CN102643274B - 水溶性四唑盐 - Google Patents
水溶性四唑盐 Download PDFInfo
- Publication number
- CN102643274B CN102643274B CN201210102974.1A CN201210102974A CN102643274B CN 102643274 B CN102643274 B CN 102643274B CN 201210102974 A CN201210102974 A CN 201210102974A CN 102643274 B CN102643274 B CN 102643274B
- Authority
- CN
- China
- Prior art keywords
- alkyl
- methyl
- hydrogen
- tetrazolium salts
- trimethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 0 CN(*O*1C=CC([N+](N(*=C(c2ccccc2)N)c2nc(*)c(*)[s]2)=I)=CC=C1)OC Chemical compound CN(*O*1C=CC([N+](N(*=C(c2ccccc2)N)c2nc(*)c(*)[s]2)=I)=CC=C1)OC 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
- Y10T436/144444—Glucose
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
Description
实施例编号(平衡离子) | 溶解度(mM) |
1(溴代亚硝酸根) | 33 |
2(溴代四氟硼酸根) | 5 |
3(溴代亚硝酸根) | 9 |
4(溴代亚硝酸根) | 167 |
5(溴代亚硝酸根) | 5 |
6(二溴代亚硝酸根) | 181 |
7(二溴代亚硝酸根) | 169 |
8(二溴代亚硝酸根) | 290 |
9(三溴离子) | 260 |
WST-4 | 118 |
HTC-045 | 21 |
改性的HTC-045 | 8 |
Claims (16)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64389305P | 2005-01-14 | 2005-01-14 | |
US60/643,893 | 2005-01-14 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN200680004439.5A Division CN101115750A (zh) | 2005-01-14 | 2006-01-13 | 水溶性四唑盐 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102643274A CN102643274A (zh) | 2012-08-22 |
CN102643274B true CN102643274B (zh) | 2015-02-18 |
Family
ID=36337495
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN200680004439.5A Pending CN101115750A (zh) | 2005-01-14 | 2006-01-13 | 水溶性四唑盐 |
CN201210102974.1A Expired - Fee Related CN102643274B (zh) | 2005-01-14 | 2006-01-13 | 水溶性四唑盐 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN200680004439.5A Pending CN101115750A (zh) | 2005-01-14 | 2006-01-13 | 水溶性四唑盐 |
Country Status (12)
Country | Link |
---|---|
US (2) | US7767822B2 (zh) |
EP (1) | EP1851215B1 (zh) |
JP (2) | JP5592058B2 (zh) |
CN (2) | CN101115750A (zh) |
BR (1) | BRPI0606698A2 (zh) |
CA (1) | CA2594813A1 (zh) |
HK (1) | HK1174910A1 (zh) |
MX (1) | MX2007008565A (zh) |
NO (1) | NO20074133L (zh) |
RU (1) | RU2400481C2 (zh) |
TW (1) | TW200637857A (zh) |
WO (1) | WO2006076619A1 (zh) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2007008565A (es) | 2005-01-14 | 2007-09-07 | Bayer Healthcare Llc | Sales de tetrazolio solubles en agua. |
GB201017547D0 (en) | 2010-10-18 | 2010-12-01 | Univ Cardiff | Method and device for the detection of sulphur containing species |
MY189494A (en) * | 2011-03-31 | 2022-02-16 | Genentech Inc | Methods of administering beta7 integrin antagonists |
WO2017090631A1 (ja) * | 2015-11-24 | 2017-06-01 | 国立大学法人 東京大学 | 細胞外代謝物を検出するための蛍光プローブ及び当該蛍光プローブを用いるスクリーニング方法 |
WO2017134878A1 (ja) | 2016-02-04 | 2017-08-10 | テルモ株式会社 | 血糖値測定試薬、血糖値測定チップ、及び血糖値測定装置セット |
JP6947736B2 (ja) * | 2016-09-14 | 2021-10-13 | テルモ株式会社 | 2−置換ベンゾチアゾリル−3−置換フェニル−5−置換スルホ化フェニル−2h−テトラゾリウム塩、ならびに当該塩を含む生体成分濃度測定用試薬および当該塩を用いる生体成分濃度の測定方法 |
CN110603333A (zh) | 2016-12-23 | 2019-12-20 | 赛录科试诊断公司 | 用于改进的快速抗微生物剂敏感性测试的方法 |
CN108872227B (zh) * | 2018-08-30 | 2021-07-06 | 河南省科学院高新技术研究中心 | 一种快速鉴别温县铁棍山药的试剂及其鉴别方法 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2073600A (en) | 1933-12-30 | 1937-03-16 | Ig Farbenindustrie Ag | Heterocyclic hydrazines |
DE2147466C3 (de) | 1971-09-23 | 1980-06-26 | Boehringer Mannheim Gmbh, 6800 Mannheim | 5- (4-N-trimethyl-ammonium-phenyl) tetrazoliumsalze |
JPS603396B2 (ja) * | 1981-12-26 | 1985-01-28 | 株式会社 同仁化学研究所 | テトラゾリウム塩化合物およびその化合物を用いる脱水素酵素の吸光光度定量法 |
US5196314A (en) | 1986-04-04 | 1993-03-23 | Boehringer Mannheim Gmbh | Process and reagent for the determination of substrates or enzyme activities |
US5290536A (en) | 1990-09-19 | 1994-03-01 | Miles Inc. | Phenyl substituted 2-thiazolyl tetrazolium salt indicators |
CA2049209C (en) | 1990-09-19 | 1992-03-20 | Jurgen Kocher | Phenyl-substituted 2-thiazolyl tetrazolium salt indicators |
CA2049230C (en) * | 1990-09-19 | 1999-10-19 | Robert P. Hatch | 2-benzothiazolyl tetrazolium salt indicators |
US5126275A (en) | 1990-09-19 | 1992-06-30 | Miles Inc. | Analytical method using tetrazolium salt indicators having a reflectance plateau |
US5300637A (en) | 1990-09-19 | 1994-04-05 | Miles Inc. | 2-benzothiazolyl tetrazolium salt indicators |
CA2049237C (en) * | 1990-09-19 | 1999-10-19 | Gunther Beck | 2-thiazolyl tetrazolium salt indicators |
US5185450A (en) | 1991-02-19 | 1993-02-09 | University Of South Florida | Tetrazolium compounds for cell viability assays |
US5250695A (en) * | 1992-06-15 | 1993-10-05 | Miles Inc. | Use of specific counteranions to modify the solubility of tetrazolium salts |
US5360595A (en) * | 1993-08-19 | 1994-11-01 | Miles Inc. | Preparation of diagnostic test strips containing tetrazolium salt indicators |
DE19605448A1 (de) | 1996-02-15 | 1997-08-21 | Bayer Ag | Elektrochromes System |
JP2757348B2 (ja) | 1996-04-18 | 1998-05-25 | 株式会社同仁化学研究所 | 新規水溶性テトラゾリウム塩化合物 |
DE19631728A1 (de) | 1996-08-06 | 1998-02-12 | Bayer Ag | Elektrochrome Anzeigevorrichtung |
DE19631729A1 (de) | 1996-08-06 | 1998-02-12 | Bayer Ag | Elektrochromes System |
GB9703468D0 (en) | 1997-02-19 | 1997-04-09 | Browne Albert Ltd | Steam sterilization process indicator |
US6586199B2 (en) | 2001-11-20 | 2003-07-01 | Lifescan, Inc. | Stabilized tetrazolium reagent compositions and methods for using the same |
US6913878B2 (en) | 2003-01-06 | 2005-07-05 | The University Of North Carolina At Chapel Hill | Method of detecting DNA single strand breaks |
MX2007008565A (es) | 2005-01-14 | 2007-09-07 | Bayer Healthcare Llc | Sales de tetrazolio solubles en agua. |
-
2006
- 2006-01-13 MX MX2007008565A patent/MX2007008565A/es not_active Application Discontinuation
- 2006-01-13 BR BRPI0606698-4A patent/BRPI0606698A2/pt not_active IP Right Cessation
- 2006-01-13 WO PCT/US2006/001307 patent/WO2006076619A1/en active Application Filing
- 2006-01-13 CA CA002594813A patent/CA2594813A1/en not_active Abandoned
- 2006-01-13 US US11/794,782 patent/US7767822B2/en not_active Expired - Fee Related
- 2006-01-13 JP JP2007551415A patent/JP5592058B2/ja active Active
- 2006-01-13 TW TW095101499A patent/TW200637857A/zh unknown
- 2006-01-13 CN CN200680004439.5A patent/CN101115750A/zh active Pending
- 2006-01-13 EP EP06718389.7A patent/EP1851215B1/en not_active Not-in-force
- 2006-01-13 RU RU2007130854/04A patent/RU2400481C2/ru not_active IP Right Cessation
- 2006-01-13 CN CN201210102974.1A patent/CN102643274B/zh not_active Expired - Fee Related
-
2007
- 2007-08-10 NO NO20074133A patent/NO20074133L/no not_active Application Discontinuation
-
2010
- 2010-06-16 US US12/816,793 patent/US7897331B2/en not_active Expired - Fee Related
-
2013
- 2013-02-08 JP JP2013023172A patent/JP2013136603A/ja not_active Withdrawn
- 2013-02-18 HK HK13102007.2A patent/HK1174910A1/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US20080125471A1 (en) | 2008-05-29 |
CN102643274A (zh) | 2012-08-22 |
NO20074133L (no) | 2007-10-15 |
WO2006076619A1 (en) | 2006-07-20 |
JP2013136603A (ja) | 2013-07-11 |
CN101115750A (zh) | 2008-01-30 |
EP1851215B1 (en) | 2013-12-18 |
US20100255506A1 (en) | 2010-10-07 |
RU2007130854A (ru) | 2009-02-20 |
TW200637857A (en) | 2006-11-01 |
MX2007008565A (es) | 2007-09-07 |
BRPI0606698A2 (pt) | 2009-07-14 |
US7767822B2 (en) | 2010-08-03 |
US7897331B2 (en) | 2011-03-01 |
JP2008526990A (ja) | 2008-07-24 |
CA2594813A1 (en) | 2006-07-20 |
EP1851215A1 (en) | 2007-11-07 |
JP5592058B2 (ja) | 2014-09-17 |
HK1174910A1 (zh) | 2013-06-21 |
RU2400481C2 (ru) | 2010-09-27 |
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Ref country code: HK Ref legal event code: DE Ref document number: 1174910 Country of ref document: HK |
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TR01 | Transfer of patent right |
Effective date of registration: 20161222 Address after: Basel, Switzerland Patentee after: BAYER HEALTHCARE LLC Address before: American New York Patentee before: Bayer Healthcare LLC |
|
TR01 | Transfer of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150218 Termination date: 20220113 |
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CF01 | Termination of patent right due to non-payment of annual fee |