CN107115415A - A kind of pharmaceutical composition for anti-infective wound healing promoting of subsiding a swelling - Google Patents
A kind of pharmaceutical composition for anti-infective wound healing promoting of subsiding a swelling Download PDFInfo
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- CN107115415A CN107115415A CN201710523619.4A CN201710523619A CN107115415A CN 107115415 A CN107115415 A CN 107115415A CN 201710523619 A CN201710523619 A CN 201710523619A CN 107115415 A CN107115415 A CN 107115415A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/84—Valerianaceae (Valerian family), e.g. valerian
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The present invention relates to technical field of traditional Chinese medicines, specifically related to a kind of pharmaceutical composition for anti-infective wound healing promoting of subsiding a swelling, it is prepared from by 11 kinds of raw material such as radix scutellariae, the coptis, golden cypress, rheum officinale, giant knotweed, garden burnet, sophora flower, Asian puccoon, field pennycress, dandelion and borneol, its medicine source is extensive, with low cost, being capable of anti-inflammation detumescence, promotion wound healing, promotion diabetic wounds, hemorrhoid postoperative patient wound healing；The pharmaceutical composition of the anti-infective wound healing promoting of detumescence provided in above-mentioned technical proposal, it is safe and reliable, it can effectively reduce dressing, hospitalizations and time.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of pharmaceutical composition of the anti-infective wound healing promoting of detumescence.
Background technology
Poor wound healing, do not recover for a long time be operation and diabetic complication and postoperation it is common the problem of.
The blood sugar level of diabetic is higher, the rise of extracellular fluid osmotic pressure, causes cell water shortage, influences wound skin healing,
The main cause that wound is difficult to heal be exactly the vessel wall thickening of lower limb arteriolar, lumen of vessels it is narrow caused by ischemic,
Poor blood circulation, fresh granulation growth is slow, along with the wound of diabetic is imbued with sugar, easily causes breed bacteria
Infection.Poor wound healing adds the pain of patient so that the extension of the treatment course of disease, painful big and easily accompanying infection, instead
Multiple infection does not recover for a long time；Doctor trained in Western medicine is typically after being cleaned a wound with hydrogen peroxide, physiological saline, alcohol, merbromin, the tincture of iodine, gentian violet etc.
Covered with sterile gauze or petrolatum gauze, although bactericidal effect is good, but can not promote cell growth, effectively kills bacterium, in advance
Anti- wound infection, while adding the pain of patient, promotes the product effect of wound healing all less to use up people's will, is badly in need of one at present
It is kind convenient, practical, can voluntarily select the medicine of promotion wound healing that uses.
The content of the invention
It is an object of the invention to provide a kind of pharmaceutical composition for anti-infective wound healing promoting of subsiding a swelling, it can remove necrosis and promote granulation
Detumescence, for poor wound healing, hemorrhoid wound be postoperative, diabetic wounds do not recover for a long time, patient provides that one kind is safe and reliable, use
The good pharmaceutical composition of effect.
In order to solve the above technical problems, present invention employs following technical scheme：
A kind of pharmaceutical composition for anti-infective wound healing promoting of subsiding a swelling, is made up of the raw material of following composition by weight：Radix scutellariae 5~
20 parts, 5~20 parts of the coptis, 5~20 parts of golden cypress, 5~20 parts of rheum officinale, 5~20 parts of giant knotweed, 5~20 parts of garden burnet, 5~20 parts of sophora flower,
5~20 parts of Asian puccoon, 5~20 parts of field pennycress, 5~30 parts of dandelion, 2~6 parts of borneol.
Preferably, the present invention is made up of the raw material of following composition by weight：15 parts of radix scutellariae, 15 parts of the coptis, 15 parts of golden cypress, rheum officinale
15 parts, 15 parts of giant knotweed, 15 parts of garden burnet, 15 parts of sophora flower, 15 parts of Asian puccoon, 15 parts of field pennycress, 20 parts of dandelion, 4 parts of borneol.
The medicine effect of wherein each raw material composition is as follows：
Radix scutellariae：【Meridian distribution of property and flavor】Bitter, cold in nature, return lung, courage, spleen, large intestine, small intestinl channel.
【Effect and effect】There is heat-clearing and damp-drying drug, cool blood is antiabortive, detoxicating functions.
The coptis：【Meridian distribution of property and flavor】Bitter, trembles with fear, thoughts of returning home warp, Liver Channel, stomach, large intestine channel.
【Effect and effect】There are heat-clearing and damp-drying drug, effect of purging intense heat and detonicating.
Golden cypress：【Meridian distribution of property and flavor】Bitter, trembles with fear, returns kidney, bladder warp.
【Effect and effect】There are heat-clearing and damp-drying drug, purging intense heat, except steaming, effect of detoxification sore treatment.
Rheum officinale：【Meridian distribution of property and flavor】Bitter, trembles with fear, returns spleen, stomach, large intestine, liver, pericardium channel.
【Effect and effect】There are heat and toxic materials clearing away, clearing heat-fire, removing pattogenic heat from the blood and toxic material from the body, dispelling stasis of blood and stimulating the menstrual flow, effect of removing dampness through diuresis and removing jaundice.
Giant knotweed：【Meridian distribution of property and flavor】Mildly bitter flavor, cold nature, Return liver, courage, lung channel.
【Effect and effect】There is removing dampness through diuresis and removing jaundice, clearing heat and detoxicating, blood stasis removing analgesic, relieving cough and reducing sputum effect.
Garden burnet：【Meridian distribution of property and flavor】Cold nature, bitter, Return liver, large intestine channel.
【Effect and effect】There are blood-stanching and blood-cooling, clearing heat and detoxicating, astringing to arrest diarrhea and suppress a variety of pathogenic microorganisms and tumour
Effect.
Sophora flower：【Meridian distribution of property and flavor】Bitter, cold nature, Return liver, large intestine channel.
【Effect and effect】There are cooling blood and hemostasis, the effect of clearing liver-fire.
Asian puccoon：【Meridian distribution of property and flavor】It is sweet, salty, tremble with fear, Thoughts of returning home bag warp, Liver Channel.
【Effect and effect】There is cool blood, invigorate blood circulation, the effect for promoting eruption of detoxifying.
Field pennycress：【Meridian distribution of property and flavor】Cool in nature, pungent, hardship returns stomach, large intestine, Liver Channel.
【Effect and effect】Have clearing heat and detoxicating, effect of removing blood stasis and expelling pus.
Dandelion：【Meridian distribution of property and flavor】Bitter but sweet flavor is trembled with fear, Return liver, stomach.
【Effect and effect】Have clearing heat and detoxicating, the effect of diuresis dissipating bind.
Borneol：【Meridian distribution of property and flavor】It is pungent, bitter, be slightly cold, the thoughts of returning home, spleen, lung channel.
【Effect and effect】There are inducing resuscitation of having one's ideas straightened out, the effect of clearing away heat to and alleviating pain.
Said medicine is made into method of the invention is：
By the radix scutellariae of above-mentioned weight proportion, the coptis, golden cypress, rheum officinale, giant knotweed, garden burnet, sophora flower, Asian puccoon, field pennycress, dandelion
Mixing is soaked after 30 points with 1000mL water, is cooked by slow fire 25~35 minutes or so rear fried to medicine, filter residues, and decoction warm is put
Enter after borneol dissolving, direct cleaning and dipping wound surface 10~20 minutes.Daily 3~5 times.
The pharmaceutical composition of the anti-infective wound healing promoting of a kind of detumescence provided in above-mentioned technical proposal, using with heat-clearing
The radix scutellariae of eliminating dampness effect, the coptis, golden cypress, giant knotweed, garden burnet with effects for removing toxic heat, field pennycress, dandelion, its medicine source are wide
It is general, convenient material drawing, safe and reliable, can anti-inflammation detumescence, promote wound healing, promote that hemorrhoid are postoperative, diabetic wounds patient wound
Mouth recovery from illness, reduces dressing, hospitalizations and time.
Embodiment
In order that objects and advantages of the present invention are more clearly understood, the present invention is carried out specifically with reference to embodiments
It is bright.It should be appreciated that following word is only to describe one or more of specific embodiments of the invention, not to the present invention
The protection domain specifically asked carries out considered critical.
Embodiment 1
A kind of pharmaceutical composition for anti-infective wound healing promoting of subsiding a swelling, is made up of the raw material of following composition by weight：Radix scutellariae 15
Part, 15 parts of the coptis, 15 parts of golden cypress, 15 parts of rheum officinale, 15 parts of giant knotweed, 15 parts of garden burnet, 15 parts of sophora flower, 15 parts of Asian puccoon, 15 parts of field pennycress,
20 parts of dandelion, 4 parts of borneol.
By the radix scutellariae of above-mentioned weight proportion, the coptis, golden cypress, rheum officinale, giant knotweed, garden burnet, sophora flower, Asian puccoon, field pennycress, dandelion
Mixing is soaked after 30 points with 1000mL water, is cooked by slow fire fried to medicine after 30 minutes, filter residue, and decoction warm inserts borneol molten
Xie Hou, direct cleaning and dipping wound surface 15 minutes.4 times a day.
Clinical observation poor wound healing patient 380, wherein diabetes 120, hemorrhoid 260.
Diagnostic criteria：All cases meet the hemorrhoid patients such as diabetic and mixed hemorrhoid, external piles.
Treatment method：Decocting warms washout.
Observation of curative effect and evaluation criteria：
1. cure：Wound healing, inflammatory resolution.
2. take a turn for the better：Wound healing, inflammation disappears substantially.
3. it is not cured：Poor wound healing, inflammation fails control.
Clinical data：Chinese medicine preparation of the present invention is efficient significantly, and effect is definite during clinical observation, and patient is not found not
Situation is as follows after good reaction and toxic side effect, treatment：
Diabetes group treats 120, takes a turn for the better 120, invalid 0, efficient up to 100%；
Hemorrhoid group treats 260, takes a turn for the better 260, invalid 0, efficient up to 100%, determined curative effect.All patients are whole
Cure.
Embodiment 2
A kind of pharmaceutical composition for anti-infective wound healing promoting of subsiding a swelling, is made up of the raw material of following composition by weight：Radix scutellariae 5
Part, 5 parts of the coptis, 5 parts of golden cypress, 5 parts of rheum officinale, 5 parts of giant knotweed, 5 parts of garden burnet, 5 parts of sophora flower, 5 parts of Asian puccoon, 5 parts of field pennycress, dandelion 5
Part, 2 parts of borneol.
By the radix scutellariae of above-mentioned weight proportion, the coptis, golden cypress, rheum officinale, giant knotweed, garden burnet, sophora flower, Asian puccoon, field pennycress, dandelion
Mixing is soaked after 30 points with 1000mL water, is cooked by slow fire fried to medicine after 35 minutes, filter residue, and decoction warm inserts borneol molten
Xie Hou, direct cleaning and dipping wound surface 20 minutes.5 times a day.
Embodiment 3
A kind of pharmaceutical composition for anti-infective wound healing promoting of subsiding a swelling, is made up of the raw material of following composition by weight：Radix scutellariae 20
Part, 20 parts of the coptis, 20 parts of golden cypress, 20 parts of rheum officinale, 20 parts of giant knotweed, 20 parts of garden burnet, 20 parts of sophora flower, 20 parts of Asian puccoon, 20 parts of field pennycress,
30 parts of dandelion, 6 parts of borneol.
By the radix scutellariae of above-mentioned weight proportion, the coptis, golden cypress, rheum officinale, giant knotweed, garden burnet, sophora flower, Asian puccoon, field pennycress, dandelion
Mixing is soaked after 30 points with 1000mL water, is cooked by slow fire fried to medicine after 25 minutes, filter residue, and decoction warm inserts borneol molten
Xie Hou, direct cleaning and dipping wound surface 10 minutes.3 times a day.
Embodiments of the present invention are explained in detail above in conjunction with embodiment, but the present invention is not limited to above-mentioned reality
Mode is applied, for those skilled in the art, after content described in the present invention is known, this hair is not being departed from
On the premise of bright principle, some equal conversion and replacement can also be made to it, these, which convert and substituted on an equal basis, also should be regarded as category
In protection scope of the present invention.
Claims (2)
1. a kind of pharmaceutical composition for anti-infective wound healing promoting of subsiding a swelling, it is characterised in that by the raw material system of following composition by weight
Into：5~20 parts of radix scutellariae, 5~20 parts of the coptis, 5~20 parts of golden cypress, 5~20 parts of rheum officinale, 5~20 parts of giant knotweed, 5~20 parts of garden burnet, Chinese scholartree
Spend 5~20 parts, 5~20 parts of Asian puccoon, 5~20 parts of field pennycress, 5~30 parts of dandelion, 2~6 parts of borneol.
2. the pharmaceutical composition of the anti-infective wound healing promoting of detumescence according to claim 1, it is characterised in that：By following heavy
The raw material of amount component is made：15 parts of radix scutellariae, 15 parts of the coptis, 15 parts of golden cypress, 15 parts of rheum officinale, 15 parts of giant knotweed, 15 parts of garden burnet, sophora flower 15
Part, 15 parts of Asian puccoon, 15 parts of field pennycress, 20 parts of dandelion, 4 parts of borneol.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710523619.4A CN107115415A (en) | 2017-06-30 | 2017-06-30 | A kind of pharmaceutical composition for anti-infective wound healing promoting of subsiding a swelling |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710523619.4A CN107115415A (en) | 2017-06-30 | 2017-06-30 | A kind of pharmaceutical composition for anti-infective wound healing promoting of subsiding a swelling |
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| CN107115415A true CN107115415A (en) | 2017-09-01 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710523619.4A Pending CN107115415A (en) | 2017-06-30 | 2017-06-30 | A kind of pharmaceutical composition for anti-infective wound healing promoting of subsiding a swelling |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110693961A (en) * | 2019-10-22 | 2020-01-17 | 王春芳 | Wanying ointment and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103705613A (en) * | 2012-10-09 | 2014-04-09 | 仇美秋 | External-use drug for treating burns and scalds |
-
2017
- 2017-06-30 CN CN201710523619.4A patent/CN107115415A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103705613A (en) * | 2012-10-09 | 2014-04-09 | 仇美秋 | External-use drug for treating burns and scalds |
Non-Patent Citations (2)
| Title |
|---|
| 徐敏洁等: "复方虎杖喷剂治疗烧伤400例", 《新中医》 * |
| 郝敏等: "虎杖液治疗瓦斯烧伤395例", 《河北中医》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110693961A (en) * | 2019-10-22 | 2020-01-17 | 王春芳 | Wanying ointment and preparation method thereof |
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Application publication date: 20170901 |