CN103272053A - Topical ointment for treating bedsores and preparation method thereof - Google Patents
Topical ointment for treating bedsores and preparation method thereof Download PDFInfo
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- CN103272053A CN103272053A CN2013102208404A CN201310220840A CN103272053A CN 103272053 A CN103272053 A CN 103272053A CN 2013102208404 A CN2013102208404 A CN 2013102208404A CN 201310220840 A CN201310220840 A CN 201310220840A CN 103272053 A CN103272053 A CN 103272053A
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Abstract
The invention relates to a topical ointment for treating bedsores and a preparation method thereof. The topical ointment is characterized in that the topical ointment is made from the following raw medicines, by weight, 22-28 parts of codonopsis pilosula, 22-28 parts of lumbricus, 18-22 parts of gallnut, 18-22 parts of rheum officinale, 10-14 parts of poria cocos, 10-14 parts of Chinese angelica, 10-14 parts of frankincense, 9-11 parts of angelica dahurica, 9-11 parts of myrrh, 9-11 parts of radix rehmanniae, 9-11 parts of oldenlandia diffusa, 9-11 parts of lithospermum, 6-8 parts of bighead atractylodes rhizome, 6-8 parts of white peony root, 6-8 parts of coptis, 4-6 parts of licorice, 1-3 parts of borneol, 0.8-1.2 parts of verdigris, and 0.8-1.2 parts of calomel. The topical ointment is advantaged by rapid effects and significant effects without leaving scars. Through clinical verifications, the effective rate of the topical ointment for treating bedsores is 100%. [0]
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine pharmacy, particularly relate to a kind of external-applied ointment for the treatment of decubital ulcer and preparation method thereof.
Background technology
Decubital ulcer is many, and QI-blood circulation is lost smooth because of the prolonged illness bed, failure of skin and muscle to be nourished, and every because the friction skin is broken, contamination forms.Be mainly in pressurized position easily such as tail sacrum, elbow ankle, ridge, with the skin ulceration, the open sore part is prolonged more not to be feature.
At present, the treatment decubital ulcer mainly is to take infrared ray radiation, put Gentian Violet and excision on the skin, and thick skin-grafting or flap, muscle flap, musculo cutaneous flap shift that to repair be main in the row, has treatment time length, weak effect, stays deficiency such as cicatrix easily.
Summary of the invention
The technical problem to be solved in the present invention is: for solving the deficiencies in the prior art, the invention provides a kind of external-applied ointment for the treatment of decubital ulcer and preparation method thereof, have the advantage of instant effect, evident in efficacy, preventing from scar.
A kind of external-applied ointment for the treatment of decubital ulcer is characterized in that: made by following bulk drugs: Radix Codonopsis 22-28 part, Pheretima 22-28 part, Galla Chinensis 18-22 part, Radix Et Rhizoma Rhei 18-22 part, Poria 10-14 part, Radix Angelicae Sinensis 10-14 part, Olibanum 10-14 part, Radix Angelicae Dahuricae 9-11 part, Myrrha 9-11 part, Radix Rehmanniae 9-11 part, Herba Hedyotidis Diffusae 9-11 part, Radix Arnebiae (Radix Lithospermi) 9-11 part, Rhizoma Atractylodis Macrocephalae 6-8 part, Radix Paeoniae Alba 6-8 part, Rhizoma Coptidis 6-8 part, Radix Glycyrrhizae 4-6 part, Borneolum Syntheticum 1-3 part, Aerugo 0.8-1.2 part, Calomelas 0.8-1.2 part.
The external-applied ointment of described treatment decubital ulcer is characterized in that: made by following bulk drugs: 25 parts of Radix Codonopsis, 25 parts of Pheretimas, 20 parts of Galla Chinensiss, 20 parts of Radix Et Rhizoma Rhei, 12 parts in Poria, 12 parts of Radix Angelicae Sinensis, 12 parts of Olibanums, 10 parts of the Radixs Angelicae Dahuricae, 10 parts of Myrrhas, 10 parts of Radix Rehmanniae, 10 parts of Herba Hedyotidis Diffusaes, 10 parts of Radix Arnebiae (Radix Lithospermi)s, 7 parts of the Rhizoma Atractylodis Macrocephalaes, 7 parts of the Radix Paeoniae Albas, 7 parts of Rhizoma Coptidis, 5 parts in Radix Glycyrrhizae, 2 parts of Borneolum Syntheticums, 1 part of Aerugo, 1 part of Calomelas.
The preparation method of the external-applied ointment of described treatment decubital ulcer may further comprise the steps:
(1) according to described parts by weight weighting raw materials: Radix Codonopsis, Pheretima, Galla Chinensis, Radix Et Rhizoma Rhei, Poria, Radix Angelicae Sinensis, Olibanum, the Radix Angelicae Dahuricae, Myrrha, Radix Rehmanniae, Herba Hedyotidis Diffusae, Radix Arnebiae (Radix Lithospermi), the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Rhizoma Coptidis, Radix Glycyrrhizae, Borneolum Syntheticum, Aerugo, Calomelas are standby;
(2) crude drug that will take by weighing is crushed to the 80-100 order, sterilization, mixing; Make ointment with conventional method.
Usage and consumption: conventional method carries out after the debridement treatment this ointment evenly being applied to the decubital ulcer position, and wrapping gets final product; The patient changes dressings once every day; 7 days is a course for the treatment of.
The pharmaceutical characteristic of each crude drug of the present invention is as follows:
Radix Codonopsis: meridian distribution of property and flavor: sweet, flat, return spleen, lung meridian; Effect: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.
Pheretima: meridian distribution of property and flavor: salty, cold, return liver, spleen, urinary bladder channel; Effect: the heat clearing away arresting convulsion, collateral dredging is relievingd asthma, diuresis.
Galla Chinensis: meridian distribution of property and flavor: sour, puckery, cold; Return lung, large intestine, kidney channel; Effect: the pathogenic fire reducing of astringing the lung, relieving diarrhea with astringents, the arresting sweating hemostasis, removing dampness is held back skin ulcer.
Radix Et Rhizoma Rhei: meridian distribution of property and flavor: bitter, cold, return spleen, stomach, large intestine, liver, pericardium channel; Effect: purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.
Poria: meridian distribution of property and flavor: sweet, light, flat, GUIXIN, lung, spleen, kidney channel; Effect: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.
Radix Angelicae Sinensis: meridian distribution of property and flavor: sweet, hot, warm; Return liver, the heart, spleen channel; Effect: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation.
Olibanum: meridian distribution of property and flavor: suffering, hardship, tepor; GUIXIN, liver, spleen channel; Effect: blood-activating and qi-promoting, inducing menstruation to relieve menalgia, detumescence and promoting granulation.
The Radix Angelicae Dahuricae: meridian distribution of property and flavor: suffering, temperature is returned stomach, large intestine, lung meridian; Effect: the wind dehumidifying of loosing, understand things pain-stopping, detumescence and apocenosis.
Myrrha: meridian distribution of property and flavor: hardship, flat; Return Liver Channel; Effect: the blood blood stasis removing that looses, subduing swelling and relieving pain.
Radix Rehmanniae: meridian distribution of property and flavor: sweetness and bitterness, the heart, liver, kidney channel are gone in cold; Effect:: heat clearing away, the YIN nourishing of promoting the production of body fluid nourishes blood.
Herba Hedyotidis Diffusae: meridian distribution of property and flavor: sweet, light, stomach, large intestine, small intestine meridian are returned in cold; Effect:: heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain.
Radix Arnebiae (Radix Lithospermi): meridian distribution of property and flavor: sweet, salty, cold, GUIXIN, Liver Channel; Effect: removing heat from blood, invigorate blood circulation the detoxifcation rash.
The Rhizoma Atractylodis Macrocephalae: meridian distribution of property and flavor: bitter, sweet, warm, return spleen, stomach warp; Effect: invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.
The Radix Paeoniae Alba: meridian distribution of property and flavor: be slightly cold, bitter, sour, return liver, spleen channel; Effect: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.
Rhizoma Coptidis: meridian distribution of property and flavor: hardship, cold, GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel; Effect: heat clearing and damp drying, eliminating fire and detoxication.
Radix Glycyrrhizae: meridian distribution of property and flavor: sweet, flat, GUIXIN, lung, spleen, stomach warp; Effect: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
Borneolum Syntheticum: meridian distribution of property and flavor: hot, bitter, be slightly cold; GUIXIN, spleen, lung meridian; Effect: the refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.Aerugo: meridian distribution of property and flavor: sour and astringent, flat, poisonous; Return liver, gallbladder meridian; Effect: nebula removing, removing the necrotic tissue is held back skin ulcer, and parasite killing is told wind-phlegm.
Calomelas: meridian distribution of property and flavor: suffering, cold, poisonous; Return large intestine, small intestine meridian; Effect: the external parasite killing, counteracting toxic substances is held back skin ulcer; The removing food stagnancy that eliminates the phlegm for oral administration, the relieving constipation of relieving oedema or abdominal distension through diuresis or purgation.
The present invention is under Traditional Chinese medical theory and clinical experience guidance, chooses above-mentioned each crude drug and proportioning thereof and makes ointment, has the effect of heat-clearing and toxic substances removing, antibiotic analgesia, nourishing YIN and benefiting blood, putrefaction-removing granulation-promoting, thereby reaches the purpose for the treatment of decubital ulcer.
The beneficial effect that the present invention compared with prior art has is: the present invention has the advantage of instant effect, evident in efficacy, preventing from scar; Through clinical verification, the present invention is 100% for the effective percentage for the treatment of decubital ulcer.
The specific embodiment
Embodiment 1:
A kind of external-applied ointment for the treatment of decubital ulcer is made by following bulk drugs: 25 parts of Radix Codonopsis, 25 parts of Pheretimas, 20 parts of Galla Chinensiss, 20 parts of Radix Et Rhizoma Rhei, 12 parts in Poria, 12 parts of Radix Angelicae Sinensis, 12 parts of Olibanums, 10 parts of the Radixs Angelicae Dahuricae, 10 parts of Myrrhas, 10 parts of Radix Rehmanniae, 10 parts of Herba Hedyotidis Diffusaes, 10 parts of Radix Arnebiae (Radix Lithospermi)s, 7 parts of the Rhizoma Atractylodis Macrocephalaes, 7 parts of the Radix Paeoniae Albas, 7 parts of Rhizoma Coptidis, 5 parts in Radix Glycyrrhizae, 2 parts of Borneolum Syntheticums, 1 part of Aerugo, 1 part of Calomelas.
Its preparation method may further comprise the steps:
(1) according to described parts by weight weighting raw materials: Radix Codonopsis, Pheretima, Galla Chinensis, Radix Et Rhizoma Rhei, Poria, Radix Angelicae Sinensis, Olibanum, the Radix Angelicae Dahuricae, Myrrha, Radix Rehmanniae, Herba Hedyotidis Diffusae, Radix Arnebiae (Radix Lithospermi), the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Rhizoma Coptidis, Radix Glycyrrhizae, Borneolum Syntheticum, Aerugo, Calomelas are standby;
(2) crude drug that will take by weighing is crushed to the 80-100 order, sterilization, mixing; Make ointment with conventional method.
Embodiment 2:
A kind of external-applied ointment for the treatment of decubital ulcer is made by following bulk drugs: 22 parts of Radix Codonopsis, 22 parts of Pheretimas, 18 parts of Galla Chinensiss, 18 parts of Radix Et Rhizoma Rhei, 10 parts in Poria, 10 parts of Radix Angelicae Sinensis, 10 parts of Olibanums, 9 parts of the Radixs Angelicae Dahuricae, 9 parts of Myrrhas, 9 parts of Radix Rehmanniae, 9 parts of Herba Hedyotidis Diffusaes, 9 parts of Radix Arnebiae (Radix Lithospermi)s, 6 parts of the Rhizoma Atractylodis Macrocephalaes, 6 parts of the Radix Paeoniae Albas, 6 parts of Rhizoma Coptidis, 4 parts in Radix Glycyrrhizae, 1 part of Borneolum Syntheticum, 0.8 part of Aerugo, 0.8 part of Calomelas.
Its preparation method may further comprise the steps:
(1) according to described parts by weight weighting raw materials: Radix Codonopsis, Pheretima, Galla Chinensis, Radix Et Rhizoma Rhei, Poria, Radix Angelicae Sinensis, Olibanum, the Radix Angelicae Dahuricae, Myrrha, Radix Rehmanniae, Herba Hedyotidis Diffusae, Radix Arnebiae (Radix Lithospermi), the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Rhizoma Coptidis, Radix Glycyrrhizae, Borneolum Syntheticum, Aerugo, Calomelas are standby;
(2) crude drug that will take by weighing is crushed to the 80-100 order, sterilization, mixing; Make ointment with conventional method.
Embodiment 3:
A kind of external-applied ointment for the treatment of decubital ulcer is made by following bulk drugs: 28 parts of Radix Codonopsis, 28 parts of Pheretimas, 22 parts of Galla Chinensiss, 22 parts of Radix Et Rhizoma Rhei, 14 parts in Poria, 14 parts of Radix Angelicae Sinensis, 14 parts of Olibanums, 11 parts of the Radixs Angelicae Dahuricae, 11 parts of Myrrhas, 11 parts of Radix Rehmanniae, 11 parts of Herba Hedyotidis Diffusaes, 11 parts of Radix Arnebiae (Radix Lithospermi)s, 8 parts of the Rhizoma Atractylodis Macrocephalaes, 8 parts of the Radix Paeoniae Albas, 8 parts of Rhizoma Coptidis, 6 parts in Radix Glycyrrhizae, 3 parts of Borneolum Syntheticums, 1.2 parts of Aerugo, 1.2 parts of Calomelass.
Its preparation method may further comprise the steps:
(1) according to described parts by weight weighting raw materials: Radix Codonopsis, Pheretima, Galla Chinensis, Radix Et Rhizoma Rhei, Poria, Radix Angelicae Sinensis, Olibanum, the Radix Angelicae Dahuricae, Myrrha, Radix Rehmanniae, Herba Hedyotidis Diffusae, Radix Arnebiae (Radix Lithospermi), the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Rhizoma Coptidis, Radix Glycyrrhizae, Borneolum Syntheticum, Aerugo, Calomelas are standby;
(2) crude drug that will take by weighing is crushed to the 80-100 order, sterilization, mixing; Make ointment with conventional method.
Experimental example:
One, clinical data: adopt the present invention to treat patients with bedsore 28 examples, male 17 examples wherein, women 11 examples, the oldest 81 years old, minimum 27 years old of age.
Two, clinical symptoms: pressurized position erythema, blister, ulcer occur successively; Be more common in paraplegia, the body surface bone knuckle position of long-term chronic consumption illness, large-area burns, degree of depth stupor; Ulcer can reach muscle deeply, invade osteoarthrosis, can move under water around the ulcer lacuna and sinus tract.
Three, Therapeutic Method: conventional method carries out after the debridement treatment this ointment evenly being applied to the decubital ulcer position, and wrapping gets final product; The patient changes dressings once every day; 7 days is a course for the treatment of.
Four, therapeutic evaluation standard:
Cure: the brown erythema disappears, or the wound healing that festers.
Take a turn for the better: erythema does not disappear entirely, or the skin ulcer face slough that festers comes off, granulation, and the skin ulcer face dwindles gradually.
Do not heal: the open sore part increases, and it is more than to fester.
Five, model case:
1, Zheng, the man, 78 years old, suffer from cerebral infarction and hemiplegia, long-term bed causes decubital ulcer, and symptom shows as hip and buttocks festers, has pus, frowziness etc.; The external-applied ointment that uses treatment decubital ulcer of the present invention after 2 courses for the treatment of symptom obviously improve, 4 recoveries from illness courses for the treatment of, wound surface does not have cicatrix and produces, and follows up a case by regular visits to not recurrence in 2 years.
2, Zhao so-and-so, the man, 32 years old, because of paraplegia bed 3 years, cause decubital ulcer then, symptom shows as sacral region a ulcer surface that diameter is about 10 centimetres, is pale asphyxia, and a small amount of secretions etc. is arranged; The external-applied ointment that uses treatment decubital ulcer of the present invention after 2 courses for the treatment of symptom obviously improve, 3 recoveries from illness courses for the treatment of, wound surface does not have cicatrix and produces, and follows up a case by regular visits to not recurrence in 3 years.
Six, therapeutic outcome:
Adopt the present invention to treat patients with bedsore 28 examples, through the treatment of 1-4 the course for the treatment of, wherein cure 25 examples, 3 examples that take a turn for the better, cure rate is 89%, effective percentage is 100%; The result shows, the present invention has the advantage of instant effect, evident in efficacy, preventing from scar.
Claims (3)
1. an external-applied ointment for the treatment of decubital ulcer is characterized in that: made by following bulk drugs: Radix Codonopsis 22-28 part, Pheretima 22-28 part, Galla Chinensis 18-22 part, Radix Et Rhizoma Rhei 18-22 part, Poria 10-14 part, Radix Angelicae Sinensis 10-14 part, Olibanum 10-14 part, Radix Angelicae Dahuricae 9-11 part, Myrrha 9-11 part, Radix Rehmanniae 9-11 part, Herba Hedyotidis Diffusae 9-11 part, Radix Arnebiae (Radix Lithospermi) 9-11 part, Rhizoma Atractylodis Macrocephalae 6-8 part, Radix Paeoniae Alba 6-8 part, Rhizoma Coptidis 6-8 part, Radix Glycyrrhizae 4-6 part, Borneolum Syntheticum 1-3 part, Aerugo 0.8-1.2 part, Calomelas 0.8-1.2 part.
2. the external-applied ointment for the treatment of decubital ulcer according to claim 1 is characterized in that: made by following bulk drugs: 25 parts of Radix Codonopsis, 25 parts of Pheretimas, 20 parts of Galla Chinensiss, 20 parts of Radix Et Rhizoma Rhei, 12 parts in Poria, 12 parts of Radix Angelicae Sinensis, 12 parts of Olibanums, 10 parts of the Radixs Angelicae Dahuricae, 10 parts of Myrrhas, 10 parts of Radix Rehmanniae, 10 parts of Herba Hedyotidis Diffusaes, 10 parts of Radix Arnebiae (Radix Lithospermi)s, 7 parts of the Rhizoma Atractylodis Macrocephalaes, 7 parts of the Radix Paeoniae Albas, 7 parts of Rhizoma Coptidis, 5 parts in Radix Glycyrrhizae, 2 parts of Borneolum Syntheticums, 1 part of Aerugo, 1 part of Calomelas.
3. the preparation method of the external-applied ointment for the treatment of decubital ulcer according to claim 1 and 2 may further comprise the steps:
(1) according to described parts by weight weighting raw materials: Radix Codonopsis, Pheretima, Galla Chinensis, Radix Et Rhizoma Rhei, Poria, Radix Angelicae Sinensis, Olibanum, the Radix Angelicae Dahuricae, Myrrha, Radix Rehmanniae, Herba Hedyotidis Diffusae, Radix Arnebiae (Radix Lithospermi), the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Rhizoma Coptidis, Radix Glycyrrhizae, Borneolum Syntheticum, Aerugo, Calomelas are standby;
(2) crude drug that will take by weighing is crushed to the 80-100 order, sterilization, mixing; Make ointment with conventional method.
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| CN103690698A (en) * | 2013-11-26 | 2014-04-02 | 安徽三超药业有限公司 | Broad-spectrum antibacterial cream |
| CN103920022A (en) * | 2014-04-30 | 2014-07-16 | 济宁市第一人民医院 | Traditional Chinese medicine composition for treating bedsores and using method thereof |
| CN104491630A (en) * | 2014-12-05 | 2015-04-08 | 山东省立医院 | Traditional Chinese medicine for treating bedsores and preparation method thereof |
| CN104547634A (en) * | 2014-12-25 | 2015-04-29 | 广东聚智诚科技有限公司 | Application of traditional Chinese medicinal composition for preparing medicine for treating bedsore |
| CN105435133A (en) * | 2016-01-22 | 2016-03-30 | 青岛华之草医药科技有限公司 | Method for preparing traditional Chinese medicine preparation for treating bedsore |
| CN105456953A (en) * | 2016-01-22 | 2016-04-06 | 青岛华之草医药科技有限公司 | Traditional Chinese medicine preparation for treating bedsore |
| CN105535335A (en) * | 2016-02-26 | 2016-05-04 | 许诚章 | Plaster for treating ulcer of lower limbs |
| CN105796744A (en) * | 2016-03-29 | 2016-07-27 | 李绍斌 | Toxin-removal traditional Chinese medicine ointment |
| CN107050237A (en) * | 2017-01-10 | 2017-08-18 | 利川市民族中医院 | A kind of plaster of external application for curing bedsore |
| CN110123936A (en) * | 2019-06-21 | 2019-08-16 | 烟台了神医疗器械有限公司 | A kind of Chinese materia medica preparation and preparation method thereof for treating bedsore |
| CN110882310A (en) * | 2019-12-24 | 2020-03-17 | 河南生命圈中医药研究院(有限合伙) | Sore surface repairing paste and preparation method thereof |
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| CN102302677A (en) * | 2011-08-29 | 2012-01-04 | 陈德素 | Burn and scald liquid, burn and scald ointment, and preparation method thereof |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103690698A (en) * | 2013-11-26 | 2014-04-02 | 安徽三超药业有限公司 | Broad-spectrum antibacterial cream |
| CN103920022A (en) * | 2014-04-30 | 2014-07-16 | 济宁市第一人民医院 | Traditional Chinese medicine composition for treating bedsores and using method thereof |
| CN104491630A (en) * | 2014-12-05 | 2015-04-08 | 山东省立医院 | Traditional Chinese medicine for treating bedsores and preparation method thereof |
| CN104547634A (en) * | 2014-12-25 | 2015-04-29 | 广东聚智诚科技有限公司 | Application of traditional Chinese medicinal composition for preparing medicine for treating bedsore |
| CN104547634B (en) * | 2014-12-25 | 2017-09-22 | 广东聚智诚科技有限公司 | A kind of purposes of Chinese medicine composition in treatment bedsore medicine is prepared |
| CN105435133A (en) * | 2016-01-22 | 2016-03-30 | 青岛华之草医药科技有限公司 | Method for preparing traditional Chinese medicine preparation for treating bedsore |
| CN105456953A (en) * | 2016-01-22 | 2016-04-06 | 青岛华之草医药科技有限公司 | Traditional Chinese medicine preparation for treating bedsore |
| CN105535335A (en) * | 2016-02-26 | 2016-05-04 | 许诚章 | Plaster for treating ulcer of lower limbs |
| CN105796744A (en) * | 2016-03-29 | 2016-07-27 | 李绍斌 | Toxin-removal traditional Chinese medicine ointment |
| CN107050237A (en) * | 2017-01-10 | 2017-08-18 | 利川市民族中医院 | A kind of plaster of external application for curing bedsore |
| CN110123936A (en) * | 2019-06-21 | 2019-08-16 | 烟台了神医疗器械有限公司 | A kind of Chinese materia medica preparation and preparation method thereof for treating bedsore |
| CN110882310A (en) * | 2019-12-24 | 2020-03-17 | 河南生命圈中医药研究院(有限合伙) | Sore surface repairing paste and preparation method thereof |
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| CN103272053B (en) | 2014-10-15 |
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