CN102631393B - Health care composition - Google Patents

Health care composition Download PDF

Info

Publication number
CN102631393B
CN102631393B CN2012101219290A CN201210121929A CN102631393B CN 102631393 B CN102631393 B CN 102631393B CN 2012101219290 A CN2012101219290 A CN 2012101219290A CN 201210121929 A CN201210121929 A CN 201210121929A CN 102631393 B CN102631393 B CN 102631393B
Authority
CN
China
Prior art keywords
cordyceps
spirulina
hippocampus
herba epimedii
radix ginseng
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN2012101219290A
Other languages
Chinese (zh)
Other versions
CN102631393A (en
Inventor
杨翠红
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dafeng District Productivity Promotion Center Yancheng City
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN2012101219290A priority Critical patent/CN102631393B/en
Publication of CN102631393A publication Critical patent/CN102631393A/en
Application granted granted Critical
Publication of CN102631393B publication Critical patent/CN102631393B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

The invention provides a health care composition comprising cordyceps sinensis, ginseng, herba epimedii, spirulina and hippocampus japonicus. The composition has the functions of improving the human body immunity, resisting fatigue and treating impotence.

Description

A kind of health composition
Technical field
The invention belongs to the Chinese medicine health care product field, particularly a kind of health composition with raising body immunity, resisting fatigue and treatment sexual impotence.
Background technology
Along with socioeconomic continuous development, the raising day by day of people's living standard, people increase gradually to the degree of keeping a grip on of health, live in now all be, we receive many outside threats easily at everyone health, comprise air pollution, video pollution, environmental pollution, operating pressure, economic pressures, bacterial virus, improper diet etc.Moreover, because the variation of city work, rhythm of life is easy to make the people to produce confirmed fatigue, i.e. sub-health state, the factor of all these unfavorable health can be made us spiritual usually and can not concentrate, hypomnesis, often indolent and listless, old and feeble ahead of time.Therefore improve autoimmunity, the ability that strengthens the various unfavorable health factors of antagonism is most important.The health product that are used for enhancing human body immunity power on the market are of a great variety at present, but action effect is uneven.
Sexual impotence is common clinically male sexual disorder, refers to that when having libido to require, penis anorthosis or erection are not hard, thereby hinders sexual intercourse maybe can not finish sexual intercourse.This disease serious threat male's physical and mental health also is one of reason that causes male infertility, not only causes sizable psychology and physiological misery to the patient, and severe patient also may cause the breakdown of a family and become social problem.The reason that causes this symptom is more, is physiological on the one hand, is psychological on the one hand.The medicine for the treatment of sexual impotence is more at present, but most of curative effect is slow and undesirable, and side effect is bigger, is not suitable for taking for a long time, and the employing external used medicine is also arranged, but effective drug duration is short, can not meet the demands.
Summary of the invention
The present invention adopt the Chinese crude drug of five kinds of integration of edible and medicinal herbs to make a kind of compositions that has treatment sexual impotence effect and be of value to relaxing muscles and tendons and activating QI and blood in the collateral, and optional passing through is processed into the preparation that supplies peroral dosage form with said composition in order to remedy the deficiencies in the prior art.
The present invention is achieved through the following technical solutions: a kind of health composition, be made up of the raw material of following parts by weight: the parts by weight of each component are: Cordyceps 2-55 part, Radix Ginseng 4-60 part, Herba Epimedii 4-65 part, spirulina 3-65 part, hippocampus 3-60 part.Preferably, Cordyceps 4-30 part, Radix Ginseng 5-40 part, Herba Epimedii 4-35 part, spirulina 5-40 part, Hippocampus 5-40 part.
Preferably, the weight proportion of each component is: 55 parts of Cordycepses, 60 parts of Radix Ginsengs, Herba Epimedii 4-65 part, 65 parts of spirulinas, 60 parts of Hippocampus.
Preferably, the weight proportion of each component is: 2 parts of Cordycepses, 4 parts of Radix Ginsengs, 4 parts of Herba Epimedii, 3 parts of spirulinas, hippocampus 3 part.
Preferably, the weight proportion of each component is: 30 parts of Cordycepses, 40 parts of Radix Ginsengs, 35 parts of Herba Epimedii, 40 parts of spirulinas, 40 parts of Hippocampus.
Preferably, the weight proportion of each component is: 18 parts of Cordycepses, 20 parts of Radix Ginsengs, 30 parts of Herba Epimedii, 25 parts of spirulinas, 5 parts of hippocampus 3s.
Above-mentioned each component is selected, clean, drain, pulverize, mix, and namely gets compositions.Or adopting the extracting method of this area routine that above-mentioned each component is extracted, the extracting solution drying is mixed, and namely gets compositions.
Because five kinds of effective ingredient in the said composition all belong to the material of integration of edible and medicinal herbs, thereby said composition also can be used as nutrient and healthcare products, perhaps for the preparation of the purposes of nutrient and healthcare products.
Compositions of the present invention can directly be pulverized or through the active component of the refining compositions as treatment of the extraction of the conventional extractive technique in this area such as decoction and alcohol sedimentation technique or ethanol extract from water precipitation.Described active component can be made various pharmaceutical formulations with pharmaceutically acceptable carrier or excipient composition, as is how granular tablet, granule, capsule, or oral liquid etc.According to using needs, compositions of the present invention also can be processed into slow releasing preparation or quick releasing formulation.Wherein said pharmaceutically acceptable carrier or excipient are selected according to different dosage forms.These used carriers or excipient can determine for the those of ordinary skill of pharmaceutical field.
The preparation method of oral liquid, can but not only be confined to following a kind of, after active component is mixed, decoct with water, decoction liquor is filtered, obtain solution, the gained solution concentration is obtained extractum, then gained extractum be dissolved in 5-10 times of weight of extractum weight concentration in the ethanol water according to weight meter 95%, mix, quantitatively packing obtains oral liquid formulations.
The preparation method of tablet is that the active component mixture is sieved, and behind the auxiliary agent pulverizing commonly used with preparing tablet, abundant mix homogeneously, crosses the 40-80 eye mesh screen, by tabletting the direct machine of dry powder is pressed into tablet.
The preparation technology of capsule preparations can for, the active component mixture is sieved, pulverizing with the commonly used auxiliary agent of preparation tablet, fully behind the mix homogeneously, crossing the 40-80 eye mesh screen, by granulating, drying is irritated capsule after the operations such as granulate, polishing, packing gets product.
Medicinal and the health properties of each component that the present invention adopts is:
Cordyceps: related Cordyceps refers to the fungus (Cordyceps) and the bacterium worm coalition that larva forms of Clavicipitaceae among the present invention under specific condition, comprising: Cordyceps, Cordyceps hawkesii Gary, Cordyceps liangshanensis Zang Hu et Liu, the Xinjiang Cordyceps, the branch Cordyceps, leaves of pulse plants gram Cordyceps, Cordyceps militaris (L.) Link., the Wuyi Mountain Cordyceps, the dragon's cave-stalactite cave Cordyceps, the Zhangjiajie Cordyceps, big cat head Cordyceps, many shells Cordyceps, gentle handle Cordyceps, sagging Cordyceps, the Jiangxi Cordyceps, the Sichuan Cordyceps, Cordyceps oxycephala, bar grace Cordyceps, the Guizhou Cordyceps, the Chishui Cordyceps, the Dermaptera Cordyceps, intend the Bu Banke Cordyceps, Cordyceps martialis Speg., the Lou Shan Cordyceps, Mus tail Cordyceps, green nuclear Cordyceps, the moorland Cordyceps, luxuriant blue Cordyceps, BUSHICHONGCAO, Cordyceps takaomontana, yellowish Cordyceps militaris (L.) Link., the bulb Cordyceps, the chafer Cordyceps, the Mantidis Cordyceps, the froghopper Cordyceps, handle shell Cordyceps, intend luxuriant blue Cordyceps, Cordyceps gracilioides, the hair Cordyceps, the wireworm Cordyceps, the Japan Cordyceps, the Xin Kelai Cordyceps, beak shell Cordyceps, intend dark green Cordyceps, high eyebrow Cordyceps, FENBEICHONGCAO, Dayi Cordyceps, the fork-tail Cordyceps, the Caulis cyatheae spinulosae Cordyceps, the Aeschna melanictera Cordyceps, the ant Cordyceps, the Luo Baici Cordyceps, Cordyceps kyushuensis, the buttress shaft Cordyceps, DAISHICHONGCAO, the distortion Cordyceps, rice mountain Cordyceps, two shuttle spore Cordycepses, Cordyceps gunnii (Berk.) Berk. etc.Worm powder after Cordyceps among the present invention comprises Cordyceps and grinds, refine the back Cordyceps extract through processing, or have a form in each growth course of Cordyceps.Cordyceps has the function that tonifying the lung kidney, cough-relieving are coughed, benefit is deficient, support vital essence.According to clinical research, Cordyceps has ten big functions and has foster lung yin, and kidney-replenishing, relieving cough and resolving phlegm, anticancer anti-old effect are the product of flat nourishing YIN sun, all nothings avoid that (men and women, old and young can both eat, be to be fit to the widest tonic of crowd, and do not need to avoid certain food that health is had tonification greatly, mend marrow lung benefiting kidney, and property of medicine gentleness, do not attend a meeting like the people that the people is produced is scorching, the benefit of Radix Ginseng is arranged and do not have the evil of Radix Ginseng).Can be used for the pulmonary tuberculosis hemoptysis, diseases such as impotence and seminal emission.
Hippocampus: belong to net-rope, the Solenognathus order, the general name of Hippocampus animal belongs to bony fish.Hippocampus is the higher rare Chinese medicine of a kind of economic worth, contains aminoacid and protein, fatty acid, steroidal and inorganic elements.Its property is sweet, warm, go into liver, kidney channel, kidney invigorating and YANG supporting, regulating qi and activating blood is controlled sexual impotence, the enuresis, dyspnea due to deficiency, difficult labour, furuncle swelling toxin, and have medicinal functions such as building body, kidney invigorating and YANG supporting, relaxing muscles and tendons and activating QI and blood in the collateral, anti-inflammatory analgetic, tranquillizing and allaying excitement, relieving cough and asthma, particularly more effective for the neural disease for the treatment of.
Radix Ginseng: the general name for a kind of herbaceos perennial of the Umbellales Araliaceae Radix Ginseng Panax of family comprises Radix Ginseng Rubra, Radix Ginseng, Radix Panacis Quinquefolii (Radix Panacis Quinquefolii), Radix Glehniae, Radix Codonopsis and Radix Pseudostellariae etc.Radix Ginseng among the present invention comprises through processing and refines back Radix Ginseng extract, various forms in grinding descendant's pure extract powder or Radix Ginseng growth course.Sweet little hardship, warm in nature, go into spleen, lung meridian, strongly invigorating primordial QI promotes the production of body fluid admittedly take off, and calms the nerves.It is deficient to control impairment caused by overstrain, lack of appetite, and asthenia, food is told in regurgitation, the stool lingering diarrhea, empty cough with asthma is short, the spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, frequent micturition is quenched one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion, and prolonged deficiency is not multiple, the disease of all qi-blood-body fluid deficiencies.
Herba Epimedii: the Herba Epimedii that arrives involved in the present invention can be Berberidaceae plant Herba Epimedii, arrow leaf Herba Epimedii, pubescence Herba Epimedii, or the dried leaves of Herba Epimedii.Herba Epimedii among the present invention is hidden Herba Epimedii powder, icariin, icariin I, the Herba Epimedii A etc. through refining that comprise after grinding.Herba Epimedii has kidney-replenishing, bone and muscle strengthening, and the effect of wind-damp dispelling can improve body's immunity; Can expand all blood vessels, microcirculation improvement, blood flow increasing increases coronary flow.
Spirulina: involved in the present invention to spirulina refer to belong to a class rudimentary plant in Cyanophyta, Cyanophyceae, hormocystangium order, Oscillariaceae, the Spirullina, mainly comprise spirulina maxim, spirulina plalensis.Spirulina among the present invention comprises other processing forms of refining rear screw algae extract or spirulina through processing.Spirulina has Antiradiation injury effect, antibacterial action, antitumaous effect, photosensitization, to immune effect, cholesterol reducing, raising effectiveness, to protective effect of stomach etc.
In the component of the present invention, the Radix Ginseng strongly invigorating primordial QI, multiple arteries and veins takes off invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, the Fructus Alpiniae Oxyphyllae of calming the nerves, strong taste admittedly.Spirulina has the opsonic immunity function, cholesterol reducing, promoting digestion, protecting liver, anticancer, antidotal effect.Herba Epimedii has the enhancing human body immunity function, kidney-replenishing, and bone and muscle strengthening, wind-damp dispelling, microcirculation improvement, blood flow increasing increases coronary flow and antitussive, eliminates the phlegm, anti-hypoxia, calmness, anticonvulsant effect.Cordyceps has foster lung yin, kidney-replenishing, relieving cough and resolving phlegm, anticancer anti-old, regulate human body immunity and anti-fatigue ability.Hippocampus has building body, regulates immunocompetence, kidney invigorating and YANG supporting, and regulating qi and activating blood is controlled the effect of sexual impotence, tranquillizing and allaying excitement.Simultaneously, the present invention treats sexual impotence, and with kidney invigorating and YANG supporting, to fill blood be the rule for the treatment of, all medicines share and gather the effect of the kidney invigorating and essence nourishing, the strong body of tonifying YANG, blood enriching and dryness moistening altogether, and the sexual impotence that causes at a variety of causes has good curing, health-care effect.
The invention has the beneficial effects as follows:
Pharmaceutical composition of the present invention has benefiting QI for strengthening the superficies, improve the immunity of organisms effect, medicine of the present invention is not warm not dry, have invigorating spleen and reinforcing stomach, improve microcirculation in human body, the effect of wet dissipation eliminating impediment, enhancing immunity, resisting fatigue, antiviral, strengthening body, evident in efficacy, action temperature and, have no side effect.This medicine production technology is simple, be easy to take, and is a kind of desirable raising human immunity, the medicine of resisting fatigue.
Detailed description of the preferred embodiments
Following examples have illustrated the each aspect of the present invention content.They only in order to explanation, not delimit the scope of the invention.
Embodiment 1: the capsule that contains Cordyceps, Radix Ginseng, icariin, spirulina, Hippocampus
Cordyceps 55 grams, Radix Ginseng 60 grams, icariin 65 grams, spirulina 65 grams, Hippocampus 60 grams.
Above-mentioned Chinese medicine was soaked 40 minutes, it is important that the water surface is higher than raw material, add water total amount and be 8 times of total dose, the back little fire attitude of boiling of boiling is kept liquid level and is higher than raw material Chinese medicine height, decocts 2 hours, cross leaching filtrate, 6 times the water that adds total dose again, the back little fire attitude of boiling of boiling is kept liquid level and is higher than raw material Chinese medicine height, decocted 2 hours, filter to merge twice filtrate, through concentrating under reduced pressure (pressure 0.06MPa, 65 ℃ of temperature) to dried cream, pulverize, through 300 mesh sieves, add the magnesium stearate of gross weight 2%, incapsulate and get final product.
Embodiment 2: the tablet that contains Cordyceps, Radix Ginseng, spirulina, icariin, Hippocampus
Cordyceps 2 grams, Radix Ginseng 4 grams, icariin 4 grams, spirulina 3 grams, hippocampus 3 gram.Above-mentioned Chinese crude drug is dried and crushed into coarse powder, with the ethanol of 50-60% be solvent 60-70 ℃ of reflux, extract,, extracting solution is being gone out behind the ethanol, cryoconcentration becomes thick extractum, drying is ground into fine powder, sieves, mixing is granulated, and is pressed into tablet.
Embodiment 3: the capsule that contains Cordyceps, Radix Ginseng, icariin, spirulina, Hippocampus
Cordyceps 30 grams, Radix Ginseng 40 grams, icariin 35 grams, spirulina 40 grams, Hippocampus 40 grams.
Above-mentioned Chinese crude drug is dried and crushed into fine powder, sieves, mixing is packed into firmly softgel shell, makes Chinese medicine composition of the present invention.
Embodiment 4: the oral liquid that contains Cordyceps, Radix Ginseng, icariin, spirulina, Hippocampus
Cordyceps 10 grams, Radix Ginseng 25 grams, Herba Epimedii 40 grams, spirulina 30 grams, hippocampus 35 grams.
After the said components mixing, decoct with water, decoction liquor is filtered, obtain solution, the gained solution concentration is obtained extractum, gained extractum is dissolved in the concentration of 5-10 times of weight of extractum weight in the ethanol water according to weight meter 95% then, mix, quantitatively packing obtains oral liquid formulations.
Embodiment 5: the tablet that contains Cordyceps, Radix Ginseng, icariin, spirulina, Hippocampus
Cordyceps 8 grams, Radix Ginseng 12 grams, Herba Epimedii 40 grams, spirulina 15 grams, hippocampus 35 grams.
Above-mentioned Chinese crude drug is dried and crushed into coarse powder, with the ethanol of 50-60% be solvent 60-70 ℃ of reflux, extract,, extracting solution is being gone out behind the ethanol, cryoconcentration becomes thick extractum, drying is ground into fine powder, sieves, mixing is granulated, and is pressed into tablet.
Test example 1: the present invention tests effect of immunologic function
1, the product of testing product: embodiment 1, embodiment 2, embodiment 3, embodiment 4 and embodiment 5 is sample.
2, animal is used in detection: mice, rat, male and female half and half.
3, test basis: Ministry of Public Health " health food check and assessment technique standard " (2003 editions)
4, test item:
4.1 body weight, thymus/body weight ratio, spleen/body weight ratio
4.2comA the mouse spleen lymphocyte transformation experiment (mtt assay) of inducing
4.3 the tardy paraphilia reaction of the mice that dinitrofluorobenzene is induced (DTH)
4.4 antibody-producting cell detects (Jerne improves slide method)
4.5 serum hemolysin test
4.6 mice carbon clearance test
4.7 Turnover of Mouse Peritoneal Macrophages is engulfed chicken red blood cell experiment (dripping the sheet method)
4.8NK cytoactive is measured
5, testing result and judgement
5.1 the body weight of laboratory animal, thymus/body weight ratio, the testing result of spleen/body weight ratio shows, under this experimental condition, institute's full pattern product 500,1000,3000mg during kg (be equivalent to respectively be grown up per kg body weight per day recommended intake 5 times, 10 times, 30 times) dosage, five groups of samples are to the body weight of animal, thymus/body weight ratio, and spleen/body weight ratio there is no obvious influence.
5.2comA mouse spleen lymphocyte transformation experiment (mtt assay) result who induces shows that under this experiment condition, each dosage group optical density difference and solvent control class value relatively all do not have statistical significant difference (P>0.05).The prompting sample does not have the mouse lymphocyte of enhancing multiplication capacity.
5.3 the tardy paraphilia reaction of the mice that dinitrofluorobenzene is induced is (DTH) result show, under this experiment condition, each dosage group optical density difference and solvent control class value compare, and five groups of samples all do not have statistical significant difference (P>0.05).The prompting sample has the tardy paraphilia reagentia of mice that the enhancing dinitrofluorobenzene causes.The test dose group is positive, and the prompting sample can strengthen the mouse cell immunologic function.
5.4 detecting (Jerne improves slide method) result, antibody-producting cell shows, under this experimental condition, each dosage group hemolysis plaque number average is higher than the solvent control class value, and low, middle dosage group has statistically-significant difference (P<0.05), and the prompting sample has the ability that mice produces antibody producing cells that strengthens.
5.5 the serum hemolysin result of the test shows that under this experiment condition, each dosage group mice serum half hemolysis value and solvent control class value relatively all do not have statistically-significant difference (P>0.05).The prompting sample does not have the ability that mice produces serum hemolysin that strengthens.The dosage group of five groups of sampling tests is all positive, and the prompting sample can strengthen the mouse humoral immune function.
5.6 the clearance test of mice carbon is the result show, under this experiment condition, each dosage group mice engulf tree planting A and solvent control class value relatively, all do not have statistical significant difference (P>0.05).Prompting sample five strengthens the effect that carbon is cleaned up ability.
5.7 engulfing chicken red blood cell experiment (dripping the sheet method) result, Turnover of Mouse Peritoneal Macrophages shows, under this experimental condition, the monokaryon of each sample and each dosage group mice-macrophage phagocytic percentage rate and phagocytic index and solvent control class value relatively all do not have statistical significant difference (P>0.05).Prompting sample five strengthens the effect of Turnover of Mouse Peritoneal Macrophages phagocytic activity.Result of the test is all negative, and the prompting sample does not have enhancing mouse monokaryon-macrophage phagocytic function.
5.8NK the cytoactive measurement result shows, under this experimental condition, the NK cytoactive of each dosage group mice all is higher than the solvent control class value, and high dose group has statistical significant difference (P<0.05), the effect that the prompting sample has the NK cytoactive that strengthens mice.
Comprehensive above result of the test, according to health food enhancing immunity functional evaluation standard, 5 samples of prescription of the present invention all have the function of enhancing immunity.
Test example 2: the present invention is to improving the clinical efficacy of immune function of human body
The child: immunologic hypofunction, easy catching a cold, average every month more than twice, or suffer from twice above patient of pneumonia in 1 year.
Elderly patients: suffer from multiple chronic disease, be diagnosed as the patient of syndrome of deficiency of lung qi.
2, method of administration and the course for the treatment of:
The preparation of oral embodiment of the invention 1-4 embodiment.Contrast: the single agent capsules of Cordyceps, icariin capsule.
Adult: each 3 examples, every day 3 times.
Child below 6 years old: each 1, every day 2-3 time.
Child more than 6 years old: each 2, each 2-3 time.
Above patient was a course for the treatment of with one month all, and it treats 1-3 the course for the treatment of.
3, observational technique:
Carry out blood, urine, just routine test and the heart, pulmonary function test, and observe: heating, aversion to cold, sniffle, pharyngeal symptom and whole body situation and the temperature of having a medical check-up, pharyngeal tonsil, the picture of the tongue pulse condition, therapeutic evaluation is carried out in variations such as fingerprint respectively.
4, therapeutic evaluation
Table one prescription of the present invention improves the clinical observation of immune function of human body
Compositions The example number Obviously improve Improve Invalid Total improvement rate %
Embodiment 1 98 80 10 8 91.8
Embodiment 2 105 83 10 12 88.6
Embodiment 3 109 88 8 13 88.1
Embodiment 4 115 89 14 12 88.6
Embodiment 5 98 78 11 9 90.8
Contrast (capsule of Chinese caterpillar fungus) 42 19 6 17 59.5
Contrast (icariin capsule) 41 6 17 18 56.1
Drug side effect of the present invention: period in a medicine small number of patients xerostomia, outside the dry stool, all there is not any untoward reaction, drug withdrawal or decrement, mouthfeel, dry stool transference cure.
Test example 3: the present invention is to the influence test of mouse anti-reflecting fatigue
Preparation of the present invention (embodiment 1, embodiment 2, embodiment 3, embodiment 4, embodiment 5) is to mouse anti-reflecting fatigue influence test.90 of mices are divided into six groups at random, press the gastric infusion of dosage shown in the table 2, and every day 1 time, continuous 10 days, normal control group and model group gave the equal-volume distilled water, and volume is 20ml/kg.And in first day on-test.After the last administration 1 hour, animal is put into 15 ± 1 ℃ swimming groove, observe mice and put into water and be sink to the water-bed unable time of floating again for continuing swimming time.The results are shown in Table 2. by table 2 result as seen, compositions of the present invention can obviously prolong mice low temperature and continue swimming time.
Table 2. preparation of the present invention is to the influence of mice swimming time
Figure BDA0000156383930000071
Figure BDA0000156383930000081
Result of the test shows, but preparation significant prolongation mice low temperature of the present invention continues swimming time.Show that the present invention has the ability of resisting fatigue to mice.
Test example 4: the present invention is to impotence patient's clinical treatment
(1) clinical data
2009 are so far, and the preparation that the inventor utilizes embodiment 1 and embodiment 2 to make carries out clinical observation treatment to 285 routine impotence patients, wherein, and age 20-30 year, 54 examples; 31-40 year, 73 examples, 41-50 year, 66 examples, 51-60 year, 58 examples, more than 60 years old, 34 examples.Sexual impotence reason: sexual impotence 36 examples due to sexual impotence 38 examples due to psychic impotence 44 examples, nephropathy, hepatopathy, incretion sexual impotence 34 examples, sexual hypofunction (lowly) person 75 examples, psychogenic sexual impotence 26 examples, arteriosclerotic sexual impotence 22 examples, unknown cause sexual impotence 10 examples.Contrast medicament: icariin list agent capsules.
(2) Therapeutic Method
Compositions of the present invention, warm water is for oral administration, and three times on the one, each 3-6g, one after each meal.Calculate treatment time according to the conditions of patients weight, patients with mild was taken 3 months, and the severe case serve on 6 months.
(3) curative effect determinate standard
Cure: after the treatment phase, erection is greater than 90 degree, and success rate of sexual intercourse is more than or equal to 80%.
Produce effects: after the treatment phase, erection is greater than 90 degree, and success rate of sexual intercourse is more than or equal to 50%.
Effectively: after the treatment phase, the erection situation makes moderate progress,, success rate of sexual intercourse is more than or equal to 30%.
Invalid: every index does not all have improvement before and after the medication.
(4) clinical effectiveness
Figure BDA0000156383930000082
Figure BDA0000156383930000091
Clinical trial shows, the present invention has excellent therapeutic effect to impotence patient, reaches more than 90% for patient's total effective rate of age less than 50 years old, along with the increase therapeutic effect at age also decreases, but still has curative effect preferably with comparing.

Claims (7)

1. a health composition is characterized in that being made up of Cordyceps, Radix Ginseng, Herba Epimedii, spirulina and Hippocampus, and the parts by weight of each component are: Cordyceps 2-55 part, Radix Ginseng 4-60 part, Herba Epimedii 4-65 part, spirulina 3-65 part, hippocampus 3-60 part.
2. compositions according to claim 1 is characterized in that the parts by weight of each component are: Cordyceps 4-30 part, Radix Ginseng 5-40 part, Herba Epimedii 4-35 part, spirulina 5-40 part, Hippocampus 5-40 part.
3. compositions according to claim 1 and 2 is characterized in that the Herba Epimedii in the said composition is icariin.
4. compositions according to claim 1 is characterized in that said composition is the preparation of peroral dosage form.
5. the described compositions of claim 1 improves human body immunity's health product or the purposes in the medicine in preparation.
6. the described compositions of claim 1 strengthens the health product of human body anti-fatigue ability or the purposes in the medicine in preparation.
7. the described compositions of claim 1 is in the health product of preparation treatment sexual impotence or the purposes in the medicine.
CN2012101219290A 2012-04-24 2012-04-24 Health care composition Active CN102631393B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2012101219290A CN102631393B (en) 2012-04-24 2012-04-24 Health care composition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2012101219290A CN102631393B (en) 2012-04-24 2012-04-24 Health care composition

Publications (2)

Publication Number Publication Date
CN102631393A CN102631393A (en) 2012-08-15
CN102631393B true CN102631393B (en) 2013-08-28

Family

ID=46616073

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2012101219290A Active CN102631393B (en) 2012-04-24 2012-04-24 Health care composition

Country Status (1)

Country Link
CN (1) CN102631393B (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1456204A (en) * 2003-01-03 2003-11-19 江西南昌桑海制药厂 Oral liquid for tonifying Qi and kidney
CN101862355A (en) * 2010-07-07 2010-10-20 郭景龙 Medicine compound having function of promoting immunity

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1456204A (en) * 2003-01-03 2003-11-19 江西南昌桑海制药厂 Oral liquid for tonifying Qi and kidney
CN101862355A (en) * 2010-07-07 2010-10-20 郭景龙 Medicine compound having function of promoting immunity

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
《中医对阳痿治疗研究概况》;戴双明等;《中医对阳痿治疗研究概况》;19991231;第20卷(第11期);477-478 *
《中医治疗阳痿选方》;刘国立;《开卷有益求医问药》;19961231(第1期);21-22 *
《现代中医药方剂在抗运动性疲劳中的应用》;高顺生;《中国临床康复》;20051231(第12期);201 *
《食品与免疫》;刘绍;《中国食物与营养》;20040528;第9卷(第5期);57-58 *
刘国立.《中医治疗阳痿选方》.《开卷有益求医问药》.1996,(第1期),21-22.
刘绍.《食品与免疫》.《中国食物与营养》.2004,第9卷(第5期),57-58.
戴双明等.《中医对阳痿治疗研究概况》.《中医对阳痿治疗研究概况》.1999,第20卷(第11期),477-478.
高顺生.《现代中医药方剂在抗运动性疲劳中的应用》.《中国临床康复》.2005,(第12期),201.

Also Published As

Publication number Publication date
CN102631393A (en) 2012-08-15

Similar Documents

Publication Publication Date Title
CN103719498B (en) A kind of Siberian solomonseal rhizome health-care tea improving immunity and preparation method thereof
CN102631494B (en) Traditional Chinese medicine composition capable of improving immunity and resisting fatigue
CN104489172A (en) Acanthopanax health tea for improving immunity and preparation method thereof
CN104206595A (en) Blood lipid and blood glucose reducing Chinese wolfberry root-bark health care tea and preparation method thereof
CN105902827A (en) Traditional Chinese medicine composition for improving immunity of human body and preparation method thereof
CN102631492B (en) Chinese medicinal composition for improving immunity and resisting fatigue
CN111298020B (en) Traditional Chinese medicine composition with anti-fatigue effect and preparation method and application thereof
CN102631486B (en) Health care composition
CN102631490B (en) Traditional Chinese medicine composition capable of improving immunity and resisting fatigue
CN102631506B (en) Traditional Chinese medicine composition capable of improving immunity and resisting fatigue
CN102631487B (en) Traditional Chinese medicine composition capable of improving immunity and resisting fatigue
CN102631498B (en) Chinese medicinal composition
CN106924581A (en) It is a kind of to treat medicinal liquor of stomachache and preparation method thereof
CN103238834B (en) A kind of composition treating pruitus and preparation method thereof
CN102631393B (en) Health care composition
CN102631493B (en) Health care composition
CN102631488B (en) Traditional Chinese medicine composition capable of improving immunity and resisting fatigue
CN102631496B (en) Traditional Chinese medicine composition capable of improving immunity and resisting fatigue
CN102631389A (en) Traditional Chinese medicine composition capable of improving immunity and resisting fatigue
CN104256618A (en) Food, health care product or medicine composition with blood sugar reduction function
CN107596013A (en) A kind of extracting method of maca and its male health-care product of preparation
CN102631394B (en) Traditional Chinese medicine composition capable of improving immunity and resisting fatigue
CN102631489B (en) Traditional Chinese medicine composition capable of improving immunity and resisting fatigue
CN108815342B (en) Traditional Chinese medicine composition for treating male infertility
CN102631491A (en) Chinese medicinal composition for improving immunity and resisting fatigue

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20220919

Address after: 224100 6, Jinfeng South Street, Dafeng District, Yancheng City, Jiangsu.

Patentee after: Dafeng District Productivity Promotion Center, Yancheng City

Address before: Ji Hongjinzhuan, Development Department, Jiangsu Huifeng Agrochemical Co., Ltd., South Head of Wanggang Zha, Dafeng City, Yancheng City, Jiangsu Province, 224100

Patentee before: Yang Cuihong

EE01 Entry into force of recordation of patent licensing contract
EE01 Entry into force of recordation of patent licensing contract

Application publication date: 20120815

Assignee: JIANGSU HUIFENG BIO AGRICULTURE Co.,Ltd.

Assignor: Dafeng District Productivity Promotion Center, Yancheng City

Contract record no.: X2023980042603

Denomination of invention: A health composition

Granted publication date: 20130828

License type: Common License

Record date: 20230926

EE01 Entry into force of recordation of patent licensing contract
EE01 Entry into force of recordation of patent licensing contract

Application publication date: 20120815

Assignee: DAFENG HEGNO PHARMACEUTICALS Co.,Ltd.

Assignor: Dafeng District Productivity Promotion Center, Yancheng City

Contract record no.: X2023980045165

Denomination of invention: A health composition

Granted publication date: 20130828

License type: Common License

Record date: 20231102

Application publication date: 20120815

Assignee: YANCHENG DESANO PHARMACEUTICAL Co.,Ltd.

Assignor: Dafeng District Productivity Promotion Center, Yancheng City

Contract record no.: X2023980045163

Denomination of invention: A health composition

Granted publication date: 20130828

License type: Common License

Record date: 20231102

Application publication date: 20120815

Assignee: JIANGSU BROTHER VITAMINS Co.,Ltd.

Assignor: Dafeng District Productivity Promotion Center, Yancheng City

Contract record no.: X2023980045158

Denomination of invention: A health composition

Granted publication date: 20130828

License type: Common License

Record date: 20231102

Application publication date: 20120815

Assignee: JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL Co.,Ltd.

Assignor: Dafeng District Productivity Promotion Center, Yancheng City

Contract record no.: X2023980045154

Denomination of invention: A health composition

Granted publication date: 20130828

License type: Common License

Record date: 20231102