CN106389624A - Traditional Chinese medicine unguent for treating chilblains and preparation method of traditional Chinese medicine unguent for treating chilblains - Google Patents

Traditional Chinese medicine unguent for treating chilblains and preparation method of traditional Chinese medicine unguent for treating chilblains Download PDF

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CN106389624A
CN106389624A CN201610980020.9A CN201610980020A CN106389624A CN 106389624 A CN106389624 A CN 106389624A CN 201610980020 A CN201610980020 A CN 201610980020A CN 106389624 A CN106389624 A CN 106389624A
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parts
chinese medicinal
medicinal ointment
camphora
chinese medicine
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邵雪飞
钮林霞
李冬梅
卢佳璐
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Nanyang Medical College
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Nanyang Medical College
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/758Zanthoxylum, e.g. pricklyash
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125Camphor; Nuclear substituted derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/57Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/15Pinaceae (Pine family), e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Abstract

The invention discloses a traditional Chinese medicine unguent for treating chilblains and a preparation method of the traditional Chinese medicine unguent for treating the chilblains. The traditional Chinese medicine unguent for treating the chilblains comprises, by weight, 3-5 parts of Camphora, 20-40 parts of Argy wormwood, 10-30 parts of Pericarpium Zanthoxyli, 5-15 parts of Exocarpium Benincasae, 5-15 parts of Cortex Cinnamomi, 20-30 parts of honey, 40-60 parts of egg yolk, 10-20 parts of Radix Angelicae Sinensis and 10-20 parts of turpentine. The traditional Chinese medicine unguent for treating the chilblains has the advantages that prepared from the raw materials proper in use amount and reasonable in compatibility, the traditional Chinese medicine unguent is capable of not only relieving tickle and pain caused by the chilblains but also moistening the skin; prepared from a small variety of raw materials, the traditional Chinese medicine unguent is remarkable in treatment effect by reaching the total effective rate up to 97% and the cure rate up to 93%.

Description

A kind of treat Chinese medicinal ointment of chilblain and preparation method thereof
Technical field
The invention belongs to treating skin disease Prevention Technique field, more particularly, to a kind of Chinese medicinal ointment treating chilblain and its preparation Method.
Background technology
Chilblain is to occur in tip position localized erythema diseases associated with inflammation after body is subject to cold invasion and attack, and common infringement is The edematous erythema of limitation congestive mulberry protuberance, indefinite border, severe patient can occur vesicle, formed after rupture rotten to the corn or Ulcer, has pigmentation or atrophic scar more afterwards, aggravates after itching and being heated, and symptom often occurs to leak aerial soft group sudden and violent Knit, for example ear-lobe, particularly contact the soft tissue of the joint of ice-cold external substance, such as right finger joint.Chilblain is The clinically commonly encountered diseases in winter, frequently-occurring disease, prurituss pain brings misery to patient, on the market the medicine of existing treatment chilblain Though there being certain curative effect, onset is slower, and therapeutic effect is poor, and to skin easy generation allergy.
Application number CN201510970909.4 discloses one kind and treats medical ointment for treating chilblain, and described medicine is with the material of weight proportion Make:Radix Codonopsis 8-15g, Radix Astragali 10-20g, Radix Aconiti Lateralis Preparata 3-8g, Ramulus Cinnamomi 8-15g, Radix Angelicae Sinensis 8-15g, Radix Salviae Miltiorrhizae 6-10g, Pericarpium Citri Reticulatae 5-8g, do Rhizoma Zingiberis Recens 5-8g, Radix Glycyrrhizae Preparata 5-10g, Radix Ampelopsis 10-15g, Cortex Cinnamomi 4-8g, safflower oil 4-8g, oil of ginger 4-8g, Herba Menthae 3-5g, vaseline 15- 25g, glycerol 10-15g.This structure is disadvantageous in that:Dispensing is many, high cost.
The open one kind of application number CN201410475741.5 treats chilblain external application medical ointment, including the one-tenth of following weight content Point:Flos Carthami 10-20 part, Ramulus Cinnamomi 15-20 part, Herba Schizonepetae 10-20 part, Pericarpium Zanthoxyli 20-30 part, Fructus Capsici 1-5 part, Rhizoma Alpiniae Officinarum 5-10 part, Radix Curcumae 2-3 part, vaseline 20-40 part.This invention is disadvantageous in that:For having occurred and that the chilblain symptom festered, will be containing peppery The ointment of green pepper is applied on wound, there is sense of discomfort.
Content of the invention
In view of this, the purpose of the present invention is for the deficiencies in the prior art, provide a kind of Chinese medicinal ointment treating chilblain and Its preparation method, each raw material dosage of the present invention is appropriate, and compatibility rationally, relieves the pain symptom of itching of chilblain, and has skin moistening effect Really;Raw material type is few, and treatment chilblain total effective rate reaches 97%, and cure rate reaches 93%, and therapeutic effect is notable.
For reaching above-mentioned purpose, the present invention employs the following technical solutions:
A kind of Chinese medicinal ointment treating chilblain, including the raw material of following weight portion:Camphora 3-5 part, Folium Artemisiae Argyi 20-40 part, Pericarpium Zanthoxyli 10-30 Part, Exocarpium Benincasae 5-15 part, Cortex cinnamomi japonici (Ramulus Cinnamomi) 5-15 part, Mel 20-30 part, egg yolk 40-60 part, Radix Angelicae Sinensis 10-20 part, Oleum Terebinthinae 10-20 part.
Further, Camphora be 4 parts, 30 parts of Folium Artemisiae Argyi, 20 parts of Pericarpium Zanthoxyli, 10 parts of Exocarpium Benincasae, 10 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi), 25 parts of Mel, egg 50 parts of Huang, 15 parts of Radix Angelicae Sinensis, 15 parts of Oleum Terebinthinae.
Further, Folium Artemisiae Argyi is the leaf of Qi Ai.
A kind of preparation method of the Chinese medicinal ointment treating chilblain, comprises the following steps:
(1)By Camphora, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Angelicae Sinensis go the removal of impurity, after cleaning-drying standby, take the chicken after cleaning The egg yolk of egg is standby;
(2)Weigh Camphora, Radix Angelicae Sinensis, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi), add the water of 15-20 times of medical material gross weight, soak 30- After 60min, decoct 2-4 hour, filter, obtain filtrate and filtering residue, standby;
(3)By step(2)In obtain filtrate slow fire heating, and in filtrate add Mel, be concentrated to give close with respect to water Spend the thick paste for 1.36-1.40;By step(2)In the filtering residue that obtains dry, be then ground to powder, under the conditions of 60-65 DEG C Dry, reuse small fire and fry to brown color, obtain medicated powder;
(4)By step(3)The thick paste obtaining, medicated powder mix, and are added thereto to egg yolk and Oleum Terebinthinae, and stirring 20-40min is extremely mixed Close uniformly, prepared Chinese medicinal ointment.
Further, step(1)Middle egg is cleaned after sterilized, after broken shell using disposable syringe extract egg yolk Standby.
Further, step(3)Middle drying time is 6-12h.
Further, step(3)Described in medicated powder particle diameter be 250-300 mesh.
The pharmacological action of the present invention is:
Camphora:Property heat, acrid in the mouth, GUIXIN, spleen channel;For oral administration:Having one's ideas straightened out, it is dirty to ward off, external:Dehumidifying parasite killing, temperature is scattered, antipruritic, analgesia.This product Hot dry strong, poisonous, external can dehumidify, and energy detoxicating and killing parasites, receives detumescence, antipruritic effect.This product is hot must to be dissipated, qi stagnation removing, Reducing swelling and alleviating pain;Camphora is applied to skin and has clinically has analgesia, itching-relieving action with camphorated oil.
Folium Artemisiae Argyi:Bitter in the mouth, warm in nature, enter spleen, liver and kidney channel;Have recuperating depleted YANG, rationale blood, by raw, arresting bleeding and miscarriage prevention the effects such as;Tool There is the antiabortive effect only collapsing dispelling cold and removing dampness of regulating menstruation, hemostasis, and Folium Artemisiae Argyi has antibacterial and antivirus action.
Pericarpium Zanthoxyli:Acrid in the mouth, warm in nature, returns spleen, stomach, kidney channel;There is warming middle-JIAO to promote flow of QI, dispelling cold and removing dampness, stagnation resolving, the dyspepsia that disappears, lead to three Jiao, warming the spleen stomach, mend the right kidney gate of vitality, kill ascarid, stopping leak rushes down effect.
Exocarpium Benincasae:Sweet in the mouth, cold nature, enter spleen, intestinal, warp;Having dries chases after the effect of wind, spleen reinforcing pathogenic fire purging.
Cortex cinnamomi japonici (Ramulus Cinnamomi):Acrid in the mouth, warm in nature, enter the heart, liver,spleen,kidney four warp;There is warming the spleen stomach, warm Liver and kidney, cold-dispelling pain-relieving, dissipating blood stasis for subsidence of swelling The effect of.For coldness and pain in the epigastrium, vomiting is had loose bowels, waist and knee acid is cold, the stagnant dysmenorrhea of cold hernia stomachache, arthralgia due to cold-dampnes, the stasis of blood, dysentery, hemorrhoidal hamorrhage, fall Beat and swell and ache.
Mel:Sweet in the mouth, mild-natured, return lung, spleen, large intestine channel;There is invigorating middle warmer, moisturize, pain relieving, removing toxic substances;For the empty pain of gastral cavity abdomen, lung Dry dry cough, dry constipation of intestines;External treatment skin infection is not held back, burn due to hot liquid or fire.
Egg yolk:Rich in fatsoluble vitamin, monounsaturated fatty acid, phosphorus, the trace element such as ferrum, there is the work of Glycerin With skin exquisiteness being made glossy, especially suitable dry skin and winter or the area being especially dried.
Radix Angelicae Sinensis:Sweet in the mouth, warm in nature, Return liver, the heart, spleen channel;Have enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation the effect of.Can For all cards of main blood deficiency, menoxenia, amenorrhea, dysmenorrhea, lump in the abdomen knot be poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, dryness of the intestine just Weight, ulcer sores, injury from falling down after hardly possible, bloody dysentery.
Oleum Terebinthinae:There is enhancement local blood circulation, alleviate swelling and slight analgesic effect;For mitigating myalgia, pass Arthralgia, neuralgia and sprain.
The invention has the beneficial effects as follows:
1. Chinese medicine preparation of the present invention treats chilblain, according to its cause of disease and clinical onset feature, with damp eliminating, repellent antipruritic for treatment side Method carries out prescription medicine, and with Camphora, Folium Artemisiae Argyi, three kinds of Chinese medicines of Pericarpium Zanthoxyli as monarch drug, Camphora is applied to skin and has dehumidifying, antipruritic, analgesia Effect, Folium Artemisiae Argyi and Pericarpium Zanthoxyli have rationale blood, by raw effect;In addition, Chinese medicine preparation of the present invention uses Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi) auxiliary Help, the phenomenon improve patients symptomatic's skin turgor further, being chapped from the cold, all medicines share, altogether for ministerial drug;Additionally, Radix Angelicae Sinensis have thin blood Promoting blood circulation effect, the drug effect effectively improving monarch drug and the effective drug duration strengthening monarch drug, and Radix Angelicae Sinensis herb has the characteristics that fragrance The penetrating odor of Camphora is effectively nursed one's health, prevents from coating procedure, causing abnormal smells from the patient sense of discomfort, be adjuvant drug;Oleum Terebinthinae conduct Make medicine promote the blood circulation at symptom, and Oleum Terebinthinae has volatility and is conducive to drug storage to go directly focus, especially for pass Chilblain at section, Oleum Terebinthinae also helps the effect improving rheumatic arthritis, antibacterial.
In addition, it is adjuvant that the present invention uses Mel, egg yolk, Mel and egg yolk contain the amino being absorbed by the body in a large number Acid, enzyme, hormone, vitamin and sugar, have functions that gentle skin and nourishes rough skin, and after preventing relieving itching and eliminating swelling, superficial skin occurs Fold, the phenomenon of peeling, effectively improve the soothing effect of the present invention.
To sum up, disclosed by the invention treatment chilblain Chinese medicinal ointment, between plurality of raw materials mutually support, mutually collaborative, make medicine Imitate at through disease and realize internal and external application, shorten treatment cycle, improve therapeutic effect.
2. the preparation method of the present invention is simple, using boiling each taste raw material of Chinese medicine by slow fire so that effective in raw material of Chinese medicine Composition is at utmost leached, and obtains thick paste;Then using middle oven drying at low temperature, stir-fry medicinal residues, grinds to form medicated powder, finally will be thick Cream and medicated powder are used in mixed way, the comprehensive effective ingredient remaining raw material of Chinese medicine of the Chinese medicine patch of preparation so that Chinese medicine patch effective Composition can farthest be absorbed by the patient.
In addition, this method using traditional decoction and grind compounding form, prepared Chinese medicinal ointment Small side effects, to human body skin Skin or wound do not have zest, short treating period, and cure rate is high, and low cost has wide market prospect.
Specific embodiment
With reference to embodiment, the invention will be further described.
Embodiment one
A kind of Chinese medicinal ointment treating chilblain, including the raw material of following weight portion:3 parts of Camphora, 20 parts of Folium Artemisiae Argyi, 10 parts of Pericarpium Zanthoxyli, Fructus Benincasae 5 parts of skin, 5 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi), 20 parts of Mel, 40 parts of egg yolk, 10 parts of Radix Angelicae Sinensis, 10 parts of Oleum Terebinthinae.
Its preparation method, comprises the following steps:
(1)By Camphora, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Angelicae Sinensis go the removal of impurity, after cleaning-drying standby, take egg to surface After being carried out, extract its egg yolk using disposable syringe standby;
(2)Weigh Camphora, Radix Angelicae Sinensis, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi) by formula and mix, add 15 times of medical material gross weights Water, after soaking 30min, decocts 2 hours, filters, obtain filtrate and filtering residue, standby;
(3)By step(2)In obtain filtrate slow fire heating, and in filtrate add Mel, be concentrated to give close with respect to water Spend the thick paste for 1.36;By step(2)In the filtering residue that obtains dry, be then ground to the powder of 250 mesh, dry under the conditions of 60 DEG C Dry 6h, and fried to brown color using small fire, obtain medicated powder;
(4)By step(3)The thick paste obtaining, medicated powder mix, and are added thereto to egg yolk and Oleum Terebinthinae using syringe, stirring 20min to mix homogeneously, prepared Chinese medicinal ointment.
Embodiment two
A kind of Chinese medicinal ointment treating chilblain, including the raw material of following weight portion:3.5 parts of Camphora, 25 parts of Folium Artemisiae Argyi, 15 parts of Pericarpium Zanthoxyli, winter 6 parts of melon skin, 6 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi), 22 parts of Mel, 45 parts of egg yolk, 12 parts of Radix Angelicae Sinensis, 12 parts of Oleum Terebinthinae.
Its preparation method, comprises the following steps:
(1)By Camphora, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Angelicae Sinensis go the removal of impurity, after cleaning-drying standby, take egg to surface After being carried out, extract its egg yolk using disposable syringe standby;
(2)Weigh Camphora, Radix Angelicae Sinensis, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi) by formula and mix, add 16 times of medical material gross weights Water, after soaking 35min, decocts 2 hours, filters, obtain filtrate and filtering residue, standby;
(3)By step(2)In obtain filtrate slow fire heating, and in filtrate add Mel, be concentrated to give close with respect to water Spend the thick paste for 1.37;By step(2)In the filtering residue that obtains dry, be then ground to the powder of 260 mesh, dry under the conditions of 60 DEG C Dry 7h, and fried to brown color using small fire, obtain medicated powder;
(4)By step(3)The thick paste obtaining, medicated powder mix, and are added thereto to egg yolk and Oleum Terebinthinae using syringe, stirring 25min to mix homogeneously, prepared Chinese medicinal ointment.
Embodiment three
A kind of Chinese medicinal ointment treating chilblain, including the raw material of following weight portion:4 parts of Camphora, 25 parts of the leaf of Qi Ai, 15 parts of Pericarpium Zanthoxyli, 10 parts of Exocarpium Benincasae, 8 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi), 25 parts of Mel, 50 parts of egg yolk, 14 parts of Radix Angelicae Sinensis, 13 parts of Oleum Terebinthinae.
Its preparation method, comprises the following steps:
(1)By Camphora, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Angelicae Sinensis go the removal of impurity, after cleaning-drying standby, take egg to surface After being carried out, extract its egg yolk using disposable syringe standby;
(2)Weigh Camphora, Radix Angelicae Sinensis, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi) by formula and mix, add 17 times of medical material gross weights Water, after soaking 45min, decocts 3 hours, filters, obtain filtrate and filtering residue, standby;
(3)By step(2)In obtain filtrate slow fire heating, and in filtrate add Mel, be concentrated to give close with respect to water Spend the thick paste for 1.38;By step(2)In the filtering residue that obtains dry, be then ground to the powder of 270 mesh, dry under the conditions of 62 DEG C Dry 8h, and fried to brown color using small fire, obtain medicated powder;
(4)By step(3)The thick paste obtaining, medicated powder mix, and are added thereto to egg yolk and Oleum Terebinthinae using syringe, stirring 28min to mix homogeneously, prepared Chinese medicinal ointment.
Example IV
A kind of Chinese medicinal ointment treating chilblain, including the raw material of following weight portion:4 parts of Camphora, 30 parts of Folium Artemisiae Argyi, 20 parts of Pericarpium Zanthoxyli, Fructus Benincasae 10 parts of skin, 10 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi), 25 parts of Mel, 50 parts of egg yolk, 15 parts of Radix Angelicae Sinensis, 15 parts of Oleum Terebinthinae.
Its preparation method, comprises the following steps:
(1)By Camphora, the leaf of Qi Ai, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Angelicae Sinensis go the removal of impurity, after cleaning-drying standby, first by egg Clean and use ozone to surface sterilization, extract egg yolk using disposable syringe after broken shell standby;
(2)Weigh Camphora, Radix Angelicae Sinensis, the leaf of Qi Ai, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi) by formula and mix, add 17.5 times of medical material gross weights The water of amount, after soaking 45min, decocts 3 hours, filters, obtain filtrate and filtering residue, standby;
(3)By step(2)In obtain filtrate slow fire heating, and in filtrate add Mel, be concentrated to give close with respect to water Spend the thick paste for 1.38;By step(2)In the filtering residue that obtains dry, be then ground to the powder of 300 mesh, dry under the conditions of 65 DEG C Dry 9h, and fried to brown color using small fire, obtain medicated powder;
(4)By step(3)The thick paste obtaining, medicated powder mix, and are added thereto to egg yolk and Oleum Terebinthinae using syringe, stirring 30min to mix homogeneously, prepared Chinese medicinal ointment.
In the present embodiment, preparation method step(1)Using ozone, sterilizing is carried out to egg surface, prevent on Ovum crusta Gallus domesticuss Escherichia coli, staphylococcus aureuses, the pathogenic bacterium such as Candida albicans affect the property of medicine of Chinese medicinal ointment, increase the absorption of its property of medicine Rate.
Embodiment five
A kind of Chinese medicinal ointment treating chilblain, including the raw material of following weight portion:4 parts of Camphora, 30 parts of the leaf of Qi Ai, 20 parts of Pericarpium Zanthoxyli, 10 parts of Exocarpium Benincasae, 10 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi), 5 parts of Aloe, 25 parts of Mel, 50 parts of egg yolk, 15 parts of Radix Angelicae Sinensis, 15 parts of Oleum Terebinthinae.
Its preparation method, comprises the following steps:
(1)By Camphora, the leaf of Qi Ai, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Angelicae Sinensis go the removal of impurity, after cleaning-drying standby, first by egg Clean and use ozone to surface sterilization, extract egg yolk using disposable syringe after broken shell standby;
(2)Weigh Camphora, Radix Angelicae Sinensis, the leaf of Qi Ai, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi) by formula and mix, add 17.5 times of medical material gross weights The water of amount, after soaking 50min, decocts 3 hours, filters, obtain filtrate and filtering residue, standby;
(3)By step(2)In obtain filtrate slow fire heating, and in filtrate add Mel, be concentrated to give close with respect to water Spend the thick paste for 1.38;By step(2)In the filtering residue that obtains dry, then pulverize and grind to form the powder of 300 mesh, in 65 DEG C of bars 9h under part, and fried to brown color using small fire, obtain medicated powder;
(4)By step(3)The thick paste that obtains, medicated powder mixing, and be added thereto to egg yolk and Oleum Terebinthinae using syringe, afterwards plus Enter Aloe and be stirred 30min to mix homogeneously, prepared Chinese medicinal ointment.
In the present embodiment, preparation method step(3)First the filtering residue after drying is pulverized and be ground, be conducive to carrying The high efficiency ground, and increase Aloe in adjuvant, using Aloe, there is special gel, make prepared ointment shape more Good, and Aloe can nourish to the skin at symptom further, improves the soothing effect of the present invention.
Embodiment six
A kind of Chinese medicinal ointment treating chilblain, including the raw material of following weight portion:4 parts of Camphora, 35 parts of Folium Artemisiae Argyi, 25 parts of Pericarpium Zanthoxyli, Fructus Benincasae 12 parts of skin, 12 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi), 25 parts of Mel, 50 parts of egg yolk, 16 parts of Radix Angelicae Sinensis, 15 parts of Oleum Terebinthinae.
Its preparation method, comprises the following steps:
(1)By Camphora, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Angelicae Sinensis go the removal of impurity, after cleaning-drying standby, take egg to surface After being carried out, extract its egg yolk using disposable syringe standby;
(2)Weigh Camphora, Radix Angelicae Sinensis, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi) by formula and mix, add 18 times of medical material gross weights Water, after soaking 50min, decocts 3 hours, filters, obtain filtrate and filtering residue, standby;
(3)By step(2)In obtain filtrate slow fire heating, and in filtrate add Mel, be concentrated to give close with respect to water Spend the thick paste for 1.38;By step(2)In the filtering residue that obtains dry, be then ground to the powder of 300 mesh, dry under the conditions of 60 DEG C Dry 10h, and fried to brown color using small fire, obtain medicated powder;
(4)By step(3)The thick paste obtaining, medicated powder mix, and are added thereto to egg yolk and Oleum Terebinthinae using syringe, stirring 30min to mix homogeneously, prepared Chinese medicinal ointment.
Embodiment seven
A kind of Chinese medicinal ointment treating chilblain, including the raw material of following weight portion:4.5 parts of Camphora, 38 parts of Folium Artemisiae Argyi, 28 parts of Pericarpium Zanthoxyli, winter 14 parts of melon skin, 13 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi), 28 parts of Mel, 55 parts of egg yolk, 18 parts of Radix Angelicae Sinensis, 17 parts of Oleum Terebinthinae.
Its preparation method, comprises the following steps:
(1)By Camphora, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Angelicae Sinensis go the removal of impurity, after cleaning-drying standby, take egg to surface After being carried out, extract its egg yolk using disposable syringe standby;
(2)Weigh Camphora, Radix Angelicae Sinensis, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi) by formula and mix, add 19 times of medical material gross weights Water, after soaking 55min, decocts 3.5 hours, filters, obtain filtrate and filtering residue, standby;
(3)By step(2)In obtain filtrate slow fire heating, and in filtrate add Mel, be concentrated to give close with respect to water Spend the thick paste for 1.39;By step(2)In the filtering residue that obtains dry, be then ground to the powder of 300 mesh, dry under the conditions of 63 DEG C Dry 11h, and fried to brown color using small fire, obtain medicated powder;
(4)By step(3)The thick paste obtaining, medicated powder mix, and are added thereto to egg yolk and Oleum Terebinthinae using syringe, stirring 35min to mix homogeneously, prepared Chinese medicinal ointment.
Embodiment eight
A kind of Chinese medicinal ointment treating chilblain, including the raw material of following weight portion:5 parts of Camphora, 40 parts of Folium Artemisiae Argyi, 30 parts of Pericarpium Zanthoxyli, Fructus Benincasae 15 parts of skin, 15 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi), 30 parts of Mel, 60 parts of egg yolk, 20 parts of Radix Angelicae Sinensis, 20 parts of Oleum Terebinthinae.
Its preparation method, comprises the following steps:
(1)By Camphora, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Angelicae Sinensis go the removal of impurity, after cleaning-drying standby, take egg to surface After being carried out, extract its egg yolk using disposable syringe standby;
(2)Weigh Camphora, Radix Angelicae Sinensis, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi) by formula and mix, add 20 times of medical material gross weights Water, after soaking 60min, decocts 4 hours, filters, obtain filtrate and filtering residue, standby;
(3)By step(2)In obtain filtrate slow fire heating, and in filtrate add Mel, be concentrated to give close with respect to water Spend the thick paste for 1.40;By step(2)In the filtering residue that obtains dry, be then ground to the powder of 300 mesh, dry under the conditions of 65 DEG C Dry 12h, and fried to brown color using small fire, obtain medicated powder;
(4)By step(3)The thick paste obtaining, medicated powder mix, and are added thereto to egg yolk and Oleum Terebinthinae using syringe, stirring 40min to mix homogeneously, prepared Chinese medicinal ointment.
Clinical trial
First, test case
Over the past two years, accept face chilblain 249 altogether for medical treatment, wherein male patient populations are 156, age gradient 3-72 year, female patient's number Measure as 93, age gradient be 4-65 year.
2nd, diagnostic criteria
Symptom includes:It is apt to occur in extremity tip and exposure portion, be common in the patient brothers back side, be distributed symmetrically, often have special rainbow Film sample damages, and is sometimes found in face, buttockss, oral cavity etc..Show as that aubergine lump, Pi Wen are low, numb, heat is then to the cold Itch, severe patient easily forms vesicle ulcer, after ulcer healing, leave atrophic cicatrix.
3rd, Therapeutic Method
Dry after skin is cleaned, the Chinese medicinal ointment of the present invention is coated in symptom position, each coating sooner or later once, five days is a treatment Journey, 1 course for the treatment of of the lighter patient medication of clinical symptoms, 2 courses for the treatment of of heavier patient medication;Pungent, greasy, cold and cool food is prohibited during treatment Thing, it is to avoid child's mouth is eaten.
4th, the standard of curative effect evaluation
Cure:Each symptom all disappears, and chilblain skin is antipruritic, detumescence, the colour of skin are normal, no atrophy cicatrix.
Effective:Non-evident sympton and sign, relieving itching and eliminating swelling, but at symptom it is still redness.
Invalid:Subjective symptom and objective sign no improve.
5th, result
249 chilblain are treated, total effective rate reaches 97%, cure rate reaches 93%, and therapeutic effect is notable.
Model case
Case 1:Lee, man, 3 years old, people from Henan Fangcheng, the winter in 2015, suffers from chilblain about one week, fails to understand in local repeatedly therapeutic effect Aobvious, to when going to a doctor in here, redness in patient's right hand middle finger joint, and with sufferings symptom.Using embodiments of the invention 4 External used medicine coat three days after, clinical symptom disappearance.The Effect of follow-up visit by telephone after two months that is discontinued did not recurred.
2. Dong, man, 16 years old, Tongbai in Henan Province people, the year before suffer from right hand hand side chilblain, through treatment after effect not Good, the winter in 2015 reappears chilblain in original position, and to when going to a doctor in here, symptom is red and swollen, blister, and with pain symptom. Coat after a course for the treatment of using the external used medicine of embodiments of the invention 4, clinical symptom disappearance.Be discontinued Effect of follow-up visit by telephone after two months Do not recurred, skin scar phenomenon did not occurred yet.
3. Lee so-and-so, man, 71 years old, Tongbai in Henan Province people, the winter in 2015, suffer from chilblain about ten days, to here go to a doctor when, patient Redness, is chapped from the cold in ears ear-lobe.External used medicine using embodiments of the invention 4 coats after a course for the treatment of, and clinical symptoms disappear Lose.The Effect of follow-up visit by telephone after two months that is discontinued did not recurred.
4. Ma, female, 23 years old, Nanyang, henan people, the winter in 2014 I gone to a doctor, when medical, left symptom be face flushing Swollen, stiff, local skin blacks.External used medicine using embodiments of the invention 5 coats after two courses for the treatment of, and clinical symptoms disappear Lose.The Effect of follow-up visit by telephone after two months that is discontinued did not recurred.
5. Chen, female, 46 years old, Henan table mountain people from Lushan County, the spring in 2016 I gone to a doctor, when medical, left symptom For finger many places, sufferings, ulcer occur.Coat after two courses for the treatment of using the external used medicine of embodiments of the invention 5, clinical symptoms Disappear, skin recovers as before.After being discontinued one month, Effect of follow-up visit by telephone did not recur.
Finally illustrate, only in order to technical scheme to be described and unrestricted, this area is common for above example Other modifications or equivalent that technical staff is made to technical scheme, without departing from technical solution of the present invention Spirit and scope, all should cover in the middle of scope of the presently claimed invention.

Claims (7)

1. a kind of Chinese medicinal ointment treating chilblain is it is characterised in that include the raw material of following weight portion:Camphora 3-5 part, Folium Artemisiae Argyi 20- 40 parts, Pericarpium Zanthoxyli 10-30 part, Exocarpium Benincasae 5-15 part, Cortex cinnamomi japonici (Ramulus Cinnamomi) 5-15 part, Mel 20-30 part, egg yolk 40-60 part, Radix Angelicae Sinensis 10-20 part, Oleum Terebinthinae 10-20 part.
2. a kind of Chinese medicinal ointment treating chilblain according to claim 1 it is characterised in that:Camphora be 4 parts, 30 parts of Folium Artemisiae Argyi, 20 parts of Pericarpium Zanthoxyli, 10 parts of Exocarpium Benincasae, 10 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi), 25 parts of Mel, 50 parts of egg yolk, 15 parts of Radix Angelicae Sinensis, 15 parts of Oleum Terebinthinae.
3. a kind of Chinese medicinal ointment treating chilblain according to claim 1 is it is characterised in that Folium Artemisiae Argyi is the leaf of Qi Ai.
4. a kind of preparation method of the Chinese medicinal ointment for the treatment of chilblain described in any one according to claim 1-3 is it is characterised in that wrap Include following steps:
(1)By Camphora, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Angelicae Sinensis go the removal of impurity, after cleaning-drying standby, take the chicken after cleaning The egg yolk of egg is standby;
(2)Weigh Camphora, Radix Angelicae Sinensis, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi), add the water of 15-20 times of medical material gross weight, soak 30- After 60min, decoct 2-4 hour, filter, obtain filtrate and filtering residue, standby;
(3)By step(2)In obtain filtrate slow fire heating, and in filtrate add Mel, be concentrated to give close with respect to water Spend the thick paste for 1.36-1.40;By step(2)In the filtering residue that obtains dry, be then ground to powder, under the conditions of 60-65 DEG C Dry, reuse small fire and fry to brown color, obtain medicated powder;
(4)By step(3)The thick paste obtaining, medicated powder mix, and are added thereto to egg yolk and Oleum Terebinthinae, and stirring 20-40min is extremely mixed Close uniformly, prepared Chinese medicinal ointment.
5. the preparation method of the Chinese medicinal ointment for the treatment of chilblain according to claim 4 is it is characterised in that step(1)Middle by chicken Ovum Gallus domesticus album carries out disinfection after washing, and extracts egg yolk using disposable syringe standby after broken shell.
6. the preparation method of the Chinese medicinal ointment for the treatment of chilblain according to claim 4 is it is characterised in that step(3)Middle drying Time is 6-12h.
7. the preparation method of the Chinese medicinal ointment for the treatment of chilblain according to claim 4 is it is characterised in that step(3)Described in The particle diameter of medicated powder is 250-300 mesh.
CN201610980020.9A 2016-11-08 2016-11-08 Traditional Chinese medicine unguent for treating chilblains and preparation method of traditional Chinese medicine unguent for treating chilblains Pending CN106389624A (en)

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