CN102631492A - Chinese medicinal composition for improving immunity and resisting fatigue - Google Patents
Chinese medicinal composition for improving immunity and resisting fatigue Download PDFInfo
- Publication number
- CN102631492A CN102631492A CN2012101219695A CN201210121969A CN102631492A CN 102631492 A CN102631492 A CN 102631492A CN 2012101219695 A CN2012101219695 A CN 2012101219695A CN 201210121969 A CN201210121969 A CN 201210121969A CN 102631492 A CN102631492 A CN 102631492A
- Authority
- CN
- China
- Prior art keywords
- cordyceps
- compositions
- spirulina
- radix ginseng
- stigma croci
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 39
- 230000036039 immunity Effects 0.000 title claims abstract description 20
- 241000190633 Cordyceps Species 0.000 claims abstract description 79
- 240000002900 Arthrospira platensis Species 0.000 claims abstract description 31
- 235000016425 Arthrospira platensis Nutrition 0.000 claims abstract description 31
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 27
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 27
- 235000008434 ginseng Nutrition 0.000 claims abstract description 27
- 229940082787 spirulina Drugs 0.000 claims abstract description 27
- 230000000694 effects Effects 0.000 claims abstract description 20
- 230000036541 health Effects 0.000 claims abstract description 9
- 241000208340 Araliaceae Species 0.000 claims description 27
- 239000003814 drug Substances 0.000 claims description 21
- 201000001881 impotence Diseases 0.000 claims description 13
- 238000002360 preparation method Methods 0.000 claims description 13
- 208000010228 Erectile Dysfunction Diseases 0.000 claims description 8
- 230000002929 anti-fatigue Effects 0.000 claims description 8
- 210000003734 kidney Anatomy 0.000 claims description 7
- 239000002994 raw material Substances 0.000 claims description 4
- 239000002552 dosage form Substances 0.000 claims description 2
- 230000002708 enhancing effect Effects 0.000 abstract description 9
- 244000124209 Crocus sativus Species 0.000 abstract 1
- 235000015655 Crocus sativus Nutrition 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 235000013974 saffron Nutrition 0.000 abstract 1
- 239000004248 saffron Substances 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 22
- 241000699670 Mus sp. Species 0.000 description 18
- 230000006870 function Effects 0.000 description 13
- 241000699666 Mus <mouse, genus> Species 0.000 description 12
- 239000002775 capsule Substances 0.000 description 12
- 238000000034 method Methods 0.000 description 11
- 230000037396 body weight Effects 0.000 description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 9
- 239000000843 powder Substances 0.000 description 9
- 239000002904 solvent Substances 0.000 description 9
- 239000003826 tablet Substances 0.000 description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 238000002474 experimental method Methods 0.000 description 8
- 210000000952 spleen Anatomy 0.000 description 7
- 229940079593 drug Drugs 0.000 description 6
- 239000000284 extract Substances 0.000 description 6
- 238000005728 strengthening Methods 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 230000036737 immune function Effects 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 210000004072 lung Anatomy 0.000 description 5
- 238000012545 processing Methods 0.000 description 5
- 230000001568 sexual effect Effects 0.000 description 5
- 230000009182 swimming Effects 0.000 description 5
- LOTKRQAVGJMPNV-UHFFFAOYSA-N 1-fluoro-2,4-dinitrobenzene Chemical compound [O-][N+](=O)C1=CC=C(F)C([N+]([O-])=O)=C1 LOTKRQAVGJMPNV-UHFFFAOYSA-N 0.000 description 4
- 241001264174 Cordyceps militaris Species 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 230000001939 inductive effect Effects 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 230000000242 pagocytic effect Effects 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 210000002966 serum Anatomy 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 3
- 206010011224 Cough Diseases 0.000 description 3
- 206010033888 Paraphilia Diseases 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 238000009835 boiling Methods 0.000 description 3
- 229910052799 carbon Inorganic materials 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 230000003203 everyday effect Effects 0.000 description 3
- 239000003228 hemolysin Substances 0.000 description 3
- 210000004698 lymphocyte Anatomy 0.000 description 3
- 238000012856 packing Methods 0.000 description 3
- 210000003024 peritoneal macrophage Anatomy 0.000 description 3
- 239000000546 pharmaceutical excipient Substances 0.000 description 3
- 210000001541 thymus gland Anatomy 0.000 description 3
- 230000007306 turnover Effects 0.000 description 3
- 206010010071 Coma Diseases 0.000 description 2
- 241000422920 Cordyceps gunnii Species 0.000 description 2
- 241000192700 Cyanobacteria Species 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 241000287828 Gallus gallus Species 0.000 description 2
- 206010018910 Haemolysis Diseases 0.000 description 2
- 108010006464 Hemolysin Proteins Proteins 0.000 description 2
- 230000001093 anti-cancer Effects 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 239000012752 auxiliary agent Substances 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 239000003937 drug carrier Substances 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 210000003743 erythrocyte Anatomy 0.000 description 2
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 238000000227 grinding Methods 0.000 description 2
- 235000013402 health food Nutrition 0.000 description 2
- 230000008588 hemolysis Effects 0.000 description 2
- 239000012669 liquid formulation Substances 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 239000008194 pharmaceutical composition Substances 0.000 description 2
- 238000010298 pulverizing process Methods 0.000 description 2
- 238000007670 refining Methods 0.000 description 2
- 238000010992 reflux Methods 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- 230000009466 transformation Effects 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 206010061623 Adverse drug reaction Diseases 0.000 description 1
- 241000726128 Aeshna Species 0.000 description 1
- 241001136249 Agriotes lineatus Species 0.000 description 1
- 206010063659 Aversion Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241001414824 Cercopidae Species 0.000 description 1
- 208000017667 Chronic Disease Diseases 0.000 description 1
- 241001480006 Clavicipitaceae Species 0.000 description 1
- 241000756943 Codonopsis Species 0.000 description 1
- 241001422921 Cordyceps kyushuensis Species 0.000 description 1
- 241000890155 Cordyceps takaomontana Species 0.000 description 1
- 241000596148 Crocus Species 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- 241001124144 Dermaptera Species 0.000 description 1
- 208000035240 Disease Resistance Diseases 0.000 description 1
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 208000000616 Hemoptysis Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 241000234269 Liliales Species 0.000 description 1
- 206010024642 Listless Diseases 0.000 description 1
- 241000254043 Melolonthinae Species 0.000 description 1
- 241000319345 Metacordyceps liangshanensis Species 0.000 description 1
- 241000794913 Metarhizium martiale Species 0.000 description 1
- 241000648515 Ophiocordyceps gracilioides Species 0.000 description 1
- 241001625030 Ophiocordyceps oxycephala Species 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 241000208343 Panax Species 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 206010039101 Rhinorrhoea Diseases 0.000 description 1
- 101150084989 Speg gene Proteins 0.000 description 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 1
- 208000037386 Typhoid Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 208000005946 Xerostomia Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 210000002534 adenoid Anatomy 0.000 description 1
- 238000003915 air pollution Methods 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 230000002605 anti-dotal effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 210000000628 antibody-producing cell Anatomy 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000005784 autoimmunity Effects 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 210000003323 beak Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 206010013781 dry mouth Diseases 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 239000000469 ethanolic extract Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 210000004709 eyebrow Anatomy 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 238000007667 floating Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 235000020710 ginseng extract Nutrition 0.000 description 1
- 210000004209 hair Anatomy 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 208000019423 liver disease Diseases 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000001662 opsonic effect Effects 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000003236 psychic effect Effects 0.000 description 1
- 230000001107 psychogenic effect Effects 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 238000009613 pulmonary function test Methods 0.000 description 1
- 208000008128 pulmonary tuberculosis Diseases 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000009666 routine test Methods 0.000 description 1
- 238000007665 sagging Methods 0.000 description 1
- 238000007560 sedimentation technique Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 235000015961 tonic Nutrition 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 229960000716 tonics Drugs 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a health care product composition for improving the immunity of a human organism and resisting fatigue. The composition consists of the active ingredients of ginseng, saffron, spirulina and cordyceps. The composition has the effects of enhancing the immunity of the organism, resisting fatigue and building the body of a patient, and has remarkable curative effects and mild effects.
Description
Technical field
The present invention relates to a kind of collaborative Chinese medicine composition that improves body immunity, resisting fatigue and kidney invigorating and Yang strengthening function that has.
Technical background
Along with socioeconomic continuous development; The raising day by day of people's living standard; People increase the degree of keeping a grip on of health gradually; Live in now all be that we receive many outside threats easily at everyone health, comprise air pollution, video pollution, environmental pollution, operating pressure, economic pressures, bacterial virus, improper diet or the like.Moreover, because the variation of city work, rhythm of life is easy to make the people to produce confirmed fatigue, i.e. sub-health state, the factor of all these unfavorable health can make us usually that spirit can not be concentrated, hypomnesis, often indolent and listless, old and feeble ahead of time.Therefore improve autoimmunity, the ability that strengthens the various unfavorable health factors of antagonism is most important.
The present health product that are used for enhancing human body immunity power on the market are of a great variety, but action effect is uneven.
Summary of the invention
The technical problem that the present invention will solve is: the Chinese medicine composition that the purpose of this invention is to provide a kind of enhancing human body immunity power, resisting fatigue and kidney invigorating and Yang strengthening function.Through being main Chinese crude drug with Radix Ginseng, Stigma Croci, spirulina and Cordyceps, through mutual synergistic function, in the hope of disease resistance enhancemen, enhance immunity effect, the engineering of alleviating physical fatigue and kidney invigorating and Yang strengthening function.
For solving the problems of the technologies described above; The present invention provides a kind of collaborative body immunity, antifatigue Halth-care composition of improving that have; It is characterized in that described compositions comprises a kind of Halth-care composition that has Synergistic raising human body immunity of organisms, resisting fatigue and have kidney invigorating and Yang strengthening function of active component, is characterized in that described compositions comprises Radix Ginseng, Stigma Croci, spirulina, Cordyceps.In the active component by weight: Radix Ginseng 3-65 part, Stigma Croci 2-60 part, spirulina 4-65 part, Cordyceps 4-65 part.Preferably, Radix Ginseng 4-50 part, Stigma Croci 3-45 part, spirulina 7-50 part, Cordyceps 8-45 part.
Preferably, the weight proportion of each component is: 65 parts of Radix Ginsengs, 60 parts of Stigma Crocis, 65 parts of spirulinas, 65 parts of Cordycepses.
Preferably, the weight proportion of each component is: Radix Ginseng is 3 parts, and Stigma Croci is 2 parts, 4 parts of spirulinas, 4 parts of Cordycepses.
The weight proportion of preferred each component is: 20 parts of Radix Ginsengs, 12 parts of Stigma Crocis, 25 parts of spirulinas, 15 parts of Cordycepses.
The weight proportion of preferred each component is: 50 parts of Radix Ginsengs, 45 parts of Stigma Crocis, 50 parts of spirulinas, 45 parts of Cordycepses.
Radix Ginseng: related Radix Ginseng is meant the general name of a kind of herbaceos perennial of the Umbellales Araliaceae Radix Ginseng Panax of family among the present invention, comprises Radix Ginseng Rubra, Radix Ginseng, Radix Panacis Quinquefolii (Radix Panacis Quinquefolii), Radix Glehniae, Radix Codonopsis and Radix Pseudostellariae etc.Radix Ginseng among the present invention comprises through processing refinement back Radix Ginseng extract, the various forms in grinding descendant's pure extract powder or Radix Ginseng growth course.
Stigma Croci: involved in the present invention to Stigma Croci (claiming Stigma Croci, Stigma Croci again), be the perennial flowers of a kind of Liliales Iridaceae crocus.Stigma Croci among the present invention comprises crocein powder after grinding, obtains Stigma Croci extracts or croceous other processing forms through various processes.
Spirulina: involved in the present invention to spirulina be meant the one type of rudimentary plant that belongs in Cyanophyta, Cyanophyceae, hormocystangium order, Oscillariaceae, the Spirullina, mainly comprise spirulina maxim, spirulina plalensis.Spirulina among the present invention comprises other processing forms of refining rear screw algae extract or spirulina through processing.
Cordyceps: related Cordyceps is meant the fungus (Cordyceps) and the bacterium worm coalition that larva forms of Clavicipitaceae among the present invention under specific condition, comprising: Cordyceps, Cordyceps hawkesii Gary, Cordyceps liangshanensis Zang Hu et Liu, Xinjiang Cordyceps, branch Cordyceps, the leaves of pulse plants restrain Cordyceps, Cordyceps militaris (L.) Link., Wuyi Mountain Cordyceps, dragon's cave-stalactite cave Cordyceps, Zhangjiajie Cordyceps, big cat head Cordyceps, many shells Cordyceps, gentle handle Cordyceps, sagging Cordyceps, Jiangxi Cordyceps, Sichuan Cordyceps, Cordyceps oxycephala, crust grace Cordyceps, Guizhou Cordyceps, Chishui Cordyceps, Dermaptera Cordyceps, intend Bu Banke Cordyceps, Cordyceps martialis Speg., Lou Shan Cordyceps, Mus tail Cordyceps, green nuclear Cordyceps, moorland Cordyceps, luxuriant blue Cordyceps, BUSHICHONGCAO, Cordyceps takaomontana, yellowish Cordyceps militaris (L.) Link., bulb Cordyceps, chafer Cordyceps, Mantidis Cordyceps, froghopper Cordyceps, handle shell Cordyceps, intend luxuriant blue Cordyceps, Cordyceps gracilioides, hair Cordyceps, wireworm Cordyceps, Japanese Cordyceps, Xin Kelai Cordyceps, beak shell Cordyceps, intend dark green Cordyceps, high eyebrow Cordyceps, FENBEICHONGCAO, Dayi Cordyceps, fork-tail Cordyceps, Caulis cyatheae spinulosae Cordyceps, Aeschna melanictera Cordyceps, ant Cordyceps, Luo Baici Cordyceps, Cordyceps kyushuensis, buttress shaft Cordyceps, DAISHICHONGCAO, distortion Cordyceps, rice mountain Cordyceps, two shuttle spore Cordyceps, Cordyceps gunnii (Berk.) Berk. etc.Worm powder after Cordyceps among the present invention comprises Cordyceps and grinds, refine the back Cordyceps extract, or have a form in each growth course of Cordyceps through processing.Cordyceps has the function that tonifying the lung kidney, cough-relieving are coughed, benefit is deficient, support vital essence.According to clinical research, Cordyceps has ten big functions and has foster lung yin, kidney-replenishing, relieving cough and resolving phlegm, anticancer anti-old effect; Be the article of flat nourishing YIN sun, all do not have institute and avoid that (men and women, old and young can both eat, and are the suitable the widest tonics of crowd; And need not avoid certain food, health is had much tonification, mend marrow lung benefiting kidney; And the property of medicine is gentle, does not attend a meeting like the people that the people is produced is scorching, the benefit of Radix Ginseng is arranged and does not have the evil of Radix Ginseng).Can be used for the pulmonary tuberculosis hemoptysis, diseases such as impotence and seminal emission.
The definition of " collaborative improve " is appreciated that to after several kinds of medical materials combinations among the present invention, the raising of its drug effect during with respect to independent the use; Drug effect is more lasting; Compositions produces beyond thought effect in new control or healthcare field.
In the component of the present invention, Cordyceps property is put down sweet in the mouth, has the function that kidney-replenishing, cough-relieving are coughed, benefit is deficient, support vital essence.The Radix Ginseng strongly invigorating primordial QI, multiple arteries and veins takes off invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, the Fructus Alpiniae Oxyphyllae of calming the nerves, strong taste admittedly.Stigma Croci sweet in the mouth property is flat, ability blood circulation promoting and blood stasis dispelling, dispersing stagnation and relieving accumulation of pathogens, pain relieving, resisting fatigue.Be used to treat troubled thoughts pent-up, the chest and diaphragm painful abdominal mass is vexed, spits blood, and typhoid fever is gone mad, and is frightened fear in a trance, blood circulation promoting and blood stasis dispelling, removing pathogenic heat from blood and toxic substance from the body, resolving stagnation for tranquilization and the soothing liver-QI that is good for the stomach.Spirulina has the opsonic immunity function, cholesterol reducing, promoting digestion, protecting liver, anticancer, antidotal effect.
The inventor finds through test; Compositions of the present invention has remarkable role in synergy on raising body immunity, antifatigue pathology; Have outside the body immunity of raising, the antifatigue effect like compositions of the present invention, have the effect of improving male's sexual simultaneously.These single agent are that single agent is incomparable to the action effect of some function of human body after through a certain proportion of compositions.
Compositions of the present invention can directly be pulverized or through the active component of the refining compositions as treatment of the extraction of the conventional extractive technique in this area such as decoction and alcohol sedimentation technique or ethanol extract from water precipitation.Said active component can be processed various pharmaceutical formulations with pharmaceutically acceptable carrier or excipient composition, as is how granular tablet, granule, capsule, or oral liquid etc.According to the use needs, compositions of the present invention also can be processed into slow releasing preparation or quick releasing formulation.Wherein said pharmaceutically acceptable carrier or excipient are selected according to different dosage forms.These used carriers or excipient can determine for the those of ordinary skill of pharmaceutical field.
The method for preparing of oral liquid, can but not only be confined to following a kind of, after active component is mixed; Decoction liquor is filtered in decocte with water, obtains solution; The gained solution concentration is obtained extractum, then gained extractum be dissolved in 5-10 times of weight of extractum weight concentration in the ethanol water according to weight meter 95%, mix; Quantitatively packing obtains oral liquid formulations.
The method for preparing of tablet is that the active component mixture is sieved, and behind the auxiliary agent pulverizing commonly used with preparing tablet, abundant mix homogeneously, crosses the 40-80 eye mesh screen, through tabletting the direct machine of dry powder is pressed into tablet.
The preparation technology of capsule preparations can for, the active component mixture is sieved, pulverizing with preparation tablet auxiliary agent commonly used, fully behind the mix homogeneously, crossing the 40-80 eye mesh screen, through granulating, drying is irritated capsule after the operations such as granulate, polishing, packing gets product.
The invention has the beneficial effects as follows:
Pharmaceutical composition of the present invention has benefiting QI for strengthening the superficies; The effect of human body immunity improving power; Medicine of the present invention is not warm not dry, has invigorating spleen and reinforcing stomach, improves microcirculation in human body, the effect of wet dissipation eliminating impediment, enhancing immunity, resisting fatigue, antiviral, strengthening body, and is evident in efficacy; Action temperature with, have no side effect.This production of medicine technology is simple, be easy to take, and is a kind of ideal raising human immunity, antifatigue medicine.
Detailed description of the preferred embodiments
Following examples have been explained various aspects of the present invention.They only in order to explanation, not delimit the scope of the invention.
Embodiment 1: contain the capsule that the people participates in Stigma Croci, spirulina and Cordyceps
Radix Ginseng 65 grams, Stigma Croci 60 grams, spirulina 65 grams, Cordyceps 65 grams.
Above-mentioned Chinese medicine was soaked 40 minutes, and it is important that the water surface is higher than raw material, adds water inventory and be 8 times of total dose, the little fire in back that the boils attitude of boiling; Keep liquid level and be higher than raw material Chinese medicine height, decocted 2 hours, cross leaching filtrating, add 6 times water of total dose again; The back little fire attitude of boiling of boiling is kept liquid level and is higher than raw material Chinese medicine height, decocts 2 hours, filters twice filtrating of merging; Through concentrating under reduced pressure (pressure 0.06MPa, 65 ℃ of temperature) to dried cream, pulverize; Through 300 mesh sieves, add the magnesium stearate of gross weight 2%, incapsulate and get final product.
Embodiment 2: contain the tablet that the people participates in Stigma Croci, spirulina and Cordyceps
Radix Ginseng 3 grams, Stigma Croci 2 grams, spirulina 4 grams, Cordyceps 4 grams.
Above-mentioned Chinese crude drug is dried and crushed into coarse powder, with the ethanol of 50-60% be solvent 60-70 ℃ of reflux, extract,, extracting solution is being gone out behind the ethanol, cryoconcentration becomes thick extractum, drying is ground into fine powder, sieves, mixing is granulated, and is pressed into tablet.
Embodiment 3: contain the capsule that the people participates in Stigma Croci, spirulina and Cordyceps militaris (L.) Link.
Radix Ginseng 20 grams, Stigma Croci 12 grams, spirulina 25 grams, Cordyceps militaris (L.) Link. 15 grams.
Above-mentioned Chinese crude drug is dried and crushed into fine powder, sieves, mixing is packed into firmly softgel shell, makes Chinese medicine composition of the present invention.
Embodiment 4: contain the oral liquid that the people participates in Stigma Croci, spirulina and Cordyceps
Radix Ginseng 50 grams, Stigma Croci 45 grams, spirulina 50 grams, Cordyceps 50 grams.
After the said components mixing, decoction liquor is filtered in decocte with water; Obtain solution, the gained solution concentration obtained extractum, then gained extractum be dissolved in 5-10 times of weight of extractum weight concentration in the ethanol water according to weight meter 95%; Mix, quantitatively packing obtains oral liquid formulations.
Embodiment 5: contain the tablet that the people participates in Stigma Croci, spirulina and Cordyceps
Radix Ginseng 17 grams, Stigma Croci 13 grams, spirulina 45 grams, Cordyceps 12 grams
Above-mentioned Chinese crude drug is dried and crushed into coarse powder, with the ethanol of 50-60% be solvent 60-70 ℃ of reflux, extract,, extracting solution is being gone out behind the ethanol, cryoconcentration becomes thick extractum, drying is ground into fine powder, sieves, mixing is granulated, and is pressed into tablet.
Test example 1: the present invention tests effect of immunologic function
1, the product of testing product: embodiment 1, embodiment 2, embodiment 3, embodiment 4 and embodiment 5 is a sample.
2, animal is used in detection: mice, rat, male and female half and half.
3, test basis: Ministry of Public Health " health food check and assessment technique standard " (2003 editions)
4, test item:
4.1 body weight, thymus/body weight ratio, spleen/body weight ratio
4.2 the inductive mouse spleen lymphocyte transformation experiment of comA (mtt assay)
4.3 the tardy paraphilia reaction of the inductive mice of dinitrofluorobenzene (DTH)
4.4 antibody-producting cell detects (Jerne improves slide method)
4.5 serum hemolysin test
4.6 mice carbon clearance test
4.7 Turnover of Mouse Peritoneal Macrophages is engulfed chicken red blood cell experiment (dripping the sheet method)
4.8 the NK cytoactive is measured
5, testing result and judgement
5.1 the body weight of laboratory animal; Thymus/body weight ratio, the testing result of spleen/body weight ratio shows, under this experimental condition; Institute's full pattern article 500,1000, kg during (be equivalent to respectively be grown up per kg body weight per day recommended intake 5 times, 10 times, 30 times) dosage; Five groups of samples are to the body weight of animal, thymus/body weight ratio, and spleen/body weight ratio is not all seen obvious influence.
5.2 the inductive mouse spleen lymphocyte transformation experiment of comA (mtt assay) is the result show, under this experiment condition, each dose groups optical density difference and solvent control class value relatively all do not have statistical significant difference (P＞0.05).The prompting sample does not have the mouse lymphocyte of enhancing multiplication capacity.
5.3 the tardy paraphilia reaction of the inductive mice of dinitrofluorobenzene is (DTH) result show, under this experiment condition, each dose groups optical density difference and solvent control class value relatively all do not have statistical significant difference (P＞0.05).The prompting sample has the tardy paraphilia reagentia of mice that the enhancing dinitrofluorobenzene causes.The test dose group is positive, and the prompting sample can strengthen the mouse cell immunologic function.
5.4 detecting (Jerne improves slide method) result, antibody-producting cell shows; Under this experimental condition; Each dose groups hemolysis plaque number average is higher than the solvent control class value; And low, middle dose groups has statistically-significant difference (P＜0.05), and the prompting sample has the ability that mice produces antibody producing cells that strengthens.
5.5 the serum hemolysin result of the test shows that under this experiment condition, each dose groups mice serum half hemolysis value and solvent control class value relatively all do not have statistically-significant difference (P＞0.05).The prompting sample does not have the ability that mice produces serum hemolysin that strengthens.The dose groups of a test is positive, and the prompting sample can strengthen the mouse humoral immune function.
5.6 the clearance test of mice carbon is the result show, under this experiment condition, each dose groups mice engulf tree planting A and solvent control class value relatively, all do not have statistical significant difference (P＞0.05).Prompting sample five strengthens the effect that carbon is cleaned up ability.
5.7 engulfing chicken red blood cell experiment (dripping the sheet method) result, Turnover of Mouse Peritoneal Macrophages shows; Under this experimental condition; The monokaryon of each sample and each dose groups mice-macrophage phagocytic percentage rate and phagocytic index and solvent control class value relatively all do not have statistical significant difference (P＞0.05).Prompting sample five strengthens the effect of Turnover of Mouse Peritoneal Macrophages phagocytic activity.Result of the test is all negative, and the prompting sample does not have enhancing mouse monokaryon-macrophage phagocytic function.
5.8 measuring the result, the NK cytoactive shows; Under this experimental condition; The NK cytoactive of each dose groups mice all is higher than the solvent control class value, and high dose group has statistical significant difference (P＜0.05), the effect that the prompting sample has the NK cytoactive that strengthens mice.
Comprehensive above result of the test, according to health food function of enhancing immunity evaluation criterion, 5 samples of prescription of the present invention all have the function of enhancing immunity.
Test example 2: the present invention is to improving the clinical efficacy of immune function of human body
The child: immunologic hypofunction, easy catching a cold, average every month more than twice, or suffer from twice above patient of pneumonia in 1 year.
Elderly patients: suffer from multiple chronic disease, be diagnosed as the patient of syndrome of deficiency of lung qi.
2, the method for administration and the course of treatment:
The preparation of oral embodiment of the invention 1-4 embodiment.Contrast: Stigma Croci capsule, spirulina capsule, Radix Ginseng+spirulina (1: 1) capsule; Stigma Croci+Cordyceps (1: 1) capsule; Cordyceps+Radix Ginseng (1: 1) capsule.
Adult: each 3 examples, every day 3 times.
Child below 6 years old: each 1, every day 2-3 time.
Child more than 6 years old: each 2, each 2-3 time.
Above patient was a course of treatment with one month all, and it treats 1-3 the course of treatment.
3, observational technique:
Carry out blood, urine, just routine test and the heart, pulmonary function test, and observe: heating, aversion to cold, sniffle, pharyngeal symptom and whole body situation and the temperature of having a medical check-up, pharyngeal tonsil, the picture of the tongue pulse condition, therapeutic evaluation is carried out in variations such as fingerprint respectively.
4, therapeutic evaluation
Table one prescription of the present invention improves the clinical observation of immune function of human body
Drug side effect of the present invention: period in a medicine small number of patients xerostomia, outside the dry stool, all there is not any untoward reaction, drug withdrawal or decrement, mouthfeel, dry stool transference cure.
Test example 3: the present invention is to the influence test of mouse anti-reflecting fatigue
Preparation of the present invention (embodiment 1, embodiment 2, embodiment 3, embodiment 4, embodiment 5) is to mouse anti-reflecting fatigue influence test.90 of mices are divided into six groups at random, press the gastric infusion of dosage shown in the table 2, and every day 1 time, continuous 10 days, normal control group and model group gave the equal-volume distilled water, and volume is 20ml/kg.And in first day on-test.After the last administration 1 hour, animal is put into 15 ± 1 ℃ swimming groove, observe mice and put into water and be sink to the water-bed unable again time of floating for continuing swimming time.The result sees that table 2. is visible by table 2 result, and compositions of the present invention can obviously prolong mice low temperature and continue swimming time.
Table 2. preparation of the present invention is to the influence of mice swimming time
Result of the test shows, but preparation significant prolongation mice low temperature of the present invention continues swimming time.Show that the present invention has the antifatigue ability to mice.
Test example 4: the present invention is to impotence patient's clinical treatment
(1) clinical data
2009 are so far, and the preparation that the inventor utilizes embodiment 1, embodiment 2, embodiment 3 and embodiment 5 to make carries out clinical observation treatment to 544 routine impotence patients, wherein, and age 20-30 year, 108 examples; 31-40 year, 137 examples, 41-50 year, 133 examples, 51-60 year, 105 examples, more than 60 years old, 61 examples.Sexual impotence reason: sexual impotence 82 examples due to sexual impotence 68 examples due to psychic impotence 78 examples, nephropathy, hepatopathy, incretion sexual impotence 64 examples, sexual hypofunction (lowly) person 98 examples, psychogenic sexual impotence 56 examples, arteriosclerotic sexual impotence 21 examples, unknown cause sexual impotence 77 examples.Contrast medicament: the single agent capsules of Cordyceps, Cordyceps+spirulina capsule agent (1: 1).
(2) Therapeutic Method
Compositions according to the invention, warm water is for oral administration, and three times on the one, each 3-6g, one after each meal.Calculate treatment time according to the conditions of patients weight, patients with mild was taken 3 months, and the severe case serve on 6 months.
(3) curative effect determinate standard
Cure: after the treatment phase, erection is greater than 90 degree, and success rate of sexual intercourse is more than or equal to 80%.
Produce effects: after the treatment phase, erection is greater than 90 degree, and success rate of sexual intercourse is more than or equal to 50%.
Effectively: after the treatment phase, the erection situation makes moderate progress, and success rate of sexual intercourse is more than or equal to 30%.
Invalid: each item index does not all have improvement before and after the medication.
(4) clinical effectiveness
Clinical trial shows, the present invention has excellent therapeutic effect to impotence patient, reaches more than 90% for patient's total effective rate of age less than 50 years old, along with the increase therapeutic effect at age also decreases, but still has curative effect preferably with comparing.
Claims (6)
1. one kind has the collaborative Halth-care composition that improves human body immunity of organisms, antifatigue effect and kidney invigorating and YANG supporting, it is characterized in that being made up of the raw material that comprises following weight parts: Radix Ginseng 3-65 part, Stigma Croci 2-60 part, spirulina 4-65 part, Cordyceps 4-65 part.
2. according to the compositions of claim 1, it is characterized in that in total active component, by weight: Radix Ginseng 4-50 part, Stigma Croci 3-45 part, spirulina 7-50 part, Cordyceps 8-45 part.
3. according to the compositions of claim 1, it is characterized in that described compositions is the preparation of peroral dosage form.
4. according to the compositions of claim 1-3, it is characterized in that described compositions improves the application in the immunity health medicine in preparation.
5. according to the compositions of claim 1-3, it is characterized in that the application of described compositions in preparation anti-fatigue health-caring medicine.
6. according to the compositions of claim 1-3, it is characterized in that described compositions is in the health product of preparation treatment sexual impotence or the purposes in the medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210121969.5A CN102631492B (en) | 2012-04-24 | 2012-04-24 | Chinese medicinal composition for improving immunity and resisting fatigue |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210121969.5A CN102631492B (en) | 2012-04-24 | 2012-04-24 | Chinese medicinal composition for improving immunity and resisting fatigue |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102631492A true CN102631492A (en) | 2012-08-15 |
| CN102631492B CN102631492B (en) | 2013-08-14 |
Family
ID=46616172
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210121969.5A Active CN102631492B (en) | 2012-04-24 | 2012-04-24 | Chinese medicinal composition for improving immunity and resisting fatigue |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102631492B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105456569A (en) * | 2016-01-31 | 2016-04-06 | 李娜 | Composition comprising cordyceps sinensis and being capable of enhancing functions of human body |
| WO2022142669A1 (en) * | 2020-12-29 | 2022-07-07 | 上海家化联合股份有限公司 | Anti-aging traditional chinese medicine composition, preparation method therefor, use thereof for non-therapeutic purpose, and use thereof in preparation of cosmetic |
-
2012
- 2012-04-24 CN CN201210121969.5A patent/CN102631492B/en active Active
Non-Patent Citations (3)
| Title |
|---|
| 刘绍: "食品与免疫", 《中国食品与营养》 * |
| 王海颖: "中药与免疫的研究概况", 《中医研究》 * |
| 高顺生: "现代中医药方剂在抗运动型疲劳中的应用", 《中国临床康复》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105456569A (en) * | 2016-01-31 | 2016-04-06 | 李娜 | Composition comprising cordyceps sinensis and being capable of enhancing functions of human body |
| WO2022142669A1 (en) * | 2020-12-29 | 2022-07-07 | 上海家化联合股份有限公司 | Anti-aging traditional chinese medicine composition, preparation method therefor, use thereof for non-therapeutic purpose, and use thereof in preparation of cosmetic |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102631492B (en) | 2013-08-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103103099B (en) | A kind of compound Dendrobium huoshanense-cistanchganoderma ganoderma health promoting wine and production technology | |
| CN103549433A (en) | Traditional Chinese medicine health-care food with liver protecting effect | |
| CN112569305A (en) | Mushroom compound polysaccharide composition for improving immunity and preparation method thereof | |
| CN102631494B (en) | Traditional Chinese medicine composition capable of improving immunity and resisting fatigue | |
| CN104055935A (en) | Traditional Chinese medicine composition for improving immunity in synergetic mode | |
| CN102631492B (en) | Chinese medicinal composition for improving immunity and resisting fatigue | |
| CN101347543A (en) | Chinese medicine compound and preparation method thereof | |
| CN102631490B (en) | Traditional Chinese medicine composition capable of improving immunity and resisting fatigue | |
| CN102631498B (en) | Chinese medicinal composition | |
| CN111298020B (en) | Traditional Chinese medicine composition with anti-fatigue effect and preparation method and application thereof | |
| CN102631506B (en) | Traditional Chinese medicine composition capable of improving immunity and resisting fatigue | |
| CN102631486B (en) | Health care composition | |
| CN102631487B (en) | Traditional Chinese medicine composition capable of improving immunity and resisting fatigue | |
| CN106924581A (en) | It is a kind of to treat medicinal liquor of stomachache and preparation method thereof | |
| CN102120000B (en) | Composition of effective parts of traditional Chinese medicine preparation for resisting Coxsackie virus B and preparation method thereof | |
| CN101199741B (en) | Capsule and preparing method thereof | |
| CN102631488B (en) | Traditional Chinese medicine composition capable of improving immunity and resisting fatigue | |
| CN107536016B (en) | A nutritional food for protecting heart and promoting liver health | |
| CN101612254A (en) | A kind of pharmaceutical composition and preparation method thereof with resisting fatigue, immunoregulation effect | |
| CN102631489B (en) | Traditional Chinese medicine composition capable of improving immunity and resisting fatigue | |
| CN102631493B (en) | Health care composition | |
| CN102631389A (en) | Traditional Chinese medicine composition capable of improving immunity and resisting fatigue | |
| CN102631393B (en) | Health care composition | |
| CN102631496B (en) | Traditional Chinese medicine composition capable of improving immunity and resisting fatigue | |
| CN102631394B (en) | Traditional Chinese medicine composition capable of improving immunity and resisting fatigue |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20220915 Address after: 224100 6, Jinfeng South Street, Dafeng District, Yancheng City, Jiangsu. Patentee after: Dafeng District Productivity Promotion Center, Yancheng City Address before: Ji Hongjinzhuan, Development Department, Jiangsu Huifeng Agrochemical Co., Ltd., South Head of Wanggang Zha, Dafeng City, Yancheng City, Jiangsu Province, 224100 Patentee before: Yang Cuihong |
|
| EE01 | Entry into force of recordation of patent licensing contract | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20120815 Assignee: JIANGSU HUIFENG BIO AGRICULTURE Co.,Ltd. Assignor: Dafeng District Productivity Promotion Center, Yancheng City Contract record no.: X2023980042603 Denomination of invention: Traditional Chinese medicine composition for enhancing immunity and anti fatigue Granted publication date: 20130814 License type: Common License Record date: 20230926 |
|
| EE01 | Entry into force of recordation of patent licensing contract | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20120815 Assignee: DAFENG HEGNO PHARMACEUTICALS Co.,Ltd. Assignor: Dafeng District Productivity Promotion Center, Yancheng City Contract record no.: X2023980045165 Denomination of invention: Traditional Chinese medicine composition for enhancing immunity and anti fatigue Granted publication date: 20130814 License type: Common License Record date: 20231102 Application publication date: 20120815 Assignee: YANCHENG DESANO PHARMACEUTICAL Co.,Ltd. Assignor: Dafeng District Productivity Promotion Center, Yancheng City Contract record no.: X2023980045163 Denomination of invention: Traditional Chinese medicine composition for enhancing immunity and anti fatigue Granted publication date: 20130814 License type: Common License Record date: 20231102 Application publication date: 20120815 Assignee: JIANGSU BROTHER VITAMINS Co.,Ltd. Assignor: Dafeng District Productivity Promotion Center, Yancheng City Contract record no.: X2023980045158 Denomination of invention: Traditional Chinese medicine composition for enhancing immunity and anti fatigue Granted publication date: 20130814 License type: Common License Record date: 20231102 Application publication date: 20120815 Assignee: JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL Co.,Ltd. Assignor: Dafeng District Productivity Promotion Center, Yancheng City Contract record no.: X2023980045154 Denomination of invention: Traditional Chinese medicine composition for enhancing immunity and anti fatigue Granted publication date: 20130814 License type: Common License Record date: 20231102 |