CN102657746A - Medicament for inhibiting skin decubitus and preparation method thereof - Google Patents

Medicament for inhibiting skin decubitus and preparation method thereof Download PDF

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Publication number
CN102657746A
CN102657746A CN2012101794678A CN201210179467A CN102657746A CN 102657746 A CN102657746 A CN 102657746A CN 2012101794678 A CN2012101794678 A CN 2012101794678A CN 201210179467 A CN201210179467 A CN 201210179467A CN 102657746 A CN102657746 A CN 102657746A
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parts
radix
medicine
powder
root
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CN102657746B (en
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张步天
冯枝
沈延歌
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LUOYANG WANGCAO BIOTECHNOLOGY DEVELOPMENT CO LTD
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LUOYANG WANGCAO BIOTECHNOLOGY DEVELOPMENT CO LTD
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Abstract

The invention discloses a medicament for inhibiting skin decubitus and a preparation method thereof. The medicament is prepared from the following raw medicinal materials in parts by weight: 24.5-26 parts of pseudo-ginseng, 7-7.5 parts of myrrh, 5.5-6 parts of Japanese ampelopsis root, 18-21 parts of hiraute shiny bugleweed herb, 0.7-0.9 parts of astragalus root, 0.7-0.9 parts of camphor, 8-8.5 parts of dandelion, 4.5-5 parts of seabuckthorn fruit, 25-27 parts of lightyellow sophora root and 4-6 parts of Chinese honey locust spine. The preparation method comprises the steps: preparing myrrh, Japanese ampelopsis root, hiraute shiny bugleweed herb, astragalus root, dandelion, seabuckthorn fruit, lightyellow sophora root and Chinese honey locust spine in parts by weight, chopping the raw medicinal materials so that the chopped raw medicinal materials can be placed into a cooker, placing all the chopped raw materials into the cooker, adding pure water to immerse the medicinal materials, soaking for 40-60 minutes, heating the cooker and boiling for 20-30 minutes to decoct the medicinal materials, cooling, placing medicinal liquid into a storage tank, and adding the medicinal liquid into a dosing tank by a filter; and mashing camphor, grinding the mashed camphor into 80-100 meshes powder for later use, cleaning and drying pseudo-ginseng, grinding into 80-100 meshes fine powder for later use, then adding the camphor powder and the pseudo-ginseng powder into the dosing tank, and adding the obtained mixture into a temporary storage tank through a feeding pump and the filter.

Description

A kind of medicine that suppresses the skin decubital ulcer and preparation method thereof
Technical field
The invention belongs to the Chinese medicine preparation technical field, what relate generally to is a kind of medicine that suppresses the skin decubital ulcer and preparation method thereof.
Technical background
Decubital ulcer is claimed pressure ulcer again, is because continuous ischemia takes place the long-term pressurized of local organization; Anoxia, malnutrition and cause tissue fester's necrosis is mainly in the patient of paralysis, hemiplegia, paraplegia, cerebral palsy; With the patient of stupor, the patient of gatism, old people and malnutrition, health are languisher.Clinical treatment causes that with nursing as meeting not in place the decubital ulcer complication causes death.
At present, clinically mainly contain aspect two: A, Drug therapy: adopt external iodine tincture and the effective antibiotic of intravenous drip etc. in treatment to decubital ulcer more.B, physiotherapy: adopt air fluidized bed therapy, artificial nursing, ultraviolet light therapy more.Therapeutic Method clinical drug therapy to present is unsatisfactory, utilizes Drug therapy, and the slow and state of an illness of wound healing needs keep by medicine for a long time repeatedly.The clinical care relative complex.Add patient's long-term bed and hypotrophy face, reduce patient self rehabilitation probability greatly.
Summary of the invention
The object of the present invention is to provide a kind of medicine that suppresses the skin decubital ulcer.This medicine is used for the skin decubital ulcer and has stronger inhibitory action, and is not only without any side effects, and can not cause the dependence to medicine, and more the back is difficult for recurrence.
Another object of the present invention provides the method for preparing that suppresses skin decubital ulcer medicine.This method for preparing technological process is easy, safety and sanitation.Whole flow process is accomplished in airtight equipment and pipeline fully, and middle no any exposure link can not cause any pollution to medicine.
The present invention realizes that the technical scheme that above-mentioned purpose is taked is: a kind of medicine that suppresses the skin decubital ulcer is to be that the crude drug of weight portion is processed: Radix Notoginseng 24.5-26 part, Myrrha 7-7.5 part, Radix Ampelopsis 5.5-6 part, Herba Lycopi 18-21 part, Radix Astragali 0.7-0.9 part, Camphora 0.7-0.9 part, Herba Taraxaci 8-8.5 part, Fructus Hippophae 4.5-5 part, Radix Sophorae Flavescentis 25-27 part, Spina Gleditsiae 4-6 part by following dosage.
The method for preparing of medicine of the present invention is: above-mentioned raw materials medicine Myrrha, Radix Ampelopsis, Herba Lycopi, the Radix Astragali, Herba Taraxaci, Fructus Hippophae, Radix Sophorae Flavescentis, Spina Gleditsiae are cleaned chopping to being put in the boiling pot; Mix being placed in the boiling pot, add pure water submergence medical material, soaked 40-60 minute; With decocting method boiling pot is heated to and boils; Boiling time 20-30 minute, after the cooling medicinal liquid is put into holding vessel, squeeze into material-compound tank through filter.Get Camphora and smash pulverize to pieces, it is subsequent use to reach the 80-100 order, get Radix Notoginseng clean, dry; Fine ground powdered; It is subsequent use to reach the 80-100 order, then Camphora powder and Radix Notoginseng powder is added to material-compound tank, stirs through feeding pump; Filter is squeezed into temporary jar, once is filled in the bottle that disinfects through automatic filling machine again.
The present invention can be made into unguentum, liquor, spray etc., carries, easy to use.
During the present invention formed: Radix Notoginseng contained a large amount of Saponins, has subduing swelling and relieving pain, and antiinflammatory promotes the effect of growth; Myrrha is resinous, gummy, the volatilization wet goods, has antibiotic, antiinflammatory, promoting blood circulation and stopping pain, detumescence and promoting granulation function, and multiple pathomycetes such as trichophyton, Trichophyton concentricunm, oidium schoenleinii are had inhibitory action in various degree; Radix Ampelopsis is starch-containing, and that tartaric acid etc. have is antibiotic, heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation function, and homocentricity trichophyton, microsporon audouini, epidermophyton inguinale etc. are had inhibitory action; The Herba Lycopi contains glucose, Herba Lycopi's sugar etc., has blood circulation promoting and blood stasis dispelling, line water detumescence function; Camphora contains the camphane compounds, has the dehumidifying parasite killing, and the warming and odynolysis function has the strong inhibition effect to Pilus Caprae seu Ovis appearance utricle daughter bacteria, trichophyton; The Radix Astragali contains betanin, aminoacid, choline etc., has the effect such as do not hold back for a long time of not bursting or burst of evacuation of pus, expelling pus and promoting granulation, carbuncle; Herba Taraxaci contains taraxasterol, choline, taraxacin and vitamin A, B, C etc., has heat-clearing and toxic substances removing, and the dispersing swelling and dissipating binds function has inhibitory action to the various skin fungus.Fructus Hippophae contains free fatty, Hydrocarbon, phospholipid, VE, VA etc., has the adjusting immunologically competent cell, improves the effect of immunity.Radix Sophorae Flavescentis contains alkaloid, matrine, oxymatrine, the other matrine of dextrorotation, sophoridine etc.The effect of have heat clearing and damp drying, parasite killing, Bergamot Mint Extract, mediation and convergence pore, removing skin endotoxin impurity, the growth that promotes the damaged blood vessels neurocyte and reparation, the subcutaneous blood capillary cell viability of recovery.Spina Gleditsiae contains phenols, aminoacid etc., has and invigorates blood circulation, the function of dispeling the wind.Dermatophytosis there is inhibitory action.
 
Microbial contamination testing result of the present invention:
Detect index standard value measured value
Total number of bacterial colonies≤200cfu/g<10cfu/g
The coliform bacterium must not detect
Staphylococcus aureus must not detect
Bacillus pyocyaneus must not detect
Hemolytic streptococcus must not detect
Fungus colony sum≤100cfu/g<10cfu/g
The antibacterial testing result of the present invention:
Detect index and detect number of times inhibition zone diameter meansigma methods bacteriostasis
Three 17.88mm are better for staphylococcus aureus
Three 16.12mm are better for the coliform bacterium
Three 10.72mm are better for Candida albicans
The present invention reacts Japan large rabbit one whole skin irritation:
Figure 2012101794678100002DEST_PATH_IMAGE001
The present invention is applicable to skin bacterium, fungal infection through detection.Be used for the skin decubital ulcer, wound more with.
The present invention also combines modern technology through scientific research, through for many years repeatedly research practice finally confirm.Research shows that preparation of the present invention has stronger inhibitory action to trichophyton, Trichophyton concentricunm, oidium schoenleinii, trichophyton, trichophyton, homocentricity trichophyton, microsporon audouini, epidermophyton inguinale, Staphylococcus albus, bacillus pyocyaneus etc.Rehabilitation has comparatively ideal effect to decubital ulcer, and more the back is difficult for recurrence, the present invention through clinical, feedback, follow up a case by regular visits to, add up to efficient and reach more than 90%.
The case case
Cattle, man, 68 years old now suffered from decubital ulcer in 2011, used preparation of the present invention, and the patient began external iodine tincture and injection of antibiotics class medicine two months because of ulcer appears in lie in bed all the year round buttocks and thigh of paralysis, and state of an illness effect repeatedly is undesirable.Cause the household to nurse inconvenience and self rehabilitation is slow.There was positive effect the back with the present invention in one week, the back recovery from illness of two weeks.
Liu so-and-so, the woman, suffered from decubital ulcer in 69 years old now, to each big or small hospital therapy, fail to respond to any medical treatment, 2001 use one weeks of medicinal liquid of the present invention, the affected part is good entirely, it is normal that skin recovers.
The specific embodiment
Below come further to set forth medicine of the present invention and preparation method thereof through embodiment.
Embodiment 1
The component and the weight portion of the described a kind of medicine that suppresses the skin decubital ulcer of present embodiment are following:
25.6 parts in Radix Notoginseng, 7.1 parts of Myrrhas, 5.6 parts of Radix Ampelopsis, 20.6 parts of Herba Lycopi, 0.9 part of the Radix Astragali, 0.9 part of Camphora, 8.1 parts of Herba Taraxacis, 4.6 parts of Fructus Hippophae, 26.6 parts of Radix Sophorae Flavescentiss, 5.6 parts of Spina Gleditsiaes.
Embodiment 2
The component and the weight portion of the described a kind of medicine that suppresses the skin decubital ulcer of present embodiment are following:
25 parts in Radix Notoginseng, 7.2 parts of Myrrhas, 5.8 parts of Radix Ampelopsis, 19.5 parts of Herba Lycopi, 0.8 part of the Radix Astragali, 0.8 part of Camphora, 8.2 parts of Herba Taraxacis, 4.8 parts of Fructus Hippophae, 26 parts of Radix Sophorae Flavescentiss, 5 parts of Spina Gleditsiaes.
Embodiment 3
The component and the weight portion of the described a kind of medicine that suppresses the skin decubital ulcer of present embodiment are following:
24.9 parts in Radix Notoginseng, 7.4 parts of Myrrhas, 5.9 parts of Radix Ampelopsis, 18.4 parts of Herba Lycopi, 0.7 part of the Radix Astragali, 0.7 part of Camphora, 8.4 parts of Herba Taraxacis, 4.9 parts of Fructus Hippophae, 25.4 parts of Radix Sophorae Flavescentiss, 4.4 parts of Spina Gleditsiaes.
The method for preparing of the medicine of the said inhibition skin of the foregoing description 1-3 decubital ulcer is: above-mentioned raw materials medicine Myrrha, Radix Ampelopsis, Herba Lycopi, the Radix Astragali, Herba Taraxaci, Fructus Hippophae, Radix Sophorae Flavescentis, Spina Gleditsiae are cleaned chopping by weight to being put in the boiling pot; Mix being placed in the boiling pot, add pure water submergence medical material, soaked 40-60 minute; With decocting method boiling pot is heated to and boils; Boiling time 20-30 minute, after the cooling medicinal liquid is put into holding vessel, squeeze into material-compound tank through filter.Get Camphora and smash pulverize to pieces, it is subsequent use to reach the 80-100 order, get Radix Notoginseng clean, dry; Fine ground powdered; It is subsequent use to reach the 80-100 order, then Camphora powder and Radix Notoginseng powder is added to material-compound tank, stirs through feeding pump; Filter is squeezed into temporary jar, once is filled in the bottle that disinfects through automatic filling machine again.

Claims (3)

1. medicine that suppresses the skin decubital ulcer is characterized in that: it is to be that the crude drug of weight portion is processed: Radix Notoginseng 24.5-26 part, Myrrha 7-7.5 part, Radix Ampelopsis 5.5-6 part, Herba Lycopi 18-21 part, Radix Astragali 0.7-0.9 part, Camphora 0.7-0.9 part, Herba Taraxaci 8-8.5 part, Fructus Hippophae 4.5-5 part, Radix Sophorae Flavescentis 25-27 part, Spina Gleditsiae 4-6 part by following dosage.
2. method that is used to prepare the described inhibition skin of claim 1 decubital ulcer medicine; It is characterized in that: above-mentioned raw materials medicine Myrrha, Radix Ampelopsis, Herba Lycopi, the Radix Astragali, Herba Taraxaci, Fructus Hippophae, Radix Sophorae Flavescentis, Spina Gleditsiae are cleaned chopping by weight to being put in the boiling pot; Mix being placed in the boiling pot, add pure water submergence medical material, soaked 40-60 minute; With decocting method boiling pot is heated to and boils; Boiling time 20-30 minute, after the cooling medicinal liquid is put into holding vessel, squeeze into material-compound tank through filter; Get Camphora and smash pulverize to pieces, it is subsequent use to reach the 80-100 order, get Radix Notoginseng clean, dry; Fine ground powdered; It is subsequent use to reach the 80-100 order, then Camphora powder and Radix Notoginseng powder is added to material-compound tank, stirs through feeding pump; Filter is squeezed into temporary jar, once is filled in the bottle that disinfects through automatic filling machine again.
3. method according to claim 2 is characterized in that: the medicine that said preparation suppresses the skin decubital ulcer is unguentum, liquor or spray.
CN201210179467.8A 2012-06-04 2012-06-04 Medicament for inhibiting skin decubitus and preparation method thereof Active CN102657746B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103860978A (en) * 2014-03-31 2014-06-18 张淑玲 Traditional Chinese medicine preparation for treating bedsore and preparation method thereof
CN105250711A (en) * 2015-11-16 2016-01-20 青岛麦瑞特医药技术有限公司 Traditional Chinese medicine composition for treating abdominal incision induration after cesarean delivery operation
CN107213272A (en) * 2017-06-15 2017-09-29 洛阳旺草生物技术开发有限公司 It is a kind of to treat external application Chinese medicine spray of pharyngitis and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101007066A (en) * 2006-01-25 2007-08-01 胡迪菁 Ointment for treating pressure ulcers
CN101024030A (en) * 2006-02-19 2007-08-29 巩翠贤 Medicine for preventing bedsore
CN101095841A (en) * 2007-07-16 2008-01-02 陆利群 External application medical ointment for treating decubitus and method for preparing the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101007066A (en) * 2006-01-25 2007-08-01 胡迪菁 Ointment for treating pressure ulcers
CN101024030A (en) * 2006-02-19 2007-08-29 巩翠贤 Medicine for preventing bedsore
CN101095841A (en) * 2007-07-16 2008-01-02 陆利群 External application medical ointment for treating decubitus and method for preparing the same

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103860978A (en) * 2014-03-31 2014-06-18 张淑玲 Traditional Chinese medicine preparation for treating bedsore and preparation method thereof
CN103860978B (en) * 2014-03-31 2016-04-13 薛伟 A kind of Chinese medicine preparation for the treatment of decubital ulcer and preparation method thereof
CN105250711A (en) * 2015-11-16 2016-01-20 青岛麦瑞特医药技术有限公司 Traditional Chinese medicine composition for treating abdominal incision induration after cesarean delivery operation
CN107213272A (en) * 2017-06-15 2017-09-29 洛阳旺草生物技术开发有限公司 It is a kind of to treat external application Chinese medicine spray of pharyngitis and preparation method thereof

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