CN102687722A - Bactericidal composition for preventing and curing powdery mildew and preparation thereof - Google Patents
Bactericidal composition for preventing and curing powdery mildew and preparation thereof Download PDFInfo
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- CN102687722A CN102687722A CN2011100686597A CN201110068659A CN102687722A CN 102687722 A CN102687722 A CN 102687722A CN 2011100686597 A CN2011100686597 A CN 2011100686597A CN 201110068659 A CN201110068659 A CN 201110068659A CN 102687722 A CN102687722 A CN 102687722A
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- bactericidal composition
- powdery mildew
- polyoxin
- bactericide
- preventing
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- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 71
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- 239000003899 bactericide agent Substances 0.000 claims abstract description 23
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to the field of pesticide preparations and discloses a bactericidal composition for preventing and curing powdery mildew. The bactericidal composition provided by the invention is composed of ethirimol and polyoxin, wherein the weight ratio of ethirimol to polyoxin is 1-99:99-1. The invention also discloses a bactericide for preventing and curing powdery mildew. An active component of the bactericide is composed of the bactericidal composition. The bactericidal composition accounts for 1-99% of the weight of the bactericide. by the adoption of the bactericidal composition and its preparation, their effects for preventing powdery mildew are remarkably raised; they have obvious synergistic effects; the amount of effective components is minimized; powdery mildew resistance is delayed; and environmental pollution is reduced. The invention can be widely applied in the agricultural field.
Description
Technical field
The present invention relates to the pesticidal preparations field, relate to a kind of bactericidal composition and preparation thereof of preventing and treating powdery mildew specifically.
Background technology
Powdery mildew is by the fungus-caused plant disease in the Erysiphaceae (Erysiphacesae); Mostly be ectoparasitism; Whole or the big portion of mycelium is exposed to the surface of leaf, stem, the tender tip, bud, flower and the fruit of host plant; And produce the macroscopic white powder that constitutes by mycelium, conidiophore and conidium in a large number, therefore be called powdery mildew.
Powdery mildew distributes extensively in China, and is particularly general to the harm of dicotyledon.After powdery mildew took place, host's position growth of being injured was suppressed, and moves back green flavescence gradually, and it is dried-up to last full leaf withered spot to occur, if many blades are injured simultaneously, also can make plant early withered.The disease later stage in the mould layer of the white powder shape that is made up of mycelia and conidium, many scattered granular cleistotheciums of black often occur, and survives the winter with this, and the inferior spring carries out just infecting with ascospore.The conidium of white powder germ all can sprout at 10-30 ℃, and is not high to humidity requirement, and normal condition can be accomplished and once infect circulation in following 10 days, and season of growth of crops can be infected repeatedly, in case its spread in china very soon takes place.Powdery mildew makes crop products such as China's wheat, cucumber, grape be subjected to very big loss, has had a strong impact on China's Agricultural Development.Therefore, how to prevent effectively that the generation of powdery mildew and propagation from just becoming the major issue in the agriculture field.
Current, the powdery mildew medicament of preventing and treating of domestic registration has 26 kinds such as triadimefon, kresoxim-methyl, Flusilazole, Difenoconazole, nitrile bacterium azoles, and the domestic powdery mildew medicament of preventing and treating has roughly experienced three phases:
Phase I is representative with inorganic sulfurs such as sulphur, lime sulfur, thiophanate methyl, mancozeb and other wide-spectrum bactericide; Such dosing is big; Preventive effect is merely about 60%, and powdery mildew is not almost had result of treatment, is mainly used in the premorbid protection; Sulphur preparation is responsive to many vegetable melon and fruits simultaneously, and most vegetable melon and fruits can not use.
Second stage is to be the triazole germicide series of representative with triazolone (triadimefon), nitrile bacterium azoles, alkene azoles alcohol, Difenoconazole, Flusilazole etc.; Such medicament improves a lot to the specific activity first generation bactericide of powdery mildew; But it is single to the germ action site; Be prone to produce cross resistance with the white powder germ, and pharmacy control efficacy is basically at 70-80%, effect is general.Simultaneously, this compounds has excitant to plant, and consumption will suppress plant growing slightly greatly, reduces output.
Phase III is to be the noval chemical compound kind of representative with the phonetic phenol of second, kresoxim-methyl, and such medicament mechanism of action is unique, and action site is more, to powdery mildew specially higher, the effect of the property controlled can reach about 90%.But, still can not prevent the generation and the propagation of powdery mildew to greatest extent.
Chinese patent CN101755842A discloses " bactericidal composition that contains kresoxim-methyl ", has comprised phonetic phenol of second and kresoxim-methyl in the said composition of this patent, in order to prevent and treat powdery mildew.But, use continuously because kresoxim-methyl is long-term, the white powder germ is produced obvious pesticide resistance, so phonetic phenol of second and kresoxim-methyl composition mainly rely on the phonetic phenol of second to realize that effect obviously reduces to the preventive effect of powdery mildew.
Summary of the invention
In view of this, the object of the invention provides a kind of bactericidal composition and preparation thereof of preventing and treating powdery mildew, makes the present invention can improve the preventive effect to powdery mildew.
For realizing the object of the invention, the present invention adopts following technical scheme:
A kind of bactericidal composition of preventing and treating powdery mildew is made up of phonetic phenol of second and polyoxin.
The phonetic phenol of second, chemical name are 5-butyl-2-ethylamino-4-hydroxyl-6-methylpyrimidine, belong to heterocyclic nitrogen-group fungicide, are the earliest to be released by the ICI company research and development of Britain.The mechanism of action of the phonetic phenol of second is the inhibitor as adenosine deaminase, and plant is played protection and therapeutic action.The phonetic phenol of second is more to the treatment site of powdery mildew, has good interior suction conductive performance, and when doing the seed dressing processing, active ingredient can absorb through root with the conduction of plant, is diffused into each position of plant, thereby plays the purpose of the whole strain crop of protection.If the phonetic phenol of second is sprayed onto leaf portion, active ingredient can absorb through blade and be transmitted to young leaves, prevents that disease from spreading to young leaves.The phonetic phenol of second waits the homoiothermy animal toxicity low to people and animals, and safer to birds, fish, consumption is few, drug effect is high, and is particularly good to mycelium and conidial killing effect.In addition, the phonetic phenol of second is degraded easily in environment, and some promotes the effect of plant growth in addition.
Polyoxin has another name called Polyoxin, multi-effect mycin; It is the biological bactericide of producing by the research and development of Japanese RIKEN, Japanese Kaken Pharmaceufical Co., Ltd.; Inhale conduction in having; Can prevent and treat multiple fungal diseases such as powdery mildew, gray mold, anthracnose, belong to peptide pyridimine nucleosides broad spectrum activity antibiotic pesticide.The structure of polyoxin exactly likes the substrate uridine 5'-diphosphate acetylglucosamine of chitin synthetase; Its affinity to chitin synthetase is nearly thousand times of uridine 5'-diphosphate acetylglucosamine; Therefore polyoxin can optionally suppress chitinous the synthesizing of composition of fungal cell wall; Simultaneously can make germ tube and mycelium part expand, break, cell inclusion releases, and causes death.In addition, polyoxin can also suppress the generation of spore and the expansion of scab.Polyoxin is to the animal avirulence, plant not only do not had poisoning but also the stimulating growth effect is arranged, and is high, free from environmental pollution to people, animal, crop safety.
The weight ratio of phonetic phenol of second according to the invention and polyoxin is 1-99: 99-1, is preferably 11.8-88.2: 88.2-11.8 further is preferably 16.7-83.3: 83.3-16.7, more preferably 76.9-83.3: 23.1-16.7.
Different fungicidal activity components mix each active component of back because the difference of composition, structure, physicochemical property makes that the synergy between each active component is typically expressed as synergistic effect, summation action or antagonism.So-called synergistic effect is exactly the mutual synergism between different material, and the effect of its generation is greater than the sum total of each composition effect; And being exactly the effect of its generation, summation action equals the sum total of each composition effect; Antagonism is meant that a kind of material disturbed the effect of another kind of material when two kinds of materials acted on living organism, or the effect of interfering with an opponent each other, the phenomenon that general effect is descended.
The present invention has carried out the controlling powdery mildew test to each composition list agent in bactericidal composition and the bactericidal composition respectively; The result shows; The preventive effect of bactericidal composition according to the invention is than the high 4-7% of preventive effect of each composition list agent in the composition; Show that each composition does not have cross tolerance in the bactericidal composition according to the invention, control efficiency has synergistic effect.
The present invention also provides a kind of bactericide of preventing and treating powdery mildew, and its active component is made up of bactericidal composition according to the invention, and the percentage by weight that said bactericidal composition accounts for said bactericide is 1-99%, is preferably 20-80%.
Bactericide according to the invention can be processed wetting powder, missible oil, suspending agent, aqua, microcapsule suspending agent or water dispersible granules by bactericidal composition according to the invention and conventional auxiliary material as required.Experiment shows that bactericide according to the invention can be prevented and treated powdery mildew effectively.
Can know that by above technical scheme the powdery mildew preventive effect of bactericidal composition according to the invention and preparation thereof significantly improves, and has the notable synergistic effect; Reduce the consumption of active ingredient; Delay the drug-fast generation of white powder germ, and reduce pollution, can be widely used in agriculture field environment.
Embodiment
The embodiment of the invention discloses a kind of bactericidal composition and preparation thereof of preventing and treating powdery mildew.Those skilled in the art can use for reference this paper content, suitably improve technological parameter and realize.Special needs to be pointed out is that all similarly replace and change apparent to those skilled in the art, they all are regarded as and are included in the present invention.Product of the present invention is described through preferred embodiment, and the related personnel obviously can change or suitably change and combination product as herein described in not breaking away from content of the present invention, spirit and scope, realizes and use technology of the present invention.
According to the present invention, said a kind of bactericidal composition of preventing and treating powdery mildew is made up of phonetic phenol of second and polyoxin.The weight ratio of phonetic phenol of second according to the invention and polyoxin is 1-99: 99-1, is preferably 11.8-88.2: 88.2-11.8 further is preferably 16.7-83.3: 83.3-16.7, more preferably 76.9-83.3: 23.1-16.7.
The present invention has carried out the controlling powdery mildew test to each composition list agent in bactericidal composition and the bactericidal composition respectively; And each composition consumption is less than each composition list agent consumption in the bactericidal composition; The result shows; Bactericidal composition according to the invention is about to the phonetic phenol of second and mixes use with polyoxin with certain proportion and have the notable synergistic effect.
The former medicine of agricultural chemicals is that active component generally can not directly be used, and must process and be mixed with various types of preparations, could use.Therefore, the present invention also provides a kind of bactericide of preventing and treating powdery mildew, and active component is made up of bactericidal composition according to the invention, and the percentage by weight that said bactericidal composition accounts for said bactericide is 1-99%, is preferably 20-80%.
The form of preparation is claimed formulation, and at present to use more be kind of formulation surplus pulvis, aqua, wetting powder, missible oil, suspending agent, microcapsule suspending agent, the water dispersible granules etc. ten to agricultural chemicals.Miticide according to the invention comprises wetting powder, missible oil, suspending agent, microcapsule suspending agent and water dispersible granules.
Wherein, wetting powder according to the invention comprises bactericidal composition, wetting agent, dispersant, carrier and inserts.Missible oil according to the invention comprises bactericidal composition, benzene or xylol and surfactant.Suspending agent according to the invention comprises bactericidal composition, wetting dispersing agent, viscosity modifier, antifreezing agent and antifoaming agent.Microcapsule suspending agent according to the invention comprises bactericidal composition, solvent, curing agent and viscosity modifier.Aqua according to the invention and water dispersible granules comprise bactericidal composition, wetting agent, disintegrant, dispersant, adhesive, interleaving agent and carrier.
Bactericide according to the invention can also be processed multiple formulations such as granule commonly used except that above-mentioned formulation, fumicants, aerosol, ultra low volume preparation, fumigant as required, to be applied to agricultural production.
Used auxiliary agent, surfactant, carrier and other auxiliary materials of various preparations is and well known to a person skilled in the art more than the preparation, is sulfonated oil, Nekal BX, soybean lecithin, thio-alcohol, hydrazides class, mercaptan acetals and polyethylene glycol oxide alkanisation ether etc. like wetting agent; Dispersant is sodium phosphate trimer, sodium pyrophosphate, lauryl sodium sulfate, cellulose derivatives, polyacrylamide, fatty acid polyethylene glycol ester and fatty alcohol oxirane etc.; Disintegrant is dried starch, sodium carboxymethyl starch, low substituted hydroxy-propyl methylcellulose, PVPP etc.; Adhesive is polyurethane, polystyrene, polyacrylate, vinyl acetate resin etc.; Solvent can be various aromatic hydrocarbons, aliphatic hydrocarbon, ketone etc.
Experiment shows that bactericide according to the invention can be prevented and treated powdery mildew effectively, like powdery mildew of cucumber etc.
In order further to understand the present invention, a kind of bactericidal composition and preparation thereof of preventing and treating powdery mildew provided by the invention is elaborated below in conjunction with embodiment.
Embodiment 1: bactericidal composition according to the invention is to the efficiency test of powdery mildew of cucumber
Test in one peasant household vegetable garden, Zhengzhou, Henan and carry out, bactericidal composition is mixed with phonetic phenol of second and polyoxin, and said bactericidal composition and each composition list agent are all with clear water dissolving back dispenser.Wherein, every processing repeats for 4 times, and the sub-district area is 30m
2, 675kg/hm in the medication of powdery mildew initial stage of origination, is pressed in totally 28 sub-districts
2, evenly spray, complied with identical consumption heavy dressing once in 7 days after the dispenser for the first time; Investigation state of an illness radix is executed 10 days " Invest, Then Investigate " preventive effects for the last time before the dispenser, fixing at random 4 points in every sub-district; Whole blades of every some investigation 2 strains, every leaf accounts for the percentage classification record of leaf area by scab, calculates disease index; Calculate control efficiency, table 1 is seen in state of an illness classification, and test is handled and the result sees table 2.
Preventive effect is calculated according to following formula:
Disease index=100 * ∑ (the sick numbers of sheets at different levels * typical values at different levels) ÷ (investigating total number of sheets * 9)
Control efficiency=[(check plot disease index growth rate-treatment region disease index growth rate) ÷ check plot disease index growth rate] * 100%
The classification of table 1 state of an illness
| 0 grade | No scab |
| 1 grade | Lesion area accounts for whole leaf area below 5% |
| 3 grades | Lesion area accounts for whole leaf area 6%～10% |
| 5 grades | Lesion area accounts for whole leaf area 11%～20% |
| 7 grades | Lesion area accounts for whole leaf area 21%～40% |
| 9 grades | Lesion area accounts for whole leaf area more than 40% |
Table 2 bactericidal composition according to the invention is to the preventive effect of powdery mildew of cucumber
| Each handles dispenser dosage (g/ hectare) | Disease index before the dispenser | Disease index after the dispenser | Preventive effect (%) |
| The phonetic phenol of second (300) | 6.23 | 7.45 | 92.25 |
| Polyoxin (60) | 5.37 | 6.62 | 93.13 |
| The phonetic phenol of second (200)+polyoxin (40) | 6.05 | 6.55 | 96.83 |
| The phonetic phenol of second (200)+polyoxin (60) | 4.43 | 4.55 | 99.24 |
| The phonetic phenol of second (255)+polyoxin (34) | 5.16 | 5.41 | 98.41 |
| The phonetic phenol of second (250)+polyoxin (50) | 5.71 | 5.72 | 99.94 |
| Clear water | 4.94 | 20.69 | 0 |
Can know by table 2 result; Phonetic phenol of active ingredient second and polyoxin are mixed; Each composition consumption is compared minimizing with each single agent consumption, and the total consumption of composition is smaller or equal to each single agent consumption, but the 4-7% of preventive effect when preventive effect is higher than each single agent and uses after the dispenser; The powdery mildew preventive effect that shows bactericidal composition according to the invention significantly improves, and has the notable synergistic effect.
Embodiment: the phonetic phenol polyoxin of 2:80% second wetting powder
The phonetic phenol of 66.7% second, 13.3% polyoxin, 5% APES fully mix with 7% fatty alcohol oxirane in proportion, and diatomite is mended to 100%, and ultrafine crusher makes wetting powder after pulverizing.
The phonetic phenol polyoxin of embodiment 3:65% second missible oil
The phonetic phenol of 50% second, 15% polyoxin, 10% benzene and 15% xylol and 10% dodecyl sodium sulfate fully mix in proportion, through the mix stirring and processing, obtain cream preparation successively.
The phonetic phenol polyoxin of embodiment 4:50% second suspending agent
The phonetic phenol of 41.7% second, 8.3% polyoxin, 2% xylonic acid sodium sulfonate, 3% alumina silicate, 5% ethylene glycol, 1% isopropyl alcohol, water benefit to 100% common process makes suspending agent.
The phonetic phenol polyoxin of embodiment 5:35% second microcapsule suspending agent
The phonetic phenol of 5.8% second, 29.2% polyoxin, 13% benzene, 30% curing agent directly are scattered in 11% polyvinyl alcohol after mixing by proportioning, add other solvent again and mend to 100%, process microcapsule suspending agent behind the slow reaction.
The phonetic phenol polyoxin of embodiment 6:20% second water dispersible granules
The phonetic phenol of 4.6% second, 15.4% polyoxin, 10% sulfonated oil, 19% sodium carboxymethyl starch, 26% sodium phosphate trimer and polystyrene, 16% calcium carbonate, 9% carrier mix; Process wetting powder after the pulverizing; Add the granulation of a certain amount of water extrusion afterwards, after dry screened, make water dispersible granules.
The phonetic phenol polyoxin aqueous solution of embodiment 7:90% second
The phonetic phenol of 75% second, 15% polyoxin, 2%Silwet618,2% ammonium sulfate, 3% polyvinyl alcohol and 2% antifoaming agent SAG622 fully mix, and water benefit to 100% common process makes aqua.
Embodiment 8: the field trial of bactericide according to the invention
The bactericide of embodiment 2 to 7 is carried out efficiency test according to the method for embodiment 1 to powdery mildew of cucumber, wheat powdery mildew, grape powdery mildew, and concrete preventive effect is seen table 3.
Table 3 bactericide according to the invention is to the preventive effect of powdery mildew
Can know that by table 3 bactericide according to the invention and said bactericidal composition have the control efficiency of same degree, can be applied to agricultural production.
The explanation of above embodiment just is used for helping to understand method of the present invention and core concept thereof.Should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the principle of the invention, can also carry out some improvement and modification to the present invention, these improvement and modification also fall in the protection domain of claim of the present invention.
Claims (8)
1. a bactericidal composition of preventing and treating powdery mildew is characterized in that, is made up of phonetic phenol of second and polyoxin.
2. according to the said bactericidal composition of claim 1, it is characterized in that the weight ratio of phonetic phenol of said second and polyoxin is 1-99: 99-1.
3. according to the said bactericidal composition of claim 2, it is characterized in that the weight ratio of phonetic phenol of said second and polyoxin is 11.8-88.2: 88.2-11.8.
4. according to the said bactericidal composition of claim 3, it is characterized in that the weight ratio of phonetic phenol of said second and polyoxin is 16.7-83.3: 83.3-16.7.
5. according to the said bactericidal composition of claim 4, it is characterized in that the weight ratio of phonetic phenol of said second and polyoxin is 76.9-83.3: 23.1-16.7.
6. a bactericide of preventing and treating powdery mildew is characterized in that, active component is made up of the said bactericidal composition of claim 1, and the percentage by weight that said bactericidal composition accounts for said bactericide is 1-99%.
7. according to the said bactericide of claim 6, it is characterized in that the percentage by weight that said bactericidal composition accounts for said bactericide is 20-80%.
8. according to the said bactericide of claim 6, it is characterized in that, process wetting powder, missible oil, suspending agent, aqua, microcapsule suspending agent or water dispersible granules by said bactericidal composition and conventional adjuvant.
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Citations (3)
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| EP2014167A1 (en) * | 2007-07-13 | 2009-01-14 | Bayer CropScience AG | Active compound combinations |
| CN101796955A (en) * | 2009-12-31 | 2010-08-11 | 青岛星牌作物科学有限公司 | Composite bactericidal composite and applications thereof |
| CN102067857A (en) * | 2011-02-23 | 2011-05-25 | 陕西美邦农药有限公司 | Fungicide combination containing polyoxin |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2014167A1 (en) * | 2007-07-13 | 2009-01-14 | Bayer CropScience AG | Active compound combinations |
| CN101796955A (en) * | 2009-12-31 | 2010-08-11 | 青岛星牌作物科学有限公司 | Composite bactericidal composite and applications thereof |
| CN102067857A (en) * | 2011-02-23 | 2011-05-25 | 陕西美邦农药有限公司 | Fungicide combination containing polyoxin |
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