol | 7.91 | 253.22 | ||
| The phonetic phenol 25 of second: own azoles alcohol 1 | 15.06 | 133.00 | 105.89 | 125.60 |
| The phonetic phenol 18 of second: own azoles alcohol 1 | 13.96 | 143.48 | 108.06 | 132.77 |
| The phonetic phenol 12 of second: own azoles alcohol 1 | 11.54 | 173.57 | 111.79 | 155.27 |
| The phonetic phenol 6 of second: own azoles alcohol 1 | 7.28 | 275.14 | 121.89 | 225.73 |
| The phonetic phenol 1 of second: own azoles alcohol 1 | 6.32 | 316.93 | 176.61 | 179.45 |
| The phonetic phenol 1 of second: own azoles alcohol 8 | 6.03 | 332.17 | 236.20 | 140.63 |
| The phonetic phenol 1 of second: own azoles alcohol 14 | 6.2 | 323.06 | 243.01 | 132.94 |
| The phonetic phenol 1 of second: own azoles alcohol 18 | 6.48 | 309.10 | 244.21 | 126.57 |
| The phonetic phenol 1 of second: own azoles alcohol 25 | 6.61 | 303.03 | 247.33 | 122.52 |
Biologicall test example 4: phonetic phenol of second and myclobutanil compositional are to Toxicity Determination and the proportioning screening of mango white powder germ
Adopt spray-on process, the phonetic phenol of second of mensuration different proportion and myclobutanil compositional medicament are to the indoor virulence of mango powdery mildew.Measurement result shows that phonetic phenol of second and nitrile bacterium azoles between 22: 1～1: 22, have obvious synergistic effect especially between proportioning 25: 1～1: 50, and co-toxicity coefficient is at (table 4) more than 120.
Phonetic phenol of table 4 second and myclobutanil compositional are to the indoor co-toxicity coefficient measurement result of mango powdery mildew
Fungicidal composition of the present invention can be prepared into known method and be fit to any one formulation that agricultural goes up use, and reasonable formulation is wetting powder, water dispersible granules, suspending agent and aqueous emulsion.Below describe with specific embodiment.Percentage all is weight percentage in all prescriptions.The processing technology of the various preparations of the present composition is prior art, can change to some extent according to different situations.
The phonetic phenol Tebuconazole of embodiment 1:40% wetting powder
The phonetic phenol 10% of second
Tebuconazole 30%
Lauryl sodium sulfate 2%
Sodium lignin sulfonate 5%
White carbon black 10%
Kaolin complements to 100%.
Active component, various auxiliary agent and filler etc. are fully mixed in the ratio of prescription, after ultrafine crusher is pulverized, promptly get the phonetic phenol Tebuconazole of 40% second wetting powder.
This embodiment is used to prevent and treat powdery mildew of cucumber.By 4000 extraordinarily water dilution sprayings, 7 days control efficiency is 90.3% behind the medicine with the phonetic phenol Tebuconazole of 40% second wetting powder.The phonetic phenol suspending agent of 25% second, is used with the quadrat method use by 2000 times by 1000 times and 25% tebuconazole aqueous emulsion, and 7 days preventive effect is respectively 82.3% and 85.8% behind the medicine.The synergistic effect of the composite back of phonetic phenol of second and Tebuconazole is obvious, to the preventive effect of powdery mildew of cucumber significantly better than single agent; Because pharmacy control efficacy improves, the amount ratio of compound drug active ingredient uses obviously separately and reduces, thereby has also alleviated the pollution to environment.
The phonetic phenol tebuconazole suspension concentrates of embodiment 2:20% second
The phonetic phenol 10% of second
Tebuconazole 10%
Methyl naphthalene sulfonate formaldehyde condensate 10%
Xanthans 1%
Bentonite 1%
Glycerine 5%
Water supplies 100%.
The ratio of each component such as active component, dispersant, wetting agent and water in prescription mixed, after grinding and/or high speed shear, obtain the phonetic phenol tebuconazole suspension concentrates of 20% second.
This embodiment is used to prevent and treat wheat powdery mildew.By 2500 extraordinarily water dilution sprayings, 7 days control efficiency is 91.2% behind the medicine with 20% phonetic phenol tebuconazole suspension concentrates.The phonetic phenol suspending agent of 25% second, is used with the quadrat method use by 2000 times by 1000 times and 25% tebuconazole aqueous emulsion, and 7 days preventive effect is respectively 84.4% and 78.5% behind the medicine.The synergistic effect of the composite back of phonetic phenol of second and Tebuconazole is obvious, and significantly better than single agent, and the consumption of active ingredient obviously reduces to the preventive effect of wheat powdery mildew.
The phonetic phenol Difenoconazole of embodiment 3:28% second aqueous emulsion
The phonetic phenol 24% of second
Difenoconazole 4%
N-Methyl pyrrolidone 10%
Calcium dodecyl benzene sulfonate 5%
The newborn 600# 5% of farming
Water complements to 100%.
Former medicine, solvent, emulsifier are added together, make and be dissolved into even oil phase; With water-soluble component and the mixed water that gets of water; Under high-speed stirred, oil phase is mixed with water, make the phonetic phenol Difenoconazole of 28% second aqueous emulsion.
This embodiment is used to prevent and treat apple mildew.By 3000 extraordinarily water dilution sprayings, 7 days control efficiency is 93.9% behind the medicine with the phonetic phenol Difenoconazole of 28% second aqueous emulsion.The phonetic phenol suspending agent of 25% second, is used with the quadrat method use by 1000 times by 1000 times and 10% Difenoconazole aqueous emulsion, and 7 days preventive effect is respectively 86.4% and 80.4% behind the medicine.The synergistic effect of the composite back of phonetic phenol of second and Difenoconazole is obvious, and significantly better than single agent, and the consumption of active ingredient obviously reduces to the preventive effect of apple mildew.
The phonetic phenol tebuconazole aqueous emulsion of embodiment 4:25% second
The phonetic phenol 23% of second
Tebuconazole 2%
N-Methyl pyrrolidone 10%
Calcium dodecyl benzene sulfonate 5%
The newborn 600# 5% of farming
Water complements to 100%.
Former medicine, solvent, emulsifier are added together, make and be dissolved into even oil phase; With water-soluble component and the mixed water that gets of water; Under high-speed stirred, oil phase is mixed with water, make the phonetic phenol tebuconazole aqueous emulsion of 25% second.
This embodiment is used to prevent and treat powdery mildew of cucumber.By 2500 extraordinarily water dilution sprayings, 7 days control efficiency is 91.7% behind the medicine with the phonetic phenol tebuconazole aqueous emulsion of 25% second.The phonetic phenol suspending agent of 25% second, is used with the quadrat method use by 2000 times by 1000 times and 25% tebuconazole aqueous emulsion, and 7 days preventive effect is respectively 85.9% and 86.8% behind the medicine.The synergistic effect of the composite back of phonetic phenol of second and Tebuconazole is obvious, to the preventive effect of powdery mildew of cucumber significantly better than single agent; Because pharmacy control efficacy improves, the amount ratio of compound drug active ingredient uses obviously separately and reduces, thereby has also alleviated the pollution to environment.
The phonetic phenol hexaconazole suspending agent of embodiment 5:35% second
The phonetic phenol 7% of second
Own azoles alcohol 28%
Methyl naphthalene sulfonate formaldehyde condensate 10%
Xanthans 1%
Bentonite 1%
Glycerine 5%
Water complements to 100%.
The ratio of each component such as active component, dispersant, wetting agent and water in prescription mixed, after grinding and/or high speed shear, obtain the phonetic phenol hexaconazole suspending agent of 35% second.
This embodiment is used to prevent and treat grape powdery mildew.By 4000 extraordinarily water dilution sprayings, 10 days control efficiency is 90.6% behind the medicine with the phonetic phenol hexaconazole suspending agent of 35% second.The phonetic phenol suspending agent of 25% second, is used with the quadrat method use by 1500 times by 1000 times and 10% hexaconazole suspending agent, and 10 days preventive effect is respectively 85.3% and 78.8% behind the medicine.The composite back synergistic effect of the phonetic phenol of second and own azoles alcohol is obvious, and significantly better than single agent, and the consumption of active ingredient obviously reduces to the preventive effect of grape powdery mildew.
The own azoles alcohol of the phonetic phenol of embodiment 6:45% second wetting powder
The phonetic phenol 5% of second
Own azoles alcohol 40%
Lauryl sodium sulfate 2%
Sodium lignin sulfonate 5%
White carbon black 10%
Kaolin complements to 100%.
Active component, various auxiliary agent and filler etc. are fully mixed in the ratio of prescription, after ultrafine crusher is pulverized, promptly get the own azoles alcohol of the phonetic phenol of 45% second wetting powder.
This embodiment is used to prevent and treat powdery mildew of cucumber.By 5000 extraordinarily water dilution sprayings, 7 days control efficiency is 92.6% behind the medicine with the phonetic phenol hexaconazole microemulsion of 45% second.The phonetic phenol suspending agent of 25% second, is used with the quadrat method use by 1500 times by 1000 times and 10% hexaconazole suspending agent, and 7 days preventive effect is respectively 79.4% and 84.5% behind the medicine.The composite back synergistic effect of the phonetic phenol of second and own azoles alcohol is obvious, and significantly better than single agent, and the consumption of active ingredient obviously reduces to the preventive effect of powdery mildew of cucumber.
The phonetic phenol Difenoconazole of embodiment 7:42% second wetting powder
The phonetic phenol 35% of second
Own azoles alcohol 7%
Lauryl sodium sulfate 2%
Sodium lignin sulfonate 5%
White carbon black 10%
Kaolin complements to 100%.
Active component, various auxiliary agent and filler etc. are fully mixed in the ratio of prescription, after ultrafine crusher is pulverized, promptly get the phonetic phenol Difenoconazole of 42% second wetting powder.
This embodiment is used to prevent and treat powdery mildew of strawberry.By 4500 extraordinarily water dilution sprayings, 10 days control efficiency is 92.6% behind the medicine with the phonetic phenol Difenoconazole of 42% second wetting powder.The phonetic phenol suspending agent of 25% second, is used with the quadrat method use by 1000 times by 1000 times and 10% Difenoconazole aqueous emulsion, and 10 days preventive effect is respectively 81.3% and 87.4% behind the medicine.The synergistic effect of the composite back of phonetic phenol of second and Difenoconazole is obvious, and significantly better than single agent, and the consumption of active ingredient obviously reduces to the preventive effect of powdery mildew of strawberry.
The phonetic phenol difenoconazole water dispersible granule of embodiment 8:55% second
The phonetic phenol 5% of second
Difenoconazole 50%
Negel 5%
Sodium lignin sulfonate 7%
Lauryl sodium sulfate 2%
Ammonium sulfate 5%
Precipitated calcium carbonate complements to 100%.
Active component, dispersant, wetting agent, disintegrant and the filler ratio in prescription is mixed, become wetting powder through comminution by gas stream, add a certain amount of water mixing extruding again and make material, obtain the phonetic phenol Difenoconazole of 55% second water-dispersible granules after the drying screening.
This embodiment is used to prevent and treat the beans powdery mildew.By 6000 extraordinarily water dilution sprayings, 10 days control efficiency is 90.7% behind the medicine with the phonetic phenol difenoconazole water dispersible granule of 55% second.The phonetic phenol suspending agent of 25% second, is used with the quadrat method use by 1000 times by 1000 times and 10% Difenoconazole, and 10 days preventive effect is respectively 71.2% and 84.1% behind the medicine.The synergistic effect of the composite back of phonetic phenol of second and Difenoconazole is obvious, to the preventive effect of beans powdery mildew significantly better than single agent; Because pharmacy control efficacy improves, the amount ratio of compound drug active ingredient uses obviously separately and reduces, thereby has also alleviated the pollution to environment.
The phonetic phenol diniconazole water dispersible granule of embodiment 9:70% second
The phonetic phenol 50% of second
Own azoles alcohol 20%
Negel 5%
Sodium lignin sulfonate 7%
Lauryl sodium sulfate 2%
Ammonium sulfate 5%
Precipitated calcium carbonate complements to 100%.
Active component, dispersant, wetting agent, disintegrant and the filler ratio in prescription is mixed, become wetting powder, add a certain amount of water mixing extruding again and make material, obtain the own azoles alcohol of the phonetic phenol of 70% second water-dispersible granules after the drying screening through comminution by gas stream.
This embodiment is used to prevent and treat the flowers powdery mildew.By 7000 extraordinarily water dilution sprayings, 7 days control efficiency is 95.8% behind the medicine with the own azoles alcohol of the phonetic phenol of 70% second water-dispersible granules.The phonetic phenol suspending agent of 25% second, is used with the quadrat method use by 1500 times by 1000 times and 10% hexaconazole suspending agent, and 7 days preventive effect is respectively 85.9% and 89.6% behind the medicine.The composite back synergistic effect of the phonetic phenol of second and own azoles alcohol is obvious, and significantly better than single agent, and the consumption of active ingredient reduces to the preventive effect of flowers powdery mildew.
The phonetic phenol nitrile of embodiment 9:52% second bacterium azoles water dispersible granules
The phonetic phenol 48% of second
Own azoles alcohol 4%
Negel 5%
Sodium lignin sulfonate 7%
Lauryl sodium sulfate 2%
Ammonium sulfate 5%
Precipitated calcium carbonate complements to 100%.
Active component, dispersant, wetting agent, disintegrant and the filler ratio in prescription is mixed, become wetting powder, add a certain amount of water mixing extruding again and make material, obtain the phonetic phenol nitrile of 52% second bacterium azoles water-dispersible granules after the drying screening through comminution by gas stream.
This embodiment is used to prevent and treat powdery mildew of cucumber.By 5000 extraordinarily water dilution sprayings, 7 days control efficiency is 95.8% behind the medicine with the phonetic phenol nitrile of 52% second bacterium azoles water-dispersible granules.The phonetic phenol suspending agent of 25% second, is used with the quadrat method use by 2000 times by 1000 times and 12.5% nitrile bacterium azoles wetting powder, and 7 days preventive effect is respectively 85.9% and 89.6% behind the medicine.Synergistic effect is obvious behind phonetic phenol of second and the myclobutanil compositional, and significantly better than single agent, and the consumption of active ingredient reduces to the preventive effect of powdery mildew of cucumber.
Claims (5)
1. bactericidal composition, it is characterized in that containing the phonetic phenol of second and triazole bactericidal agent Tebuconazole, Difenoconazole, own azoles alcohol or the nitrile bacterium azoles of synergy effective dose, and acceptable diluent or carrier on the agricultural chemicals, wherein the mass ratio of phonetic phenol of second and triazole bactericidal agent Tebuconazole, Difenoconazole, own azoles alcohol or nitrile bacterium azoles is 25:1 ~ 1:50.
2. according to the described bactericidal composition of claim 1, it is characterized in that: the mass ratio of phonetic phenol of second and triazole bactericidal agent Tebuconazole, Difenoconazole, own azoles alcohol or nitrile bacterium azoles is 25:1 ~ 1:25.
3. according to the described bactericidal composition of claim 1, it is characterized in that: bactericidal composition is wetting powder, suspending agent, aqueous emulsion or water dispersible granules.
4. according to the described bactericidal composition of claim 1, it is characterized in that: phonetic phenol of second and triazole bactericidal agent Tebuconazole, Difenoconazole, own azoles alcohol or the gross mass percentage composition of nitrile bacterium azoles in bactericidal composition are 5%-80%.
5. the purposes of the described bactericidal composition of claim 1 in the crop powdery mildew disease control.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100224618A CN101548677B (en) | 2009-05-12 | 2009-05-12 | Sterilizing compound of ethirimol and triazole |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100224618A CN101548677B (en) | 2009-05-12 | 2009-05-12 | Sterilizing compound of ethirimol and triazole |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101548677A CN101548677A (en) | 2009-10-07 |
| CN101548677B true CN101548677B (en) | 2011-12-07 |
Family
ID=41153354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009100224618A Active CN101548677B (en) | 2009-05-12 | 2009-05-12 | Sterilizing compound of ethirimol and triazole |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101548677B (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101632364B (en) * | 2009-05-27 | 2012-12-12 | 深圳诺普信农化股份有限公司 | Sterilization composition |
| CN101664033B (en) * | 2009-10-14 | 2012-12-19 | 成都皇牌作物科学有限公司 | Ethirimol-contained bactericide combination |
| CN101715775B (en) * | 2009-11-30 | 2013-04-17 | 福建新农大正生物工程有限公司 | Sterilizing composition containing ethirimol |
| CN102106349B (en) * | 2009-12-23 | 2013-06-12 | 中国中化股份有限公司 | Antifungal composition containing tebuconazole and pyrimidine compound |
| CN101731226B (en) * | 2010-01-05 | 2013-01-23 | 陕西美邦农资贸易有限公司 | Bactericidal composition containing ethirimol and penconazole |
| CN101999366B (en) * | 2010-12-07 | 2013-11-06 | 陕西韦尔奇作物保护有限公司 | Bactericide composition containing ethirimol |
| CN102204540B (en) * | 2011-04-02 | 2014-03-05 | 陕西汤普森生物科技有限公司 | Sterilization composite containing ethirimol and triazole compound |
| CN102349525A (en) * | 2011-09-29 | 2012-02-15 | 云南省林业科学院 | Medicine for preventing powdery mildew of Jatropha curcas L. and prevention method |
| CN104705308A (en) * | 2013-12-12 | 2015-06-17 | 南京华洲药业有限公司 | Sterilization composition containing penconazole and ethirimol, and applications thereof |
| CN107183043A (en) * | 2017-06-08 | 2017-09-22 | 合肥龙滨化工科技有限公司 | A kind of composition pesticide containing pyrazosulfuron and Difenoconazole |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1023838A1 (en) * | 1994-05-20 | 2000-08-02 | Novartis AG | Microbicide |
| CN101307024A (en) * | 2008-07-16 | 2008-11-19 | 西安近代化学研究所 | Method for synthesizing 5-nbutyl-2-ethylamido-6-methylpyrimidine-4-dimethyl amine sulfonic acid ester |
-
2009
- 2009-05-12 CN CN2009100224618A patent/CN101548677B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1023838A1 (en) * | 1994-05-20 | 2000-08-02 | Novartis AG | Microbicide |
| CN101307024A (en) * | 2008-07-16 | 2008-11-19 | 西安近代化学研究所 | Method for synthesizing 5-nbutyl-2-ethylamido-6-methylpyrimidine-4-dimethyl amine sulfonic acid ester |
Non-Patent Citations (1)
| Title |
|---|
| 周益林 等.植物白粉病的化学防治进展.《农药学学报》.2001,第3卷(第2期),12-18. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101548677A (en) | 2009-10-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101548677B (en) | Sterilizing compound of ethirimol and triazole | |
| CN101715777B (en) | Pesticide composition containing ethirimol and thiophanate-methyl, and application thereof | |
| CN102763657A (en) | Germicide composite with synergistic effect | |
| CN101595883A (en) | A kind of composition pesticide and application thereof | |
| CN101632364A (en) | Sterilization composition | |
| CN101999356A (en) | Sterilization composition containing fluopicolide and metalaxyl and application thereof | |
| CN103766353A (en) | Sterilization composition containing fluopyram | |
| CN101653139A (en) | Compound bactericidal composition containing boscalid | |
| CN102239853A (en) | Thifluzamide-containing composite bacteriacide | |
| CN102484998A (en) | Broad-spectrum combined bactericide | |
| CN101632371A (en) | Compound sterilization composition | |
| CN103609562B (en) | Compound pesticide composition containing spiral shell mite ester and flonicamid and preparation thereof | |
| CN103053538B (en) | Fungicide composition | |
| CN105638683A (en) | Agricultural bactericidal composition with saisentong | |
| CN104351209A (en) | Sterilization composition containing benzothiostrobin and propiconazole and application of sterilization composition | |
| CN101617671B (en) | Combination sterilization composition | |
| CN106857599A (en) | A kind of bactericidal composition containing pyraclostrobin and folpet and its application | |
| CN101658173A (en) | Sterilization composition containing tetraconazole | |
| CN102640757B (en) | Compound pesticide sterilization composition containing trifloxystrobin | |
| CN102754649B (en) | Sterilizing composition containing phenylate bi (imidazole) and epoxiconazole | |
| CN103609585B (en) | Composite pesticide composition containing spirodiclofen and clothianidin and preparation thereof | |
| CN101647442B (en) | Mixed sterilization combination | |
| CN101617658B (en) | Combination sterilization composition | |
| CN101690487A (en) | Agricultural bactericidal composition | |
| CN101524069A (en) | Sterilizing composition containing Hexaconazole |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |