CN104147209A - Medicine for treating chronic pelvic inflammatory disease and application thereof - Google Patents
Medicine for treating chronic pelvic inflammatory disease and application thereof Download PDFInfo
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- CN104147209A CN104147209A CN201410424818.6A CN201410424818A CN104147209A CN 104147209 A CN104147209 A CN 104147209A CN 201410424818 A CN201410424818 A CN 201410424818A CN 104147209 A CN104147209 A CN 104147209A
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Abstract
The invention relates to a medicine for treating chronic pelvic inflammatory disease. The medicine is prepared from following raw material medicines comprising, by weight, 15-25 parts of sargentodoxa cuneata, 10-20 parts of thlaspi arvense, 7-13 parts of poria cocos, 10-20 parts of heartleaf houttuynia herbs, 15-25 parts of purslane, 10-20 parts of dandelion, 4-8 parts of white peony roots, 7-13 parts of angelica sinensis, 4-8 parts of rhizoma chuanxiong and 4-8 parts of mix-fried radix glycyrrhizae. The invention also relates to an application of the medicine in treatment of the chronic pelvic inflammatory disease. The medicine is mainly used in treatment of the chronic pelvic inflammatory disease and damp heat and blood stasis with heat clearing and dampness dispelling as interior and qi regulating and stasis dispelling as exterior, allows damp heat, blood stasis and qi stagnation to be considered and has functions of activating blood without damaging healthy qi, resolving dampness and clearing heat and dispelling stasis and relieving pain.
Description
Technical field
The present invention relates to the field of Chinese medicines, specifically, is a kind of medicine and application thereof for the treatment of chronic pelvic inflammatory disease.
Background technology
Chronic pelvic inflammatory disease refers to the inflammation of the interior reproductive tract of women and surrounding tissue thereof, comprise salpingitis, endometritis, tubo-ovarian abscess, majority occurs in sexual life active phase, generally by acute inflammation treatment lack of standardization, repeated multiple times infection forms, often prolongedly do not heal, chronic delay, concurrent infertile, metacyesis, have a strong impact on women's health, increase family and social economical burden, use merely the western medicine untoward reaction such as antimicrobial drug many, be prone to bacterial resistance, the curative effect of medicine is declined, make treatment be difficult to adhere to, curative effect is poor.Because primary disease is common gynecological disease, frequently-occurring disease, be apt to occur in Women of Childbearing Age, and the course of disease is long, cure rate is low, sickness rate rises gradually in recent years.Without definite effectively Therapeutic Method, chronic pelvic inflammatory disease is prolonged not to heal at present, outbreak repeatedly, and the traditional Chinese medical science is really characteristic aspect the treatment of pelvic inflammatory disease, is also a trend of our current pelvic inflammatory disease treatment.
Motherland's medical science, but sporadically appears in " invasion of the blood-chamber by heat " about the discussion of pelvic inflammatory disease without special discussion to pelvic inflammatory disease, in the diseases such as " leukorrheal diseases ", " through sick pain ", " married woman's stomachache ", " infertile ".The traditional Chinese medical science thinks that mostly the generation of primary disease is that pathogenic heat enter uterus and blood is tied retardance vessels of the uterus mutually due in the vessels of the uterus inanitions such as row puerperal, and it is not smooth to cause vessels of the uterus QI-blood circulation, stops up in the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, accumulates and heat-transformation, is one of gynecological's common disease.The rule for the treatment of be take clearing away heat-damp and promoting diuresis, activating blood circulation to dissipate blood stasis as main, is aided with the methods such as dispelling cold by warming the meridian, promoting flow of QI and blood, QI invigorating damp eliminating.Pelvic inflammatory disease is a state of an illness stubbornness, outbreak repeatedly, the difficult disease healing of delay.Some patient passes through various treatments often, does not prolongedly heal.Chinese traditional treatment primary disease combines with dialectical with differential diagnosis of diseases.Pelvic inflammatory disease is in the majority with damp-heat accumulation, and minority has QI stagnated by cold type, deficiency of vital energy damp-obstruction type.This sick western medical treatment be take antibiotic as main at present, but its treatment time is long, consumes greatly, takes effect few, easily produces drug resistance.
Therefore develop a kind of curative effect obvious, instant effect, cheap, the medicine of the treatment chronic pelvic inflammatory disease having no side effect is very necessary.
Summary of the invention
The object of the invention is for deficiency of the prior art, a kind of medicine for the treatment of chronic pelvic inflammatory disease is provided.
One object more of the present invention is that described medicine is treated the application in chronic pelvic inflammatory disease medicine in preparation.
For achieving the above object, the technical scheme that the present invention takes is:
Treat a medicine for chronic pelvic inflammatory disease, it is to be made by the crude drug of following weight portion: 15 ~ 25 parts of Caulis Sargentodoxaes, 10 ~ 20 parts of Herba Patriniae, 7 ~ 13 parts, Poria, 10 ~ 20 parts of Herba Houttuyniae, 15 ~ 25 parts of Herba Portulacaes, 10 ~ 20 parts of Herba Taraxacis, 4 ~ 8 parts of Radix Paeoniae Alba, 7 ~ 13 parts of Radix Angelicae Sinensis, 4 ~ 8 parts of Rhizoma Chuanxiongs, 4 ~ 8 parts of Radix Glycyrrhizae Preparatas.
Described medicine is to be made by the crude drug of following weight portion: 18 ~ 22 parts of Caulis Sargentodoxaes, 13 ~ 17 parts of Herba Patriniae, 9 ~ 11 parts, Poria, 13 ~ 17 parts of Herba Houttuyniae, 18 ~ 22 parts of Herba Portulacaes, 13 ~ 17 parts of Herba Taraxacis, 5 ~ 7 parts of Radix Paeoniae Alba, 9 ~ 11 parts of Radix Angelicae Sinensis, 5 ~ 7 parts of Rhizoma Chuanxiongs, 5 ~ 7 parts of Radix Glycyrrhizae Preparatas.
Described medicine is to be made by the crude drug of following weight portion: 20 parts of Caulis Sargentodoxaes, 15 parts of Herba Patriniae, 10 parts, Poria, 15 parts of Herba Houttuyniae, 20 parts of Herba Portulacaes, 15 parts of Herba Taraxacis, 6 parts of Radix Paeoniae Alba, 10 parts of Radix Angelicae Sinensis, 6 parts of Rhizoma Chuanxiongs, 6 parts of Radix Glycyrrhizae Preparatas.
The medicament of described medicine is capsule, granule, tablet, oral liquid, mixture or syrup.
For realizing above-mentioned second object, the technical scheme that the present invention takes is:
The application of described medicine in preparation treatment chronic pelvic inflammatory disease medicine.
Described chronic pelvic inflammatory disease is Accumulation of Dampness Heat and Blood Stasis type chronic pelvic inflammatory disease.
Medicine of the present invention is mainly used in the treatment of Accumulation of Dampness Heat and Blood Stasis type of chronic pelvic inflammatory disease, has heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, hard masses softening and resolving, an effect of the Disorder evacuation of pus that disappears.
Monarch drug: Caulis Sargentodoxae, Herba Patriniae, Herba Taraxaci, Herba Portulacae, Herba Houttuyniae.
Caulis Sargentodoxae heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, modern pharmacological research shows that Caulis Sargentodoxae all has obvious sterilization and inhibitory action to various bacteria such as staphylococcus aureus and group B streptococcus, Herba Patriniae heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, stasis-dispelling and pain-killing, Herba Houttuyniae heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, inducing diuresis for treating stranguria syndrome, Herba Taraxaci heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, dampness removing is treating stranguria, Herba Portulacae heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, Herba Patriniae, Herba Taraxaci, Herba Houttuyniae all has certain sterilization and bacteriostasis effect to gram positive bacteria and negative bacterium, can increase skein cell and leukocytic volume and bite ability, improve body anti-infection ability, enhancing antibody forms and improves Lysozyme Levels in serum, from to reaching antibacterial and anti-inflammation functions.Modern pharmacological research is verified, and these medical instruments have antibacterial widely, bacteriostasis, and can promote pelvic cavity local blood circulation, and improve and organize oxygen supply and nutrition supply, promote inflammation to ooze out and absorb and disappearing of inflammatory lesions tissue and softening of proliferative lesion tissue.So five medicine heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus are principal agent.
Ministerial drug: Radix Angelicae Sinensis, Rhizoma Chuanxiong.
Chronic pelvic inflammation many because of puerperal, through after, uterus inanition, noxious dampness and the damp and hot intrusions such as heresy, and QI and blood ties mutually in vessels of the uterus, uterus and stagnation of QI-blood, punching and appoints and be obstructed, and is condensed into disease, qi depression to blood stasis, abdomen flow of QI being obstructed, stagnation of QI and blood may bring about pain and falling ill.The traditional Chinese medical science thinks that prolonged illness must the stasis of blood, and how wet prolonged illness is, and therefore, on the basis of determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, when using heat and toxic materials clearing away medicine, must take into account prolonged illness must have this feature of the stasis of blood, therefore add Radix Angelicae Sinensis, Rhizoma Chuanxiong two medicines in this side.
Radix Angelicae Sinensis taste sweet, acrid, warm.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, is gynecological's key medicine, and modern pharmacological research shows that Radix Angelicae Sinensis has Biphasic Regulation, has anti-platelet aggregation and anti thrombotic action, improves peripheral circulation, has in addition the effects such as analgesia, antiinflammatory, anti-hypoxia and in-vitro antibacterial.Rhizoma Chuanxiong acrid in the mouth is warm in nature, returns liver, gallbladder, pericardium channel; Effect is blood-activating and qi-promoting, wind-expelling pain-stopping.< < book on Chinese herbal medicine guiding principle day > >: " in (Rhizoma Chuanxiong) blood, gas medicine also ... pungent to fall apart it, therefore stagnation of QI person should it." < < book on Chinese herbal medicine remittance speech > >: " (Rhizoma Chuanxiong), the up head, lower regulating menstruation water, middle relieving stagnation, in blood, gas approximately, is often made by Radix Angelicae Sinensis, Fei Zhi blood is meritorious, and control gas also god test also, modern pharmacological research shows, the water decoction of Rhizoma Chuanxiong has inhibitory action to escherichia coli, bacillus pyocyaneus etc.This two medicines compatibility, the merit of playing altogether blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain, " qi as the commander of blood ", " the capable blood of gas ", so two medicines are ministerial drug altogether.
Adjuvant drug: Poria, Radix Paeoniae Alba.
Poria is sweet, light, flat.GUIXIN, spleen, kidney channel, have the effect of promoting diuresis to eliminate damp pathogen, spleen-benefiting mind-tranquilizing, and sweet the providing additional supplies of this product oozed, and the flat effect of property relaxes, and in this side, plays invigorating spleen to remove dampness, inflammation osmosis, and to relax the strong of principal agent be adjuvant drug.Radix Paeoniae Alba easing the affected liver to relieve pain, supervises the pungent perfume (or spice) of Rhizoma Chuanxiong and walks to alter at this Fang Zhongke, two medicines are adjuvant drug altogether.
Make medicine: Radix Glycyrrhizae Preparata.
Radix Glycyrrhizae Preparata: sweet, flat.GUIXIN, lung, spleen, stomach warp, have the effect of QI invigorating invigorating middle warmer, removing toxic substances, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, and this medicine is placed on and in this side, has been in harmonious proportion the strong of all medicines, and QI invigorating regulating the spleen and stomach, for making medicine.
The effect that full side plays clearing heat and expelling damp, blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain altogether, take clearing heat and expelling damp as it, and regulating the flow of QI to dissipate blood stasis is controlled its mark.Take into account damp and hot, blood stasis, stagnation of QI tripartite and, can reach invigorates blood circulation does not just hinder, removing dampness heat clearing away, the effect of stasis-dispelling and pain-killing, thus catch the leading pathogenesis of primary disease, reach and attack standby taking into account, not only alleviated the painful of patient and had no side effect.
Make a general survey of this side, take heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus as main be this, blood circulation promoting and blood stasis dispelling, dampness removing pain relieving be auxiliary be mark, take into account damp and hot, the stagnation of QI, blood stasis three aspects:, and add taste in conjunction with clinical syndrome differentiation, reach removing dampness heat clearing away, the effect of stasis-dispelling and pain-killing.
The invention has the advantages that:
1, medicine of the present invention be take clearing heat and expelling damp as it, and regulating the flow of QI to dissipate blood stasis is controlled its mark.Take into account damp and hot, blood stasis, stagnation of QI tripartite, can reach invigorates blood circulation does not just hinder, removing dampness heat clearing away, the effect of stasis-dispelling and pain-killing.Its compatibility is precise and appropriate, evident in efficacy.
2, drug price of the present invention is cheap, short treating period, and curative effect is fast.
The specific embodiment
Below the specific embodiment provided by the invention is elaborated.
the preparation (one) of embodiment 1 treatment chronic pelvic inflammatory disease medicine
15 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 7 parts, Poria, 10 parts of Herba Houttuyniae, 15 parts of Herba Portulacaes, 10 parts of Herba Taraxacis, 4 parts of Radix Paeoniae Alba, 7 parts of Radix Angelicae Sinensis, 4 parts of Rhizoma Chuanxiongs, 4 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (two) of embodiment 2 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 7 parts, Poria, 10 parts of Herba Houttuyniae, 15 parts of Herba Portulacaes, 10 parts of Herba Taraxacis, 4 parts of Radix Paeoniae Alba, 7 parts of Radix Angelicae Sinensis, 4 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (three) of embodiment 3 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 7 parts, Poria, 10 parts of Herba Houttuyniae, 15 parts of Herba Portulacaes, 10 parts of Herba Taraxacis, 4 parts of Radix Paeoniae Alba, 7 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (four) of embodiment 4 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 7 parts, Poria, 10 parts of Herba Houttuyniae, 15 parts of Herba Portulacaes, 10 parts of Herba Taraxacis, 4 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (five) of embodiment 5 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 7 parts, Poria, 10 parts of Herba Houttuyniae, 15 parts of Herba Portulacaes, 10 parts of Herba Taraxacis, 8 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (six) of embodiment 6 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 7 parts, Poria, 10 parts of Herba Houttuyniae, 15 parts of Herba Portulacaes, 20 parts of Herba Taraxacis, 8 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (seven) of embodiment 7 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 7 parts, Poria, 10 parts of Herba Houttuyniae, 25 parts of Herba Portulacaes, 20 parts of Herba Taraxacis, 8 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (eight) of embodiment 8 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 7 parts, Poria, 20 parts of Herba Houttuyniae, 25 parts of Herba Portulacaes, 20 parts of Herba Taraxacis, 8 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (nine) of embodiment 9 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 13 parts, Poria, 20 parts of Herba Houttuyniae, 25 parts of Herba Portulacaes, 20 parts of Herba Taraxacis, 8 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (ten) of embodiment 10 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 20 parts of Herba Patriniae, 13 parts, Poria, 20 parts of Herba Houttuyniae, 25 parts of Herba Portulacaes, 20 parts of Herba Taraxacis, 8 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (11) of embodiment 11 treatment chronic pelvic inflammatory disease medicines
25 parts of Caulis Sargentodoxaes, 20 parts of Herba Patriniae, 13 parts, Poria, 20 parts of Herba Houttuyniae, 25 parts of Herba Portulacaes, 20 parts of Herba Taraxacis, 8 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (12) of embodiment 12 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 20 parts of Herba Patriniae, 7 parts, Poria, 20 parts of Herba Houttuyniae, 15 parts of Herba Portulacaes, 20 parts of Herba Taraxacis, 4 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 4 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (13) of embodiment 13 treatment chronic pelvic inflammatory disease medicines
25 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 13 parts, Poria, 10 parts of Herba Houttuyniae, 25 parts of Herba Portulacaes, 10 parts of Herba Taraxacis, 8 parts of Radix Paeoniae Alba, 7 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 4 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (14) of embodiment 14 treatment chronic pelvic inflammatory disease medicines
20 parts of Caulis Sargentodoxaes, 15 parts of Herba Patriniae, 10 parts, Poria, 15 parts of Herba Houttuyniae, 20 parts of Herba Portulacaes, 15 parts of Herba Taraxacis, 6 parts of Radix Paeoniae Alba, 10 parts of Radix Angelicae Sinensis, 6 parts of Rhizoma Chuanxiongs, 6 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (15) of embodiment 15 treatment chronic pelvic inflammatory disease medicines
20 parts of Caulis Sargentodoxaes, 20 parts of Herba Patriniae, 7 parts, Poria, 20 parts of Herba Houttuyniae, 15 parts of Herba Portulacaes, 20 parts of Herba Taraxacis, 4 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 4 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (16) of embodiment 16 treatment chronic pelvic inflammatory disease medicines
25 parts of Caulis Sargentodoxaes, 15 parts of Herba Patriniae, 13 parts, Poria, 10 parts of Herba Houttuyniae, 25 parts of Herba Portulacaes, 10 parts of Herba Taraxacis, 8 parts of Radix Paeoniae Alba, 7 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 4 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (17) of embodiment 17 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 20 parts of Herba Patriniae, 10 parts, Poria, 20 parts of Herba Houttuyniae, 15 parts of Herba Portulacaes, 20 parts of Herba Taraxacis, 4 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 4 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (18) of embodiment 18 treatment chronic pelvic inflammatory disease medicines
25 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 13 parts, Poria, 15 parts of Herba Houttuyniae, 25 parts of Herba Portulacaes, 10 parts of Herba Taraxacis, 8 parts of Radix Paeoniae Alba, 7 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 4 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (19) of embodiment 19 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 20 parts of Herba Patriniae, 7 parts, Poria, 20 parts of Herba Houttuyniae, 20 parts of Herba Portulacaes, 20 parts of Herba Taraxacis, 4 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 4 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (20) of embodiment 20 treatment chronic pelvic inflammatory disease medicines
25 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 13 parts, Poria, 10 parts of Herba Houttuyniae, 25 parts of Herba Portulacaes, 15 parts of Herba Taraxacis, 8 parts of Radix Paeoniae Alba, 7 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 4 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (21) of embodiment 21 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 20 parts of Herba Patriniae, 7 parts, Poria, 20 parts of Herba Houttuyniae, 15 parts of Herba Portulacaes, 20 parts of Herba Taraxacis, 6 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 4 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (22) of embodiment 22 treatment chronic pelvic inflammatory disease medicines
25 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 13 parts, Poria, 10 parts of Herba Houttuyniae, 25 parts of Herba Portulacaes, 10 parts of Herba Taraxacis, 8 parts of Radix Paeoniae Alba, 10 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 4 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (23) of embodiment 23 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 20 parts of Herba Patriniae, 7 parts, Poria, 20 parts of Herba Houttuyniae, 15 parts of Herba Portulacaes, 20 parts of Herba Taraxacis, 4 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 4 parts of Rhizoma Chuanxiongs, 6 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (24) of embodiment 24 treatment chronic pelvic inflammatory disease medicines
25 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 13 parts, Poria, 10 parts of Herba Houttuyniae, 25 parts of Herba Portulacaes, 10 parts of Herba Taraxacis, 8 parts of Radix Paeoniae Alba, 7 parts of Radix Angelicae Sinensis, 6 parts of Rhizoma Chuanxiongs, 4 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (25) of embodiment 25 treatment chronic pelvic inflammatory disease medicines
20 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 7 parts, Poria, 10 parts of Herba Houttuyniae, 15 parts of Herba Portulacaes, 10 parts of Herba Taraxacis, 4 parts of Radix Paeoniae Alba, 7 parts of Radix Angelicae Sinensis, 4 parts of Rhizoma Chuanxiongs, 4 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (26) of embodiment 26 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 15 parts of Herba Patriniae, 7 parts, Poria, 10 parts of Herba Houttuyniae, 15 parts of Herba Portulacaes, 10 parts of Herba Taraxacis, 4 parts of Radix Paeoniae Alba, 7 parts of Radix Angelicae Sinensis, 4 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (27) of embodiment 27 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 10 parts, Poria, 10 parts of Herba Houttuyniae, 15 parts of Herba Portulacaes, 10 parts of Herba Taraxacis, 4 parts of Radix Paeoniae Alba, 7 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (28) of embodiment 28 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 7 parts, Poria, 15 parts of Herba Houttuyniae, 15 parts of Herba Portulacaes, 10 parts of Herba Taraxacis, 4 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (29) of embodiment 29 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 7 parts, Poria, 10 parts of Herba Houttuyniae, 20 parts of Herba Portulacaes, 10 parts of Herba Taraxacis, 8 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (30) of embodiment 30 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 7 parts, Poria, 10 parts of Herba Houttuyniae, 15 parts of Herba Portulacaes, 15 parts of Herba Taraxacis, 8 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (31) of embodiment 31 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 7 parts, Poria, 10 parts of Herba Houttuyniae, 25 parts of Herba Portulacaes, 20 parts of Herba Taraxacis, 6 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (32) of embodiment 32 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 7 parts, Poria, 20 parts of Herba Houttuyniae, 25 parts of Herba Portulacaes, 20 parts of Herba Taraxacis, 8 parts of Radix Paeoniae Alba, 10 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (33) of embodiment 33 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 10 parts of Herba Patriniae, 13 parts, Poria, 20 parts of Herba Houttuyniae, 25 parts of Herba Portulacaes, 20 parts of Herba Taraxacis, 8 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 6 parts of Rhizoma Chuanxiongs, 8 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (34) of embodiment 34 treatment chronic pelvic inflammatory disease medicines
15 parts of Caulis Sargentodoxaes, 20 parts of Herba Patriniae, 13 parts, Poria, 20 parts of Herba Houttuyniae, 25 parts of Herba Portulacaes, 20 parts of Herba Taraxacis, 8 parts of Radix Paeoniae Alba, 13 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 6 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (35) of embodiment 35 treatment chronic pelvic inflammatory disease medicines
17 parts of Caulis Sargentodoxaes, 12 parts of Herba Patriniae, 9 parts, Poria, 12 parts of Herba Houttuyniae, 17 parts of Herba Portulacaes, 12 parts of Herba Taraxacis, 5 parts of Radix Paeoniae Alba, 9 parts of Radix Angelicae Sinensis, 5 parts of Rhizoma Chuanxiongs, 5 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (36) of embodiment 36 treatment chronic pelvic inflammatory disease medicines
22 parts of Caulis Sargentodoxaes, 17 parts of Herba Patriniae, 11 parts, Poria, 17 parts of Herba Houttuyniae, 22 parts of Herba Portulacaes, 17 parts of Herba Taraxacis, 7 parts of Radix Paeoniae Alba, 12 parts of Radix Angelicae Sinensis, 7 parts of Rhizoma Chuanxiongs, 7 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (37) of embodiment 37 treatment chronic pelvic inflammatory disease medicines
11 parts of Caulis Sargentodoxaes, 19 parts of Herba Patriniae, 12 parts, Poria, 11 parts of Herba Houttuyniae, 24 parts of Herba Portulacaes, 14 parts of Herba Taraxacis, 7 parts of Radix Paeoniae Alba, 8 parts of Radix Angelicae Sinensis, 7 parts of Rhizoma Chuanxiongs, 7 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (38) of embodiment 38 treatment chronic pelvic inflammatory disease medicines
14 parts of Caulis Sargentodoxaes, 14 parts of Herba Patriniae, 8 parts, Poria, 18 parts of Herba Houttuyniae, 21 parts of Herba Portulacaes, 16 parts of Herba Taraxacis, 7 parts of Radix Paeoniae Alba, 12 parts of Radix Angelicae Sinensis, 7 parts of Rhizoma Chuanxiongs, 7 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (39) of embodiment 39 treatment chronic pelvic inflammatory disease medicines
24 parts of Caulis Sargentodoxaes, 14 parts of Herba Patriniae, 7 parts, Poria, 19 parts of Herba Houttuyniae, 21 parts of Herba Portulacaes, 18 parts of Herba Taraxacis, 7 parts of Radix Paeoniae Alba, 12 parts of Radix Angelicae Sinensis, 7 parts of Rhizoma Chuanxiongs, 7 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
the preparation (40) of embodiment 40 treatment chronic pelvic inflammatory disease medicines
24 parts of Caulis Sargentodoxaes, 17 parts of Herba Patriniae, 19 parts, Poria, 15 parts of Herba Houttuyniae, 21 parts of Herba Portulacaes, 19 parts of Herba Taraxacis, 7 parts of Radix Paeoniae Alba, 8 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiongs, 7 parts of Radix Glycyrrhizae Preparatas, conventional method decocts.
It should be noted that, it is the manufacture method of Chinese medicine decoction routine that the conventional method described in embodiment 1-40 decocts, and is about to described crude drug and decocts with water into decoction.
the preparation of embodiment 41 treatment chronic pelvic inflammatory disease medicinal tablet/capsules
Get the arbitrary described medicine of embodiment 1-40, add 8-12 times of water gaging, decoct 1-3 hour, leach medicine juice.Add again 10 times of water gagings, decoct 1.5-2.5 hour, leach medicine juice, merge secondary decocting liquid, standing, leaching supernatant, concentrated, let cool, add 2.5 times of amount ethanol of concentrated solution, stir precipitation and spend the night.Get supernatant, be concentrated into thick extractum; Add pharmaceutical aids, vacuum drying, pulverizes and granulates, and is pressed into tablet or fills encapsulated.
the preparation of embodiment 42 treatment chronic pelvic inflammatory disease drug particles
Get the arbitrary described medicine of embodiment 1-40, add 8-10 times of water gaging, decoct 2.5-3.5 hour, leach medicine juice.Add again 10 times of water gagings, decoct 2 hours, leach medicine juice, merge secondary decocting liquid, standing, leaching supernatant, concentrated, let cool, add 2 times of amount ethanol of concentrated solution, stir precipitation and spend the night.Get supernatant, be concentrated into thick extractum; Add suitable pharmaceutical aids, granulate, dry, granulate, obtains 20g granule, subpackage 10g/ bag.
the preparation of embodiment 43 treatment chronic pelvic inflammatory disease drug mixture/oral liquid/syrups
Get the arbitrary described medicine of embodiment 1-40, add 8-10 times of water gaging, decoct 3 hours, leach medicine juice.Add again 8 times of water gagings, decoct 2 hours, leach medicine juice, merge secondary decocting liquid, standing, leaching supernatant, concentrated, let cool, add 2 times of amount ethanol of concentrated solution, stir precipitation and spend the night.Get supernatant, be concentrated into thick extractum; Add suitable pharmaceutical aids, make mixture, oral liquid or syrup.
embodiment 44 treatment chronic pelvic inflammatory disease curative effect of medication experiments
1, case selection
Accumulation of Dampness Heat and Blood Stasis type Patients with Pelvic Inflammatory Disease 270 examples of selecting Wo Yuanhuo outer court to make a definite diagnosis are observed, and patient is divided into three groups at random.Treatment group 90 examples, age 25-60 year, 33.6 years old mean age.Matched group one 90 examples, age 24-61 year, 34.8 years old mean age.Matched group 2 90 examples, age 24-59 year, 33.8 years old mean age.Three groups of patient's physical data are learned processing by statistics, compare between two difference there are no significant meaning (p>0.05), have comparability.
2, diagnostic criteria
Western medicine diagnose standard: (1) has acute pelvic inflammatory disease history; (2) lower abdomen pendant rises, pain and lumbosacral aching pain, aggravation before and after the fatigue of being everlasting, sexual intercourse and menstruation; (3) vaginal discharge; (4) fundus of uterus tenderness and uterus one side or bilateral touch streak enclosed mass; (5) ultrasonic examination can spy and abnormal echo or irregular dark space or uterus rectum is recessed a hydrops; (6) disease such as pelvic congestion or the varicose of broad ligament angular vein except.
Standards of Chinese Medical Syndrome Differentiation: inferior belly gas pain or twinge, sore spot is fixed, and waist sacrum goes up painful, profuse leukorrhea, yellow skin taste is smelly.Inferior disease shows as: spiritlessness and weakness, and low thermal fluctuation, uncomfortable in chest indigestion and loss of appetite, menorrhagia or companion's menostaxis, abdominal pain in menstruation increases the weight of, and yellow urine is hard and dry or half congealed and not well.Tongue arteries and veins mostly is redness or kermesinus, and petechia or ecchymosis are seen in tongue limit.
3, Therapeutic Method
Treatment group is taken the medicine of embodiment 14 preparation, decocts to concentration as containing crude drug amount 0.35g/mL, and decoction being taken warmly after meal, each 1 dose sooner or later of every day, every dose is 200ml.Matched group one is taken the medicine of 20 parts of Caulis Sargentodoxaes, 15 parts of Herba Patriniae, 10 parts, Poria, 15 parts of Herba Houttuyniae, 20 parts of Herba Portulacaes, 15 parts of Herba Taraxacis, 6 parts of Radix Paeoniae Alba, 10 parts of Radix Angelicae Sinensis, 6 parts of Olibanums, 6 parts of preparations of Radix Glycyrrhizae Preparata, decoct to concentration as containing crude drug amount 0.31g/mL, decoction being taken warmly after meal, each 1 dose sooner or later of every day, every dose is 200ml.Matched group two is taken FULE KELI, sooner or later respectively take 2 bags, FULE KELI is the comparatively sure medicine of current curative effect, the FULE KELI that the present embodiment is used is produced by Xiangfan grand Chinese medicinal material industry Co., Ltd, authentication code: the accurate word Z42020643 of traditional Chinese medicines, its specification is: 6g/ bag, main component: Caulis Lonicerae, Caulis Sargentodoxae, Folium Isatidis, Radix Et Rhizoma Rhei, Herba Taraxaci, Radix Paeoniae Rubra, Du's Cortex Moutan, Fructus Toosendan, Rhizoma Corydalis, Radix Glycyrrhizae.All take medicine continuously 6 weeks for three groups, cure case and follow up a case by regular visits to after one month.
4, criterion of therapeutical effect
Cure: clinical symptoms, sign disappear, gynecological and ultrasonic examination report show no obvious abnormalities;
Effective: clinical symptoms, sign and gynecological and ultrasonicly all have and alleviate;
Invalid: clinical symptoms, sign and gynecological and ultrasonic examination are all not improved.
5, therapeutic outcome
In treatment group, cure 81 examples, effective 5 examples, invalid 4 examples, cure rate 90%, effective percentage 95.6%.
In matched group one, cure 54 examples, effective 8 examples, invalid 28 examples, cure rate 60%, effective percentage 68.9%.
In matched group two, cure 51 examples, effective 19 examples, invalid 20 examples, cure rate 56.7%, effective percentage 77.8%.Three groups of obvious effective rates are compared between two, all have significant difference (P<0.05); Three groups of effective percentage are compared between two, all have significant difference (P<0.05).
In sum, by this clinical experiment, observe visible, the effect of Drug therapy Accumulation of Dampness Heat and Blood Stasis card chronic pelvic inflammatory disease of the present invention is better than existing market common drug, clearing heat and expelling damp, regulating the flow of QI to dissipate blood stasis, takes into account damp and hot, blood stasis, stagnation of QI tripartite, and can reach invigorates blood circulation does not just hinder, removing dampness heat clearing away, the effect of stasis-dispelling and pain-killing.
The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, do not departing under the prerequisite of the inventive method; can also make some improvement and supplement, these improvement and supplement and also should be considered as protection scope of the present invention.
Claims (6)
1. a medicine for the treatment of chronic pelvic inflammatory disease, it is characterized in that, it is to be made by the crude drug of following weight portion: 15 ~ 25 parts of Caulis Sargentodoxaes, 10 ~ 20 parts of Herba Patriniae, 7 ~ 13 parts, Poria, 10 ~ 20 parts of Herba Houttuyniae, 15 ~ 25 parts of Herba Portulacaes, 10 ~ 20 parts of Herba Taraxacis, 4 ~ 8 parts of Radix Paeoniae Alba, 7 ~ 13 parts of Radix Angelicae Sinensis, 4 ~ 8 parts of Rhizoma Chuanxiongs, 4 ~ 8 parts of Radix Glycyrrhizae Preparatas.
2. medicine according to claim 1, it is characterized in that, it is to be made by the crude drug of following weight portion: 18 ~ 22 parts of Caulis Sargentodoxaes, 13 ~ 17 parts of Herba Patriniae, 9 ~ 11 parts, Poria, 13 ~ 17 parts of Herba Houttuyniae, 18 ~ 22 parts of Herba Portulacaes, 13 ~ 17 parts of Herba Taraxacis, 5 ~ 7 parts of Radix Paeoniae Alba, 9 ~ 11 parts of Radix Angelicae Sinensis, 5 ~ 7 parts of Rhizoma Chuanxiongs, 5 ~ 7 parts of Radix Glycyrrhizae Preparatas.
3. medicine according to claim 1, it is characterized in that, it is to be made by the crude drug of following weight portion: 20 parts of Caulis Sargentodoxaes, 15 parts of Herba Patriniae, 10 parts, Poria, 15 parts of Herba Houttuyniae, 20 parts of Herba Portulacaes, 15 parts of Herba Taraxacis, 6 parts of Radix Paeoniae Alba, 10 parts of Radix Angelicae Sinensis, 6 parts of Rhizoma Chuanxiongs, 6 parts of Radix Glycyrrhizae Preparatas.
4. according to the arbitrary described medicine of claim 1-3, it is characterized in that, the medicament of described medicine is capsule, granule, tablet, oral liquid, mixture or syrup.
5. the application of the arbitrary described medicine of claims 1-3 in preparation treatment chronic pelvic inflammatory disease medicine.
6. application according to claim 5, is characterized in that, described chronic pelvic inflammatory disease is Accumulation of Dampness Heat and Blood Stasis type chronic pelvic inflammatory disease.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106692204A (en) * | 2017-03-10 | 2017-05-24 | 泰安大凡神农制药有限公司 | Probiotics composition for alleviating or improving pelvic inflammatory diseases and preparation method thereof |
| CN109420114A (en) * | 2017-08-25 | 2019-03-05 | 王停 | A kind of Chinese medicinal formulae for the conditioning of drug resistant chronic pelvic inflammatory disease |
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| CN104147209B (en) | 2016-04-13 |
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