A kind of Chinese medicine and health food with liver protecting effect
Technical field
The invention belongs to Chinese medicine and health food field, relate to a kind of herbal mixture health food with liver protecting effect.
Background technology
Liver is that the students from five types of universities that body weight for humans is wanted order one of organ, to maintaining people's normal activities, has irreplaceable effect.Liver is also the removing toxic substances organ of human body maximum, yet liver is the most responsive, fragile.Do not have enough sleep, fat, blood sugar is too high, excessive drinking, smoking, stay up late, drug abuse, rich food dish, all can increase the weight of the burden of liver and injure liver, and then transfer chronic liver injury, hepatitis to, finally develop into liver cancer.Liver diseases has become serious harm health " assailant ".Due to the not significant especially symptom of hepatopathy, that patient shows is tired out, abdominal distension, collywobbles, jaundice, poor appetite, feel sick, the symptom such as fever is easy to be left in the basket, and be called as " maximum stealthy killer ", even if liver is had minor illness, can not reveal at once yet, thereby early detection hepatopathy is more difficult, yet, once display just very thorny.As the fatty liver, the alcoholic liver that rise gradually in recent years have become the healthy a kind of common property disease of a kind of people of having a strong impact on.Liver protecting seems further important to busy modern.
Theory of traditional Chinese medical science is thought, " control liver and first control spleen ", the liver belonging to wood, spleen pertaining to the earth, edema with the liver involved gram spleen soil, liver is being brought into play the effect of adjusting, restriction to spleen in other words, and this restriction or checking relation in five elements relation contributes to the mutual coordination of function between internal organs.In the traditional Chinese medical science, the function of taste is conditions that human body obtains all nutriments, there is no nutriment, and existence is all a problem, and has let alone treatment disease.So taste are the basic of human body daily life, activity (day after tomorrow).So, when improving liver function, must focus on the adjusting of taste, just can play better regulating action.
Modern medicine proves, people's digestive system mainly comprises stomach, small intestine, large intestine and liver.Stomach is the immune organ of human body maximum, and the major function of enteron aisle is to digest and assimilate, and the main task of liver is purification, metabolism and utilization.Though stomach and intestine and liver have the different division of labor, but cooperatively interact, complement each other, either party can affect whole digestion and absorption function at insufficiency, there is no digesting and assimilating of stomach and intestine, and liver just embarrasses and cooks a meal without rice; The purification removing toxic substances and the Absorption And Metabolism that there is no liver, nutrient just can not be converted into the thing that health can be used, the accumulation of these nutrients, adds the not toxin of solution, will cause great injury to human body, angle from health and health care, only protected liver and supported prosperous stomach Qi, the strong the foundation of acquired constitution of ability, needs liver stomach with supporting so protect liver, it is good to only have the maintenance of liver stomach, just can win the first chance of health.
Modern medicine there is no specific medicament aspect the treatment of hepatic injury, and nutrition, replenishing vitamins or symptomatic treatment etc. are had a rest, strengthened to adopt more.Chinese medicine has health care, and by dialectical prescription, science compatibility, finds the herbal mixture health food with liver protecting effect, strengthens daily health caring, prevents trouble before it happens, significant for prevention of liver disease.
Summary of the invention
The present invention is based on integration of drinking and medicinal herbs, reinforcement daily health caring is starting point, and object is to provide a kind of Chinese medicine and health food with liver protecting effect.
For realizing the object of the invention, technical scheme is as follows: this adopts following bulk drug to be prepared from, and each component percentage by weight is: date 5-40%, raw eastern short, bristly hair or beard 5-40%, FRUCTUS SCHISANDRAE from Liaoning of China 5-40%, Poria cocos 5-40%, fruit of Chinese wolfberry 3-30%.
Be preferably as follows component: date 20-30%, raw eastern short, bristly hair or beard 20-30 %, FRUCTUS SCHISANDRAE from Liaoning of China 20-30%, Poria cocos 20-30%, the fruit of Chinese wolfberry 10-20 %.
Above proportioning, adds auxiliary material, granulation agent according to a conventional method, mixture, pill, capsule, tablet etc.Be preferably as follows preparation method: by above proportioning, raw material is pulverized, mixed, boiling 2 times, 1 hour for the first time, 0.5 hour for the second time, merge extract, filter, concentrated, add auxiliary material, make various form of Chinese drug.
In side, date taste is sweet, warm in nature.Return spleen, stomach warp.Tonifying middle-Jiao and Qi, nourishing blood and tranquilization.The traditional Chinese medical science is commonly used red date nourishing stomach and spleen.When met the more violent or irritant medicine of the efficacy of a drug in prescription, Chang Peiyong red date, with protecting the spleen and stomach.In red date, contained carbohydrate, fat, protein is liver-protective nutritional agents.It can promote liver synthetic proteins, increase serum Lactoferrin and albumin content, adjust albumin and globulin ratio, have prevention transfusion reaction, reduce the effects such as serum GPT levels, red date also has good therapeutic effect to illnesss such as chronic hepatitis, cirrhosis, anaemia, anaphylactoid purpuras.
Poria cocos, taste is sweet, light, property flat, enters the heart, spleen, liver, kidney channel, has the function of mending brain and enhancing fitness, clearing damp and promoting diuresis, beneficial spleen and stomach, antitoxic heart-soothing and sedative, is described as one of Chinese medicine " eight delicacies ".Modern medicine study: Poria cocos energy enhanced machine body immunity function, pachymaran has significantly antitumor and protect the liver dirty effect.The feature of Poria cocos is to mend and not high, and profit is not and violent, and the property of medicine is gentle, can righting, and again can be eliminating evil.Insufficiency of the spleen with overabundance of dampness person must be indispensable.
Fruit of Chinese wolfberry taste is sweet, property flat, has the effect of liver-kidney tonifying, says " take for a long time hard muscles and bones, make light of one's life by commiting suicide not old, cold-resistant heat " in < < Compendium of Materia Medica > >.The traditional Chinese medical science conventional it treat liver-kidney Yin deficiency, soreness and weakness of waist and knees, dizziness, forgetful, dizzy, the many tear of blurred vision, quench one's thirst, the illness such as seminal emission.Modern pharmacology studies confirm that the adjustable body's immunity of the fruit of Chinese wolfberry, can effectively suppress tumor growth and cell mutation, have delay senility, the effect of AFL, adjusting blood fat and the aspect such as blood sugar, promotion hematopoiesis function, and be applied to clinical.Matrimony vine have reduce blood pressure, the effect of blood fat and blood sugar, can atherosclerosis, protection liver, resists fatty liver, promotes liver cell regeneration.
Raw eastern short, bristly hair or beard, has another name called east and looks into, slightly warm in nature, and taste is sweet, sour.Have and disappear long-pendingly, the row stasis of blood, changes stagnant effect.Except promoting digestion, appetite-stimulating indigestion-relieving, also there is the effects such as liver-protecting and blood fat-reducing, promoting blood circulation and removing blood stasis, anti-ageing, softening blood vessel, step-down.Its composition contains a large amount of dietary fibers and trace element.Research shows, hawthorn enters after stomach, can strengthen the effect of enzyme, promotes carnivorous digestion, contributes to cholesterol to transform, and it contains ursolic acid, can reduce animal tallow in the deposition of vascular wall.For fatty liver or overweight people, eat a little hawthorn, haw flakes, Crataegi pill or drink etc. with hawthorn is soaked, the degrease that all can help digestion, is good food with effect of hepatic protection.
FRUCTUS SCHISANDRAE from Liaoning of China, has another name called fructus schisandrae, and warm in nature, taste is sour sweet, has the effect of astringent or styptic treatment for spontaneous sweating, the nourishing generate fluid of convergence, kidney calming.Clinical research discovery, this medicine can be repaired impaired liver cell to a certain extent, suppresses the activity of glutamic-pyruvic transaminase, and the immunologic mechanism of balance the body reduces transaminase and liver-protective effect thereby play.
In this prescription, required medicinal material is common integration of drinking and medicinal herbs article, meet the < < of Ministry of Public Health's announcement about the pertinent regulations of the notice > > of further standard healthy food material management, safe and reliable, nontoxic to human body.
The present invention, according to the pathogenic characteristic of traditional Chinese medical science taste mistake department, liver and gall discord, wet poly-phlegm resistance, qi depression to blood stasis, controls with clearing damp and reduces phlegm, promoting blood circulation and removing blood stasis, 'Shugan Lidan ', and regulating spleen and stomach, liver protecting, through clinical practice for many years, has developed this liver protecting health products.The present invention is pure Chinese medicinal preparation; a large amount of clinical practices and zoopery show; it can protect liver well, alleviates and eliminates hepatic injury, can regulate and reduce blood lipid level; correct dyslipidemia; can alleviate or remove fatty liver or alcoholic liver, can use for a long time, the diseases such as fatty liver, alcoholic liver, high fat of blood are had to good prevention or auxiliary therapeutic action; having embodied the features such as modern Chinese herbal medicine compound is safe, effective, stable, controlled, convenient, is the health-care good product of protecting and nourishing liver.Integration of drinking and medicinal herbs, nontoxic to human body, safe, can reach lipopenicillinase, invigorating spleen to remove dampness, benefiting qi and nourishing blood, dispersing stagnated hepatoqi, the effect such as protect that liver protects the liver.Cure rate reaches more than 82%, efficiently reaches 92%.
Through 296 routine clinical observations, its result is as follows:
Cure rate=244/296 * 100%=82%; Efficient=271/296 * 100%=92%.
The specific embodiment
For the present invention is illustrated better, as follows for embodiment:
Embodiment 1 granular preparation
The raw eastern short, bristly hair or beard 350g FRUCTUS SCHISANDRAE from Liaoning of China 300g of date 320g
Poria cocos 350g fruit of Chinese wolfberry 220g
The above five tastes, pulverize, and mix, boiling 2 times, 1 hour for the first time, 0.5 hour for the second time, merge extract, filter, concentrated, add suitable auxiliary material, dry (75-80 ℃ of vacuum drying), pulverizes, (100 order) sieves, powder is with appropriate amount of ethanol granulation, and dry (80-85 ℃ of vacuum drying), obtains.
Embodiment 2 mixture
The raw eastern short, bristly hair or beard 280g FRUCTUS SCHISANDRAE from Liaoning of China 320g of date 250g
Poria cocos 350g fruit of Chinese wolfberry 260g
The above five tastes, pulverize, and mix boiling 2 times, 1 hour for the first time, 0.5 hour for the second time, merge extract, filter, being concentrated into relative density is 1.10 ~ 1.14 (80 ℃), adds ethanol and makes to reach 60% ~ 65% containing alcohol amount, stirs evenly standing 24h, filter, filtrate recycling ethanol, adds Sodium Benzoate, refined honey, adds water and mixes, and filters, embedding, sterilizing, obtains.
Application examples zoopery
The embodiment of the present invention 2 products are processed into 1g/mL, 3g/mL, the basic, normal, high drug concentration of 6g/mL.Adopt the modeling of carbon tetrachloride hepatic injury modelling, 60 rats are divided into 5 groups at random, A group is Normal group, B organizes negative reference substance, and C, D, E group are respectively basic, normal, high dosage group, and 3 dosage group gavages every day give tested material, every day 10ml/kg(body weight), Normal group and model control group gavage give distilled water, give continuously 30 d, claim weekly twice body weight and adjust dosage according to body weight.Then get the content that liver checks MDA (MDA), reduced glutathione (GSH) and triglycerides (TG) in LH.Research the data obtained adopts SPSS 13.0 softwares to carry out statistical analysis, and enumeration data adopts chi-square criterion, and the P<0.05 of take has statistical significance as difference.
The results are shown in Table 1:
Table 1 is respectively organized LH MDA, reduced form GSH, TG level comparison (x ± s)
By above data, can be found out, under the condition of setting up at carbon tetrachloride hepatic injury model, the TG content of 3 dosage groups is starkly lower than model control group (p<0.05), the MDA content of middle and high dosage group is starkly lower than model control group (p<0.01), and liver MDA, TG, reduction GSH index have two indexs to be positive.
Table 2 is respectively organized glutamic-pyruvic transaminase (ALT), glutamic-oxalacetic transaminease (AST) content comparison (x ± s)
Detection to glutamic-pyruvic transaminase in serum (ALT), glutamic-oxalacetic transaminease (AST) content shows, the ALT of model control group, AST compared with normal group significantly raise (p<0.05), the ALT of 3 dosage groups, AST content are starkly lower than model control group (p<0.05), and high dose group is having conspicuousness reducing effect (p<0.01) compared with model group aspect reduction ALT, AST.
Above experimental fact explanation, this invention product has assistant protection function to chemical damage.
Model case
Provide the several concrete model case of edible product of the present invention below:
Lee, man, 36 years old, 175 centimetres of heights, 190 jin of body weight.Because daily dinner party is more, often drink beyond one's capacity, smoking addiction, fatty liver moderate 3 years, transaminase is high, takes product of the present invention after 1 month, fatty liver and transaminase level be improved significantly, body & mind state has very large improvement.
Wang, female, 48 years old, because of long-term higher fatty acid, high protein, the high-carbohydrate food taken in, cause health serious overweight and cause " nutrient imbalance " fatty liver, edible product of the present invention is after 1 month, liver is uncomfortable obviously to be alleviated, adhere to using after 3 months, fatty liver is removed completely, and immunity of organisms also significantly strengthens.
Beam, man, 55 years old, suffer from fatty liver for a long time, decreased liver function, immunity function is poor, and check result shows that there is minor injury in liver, uses product of the present invention after 1 month, and liver function is obviously improved, and sleep quality and the state of mind are significantly increased.