CN104322983A - Chinese medicinal composite piglet feed capable of enhancing immunity - Google Patents

Chinese medicinal composite piglet feed capable of enhancing immunity Download PDF

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Publication number
CN104322983A
CN104322983A CN201410574605.1A CN201410574605A CN104322983A CN 104322983 A CN104322983 A CN 104322983A CN 201410574605 A CN201410574605 A CN 201410574605A CN 104322983 A CN104322983 A CN 104322983A
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China
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parts
chinese medicine
main material
chinese medicinal
pig feed
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CN201410574605.1A
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沈帆
聂建彬
曹靖坤
毛志伟
韦海国
杨小树
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GUANGXI BOBAI YANGXIANG BAOZHONGBAO FEED Co Ltd
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GUANGXI BOBAI YANGXIANG BAOZHONGBAO FEED Co Ltd
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Priority to CN201410574605.1A priority Critical patent/CN104322983A/en
Publication of CN104322983A publication Critical patent/CN104322983A/en
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Abstract

The invention relates to a Chinese medicinal composite piglet feed, comprising main feed materials and Chinese medicinal additives, wherein the main feed materials comprise corn, dried corn, bean pulp, bran, barley, red sorghum, DDGS (distillers dried grains with soluble), honey and piglet premix; and the Chinese medicinal additives comprise sargentodoxa cuneata, perny false fairybells rhizome, solanum lyratum thunb and Japanese ardisia stem and leaf. The Chinese medicinal composite piglet feed is reasonable and innovative in formula and low in cost, and can improve the immunity of piglets, regulate the gastrointestinal functions of the piglets, reduce the consumption of antibiotics and improve the quality of pork at the same time.

Description

A kind of little pig feed of Chinese medicine compound of develop immunitypty
Technical field
The present invention relates to livestock-raising field, be specifically related to a kind of little pig feed of Chinese medicine compound of develop immunitypty.
Background technology
In the environment of swinery life, swinery is at every moment all in the invasion and attack that suffer from various pathogenic microorganism.Under normal conditions, the immunity of swinery body can resist the invasion of various pathogenic microorganism.But because various factors makes Swinery immunity power reduce, thus reduce the threshold of pathogen invasion its body, Swinery immunity system can not produce normal immune response, causes vaccine potency to decline, finally causes swinery generation disease simultaneously.
Along with China's pig industry is intensive, the improving constantly of large-scale degree; in addition a large amount of introducings of state foreign country kind; in feed, abuse of antibiotics keeps healthy; irrational vaccine inoculation; early weaning, frequently turns group, and hurdle is gregarious; violence such as to drive at the nervous and fight of swinery that control measures cause, cuts tooth, wound that docking, castration cause and psychology is frightened etc. makes swinery all suffer multiple stress all one's life.And stress under environment owing to being in for a long time, Swinery immunity power declines all to some extent, even if swinery does not fall ill often be in sub-health state yet.More and more difficulty is foster, swine disease is more and more finally to cause pig.Therefore stress become the very real and distinct issues that affects Production of Livestock and Poultry and economic benefit undoubtedly, cause the great attention of a lot of scholar.
Present piggy is mostly wean in about 25 days, and piglet is from being that master is transitioned into immediately based on feed with breast milk, and digestive system does not still possess the ability utilizing feed completely, Alimentary infringement can be caused (as intestinal villus is destructurized, fine hair shortens), nutrition supply is not enough, and resistance declines.After wean, piglet forwards nursery house to from farrowing house, and living condition there occurs great changes, as poultry raiser, temperature etc., all can produce a kind of uncomfortable sensation to piglet.When wean or vaccine injection grab pig, turn group, transport for long-distance concerning piglet be also one very large stress, easily cause the diseases such as allergy, heating, apocleisis, diarrhoea, oedema, growth retardation.
The functions of intestines and stomach of pig is the power producer ensureing each organ normal operation of pig body.Intestinal mucosal immune system is the first line of defence ensureing piglet health.If intestinal mucosal immune system damages, pig must take antibiotic throughout one's life.Excess antibiotic has preventive and therapeutic effect to diarrhoea and other diseases, but also can destroy intestinal beneficial bacterium, damage digestive tract function, is particularly very serious to piglet intestinal mucosal lesion.That is, there is inhibition to the speed of growth, easily produce Drug constipation.Therefore, antibiotic not only strengthens cost of raising pigs.Also be the important paathogenic factor of pig.So in order to make the genetic force of pig obtain maximum performance and reduce feeding cost, must ensure that pig is from birth to listing, the health of intestinal tract is complete.Pig has under the prerequisite of health, the growth potential that competence exertion is maximum.
And antibiotic that is a small amount of and excess all can produce drug resistance to pig.After drug resistance produces, can also with what antibiotic after pig, just use a large amount of antibiotic during sucking pig, epidemic disease refractory, has also just been understood that.And using in antibiotic process, animal body can be made to produce more peroxide, and as " free radical ", the infringement of aggravation animal body tissue and organ, makes animal active immune function be suppressed.And this increases the medication of pig undoubtedly, feeding cost can increase usually.
In piglet feed, add Chinese medicine, both can increase the immunity of piggy, its gastrointestinal function can be regulated again, to reduce antibiotic consumption, even can without antibiotic.
Summary of the invention
The object of this invention is to provide a kind of little pig feed of Chinese medicine compound of develop immunitypty.
The object of the invention is by following technical scheme realize:
The little pig feed of Chinese medicine compound of develop immunitypty of the present invention, comprise feedstuff main material and Chinese medicine additive, the raw material components of feedstuff main material and parts by weight are: dry corn 4000 ~ 6000 parts, dregs of beans 1000 ~ 2000 parts, 100 ~ 500 parts, wheat bran, barley 500 ~ 1000 parts, red sorghum 800 ~ 1500 parts, DDGS 500 ~ 1000 parts, 80 ~ 150 parts, molasses, little pig feed premix 100 ~ 500 parts; The raw material components of Chinese medicine additive and parts by weight are: Caulis mucunae Macrocarpae 3 ~ 6 parts, perny false fairybells rhizome 3 ~ 6 parts, bittersweet 3 ~ 6 parts, 3 ~ 6 parts, the Japanese ardisia.
Preferably the raw material components of feedstuff main material and parts by weight are: the raw material components of feedstuff main material and parts by weight are: dry corn 4500 ~ 5500 parts, dregs of beans 1200 ~ 1800 parts, 200 ~ 400 parts, wheat bran, barley 700 ~ 900 parts, red sorghum 900 ~ 1300 parts, DDGS 700 ~ 900 parts, 90 ~ 130 parts, molasses, little pig feed premix 200 ~ 400 parts; The raw material components of Chinese medicine additive and parts by weight are: Caulis mucunae Macrocarpae 4 ~ 5 parts, perny false fairybells rhizome 4 ~ 5 parts, bittersweet 4 ~ 5 parts, 4 ~ 5 parts, the Japanese ardisia.
Described little pig premix is made up of amino acid, vitamin, mineral element, trace element, salt.
By feedstuff main material and Chinese medicine additive mixing, stir evenly, daily feeding.
Below for adding the crude drug source of Chinese medicine:
Caulis mucunae Macrocarpae, pulse family Caulis mucunae Macrocarpae Mucuna castanea Merr., is used as medicine with old stem.Hardship, puckery, cool in nature.Enter liver, kidney two warp.Enrich blood and invigorate blood circulation, clearing away the lungheat and moisturizing, clearing and activating the channels and collaterals.Main anaemia, has through uncomfortable, lung-heat type cough, hemoptysis, soreness of waist and knee joint, arthralgia due to wind-dampness, numb in every limb, paralysis.
Perny false fairybells rhizome, Liliaceae false Disporum Salisb plant bamboo root false cantonese fairy bells Disporopsis perryi (Hua) Diels, is used as medicine with root-like stock.Sweet, flat.Yin nourishing and lung moistening, promotes the production of body fluid to quench thirst.
Bittersweet, for Solanaceae activity of Solanum Lyratum Thunb Solanum lyratum Thunb. [S. dulcamara L. var. lyratum (Thunb.) Sieb. et Zucc., S. Dulcamara L. var. pubescens Blume, S.Dulcamara L. var. chinense Dunal], be used as medicine with herb or root.Hardship, is slightly cold.Slightly poisonous.Enter liver, stomach warp.Clearing heat and detoxicating, inducing diuresis and reducing edema, anticancer.Herb: for cold, fever, acute mastitis, evil sore, jaundice with damp-heat pathogen, ascites, leukorrhea, nephritic dropsy; Carbuncle furuncle poison is controlled in external application.Root: arthralgia due to wind-dampness.
The Japanese ardisia, Myrsinacea Ardisa plant Japanese ardisia Ardisia japonica (Hornsted) Blume, is used as medicine with complete stool.Pungent, flat.Relieving cough and reducing sputum, removing toxic substances of dispeling the wind, promoting blood circulation and stopping pain.For bronchitis, lobar pneumonia, infantile pneumonia, pulmonary tuberculosis, hepatitis, dysentery, acute nephritis, urinary tract infections, stimulates the menstrual flow, traumatic injury, rheumatalgia; Skin itching is controlled in external application, dermatitis rhus.
The applicant is on the basis of research tradition piggy material formula, through Practical experiments for many years, multiple formulations is screened, have found the piggy material formula of applicable piggy physiology of growth and development feature, in feedstuff main material, add traditional Chinese medicine ingredients simultaneously, play the effect strengthening little pig immunity, even do not use antibiotic to reduce.Containing Caulis mucunae Macrocarpae, perny false fairybells rhizome, bittersweet, the Japanese ardisia in Chinese medicine additive: Caulis mucunae Macrocarpae clearing away the lungheat and moisturizing, cough-relieving is invigorated blood circulation; Perny false fairybells rhizome Yin nourishing and lung moistening, promotes the production of body fluid to quench thirst; Bittersweet is clearing heat and detoxicating, inducing diuresis and reducing edema, anticancer; The Japanese ardisia is relieving cough and reducing sputum, removing toxic substances of dispeling the wind.These Chinese medicines not only effect are remarkable, and are cheaply easy to get, and mostly are the local characteristic in Guangxi and strengthen precious jade medicine, can gather materials on the spot, enhance the immunity of piglet after using, decrease antibiotic consumption, improve the quality of pork.
In addition, also added molasses in formula major ingredient, molasses, as a kind of inexpensive feedstuff, have advantages such as digesting and assimilating fast, good palatability, reduction dust, raising granular mass.
The little pig feed of a kind of Chinese medicine compound provided by the invention has the following advantages:
1, little pig feed major ingredient formula is reasonable, meets the physilogical characteristics of piglet growth;
2, with the addition of traditional Chinese medicine ingredients, the immunity of piglet can be improved, decrease antibiotic consumption;
3, with the addition of molasses, feed digestion is absorbed fast, good palatability;
4, the present invention fills a prescription and rationally innovates, and cost is low.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.
Embodiment 1
The little pig feed of Chinese medicine compound of develop immunitypty, comprise feedstuff main material and Chinese medicine additive, the raw material components of feedstuff main material and parts by weight are: dry corn 40kg, dregs of beans 10kg, wheat bran 1kg, barley 5kg, red sorghum 8kg, DDGS 5kg, molasses 0.8kg, little pig feed premix 1kg;
The raw material components of Chinese medicine additive and parts by weight are: Caulis mucunae Macrocarpae 30g, perny false fairybells rhizome 30g, bittersweet 30g, Japanese ardisia 30g.
Described little pig premix is made up of amino acid, vitamin, mineral element, trace element, salt.
By above-mentioned feedstuff main material and Chinese medicine additive mixing, stir evenly, daily feeding.
Embodiment 2
The little pig feed of Chinese medicine compound of develop immunitypty, comprise feedstuff main material and Chinese medicine additive, the raw material components of feedstuff main material and parts by weight are: dry corn 60kg, dregs of beans 20kg, wheat bran 5kg, barley 10kg, red sorghum 15kg, DDGS 10kg, molasses 1.5kg, little pig feed premix 5kg;
The raw material components of Chinese medicine additive and parts by weight are: Caulis mucunae Macrocarpae 60g, perny false fairybells rhizome 60g, bittersweet 60g, Japanese ardisia 60g.
Described little pig premix is made up of amino acid, vitamin, mineral element, trace element, salt.
By above-mentioned feedstuff main material and Chinese medicine additive mixing, stir evenly, daily feeding.
Embodiment 3
The little pig feed of Chinese medicine compound of develop immunitypty, comprise feedstuff main material and Chinese medicine additive, the raw material components of feedstuff main material and parts by weight are: dry corn 55kg, dregs of beans 18kg, wheat bran 4kg, barley 9kg, red sorghum 13kg, DDGS 9kg, molasses 1.3kg, little pig feed premix 4kg;
The raw material components of Chinese medicine additive and parts by weight are: Caulis mucunae Macrocarpae 50g, perny false fairybells rhizome 50g, bittersweet 50g, Japanese ardisia 50g.
Described little pig premix is made up of amino acid, vitamin, mineral element, trace element, salt.
By above-mentioned feedstuff main material and Chinese medicine additive mixing, stir evenly, daily feeding.
Embodiment 4
The little pig feed of Chinese medicine compound of develop immunitypty, comprise feedstuff main material and Chinese medicine additive, the raw material components of feedstuff main material and parts by weight are: dry corn 45kg, dregs of beans 12kg, wheat bran 2kg, barley 7kg, red sorghum 9kg, DDGS 7kg, molasses 0.9kg, little pig feed premix 2kg;
The raw material components of Chinese medicine additive and parts by weight are: Caulis mucunae Macrocarpae 40g, perny false fairybells rhizome 40g, bittersweet 40g, Japanese ardisia 40g.
Described little pig premix is made up of amino acid, vitamin, mineral element, trace element, salt.
By above-mentioned feedstuff main material and Chinese medicine additive mixing, stir evenly, daily feeding.
the impact of weanling pig immunity is tested
L materials and methods
1.1 test material
The feedstuff main material of the major ingredient embodiment of the present invention 4 of 1.1.1 feeding
1.1.2 Chinese medicine additive gets the Chinese medicine additive of the embodiment of the present invention 4, by each pulverizing medicinal materials, and mixing.
1.1.3 instrument and reagent E DTA-2K anti-coagulants, GENMED blood leukocytes separating kit (Shanghai Jie Mei gene Pharmaceutical Technology Co., Ltd), PBS buffer solution (0.01mol/L, pH7.2 ~ 7.4); Uritest immunoglobulin (Ig) diagnostic kit (Guilin Uritest Group Co., Ltd); The monokaryon of the CD4 antibody of FITC fluorescence labeling little mouse-anti pig, the CD8 antibody of FITC fluorescence labeling little mouse-anti pig, the little mouse-anti pig of PE fluorescence labeling. macrophage antibody (Abcam company).HITACHI7600-010 automatic clinical chemistry analyzer (Hitachi, Ltd) Facs Calibur flow cytometer (U.S. company BD), GL-20B type refrigerated centrifuge (Anting Scientific Instrument Factory, Shanghai), TDL-5-A centrifuge (CENTRIFUGE company).
1.2 for examination pig and feeding and management
The Luchuan pig sodium selenite 48 of 25 age in days wean is chosen in test.Close according to body weight, that nest is not consistent principle is divided into 2 processed group, each processed group 24 pigs.The control group fed embodiment of the present invention 4 feedstuff main material, experimental group is fed the embodiment of the present invention 4 feedstuff main material and Chinese medicine additive.Raise phase 10d in advance, just raise phase 30d.Test is carried out in confined swine housing, cement flooring stable breeding, free choice feeding, provides sufficient clean drinking-water with Duckbill-type drinking trough.House temperature 22 DEG C ~ 25 DEG C, observes at any time and records the situation such as appetite, spirit, ight soil of pig.Duration of test, carries out immunity, expelling parasite by the routine immunization program of piglet, and adopts various ways to carry out disinfection.
1.3 method
1.3.1 blood specimen collection
After off-test, early morning, respectively from two groups of vena cava anterior blood samplings, often organize random 6, every pig aseptic collection 10 mL blood, was divided into two equal portions on an empty stomach.
1.3.2 the mensuration of serum immune globulin
A for measuring the level of serum immune globulin (IgG, IgM, IgA), the HITACHI7600-010 automatic clinical chemistry analyzer all using Hitachi, Ltd to produce, adopts terminal scattered light urbidmetry to measure.
1.3.3
Another part uses EDTA-2K anti-freezing, is separated and obtains leucocyte, move in people's centrifuge tube and add 2mL PBS buffer solution, the centrifugal 5min of 1500r/min by GENMED blood leukocytes separating kit.Quantity of leucocyte is adjusted to about 1 ~ 2 × 106cfu/mL, getting 100uL cell suspension is added in the Eppendorf pipe of 1.5mL, add appropriate fluorescently-labeled monoclonal antibody application liquid again, after 4 DEG C of effect 30min, with PBS buffer solution 3 times, 4 DEG C of centrifugal 5min of 1500r/min, abandon supernatant, add suitable PBS liquid again, application cells were tested by flow cytometry 10000 cell medium size lymphocyte CIM, CD8 and monokaryon. the positive cell ratio of macrophage.
2 results and analysis
2.1 Chinese medicine additives on weanling pig serum immune globulin to affect result as shown in table 1.
The little pig feed of Chinese medicine compound of table 1 embodiment of the present invention 4 is on the impact (unit: g/L) of weanling pig serum immune globulin
* represents P < 0.01.
Visible in IgM level by table 1, experimental group improves 19.22%(P < 0.01 than control group), in IgA level, experimental group improves 33.95%(P < 0.01 than control group), in IgG level, experimental group improves 17.65%(P < 0.01 than control group).Result of the test shows, significantly can improve the humoral immune function of body after the embodiment of the present invention 4 adds Chinese medicine in aniseed, strengthens immunity of organisms.
Although above with general explanation, detailed description of the invention and test, the present invention is described in detail, and on basis of the present invention, can make some modifications or improvements it, this will be apparent to those skilled in the art.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, all belong to the scope of protection of present invention.

Claims (4)

1. the little pig feed of Chinese medicine compound of a develop immunitypty, it is characterized in that comprising feedstuff main material and Chinese medicine additive, the raw material components of feedstuff main material and parts by weight are: dry corn 4000 ~ 6000 parts, dregs of beans 1000 ~ 2000 parts, 100 ~ 500 parts, wheat bran, barley 500 ~ 1000 parts, red sorghum 800 ~ 1500 parts, DDGS 500 ~ 1000 parts, 80 ~ 150 parts, molasses, little pig feed premix 100 ~ 500 parts; The raw material components of Chinese medicine additive and parts by weight are: Caulis mucunae Macrocarpae 3 ~ 6 parts, perny false fairybells rhizome 3 ~ 6 parts, bittersweet 3 ~ 6 parts, 3 ~ 6 parts, the Japanese ardisia.
2. the little pig feed of Chinese medicine compound as claimed in claim 1, it is characterized in that comprising feedstuff main material and Chinese medicine additive, the raw material components of feedstuff main material and parts by weight are: the raw material components of feedstuff main material and parts by weight are: dry corn 4500 ~ 5500 parts, dregs of beans 1200 ~ 1800 parts, 200 ~ 400 parts, wheat bran, barley 700 ~ 900 parts, red sorghum 900 ~ 1300 parts, DDGS 700 ~ 900 parts, 90 ~ 130 parts, molasses, little pig feed premix 200 ~ 400 parts; The raw material components of Chinese medicine additive and parts by weight are: Caulis mucunae Macrocarpae 4 ~ 5 parts, perny false fairybells rhizome 4 ~ 5 parts, bittersweet 4 ~ 5 parts, 4 ~ 5 parts, the Japanese ardisia.
3. the little pig feed of Chinese medicine compound as claimed in claim 1 or 2, is characterized in that described little pig premix is made up of amino acid, vitamin, mineral element, trace element, salt.
4. prepare the little pig feed of Chinese medicine compound described in claim 1 or 2, it is characterized in that: by feedstuff main material and Chinese medicine additive mixing, stir evenly, daily feeding.
CN201410574605.1A 2014-10-24 2014-10-24 Chinese medicinal composite piglet feed capable of enhancing immunity Pending CN104322983A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104664173A (en) * 2015-03-20 2015-06-03 江门海大饲料有限公司 Efficient environment-friendly antibiotic-free compound feed for piglets
CN104783003A (en) * 2015-05-12 2015-07-22 遵义师范学院 Chinese herbal medicine complete feed for piglets and preparation method of Chinese herbal medicine complete feed
CN105533208A (en) * 2015-12-31 2016-05-04 张明 Feed for preventing and treating porcine malignant edema
CN105876206A (en) * 2016-04-25 2016-08-24 安徽和盛伟业饲料有限公司 Growth-promoting and disease-preventing piglet feed

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101791046A (en) * 2010-04-06 2010-08-04 许雪姣 Compound feed for piglets
CN103598429A (en) * 2013-10-14 2014-02-26 当涂县湖阳兴旺园养猪场 Compound feed for piglets, and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101791046A (en) * 2010-04-06 2010-08-04 许雪姣 Compound feed for piglets
CN103598429A (en) * 2013-10-14 2014-02-26 当涂县湖阳兴旺园养猪场 Compound feed for piglets, and preparation method thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104664173A (en) * 2015-03-20 2015-06-03 江门海大饲料有限公司 Efficient environment-friendly antibiotic-free compound feed for piglets
CN104664173B (en) * 2015-03-20 2017-05-24 江门海大饲料有限公司 Efficient environment-friendly antibiotic-free compound feed for piglets
CN104783003A (en) * 2015-05-12 2015-07-22 遵义师范学院 Chinese herbal medicine complete feed for piglets and preparation method of Chinese herbal medicine complete feed
CN105533208A (en) * 2015-12-31 2016-05-04 张明 Feed for preventing and treating porcine malignant edema
CN105876206A (en) * 2016-04-25 2016-08-24 安徽和盛伟业饲料有限公司 Growth-promoting and disease-preventing piglet feed

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