CN104547634A - Application of traditional Chinese medicinal composition for preparing medicine for treating bedsore - Google Patents

Abstract

The invention discloses application of a traditional Chinese medicinal composition for preparing medicine for treating bedsore, and belongs to the field of traditional Chinese medicine. The traditional Chinese medicinal composition for treating bedsore, provided by the invention is prepared from the following traditional Chinese medicinal materials in parts by weight: 18-32 parts of coptis chinensis wine, 18-32 parts of herba houttuyniae, 8-22 parts of gastrodiae tuber, 8-22 parts of dahurian patrinia herb, 8-22 parts of fried sophora japonica, 4-16 parts of radix gentianae macrophyllae, 4-12 parts of calomel and 0.5-5 parts of borneol. The medicine provided by the invention has the advantages that the medicine takes effect quickly and is high in effective rate and short in course of treatment, the cured bedsore does not relapse, and the like.

Description

The purposes of a kind of Chinese medicine composition in preparation treatment decubital ulcer medicine

Technical field

The invention belongs to medical art, relate to the purposes of a kind of Chinese medicine composition in preparation treatment decubital ulcer medicine.

Background technology

Decubital ulcer be body of a specified duration the friction of seat cotton-padded mattress and the ecchymosis that causes or ulcer, due to patient's prolonged illness long-term bed, seriously ill body is empty, causes local QI-blood circulation not normal, so once there is ulcer, often not easily heals.The generation of decubital ulcer adds physiology, psychological considerable distress to patient, and the person of being in a bad way can secondary septicemia, hypoproteinemia and pantatrophia, even threat to life.According to generation evolution and the clinical manifestation of decubital ulcer, clinical syndrome differentiation major embodiment accumulates the aspect such as poison, pyretic toxicity contamination in stagnation of QI-blood, blood clotting.

The Chinese medicine for the treatment of decubital ulcer has a variety of, and also existing tens, Patents document, often kind of medicine has advantages different separately or inferior position.

CN201310322700.8 discloses a kind of medicine and preparation method for the treatment of decubital ulcer, this medicine by Folium toxicodendri verniciflni, Folium jujubae, Radix Rosae Laevigatae, Pericarpium Trapae, pulvis ferri (ferrosic oxide), Flos Gomphrenae, Aerugo, Rhizoma Polygoni coriacei, Pulvis Aci, Praescutata viperina (Schmidt)., Herba Orostachyos, Lacca, the Flos Sophorae Immaturus, tomb later, herb Potentillae cryptotaeniae, Folium fici lacoris totally ten Six-element medical materials form; Medicine of the present invention has effect of blood circulation promoting and blood stasis dispelling, putrefaction-removing granulation-promoting, heat-clearing and toxic substances removing, healing up sore and subduing swelling, improves the blood circulation of patient bedridden in long term pressurized tissue, promotes that epithelial cell tissues grows fast, reaches the object for the treatment of decubital ulcer.

CN201310154385.2 is bright to be disclosed a kind of external application bedsore drug and is made up of following raw material: Rhizoma Drynariae 20-35g, Radix seu Caulis Parthenocissi tricuspidatae 15-30g, Radix Sanguisorbae 100-120g, Cortex Phellodendri 50-70g, propolis 90-115g, Radix Kalopanacis 20-35g, Rhizoma Coptidis 15-25g, Radix Glycyrrhizae 15-20g, Radix Gentianae Macrophyllae 9-13g, Radix Aconiti Kusnezoffii 3-5g(big gun), Herba Sedi Linearis 15-30g, Radix Adenophorae (Radix Glehniae) 10-25g, Radix Scutellariae 30-50g, Folium et Ramulus Callicarpae nudiflorae 30-60g, Radix Syzygii Buxifolii 15-25g, Terra Flava Usta 15-20g, Herba stachydis kouyangensis 30-50g, Herba Asplenii Vaiainte Spleenwort 10-25g, Cortex Moutan 15-30g, Borneolum Syntheticum 3-6g, Hibisci Mutabilis root 25-45g, Phymatopsis griffithiana (Hook.) J. Sm. 10-20g, Fructus Ilicis Purpureae 9-15g, Eucalyptus globulus Labill 10-15g, Herba Ipomoeae Cairicae 15-30g, common mouse ear 15-25g, Colla Corii Asini 25-50g and 50%-65% ethanol 3000ml, the party's flavour of a drug have tens kinds, scarcely medicinal herbs most in use, configuration difficulty.

Summary of the invention

The object of this invention is to provide the purposes of a kind of Chinese medicine composition in preparation treatment decubital ulcer medicine, the Chinese medicine composition flavour of a drug of this treatment decubital ulcer are few, and effective percentage is high.

In order to above-mentioned purpose, the Chinese medicine composition for the treatment of decubital ulcer provided by the invention is prepared from by the Chinese crude drug of following portions by weight:

Rhizoma Coptidis (processed with wine) 18-32 Herba Houttuyniae 18-32 Rhizoma Gastrodiae 8-22 Herba Patriniae 8-22

Flos Sophorae (parched) 8-22 Radix Gentianae Macrophyllae 4-16 Calomelas 4-12 Borneolum Syntheticum 0.5-5.

Preferably, medicine of the present invention is prepared from by the Chinese crude drug of following portions by weight:

Rhizoma Coptidis (processed with wine) 25 Herba Houttuyniae 22 Rhizoma Gastrodiae 14 Herba Patriniae 14

Flos Sophorae (parched) 14 Radix Gentianae Macrophyllae 12 Calomelas 6 Borneolum Syntheticum 1.

Rhizoma Coptidis (processed with wine): heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.

Herba Houttuyniae: heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, inducing diuresis for treating stranguria syndrome.For lung abscess vomiting pus, expectorant dyspnea of heat type is coughed, hematodiarrhoea, pyretic stranguria, carbuncle sore tumefacting virus.

Rhizoma Gastrodiae: have epilepsy, resisting throbs with fear faints, rheumatism; Calmness, spasmolytic, analgesia, tonify deficiency, suppressing the hyperactive liver to relieve the wind syndrome.Dizzy for having a headache, numb limbs and tense tendons, epilepsy clonus, tetanus.Feel dizzy, neurasthenia, anemofrigid-damp arthralgia, infantile convulsion.

Herba Patriniae: heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, blood circulation promoting competent silt.For acute appendicitis, lung abscess and sore and toxic, the stagnant caused breast abdomen pain of the excess-heat stasis of blood, the diseases such as the stagnant stomachache of the stasis of blood in puerperal.

Flos Sophorae (parched): cooling blood for hemostasis, purging liver-fire.For having blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, spit blood, epistaxis, liver-heat conjunctival congestion, has a headache dizzy.Flos Sophorae (parched): get clean Flos Sophorae, fries to surperficial buff according to Chinese Pharmacopoeia method of frying.

Radix Gentianae Macrophyllae: expelling wind and removing dampness, and blood relaxing muscles and tendons, clearing away heat and promoting diuresis.Dispelling the wind and dampness pathogens arthralgia pain, muscles and bones contracture, jaundice, has blood in stool, osteopyrexia and fever, children's's infantile malnutrition with fever, dysuria.

Calomelas: parasite killing, counteracting toxic substances, diuretic, relieving constipation.Control scabies, scrofula, syphilis, primary sore, skin ulcer, edema, tympanites, defecation is closed.

Borneolum Syntheticum: refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.Faint for calentura coma, convulsion, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors is gone into a coma, and conjunctival congestion, aphtha, laryngopharynx swelling and pain, auditory meatus is suppurated.

Present invention also offers the preparation method of the Chinese medicine composition of this treatment decubital ulcer, comprise following steps

1) Rhizoma Coptidis (processed with wine), Herba Houttuyniae, Rhizoma Gastrodiae, Herba Patriniae, Flos Sophorae (parched), Radix Gentianae Macrophyllae, Calomelas, Borneolum Syntheticum is taken;

2) be ground into coarse powder, the percent by volume adding medical material total weight parts 3-6 times amount is 75% ethanol, stirs, is heated to 60-70 DEG C, is incubated 6 hours, after natural cooling, places 7 days, filters, filtrate is bottled.

The Chinese medicine composition tool that the present invention treats decubital ulcer has the following advantages:

1. instant effect, effective percentage is high, short treating period, does not recur.

2. flavour of a drug are few, and medical material used is pharmacopeia medicinal herbs most in use, are easy to buy.

clinical data

98 routine patients are the inpatient that my institute in March, 2010 ~ 2014 are accepted for medical treatment year August.Wherein male 52 example, women 46 example, 60 to 80 years old ages not etc., wherein I phase decubital ulcer 40 example, II phase decubital ulcer 54 example, III phase decubital ulcer 4 example.

therapeutic Method

2.1 Pharmaceutical formulations

Get Rhizoma Coptidis (processed with wine) 25g, Herba Houttuyniae 22 g, Rhizoma Gastrodiae 14 g, Herba Patriniae 14 g, Flos Sophorae (parched) 14 g, Radix Gentianae Macrophyllae 12 g, Calomelas 6 g, Borneolum Syntheticum 1; Be ground into coarse powder, the percent by volume adding medical material total weight parts 4 times amount is 75% ethanol, stirs, and is heated to 65 DEG C, is incubated 6 hours, after natural cooling, places 7 days, filters, by for subsequent use for the spray of filtrate dress.

2.2 Therapeutic Method:

I phase decubital ulcer, first cleans affected part with normal saline gauze, medicinal liquid is warmed to 38 ~ 42 DEG C, is soaked into by dressing (3 ~ 4 gauze), is screwed onto after not dripping, spreads on affected part, within 3 ~ 5 minutes, changes 1 time, applies 10 ~ 20 minutes, every day 2 ~ 3 times at every turn, until healing.

II phase decubital ulcer, uses 0.5% iodophor disinfection around skin ulcer face, skin ulcer face normal saline and hydrogen peroxide alternately rinse.II phase decubital ulcer generally has vesicle to be formed, and under sterile working, can pump liquid in bleb with syringe needle, and less vesicle can drawing liquid, allows its absorbed themselves.Then soak into dressing (3 ~ 4 layers of gauze) with the medicinal liquid of 38 ~ 42 DEG C, be screwed onto after not dripping, spread on affected part, within 3 ~ 5 minutes, change 1 time, apply 10 ~ 20 minutes, every day 3 ~ 5 times at every turn, until healing.

III phase decubital ulcer, thoroughly should expand wound, removes decay and necrosis tissue, to ill-defined slough, has a little oozing of blood to remove to local.If any necrotic bone, application rongeur is stung and is removed.With 3% hydrogen peroxide or 0.1% bromo geramine cleaning wound surface, then soak into dressing (3 ~ 4 layers of gauze) with the medicinal liquid of 38 ~ 42 DEG C, be screwed onto after not dripping, spread on affected part, within 3 ~ 5 minutes, change 1 time, apply 10 ~ 20 minutes, every day 4 ~ 6 times at every turn, until healing.

3 experimental results

After the traditional Chinese medicine composition for treating that the present invention treats decubital ulcer, 98 routine patients with bedsore are all cured, and cure rate is 100%, wherein 40 example I phase patients with bedsore, and the average healing days in skin ulcer face is 3 days.54 example II phase patients with bedsore, skin ulcer face the average healing is 6 days.4 example III phase patients with bedsore, area is large, and skin ulcer face is comparatively dark, and skin ulcer face the average healing is 20 days.Treatments period has no obvious adverse reaction.Tracing observation is carried out 3 months to all healing patients, has no recurrent cases.

Detailed description of the invention

Below will further illustrate the present invention by specific embodiment, but it should be appreciated by those skilled in the art that the specific embodiment of the invention and do not limit the present invention in any way.Take up an official post on basis of the present invention and how all fall within protection scope of the present invention with replacement.The technology contents of the not detailed description of the present invention is known technology.

eXAMPLE l

Get Rhizoma Coptidis (processed with wine) 25g, Herba Houttuyniae 22 g, Rhizoma Gastrodiae 14 g, Herba Patriniae 14 g, Flos Sophorae (parched) 14 g, Radix Gentianae Macrophyllae 12 g, Calomelas 6 g, Borneolum Syntheticum 1; Be ground into coarse powder, the percent by volume adding medical material total weight parts 4 times amount is 75% ethanol, stirs, and is heated to 65 DEG C, is incubated 6 hours, after natural cooling, places 7 days, filters, by for subsequent use for the spray of filtrate dress.

embodiment 2

Get Rhizoma Coptidis (processed with wine) 25g, Herba Houttuyniae 22 g, Rhizoma Gastrodiae 20 g, Herba Patriniae 20g, Flos Sophorae (parched) 12g, Radix Gentianae Macrophyllae 10 g, Calomelas 5, Borneolum Syntheticum 2; Be ground into coarse powder, the percent by volume adding medical material total weight parts 3 times amount is 75% ethanol, stirs, and is heated to 70 DEG C, is incubated 6 hours, after natural cooling, places 7 days, filters, by for subsequent use for the spray of filtrate dress.

embodiment 3

Get Rhizoma Coptidis (processed with wine) 30g, Herba Houttuyniae 228g, Rhizoma Gastrodiae 16 g, Herba Patriniae 10 g, Flos Sophorae (parched) 10 g, Radix Gentianae Macrophyllae 12g, Calomelas 10 g, Borneolum Syntheticum 1.5; Be ground into coarse powder, the percent by volume adding medical material total weight parts 4 times amount is 75% ethanol, stirs, and is heated to 65 DEG C, is incubated 6 hours, after natural cooling, places 7 days, filters, by for subsequent use for the spray of filtrate dress.

embodiment 4

Get Rhizoma Coptidis (processed with wine) 20g, Herba Houttuyniae 20 g, Rhizoma Gastrodiae 20g, Herba Patriniae 20 g, Flos Sophorae (parched) 20 g, Radix Gentianae Macrophyllae 15g, Calomelas 10g, Borneolum Syntheticum 3; Be ground into coarse powder, the percent by volume adding medical material total weight parts 4 times amount is 75% ethanol, stirs, and is heated to 65 DEG C, is incubated 6 hours, after natural cooling, places 7 days, filters, by for subsequent use for the spray of filtrate dress.

Claims (3)

1. the purposes of Chinese medicine composition in preparation treatment decubital ulcer medicine, it is characterized in that, described Chinese medicine composition is prepared from by the Chinese crude drug of following portions by weight:

Rhizoma Coptidis (processed with wine) 18-32 Herba Houttuyniae 18-32 Rhizoma Gastrodiae 8-22 Herba Patriniae 8-22

Flos Sophorae (parched) 8-22 Radix Gentianae Macrophyllae 4-16 Calomelas 4-12 Borneolum Syntheticum 0.5-5.

2. purposes according to claim 1, is characterized in that, described Chinese medicine composition is prepared from by the Chinese crude drug of following portions by weight:

Rhizoma Coptidis (processed with wine) 25 Herba Houttuyniae 22 Rhizoma Gastrodiae 14 Herba Patriniae 14

Flos Sophorae (parched) 14 Radix Gentianae Macrophyllae 12 Calomelas 6 Borneolum Syntheticum 1.

3. purposes according to claim 1 and 2, is characterized in that, the preparation method of described Chinese medicine composition, comprises following steps

1) Rhizoma Coptidis (processed with wine), Herba Houttuyniae, Rhizoma Gastrodiae, Herba Patriniae, Flos Sophorae (parched), Radix Gentianae Macrophyllae, Calomelas, Borneolum Syntheticum is taken;

2) be ground into coarse powder, the percent by volume adding medical material total weight parts 3-6 times amount is 75% ethanol, stirs, is heated to 60-70 DEG C, is incubated 6 hours, after natural cooling, places 7 days, filters, filtrate is bottled.