CN102626517B - 调节造血干细胞生长的方法 - Google Patents

调节造血干细胞生长的方法 Download PDF

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CN102626517B
CN102626517B CN201210050521.9A CN201210050521A CN102626517B CN 102626517 B CN102626517 B CN 102626517B CN 201210050521 A CN201210050521 A CN 201210050521A CN 102626517 B CN102626517 B CN 102626517B
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pge2
hsc
stem cell
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hematopoietic stem
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CN102626517A (zh
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L·I·宗
T·E·诺思
W·戈斯林
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General Hospital Corp
Boston Childrens Hospital
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/02—Compounds of the arachidonic acid pathway, e.g. prostaglandins, leukotrienes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Materials For Medical Uses (AREA)
CN201210050521.9A 2006-03-24 2007-03-26 调节造血干细胞生长的方法 Active CN102626517B (zh)

Applications Claiming Priority (3)

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US78596806P 2006-03-24 2006-03-24
US60/785,968 2006-03-24
CN200780018870XA CN101495623B (zh) 2006-03-24 2007-03-26 调节造血干细胞生长的方法

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CN102626517B true CN102626517B (zh) 2015-07-29

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EP (3) EP2423303A1 (enExample)
JP (8) JP5247675B2 (enExample)
CN (2) CN102626517B (enExample)
AU (1) AU2007230902B2 (enExample)
CA (1) CA2647201C (enExample)
MX (3) MX373998B (enExample)
RU (2) RU2425876C2 (enExample)
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ZA (2) ZA200808123B (enExample)

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US20090285786A1 (en) 2009-11-19
JP2019094347A (ja) 2019-06-20
US20120189594A1 (en) 2012-07-26
ZA200808123B (en) 2010-03-31
JP2022025091A (ja) 2022-02-09
JP2019214620A (ja) 2019-12-19
AU2007230902A1 (en) 2007-10-04
JP2023112027A (ja) 2023-08-10
EP2423303A1 (en) 2012-02-29
JP2015232010A (ja) 2015-12-24
US9028811B2 (en) 2015-05-12
RU2011115827A (ru) 2012-10-27
AU2007230902B2 (en) 2013-03-14
US20130216507A1 (en) 2013-08-22
CA2647201A1 (en) 2007-10-04
JP6041711B2 (ja) 2016-12-14
JP6208719B2 (ja) 2017-10-04
CN102626517A (zh) 2012-08-08
CA2647201C (en) 2016-03-08
US20120189593A1 (en) 2012-07-26
US20130209423A1 (en) 2013-08-15
RU2493252C2 (ru) 2013-09-20
CN101495623B (zh) 2013-09-11
US8168428B2 (en) 2012-05-01
MX373998B (es) 2020-07-22
WO2007112084A2 (en) 2007-10-04
EP3424507A1 (en) 2019-01-09
JP2016210802A (ja) 2016-12-15
US8551782B2 (en) 2013-10-08
JP5247675B2 (ja) 2013-07-24
WO2007112084A8 (en) 2008-11-20
WO2007112084A3 (en) 2009-01-08
JP6797222B2 (ja) 2020-12-09
JP2013155175A (ja) 2013-08-15
JP6530732B2 (ja) 2019-06-12
AU2007230902A8 (en) 2009-07-23
JP2009530408A (ja) 2009-08-27
HK1173948A1 (en) 2013-05-31
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US8563310B2 (en) 2013-10-22
EP1999255A2 (en) 2008-12-10
US10278990B2 (en) 2019-05-07
RU2425876C2 (ru) 2011-08-10
RU2008142106A (ru) 2010-04-27
MX2008012178A (es) 2009-01-23
WO2007112084A9 (en) 2007-11-22
ZA200906574B (en) 2010-06-30
US20120189592A1 (en) 2012-07-26
US20130209424A1 (en) 2013-08-15
CN101495623A (zh) 2009-07-29

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