CN102258602A - Chinese medicinal composition for treating rheumatism and rheumatoid and preparation method thereof - Google Patents
Chinese medicinal composition for treating rheumatism and rheumatoid and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a Chinese medicinal composition for treating rheumatism and rheumatoid. The composition consists of the following raw materials in percentage by weight: 25-35 percent of divaricate saposhnikovia root, 11-25 percent of schizonepeta, 11-25 percent of notopterygium root, 5-15 percent of radix angelicae pubescentis, 5-15 percent of safflower, 5-15 percent of xanthium strumarium and 2-6 percent of saussurea acrophila, wherein the total mass percent of the components is 100 percent. The invention also discloses a preparation method of the Chinese medicinal composition. The Chinese medicinal composition is prepared by weighing each raw material, crushing and fully mixing. The Chinese medicinal composition for treating rheumatism and rheumatoid has the advantages of good curative effect, quick response and no toxic or side effect.
Description
Technical field
The invention belongs to technical field of Chinese medicines, relate to a kind of treatment rheumatism, rheumatoid Chinese medicine composition, the invention still further relates to the preparation method of this Chinese medicine composition.
Background technology
Rheumatism, rheumatoid are a kind of common inflammation, and rheumatism is one group of disease that general reference influences bone, joint and surrounding soft tissue thereof such as tendon, synovial membrane, fascia etc., is cardinal symptom with pain such as joint, muscle, soft tissue, nerves.Often show as slight heating or middle heat, the pathological changes part presents symptoms such as redness, scorching hot, severe pain, distending pain.Rheumatic arthritis is that wind, cold, damp are invaded human body and caused, the multiple abscess meridians, QI-blood circulation lose smooth due to.Rheumatoid disease is not because of also very clear and definite, the little arthralgia of normal appearance, increase, can invade big joint and heart, brain, lung, blood vessel etc. when serious, treatment rheumatism, rheumatoid mainly adopt the Western medicine of plaster and anti-inflammatory class at present, but only cure the symptoms, not the disease, easily repeatedly, and Western medicine has side effect, and long-term prescription can bring the degeneration of physical function.
Summary of the invention
The purpose of this invention is to provide a kind of treatment rheumatism, rheumatoid Chinese medicine composition, good effect, instant effect has no side effect.
Another object of the present invention provides the preparation method of above-mentioned Chinese medicine composition.
The technical solution adopted in the present invention is, a kind of treatment rheumatism, rheumatoid Chinese medicine composition are made up of following raw material according to mass percent:
Radix Saposhnikoviae 25% ~ 35%, Herba Schizonepetae 11% ~ 25%, Rhizoma Et Radix Notopterygii 11% ~ 25%, Radix Angelicae Pubescentis 5% ~ 15%, Flos Carthami 5% ~ 15%, Herba Xanthii 5% ~ 15%, Pyrola rotundifolia ssp.chinensis 2% ~ 6%, the mass percent summation of above component is 100%.
Another technical scheme of the present invention is, the preparation method of treatment rheumatism, rheumatoid Chinese medicine composition is specifically carried out according to following steps:
Step 1
According to mass percent, take by weighing 25% ~ 35% Radix Saposhnikoviae, 11% ~ 25% Herba Schizonepetae, 11% ~ 25% Rhizoma Et Radix Notopterygii, 5% ~ 15% Radix Angelicae Pubescentis, 5% ~ 15% Flos Carthami, 5% ~ 15% Herba Xanthii, 2% ~ 6% Pyrola rotundifolia ssp.chinensis respectively, the mass percent summation of above raw material is 100%;
Step 2
Each raw material pulverizing that step 1 is taken by weighing, fully promptly make after mixing.
Treatment rheumatism of the present invention, rheumatoid Chinese medicine composition can be made rheumatoid fumigant, two kinds of preparations of rheumatoid reparation spray, good effect, and instant effect has no side effect.Two kinds of preparations can dispose separately, use separately.The rheumatoid fumigant is mainly used in rheumatoid, rheumatism, gout etc. and uses in gassing machine; Solve rheumatism, rheumatoid, gout etc. and cause that arthroncus crosses the reparation and the rehabilitative action of arthralgia, and pain-relieving rheumatism-dispelling heat rapidly, control activeness rheumatoid and rheumatism reach the part or hydrosarca alleviates until disappearance.From immune disorder of external adjusting human body and deficiency, shorten and treat rheumatism, rheumatoid time and the course of treatment, compare with chemicals than traditional oral drugs, this composition of medicine need not be oral, do not injure human body, thereby the blood circulation and the immune system of regulating human body reach therapeutic purposes.Rheumatoid is repaired spray and is mainly used in rheumatoid, rheumatism, gout, scapulohumeral periarthritis, intervertebral disk hernia or bulging, cervical vertebra pain, sprain, carry out at magnet therapeutic apparatus or infrared therapy apparatus that ion is got involved and soak penetrates the diseased region topical therapeutic, through thermion, photoion or magnetic wave enter blood circulation with effective ingredient Transdermal absorption and arrive each tissue, higher in diseased region concentration, the deleterious metabolite of pathological tissues is decomposed, kills the rheumatoid factor in the blood; the osteoclast of pathological changes joint part; abnormal proliferation cell; the allergy cell; Decompose ruined histiocyte and immune complex, get rid of externally through blood circulation, recover the microcirculqtory system of diseased region, set up normal blood circulation passage, allow the automatic and passive reparation pathological tissues of human body, thereby reach therapeutic purposes.Can solve infrared ray and magnet therapeutic apparatus does not have the defective of soak and hot compress, promotes local lesion's rehabilitation to shorten the course of treatment.According to clinical trial, the rheumatoid fumigant can be controlled rheumatic fever that the activeness rheumatoid causes and rheumatalgia, migratory rheumatism pain in 3-4 days, light disease rheumatic arthritis can be cured in 7 days substantially, recovery from illness in 25 days, rheumatoid fumigant and rheumatoid reparation spray use simultaneously can control violent arthralgia in 10 days, rheumatoid returned to one's perfect health and reaches 97% in 3 months to 6 months, and common knee joint rheumatic arthritis returned to one's perfect health 78% in 25 days.
The specific embodiment
The present invention is described in detail below by the specific embodiment.
Treatment rheumatism of the present invention, rheumatoid Chinese medicine composition, form by following raw material according to mass percent:
Radix Saposhnikoviae 25% ~ 35%, Herba Schizonepetae 11% ~ 25%, Rhizoma Et Radix Notopterygii 11% ~ 25%, Radix Angelicae Pubescentis 5% ~ 15%, Flos Carthami 5% ~ 15%, Herba Xanthii 5% ~ 15%, Pyrola rotundifolia ssp.chinensis 2% ~ 6%, the mass percent summation of above component is 100%.
Among the present invention, the Radix Saposhnikoviae acrid-sweet flavor is warm in nature nontoxic, and suffering is walked the agent of lung so lead to the knot for the treatment of all pathogenic wind, the trouble of pain person's wind.
Herba Schizonepetae acrid in the mouth bitterness tepor, nontoxicly go into the promoting the circulation of blood of lung liver and treat all wind of wind diaphoresis peeling hair.The Herba Schizonepetae in vitro tests has weak anticancer effect.The Herba Schizonepetae decoct has the effect of obvious inhibition mice auricle swelling, and the inflammation that Dichlorodiphenyl Acetate causes also has the obvious anti-inflammatory and anti effect.
Rhizoma Et Radix Notopterygii sweet in the mouth slightly warm in nature is gone into lung kidney two through curing mainly new and old all rheumatism numbness, goes into the few cloudy kidney of lunar lung to manage floating wind.Rhizoma Et Radix Notopterygii volatile oil has antiinflammatory and anti-allergic effects.Behind gastric infusion, xylol dropsy of ear, carrageenin and dextran foot swelling have inhibitory action.To 2, the caused delayed hypersensitivity of 4-dinitrochlorobenzene has certain inhibitory action, and can make the interior Vitamin C content of adrenal gland that reduction trend is arranged. and its antiinflammatory action may be relevant with hypophysis-interrenal system.
Radix Angelicae Pubescentis bitter but sweet flavor slightly warm in nature is nontoxic goes into the small intestinal urinary bladder channel and spills into the table ailment said due to cold or exposure, and sharp Zhousheng arthralgia is removed the disease of new and old rheumatism and gone into sun small intestinal, bladder meridian with the mutual the exterior and the interior of reason urticaria.Book on Chinese herbal medicine converges to be sayed: Radix Angelicae Pubescentis, and the benefaction blood system, the medicine of the wet cold expelling of row that dispels the wind is also.The card of all sick wind can not pitching as head term, and the waist knee joint can not bend and stretch, or arthralgia pain is difficult to walk, numbness need not, all wind with cold due to, summer-heat and wet institute wound are also; Must be with the toil of Radix Angelicae Pubescentis and temperature, the activity QI and blood, the cold expelling heresy of dispelling, the beriberi so " book on Chinese herbal medicine " speech can loose is changed renal mass, treatment hernia abdominal mass, subduing inflammation is controlled harmful wind hundred and is saved and attack bitterly, and the strongly fragrant headache of YIN-cold less is intended to this surely.
Flos Carthami acrid in the mouth nontoxic conscience two warps of going into warm in nature are treated the swelling of traumatic injury sore.Carthamus yellow has calmness, analgesia and anti-frightened effect.Mice hot plate method and acetic acid twisting experimental results show that: Carthamus yellow has analgesic activity, and can strengthen the central inhibitory action of barbital and chloral hydrate, reduces the response rate and the mortality rate of nikethamide convulsions.Extract can suppress the caused foot swelling of carrageenin, points out it that antiinflammatory action is arranged.The total flavin of Flos Carthami also has immunosuppressive action, can reduce the leukocytic phagocytic function of serum lysozyme content, peritoneal macrophage and whole blood.
The Herba Xanthii grass acrid-sweet flavor slightly poisonous anemofrigid-damp arthralgia that cures mainly warm in nature." herbal classic ": Herba Xanthii grass " the spasm of the limbs pain is disliked the dead mark of meat for the cold pain of main air head, rheumatism general arthralgia " is used for rheumatic arthralgia.This product expelling wind and removing dampness, removing obstruction in the collateral to relieve pain is used the dispelling the wind and dampness pathogens arthromyodynia, and spasm of the limbs can singly be used.
The Pyrola rotundifolia ssp.chinensis sweet in the mouth is warm in nature, and is slightly poisonous, removing blood stasis, externally used detumescence pain relieving, blood circulation promoting and blood stasis dispelling, the nameless gall that disappears, rheumatalgia.
Radix Saposhnikoviae is that monarch drug goes first of all wind in the middle of the present invention, and Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis are that the auxilliary Radix Saposhnikoviae of minister removes anemofrigid-damp arthralgia, and Flos Carthami, Herba Xanthii grass, Pyrola rotundifolia ssp.chinensis are for helping the monarch and his subjects' power reducing swelling and alleviating pain, and Herba Schizonepetae leads all medicines to disperse whole body to treat the anemofrigid-damp arthralgia reducing swelling and alleviating pain for making.
The preparation method of treatment rheumatism of the present invention, rheumatoid Chinese medicine composition, specifically implement according to following steps:
Step 1
According to mass percent, take by weighing 25% ~ 35% Radix Saposhnikoviae, 11% ~ 25% Herba Schizonepetae, 11% ~ 25% Rhizoma Et Radix Notopterygii, 5% ~ 15% Radix Angelicae Pubescentis, 5% ~ 15% Flos Carthami, 5% ~ 15% Herba Xanthii, 2% ~ 6% Pyrola rotundifolia ssp.chinensis respectively, the mass percent summation of above component is 100%;
Step 2
Each raw material that step 1 takes by weighing is pulverized, after abundant the mixing, promptly made with pulverizer.
Can make fumigant with ventilative non-toxic material package by treatment rheumatism, rheumatoid Chinese medicine composition that said method makes.Using method is: fumigant is put into gassing machine fumigate, temperature is controlled between 39-60 degree centigrade, be advisable with the human body tolerance, and between time 30-40 minute, can not be above 40 minutes.
The treatment rheumatism, the rheumatoid Chinese medicine composition that make by said method can also add water, the mixed that adds 2000ml water according to per 53 gram Chinese medicine compositions, heated 20 minutes to 95-100 degree centigrade, extract effective liquid with the high pressure extract method and make rheumatism, rheumatoid repair liquid spray, be sprayed at lesion with nebulizer during for infrared ray and magnet therapeutic apparatus treatment.
Treatment rheumatism of the present invention, rheumatoid Chinese medicine composition, the allergic constitution forbidding, serious symptom heart patient avoids usefulness.
The present invention treats fumigant that rheumatism, rheumatoid Chinese medicine composition makes and rheumatoid repair liquid spray and can arrange in pairs or groups jointly and use treatment rheumatism, rheumatoid.
Pharmacodynamic experiment:
Rheumatism, rheumatoid Chinese medicine composition analgesic activity:
1, to the influence of the mice threshold of pain:
Adopt hot plate method to measure the threshold of pain, its condition is that hot plate temperature is 55 ± 0.5 ℃.Get body weight 18g-20g female mice, select 20 of the mices that its response latency is no more than 30 hours after the response latency, divide equally two groups, smear the affected part with water decoction for one group; Another group is for matched group, to medicine.First group is applied in the affected part with rheumatism, rheumatoid Chinese medicine composition water decoction (Chinese medicine composition 40g/kg of the present invention and 40ml water mix), measure the administration front and back mice response latency, the response latency of rheumatism, rheumatoid Chinese medicine composition group mice has proved that taking medicine back 60 hours and all obviously prolongations in 90 hours rheumatism, rheumatoid Chinese medicine composition have analgesic effect preferably as a result.
2, electricity irritation Mus tail method:
Electricity irritation Mus tail method is measured analgesic effect, and its condition is that the unidirectional current time spent 1-2 of 180v wounds mouse tail second, surveys the pain reaction number of times of mice, gets 10 of the mices of 16 grams-20 gram body weight, is divided into two groups, 5 every group, is divided into matched group and reference group.White mice and spray are that every kg body weight white mice is treated rheumatism, rheumatoid Chinese medicine composition with 20g according to weight ratio, and every kg body weight is treated rheumatism, rheumatoid Chinese medicine composition with 42g, Chinese medicine composition is made rheumatism, rheumatoid repair liquid spray according to the mixed that per 53 gram Chinese medicine compositions add 2000ml water again, being sprayed on the white mice affected part observes, 10 minutes analgesia rates are respectively 71% and 86% after the administration, analgesia rate after 60 minutes then distinguishes 89% and 97%, and certain analgesic activity is all arranged as can be seen.
Anxious poison experiment:
Giving 20 healthy people with doubly rheumatism of 2-3, fumigant that rheumatoid Chinese medicine composition makes fumigates, do not find toxic reaction, continue and be sprayed on joint part to rheumatism, rheumatoid repair liquid spray 200ml, simultaneously with infrared ray and magnet therapeutic apparatus irradiation, observe no toxic reaction in 1-48 hour, local nothing is red and swollen, does not have irritated reaction.
Embodiment 1
According to mass percent, take by weighing 33% Radix Saposhnikoviae, 25% Herba Schizonepetae, 25% Rhizoma Et Radix Notopterygii, 5% Radix Angelicae Pubescentis, 5% Flos Carthami, 5% Herba Xanthii, 2% Pyrola rotundifolia ssp.chinensis respectively, after each raw material that takes by weighing is pulverized, fully mixed with pulverizer, promptly make.
Embodiment 2
According to mass percent, take by weighing 25% Radix Saposhnikoviae, 13% Herba Schizonepetae, 11% Rhizoma Et Radix Notopterygii, 15% Radix Angelicae Pubescentis, 15% Flos Carthami, 15% Herba Xanthii, 6% Pyrola rotundifolia ssp.chinensis respectively, after each raw material that takes by weighing is pulverized, fully mixed with pulverizer, promptly make.
Embodiment 3
According to mass percent, take by weighing 35% Radix Saposhnikoviae, 11% Herba Schizonepetae, 20% Rhizoma Et Radix Notopterygii, 10% Radix Angelicae Pubescentis, 10% Flos Carthami, 10% Herba Xanthii, 4% Pyrola rotundifolia ssp.chinensis respectively, after each raw material that takes by weighing is pulverized, fully mixed with pulverizer, promptly make.
Claims (2)
1. treat rheumatism, rheumatoid Chinese medicine composition for one kind,, form by following raw material according to mass percent:
Radix Saposhnikoviae 25% ~ 35%, Herba Schizonepetae 11% ~ 25%, Rhizoma Et Radix Notopterygii 11% ~ 25%, Radix Angelicae Pubescentis 5% ~ 15%, Flos Carthami 5% ~ 15%, Herba Xanthii 5% ~ 15%, Pyrola rotundifolia ssp.chinensis 2% ~ 6%, the mass percent summation of above component is 100%.
2. preparation method for the treatment of rheumatism, rheumatoid Chinese medicine composition, specifically implement according to following steps:
Step 1
According to mass percent, take by weighing 25% ~ 35% Radix Saposhnikoviae, 11% ~ 25% Herba Schizonepetae, 11% ~ 25% Rhizoma Et Radix Notopterygii, 5% ~ 15% Radix Angelicae Pubescentis, 5% ~ 15% Flos Carthami, 5% ~ 15% Herba Xanthii, 2% ~ 6% Pyrola rotundifolia ssp.chinensis respectively, the mass percent summation of above raw material is 100%;
Step 2
Each raw material pulverizing that step 1 is taken by weighing, fully promptly make after mixing.
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| CN104398719A (en) * | 2014-11-06 | 2015-03-11 | 黎颖 | Traditional Chinese medicinal composition for treating edema, and preparation method thereof |
| CN111588781A (en) * | 2020-07-13 | 2020-08-28 | 深圳市华城大业实业有限公司 | Neck and shoulder strain rehabilitation essential oil for physique of wind-cold obstructing collaterals and preparation method thereof |
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- 2011-07-22 CN CN2011102067591A patent/CN102258602B/en not_active Expired - Fee Related
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| CN101172148A (en) * | 2006-11-03 | 2008-05-07 | 梁振兴 | Pharmaceutical composition for treating bone fracture, dislocation and soft tissue injury, and preparation method thereof |
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| CN104398719A (en) * | 2014-11-06 | 2015-03-11 | 黎颖 | Traditional Chinese medicinal composition for treating edema, and preparation method thereof |
| CN111588781A (en) * | 2020-07-13 | 2020-08-28 | 深圳市华城大业实业有限公司 | Neck and shoulder strain rehabilitation essential oil for physique of wind-cold obstructing collaterals and preparation method thereof |
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| CN102258602B (en) | 2012-11-07 |
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