CN105963688A - Powder for curing intestinal diseases of piglet and enhancing immunity and preparation method thereof - Google Patents
Powder for curing intestinal diseases of piglet and enhancing immunity and preparation method thereof Download PDFInfo
- Publication number
- CN105963688A CN105963688A CN201610460356.2A CN201610460356A CN105963688A CN 105963688 A CN105963688 A CN 105963688A CN 201610460356 A CN201610460356 A CN 201610460356A CN 105963688 A CN105963688 A CN 105963688A
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- powder
- piglet
- lipase
- cell wall
- immunity
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
- A61K38/443—Oxidoreductases (1) acting on CH-OH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses powder for curing intestinal diseases of a piglet and enhancing the immunity, and a preparation method of the powder. The powder comprises raw material components in mass percent as follows: 3%-8% of lipase, 2%-5% of glucose oxidase, 5%-10% of antimicrobial peptide, 45%-55% of yeast cell wall and 30%-35% of defatted rice bran. The powder cures the intestinal diseases of the piglet, the immunity of the piglet is also remarkably improved, the drug use is easy and do not cause any toxic or side effects on the piglet, and the low curing cost is easily accepted by a farmer.
Description
Technical field
The present invention relates to veterinary drug technical field, treat intestine of young pigs disease particularly to one and improve immunity
Powder and preparation method thereof.
Background technology
Piglet is owing to just birth thermoregulation function imperfection, undeveloped, the shortage immunity of digestive organs etc. are former
Cause, in the autumn and winter of temperature instability, piglet is most susceptible to suffer from red diarrhea, Hakuri, yellow scours.
The most conventional Therapeutic Method is to apply various antibiotic and antidysenteric, and antibiotic can have in pig body
Residue problem, same antibiotic and antidysenteric the most not only can suppression microbicide, also can press down and kill son
Probiotic bacteria in pig body, affects the digestive function of piglet.
Summary of the invention
The goal of the invention of the present invention is: the problem existed for prior art, it is provided that one treats piglet intestinal
Tract disease and powder improving immunity and preparation method thereof, solution pigling immunity is low and intestinal is sensitive is easy to get
The problem of disease, can treat intestine of young pigs disease and can improve again pigling immunity.
To achieve these goals, the technical solution used in the present invention is:
A kind of powder treating intestine of young pigs disease and improve immunity, the raw material components of described powder and matter thereof
Amount percentage ratio is: lipase 3%-8%, glucoseoxidase 2%-5%, antibacterial peptide 5%-10%, yeast is thin
Cell wall 45%-55%, defatted rice bran 30%-35%.
As the preferred version of the present invention, the raw material components of described powder and mass percent thereof it is: lipase
4%, glucoseoxidase 3%, antibacterial peptide 9%, yeast cell wall 50%, defatted rice bran 34%.
Above-mentioned treatment intestine of young pigs disease and the preparation method of the powder improving immunity, comprise the following steps:
(1) 60 mesh sieves are crossed after being pulverized respectively by raw material；
(2) by step (1) pulverize after lipase, antibacterial peptide, yeast cell wall and defatted rice bran according to
Quality proportioning mix homogeneously；
(3) adding glucoseoxidase according to quality proportioning in the mixed material of step (2), mixing is all
Even, i.e. obtain described powder.
The beneficial effects of the present invention is:
In the powder of the present invention, the function of each raw material components and effect are as follows:
Lipase: lipase controls the processes such as digestion, absorption, fat reconstruction and lipoprotein metabolism, is used for
Supplement the pancreatic lipase deficiency to fat digestion.
Glucoseoxidase: the oxidizable composition in protection powder.
Antibacterial peptide: antibacterial peptide has broad spectrum antibiotic activity, can quick killing target, and be the most a lot
The peptide of pure natural, makes it rapidly become potential medicine；Natural antibacterial peptide has selectivity immune activation
And regulatory function.
Yeast cell wall: intensify and strengthen immune system, has radiation resistance, antitumor action, antiinflammatory to make
With, help organizational structure regeneration, regulation gastrointestinal function.
Defatted rice bran: relieving constipation, reduction cholesterol, its feeding value is equivalent to Semen Maydis.
The present invention coordination with the synthesis effect by above-mentioned raw materials component, after piglet takes, had both treated piglet
Intestinal tract disease, the immunity of piglet also significantly improves, and medication is simple, piglet does not produce any poison secondary
Effect, medical expense is low, it is easy to accepted by raiser.
Detailed description of the invention
In order to make the object, technical solutions and advantages of the present invention clearer, preferred by the present invention below
Embodiment is described in detail.
Embodiment 1
A kind of powder treating intestine of young pigs disease and improve immunity, containing lipase in every 100kg powder
3kg, glucoseoxidase 5kg, antibacterial peptide 10kg, yeast cell wall 50kg, defatted rice bran 32kg.
Above-mentioned treatment intestine of young pigs disease and the preparation method of the powder improving immunity, comprise the following steps:
(1) 60 mesh sieves are crossed after being pulverized respectively by raw material；
(2) by step (1) pulverize after lipase, antibacterial peptide, yeast cell wall and defatted rice bran according to
Quality proportioning mix homogeneously；
(3) adding glucoseoxidase according to quality proportioning in the mixed material of step (2), mixing is all
Even, i.e. obtain described powder.
Embodiment 2
A kind of powder treating intestine of young pigs disease and improve immunity, containing lipase in every 100kg powder
4kg, glucoseoxidase 3kg, antibacterial peptide 9kg, yeast cell wall 50kg, defatted rice bran 34kg.
Above-mentioned treatment intestine of young pigs disease and the preparation method of the powder improving immunity, comprise the following steps:
(1) 60 mesh sieves are crossed after being pulverized respectively by raw material；
(2) by step (1) pulverize after lipase, antibacterial peptide, yeast cell wall and defatted rice bran according to
Quality proportioning mix homogeneously；
(3) adding glucoseoxidase according to quality proportioning in the mixed material of step (2), mixing is all
Even, i.e. obtain described powder.
Embodiment 3
A kind of powder treating intestine of young pigs disease and improve immunity, containing lipase in every 100kg powder
8kg, glucoseoxidase 3kg, antibacterial peptide 9kg, yeast cell wall 50kg, defatted rice bran 30kg.
Above-mentioned treatment intestine of young pigs disease and the preparation method of the powder improving immunity, comprise the following steps:
(1) 60 mesh sieves are crossed after being pulverized respectively by raw material；
(2) by step (1) pulverize after lipase, antibacterial peptide, yeast cell wall and defatted rice bran according to
Quality proportioning mix homogeneously；
(3) adding glucoseoxidase according to quality proportioning in the mixed material of step (2), mixing is all
Even, i.e. obtain described powder.
Embodiment 4
A kind of powder treating intestine of young pigs disease and improve immunity, containing lipase in every 100kg powder
5kg, glucoseoxidase 5kg, antibacterial peptide 10kg, yeast cell wall 45kg, defatted rice bran 35kg.
Above-mentioned treatment intestine of young pigs disease and the preparation method of the powder improving immunity, comprise the following steps:
(1) 60 mesh sieves are crossed after being pulverized respectively by raw material；
(2) by step (1) pulverize after lipase, antibacterial peptide, yeast cell wall and defatted rice bran according to
Quality proportioning mix homogeneously；
(3) adding glucoseoxidase according to quality proportioning in the mixed material of step (2), mixing is all
Even, i.e. obtain described powder.
Intestine of young pigs disease treatment and raising immunity test
Choosing and suffer from intestinal tract disease piglet, case piglet is randomly divided into 4 groups, often organizes 40 examples, and sets up blank right
As usual.The powder of 4 groups of the most corresponding embodiments 1-4 of ill piglet, is carried out depending on body weight and gradient of infection powder
Spice is fed, and once-a-day, uses two continuously.Result of the test is as follows:
Continuous Observation records result after 3 days, cure rate is up to 98%, and other are suffered from poultry and significantly improve, blank right
The most substantially deteriorate, it is indicated above that the powder treatment intestine of young pigs disease effects of embodiment 1-4 is notable.To controlling
More follow-up continuation of piglet after is observed 30 days, and prevalence is only 2%, shows that the immunity of piglet the most substantially carries
High.
Finally illustrate, above example only in order to technical scheme to be described and unrestricted, although
By referring to the preferred embodiments of the present invention, invention has been described, but the ordinary skill of this area
Personnel should be appreciated that and in the form and details it can be made various change, without departing from institute
The spirit and scope of the present invention that attached claims are limited.
Claims (3)
1. treat intestine of young pigs disease and the powder improving immunity for one kind, it is characterised in that: described powder
Raw material components and mass percent thereof be: lipase 3%-8%, glucoseoxidase 2%-5%, antibacterial peptide
5%-10%, yeast cell wall 45%-55%, defatted rice bran 30%-35%.
Treatment intestine of young pigs disease the most according to claim 1 and the powder improving immunity, its feature
It is: the raw material components of described powder and mass percent thereof be: lipase 4%, glucoseoxidase 3%,
Antibacterial peptide 9%, yeast cell wall 50%, defatted rice bran 34%.
3. the preparation side treating intestine of young pigs disease and the powder improving immunity described in claim 1 or 2
Method, it is characterised in that: comprise the following steps:
(1) 60 mesh sieves are crossed after being pulverized respectively by raw material；
(2) by step (1) pulverize after lipase, antibacterial peptide, yeast cell wall and defatted rice bran according to
Quality proportioning mix homogeneously；
(3) adding glucoseoxidase according to quality proportioning in the mixed material of step (2), mixing is all
Even, i.e. obtain described powder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610460356.2A CN105963688A (en) | 2016-06-23 | 2016-06-23 | Powder for curing intestinal diseases of piglet and enhancing immunity and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610460356.2A CN105963688A (en) | 2016-06-23 | 2016-06-23 | Powder for curing intestinal diseases of piglet and enhancing immunity and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105963688A true CN105963688A (en) | 2016-09-28 |
Family
ID=57022571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610460356.2A Pending CN105963688A (en) | 2016-06-23 | 2016-06-23 | Powder for curing intestinal diseases of piglet and enhancing immunity and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105963688A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106615850A (en) * | 2017-01-13 | 2017-05-10 | 山东贝瑞康生物科技有限公司 | Piglet feed additive |
| CN111567678A (en) * | 2020-05-11 | 2020-08-25 | 四川英格瑞生物科技有限公司 | Antibiotic-free livestock intestinal health-care agent and preparation method thereof |
| CN116850267A (en) * | 2023-07-13 | 2023-10-10 | 山东宝来利来生物工程股份有限公司 | Yeast cell wall-antibacterial peptide A3 composite preparation and preparation method and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102671011A (en) * | 2012-01-04 | 2012-09-19 | 河南科技大学 | Traditional Chinese medicine compound powder for preventing and treating yellow and white scour of piglets and preparation method of traditional Chinese medicine compound powder |
| CN105519798A (en) * | 2015-03-04 | 2016-04-27 | 深圳市圣西马生物技术有限公司 | Animal feed additive |
-
2016
- 2016-06-23 CN CN201610460356.2A patent/CN105963688A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102671011A (en) * | 2012-01-04 | 2012-09-19 | 河南科技大学 | Traditional Chinese medicine compound powder for preventing and treating yellow and white scour of piglets and preparation method of traditional Chinese medicine compound powder |
| CN105519798A (en) * | 2015-03-04 | 2016-04-27 | 深圳市圣西马生物技术有限公司 | Animal feed additive |
Non-Patent Citations (1)
| Title |
|---|
| 卢俊鑫等: "猪源性PR39抗菌肽对断奶仔猪生产性能、血清免疫指标和肠道菌群的影响", 《动物营养学报》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106615850A (en) * | 2017-01-13 | 2017-05-10 | 山东贝瑞康生物科技有限公司 | Piglet feed additive |
| CN111567678A (en) * | 2020-05-11 | 2020-08-25 | 四川英格瑞生物科技有限公司 | Antibiotic-free livestock intestinal health-care agent and preparation method thereof |
| CN116850267A (en) * | 2023-07-13 | 2023-10-10 | 山东宝来利来生物工程股份有限公司 | Yeast cell wall-antibacterial peptide A3 composite preparation and preparation method and application thereof |
| CN116850267B (en) * | 2023-07-13 | 2024-03-15 | 山东宝来利来生物工程股份有限公司 | Yeast cell wall-antibacterial peptide A3 composite preparation and preparation method and application thereof |
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Application publication date: 20160928 |
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