CN102671011A - Traditional Chinese medicine compound powder for preventing and treating yellow and white scour of piglets and preparation method of traditional Chinese medicine compound powder - Google Patents

Traditional Chinese medicine compound powder for preventing and treating yellow and white scour of piglets and preparation method of traditional Chinese medicine compound powder Download PDF

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Publication number
CN102671011A
CN102671011A CN2012100010004A CN201210001000A CN102671011A CN 102671011 A CN102671011 A CN 102671011A CN 2012100010004 A CN2012100010004 A CN 2012100010004A CN 201210001000 A CN201210001000 A CN 201210001000A CN 102671011 A CN102671011 A CN 102671011A
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chinese medicine
medicine compound
compound powder
yellow
piglet
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CN102671011B (en
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邱妍
董发明
林霖
李祥
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Henan University of Science and Technology
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Henan University of Science and Technology
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Abstract

The invention relates to the technical field of veterinary drugs, and particularly discloses a traditional Chinese medicine compound powder for preventing and treating yellow and white scour of piglets and a preparation method of the traditional Chinese medicine compound powder. The traditional Chinese medicine compound powder for preventing and treating yellow and white scour of piglets is prepared from raw materials including, by weight, from 4 to 8 parts of radix scutellariae, from 3 to 6 parts of purslane, from 3 to 6 parts of flowers of poplar, from 2 to 4 parts of garlic, from 1 to 2 parts of pomegranate grinds and from 16 to 20 parts of rice. Incompatibility of various raw materials in the traditional Chinese medicine compound powder for preventing and treating yellow and white scour of piglets is avoided, and practice proves that the traditional Chinese medicine compound powder can obviously reduce occurrence rate of the yellow and white scour of the piglets, has an excellent prevention and treatment effect on the yellow and white scour of the piglets and is free of side effects and harmful drag residue and safe in use.

Description

A kind ofly be used to prevent and treat Chinese medicine compound powder of yellow and white dysentery of piglet and preparation method thereof
Technical field
The present invention relates to the veterinary drug technical field, be specifically related to a kind of Chinese medicine compound powder of yellow and white dysentery of piglet and preparation method thereof that is used to prevent and treat.
Background technology
China is the big country of raising pigs, and the live pig amount of delivering for sale, breeding stock and Carnis Sus domestica output all occupy first place in the world, and pig industry is occupied leading position in China's animal husbandry simultaneously, and Carnis Sus domestica has accounted for the overwhelming majority in the meat total output.Yet in Swine Production, diarrhoea has become and has caused the piglet growth one of the main reasons with high mortality of being obstructed, and has seriously hindered the sound development of pig industry.China's piglet diarrhea rate is up to 50-60%, and mortality rate reaches 15-20%.Suffering from diarrhoea modal is yellow scour of piglet, piglet pujos blancos.Yellow scour of piglet is claimed the early onset colibacillosis again, and piglet pujos blancos then is tardy property colibacillosis, and both usually follow generation.Yellow scour of piglet is mainly in 1-3 days the piglet in birth back, and piglet pujos blancos mainly betides 10-30 age in days piglet, do not have obviously seasonal, during morbidity with dysentery, to discharge milky or faint yellow thickness or medicated porridge appearance and have special stench flavor feces be characteristic.At present, mainly adopt vaccine immunity and antibiotic therapy etc. for the prevention and the treatment of yellow and white dysentery of piglet.But immune effect of vaccine is often uncertain, though antibiotic is rapid-action, cure rate is higher; But antibiotic can make the imbalance of intestine of young pigs normal flora, and influence is digested and assimilated nutrition, makes pathogen produce drug resistance; Curative effect uses antibiotic can aggravate disease on the contrary worse and worse sometimes.Maximum problem is to be prone to produce Resistant strain and drug residue.Along with the antibiotic prolongation of service time, the multi-drug resistant problem is more and more serious, and the appearance of Resistant strain makes human health also receive great threat.Many countries forbid increasing antibiotic through legislation; And China relies on one of the most serious country of antibiotic in aquaculture, therefore seeks safety, noresidue, green feed additive replaces antibiotic to become one of research focus in recent years efficiently.
The source natural sex of Chinese medicine and security reliability are its outstanding characteristics; Deriving from the Chinese medicine of animal, plant and mineral, itself is exactly the ingredient of the earth and living organism, has kept the native state and the biological activity of various constituent structure; For antibiotic; Be difficult for producing drug resistance, toxic and side effects is little, in livestock products, does not produce hazard residue.The composition that much has nutritive effect in the Chinese medicine in addition in diseases prevention, can also promote growth of animal, improve body resistance against diseases.Therefore, Chinese medicine can fundamentally solve the antibiotic remains problem that puzzlement animal husbandry develops in a healthy way, and development green cultivation industry reduces environmental pollution, has important social benefit.Chinese medicine is used for the existing a lot of reports of control of piglet bacillary dysentery at present, has also obtained certain clinical effectiveness.The Chinese medicine series products that uses at present is to be main with oral liquid, injection, several kinds of dosage forms of powder basically.The following problem of ubiquity in production application: though injection is easy to use, for preventing and treating intestinal tract disease, effect is unsatisfactory; Oral liquid absorbs better, but use inconvenient, also can exist certain stress, possibly increase the weight of the state of an illness; Powder is easy to use, but most at present powder only is to adopt general breaking method, and assimilation effect is relatively poor, and addition is big.In addition, be three fens poison of medicine, flavour of a drug are too many or dose is bigger than normal, and Chinese medicine causes bigger burden also can for the fragile digestive system of piglet, and increases drug cost.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine compound powder that is used to prevent and treat yellow and white dysentery of piglet.
The present invention also aims to provide a kind of method for preparing that is used to prevent and treat the Chinese medicine compound powder of yellow and white dysentery of piglet.
In order to realize above purpose; The technical scheme that the present invention adopted is: a kind of Chinese medicine compound powder that is used to prevent and treat yellow and white dysentery of piglet, process by the raw material of following parts by weight: Radix Scutellariae 4-8 part, Herba Portulacae 3-6 part, flower of poplar 3-6 part, Bulbus Allii 2-4 part, Pericarpium Granati 1-2 part, rice 16-20 part.
A kind of method for preparing that is used to prevent and treat the Chinese medicine compound powder of yellow and white dysentery of piglet may further comprise the steps:
(1) take by weighing raw material Radix Scutellariae, Herba Portulacae, flower of poplar, Bulbus Allii, Pericarpium Granati, rice, after raw material Radix Scutellariae, Herba Portulacae, flower of poplar, Bulbus Allii, Pericarpium Granati cold drying, micronizing gets ultra micro powder A together;
(2) with the rice parching to brown, be ground into floury afterwards, get powder material B;
(3) said ultra micro powder A and said powder material B are directly mixed, promptly make the Chinese medicine compound powder that is used to prevent and treat yellow and white dysentery of piglet.
Be used for preventing and to treat the effect of each raw material of Chinese medicine compound powder of yellow and white dysentery of piglet following: Radix Scutellariae provided by the invention: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, its pharmacological action mainly are the resisting pathogenic microbes effects; Herba Portulacae: heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, detumescence, antiinflammatory, modern medicine study shows that Herba Portulacae contains abundant vitamin A appearance material, vitamin A appearance material can be kept the normal function of epithelial tissue, promotes the reparation of mucosa; Pericarpium Granati: relieving diarrhea with astringents, hemostasis, anthelmintic can be used for treating bacillary dysentery, intestinal inflammation; Flower of poplar: heat-clearing and toxic substances removing, relieving diarrhea with astringents, removing dampness dysentery relieving, strengthening the spleen and nourishing the stomach can be used for bacillary dysentery, intestinal inflammation; Bulbus Allii: the stagnant gas of row, warming the spleen and stomach, eliminating mass is long-pending, and detoxifcation is used for flu, bacillary dysentery, amebic dysentery, enteritis, eating accumulation, carbuncle skin infection; Rice: behind the rice parching to brown, starch has become dextrin, and advantages of easy digesting more can warming the spleen and stomach, the protection gastrointestinal mucosa, helps to recover gastrointestinal function.
There is not incompatibility in each material combination of Chinese medicine compound powder that is used for preventing and treats yellow and white dysentery of piglet provided by the invention; Facts have proved that this Chinese medicine compound powder can obviously reduce the incidence rate of yellow and white dysentery of piglet; Yellow and white dysentery of piglet there are excellent prevention and therapeutical effect; And have no side effect, safe in utilization, there is not harmful drug residue.
The Chinese medicine compound powder that is used to prevent and treats yellow and white dysentery of piglet provided by the invention has the following advantages: one, raw material is easy to get, and is cheap, and cost is lower; Two, the medical material with integration of edible and medicinal herbs is main, safe; Three, not only can suppress pathogen, have the effect of prevention and treatment yellow and white dysentery of piglet, but also can strengthening the spleen and stomach, promote the reparation of intestinal mucosa, reach the effect of treating both the principal and secondary aspects of a disease; Four, Chinese medicine ingredients Radix Scutellariae, Herba Portulacae, flower of poplar, Bulbus Allii and the Pericarpium Granati in the Chinese medicine compound powder of the present invention processed the ultra micro powder through micronizing, the better absorption, and utilization rate is higher; Five, dosage form is powder, and is easy to use.
The Chinese medicine compound powder that is used to prevent and treats yellow and white dysentery of piglet provided by the invention also can be used for the prevention and the treatment of other bacillary dysenterys of poultry.
The method for using that is used to prevent and treat the Chinese medicine compound powder of yellow and white dysentery of piglet provided by the invention:
1, is used for the piglet of not weaning: with the Chinese medicine compound powder and an amount of milk powder and white sugar mixing that is used to prevent and treat yellow and white dysentery of piglet provided by the invention, add water and make half graininess that wet, place rustless steel tray food calling, logotype 5-10 days;
2, be used for ablactational baby pig: is that the ratio of 3-6% is added daily ration to, logotype 5-7 days with the Chinese medicine compound powder that is used to prevent and treats yellow and white dysentery of piglet provided by the invention according to percentage by weight;
3, be used for the piglet that do not eat: it is that 5% Glucose Liquid mixes scattered paste shape that the Chinese medicine compound powder that is used to prevent and treats yellow and white dysentery of piglet provided by the invention is used mass percent, irritates clothes, every day 50-150g, logotype 5-7 days.
The specific embodiment
Embodiment 1
Present embodiment is used to prevent and treat the Chinese medicine compound powder of yellow and white dysentery of piglet, is processed by the raw material of following parts by weight: 8 parts of Radix Scutellariaes, 3 parts of Herba Portulacaes, 3 parts of flower of poplar, 2 parts in Bulbus Allii, 2 parts of Pericarpium Granatis, 16 parts in rice.
Present embodiment is used to prevent and treat the method for preparing of the Chinese medicine compound powder of yellow and white dysentery of piglet, may further comprise the steps:
(1) take by weighing raw material Radix Scutellariae, Herba Portulacae, flower of poplar, Bulbus Allii, Pericarpium Granati, rice, after raw material Radix Scutellariae, Herba Portulacae, flower of poplar, Bulbus Allii, Pericarpium Granati cold drying, micronizing gets ultra micro powder A together;
(2) with the rice parching to brown, be ground into floury afterwards, get powder material B;
(3) said ultra micro powder A and said powder material B are directly mixed, promptly make the Chinese medicine compound powder that is used to prevent and treat yellow and white dysentery of piglet.
Embodiment 2
Present embodiment is used to prevent and treat the Chinese medicine compound powder of yellow and white dysentery of piglet, is processed by the raw material of following parts by weight: 4 parts of Radix Scutellariaes, 6 parts of Herba Portulacaes, 6 parts of flower of poplar, 4 parts in Bulbus Allii, 1 part of Pericarpium Granati, 20 parts in rice.
Present embodiment be used to prevent and the method for preparing of Chinese medicine compound powder of treating yellow and white dysentery of piglet with the method for preparing of embodiment 1.
The extracorporeal bacteria inhibitor test that is used to prevent and treat the Chinese medicine compound powder of yellow and white dysentery of piglet that Test Example 1 embodiment 1, embodiment 2 provide
Experimental technique adopts the drug sensitive test paper method, and concrete steps are:
(1) preparation bacterium liquid: the yellow and white dysentery of piglet feces dilution that will collect from the pig farm is applied on the ordinary culture medium 37 ℃ of constant temperature culture 18 hours; Cultivate through maconkey agar and EMB agar medium, microscopy is confirmed as escherichia coli; 1 escherichia coli bacterium colony of picking is inoculated in the 10mL broth medium and dilutes mixing; Make bacterium liquid, subsequent use;
(2) get the Chinese medicine compound powder 10g that is used to prevent and treat yellow and white dysentery of piglet that the embodiment of the invention 1, embodiment 2 provide respectively; Put into 100ml water respectively, soak after 30 minutes, add a cover decoction; Boil the back with slow fire boiling 30 minutes; Decoct altogether three times, the filtrating merging with three gained all is concentrated into 1g/mL; The Chinese medicine compound powder extracting solution of yellow and white dysentery of piglet and the Chinese medicine compound powder extracting solution that is used to prevent and treat yellow and white dysentery of piglet that embodiment 2 provides are prevented and treated to being used to of obtaining that embodiment 1 provides, subsequent use;
(3) preparation of Chinese medicine drug sensitive test paper: get qualitative filter paper; Process the circular paper of 6mm diameter with card punch,, place drying baker then scraps of paper sealing back autoclaving; Make its bone dry; With tweezers the scraps of paper are immersed being used for that embodiment 1 provides respectively afterwards and prevent and treat the Chinese medicine compound powder extracting solution of yellow and white dysentery of piglet and the Chinese medicine compound powder extracting solution that is used to prevent and treat yellow and white dysentery of piglet that embodiment 2 provides, make extracting solution soak into the scraps of paper fully, leave standstill and dry; Make the Chinese medicine drug sensitive test paper, subsequent use;
(4) the Chinese medicine fungistatic effect is observed: dip in the sterilization cotton swab and get the bacterium liquid that step (1) makes; Be coated in equably on the ready prepd nutrient agar panel; Treat that media surface is dry, get the Chinese medicine drug sensitive test paper that step (3) makes, be attached on the media surface with aseptic nipper; Every kind of Chinese medicine drug sensitive test paper is done three repetitions; Matched group is set in addition, and 37 ℃ of constant temperature culture were observed and are measured inhibition zone diameter after 18 hours; The inhibition zone diameter average out to 10.0mm that is used to prevent and treat the Chinese medicine compound powder extracting solution of yellow and white dysentery of piglet that embodiment 1 provides; The inhibition zone diameter average out to 9.0mm that is used to prevent and treat the Chinese medicine compound powder extracting solution of yellow and white dysentery of piglet that embodiment 2 provides, matched group is the compound Chinese medicinal preparation of certain commercially available treatment yellow and white dysentery of piglet, its inhibition zone diameter average out to 9.0mm; Through inhibition zone diameter relatively, being used to of explain that the embodiment of the invention 1 and embodiment 2 provide prevents and the Chinese medicine compound powder of treating yellow and white dysentery of piglet has the good in-vitro fungistatic effect to the pathogenicity escherichia coli.
The clinical treatment statistical test that is used to prevent and treat the Chinese medicine compound powder of yellow and white dysentery of piglet that Test Example 2 embodiment 1 provide
Newly be born piglet 20 nests time of certain pig farm, totally 264, at the 3rd day of birth, wherein there are 237 piglets to begin morbidity, suffer from totally 149 of yellow scours after diagnosing in the piglet, suffer from totally 88 of Hakuri.Being used to of adopting that the embodiment of the invention 1 provides prevents and the Chinese medicine compound powder of treating yellow and white dysentery of piglet is treated; For the fair piglet of appetite; The embodiment of the invention 1 being used to of providing prevented and treats the Chinese medicine compound powder and an amount of milk powder, white sugar mixing of yellow and white dysentery of piglet; Make partly wet graininess, place rustless steel tray food calling, logotype 7 days; For the piglet that does not eat, with the embodiment of the invention 1 being used to of providing prevent and the Chinese medicine compound powder of treating yellow and white dysentery of piglet to use mass percent be that 5% Glucose Liquid mixes scattered paste shape, irritate clothes, every day 100g, logotype 7 days carries out disinfection to colony house simultaneously.After 1 week of medication, most of piglet is all cured, and wherein the ill pig of yellow scours is cured 142, cure rate 95.3%, and other 7 the Chinese medicine compound powder treatments that continue to use the embodiment of the invention 1 were all cured after 3 days, did not have dead; The ill pig of Hakuri is cured 85, cure rate 96.6%, and other 3 are continued to use the Chinese medicine compound powder of the embodiment of the invention 1 to treat after 7 days 2 healings, 1 death.
The clinical prevention test that is used to prevent and treat the Chinese medicine compound powder of yellow and white dysentery of piglet that Test Example 3 embodiment 1 provide
There is newborn piglet yellow scours morbidity history on the pig farm, Yanshi, chooses the piglet of five sows of giving a birth on the same day and does experiment, and piglet is respectively 12,12,13,13,15, and having chosen wherein, two nests (12,13) prevent.Give a birth the same day, the Chinese medicine compound powder and an amount of milk powder and white sugar mixing that are used to prevent and treat yellow and white dysentery of piglet with the embodiment of the invention 1 provides add water and make partly wet graininess, place rustless steel tray food calling, logotype 7 days, observation every day.The situation that having loose bowels does not appear in the medication piglet, and other three nests all found have piglet to draw the situation of faint yellow loose stool in the 2nd day, 4 days after birth, and final dead 4.This test illustrative embodiment 1 provides is used to prevent and the Chinese medicine compound powder of treating yellow and white dysentery of piglet has preventive effect preferably to yellow scour of piglet.
The clinical treatment test that is used to prevent and treat the Chinese medicine compound powder of yellow and white dysentery of piglet that Test Example 4 embodiment 1 provide
The Luoyang raiser, totally 76 of a collection of piglets (15-20 age in days) have opened food, but not wean; Several piglet morbidities are arranged, and spirit is depressed, and inappetence, excrement are the canescence pulpous state; Abnormal smells from the patient is stench, and tail and hind leg are by fecal pollution, and other piglets also have infection in various degree, are piglet pujos blancos after diagnosing.Treatment: for the fair piglet of appetite,, make partly wet graininess, place rustless steel tray food calling, logotype 7 days with the Chinese medicine compound powder and an amount of milk powder, white sugar mixing that are used to prevent and treat yellow and white dysentery of piglet that the embodiment of the invention 1 provides; For the piglet that does not eat, with the embodiment of the invention 1 being used to of providing prevent and the Chinese medicine compound powder of treating yellow and white dysentery of piglet to use mass percent be that 5% Glucose Liquid mixes scattered paste shape, irritate clothes, every day 100g, logotype 7 days; Simultaneously colony house is carried out disinfection.Effect: after 1 week of medication, most of piglet all takes a turn for the better, and more serious several the piglets of the state of an illness have all recovered appetite except that 1 (the weak tire that BWt is lighter) death, after pay a return visit the rehabilitation gradually of disease piglet, do not have recurrence.

Claims (2)

1. a Chinese medicine compound powder that is used to prevent and treat yellow and white dysentery of piglet is characterized in that, is processed by the raw material of following parts by weight: Radix Scutellariae 4-8 part, Herba Portulacae 3-6 part, flower of poplar 3-6 part, Bulbus Allii 2-4 part, Pericarpium Granati 1-2 part, rice 16-20 part.
2. the described method for preparing that is used to prevent and treat the Chinese medicine compound powder of yellow and white dysentery of piglet of claim 1 is characterized in that, may further comprise the steps:
(1) take by weighing raw material Radix Scutellariae, Herba Portulacae, flower of poplar, Bulbus Allii, Pericarpium Granati, rice, after raw material Radix Scutellariae, Herba Portulacae, flower of poplar, Bulbus Allii, Pericarpium Granati cold drying, micronizing gets ultra micro powder A together;
(2) with the rice parching to brown, be ground into floury afterwards, get powder material B;
(3) said ultra micro powder A and said powder material B are directly mixed, promptly make the Chinese medicine compound powder that is used to prevent and treat yellow and white dysentery of piglet.
CN 201210001000 2012-01-04 2012-01-04 Traditional Chinese medicine compound powder for preventing and treating yellow and white scour of piglets and preparation method thereof Expired - Fee Related CN102671011B (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102895355A (en) * 2012-11-07 2013-01-30 大理金明动物药业有限公司 Chinese medicinal injection for treating livestock diarrhea and preparation method thereof
CN103191256A (en) * 2013-03-28 2013-07-10 重庆市畜牧科学院 Synbiotics traditional Chinese medicine composition for controlling white scour of piglets, and preparation method thereof
CN103893602A (en) * 2014-04-20 2014-07-02 张文艳 Simple and convenient mixed medicine with rapid antidiarrheal effect
CN105963688A (en) * 2016-06-23 2016-09-28 四川英格瑞生物科技有限公司 Powder for curing intestinal diseases of piglet and enhancing immunity and preparation method thereof
CN107308439A (en) * 2017-07-06 2017-11-03 山东中牧兽药有限公司 A kind of compound poplar flower oral liquid and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
姚永韶等: "仔猪腹泻的防治措施", 《福建畜牧兽医》 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102895355A (en) * 2012-11-07 2013-01-30 大理金明动物药业有限公司 Chinese medicinal injection for treating livestock diarrhea and preparation method thereof
CN102895355B (en) * 2012-11-07 2013-10-23 大理金明动物药业有限公司 Chinese medicinal injection for treating livestock diarrhea and preparation method thereof
CN103191256A (en) * 2013-03-28 2013-07-10 重庆市畜牧科学院 Synbiotics traditional Chinese medicine composition for controlling white scour of piglets, and preparation method thereof
CN103893602A (en) * 2014-04-20 2014-07-02 张文艳 Simple and convenient mixed medicine with rapid antidiarrheal effect
CN105963688A (en) * 2016-06-23 2016-09-28 四川英格瑞生物科技有限公司 Powder for curing intestinal diseases of piglet and enhancing immunity and preparation method thereof
CN107308439A (en) * 2017-07-06 2017-11-03 山东中牧兽药有限公司 A kind of compound poplar flower oral liquid and preparation method thereof

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